English
Follow UCC:
Prof John F Cryan BSc (Hons), PhD
Honours and Awards |
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| Year: 2007. Title: National Institutes for Mental Health, NIH, USA. Distinguished Lecturer |
| Year: 2006. Title: European College of Neuropsychopharmacology Fellowship Award |
| Year: 2006. Title: Wyeth Psychopharmacology Award of British Association of Psychopharmacology |
| Year: 2005. Title: Keynote speaker at New York Academy of the Sciences |
| Year: 2005. Title: Young Scientist Award from Foundation of the European Behavioural Pharmacology Society |
| Year: 2005. Title: Novartis Neuroscience Recognition Award |
Patents |
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| Patent WO/2011/058535 : Probiotic bifidobacterium strain |
| Patent WO 2004/071152 : Use of S-10 hydroxy-10, 11-dihydro-carbamazepine for the treatment of anxiety and bipolar disorders |
Conference Contributions |
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| O' Mahony SM, Clarke G, O' Mahony L, Quigley EMM, Cryan JF, Dinan TG (2007) Depressive behaviours and alterations in the immune and stress response systems following neonatal maternal separation. [Poster Presentation], European College of Neuropsychopharmacology (ECNP), 20th ECNP Congress, Vienna, Austria, September 2007, Vienna , 13-OCT-07 - 17-OCT-07. |
| Clarke G, Fitzgerald P, Cassidy E, Cryan JF, Quigley EM, Dinan TG (2008) Increased tryptophan degradation along the kynurenine pathway in Irritable Bowel Syndrome (IBS)-Evidence of an immune mediated indoleamine 2,3-dioxygenase (IDO) activation in a male cohort. [Poster Presentation], Irish Society of Gastroenterology, Sligo, Ireland, April 2008, Sligo , 24-APR-08 - 25-APR-08. |
| Fitzgerald P, Clarke G, Scully P, Cryan JF, Shanahan F, Quigley EMM, Cassidy EM, Dinan TG (2008) Tryptophan catabolism in irritable bowel syndrome: Relationship to cytokines, severity and psychiatric comorbidity. [Poster Presentation], Digestive Disease Week, San Diego, USA, May 2008, San Diego , 17-MAY-08 - 22-MAY-08. |
| Clarke G, Fitzgerald P, Cryan JF, Cassidy EM,Quigley EMM, Dinan TG (2008) Altered kynurenine pathway metabolism in Irritable Bowel Syndrome (IBS)-Evidence of indoleamine 2,3-dioxygenase (IDO) activation in a male cohort. [Poster Presentation], Digestive Disease Week, San Diego, USA, May 2008, San Diego , 17-MAY-08 - 22-MAY-08. |
| Clarke G, O’Mahony SM, Hyland, NP, Fitzgerald P, Cryan JF, Dinan TG (2008) Beta3 adrenoceptor modulation of visceral pain-a possible role for the kynurenine pathway?. [Poster Presentation], European Behavioural Pharmacology Society Workshop on Behavioural Genetics and Neuropsychiatric Disorders, Cork, Ireland, September 2008, Cork , 25-AUG-08 - 27-AUG-08. |
| Clarke G, Fitzgerald P, Cryan JF, Dinan TG. (2008) Increased tryptophan metabolism in irritable bowel syndrome (IBS)–an immune mediated phenomenon?. [Poster Presentation], Second Joint International Meeting for Neurogastroenterology and Motility, Lucerne, Switzerland, November 2008, Lucerne , 06-NOV-08 - 09-NOV-08. |
| Clarke G, O’Mahony SM, Hyland NP, Fitzgerald P, Dinan TG, Cryan JF (2008) Visceral pain and beta3 adrenoceptor modulation: a role for the kynurenine pathway?. [Poster Presentation], Second Joint International Meeting for Neurogastroenterology and Motility, Lucerne, Switzerland, November 2008, Lucerne , 06-NOV-08 - 09-NOV-08. |
| Clarke, G, O'Mahony, S, Hyland, NP, Fitzgerald, P, Dinan, TG, Cryan, JF; (2008) Beta3 Adrenoceptor Modulation of Visceral Pain - A Possible Role For The Kynurenine Pathway?, . |
| Clarke G, Fitzgerald P, Cryan JF, Cassidy EM,Quigley EMM, Dinan TG (2008) Tryptophan Degradation and Irritable Bowel Syndrome (IBS)-Evidence of an immune mediated indoleamine-2,3-dioxygenase (IDO) activation in a male cohort. [Poster Presentation], International Neuroimmunology Symposium, University College Dublin, Dublin, Ireland, March 2008, Dublin , 13-MAR-08 - 14-MAR-08. |
| Browne CA, Clarke, G, Dinan TG, Cryan JF. (2009) Behavioural effects of dietary trypotphan manipulations on c57bl/6j and balb/c mice. [Poster Presentation], Neuroscience Ireland, Trinity College Dublin, September 2009, Dublin , 10-SEP-09 - 11-SEP-09. |
| Clarke G, Fitzgerald P, Hennessy AA, Cassidy EM, Quigley EMM, Ross P, Stanton C, Cryan JF, Dinan TG (2009) Polyunsaturated fatty acids contribute to the inflammatory phenotype in irritable bowel syndrome. [Poster Presentation], Digestive Disease Week, Chicago, USA, June 2009, Chicago , 31-MAY-09 - 03-JUN-09. |
| Browne CA, Clarke G., Dinan TG, Cryan JF (2009) Restraint stress alters tryptophan hydroxylase 2 activity in BALB/c mice: relevance to depression. [Poster Presentation], European College of Neuropsychopharmacology, Workshop on Neuropsychopharmacology for Young Scientists in Europe, Nice, France, March 2009, Nice , 05-MAR-09 - 08-MAR-09. |
