Hyland NP and Cryan JF (2010) 'A Gut Feeling about GABA: Focus on GABA(B) Receptors'. Frontiers In Pharmacology, .  [DOI] [Details]
|
| McKernan, DP,Dennison, U,Gaszner, G,Cryan, JF,Dinan, TG (2011) 'Enhanced peripheral toll-like receptor responses in psychosis:
further evidence of a pro-inflammatory phenotype'. Translational Psychiatry, 1 . [DOI] [Details]
|
| O'Sullivan, E,Barrett, E,Grenham, S,Fitzgerald, P,Stanton, C,Ross, RP,Quigley, EMM,Cryan, JF,Dinan, TG (2011) 'BDNF expression
in the hippocampus of maternally separated rats: does Bifidobacterium breve 6330 alter BDNF levels?'. Beneficial microbes, 2 :199-207. [DOI] [Details]
|
| O'Mahony, AM,Ogier, J,Desgranges, S,Cryan, JF,Darcy, R,O'Driscoll, CM (2012) 'A click chemistry route to 2-functionalised
PEGylated and cationic beta-cyclodextrins: co-formulation opportunities for siRNA delivery'. Organic & Biomolecular Chemistry, 10 :4954-4960. [DOI] [Full Text] [Details]
|
| O'Brien, FE,Clarke, G,Fitzgerald, P,Dinan, TG,Griffin, BT,Cryan, JF (2012) 'Inhibition of P-glycoprotein enhances transport
of imipramine across the blood-brain barrier: microdialysis studies in conscious freely moving rats'. British Journal of Pharmacology, 166 :1333-1343. [DOI] [Details]
|
| Slattery, DA,Cryan, JF (2012) 'Using the rat forced swim test to assess antidepressant-like activity in rodents'. Nature Protocols, 7 :1009-1014. [DOI] [Details]
|
| O'Mahony SM, Tramullas M, Fitzgerald P, Cryan JF (2012) 'Rodent models of colorectal distension'. Current protocols in neuroscience / editorial board, Jacqueline N. Crawley ... [et al.], Chapter 9 . [DOI] [Details]
|
| Schellekens, H,Clarke, G,Jeffery, IB,Dinan, TG,Cryan, JF (2012) 'Dynamic 5-HT2C Receptor Editing in a Mouse Model of Obesity'.
Plos One, 7 . [DOI] [Details]
|
| Finger, BC,Dinan, TG,Cryan, JF (2012) 'The temporal impact of chronic intermittent psychosocial stress on high-fat diet-induced
alterations in body weight'. Psychoneuroendocrinology, 37 :729-741. [DOI] [Details]
|
| Julio-Pieper, M,O'Mahony, CM,Clarke, G,Bravo, JA,Dinan, TG,Cryan, JF (2012) 'Chronic stress-induced alterations in mouse colonic
5-HT and defecation responses are strain dependent'. Stress (Amsterdam, Netherlands), 15 :218-226. [DOI] [Details]
|
| O'Leary, OF,O'Connor, RM,Cryan, JF (2012) 'Lithium-induced effects on adult hippocampal neurogenesis are topographically segregated
along the dorso-ventral axis of stressed mice'. Neuropharmacology, 62 :247-255. [DOI] [Details]
|
| Finger, BC,Dinan, TG,Cryan, JF (2012) 'Diet-induced obesity blunts the behavioural effects of ghrelin: studies in a mouse-progressive
ratio task'. Psychopharmacology, 220 :173-181. [DOI] [Details]
|
| Felice D, O'Leary OF, Pizzo RC, Cryan JF. (2012) 'Blockade of the GABA(B) receptor increases neurogenesis in the ventral but
not dorsal adult hippocampus: Relevance to antidepressant action'. Neuropharmacology, 63 (8):1380-1388. [DOI] [Details]
|
| O'Connor RM, Pusceddu M, O'Leary OF, Savignac HM, Bravo JF, El Yacoubi M, Vaugeois JM, Dinan TG, Cryan JF. (2013) 'Hippocampal
group III mGlu receptor mRNA levels are not altered in specific mouse models of stress, depression and antidepressant action'.
Pharmacology Biochemistry and Behavior, 103 (3):561-567. [DOI] [Details]
|
| o'Leary OF, Zandy S, Dinan TG, Cryan JF (2013) 'Lithium Augmentation of the effects of Desipramine in a Mouse Model of Treatment-Resistant
Depression: A Role for Hippocampal Cell Proliferation'. Neuroscience, 228 :36-46. [DOI] [Details]
|
| Browne, CA,Clarke, G,Hanke, J,Dinan, TG,Schwegler, H,Yilmazer-Hanke, DM,Cryan, JF (2013) 'Alterations in prefrontal cortical
serotonin and antidepressant-like behavior in a novel C3H/HeJxDBA/2J recombinant inbred mouse strain'. Behavioural Brain Research, 236 :283-288. [DOI] [Details]
|
| Cryan JF, O'Leary OF, Jin SH, Friedland JC, Ouyang M, Hirsch BR, Page ME, Dalvi A, Thomas SA, Lucki I; (2004) 'Norepinephrine-deficient
mice lack responses to antidepressant drugs, including selective serotonin reuptake inhibitors'. Proceedings of The National Academy of Sciences of The United States of America, 101 (21):8186-8191. [DOI] [Details]
|
| Hyland NP, Cryan JF (2010) 'A Gut Feeling about GABA: Focus on GABA(B) Receptors'. Frontiers In Pharmacology, 1 . [DOI] [Details]
|
| O'Malley, D,Dinan, TG,Cryan, JF; (2011) 'Altered expression and secretion of colonic Interleukin-6 in a stress-sensitive animal
model of brain-gut axis dysfunction'. The Journal of Immunology, 235 :48-55. [DOI] [Details]
|
| O'Leary OF, O'Connor RM, Cryan JF; (2012) 'Lithium-induced effects on adult hippocampal neurogenesis are topographically segregated
along the dorso-ventral axis of stressed mice'. Neuropharmacology, 62 (1):247-255. [DOI] [Details]
|
| O'Tuathaigh CM, Clarke G, Walsh J, Desbonnet L, Petit E, O'Leary C, Tighe O, Clarke N, Karayiorgou M, Gogos JA, Dinan TG,
Cryan JF, Waddington JL (2011) 'Genetic vs. pharmacological inactivation of COMT influences cannabinoid-induced expression
of schizophrenia-related phenotypes'. International Journal of Neuropsychopharmacology, :1-12. [DOI] [Details]
|
| O'Sullivan E, Barrett E, Grenham S, Fitzgerald P, Stanton C, Ross RP, Quigley EM, Cryan JF, Dinan TG (2011) 'BDNF expression
in the hippocampus of maternally separated rats: does Bifidobacterium breve 6330 alter BDNF levels?'. Beneficial microbes, 2 (3):199-207. [DOI] [Details]
|
| O'Malley D, Quigley EM, Dinan TG, Cryan JF (2011) 'Do interactions between stress and immune responses lead to symptom exacerbations
in irritable bowel syndrome?'. Brain : a journal of neurology, 25 (7):1333-1341. [DOI] [Details]
|
| Finger, BC,Dinan, TG,Cryan, JF; (2011) 'Behavioral satiety sequence in a genetic mouse model of obesity: effects of ghrelin
receptor ligands'. Behavioural Pharmacology, 22 :624-632. [DOI] [Details]
|
| Bravo, JA,Forsythe, P,Chew, MV,Escaravage, E,Savignac, HM,Dinan, TG,Bienenstock, J,Cryan, JF; (2011) 'Ingestion of Lactobacillus
strain regulates emotional behavior and central GABA receptor expression in a mouse via the vagus nerve'. Proceedings of The National Academy of Science Usa, 108 :16050-16055. [DOI] [Details]
|
| O'Mahony, SM,Coelho, AM,Fitzgerald, P,Lee, K,Winchester, W,Dinan, TG,Cryan, JF; (2011) 'The effects of gabapentin in two animal
models of co-morbid anxiety and visceral hypersensitivity'. European Journal of Pharmacology, 667 :169-174. [DOI] [Details]
|
| Finger, BC,Dinan, TG,Cryan, JF (2011) 'HIGH-FAT DIET SELECTIVELY PROTECTS AGAINST THE EFFECTS OF CHRONIC SOCIAL STRESS IN
THE MOUSE'. Neuroscience, 192 :351-360. [DOI] [Details]
|
| Grenham S, Clarke G, Cryan JF, Dinan TG (2011) 'Brain-gut-microbe communication in health and disease'. Frontiers in Physiology, 2 . [DOI] [Details]
|
| Bravo JA, Forsythe P, Chew MV, Escaravage E, Savignac HM, Dinan TG, Bienenstock J, Cryan JF (2011) 'Ingestion of Lactobacillus
strain regulates emotional behavior and central GABA receptor expression in a mouse via the vagus nerve'. Proceedings of The National Academy of Sciences of The United States of America, 108 (38):16050-16055. [DOI] [Details]
|
| Finger BC, Dinan TG, Cryan JF (2011) 'High-fat diet selectively protects against the effects of chronic social stress in the
mouse'. Science (New York, N.Y.), 192 :351-360. [DOI] [Details]
|
| O' Mahony SM, Coelho AM, Fitzgerald P, Lee K, Winchester W, Dinan TG, Cryan JF (2011) 'The effects of gabapentin in two animal
models of co-morbid anxiety and visceral hypersensitivity'. European Journal of Pharmacology, 667 (1-3):169-174. [DOI] [Details]
|
| Cryan JF, Sweeney FF (2011) 'The age of anxiety: role of animal models of anxiolytic action in drug discovery'. British Journal of Pharmacology, 164 (4):1129-1161. [DOI] [Details]
|
| Savignac HM, Dinan TG, Cryan JF (2011) 'Resistance to early-life stress in mice: effects of genetic background and stress
duration'. Behavioral Neuroscience, 5 . [DOI] [Details]
|
| McKernan DP, Gaszner G, Quigley EM, Cryan JF, Dinan TG (2011) 'Altered peripheral toll-like receptor responses in the irritable
bowel syndrome'. Pharmacology & Therapeutics, 33 (9):1045-1052. [DOI] [Details]
|
| Kennedy, P.J., G. Clarke, G., Quigley, E.M.M., Groeger., J.A., Dinan., T.G., Cryan. J.F. ; (2011) 'Gut Memories: Towards a
Cognitive Neurobiology of Irritable Bowel Syndrome'. Neuroscience and Biobehavioral Reviews, . [Details]
|
| O'Malley D, Dinan TG, Cryan JF (2011) 'Altered expression and secretion of colonic interleukin-6 in a stress-sensitive animal
model of brain-gut axis dysfunction'. Journal of Neuroimmunology, 235 (1-2):48-55. [DOI] [Details]
|
| Tramullas M, Dinan TG, Cryan JF (2011) 'Chronic psychosocial stress induces visceral hyperalgesia in mice'. Stress (Amsterdam, Netherlands), . [DOI] [Details]
|
| Savignac HM, Finger BC, Pizzo RC, O'Leary OF, Dinan TG, Cryan JF; (2011) 'Increased sensitivity to the effects of chronic
social defeat stress in an innately anxious mouse strain'. Neuroscience, 192 :524-536. [DOI] [Details]
|
| Julio-Pieper M, O'Mahony CM, Clarke G, Bravo JA, Dinan TG, Cryan JF (2012) 'Chronic stress-induced alterations in mouse colonic
5-HT and defecation responses are strain dependent'. Stress (Amsterdam, Netherlands), . [DOI] [Details]
|
| Kennedy PJ, Clarke G, Quigley EM, Groeger JA, Dinan TG, Cryan JF (2012) 'Gut memories: towards a cognitive neurobiology of
irritable bowel syndrome'. Neuroscience and Biobehavioral Reviews, 36 (1):310-340. [DOI] [Details]
|
| Schellekens H, Clarke G, Jeffery IB, Dinan TG, Cryan JF (2012) 'Dynamic 5-HT(2C) Receptor Editing in a Mouse Model of Obesity'.
