Lecturer in Pharmaceutical Chemistry / NMR Spectroscopist
Cavanagh Pharmacy Building
University College Cork
College Road
Cork
T: 021 490 1793/1670
E: l.bateman@ucc.ie

Dr Lorraine Bateman obtained her degree in Chemistry & Applied Chemistry from NUI, Galway where she also studied for her PhD, graduating in 2006.  Her doctoral research was conducted in the area of chiral diamide ligand synthesis and asymmetric catalysis under the supervision of Dr. Simon W. Breeden and Dr. Patrick O’Leary.  She subsequently worked as an industrial research chemist in the area of chiral phosphine ligand synthesis with Celtic Catalysts Ltd.  She joined University College Cork as a NMR Spectroscopist at the Analytical and Biological Research Facility at University College Cork.  In 2014, Lorraine was awarded an SFI Advance Award to pursue independent research in the area of Quantitative NMR Spectroscopy. In 2017, she was appointed as Lecturer in Pharmaceutical Chemistry. 

Research Interests

Nuclear Magnetic Resonance Spectroscopy encompassing the following areas of application:

  • Small Molecule Characterisation
  • Quantitative NMR
  • Molecular Structure and Stereochemistry Determination
  • Conformational Analysis
  • Pharmaceutical/Biological/Food Science Applications
  • Multidimensional & Multinuclear Techniques
  • Reaction Monitoring
  • Reaction Kinetics
  • Dynamic Processes
  • Metabolomics/Metabonomics

Research Grants

 ProjectFunding
Body
Start DateEnd DateAward
ENSNARE Expanding NMR Spectroscopy as a key technique in pharmaceutical process chemistry through New Advancements across Research and EnterpriseScience Foundation Ireland

Peer Reviewed Journals

YearPublication
(2017)'Intramolecular Direct Arylation of 1,3-Diketone-Derived Enol Ethers in a Synthesis of Tricyclic Oxoisochromene Derivatives'
Muimhneachain, EO;Pardo, LM;Bateman, LM;Khandavilli, UBR;Lawrence, SE;McGlacken, GP (2017) 'Intramolecular Direct Arylation of 1,3-Diketone-Derived Enol Ethers in a Synthesis of Tricyclic Oxoisochromene Derivatives'. Advanced Synthesis and Catalysis, 359 :1529-1534 [DOI] [Details]
(2016)'Cyclization of 4-Phenoxy-2-coumarins and 2-Pyrones via a Double C-H Activation'
Mackey K;Pardo LM;Prendergast AM;Nolan MT;Bateman LM;McGlacken GP; (2016) 'Cyclization of 4-Phenoxy-2-coumarins and 2-Pyrones via a Double C-H Activation'. Organic letters, 18 (11) [DOI] [Details]
(2015)'A study of the norcaradiene–cycloheptatriene equilibrium in a series of azulenones by NMR spectroscopy; the impact of substitution on the position of equilibrium'
Bateman, L. M.; McNamara, O. A.; Buckley, N. R.; O'Leary, P.; Harrington, F.; Kelly, N.; O'Keeffe, S.; Stack, A.; O'Neill, S.; McCarthy, D. G.; Maguire, A. R. (2015) 'A study of the norcaradiene–cycloheptatriene equilibrium in a series of azulenones by NMR spectroscopy; the impact of substitution on the position of equilibrium'. Organic and Biomolecular Chemistry, 13 :11026-11038 [DOI] [Details]
(2012)'Investigating the influence of the sulfur oxidation state on solid state'
Daly, Carla A.; Eccles, Kevin S.; Bateman, Lorraine M.; O'Boyle, Noel M.; Lawrence, Simon E.; Maguire, Anita R. (2012) 'Investigating the influence of the sulfur oxidation state on solid state'. CrystEngComm, 14 (23):7848-7850 Globe icon [CORA Link] [Details]
(2011)'Selective beta-oxidation of alpha-sulfanyl amides'
Kissane, Marie and Murphy, Maureen and Bateman, Lorraine M. and McCarthy, Daniel G. and Maguire, Anita R. (2011) 'Selective beta-oxidation of alpha-sulfanyl amides'. Tetrahedron, 67 (30):5494-5499 [DOI] [CORA Link] [Details]
(2008)'Recent advances in aryl–aryl bond formation by direct arylation'
Gerard P. McGlacken and Lorraine M. Bateman (2008) 'Recent advances in aryl–aryl bond formation by direct arylation'. Chemical Society Reviews, 38 :2447-2464 [DOI] [Details]
(2008)'New chiral diamide ligands: synthesis and application in allylic alkylation'
Lorraine Bateman, Simon W. Breeden†, Patrick O’Leary (2008) 'New chiral diamide ligands: synthesis and application in allylic alkylation'. Tetrahedron: Asymmetry, 19 (3):391-396 [DOI] [Details]