| Clarke G, O'Mahony SM, Hennessy AA, Ross P, Stanton C, Cryan JF, Dinan TG (2009) Chain reactions: Polyunsaturated fatty acids and the depressive phenotype in maternally separated rodents. [Poster Presentation], European College of Neuropsychopharmacology, Istanbul, Turkey, September 2009, Istanbul , 12-SEP-09 - 16-SEP-09. |
| Julio M, O’Mahony C, Clarke G, Bravo J, Dinan TG, Cryan JF (2010) Strain-specific alterations in colon 5-HT levels correlate to defecation responses in chronically stressed mice. [Poster Presentation], 7th World Congress on Stress, Leiden, Holland, August 2010, Leiden , 25-AUG-12 - 27-AUG-12. |
| Scully P, Clarke G, Grenham S, Fitzgerald P, O’Mahony CM, ,McKernan DP,Tramullas M,Shanahan F, Dinan TG, & Cryan JF (2010) Gender-Dependent Influence of the Gut Microbiome on the Hippocampal 5-HT System. [Poster Presentation], Psychoneuroimmunology Research Society, Trinity College, Dublin, June 2010, Dublin , 02-JUN-10 - 05-JUN-10. |
| Scully P, Clarke G, Grenham S, Fitzgerald P, O’Mahony CM,McKernan DP,Tramullas M,Shanahan F, Dinan TG, & Cryan JF (2010) Gender-Dependent Influence of the Gut Microbiome on the Hippocampal 5-HT System. [Poster Presentation], Health and Medicine Research Day, Brookfield, Cork, June 2010, Cork , 16-JUN-10 - 16-JUN-10. |
| Cryan JF, Clarke G, Grenham S, Scully P, Shanahan F, Dinan TG (2010) The gut microbiome markedly influences hippocampal neurotransmission in the mouse: Role of gender. [Poster Presentation], Society for Neuroscience, San Diego, USA, November 2010, San Diego , 13-NOV-10 - 17-NOV-10. |
| Tramullas M, Clarke G, Shanahan F, Dinan TG, Cryan JF (2010) The gut microbiome alters toll-like receptor and cytokine expression levels in the spinal cord: Role of gender. [Poster Presentation], Society for Neuroscience, San Diego, USA, November 2010, San Diego , 13-NOV-10 - 17-NOV-10. |
| O’Brien FE, Clarke G, Fitzgerald P, Griffin BT, Cryan JF (2011) An integrated microdialysis model for the analysis of blood-brain barrier drug transport in the conscious freely moving rat. [Poster Presentation], College of Medicine and Health Research Day, UCC, June 2011, Cork , 22-JUN-11 - 22-JUN-11. |
| Clarke G, Grenham S, Scully P, Fitzgerald P, Moloney, RD, Shanahan F, Dinan TG, Cryan JF (2012) Regulation of Serotonergic Neurotransmission and Behaviour by the Brain-Gut-Microbiome Axis. [Poster Presentation], Digestive Disease Week, San Diego, USA, May 2012, San Diego , 19-MAY-12 - 22-MAY-12. |
| Kennedy PJ, Clarke G, O’Neill A, Groeger JA, Quigley EM, Shanahan F , Cryan JF, Dinan TG (2012) Are deficits in episodic memory stress-related and mediated by tryptophan metabolism along the kynurenine pathway?. [Poster Presentation], Digestive Disease Week, San Diego, USA, May 2012, San Diego , 19-MAY-12 - 22-MAY-12. |
| Cryan, J. F.; (2008) From Mouse to Man: Behavioural Genetics and its Relevance to Psychiatric Disorders. [Conference Organising Committee Member], European Behavioural Pharmacology Society Meeting, Cork, Ireland , 01-JAN-08 - 01-JAN-08. |
| Cryan, J. F.; (2008) Corticolimbic dysfunction in stress-related disorders: From mouse to man, from molecule to medicine. [Conference Organising Committee Member], XXVIth Congress of the Collegium Internationale Neuro-Psychopharmacologium, Munich, Germany , 01-JUL-08 - 01-JUL-08. |
| Cryan, J. F.; (2008) New insights into Cortico-Amygdala interactions: implications for disorders of emotion. [Conference Organising Committee Member], FENS Meeting, Geneva, Switzerland , 01-JUL-08 - 01-JUL-08. |
| Cryan, J. F.; (2007) Genetic Approaches to Study Depression and the Antidepressant response. [Conference Organising Committee Member], Ninth Annual Meeting of the International Behavioural and Neural Genetics Society, Doorwerth, The Netherlands , 21-MAY-07 - 25-MAY-07. |
| L. Lhuillier, C. Mombereau, J.F. Cryan, K. Kaupmann; (2006) The GABAB receptor positive allosteric modulator GS39783 attenuates selected molecular markers and behavioral effects relevant to both cocaine and nicotine dependence. [Poster Presentation], Young Scientist Workshop of the European College of Neuropsychopharmacology, Nice, France , 01-MAR-06 - 01-MAR-06. |
| Cryan, J. F.; (2006) Recent advances in understanding the neural substrates of anxiety using rodent models. [Conference Organising Committee Member], XXVth Congress of the Collegium Internationale Neuro-Psychopharmacologium, Chicago , 01-JUL-06 - 01-JUL-06. |
| C. Mombereau, L.C. Lhuillier, K. Kaupmann, J.F. Cryan; (2005) The GABAB Receptor-Positive Modulator GS39783 blocks the acquisition of nicotine place preference in the rat. [Poster Presentation], The Society for Neuroscience 35th Annual Meeting, Washington, USA , 01-NOV-05 - 01-NOV-05. |