Plos One, 7 (3). [DOI] [Full Text] [Details]
|
| Desbonnet L, O'Tuathaigh C, Clarke G, O'Leary C, Petit E, Clarke N, Tighe O, Lai D, Harvey R, Cryan JF, Dinan TG, Waddington
JL (2012) 'Phenotypic effects of repeated psychosocial stress during adolescence in mice mutant for the schizophrenia risk
gene neuregulin-1: A putative model of gene×environment interaction'. Brain Behav Immun, . [Details]
|
| Dennison U, McKernan D, Cryan J, Dinan T (2012) 'Schizophrenia patients with a history of childhood trauma have a pro-inflammatory
phenotype'. Psychological medicine, :1-7. [DOI] [Details]
|
| Davey KJ, O'Mahony SM, Schellekens H, O'Sullivan O, Bienenstock J, Cotter PD, Dinan TG, Cryan JF (2012) 'Gender-dependent
consequences of chronic olanzapine in the rat: effects on body weight, inflammatory, metabolic and microbiota parameters'.
Pharmacology, 221 (1):155-169. [DOI] [Details]
|
| Finger BC, Dinan TG, Cryan JF (2012) 'Diet-induced obesity blunts the behavioural effects of ghrelin: studies in a mouse-progressive
ratio task'. Pharmacology, 220 (1):173-181. [DOI] [Details]
|
| Clarke, G; McKernan, D; Gaszner, G; Quigley, E; Cryan, J; Dinan, T (2012) 'A Distinct Profile of Tryptophan Metabolism along
the Kynurenine Pathway Downstream of Toll-Like Receptor Activation in Irritable Bowel Syndrome'. Frontiers In Pharmacology, 3:90 . [DOI] [Details]
|
| Clarke, G; Grenham, S; Scully, P; Fitzgerald, P; Moloney, R; Shanahan, F; Dinan, T; Cryan, J (2012) 'The Microbiome-Gut-Brain
Axis During Early-Life Regulates the Hippocampal Serotonergic System in a Sex-Dependent Manner'. Molecular Psychiatry, . [Details]
|
| Desbonnet, L,O'Tuathaigh, C,Clarke, G,O'Leary, C,Petit, E,Clarke, N,Tighe, O,Lai, D,Harvey, R,Cryan, JF,Dinan, TG,Waddington,
JL (2012) 'Phenotypic effects of repeated psychosocial stress during adolescence in mice mutant for the schizophrenia risk
gene neuregulin-1: A putative model of gene x environment interaction'. Brain Behav Immun, 26 :660-671. [DOI] [Details]
|
| Davey, KJ,O'Mahony, SM,Schellekens, H,O'Sullivan, O,Bienenstock, J,Cotter, PD,Dinan, TG,Cryan, JF (2012) 'Gender-dependent
consequences of chronic olanzapine in the rat: effects on body weight, inflammatory, metabolic and microbiota parameters'.
Psychopharmacology, 221 :155-169. [DOI] [Details]
|
| Camp, MC,MacPherson, KP,Lederle, L,Graybeal, C,Gaburro, S,DeBrouse, LM,Ihne, JL,Bravo, JA,O'Connor, RM,Ciocchi, S,Wellman,
CL,Luthi, A,Cryan, JF,Singewald, N,Holmes, A (2012) 'Genetic Strain Differences in Learned Fear Inhibition Associated with
Variation in Neuroendocrine, Autonomic, and Amygdala Dendritic Phenotypes'. Neuropsychopharmacology, 37 :1534-1547. [DOI] [Details]
|
| Tramullas, M,Dinan, TG,Cryan, JF (2012) 'Chronic psychosocial stress induces visceral hyperalgesia in mice'. Stress (Amsterdam, Netherlands), 15 :281-292. [DOI] [Details]
|
| Moloney, RD,O'Leary, OF,Felice, D,Bettler, B,Dinan, TG,Cryan, JF (2012) 'Early-life stress induces visceral hypersensitivity
in mice'. Neuroscience Letters, 512 :99-102. [DOI] [Details]
|
| Browne, CA,Clarke, G,Dinan, TG,Cryan, JF (2012) 'An effective dietary method for chronic tryptophan depletion in two mouse
strains illuminates a role for 5-HT in nesting behaviour'. Neuropharmacology, 62 :1903-1915. [DOI] [Details]
|
| Dennison, U,McKernan, DP,Scully, P,Clarke, G,Cryan, J,Dinan, T (2012) 'Menstrual Cycle Influences Toll-Like Receptor Responses'.
Neuroimmunomodulation, 19 :171-179. [DOI] [Details]
|
| Finger BC, Dinan TG, Cryan JF (2012) 'The temporal impact of chronic intermittent psychosocial stress on high-fat diet-induced
alterations in body weight'. Psychoneuroendocrinology, 37 (6):729-741. [DOI] [Details]
|
| O'Connor RM, Dinan TG, Cryan JF (2012) 'Little things on which happiness depends: microRNAs as novel therapeutic targets for
the treatment of anxiety and depression'. Molecular Psychiatry, 17 (4):359-376. [DOI] [Details]
|
| Moloney RD, O'Leary OF, Felice D, Bettler B, Dinan TG, Cryan JF (2012) 'Early-life stress induces visceral hypersensitivity
in mice'. Neuroscience Letters, 512 (2):99-102. [DOI] [Details]
|
| Dinan TG, Cryan JF (2012) 'Regulation of the stress response by the gut microbiota: Implications for psychoneuroendocrinology'.
Psychoneuroendocrinology, . [DOI] [Details]
|
| Moloney RD, O'Leary OF, Felice D, Bettler B, Dinan TG, Cryan JF. (2012) 'Early-life stress induces visceral hypersensitivity
in mice'. Neuroscience Letters, 512 (2):99-102. [Details]
|
| Browne CA, Clarke G, Dinan TG, Cryan JF (2012) 'An effective dietary method for chronic tryptophan depletion in two mouse
strains illuminates a role for 5-HT in nesting behaviour'. Neuropharmacology, . [DOI] [Details]
|
| Clarke G, Cryan JF, Dinan TG, Quigley EM (2012) 'Review article: probiotics for the treatment of irritable bowel syndrome
- focus on lactic acid bacteria'. Alimentary Pharmacology And Therapeutics, 35 (4):403-413. [DOI] [Details]
|
| O'Brien FE, Clarke G, Fitzgerald P, Dinan TG, Griffin BT, Cryan JF (2012) 'Inhibition of P-glycoprotein Enhances Transport
of the Antidepressant Imipramine across the Blood-Brain Barrier: Microdialysis Studies in the Conscious Freely Moving Rat'.
British Journal of Pharmacology, . [DOI] [Details]
|
| Dennison U, McKernan DP, Scully P, Clarke G, Cryan J, Dinan T (2012) 'Menstrual Cycle Influences Toll-Like Receptor Responses'.
Neuroimmunomodulation, 19 (3):171-179. [DOI] [Details]
|
| O'Brien FE, Dinan TG, Griffin BT, Cryan JF; (2011) 'Interactions between antidepressants and P-glycoprotein at the blood-brain
barrier: Clinical significance of in vitro and in vivo findings'. British Journal of Pharmacology, . [DOI] [Details]
|
| Julio-Pieper M, Flor PJ, Dinan TG, Cryan JF; (2011) 'Exciting Times beyond the Brain: Metabotropic Glutamate Receptors in
Peripheral and Non-Neural Tissues'. Pharmacological reviews, . [DOI] [Details]
|
| Cryan JF, O'Mahony SM; (2011) 'The microbiome-gut-brain axis: from bowel to behavior'. Neurogastroenterology and Motility, 23 (3):187-192. [DOI] [Details]
|
| Browne CA, Clarke G, Dinan TG, Cryan JF; (2011) 'Differential stress-induced alterations in tryptophan hydroxylase activity
and serotonin turnover in two inbred mouse strains'. Neuropharmacology, 60 (4):683-691. [DOI] [Details]
|
| McKernan, DP,Gaszner, G,Quigley, EM,Cryan, JF,Dinan, TG; (2011) 'Altered peripheral toll-like receptor responses in the irritable
bowel syndrome'. Alimentary Pharmacology & Therapeutics, 33 :1045-1052. [DOI] [Details]
|
| Bravo, JA,Dinan, TG,Cryan, JF; (2011) 'Alterations in the central CRF system of two different rat models of comorbid depression
and functional gastrointestinal disorders'. International Journal of Neuropsychopharmacology, 14 :666-683. [DOI] [Details]
|
| Finger BC, Schellekens H, Dinan TG, Cryan JF; (2011) 'Is there altered sensitivity to ghrelin-receptor ligands in leptin-deficient
mice?: importance of satiety state and time of day'. Psychopharmacology, . [DOI] [Details]
|
| Gosselin, RD; O'Connor, RM; Tramullas, M; Julio-Pieper, M; Dinan, TG; Cryan, JF; (2010) 'Riluzole Normalizes Early-Life Stress-induced
Visceral Hypersensitivity in Rats: Role of Spinal Glutamate Reuptake Mechanisms'. Gastroenterology, . [DOI] [Details]
|
| Schellekens, H; Dinan, TG; Cryan, JF; (2010) 'Lean mean fat reducing ghrelin machine: hypothalamic ghrelin and ghrelin receptors
as therapeutic targets in obesity'. Neuropharmacology, 58 (1):2-16. [DOI] [Details]
|
| Gibney, SM; Gosselin, RD; Dinan, TG; Cryan, JF; (2010) 'Colorectal distension-induced prefrontal cortex activation in the
Wistar-Kyoto rat: implications for irritable bowel syndrome'. Neuroscience, 165 (3):675-683. [DOI] [Details]
|
| O'Connor, RM; Finger, BC; Flor, PJ; Cryan, JF; (2010) 'Metabotropic glutamate receptor 7: At the interface of cognition and
emotion'. European Journal of Pharmacology, . [DOI] [Details]
|
| Slattery, DA; Neumann, I; Cryan, JF; (2010) 'Transient inactivation of the infralimbic cortex induces antidepressant-like
effects in the rat'. Journal of Psychopharmacology, . [DOI] [Details]
|
| O'Malley, D; Dinan, TG; Cryan, JF; (2010) 'Neonatal maternal separation in the rat impacts on the stress responsivity of central
corticotropin-releasing factor receptors in adulthood'. Psychopharmacology, . [DOI] [Details]
|
| O'Mahony, CM; Sweeney, FF; Daly, E; Dinan, TG; Cryan, JF; (2010) 'Restraint stress-induced brain activation patterns in two
strains of mice differing in their anxiety behaviour'. Behavioural Brain Research, 213 :148-154. [DOI] [Details]
|
| O'Mahony, SM; Bulmer, DC; Coelho, AM; Fitzgerald, P; Bongiovanni, C; Lee, K; Winchester, W; Dinan, TG; Cryan, JF; (2010) '5-HT2B
receptors modulate visceral hypersensitivity in a stress-sensitive animal model of brain-gut axis dysfunction'. Neurogastroenterology and Motility, 22 . [DOI] [Details]
|
| Levav-Rabkin, T; Melamed, O; Clarke, G; Farber, M; Cryan, JF; Dinan, TG; Grossman, Y; Golan, HM; (2010) 'A Sensitive Period
of Mice Inhibitory System to Neonatal GABA Enhancement by Vigabatrin is Brain Region Dependent'. Neuropsychopharmacology, 35 :1138-1154. [DOI] [Details]
|
| Cryan JF, Slattery DA; (2010) 'GABAB receptors and depression. Current status'. Advances In Pharmacology, 58 :427-451. [DOI] [Details]
|
| Dinan, Timothy G; Cryan, John; Shanahan, Fergus; Keeling, PW Napoleon; Quigley, Eamonn MM; (2010) 'IBs: an epigenetic perspective'.