Conference Publications

YearPublication
(2015)SMASH NMR
Bateman, L. M., McNamara, O. A., Buckley, N. R., O'Leary, P., Harrington, F., Kelly, N., O'Keeffe, S., Stack, A., O'Neill, S., McCarthy, D. G. & Maguire, A. R. (2015) The norcaradiene-cycloheptatriene equilibrium in a series of azulenones by NMR spectroscopy; the impact of substitution on the position of equilibrium . In: SMASH NMR 2015 committee eds. SMASH NMR Baveno, Italy, [Details]
(2013)Conference on Analytical Sciences, Ireland (CASi)
Lorraine Bateman (2013) Development and Potential of Quantitative NMR Spectroscopy Conference on Analytical Sciences, Ireland (CASi) University College Cork, [Details]
(2010)239th ACS National Meeting
Gilheany, Declan G.; Bergin, Enda; Cumming, Graham R.; Dunne, Katherine S.; Granander, Johan; Kaik, Magdalena; Bateman, Lorraine; Kelly, Brian G.; King, Gary; Larichev, Vladimir (2010) Asymmetric catalytic hydrogenation using a library of DiPAMP analogs: Ligand tuning leads to dramatic improvements in selectivity and turnover 239th ACS National Meeting San Francisco, [Details]
(2010)239th ACS National Meeting, San Francisco, CA, United States, March 21-25, 2010
Gilheany, Declan G.; Bergin, Enda; Cumming, Graham R.; Dunne, Katherine S.; Granander, Johan; Kaik, Magdalena; Bateman, Lorraine; Kelly, Brian G.; King, Gary; Larichev, Vladimir; et a (2010) Asymmetric catalytic hydrogenation using a library of DiPAMP analogs: Ligand tuning leads to dramatic improvements in selectivity and turnover 239th ACS National Meeting, San Francisco, CA, United States, March 21-25, 2010 [Details]
(2007)15th European Symposium on Organic Chemistry
Gilheany, Declan G.; Bergin, Enda; Cumming, Graham R.; Dunne, Katherine S.; Granander, Johan; Kaik, Magdalena; Bateman, Lorraine; Kelly, Brian G.; King, Gary; Larichev, Vladimir (2007) Asymmetric hydrogenation using novel DiPAMP analogues 15th European Symposium on Organic Chemistry [Details]

Conference Contributions

YearPublication
(2016)NMR Discussion Group Spring Meeting: In Situ Monitoring by NMR: what is it all about? RSC NMR Discussion Group,
Bateman, L. M. (2016) Reaction monitoring by NMR discussion. [Visiting Critic], NMR Discussion Group Spring Meeting: In Situ Monitoring by NMR: what is it all about? RSC NMR Discussion Group, University of York . [Details]

Teaching Interests


Lecturer on:

  • PF2012 (Pharmaceutical Analysis)
  • PF4021 (Drug Design, Emerging Drugs and Mechanism of Action)
  • PF3016 (Pharmacognosy and Phytopharmaceuticals)
  • CM4022 (Advanced Organic Synthesis, Biosynthesis and Reactivity)
  • CM4108 (Advanced Pharmaceutical Chemistry)

Module Co-ordinator:

Teaching interests:
  • Nuclear Magnetic Resonance (NMR) Spectroscopy; Spectroscopy
  • Structural Analysis; Conformational Analysis
  • Equilibrating systems
  • Organic Synthesis; Asymmetric Synthesis
  • Analytical Chemistry; In situ reaction monitoring
  • Organic and Pharmaceutical Chemistry
  • Antiviral Agents
  • Biosynthesis of Natural Products