| D.A. Slattery, A. Markou, W. Froestl, J.F. Cryan; (2005) The GABAB receptor-positive modulator GS39783 and the GABAB receptor agonist baclofen attenuate the reward-facilitating effects of cocaine: intracranial self-stimulation studies in the rat. [Poster Presentation], The Society for Neuroscience 35th Annual Meeting, Washington, USA , 01-NOV-05 - 01-NOV-05. |
| P.J. Flor, K. Mitsukawa, C. Mombereau, E. Ltscher, D.P. Uzunov, H. van der Putten, J.F. Cryan; (2005) Metabotropic glutamate receptor subtype 7 ablation causes dysregulation of the HPA axis and increases hippocampal BDNF protein levels: implications for stress-related psychiatric disorders. [Poster Presentation], The Society for Neuroscience 35th Annual Meeting, Washington, USA , 01-NOV-05 - 01-NOV-05. |
| Mitsukawa, R. Yamamoto, J. Nozulak, S. Ofner, O. Pescott, S. Lukic, N. Stoehr, S. Urwyler, R. Kuhn, P. Herrling, J.F. Cryan, P.J. Flor; (2005) AMN082, the first selective metabotropic glutamate receptor subtype 7 agonist: activation of receptor signaling via an allosteric site in the transmembrane domain. [Poster Presentation], The Society for Neuroscience 35th Annual Meeting, Washington, USA , 01-NOV-05 - 01-NOV-05. |
| L.H. Jacobson, K. Kaupmann, B. Bettler, J.F. Cryan; (2005) differential influence of GABAB(1) receptor subunit isoforms on baseline but not GABAB agonist-induced behavioural changes in mice. [Poster Presentation], The Society for Neuroscience 35th Annual Meeting, Washington, USA , 01-NOV-05 - 01-NOV-05. |
| D.A. Slattery, C. Mombereau, W. Froestl, A. Markou, K. Kaupmann, and Cryan, J.F; (2005) GABAB receptor positive modulation as a novel therapeutic approach to drug dependence: Blockade of the rewarding and psychostimulant effects of cocaine. [Poster Presentation], Young Scientist Workshop of the European College of Neuropsychopharmacology, Nice, France , 01-MAR-05 - 01-MAR-05. |
| D.R. Thakker, F. Natt, D. Hüsken, M. Mller, R. Maier, H. van der Putten, D. Hoyer, Cryan, J.F.; (2005) Behavioural and neurochemical consequences of siRNA-induced knockdown of serotonin and dopamine transporters in the adult mouse brain: Implications for validation of novel therapeutic targets for psychiatric illnesses. [Poster Presentation], Experimental Biology Meeting, San Diego, USA , 01-APR-05 - 01-APR-05. |
| A. Markou; N.E. Paterson; P.J. Kenny; S. Semenova; J.F.Cryan; (2005) Measuring anhedonia in animals: Reversal by Antidepressant Treatments. [Poster Presentation], The American College of Neuropsychopharmacology 44th Annual Meeting, Hawaii , 01-DEC-05 - 01-DEC-05. |
| Cryan, J. F.; (2005) ETH Zurich on Neurogenetics and Behaviour. [Conference Organising Committee Member], European Brain and Behaviour Society, Dublin, Ireland , 01-SEP-05 - 01-SEP-05. |
| Kaupmann, K., Cryan, J.F., Wellendorph, P. Mombereau, C. Sansig, G. Klebs, K., Schmutz, M., Froestl, W. van der Putten, H., Mosbacher, J., Bräuner-Osborne, H., Waldmeier, P., and Bettler, B.; (2003) Effects of g-hydroxybutyrate in GABA-B receptor deficient mice. [Poster Presentation], The Society for Neuroscience 33rd Annual Meeting, New Orleans, USA , 01-NOV-03 - 01-NOV-03. |
| Cryan, J.F. , Szeliga, P.J., Gasparini, F. Page. M.E.; (2003) Potential anxiolytic-like actions of metabotropic glutamate receptor 5 (mGluR5) antagonists revealed by neurochemical and behavioral studies. [Poster Presentation], The Society for Neuroscience 33rd Annual Meeting, New Orleans, USA , 01-NOV-03 - 01-NOV-03. |
| Cryan, J.F. Kelly, P.H. Sansig, G., Flor P.J. and van Der Putten, H.; (2003) Antidepressant and anxiolytic-like effects in mice lacking the group III metabotropic glutamate receptor mGluR7 `03 E. [Poster Presentation], Experimental Biology Meeting, San Diego, USA , 01-APR-03 - 01-APR-03. |
| Cryan, J. F. ; (2008) unknown. [Oral Presentation], In search of a depressed mouse: Genetic and behavioural approaches to understand the pathophysiology of depression, University of Newcastle, UK , 01-OCT-08 - 01-OCT-08. |
| Cryan, J. F. ; (2008) Stress and the Brain-Gut Axis: From the Bowel to Behaviour. [Oral Presentation], Unknown, MacMaster University, Hamilton, Canada , 01-SEP-08 - 01-SEP-08. |
| Clarke G, Fitzgerald P, Cassidy E, Cryan JF, Quigley EM, Dinan TG; (2008) Increased tryptophan degradation along the kynurenine pathway in Irritable Bowel Syndrome (IBS)-Evidence of an immune mediated indoleamine 2,3-dioxygenase (IDO) activation in a male cohort. [Poster Presentation], Irish Society of Gastroenterology Spring Conference, Sligo, Ireland , 01-APR-08 - 01-APR-08. |