Nature Reviews Gastroenterology & Hepatology, 7 (8):465-471. [DOI] [Details]
|
| O'Mahony CM, Clarke G, Gibney S, Dinan TG, Cryan JF; (2010) 'Strain differences in the neurochemical response to chronic restraint
stress in the rat: Relevance to depression'. Pharmacology, Biochemistry, and Behavior, . [DOI] [Details]
|
| Hyland, NP; Cryan, JF; (2010) 'A Gut Feeling about GABA: Focus on GABAB receptors'. Frontiers in Pharmacology, . [DOI] [Details]
|
| O'Mahony, SM; Hyland, NP; Dinan, TG; Cryan, JF; (2010) 'Maternal separation as a model of brain-gut axis dysfunction'. Psychopharmacology, . [DOI] [Details]
|
| O'Malley D, Liston M, Hyland NP, Dinan TG, Cryan JF; (2010) 'Colonic Soluble Mediators from the Maternal Separation Model
of Irritable Bowel Syndrome Activate Submucosal Neurons via an Interleukin-6-dependent Mechanism'. American Journal of Physiology - Gastrointestinal and Liver Physiology, . [DOI] [Details]
|
| Clarke, G; Fitzgerald, P; Hennessy, AA; Cassidy, EM; Quigley, EMM; Ross, P; Stanton, C; Cryan, JF; Dinan, TG; (2010) 'Marked
elevations in pro-inflammatory polyunsaturated fatty acid metabolites in females with irritable bowel syndrome'. Journal of Lipid Research, 51 :1186-1192. [DOI] [Details]
|
| O'Malley, D; Julio-Pieper, M; Gibney, SM; Dinan, TG; Cryan, JF; (2010) 'Distinct alterations in colonic morphology and physiology
in two rat models of enhanced stress-induced anxiety and depression-like behaviour'. Stress (Amsterdam, Netherlands), 13 :114-122. [DOI] [Details]
|
| O'Malley, D; Julio-Pieper, M; Gibney, SM; Gosselin, RD; Dinan, TG; Cryan, JF; (2010) 'Differential stress-induced alterations
of colonic corticotropin-releasing factor receptors in the Wistar Kyoto rat'. Neurogastroenterology and Motility, 22 :301-311. [DOI] [Details]
|
| Cryan JF, O'Leary OF; (2010) 'Neuroscience. A glutamate pathway to faster-acting antidepressants?'. Science, 329 (5994):913-914. [DOI] [Details]
|
| Finger BC, Dinan TG, Cryan JF; (2010) 'Progressive ratio responding in an obese mouse model: Effects of fenfluramine'. Neuropharmacology, 59 (7-8):619-626. [DOI] [Details]
|
| Pieper-Julio, M; Hyland, NP; Bravo, JA; Dinan, TG; Cryan, JF; (2010) 'A novel role for the metabotropic glutamate receptor-7:
modulation of faecal water content and colonic electrolyte transport in the mouse'. British Journal of Pharmacology, 160 :367-375. [DOI] [Details]
|
| O'Malley, D; Dinan, TG; Cryan, JF; (2010) 'Alterations in colonic corticotropin-releasing factor receptors in the maternally
separated rat model of irritable bowel syndrome: Differential effects of acute psychological and physical stressors'. Peptides, 31 :662-670. [DOI] [Details]
|
| Savignac, HM; Hyland, NP; Dinan, TG; Cryan, JF; (2010) 'The effects of repeated social interaction stress on behavioural and
physiological parameters in a stress-sensitive mouse strain'. Behavioural Brain Research, . [DOI] [Details]
|
| McKernan, DP; Fitzgerald, P; Dinan, TG; Cryan, JF; (2010) 'The probiotic Bifidobacterium infantis 35624 displays visceral
antinociceptive effects in the rat'. Neurogastroenterology and Motility, . [DOI] [Details]
|
| O'Mahony, CM; Bravo, J; Dinan, TG; Cryan, JF; (2010) 'Comparison of Hippocampal Metabotropic Glutamate Receptor 7 (mGlu(7))
mRNA Levels in Two Animal Models of Depression'. Neuroscience Letters, . [DOI] [Details]
|
| Guo, J; Fisher, KA; Darcy, R; Cryan, JF; O'Driscoll, C; (2010) 'Therapeutic targeting in the silent era: advances in non-viral
siRNA delivery'. Molecular Biosystems, 6 (7):1143-1161. [DOI] [Full Text] [Details]
|
| Finger, BC; Dinan, TG; Cryan JF; (2010) 'Leptin-deficient mice retain normal appetitive spatial learning yet exhibit marked
increases in anxiety-related behaviours'. Psychopharmacology, . [DOI] [Details]
|
| Gosselin RD, Gibney S, O'Malley D, Dinan TG, Cryan JF; (2009) 'Region specific decrease in glial fibrillary acidic protein
immunoreactivity in the brain of a rat model of depression'. Neuroscience, 159 (2):915-925. [DOI] [Details]
|
| McKernan, DP,Nolan, A,Brint, EK,O'Mahony, SM,Hyland, NP,Cryan, JF,Dinan, TG; (2009) 'Toll-Like Receptor mRNA Expression Is
Selectively Increased in the Colonic Mucosa of Two Animal Models Relevant to Irritable Bowel Syndrome'. Plos One, 4 . [DOI] [Details]
|
| Clarke, G,O'Mahony, SM,Hennessy, AA,Ross, P,Stanton, C,Cryan, JF,Dinan, TG; (2009) 'Chain reactions: Early-life stress alters
the metabolic profile of plasma polyunsaturated fatty acids in adulthood'. Behavioural Brain Research, 205 :319-321. [DOI] [Details]
|
| Gosselin, RD,Gibney, S,O'Malley, D,Dinan, TG,Cryan, JF; (2009) 'REGION SPECIFIC DECREASE IN GLIAL FIBRILLARY ACIDIC PROTEIN
IMMUNOREACTIVITY IN THE BRAIN OF A RAT MODEL OF DEPRESSION'. Neuroscience, 159 :915-925. [DOI] [Details]
|
| Clarke, G.,Fitzgerald, P.,Cryan, J. F.,Cassidy, E. M.,Quigley, E. M.,Dinan, T. G.; (2009) 'Tryptophan degradation in irritable
bowel syndrome: evidence of indoleamine 2,3-dioxygenase activation in a male cohort. BMC Gastroenterol'. BMC Gastroenterol, 9 . [Details]
|
| Casanova E, Guetg N, Vigot R, Seddik R, Julio-Pieper M, Hyland NP, Cryan JF, Gassmann M, Bettler B; (2009) 'A mouse model
for visualization of GABA(B) receptors'. Genesis, 47 (9):595-602. [DOI] [Details]
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| McKernan DP, Dinan TG, Cryan JF; (2009) 'Killing the Blues: a role for cellular suicide (apoptosis) in depression and the
antidepressant response?'. Progress In Neurobiology, 88 (4):246-263. [DOI] [Details]
|
| Glynn DA, Cryan JF, Kent P, Flynn RA, Kennedy MP; (2009) 'Update on smoking cessation therapies'. Advances In Therapy, 26 (4):369-382. [DOI] [Details]
|
| Clarke G, O'Mahony SM, Cryan JF, Dinan TG; (2009) 'Verapamil in treatment resistant depression: a role for the P-glycoprotein
transporter?'. Human Psychopharmacology, 24 (3):217-223. [DOI] [Details]
|
| Clarke, G; Quigley, EM; Cryan, JF; Dinan, TG; (2009) 'Irritable bowel syndrome: towards biomarker identification'. Trends In Molecular Medicine, 15 (10):478-489. [DOI] [Details]
|
| Hyland, NP, Julio-Pieper, M, O'Mahony, SM, Bulmer, DC, Lee, K, Quigley, EM, Dinan, TG, Cryan, JF; (2009) 'A Distinct Subset
of Submucosal Mast Cells Undergoes Hyperplasia Following Neonatal Maternal Separation: A Role In Visceral Hypersensitivity?'.
Gut, (7):1029-1030. [DOI] [Details]
|
| Bissiere, S, Plachta, N, Hoyer, D, McAllister, KH, Olpe, HR, Grace, AA, Cryan, JF; (2008) 'The Rostral Anterior Cingulate
Cortex Modulates The Efficiency of Amygdala-Dependent Fear Learning'. Biological Psychiatry, 63 (9):821-831. [DOI] [Details]
|
| Dinan TG, Clarke G, Quigley EM, Scott LV, Shanahan F, Cryan J, Cooney J, Keeling PW; (2008) 'Enhanced cholinergic-mediated
increase in the pro-inflammatory cytokine IL-6 in irritable bowel syndrome: role of muscarinic receptors'. The American Journal of Gastroenterology, 103 (10):2570-2576. [DOI] [Details]
|
| Fitzgerald, P,Eugene, MC,Clarke, G,Scully, P,Barry, S,Eamonn, MMQ,Shanahan, F,Cryan, J,Timothy, GD; (2008) 'Tryptophan catabolism
in females with irritable bowel syndrome: relationship to interferon-gamma, severity of symptoms and psychiatric co-morbidity'.
Neurogastroenterology and Motility, 20 :1291-1297. [DOI] [Details]
|
| Jacobson, LH,Cryan, JF; (2008) 'Evaluation of the anxiolytic-like profile of the GABA(B) receptor positive modulator CGP7930
in rodents'. Neuropharmacology, 54 :854-862. [DOI] [Details]
|
| Fendt, M,Schmid, S,Thakker, DR,Jacobson, LH,Yamamoto, R,Mitsukawa, K,Maier, R,Natt, F,Husken, D,Kelly, PH,McAllister, KH,Hoyer,
D,van der Putten, H,Cryan, JF,Flor, PJ; (2008) 'mGluR7 facilitates extinction of aversive memories and controls amygdala plasticity'.
Molecular Psychiatry, 13 :970-979. [DOI] [Details]
|
| Jacobson LH, Kelly PH, Bettler B, Kaupmann K and Cryan JF ; (2008) 'Specific roles of GABAB(1) receptor isoforms in cognition'.
Behavioural brain research, (181):158-162. [Details]
|
| Stachowicz K, Brañski P, Kłak K, van der Putten H, Cryan JF, Flor PJ, Andrzej P; (2008) 'Selective activation of metabotropic
G-protein-coupled glutamate 7 receptor elicits anxiolytic-like effects in mice by modulating GABAergic neurotransmission'.
Behavioural Pharmacology, . [Details]
|
| 5. Fendt, M., Schmid, S., Thakker, D.R., Jacobson, L.H., Yamamota, R. Mitsukawa, K. Maier, R, McAllister, K.H., Hoyer, D.
van der Putten, H. Cryan JF and Flor, P.J; (2008) 'Activation of mGluR7 alters amygdala plasticity and facilitates extinction
of fear memories'. Molecular Psychiatry, . [Details]
|
| 2. O' Mahony SM, Marchesi J, Scully P, Codling C, Ceolho A-M, Quigley EMM, Cryan JF, and Dinan TG; (2008) 'Early life stress
alters behaviour, immunity and microbiota: implications for irritable bowel syndrome and psychiatric illnesses'. Biological Psychiatry, . [Details]
|
| Fendt, M, Schmid, S, Thakker, DR, Jacobson, LH, Yamamoto, R, Mitsukawa, K, Maier, R, Natt, F, Husken, D, Kelly, PH, McAllister,
KH, Hoyer, D, van der Putten, H, Cryan, JF, Flor, PJ; (2008) 'Mglur7 Facilitates Extinction of Aversive Memories and Controls
Amygdala Plasticity'. Molecular Psychiatry, 13 (10):970-979. [DOI] [Details]
|
| Senechal, Y, Kelly, PH, Cryan, JF, Natt, F, Dev, KK; (2007) 'Amyloid Precursor Protein Knockdown By Sirna Impairs Spontaneous
Alternation In Adult Mice'. Journal of Neurochemistry, 102 (6):1928-1940. [DOI] [Details]
|
| Slattery, DA, Markou, A, Cryan, JF; (2007) 'Evaluation of Reward Processes In An Animal Model of Depression'. Psychopharmacology, 190 (4):555-568. [DOI] [Details]
|
| Lhuillier L., Mombereau C., *Cryan JF and *Kaupmann, K. ; (2007) 'GABAB Receptor positive modulation decreases selective molecular
and behavioral effects of cocaine'. Neuropsychopharmacology, (32):388-398. [Details]
|
| Cryan, JF,Slattery, DA; (2007) 'Animal models of mood disorders: recent developments'. Current Opinion In Psychiatry, 20 :1-7. [Details]
|
| Mombereau, C,Lhuillier, L,Kaupmann, K,Cryan, JF; (2007) 'GABA(B) receptor-positive modulation-induced blockade of the rewarding
properties of nicotine is associated with a reduction in nucleus accumbens Delta FosB accumulation'. Journal of Pharmacology and Experimental Therapeutics, 321 :172-177. [DOI] [Details]
|
| Jacobson LH and Cryan JF; (2007) 'Feeling strained? Influence of genetic background on depression-related behavior in mice:
A review'. Behavior Genetics, (37):171-213. [Details]
|
| Jacobson LH, Kaupmann, K., Bettler., Cryan JF ; (2007) 'Behavioural evaluation of mice deficient in GABAB(1) receptor isoforms
in tests of unconditioned anxiety'. Psychopharmacology, (190):541-553. [Details]
|
| Rosenzweig-Lipson S, Sabb A, Stack G, Mitchell PJ, Lucki I, Malberg J, Grauer S, Brennan J, Cryan JF, Dunlop J, Barrett J,
Marquis KL; (2007) 'Antidepressant-like effects of the novel, slelective, 5-HT2C receptor agonist WAY-163909 in rodents'.
Psychopharmacology, :159-170. [Details]
|
| Cryan, JF, Driscoll, P, Waddington, JL; (2007) 'Neurogenetics and Behaviour: From Basic Processes to Neuropsychiatric Disorders'.
Neuroscience & Biobehavioral Reviews, (1):1-2. [DOI] [Details]
|
| Sahm L., and Cryan J.F.; (2007) 'Concise Clinical Pharmacology'. Irish Pharmacy Journal, . [Details]
|
| Cryan JF, Thakker DR, Hoyer D; (2007) 'Emerging use of non-viral RNA interference in the brain'. Biochemical Society Transactions, 35 (Pt 2):411-415. [DOI] [Details]
|
| Bissiere, S, McAllister, KH, Olpe, HR, Cryan, JF; (2006) 'The Rostral Anterior Cingulate Cortex Modulates Depression But Not
Anxiety-Related Behaviour In The Rat'. Behavioural Brain Research, 175 (1):195-199. [DOI] [Details]
|
| Jacobson, LH, Bettler, B, Kaupmann, K, Cryan, JF; (2006) 'Gaba(B(1)) Receptor Subunit Isoforms Exert A Differential Influence
On Baseline But Not Gaba(B) Receptor Agonist-Induced Changes In Mice'. Journal of Pharmacology and Experimental Therapeutics, 319 (3):1317-1326. [DOI] [Details]
|
| Slattery DA, Cryan JF; (2006) 'The role of GABAB receptors in depression and the antidepressant response'. Drug Development Research, :477-494. [Details]
|
| Jacobson, LH,Kelly, PH,Bettler, B,Kaupmann, K,Cryan, JF; (2006) 'GABA(B(1)) receptor isoforms differentially mediate the acquisition
and extinction of aversive taste memories'. The Journal of Neuroscience, 26 :8800-8803. [DOI] [Details]
|
| Jacobson, LH,Bettler, B,Kaupmann, K,Cryan, JF; (2006) 'GABA(B(1)) receptor subunit isoforms exert a differential influence
on baseline but not GABA(B) receptor agonist-induced changes in mice'. Journal of Pharmacology and Experimental Therapeutics, 319 :1317-1326. [DOI] [Details]
|
| Vigot R, Barbieri S, Bräuner-Osborne H, Turecek R, Shigemoto R, Zhang YP, Luján R, Jacobson LH, Biermann B, Fritschy JM, Vacher
CM, Müller M, Sansig G, Guetg N, Cryan JF, Kaupmann K, Gassmann M, Oertner TG and Bettler B; (2006) 'Differential compartmentalization
and distinct functions of GABAB receptor variants'. Neuron, (50):589-601. [Details]
|
| Thakker DR, Hoyer D, Cryan JF; (2006) 'Interfering with the brain: The utility of siRNA to unravel the pathophysiology of
psychiatric and neurological disorders'. Pharmacology &Amp; Therapeutics, (109):413-438. [Details]
|
| Hoyer D, Thakker DR, Natt F, Maier R, Huesken D, Müller M, Flor PJ, van der Putten H, Schmutz M, Bilbe, G. and Cryan JF; (2006)
'Global down-regulation of gene expression in the brain using RNA interference, with emphasis on monamine transporters and
GPCRs: implications for target characterization in psychiatric and neurological disorders'. Journal of Receptors and Signal Transduction, (26):527-547. [Details]
|
| Jacobson LH, Kelly PH, Bettler B, Kaupmann K and Cryan JF; (2006) 'GABAB(1) receptor isoforms differentially mediate the acquisition
and the extinction of aversive taste learning'. Journal of Neuroscience, (26):8800-8803. [Details]
|
| Mitsukawa K, Mombereau C, Loetscher E, Uzunov D, van der Putten H, Flor PJ, Cryan JF; (2006) 'Metabotropic glutamate receptor
subtype 7 ablation causes dysregulation of the HPA axis and increases hippocampal BDNF protein levels; implications for stress-related
psychiatric disorders'. Neuropsychopharmacology, :1112-1122. [Details]
|
| Callaerts-Vegh Z, Beckers T, Baeyens F, Callaerts PF, Cryan JF, Molnar E, D'Hooge R; (2006) 'Concomitant deficits in working
memory and fear extinction are functionally dissociated from reduced anxiety in mGluR7-deficient mice'. Journal of Neuroscience, :6573-6582. [Full Text] [Details]
|
| Slattery DA, Markou A. and Cryan JF; (2005) 'The GABAB receptor positive modulator GS39783 and the GABAB receptor agonist
decrease the rewarding effects of cocaine: Intracranial self-stimulation studies in the rat'. Neuropsychopharmacology, 30 (11):2065-2072. [Details]
|
| Thakker DR, Natt F, Husken D, van der Putten H, Maier R, Hoyer D, Cryan JF; (2005) 'siRNA-mediated knockdown of the serotonin
transporter in the adult mouse brain. '. Molecular Psychiatry, 10 (8):782-789. [Details]
|
| Cryan JF, Page M.E. and Lucki I.; (2005) 'Short and long-term administration of reboxetine, fluoxetine and moclobemide differentially
alter behaviour in a modified rat forced swim test'. Psychopharmacology, 6 (*):1-10. [Details]
|
| Cryan JF, Kaupmann K. ; (2005) 'Don't worry 'B' happy!: a role for GABA(B) receptors in anxiety and depression. '. Trends In Pharmacological Sciences, 26 (1):36-43. [Details]
|
| Jacobson LH, Cryan JF; (2005) 'Differential sensitivity to the motor and hypothermic effects of the GABA B receptor agonist
baclofen in various mouse strains. '. Psychopharmacology, 179 (3):688-699. [Details]
|
| Cryan JF, Mombereau C, Vassout A. ; (2005) 'The tail suspension test as a model for assessing antidepressant activity: review
of pharmacological and genetic studies in mice. '. Neuroscience & Biobehavioral Reviews, 29 (4-5):571-625. [Details]
|
| Page, M.E., Szeliga, P.J., Gasparini, F. and Cryan, JF ; (2005) 'Blockade of the Group I metabotropic glutamate receptor mGluR5
decreases basal and stress induced increases in cortical norepinephrine in the rat'. Psychopharmacology, (179):240-246. [Details]
|
| Slattery, D., Desrayaud, S. and Cryan JF ; (2005) 'GABAB receptor-mediated antidepressant-like effects are serotonin dependent'.
Journal of Pharmacology and Experimental Therapeutics, (312):290-296. [Details]
|
| Cryan JF, Valentino RJ, Lucki I; (2005) 'The modified rat forced swim test: Assessing serotonergic influences on depression-related
behavior'. Neuroscience & Biobehavioral Reviews, 29 (4-5):547-569. [Details]
|
| Mombereau C, Kaupmann K, Gassmann M, Bettler B, van der Putten H, Cryan JF. ; (2005) 'Altered anxiety and depression-related
behaviour in mice lacking GABAB(2) receptor subunits. '. Neuroreport, 28 (16):307-310. [Details]
|
| Page ME, Szeliga P, Gasparini F, Cryan JF; (2005) 'Blockade of the mGlu5 receptor decreases basal and stress-induced cortical
norepinephrine in rodents. '. Psychopharmacology, 179 (1):240-246. [Details]
|
| Mitsukawa K, Yamamoto R, Ofner S, Nozulak J, Pescott O, Lukic S, Stoehr N, Mombereau C, Kuhn R, McAllister KH, van der Putten
H, Cryan JF, Flor PJ; (2005) 'The first selective mGluR7 agonist, AMN082 activates receptor signaling via a novel allosteric
site and modulates stress parameters in vivo'. Proceedings of The National Academy of Sciences of The United States of America, :18712-18717. [Details]
|
| Cryan JF, Holmes A; (2005) 'The ascent of mouse: Using mice to model human depression and anxiety'. Nature Reviews Drug Discovery, :775-790. [Details]
|
| Mombereau C., Kaupmann K., Froestl, W. Sansig, G. van der Putten H. and Cryan, JF; (2004) 'Genetic and pharmacological evidence
of a key role for GABAB receptors in the modulation of anxiety and antidepressant-like behaviour'. Neuropsychopharmacology, 29 (6):1050-1062. [Details]
|
| Gassmann M., Shaban H., Vigot R., Sansig G., Haller C., Barbieri S., Humeau Y., Schuler V., Muller M., Kinzel B., Klebs K.,
Schmutz M., Froestl W., Heid J., Kelly P.H., Gentry C., Jaton A.L., Van der Putten H., Mombereau C., Lecourtier L., Mosbacher
J., Cryan JF, Fritschy J.M., Luthi A., Kaupmann K., Bettler B. ; (2004) 'Redistribution of GABAB(1) protein and atypical GABAB
responses in GABAB(2)-deficient mice. '. Journal of Neuroscience, 24 (27):6086-6097. [Details]
|
| Cryan JF, Mombereau C.; (2004) 'In search of a depressed mouse: utility of models for studying depression-related behavior
in genetically modified mice'. Molecular Psychiatry, 9 (4):326-357. [Details]
|
| Cryan, JF, O’Leary O., Hirsch, B.R., Jin S-H, Page M.E., Dalvi A., Thomas S.A. and Lucki I.; (2004) 'Norepinephrine-deficient
mice lack responses to antidepressant drugs, including selective serotonin reuptake inhibitors'. Proceedings of The National Acadamy of Sciences, 101 (*):8186-8191. [Details]
|
| Mombereau C., Kaupmann K., van der Putten H., and Cryan JF; (2004) 'Altered response to benzodiazepine anxiolytics in mice
lacking GABAB(1) receptors'. European Journal of Pharmacology, 497 (1):119-120. [Details]
|
| Cryan JF, Kelly PH, Chaperon F, Gentsch C, Froestl W, Mombereau C, Lingenhoehl K, Bettler B, Kaupmann K, Spooren WPJM; (2004)
'Behavioral characterization of the novel GABAB receptor-positive modulator GS39783 (N,N'-dicyclopentyl-2-methylsulfanyl-5-nitro-pyrimidine-4,6-diamine):
anxiolytic-like activity without side effects associated with baclofen or benzodiazepines'. Journal of Pharmacology and Experimental Therapeutics, :952-963. [Details]
|
| Cryan J.F, Bruijnzeel A.W., Skjei K.S. and Markou A.; (2003) 'The antidepressant bupropion enhances brain reward function
and reverses affective and somatic aspects of nicotine withdrawal'. Psychopharmacology, 168 (*):347-358. [Details]
|
| Cryan J.F., Hoyer D. and Markou A.; (2003) 'Withdrawal from chronic amphetamine induces depression-like behavioural effects
in rodents'. Biological Psychiatry, 54 (*):49-58. [Details]
|
| Cryan J.F., Kelly P.H., Sansig G., Flor P.J. and van Der Putten H.; (2003) 'Antidepressant and anxiolytic-like effects in
mice lacking the group III metabotropic glutamate receptor mGluR7'. European Journal of Neuroscience, 17 (11):2409-2417. [Details]
|
| Cryan J.F., Gasparini F., van Heeke G. and Markou A.; (2003) 'Non-nicotinic neuropharmacological strategies for Smoking Cessation'.