| Hyland NP, O¿Mahony SM, Bulmer DC, Lee K, Dinan TG & Cryan JF; (2008) Do mast cells contribute to visceral hypersensitivity in adult rats following neonatal psychological stress?. [Poster Presentation], Irish Society of Gastroenterology Spring Conference, Sligo, Ireland , 01-APR-08 - 01-APR-08. |
| Gibney SM, Gosselin RD, O¿Malley DM, Dinan TG & Cryan JF; (2008) Imaging distinct patterns of cortical brain activation following colorectal distension in an animal model of Irritable Bowel Syndrome. [Poster Presentation], Irish Society of Gastroenterology Spring Conference, Sligo, Ireland , 01-JAN-08 - 01-JAN-08. |
| Bravo JA, Dinan TG & Cryan JF; (2008) The effects of the acetylcholinesterase inhibitor pyridostigmine on inflammatory responses in an animal model of irritable bowel syndrome. [Poster Presentation], International neuroimmunology symposium, UCD, Dublin, Ireland , 01-MAR-08 - 01-MAR-08. |
| Clarke G, Fitzgerald P, Cassidy E, Cryan JF, Quigley EM, Dinan TG; (2008) Altered kynurenine pathway metabolism in Irritable Bowel Syndrome (IBS)-Evidence of indoleamine 2,3-dioxygenase (IDO) activation in a male cohort. [Poster Presentation], Digestive Disease Week, San Diego, USA , 01-MAY-08 - 01-MAY-08. |
| Bulmer DC, O' Mahony, SM, Coelho A-M, Gray K, Taylor CM, Dinan TG, Cryan JF, Lee K, Winchester WJ; (2008) Analgesic effects of 5-HT2B antagonists in pre-clinical models of colorectal pain. [Poster Presentation], Digestive Disease Week, San Diego, USA , 01-JAN-08 - 01-JAN-08. |
| Coelho AM, O 'Mahony SM, Taylor CM, Wheeldon A, Fitzgerald P, Dinan T, Cryan JF, Lee K, Winchester WJ.; (2008) Gabapentin reverses colorectal distension-induced visceral pain behaviours in rat models of acute and chronic visceral hypersensitivity. [Poster Presentation], Digestive Disease Week, San Diego, USA , 01-JAN-08 - 01-JAN-08. |
| Hyland NP, O¿Mahony SM, Bulmer DC, Lee K, Dinan TG & Cryan JF; (2008) Do mast cells contribute to visceral hypersensitivity in adult rats following neonatal psychological stress?. [Poster Presentation], Digestive Disease Week, San Diego, USA , 01-JAN-08 - 01-JAN-08. |
| Hyland NP, Gibney SM, Gosselin RD, Lee K, Dinan TG & Cryan JF; (2008) Assessment of colonic secretory function and faecal output in viscerally hypersensitive Wistar Kyoto rats. [Poster Presentation], Digestive Disease Week, San Diego, USA , 01-JAN-08 - 01-JAN-08. |
| Savignac HM, Hyland NP, Dinan TG & Cryan JF ; (2008) Social stress induces mild colonic damage and altered anti-inflammatory cytokines in the mouse. [Poster Presentation], All Ireland Schools of Pharmacy Research Conference, Cork, Ireland , 01-APR-08 - 01-APR-08. |
| O¿ Mahony Cliona M, Bravo J, Dinan TG, Cryan JF; (2008) Comparison of stress-induced alterations in hippocampal mGluR7 mRNA in two animal models of depression. [Poster Presentation], British Association for psychoparmacology, Summer meeting, Harrogate, UK , 01-JUL-08 - 01-JUL-08. |
| Fendt, M., Schmid, S., Thakker, D.R., Jacobson, L.H., Yamamota, R. Mitsukawa, K. Maier, R, McAllister, K.H., Hoyer, D. van der Putten, H. Cryan JF and Flor, P.J; (2008) Control of stress- and anxiety- related physiology and behavior by mGluR7 modulation. [Poster Presentation], 6th Meeting on Metabotropic Glutamate receptors, Taormina, Sicily Italy , 01-SEP-08 - 01-SEP-08. |
| Clarke G, O'Mahony S, Hyland NP, Dinan TG & Cryan JF; (2008) Beta3 adrenoceptor modulation of visceral pain - A possible role for the kynurenine pathway?. [Poster Presentation], European-Behavioural-Pharmacology-Society Workshop on Behavioural Genetics and Neuropsychiatric Disorders, Cork, Ireland , 01-AUG-08 - 01-AUG-08. |
| Cryan, J. F. ; (2008) Genetic and Pharmacological Tools to Unravel the Role of mGluR7 in Stress-related Behavioural Disorders. [Oral Presentation], Unknown, Samuel Lunenfeld Research Center, Mt Sinai Hospital, Univ. Toronto, Canada , 01-SEP-08 - 01-SEP-08. |
| Cryan, J. F. ; (2008) In vivo Genetic Approaches to Aid in Development of Novel Therapeutic Targets for Stress-related Disorders: Focus on mGluR7. [Oral Presentation], Unknown, Helmholz Zentrum Muenchen, Institute of Developmental Genetics, Munich , 01-JUL-08 - 01-JUL-08. |
| Cryan, J. F. ; (2008) In vivo Genetic Approaches to Understand the Role of mGluR7 in Stress-Related Disorders. [Oral Presentation], Unknown, Ruhr Univ. Bochum, Germany , 01-JUL-08 - 01-JUL-08. |
| Cryan, J. F. ; (2008) Silencing the Unquiet Mind: Knockout and RNA Interference-based approaches to Understand Depression and Anxiety. [Oral Presentation], Unknown, Univ Oxford, Dept Pharmacology, UK , 01-JUN-08 - 01-JUN-08. |
| Cryan, J. F. ; (2008) Silencing the Unquiet Mind: Knockout and RNA Interference-based approaches to Understand Depression and Anxiety. [Oral Presentation], Unknown, Univ. California San Diego , 01-JUN-08 - 01-JUN-08. |