Drug Discovery Today, 8 (22):1025-1034. [Details]
|
| Kaupmann K., Cryan J.F., Wellendorph P., Mombereau C., Sansig G., Klebs K., Schmutz, M., Froestl, W. van der Putten, H., Mosbacher,
J., Bräuner-Osborne, H., Waldmeier, P., and Bettler, B.; (2003) 'Specific ã-Hydroxybutyrate (GHB) binding sites but loss of
pharmacological effects of GHB in GABA-B(1) receptor deficient mice'. European Journal of Neuroscience, 18 (10):2722-2730. [Details]
|
| Page M.E., Cryan J.F., Sulivan A., Dalvi A. and Lucki I.; (2002) 'Neurochemical and behavioral characterization of the novel
5-HT1A receptor partial agonist/serotonin reuptake inhibitor EMD 68843'. The Journal of Pharmacology and Experimental Therapeuti, 302 (3):1220-1227. [Details]
|
| Cryan, J.F. Page M.E., and Lucki. I.; (2002) 'Noradrenergic lesions differentially alter the antidepressant-like effects of
reboxetine'. European Journal of Pharmacology, 436 (3):197-205. [Details]
|
| Conti A.C., Cryan J.F., Dalvi A., Lucki I. and Blendy J.A.; (2002) 'CREB is essential for upregulation of brain derived neurotrophic
factor transcription, but not behavioral or endocrine responses to antidepressant drugs'. Journal of Neuroscience, 15 (22):3262-3268. [Details]
|
| Cryan J.F., Markou A., Lucki I. ; (2002) 'Assessing antidepressant activity in rodents: recent developments and future needs.
'. Trends In Pharmacological Sciences, 23 (5):238-245. [Details]
|
| Cryan J.F., Dalvi A., Hirsch B.R., Jin, S-H, Lucki , I. and Thomas, S.A.; (2001) 'Use of dopamine-beta-hydroxylase-deficient
mice to determine the role of norepinephrine in the mechanism of action of antidepressant drugs. '. The Journal of Pharmacology and Experimental Therapeuti, 298 (2):651-657. [Details]
|
| Cryan J.F. and Lucki I.; (2000) 'Antidepressant-like behavioral effects mediated by 5-Hydroxytryptamine(2C) receptors'. The Journal of Pharmacology and Experimental Therapeuti, 295 (3):1120-1126. [Details]
|
| Olver J.S., Cryan J.F., Burrows G.D. and Norman T.R.; (2000) 'Pindolol augmentation of antidepressants: a review and rationale.
'. Australian and New Zealand Journal of Psychiatry, 34 (1):71-79. [Details]
|
| Cryan J.F. and Leonard B.E.; (2000) '5-HT1A and Beyond- The role of serotonin and its receptors in depression and the antidepressant
response'. Human Psychopharmacology, 15 (2):113-135. [Details]
|
| Cryan J.F., Harkin A., Kelly J.P. and Leonard B.E.; (2000) 'Characterization of d-fenfluramine-induced hypothermia- Evidence
for multiple sites of action'. European Journal of Pharmacology, 390 (3):275-285. [Details]
|
| Healy D.G., Harkin A. Cryan J.F., Kelly J.P. and Leonard B.E.; (1999) 'Metyrapone displays antidepressant-like properties
in preclinical paradigms'. Psychopharmacology, 145 (3):303-308. [Details]
|
| Cryan J.F., McGrath C., Leonard B.E. and Norman T.R.; (1999) 'Onset of the effects of the 5-HT1A antagonist, WAY-100635, alone,
and in combination with paroxetine, on olfactory bulbectomy and 8-OH-DPAT-induced changes in the rat. '. Pharmacology Biochemistry and Behavior, 63 (2):333-338. [Details]
|
| Cryan J.F., Kelliher P., Kelly J.P. and Leonard B.E.; (1999) 'Comparative effects of serotonergic agonists with varying efficacy
at the 5-HT1A receptor on core body temperature: Modification by the selective 5-HT1A receptor antagonist WAY-100635'. Journal of Psychopharmacology, 13 (3):278-283. [Details]
|
| Cryan J.F., McGrath C., Leonard B.E. and Norman T.R.; (1998) 'Combining pindolol and paroxetine in an animal model of chronic
antidepressant action - Can early onset of action be detected?'. European Journal of Pharmacology, 352 (1):23-28. [Details]
|
| Cryan J.F., Redmond A.M., Kelly J.P. and Leonard B.E.; (1997) 'The effects of the 5-HT1A agonist flesinoxan, in three paradigms
for assessing antidepressant potential in the rat. '. European Neuropsychopharmacology, 7 (2):109-114. [Details]
|
| Cryan J.F., Redmond A.M., Kelly J.P. and Leonard B.E.; (1996) 'Does the serenic eltoprazine have antidepressant potential?
-An investigation in three rodent paradigms'. Medical Science Research, 24 (*):719-720. [Details]
|
| Lomasney KW, Cryan JF and Hyland NP (2011) Effects of the gut microbiota on colonic secretomotor function Proceedings of the British Pharmacological Society [Details]
|
| O'Leary OF, Page ME, Hirsch BR, Thomas SA, Cryan JF and Lucki I. ; (2001) Role of serotonin in the antidepressant-like effects
of SSRIs in the tail suspension test Society for Neuroscience, San Diego, California, USA [Details]
|
| O'Leary OF, Cryan JF, Page ME, Hirsch BR, Thomas SA and Lucki I; (2002) Reduced sensitivity to the behavioral and neurochemical
effects of SSRIs in norepinephrine-deficient mice Society for Neuroscience, Orlando, Florida, USA [Details]
|
| 20. O’Malley, D, Hyland, N, Julio-Pieper, M, Gosselin, R, Gibney, S, O’Mahony, S, Dinan, TG and Cryan, JF (2007) Early life
stress alters colonic CRF1 and CRF2 receptor expression in the rat Irish Society of Gastroenterology, Dublin [Details]
|
| Mahony, SO,Clarke, G,Mahony, LO,Quigley, E,Cryan, J,Dinan, TG (2007) Depressive behaviours and alterations in the immune and
stress response systems following neonatal maternal separation European College of Neuropsychopharmacology (ECNP, Vienna 2007) , pp.280-280 [Details]
|
| Gibney SM, Gosselin RD, Fitzgerald P, O’Malley D, Dinan TG and Cryan JF. (2007) Genetic influence on stress- and colonic rectal
distension-induced alterations in brain activation: Implications for the pathophysiology of irritable bowel syndrome Society for Neuroscience [Details]
|
| Gosselin RD, O'Mahony S, Gibney S, Fitzgerald P, O’Malley D, Dinan TG and Cryan JF. (2007) Altered spinal glial activation
in genetically anxious Wistar Kyoto rats: implications for visceral pain in irritable bowel syndrome (IBS) Society for Neuroscience [Details]
|
| Clarke G, Fitzgerald P, Cryan JF, Dinan TG (2008) Increased tryptophan metabolism in irritable bowel syndrome (IBS)–an immune
mediated phenomenon? Second Joint International Meeting for Neurogastroenterology and Motilit (Lucerne, Switzerland, November 2008) [Details]
|
| Clarke G, Fitzgerald P, Cryan JF, Cassidy EM,Quigley EMM, Dinan TG. (2008) Altered kynurenine pathway metabolism in Irritable
Bowel Syndrome (IBS)-Evidence of indoleamine 2,3-dioxygenase (IDO) activation in a male cohort Digestive Disease Week (San Diego, USA, May 2008) [Details]
|
| Fitzgerald P, Clarke G, Scully P, Cryan JF, Shanahan F, Quigley EMM, Cassidy EM, Dinan TG (2008) Tryptophan catabolism in
irritable bowel syndrome: Relationship to cytokines, severity and psychiatric comorbidity Digestive Disease Week (San Diego, USA, May 2008) [Details]
|
| Clarke G, Fitzgerald P, Cassidy E, Cryan JF, Quigley EM, Dinan T (2008) Increased tryptophan degradation along the kynurenine
pathway in Irritable Bowel Syndrome (IBS)-Evidence of an immune mediated indoleamine 2,3-dioxygenase (IDO) activation in a
male cohort Irish Society of Gastroenterology (Sligo, Ireland, April 2008) [Details]
|
| Clarke G, Fitzgerald P, Cryan JF, Cassidy EM,Quigley EMM, Dinan TG (2008) Tryptophan Degradation and Irritable Bowel Syndrome
(IBS)-Evidence of an immune mediated indoleamine-2,3-dioxygenase (IDO) activation in a male cohort International Neuroimmunology Symposium (University College Dublin, Dublin, Ireland, March 2008) [Details]
|
| Clarke, G,Barry, S,Scully, P,Cryan, JF,Dinan, TG (2008) Evidence of increased tryptophan degradation in psychosis: simultaneous
measurement of tryptophan and kynurenine pathway metabolites by HPLC European College of Neuropsychopharmacology (Workshop on Neuropsychopharmacology for Young Scientists in Europe, Nice, France,
March 2008) , pp.67-68 [Details]
|
| Clarke, G,O'Mahony, S,Hyland, NP,Fitzgerald, P,Dinan, TG,Cryan, JF (2008) Beta3 adrenoceptor modulation of visceral pain -
A possible role for the kynurenine pathway? European Behavioural Pharmacology Society Workshop on Behavioural Genetics and Neuropsychiatric Disorders (Cork, Ireland,
September 2008) , pp.671-672 [Details]
|
| Gibney, SM; Gosselin, RD; O’Malley, D; Dinan, TG and Cryan, JF (2008) Imaging distinct patterns of cortical brain activation
following Colorectal Distension in an animal model of irritable bowel syndrome Irish Society Gastroenterology, Sligo [Details]
|
| Gosselin, RD; Gibney, SM; O’Malley, D; Dinan, TG and Cryan, JF (2008) Region specific decrease in glial fibrillary acidic
protein (GFAP) immunoreactivity in the brain of a genetic rat model of depression Eur. Behav. Pharm. Soc, Cork [Details]
|
| O’Malley, D: Julio-Pieper, M; Dinan, T.G. and Cryan, J.F. (2008) Colo-rectal distension induces changes in expression of CRF
receptors in the CNS of WKY rats Neuroscience Ireland, Galway [Details]
|
| O’Malley, D, Julio-Pieper, M, Gosselin, RD, Dinan, TG and Cryan, JF (2008) Changes in the expression of CRF receptors in the
brain and colon following Colo-rectal distension Neurogastroenterology & Motility, Lucerne [Details]
|
| O’Malley, D, Julio-Pieper, M; Dinan, TG and Cryan, JF (2008) The effects of stress on colonic morphology in two animal models
of Irritable Bowel Syndrome Neurogastroenterology & Motility, Lucerne [Details]
|
| Hyland, NP, O’ Callaghan K, O’Malley, D, Lee, K, Dinan, TG, Cryan, JF (2008) Differential cholinergic sensitivity in the enteric
nervous system in two models of visceral hypersensitivity Neurogastroenterology & Motility, Lucerne [Details]
|
| Gibney SM, Gosselin RD, O'Malley, D, Dinan TG and Cryan JF (2008) Altered Colonic Rectal Distension-induced activation of
the prefrontal cortex in two animal models of Irritable Bowel Syndrome Neurogastroenterology & Motility, Lucerne [Details]
|
| Clarke, G, Barry, S, Scully, P, Cryan, JF, Dinan, TG; (2008) Simultaneous measurement of tryptophan and its kynurenine pathway
metabolites by HPLC: evidence of increased tryptophan degradation in psychosis EURON workshop (Bad Honnef,November 2007) , pp.67-68 [Details]
|
| O'Leary OF, O'Connor R and Cryan JF; (2009) Lithium increases hippocampal cell proliferation and alters behaviour in a high
anxiety mouse strain: Effects of chronic immobilisation stress Neuroscience Ireland Annual Conference, Dublin [Details]
|
| O'Leary OF, O'Connor R and Cryan JF; (2009) Lithium increases hippocampal cell proliferation and alters behaviour in a high
anxiety mouse strain: Effects of chronic immobilization stress European Behavioural Pharmacology Society, Rome, Italy [Details]
|
| Sweeney F, O'Leary OF and Cryan J; (2009) GABAB receptor activation during early adolescence affects adult anxiety behaviour
European Behavioural Pharmacology Society, Rome, Italy [Details]
|
| O’Malley, D; Dinan, TG and Cryan, JF. (2009) IL-6 activates neurons of the sub-mucosal plexus via a MAPK-dependent mechanism:
relevance to irritable bowel syndrome Neurogastroenterology & Motility, Chicago [Details]
|
| O’Malley, D; Dinan, TG and Cryan, JF (2009) IL-6 activates neurons in the sub-mucosal plexus via a MAPK-dependent mechanism
Irish Society for Gastroenterology, Killarney [Details]
|
| O’Malley, D; Dinan, TG and Cryan, JF (2009) IL-6 activates neurons in the sub-mucosal plexus via a MAPK-dependent mechanism
Translational Health Research Conference, UCC, Cork [Details]
|
| O’Malley, D, Julio-Pieper, M, Dinan, TG and Cryan, JF (2009) Colo-rectal distension induces changes in expression of CRF receptors
in the CNS of Wistar Kyoto rats Translational Health Research Conference, UCC, Cork [Details]
|
| Browne, CA,Clarke, G,Dinan, TG,Cryan, JF (2009) BEHAVIOURAL EFFECTS OF DIETARY TRYPOTPHAN MANIPULATIONS ON C57BL/6J AND BALB/C
MICE Neuroscience Ireland (Trinity College Dublin, September 2009) , pp.112-113 [Details]
|
| Clarke G, Fitzgerald P, Hennessy AA, Cassidy EM, Quigley EMM, Ross P, Stanton C, Cryan JF, Dinan TG. (2009) Polyunsaturated
fatty acids contribute to the inflammatory phenotype in irritable bowel syndrome Digestive Disease Week (Chicago, USA, June 2009) [Details]
|
| Browne CA, Clarke G., Dinan TG, Cryan JF (2009) Restraint stress alters tryptophan hydroxylase 2 activity in BALB/c mice:
relevance to depression European College of Neuropsychopharmacology (Workshop on Neuropsychopharmacology for Young Scientists in Europe,Nice, France,
March 2009) [Details]
|
| Bravo JA, O'Leary OF, Dinan TG and Cryan JF; (2009) Altered stress-related gene expression in the amygdala of a genetic model
of anxiety and depression Society for Neuroscience, Chicago [Details]
|
| Sweeney F, O'Leary OF and Cryan JF ; (2009) GABAB receptor activation during early adolescence affects adult anxiety behaviour
Neuroscience Ireland Annual Conference, Dublin [Details]
|
| O'Leary OF, O¿Connor RM, McGrath B and Cryan JF; (2010) Distinguishing the roles of the ventral versus dorsal hippocampus
in stress and lithium-induced changes in cell turnover Society for Neuroscience annual meeting, San Diego, CA, USA [Details]
|
| O'Leary OF, O¿Connor RM, McGrath B and Cryan JF; (2010) Lithium-induced increases in cell proliferation are restricted to
the ventral hippocampus in stressed BALB/c mice: Relationship to cell survival European Behavioural Pharmacology Society, Workshop on drugs, psychiatric disorders and neurogenesis, Tours, France [Details]
|
| Pizzo RC, O'Leary OF and Cryan JF; (2010) The medial prefrontal cortex contributes to the anxiolytic effects of the GABAB
receptor positive modulator GS39783 Neuroscience Ireland Annual Conference, University College Dublin [Details]
|
| Felice D, O'Leary OF, Sweeney F, Pizzo R and Cryan J; (2010) GABAB receptor blockade induces antidepressant-like behavioural
effects: Relationship with neurogenesis European Behavioural Pharmacology Society, Workshop on drugs, psychiatric disorders and neurogenesis, Tours, France [Details]
|
| O'Leary OF, O¿Connor RM, and Cryan JF; (2010) Lithium preferentially increases neurogenesis in the ventral but not dorsal
hippocampus of stressed BALB/c mice European College of Neuropsychopharmacology (ECNP) congress, Amsterdam, The Netherlands [Details]
|
| O'Leary OF, O¿Connor RM and Cryan JF; (2010) Desipramine differentially regulates antidepressant-like behaviour and the HPA
axis in stressed BALB/c mice 7th World Congress on Stress Leiden, The Netherlands [Details]
|
| O'Connor RM, O'Leary OF, Dinan A, Gokul A, Grenham S, Dinan TG and Cryan JF; (2010) Stress-induced Alterations in Hippocampal
and Amygdalar microRNAs: Effects of Lithium 6th Euron Workshop Drugs and the Brain: an update in Psychopharmacology, Braga, Portugal [Details]
|
| O'Connor RM, O'Leary OF, Dinan A, Gokul A, Grenham S, Dinan TG and Cryan JF; (2010) Stress-induced alterations in hippocampal
microRNAs: effects of lithium ECNP workshop on psychopharmacolgy for young scientists, Nice, France [Details]
|
| O’Malley, D; Cryan, JF; Dinan, TG. (2010) Corticotropin-Releasing Factor Sensitizes Rat Sub-Mucosal Neurons to the Effects
of IL-6 Neurogastroenterology & Motility, Boston [Details]
|
| O’Malley, D; Liston, M; Dinan, TG; Cryan, JF; Hyland, NP (2010) CRF1 receptor-dependent activation of submucosal neurones
by colonic supernatants from maternally separated rats Translational Health Research Conference, UCC, Cork [Details]
|
| O’Malley, D; Cryan, JF; Dinan, TG (2010) Corticotropin-Releasing Factor-mediated enhancement of Interleukin-6-induced activation
of Sub-Mucosal Neurons PNIRS, Dublin [Details]
|
| O’Malley, D; Liston, M; Dinan, TG; Cryan, JF; Hyland, NP. (2010) CRF1 receptor-dependent activation of submucosal neurones
by colonic supernatants from maternally separated rats DDW, New Orleans [Details]
|
| 9. Scully P, Clarke G, Grenham S, Fitzgerald P, O’Mahony CM, ,McKernan DP,Tramullas M,Shanahan F, Dinan TG, & Cryan JF (2010)
Gender-Dependent Influence of the Gut Microbiome on the Hippocampal 5-HT System Health and Medicine Research Day (Brookfield, Cork, June 2010) [Details]
|
| Scully P, Clarke G, Grenham S, Fitzgerald P, O’Mahony CM, ,McKernan DP,Tramullas M,Shanahan F, Dinan TG, & Cryan JF (2010)
Gender-Dependent Influence of the Gut Microbiome on the Hippocampal 5-HT System Psychoneuroimmunology Research Society (Trinity College, Dublin, June 2010) [Details]
|
| Julio M, O’Mahony C, Clarke G, Bravo J, Dinan TG, Cryan JF (2010) Strain-specific alterations in colon 5-HT levels correlate
to defecation responses in chronically stressed mice 7th World Congress on Stress (Leiden, Holland, August 2010) [Details]
|
| Cryan JF, Clarke G, Grenham S, Scully P, Shanahan F, Dinan TG (2010) The gut microbiome markedly influences hippocampal neurotransmission
in the mouse: Role of gender Society for Neuroscience (San Diego, USA, November 2010) [Details]
|
| Tramullas M, Clarke G, Shanahan F, Dinan TG, Cryan JF (2010) The gut microbiome alters toll-like receptor and cytokine expression
levels in the spinal cord: Role of gender Society for Neuroscience (San Diego, USA, November 2010) [Details]
|
| O’Brien FE, Clarke G, Fitzgerald P, Griffin BT, Cryan JF (2011) An integrated microdialysis model for the analysis of blood-brain
barrier drug transport in the conscious freely moving rat College of Medicine and Health Research Day (Brookfield, UCC, June 2011) [Details]
|
| O'Mahony E, O'Leary OF, McKernan DP, O¿Malley D, Dinan TG and Cryan JF ; (2011) Investigation of glycogen synthase kinase-3
as a biomarker of schizophrenia and early-life stress Health Research Board Watts Medal Competition [Details]
|
| O'Leary OF, Zandy S, Dinan TG and Cryan JF; (2011) Increased hippocampal cell proliferation as a molecular mechanism for the
therapeutic efficacy of adjunctive lithium therapy in treatment-resistant depression The International College of Neuropsychopharmacology (CINP) thematic meeting: Polypharmacy: The Good, The Bad and The Ugly,
Salzburg, Austria [Details]
|
| O'Leary OF, Zandy S, Dinan TG, Cryan JF; (2011) Adjunctive lithium treatment has antidepressant-like behavioural effects and
increases adult hippocampal neurogenesis in a mouse model of treatment resistance Anxiety and Depression, 21st Neuropharmacology Conference, Virginia, USA [Details]
|
| O'Leary OF, Savignac HM, Felice D., Bettler B., Cryan JF; (2011) GABAB(1) receptor isoforms confer differential susceptibility
to the effects of social defeat stress Anxiety and Depression, 21st Neuropharmacology Conference, Virginia, USA [Details]
|
| O'Leary OF, Zandy S, Dinan TG, and Cryan JF ; (2011) Adjunctive lithium treatment has antidepressant-like behavioural effects
and increases hippocampal neurogenesis in a model of treatment-resistant depression European Behavioural Pharmacology society, Amsterdam [Details]
|
| O'Leary OF, Zandy S, Dinan TG, and Cryan JF; (2011) Increased hippocampal cell proliferation as a molecular mechanism for
the therapeutic efficacy of adjunctive lithium therapy in treatment-resistant depression Wiring the brain: Making connections, Wicklow, Ireland [Details]
|
| O’Malley, D; Quigley, EM; Cryan, JF; Dinan, TG (2011) Plasma derived from patients with irritable bowel syndrome excites rat
submucosal neurons via IL-6 and CRFR1 dependent mechanisms DDW, Chicago [Details]
|
| Felice D, O'Leary OF, Pizzo RC, Cryan JF; (2011) Adult hippocampal neurogenesis is increased by a GABAB receptor antagonist