| Cryan, J. F. ; (2008) Silencing the Unquiet Mind: Knockout and RNA Interference-based approaches to Understand Depression and Anxiety. [Oral Presentation], Unknown, Univ. Liverpool, UK , 01-APR-08 - 01-APR-08. |
| Cryan, J. F. ; (2008) Silencing the Unquiet Mind: Knockout and RNA Interference-based approaches to Understand Depression and Anxiety. [Oral Presentation], Unknown, Boerhinger Ingelheim, Biberach, Germany, , 01-FEB-08 - 01-FEB-08. |
| Cryan, J. F.; (2008) Novel pharmacological and genetic tools to unravel GABA-Glutamate imbalance in anxiety. [Invited Oral Presentation], XVIII Asociación Latino- Americana de Farmacología Congress, Coquimbo, Chile , 01-OCT-08 - 01-OCT-08. |
| Cryan, J. F.; (2008) Genetic and pharmacological tools to unravel the role of mGluR7 in stress-related disorders. [Invited Oral Presentation], XXVIth Congress of the Collegium Internationale Neuro-Psychopharmacologium, Chicago , 01-JUL-08 - 01-JUL-08. |
| Hyland NP, O¿Mahony SM, Bongiovanni C, Julio-Pieper, M, Bulmer DC, Dinan TG, Cryan JF; (2008) Beta3-adrenoceptor mediated secretion and localisation in the submucosal plexus of descending colon from maternally separated animals. [Poster Presentation], Meeting for Neurogastroenterology and Motility Second Joint International M, Lucerne, Switzerland , 01-NOV-08 - 01-NOV-08. |
| Clarke G., Fitzgerald P, Cryan JF, Dinan TG; (2008) Increased tryptophan metabolism in irritable bowel syndrome (IBS)¿an immune mediated phenomenon?. [Poster Presentation], Second Joint International Meeting for Neurogastroenterology and Motility,, Lucerne, Switzerland , 01-NOV-08 - 01-NOV-08. |
| Gibney SM, Gosselin RD, O¿Malley D, Dinan TG & Cryan JF; (2008) Altered colonic rectal distension-induced activation of the prefrontal cortex in two animals models of irritable bowel syndrome (IBS). [Poster Presentation], Second Joint International Meeting for Neurogastroenterology and Motility, Lucerne, Switzerland , 01-NOV-08 - 01-NOV-08. |
| Hyland NP, O¿Callaghan K., O¿Malley D, Dinan TG & Cryan JF; (2008) Differential cholinergic sensitivity in the enteric nervous system in two models of visceral hypersensitivity. [Poster Presentation], Second Joint International Meeting for Neurogastroenterology and Motility,, Lucerne, Switzerland , 01-NOV-08 - 01-NOV-08. |
| O¿Mahony SM, Fitzgerald P, Bulmer DC, Coelho AM, Dinan TG & Cryan JF; (2008) Central 5-HT2B receptors modulate visceral hypersensitivity in a genetic model of irritable bowel syndrome. [Poster Presentation], Second Joint International Meeting for Neurogastroenterology and Motility, Lucerne, Switzerland , 01-NOV-08 - 01-NOV-08. |
| O¿Malley D, Julio-Pieper M, Dinan TG & Cryan JF; (2008) The effects of stress on colonic morphology in two animal models of irritable bowel syndrome. [Poster Presentation], Second Joint International Meeting for Neurogastroenterology and Motility, Lucerne, Switzerland , 01-NOV-08 - 01-NOV-08. |
| O¿Malley D, Julio-Pieper M, Dinan TG & Cryan JF; (2008) CRF receptor expression in the brain and colon of WKY rats following colorectal distension. [Poster Presentation], Second Joint International Meeting for Neurogastroenterology and Motility, Lucerne, Switzerland , 01-NOV-08 - 01-NOV-08. |
| Gosselin RD, Gibney S, O'Malley D, Dinan TG & Cryan JF; (2008) Region specific decrease in glial fibrillary acidic protein (GFAP) immunoreactivity in the brain of a genetic rat model of depression. [Poster Presentation], European-Behavioural-Pharmacology-Society Workshop on Behavioural Genetics and Neuropsychiatric Disorders, Cork, Ireland , 01-AUG-08 - 01-AUG-08. |
| Hyland NP, Dinan TG, Cryan JF; (2007) Stress susceptible Wistar Kyoto rats display altered epithelial cholinergic sensitivity in the distal colon. [Poster Presentation], Irish Society of Gastroenterology, Winter Meeting, Dublin, Ireland , 01-DEC-07 - 01-DEC-07. |
| Clarke G, Barry S, Scully P, Cryan JF, Dinan T; (2007) Simultaneous measurement of tryptophan and it¿s kynurenine pathway metabolites by HPLC: evidence of increased tryptophan degradation in psychosis. [Poster Presentation], European Graduate School of Neuroscience workshop, Bad Honnef, Germany , 01-NOV-07 - 01-NOV-07. |
| Cryan, J. F. ; (2007) Using novel genetic and pharmacological tools to unravel the role of GABAB receptors in anxiety, depression and drug abuse. [Oral Presentation], Unknown, Univ. Birmingham, UK , 01-FEB-07 - 01-FEB-07. |
| Cryan, J. F. ; (2007) GABAB receptors Play a Key Role in Neuropsychiatric Disorders: Recent Developments with Novel Genetic and Pharmacological Tools. [Oral Presentation], Unknown, Univ. Copenhagen, Denmark , 01-MAR-07 - 01-MAR-07. |
| Cryan, J. F. ; (2007) Silencing the Unquiet Mind: Knockout and RNA Interference-based approaches to Understand Depression and Anxiety. [Oral Presentation], Unknown, National Institute of Health, Bethesda USA, Mood and Anxiety Disorders Program Distinguished Lecturer , 01-APR-07 - 01-APR-07. |