: Relevance to antidepressant action Neuropharmacology Conference, Virginia, USA, November 10-11 [Details]
|
| Felice D, O'Leary OF, Bettler B, Cryan JF; (2011) The role of GABAB(1) receptor subunits in the modulation of early life stress
on anxiety and depression-related behaviour in adulthood Anxiety and Depression, 21st Neuropharmacology Conference, Virginia, USA [Details]
|
| Kennedy PJ, Clarke G, O’Neill A, Groeger JA, Quigley EM, Shanahan F , Cryan JF, Dinan TG (2012) An assessment of cognitive
function in irritable bowel syndrome (IBS): Are deficits in episodic memory stress-related and mediated by tryptophan metabolism
along the kynurenine pathway? Digestive Disease Week (San Diego, USA, May 2012) [Details]
|
| Clarke G, Grenham S, Scully P, Fitzgerald P, Shanahan F, Dinan TG, Cryan JF (2012) Regulation of Serotonergic Neurotransmission
and Behaviour by the Brain-Gut-Microbiome Axis Digestive Disease Week (San Diego, USA, May 2012) [Details]
|
| Felice D, O’Leary O.F, Bettler B, Cryan JF (2012) GABAB(1) Receptor Subunit Isoforms Differentially Mediate Susceptibility
to Depression-Related Behaviour Following Early-Life Stress ECNP Workshop on Neuropsychopharmacology, March 15-18 2012, Nice, France [Details]
|
| O'Malley, D; Liston, M; Dinan, TG; Cryan, JF; Hyland, NP; (2010) CRF1 receptor-dependent activation of submucosal neurones
by colonic supernatants from maternally separated rats Gastroenterology [Details]
|
| Godinho, BMDC; O'Mahony, AM; Ogier, JR; Darcy, R; O'Driscoll, CM; Cryan, JF; (2010) Cyclodextrins as nonviral-vectors for
siRNA delivery to the central nervous system Neuroscience Ireland Annual Conference 2010 [Details]
|
| O'Mahony, A; Ogier, J; Doyle, D; Darcy, R; Cryan, JF; O'Driscoll, CM; (2010) Modified cyclodextrins as siRNA delivery vectors
for neuronal and non-neuronal cells: A study of different structural modifications All-Ireland School of Pharmacy Conference. Queens University, Belfast [Details]
|
| OMahony SM; Savignac HM; O'Brien T; Scully P; Quigley EM; Marchesi, J; O'Toole, PW; Dinan TG; Cryan JF; (2010) Early-life
Dysbiosis-Induced Visceral Hypersensitivity in Adulthood Gastroenterology [Details]
|
| O'Mahony, AM; Ogier, J; O'Neill, M; Darcy, R; Cryan, JF; O'Driscoll, CM; (2010) Cyclodextrin-based vectors for siRNA delivery:
Effects of pegylation on physical and biological properties in vitro American Association of Pharmaceutical Scientists (AAPS) Annual Conference [Details]
|
| Julio-Pieper M, Hyland NP, Cryan JF, Dinan TG; (2009) Group-III Metabotropic Glutamate Receptors Are Expressed in Rodent Colon:
A Role in Cholinergically Induced Electrolyte Secretion Gastroenterology [Details]
|
| Hyland NP, Bongiovanni C, O'Mahony CM, Fitzgerald P, Dinan TG, Cryan JF; (2009) The Combined Effects of Neonatal Psychological
Stress and An Anxious Phenotype On Visceral Hypersensitivity and Colonic Function in Rats Gastroenterology [Details]
|
| Hyland NP, Bongiovanni C, O¿Mahony SM, Fitzgerald P, Dinan TG, Cryan JF; (2009) The combined effects of neonatal psychological
stress and an anxious phenotype on visceral hypersensitivity and colonic function in rats Neurogastroenterology and Motility [Details]
|
| O' Mahony SM, Fitzgerald P, O¿ Sullivan B, Dinan TG, Cryan JF; (2009) Aberrant behavioural and physiological responses to
a systemic immune challenge in the wistar kyoto rat Neuroscience [Details]
|
| McKernan DP, Nolan A, O'Mahony SM, Hyland NP, Brint E, Dinan TG, Cryan JF.; (2009) Toll-Like Receptor mRNA Expression Is Selectively
Increased in the Colonic Mucosa of Two Animal Models of Chronic Stress: Relevance to Irritable Bowel Syndrome Gastroenterology (DDW) [Details]
|
| Clarke G, O¿ Mahony SM, Hyland NP, Fitzgerald P, Cryan JF, Dinan TG. ; (2008) Visceral pain and beta3 adrenoceptor modulation
a role for the kynurenine pathway? Neurogastroenterology Motility , pp.1-159 [Details]
|
| Hyland NP, Gibney SM, Gosselin RD, Lee K, Dinan TG, Cryan JF. ; (2008) Assessment of colonic secretory function and faecal
output in viscerally hypersensitive Wistar Kyoto rats Gastroenterology [Details]
|
| Hyland NP, O¿ Callaghan K, O¿Malley D, Lee K, Dinan TG, Cryan JF. ; (2008) Differential cholinergic sensitivity in the enteric
nervous system in two models of visceral hypersensitivity Neurogastroenterology Motility , pp.1-159 [Details]
|
| Hyland NP, O¿Mahony SM, Bulmer DC, Julio-Pieper M, Bongiovanni C, Dinan TG, Cryan JF. ; (2008) Beta3-adrenoceptor mediated
secretion and localisation in the submucosal plexus of descending colon from maternally separated animals Neurogastroenterology Motility , pp.1-159 [Details]
|
| ¿ O'Mahony SM, Coelho AM, Bulmer DC, Fitzgerald P, Bongiovanni C, Winchester W, Lee K, Dinan TG, Cryan JF; (2008) Central
5-HT2B Receptors Modulate Visceral Hypersensitivity in a Genetic Model of Irritable Bowel Syndrome Neurogastroenterology and Motility [Details]
|
| Coelho AM, O'Mahony SM, Taylor CM, Wheeldon A, Fitzgerald P, Dinan TG, Cryan JF, Lee K, Winchester WJ. ; (2008) reverses colorectal
distension-induced visceral pain behaviours in rat models of acute and chronic visceral hypersensitivity Gastroenterology [Details]
|
| Clarke G, Mahony SM, Hyland NP, Fitzgerald P, Cryan JF, Dinan TG; (2008) Visceral pain and beta3 adrenoceptor modulation a
role for the kynurenine pathway? Neurogastroenterology and Motility (NGM, Lucerne 2008) [Details]
|
| ¿ Bulmer DC, O'Mahony SM, Coelho AM, Gray K, Taylor C, Dinan TG, Cryan JF, Lee K, Winchester WJ; (2008) Analgesic effects
of 5-HT2B antagonists in pre-clinical models of colorectal pain Gastroenterology (DDW) [Details]
|
| Hyland NP, O¿Mahony SM, Bulmer DC, Lee K, Dinan TG, Cryan JF.; (2008) Do mast cells contribute to visceral hypersensitivity
in adult rats following neonatal psychological stress? Gastroenterology , pp.A552-553 [Details]
|
| Mahony SM, Clarke G, Mahony L, Quigley EMM, Cryan JF, Dinan TG. (2007) Depressive behaviours and alterations in the immune
and stress response systems following neonatal maternal separation Neuropsychopharmacology [Details]
|
| Thakker DR, Natt F, Husken D, Maier R, Muller M, van der Putten H, Hoyer D, Cryan JF; (2004) Neurochemical and behavioral consequences of widespread gene knockdown in the adult mouse brain by using nonviral RNA interference , pp.17270-17275 [Details]
|
| Cryan, JF,Julio-Pieper, M (2011) Metabotropic Glutamate Receptors in Peripheral and Non-Neural Tissues: Implications for Drug Discovery. Abstract [Details]
|
| Connor, RMO,Pusceddu, M,Dinan, TG,Cryan, JF (2011) Impact of Early-Life Stress on Group III mGlu receptor levels in the rat Hippocampus: Effects of ketamine, Electroconvulsive
Shock Therapy and Fluoxetine Treatment. Abstract [Details]
|
| Cryan, JF,O'Connor, RM (2011) MGLUR7: A THERAPEUTIC TARGET AT THE INTERFACE OF COGNITION AND EMOTION. Abstract [Details]
|
| O'Leary, OF,Zandy, S,Dinan, TG,Cryan, JF (2011) ADJUNCTIVE LITHIUM TREATMENT HAS ANTIDEPRESSANT-LIKE BEHAVIOURAL EFFECTS AND INCREASES HIPPOCAMPAL NEUROGENESIS IN A MODEL
OF TREATMENT-RESISTANT DEPRESSION. Abstract [Details]
|
| Connor, RMO,Dinan, TG,Cryan, JF (2011) miRNAS AS NOVEL ANTIDEPRESSANT TARGETS: CONVERGING EFFECTS OF ACUTE KETAMINE, ELECTROCONVULSIVE SHOCK THERAPY AND CHRONIC
FLUOXETINE TREATMENTS. Abstract [Details]
|
| Jacobson, LH,Neijt, HC,Bettler, B,Kaupmann, K,Cryan, JF (2006) Molecular dissection of the role of GABA(B1) receptor isoforms 1a and 1b in anxiety-related behaviour. Abstract [Details]
|
| Slattery, DA,Cryan, JF (2006) The infralimbic cortex modulates stress-induced coping behaviour - implications for depression. Abstract [Details]
|
| Slattery, DA,Markou, A,Cryan, JF (2006) Evaluation of reward processes in an animal model of depression. Abstract [Details]
|
| Cryan, JF,Thakker, DR,van der Putten, H,Flor, PJ,Hoyer, D (2006) Emerging use of RNA interference to understand the role of genes in anxiety. Abstract [Details]
|
| Slattery, DA,Markou, A,Cryan, JF (2006) Evaluation of reward processes in an animal model of depression. Abstract [Details]
|
| Jacobson, LH,Neijt, HC,Bettler, B,Kaupmann, K,Cryan, JF (2006) Molecular dissection of the role of GABA1 receptor isoforms 1a and 1b in anxiety-related behaviour. Abstract [Details]
|
| Mahony, CMO,Sweeney, F,Daly, E,Dinan, TG,Cryan, JF (2007) Assessing the genetic influence on anxiety behaviour and stress-induced brain activation in the mouse. Abstract [Details]
|
| Bravo, JA,Dinan, TG,Cryan, JF (2008) The effects of acetylcholinesterase inhibitor pyridostigmine on inflammatory responses in an animal model of irritable bowel
syndrome. Abstract [Details]
|
| Clarkc, G,Fitzgerald, P,Cryan, JF,Dinan, TG (2008) Tryptophan Degradation and Irritable Bowel Syndrome (IBS) - Evidence of an immune mediated indoleamine-2,3-dioxygenase (IDO)
activation in a male cohort. Abstract [Details]
|
| O'Connor, RM,McKernan, DR,Browne, C,Dinan, TG,Cryan, JF (2008) Genetic influences on hippocampal susceptibility to cell death following immune activation. Abstract [Details]
|
| Browne, CA,O'Brien, F,Connor, TJ,Cryan, JF (2008) Aberrant cytokine response to stress in BALB/c mice after lipopolysaccharide (LPS) challenge: relevance of tryptophan hydroxylase
2. Abstract [Details]
|
| Browne, CA,O'Brien, F,Connor, TJ,Dinan, TG,Cryan, JF (2008) Aberrant LPS-induced cytokine responses in mice following stress: Relevance to major depression. Abstract [Details]
|
| Cryan, J (2008) Genetic and pharmacological tools to unravel the role of mGluR7 in stress-related disorders. Abstract [Details]
|
| Gosselin, RD,Gibney, S,O'Malley, D,Dinan, TG,Cryan, JF (2008) Region specific decrease in glial fibrillary acidic protein (GFAP) immunoreactivity in the brain of a genetic rat model of