| Cryan, J. F. ; (2007) Silencing the Unquiet Mind: Knockout and RNA Interference-based Approaches to Understand Depression and Anxiety. [Oral Presentation], Unknown, Sepracor Corp, Marlborough MA, USA, , 01-AUG-07 - 01-AUG-07. |
| O' Mahony SM, Clarke G, O' Mahony L, Quigley EMM, Cryan JF, Dinan TG; (2007) Depressive behaviours and alterations in the immune and stress response systems following neonatal maternal separation. [Poster Presentation], 19th congress of the European College of Neuropharmacology, Vienna, Austria , 01-JAN-07 - 01-JAN-07. |
| Clarke G, Cryan JF, Dinan TG; (2007) An important subplot in the inflammatory theory of depression?. [Poster Presentation], Brainstorming session, 20th Congress of European College of Neuropsychopharmacology, Vienna, Austria , 01-OCT-07 - 01-OCT-07. |
| O' Mahony SM, Fitzgerald P, Coehlo A-M, Taylor C, Cryan JF, Dinan TG.; (2007) Visceral hypersensitivity in two potential animal models of Irritable Bowel Syndrome. [Poster Presentation], The College of Medicine & Health, UCC Joint Health Research Day incorporating Cork University Hospital Research Day, Cork, Ireland , 01-JAN-07 - 01-JAN-07. |
| Savignac HM, Hyland NP, Dinan TG, Cryan JF ; (2007) Social stress induces mild colonic damage and altered pro- and anti-inflammatory cytokines in the mouse. [Poster Presentation], The Irish Society of Gastroenterology Winter meeting, Clontarf Castle Hotel, Dublin, Ireland , 01-NOV-07 - 01-NOV-07. |
| Cryan, J. F.; (2007) Novel therapeutic targets for stress-related disorders. [Invited Oral Presentation], British Neuroscience Association Annual Meeting, Harrogate, UK , 01-APR-07 - 01-APR-07. |
| Cryan, J. F.; (2007) In search of depressed mouse: Using genetically modified mice to understand depression. [Invited Oral Presentation], Unknown, Doorwerth, The Netherlands , 01-MAY-07 - 01-MAY-07. |
| Cryan, J. F.; (2007) Anatomy of emotion: Corticolimbic modulation of depression and anxiety-related behaviour in animal models. [Invited Oral Presentation], Royal Academy of Medicine in Ireland, Summer Meeting, Cork, Ireland , 01-JUN-07 - 01-JUN-07. |
| Browne, CA, O¿Brien, F, Connor TJ, Dinan, TG, & Cryan JF; (2007) Differential LPS-induced cytokine responses in C57BL/6J and BALB/c mice following stress: Relevance to depression. [Poster Presentation], European Graduate School of Neuroscience (EURON), Bad Honnef, Germany , 01-NOV-07 - 01-NOV-07. |
| Cryan, J. F. ; (2006) Silencing the Unquiet Mind: The Emerging use of RNAi to Understand the Pathophysiology of Neuropsychiatric Disorders. [Oral Presentation], Unknown, Solvay Duphar, Weesp, The Netherlands , 01-OCT-06 - 01-OCT-06. |
| Cryan, J. F. ; (2006) Silencing the Unquiet Mind: The Emerging use of RNAi in Preclinical Neuropsychiatric Research. [Oral Presentation], Uncle Tom's Cabin and the Irish National Tale, International Symposium RNAi in vivo Technologies¿, Munich, Germany , 01-OCT-06 - 01-OCT-06. |
| Cryan, J. F. ; (2006) Silencing the Unquiet Mind: The Emerging use of RNAi to Understand the Pathophysiology of Neuropsychiatric Disorders. [Oral Presentation], Unknown, Johnson and Johnson, Beerse, Belgium , 01-SEP-06 - 01-SEP-06. |
| Cryan, J. F.; (2006) Genetic and behavioural approaches to understand the pathophysiology of depression. [Oral Presentation], Unknown, European Science Foundation (ESF) Workshop on Links between Visceral Dysfunction and Affective Disorders, Graz, Austria , 01-AUG-06 - 01-AUG-06. |
| Cryan, J. F.; (2006) In vivo Genetic Approaches to Understand the Role of mGluR7 in Brain Function. [Oral Presentation], Unknown, Wyeth Pharma, Princeton New Jersey, USA , 01-JUL-06 - 01-JUL-06. |
| Cryan, J. F.; (2006) Mouse models of psychiatric illness. [Oral Presentation], Unknown, Hi Q Workshop on Assessing Cognition in Animal Models of Huntington Disease, Cambridge, UK , 01-JUL-06 - 01-JUL-06. |
| Cryan, J. F.; (2006) Silencing the Unquiet Mind: The Emerging use of RNAi to understand the pathophysiology of neurological and psychiatric disorders. [Oral Presentation], Unknown, Roche Pharma AG, Basel, Switzerland , 01-MAR-06 - 01-MAR-06. |
| Cryan, J. F.; (2006) Modifying Mood: From molecule to mouse to man- A personal perspective on neuropharmacological research in industry and academia. [Oral Presentation], Unknown, Galway-Mayo Institute of Technology, Galway, Ireland , 01-JAN-06 - 01-JAN-06. |
| Cryan, J. F.; (2006) Anxiety viewed as a GABA-ergic and glutamatergic disbalance, perspectives for development of new anxiolytic drugs. [Invited Oral Presentation], European College of Neuropsychopharmacology, Paris , 01-SEP-06 - 01-SEP-06. |
| Cryan, J. F.; (2006) Widespread gene knockdown in the adult brain using RNA Interference. [Invited Oral Presentation], Neuroscience Ireland Inaugural meeting, Cork, Ireland , 01-SEP-06 - 01-SEP-06. |
| Cryan, J. F.; (2006) Academia-Industry Interactions in Neuropsychopharmacology Research. [Invited Oral Presentation], XXVth Congress of the Collegium Internationale Neuro-Psychopharmacologium, Chicago , 01-JUL-06 - 01-JUL-06. |
| O¿ Mahony Cliona, Daly E, Dinan TG, Cryan JF.; (2006) Genetic influence on stress-induced changes in brain activation in the mouse. [Poster Presentation], Neuroscience Ireland inaugural conference, Cork, Ireland , 01-SEP-06 - 01-SEP-06. |
| Bissiere, S., Plachta, N., McAllister, K., Hoyer, D., Olpe, HR, Grace, AA, Cryan, JF; (2006) The rostral anterior cingulate cortex determines the efficiency of amygdala-dependent fear learning. [Poster Presentation], Program No. 67.26. 2006 Neuroscience Meeting Planner, Atlanta, Georgia , 01-JAN-06 - 01-JAN-06. |
| Jacobson LH, Kaupmann, K., Bettler., Cryan JF; (2006) GABAB(1) receptor subunit isoforms: A role in anxiety?. [Poster Presentation], Program No. 72.17. 2006 Neuroscience Meeting Planner, Atlanta, Georgia , 01-JAN-06 - 01-JAN-06. |
| Jacobson LH, Kaupmann, K., Bettler., Cryan JF; (2006) The GABAB(1a) receptor subunit isoform mediates antidepressant-like effects: role of 5-HT1A receptors. [Poster Presentation], Program No. 72.18. 2006 Neuroscience Meeting Planner. Atlanta, GA: Society for Neuroscience, Atlanta, Georgia , 01-JAN-06 - 01-JAN-06. |
| Fendt, M., Schmid, S., Thakker, D.R., Jacobson, L.H., Yamamota, R. Mitsukawa, K. Maier, R, McAllister, K.H., Hoyer, D. van der Putten, H. Cryan JF and Flor, P.J; (2006) Activation of mGluR7 alters amygdala plasticity and facilitates extinction of fear memories. [Poster Presentation], Program No. 370.15. 2006 Neuroscience Meeting Planner, Atlanta, Georgia , 01-JAN-06 - 01-JAN-06. |
| O¿ Mahony Cliona, Daly E, Dinan TG, Cryan JF; (2006) Genetic influence on stress-induced changes in brain activation in the mouse. [Poster Presentation], 2nd Interdisciplinary research day of the college of medicine and health, University College Cork, Ireland , 01-NOV-06 - 01-NOV-06. |
| Slattery DA, Markou A, Cryan JF; (2006) Evaluation of reward processes in an animal model of depression. [Poster Presentation], 19th Congress of European College of Neuropsychopharmacology, Paris , 01-SEP-06 - 01-SEP-06. |
| Slattery DA, Markou A, Cryan JF; (2006) Evaluation of reward processes in an animal model of depression. [Poster Presentation], XXVth Congress of the Collegium Internationale Neuro-Psychopharmacologium, Chicago , 01-JUL-06 - 01-JUL-06. |
| Cryan J.F.; (2005) Interfering with the brain : The use of siRNA to understand the roles of genes in neuropsychiatric. [Invited Lectures (Conference)], Interfering with the brain : The use of siRNA to understand the roles of genes in neuropsychiatric, . |
| Cryan J.F.; (2005) Interfering with Brain Function: Emerging use of siRNA to unravel the roles of genes in psychiatric and neurological disorders. [Invited Lectures (Conference)], Interfering with Brain Function: Emerging use of siRNA to unravel the roles of genes in psychiatric and neurological disorders, . |
| Cryan, J. F.; (2005) Interfering with Brain Function: Emerging use of siRNA to understand the roles of genes in psychiatric disorders. [Oral Presentation], Unknown, University of Innsbruck, Department of Pharmacology and Toxicology, Austria , 01-JAN-05 - 01-JAN-05. |
| Cryan, J. F.; (2005) Interfering with the brain : The use of siRNA to understand the roles of genes in neuropsychiatric disorders. [Oral Presentation], Unknown, Rockefeller University, New York, USA , 01-NOV-05 - 01-NOV-05. |
| Cryan J.F.; (2005) A role for GABAB receptors in anxiety, depression and drug abuse: Recent developments with novel genetic and pharmacological tools. [Invited Lectures (Conference)], A role for GABAB receptors in anxiety, depression and drug abuse: Recent developments with novel genetic and pharmacological tools, . |
| Cryan J.F.; (2005) A role for GABAB receptors in anxiety, depression and drug abuse: Recent developments with novel genetic and pharmacological tools. [Invited Lectures (Conference)], A role for GABAB receptors in anxiety, depression and drug abuse: Recent developments with novel genetic and pharmacological tools, . |
| Cryan J.F.; (2005) Interfering with Brain Function: Emerging use of siRNA to understand the roles of genes in psychiatric and neurological disorders. [Invited Lectures (Conference)], Interfering with Brain Function: Emerging use of siRNA to understand the roles of genes in psychiatric and neurological disorders, . |
| Cryan J.F.; (2005) siRNA-Induced Widespread Gene Knockdown in the Adult Mouse Brain: Utility for studying the molecular basis of neuropsychiatric disorders. [Invited Lectures (Conference)], siRNA-Induced Widespread Gene Knockdown in the Adult Mouse Brain: Utility for studying the molecular basis of neuropsychiatric disorders, . |
| Cryan J.F.; (2005) Interfering with Brain Function: Emerging use of siRNA to understand the roles of genes in psychiatric disorders. [Invited Lectures (Conference)], Interfering with Brain Function: Emerging use of siRNA to understand the roles of genes in psychiatric disorders, . |
| Cryan, J. F.; (2005) mGluR7: A novel therapeutic target for stress-related disorders. [Invited Oral Presentation], The American College of Neuropsychopharmacology 44th Annual Meeting, Hawaii , 01-DEC-05 - 01-DEC-05. |
| Cryan J.F.; (2004) From Academia to Industry: A Personal Perspective. [Invited Lectures (Conference)], From Academia to Industry: A Personal Perspective, . |
| Cryan, J. F.; (2003) In search of a depressed mouse: models for studying depression-related behaviour in genetically modified mice. [Oral Presentation], Unknown, ETH Zurich , 01-OCT-03 - 01-OCT-03. |
| Cryan J.F.; (2003) Utility of models for studying depression and anxiety-related behavior in genetically modified mice. [Invited Lectures (Conference)], Utility of models for studying depression and anxiety-related behavior in genetically modified mice, . |
| Cryan J.F.; (2003) In search of a depressed mouse: models for studying depression-related behaviour in genetically modified mice. [Invited Lectures (Conference)], In search of a depressed mouse: models for studying depression-related behaviour in genetically modified mice, . |
Committees |
|
| Committee : External Examiner: University Birmingham, BMed Sci Degree From:01-JAN-08 To: |
| Committee : External Examiner: Galway-Mayo Institute of Technology, Bachelor of Science (Honours) in Applied Biology and Biopharmaceutical
Science From:01-JAN-08 To: 01-JAN-08 |
| Committee : PhD Examiner Mr. Lucas Lecourtier, University of Bordeaux From: To: |
| Committee : PhD Examiner Mr Danny Allen, Genetics Dept., Trinity College Dublin From: To: |
| Committee : PhD Examiner Mr. Lawrence Tam, Genetics Dept., Trinity College Dublin From: To: |
| Committee : Quality Review: NUI Galway, BSc Biotechnology Programme From: To: |
Employment |
|
| Employer: School of Pharmacy, University College Cork Position: Senior Lecturer/Principal Investigator From:01-JUL-06 To: |
| Employer: University College Cork Position: Lecturer From:01-JAN-05 To: 31-DEC-06 |
| Employer: Novartis Institutes for BioMedical Research Position: LabHead Behavioural Pharmacology From:01-JAN-02 To: 31-DEC-05 |
| Employer: The Scripps Research Institute Position: Senior Postdoctoral Fellow From:01-JAN-01 To: 31-DEC-01 |
Education |
|
| Year 1995 Institution: NUI Galway Qualification: BSc Hons, (NUI,Galway) Subject: Biochemistry |
| Year 1998 Institution: NUI Galway Qualification: PHD Subject: Pharmacology |
Consultancy |
|
| Client: : National Institutes for Drug Abuse (NIDA): Review and Evaluation of NIDA Targets for Potential NIH Roadmap Library Screening |
Reviews |
|
| Proceedings Of The National Academy Of Science Usa: Referee. |
| Science: Referee. |
| Frontiers In Pharmacology: Editor. |
| Science : Referee. |
| Plos Biology: Referee. |
| Neuropharmacology: Editor. |
| Psychopharmacology: Editor. |
| Brain Research: Member of Editorial Board . |
| Behavioural Pharmacology: Member of Editorial Board . |
| Neuroscience And Biobehavioral Reviews: Member of Editorial Board . |
| Behavioural Brain Research: Referee. |
| Behavior Genetics: Referee. |
| Behavioural Pharmacology: Referee. |
| Brain Research: Referee. |
| British Journal Of Pharmacology: Editor. |
| European Journal Of Pharmacology: Referee. |
| Experimental Brain Research: Referee. |
| Genome Research: Referee. |
| Human Psychopharmacology : Referee. |
| Human Molecular Genetics : Referee. |
| Neuropsychopharmacology : Referee. |
| Journal Of Neural Transmission : Referee. |
| Journal Of Neurochemistry : Referee. |
| Journal Of Neuroscience : Referee. |
| Journal Of Pharmacology And Experimental Therapeutics: Referee. |
| Journal Of Psychopharmacology: Referee. |
| Neuropharmacology: Referee. |
| Neuropsychopharmacology : Referee. |
| Neuroscience: Referee. |
| Neuroscience And Biobehavioral Reviews: Referee. |
| Pharmacogenomics: Referee. |
| Pharmacology Biochemistry And Behavior : Referee. |
| Proceedings Of The National Academy Of Sciences Of The United States Of America: Referee. |
| Psychiatry Research: Referee. |
| Psychopharmacology: Referee. |
| Psychoneuroendocrinology : Referee. |
| Stress And Health : Referee. |
| Synapse (New York, N.Y.): Referee. |
| Trends In Pharmacological Sciences : Referee. |
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