depression. Abstract [Details]
|
| Hoyer, D,Thakker, DR,Natt, F,Maier, R,Huesken, D,Mueller, M,Flor, PJ,van der Putten, H,Schmutz, M,Cryan, JF (2008) Gobal down-regulation of gene expression in the brain using RNA interference, with emphasis on neuropeptides, GPCRS and monoamine
transporters. Abstract [Details]
|
| O'Mahony, CM,Bravo, J,Dinan, TG,Cryan, JF (2008) Differential expression of mGluR7 in two animal models of depression. Abstract [Details]
|
| O'Mahony, CM,Dinan, TG,Cryan, JF (2008) The effects of acute and chronic stress on mGluR7 and BDNF gene expression in two inbred strains of mice which differ in emotionality. Abstract [Details]
|
| Bravo, JA,Dinan, TG,Cryan, JF (2008) Altered stress-related gene expression in the hippocampus of a gentetic model of anxiety & depression. Abstract [Details]
|
| Browne, CA,O'Brien, F,Connor, TJ,Dinan, TG,Cryan, JF (2008) BALB/c mice as a model of aberrant stress-induced cytokine expression: Relevence to major depression. Abstract [Details]
|
| Gibney, SM,Gosselin, RD,Dinan, TG,Cryan, JF (2008) Differential activation of the prefrontal cortex in response to stress and colonic rectal distension in a genetically susceptible
model of depression & irritable bowel syndrome (IBS). Abstract [Details]
|
| O'Mahony, C,Dinan, TG,Cryan, JF (2009) Altered expression of hippocampal mGLUR7 mRNA in a model of depression. Abstract [Details]
|
| Savignac, HM,Dinan, TG,Cryan, JF (2009) Mice are resistant to early-life stress-induced alterations in adult behaviour. Abstract [Details]
|
| O'Connor, RM,O'Leary, OF,Dinan, A,Grenham, S,Dinan, TG,Cryan, JF (2010) Stress-induced alterations in hippocampal microRNAs: effects of lithium. Abstract [Details]
|
| O'Connor, RM,O'Leary, OF,Dinan, A,Gokul, A,Dinan, TG,Cryan, JF (2010) Stress-induced alterations in hippocampal and amygdalar microRNAs: effects of lithium. Abstract [Details]
|
| Cryan, J,Bravo, JA,Clarke, G,Hyland, NP,O'Malley, D,O'Mahony, D,Julio-Pieper, M,McKernan, DP,Tramullas, M,Dinan, TG (2010)
Animal models of co-morbid depression and irritable bowel syndrome. Abstract [Details]
|
| Schellekens, H,Dinan, TO,Cryan, JF (2010) Increased serotonin 2c receptor editing in a mouse model of obesity. Abstract [Details]
|
| O'Leary, OF,O'Connor, RM,Cryan, JF (2010) Lithium preferentially increases neurogenesis in the ventral but not dorsal hippocampus of stressed BALB/c mice. Abstract [Details]
|
| Julio-Pieper, M,Hyland, NP,Bravo, JA,Dinan, TG,Cryan, JF (2010) Peripheral metabotropic glutamate receptors: focus on the role of mGluR7 in brain-gut axis regulation. Abstract [Details]
|
| O'Leary, OF,O'Connor, RM,McGrath, B,Cryan, JF (2010) LITHIUM-INDUCED INCREASES IN CELL PROLIFERATION ARE RESTRICTED TO THE VENTRAL HIPPOCAMPUS IN STRESSED BALB/C MICE: RELATIONSHIP
TO CELL SURVIVAL. Abstract [Details]
|
| Felice, D,O'Leary, OF,Sweeney, FF,Pizzo, RC,Cryan, JF (2010) GABAB RECEPTOR BLOCKADE INDUCES ANTIDEPRESSANT-LIKE BEHAVIOURAL EFFECTS: RELATIONSHIP WITH NEUROGENESIS. Abstract [Details]
|
| McKernan, DP,Bongiovanni, C,Fitzgerald, P,Dinan, TG,Cryan, JF (2010) BIFIDOBACTERIUM INFANTIS 35624 REDUCES VISCERAL HYPERACTIVITY IN A RAT MODEL OF CHRONIC STRESS. Abstract [Details]
|
| O'Leary, OF,O'Connor, RM,Cryan, JF (2010) LITHIUM INCREASES HIPPOCAMPAL CELL PROLIFERATION AND ALTERS BEHAVIOUR IN A HIGH ANXIETY MOUSE STRAIN: EFFECTS OF CHRONIC IMMOBILISATION
STRESS. Abstract [Details]
|
| Pizzo, RC,Cucinotta, AL,Cryan, JF (2010) Neural circuitry underlying GABA-B receptor positive modulator-induced effects on anxiety behaviour in the mouse. Abstract [Details]
|
| Sweeney, FF,O'Leary, OF,Cryan, JF (2010) GABA(B) RECEPTOR ACTIVATION DURING EARLY ADOLESCENCE AFFECTS ADULT ANXIETY BEHAVIOUR. Abstract [Details]
|
| O'Mahony, SM,Fitzgerald, P,O'Sullivan, B,Dinan, TG,Cryan, JF (2010) ABERRANT BEHAVIOURAL AND PHYSIOLOGICAL RESPONSES TO A SYSTEMIC IMMUNE CHALLENGE IN THE WISTAR KYOTO RAT. Abstract [Details]
|
| McKernan, DP,Dennison, U,Cryan, JF,Dinan, TG (2011) ALTERED TOLL-LIKE RECEPTOR RESPONSES IN SCHIZOPHRENIA AND BIPOLAR DISORDER PATIENTS. Abstract [Details]
|
| O'Connor, RM,Savignac, HM,Finger, BC,Dinan, TG,Cryan, JF (2011) CHRONIC SOCIAL DEFEAT STRESS INDUCES DIFFERENTIAL CHANGES IN HIPPOCAMPAL MICRORNA EXPRESSION IN TWO INBRED MOUSE STRAINS DIFFERING
IN ANXIETY BEHAVIOUR. Abstract [Details]
|
| Pizzo, RC,O'Leary, OF,Cryan, JF (2011) THE MEDIAL PREFRONTAL CORTEX CONTRIBUTES TO THE ANXIOLYTIC EFFECTS OF THE GABA(B) RECEPTOR POSITIVE MODULATOR GS39783. Abstract [Details]
|
| Finger, BC,Dinan, TG,Cryan, JF (2011) THE UTILITY OF LEPTIN-DEFICIENT MICE FOR STUDYING THE EFFECTS OF GHRELIN RECEPTOR AGONISTS AND ANTAGONISTS ON FOOD INTAKE. Abstract [Details]
|
| Godinho, BMDC,O'Mahony, AM,Ogier, JR,Darcy, R,O'Driscoll, CM,Cryan, JF (2011) CYCLODEXTRINS AS NONVIRAL-VECTORS FOR siRNA DELIVERY TO THE CENTRAL NERVOUS SYSTEM. Abstract [Details]
|
| Browne, CA,Clarke, G,Dinan, TG,Cryan, JF (2011) DIFFERENTIAL STRESS-INDUCED ALTERATIONS OF THE SEROTONERGIC SYSTEM OF TWO INBRED MOUSE STRAINS, BALB/C AND C57BL/6 J MICE,
WHICH DIFFER IN FUNCTIONAL POLYMORPHISMS OF THE TPH2 GENE. Abstract [Details]
|
| Schellekens, H,Davey, KJ,O'Mahony, SM,Dinan, TG,Cryan, JF (2011) Olanzapine-induced weight gain is associated with increased hypothalamic ghrelin receptor expression. Abstract [Details]
|
| Finger, BC,Dinan, TG,Cryan, JF (2011) LEPTIN-DEFICIENT MICE RETAIN NORMAL APPETITIVE SPATIAL AND OPERANT LEARNING YET EXHIBIT MARKED INCREASES IN ANXIETY-RELATED
BEHAVIOURS. Abstract [Details]
|
| Tramullas, M,Dinan, TG,Cryan, JF (2011) SPINAL TOLL-LIKE RECEPTOR mRNA EXPRESSION IS SELECTIVELY INCREASED IN AN ANIMAL MODEL OF VISCERAL PAIN: RELEVANCE TO IRRITABLE
BOWEL SYNDROME. Abstract [Details]
|
| Hoyer, D,Thakker, DR,Natt, F,Maier, R,Huesken, D,Muller, M,Flor, P,van der Putten, H,Schmutz, M,Bilbe, G,Cryan, JF (2006)
Global down-regulation of gene expression in the brain using RNA interference, with emphasis on monoamine transporters and
GPCRs: Implications for target characterization in psychiatric and neurological disorders. Other [DOI] [Details]
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| Cryan, JF,Thakker, DR,Hoyer, D (2007) Emerging use of non-viral RNA interference in the brain. Other [Details]
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| Cryan, JF,Bravo, JA,Dinan, TG,Forsythe, P,Bienenstock, J (2012) Reply to McLean et al. and Burnet: The microbiome-gut-brain axis as a pathway toward next generation psychotropics. Other [DOI] [Details]
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| Cryan J.F., McGrath C., Leonard B.E. and Norman T.R.; (1997) The effects of paroxetine and pindolol in combination, on 8-OH-DPAT-induced hypothermia in the rat. Other [Details]
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| Cryan J.F., McGrath C., Leonard B.E., Burrows G.D. and Norman T.R.; (1998) Combining pindolol and paroxetine in an animal model of chronic antidepressant action - Can early onset of action be detected?. Other [Details]
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| Cryan J.F., Redmond A.M., Kelly J.P. and Leonard B.E.; (1998) Does the 5-HT1A receptor agonist flesinoxan and the serenic eltoprazine have antidepressant potential? An investigation in
three rodent paradigms. Other [Details]
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| Cryan J.F., McGrath C., Leonard B.E., Burrows G.D. and Norman T.R.; (1998) The effects of melatonin and melatonin receptor ligands in the rat forced swim test. Other [Details]
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| Cryan J.F. and Lucki I.; (1999) Reboxetine, a selective norepinephrine reuptake inhibitor, alters active behaviors in a modified rat forced swim test. Other [Details]
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| Harkin A., Naughton M., Cryan J.F., Kelly J.P., and Leonard B.E.; (1999) Differential modification of d-fenfluramine-induced serotonergic responses by acute sertraline and fluoxetine administration
to rats. Other [Details]
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| Cryan J.F. and Lucki I.; (2000) Postsynaptic Serotonin Receptors Involved in the Antidepressant-Like effects of fluoxetine: Evidence for a Role of 5-HT2C
but not 5-HT4 receptors. Other [Details]
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| Lucki I., Page M.E. and Cryan J.F.; (2000) Noradrenergic lesions differentially alter the antidepressant -like effects of reboxetine. Other [Details]
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| Kirby L.G., Cryan J.F., Bello N., Lucki I. and Valentino R.J.; (2000) Localization of corticotropin-releasing factor binding sites on serotonergic processes in the raphe nucleus: effects of 5,7
dihydroxytryptamine. Other [Details]
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| Cryan J.F., Page M.E and Lucki I.; (2000) The impact of noradrenergic lesions on the antidepressant-like effects of reboxetine. Other [Details]
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| Cryan J.F. and Lucki I.; (2000) Antidepressant-like behavioral effects mediated by the 5-HT2C receptor. Other [Details]
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| Cryan J.F., Skjei K.S. and Markou A.; (2001) The antidepressant bupropion increases brain reward function: reversal of reward deficits associated with nicotine withdrawal. Other [Details]
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| O'Leary O.F., Page M.E., Hirsch B.R., Cryan J.F., Thomas S.A. and Lucki I.; (2001) Role of serotonin in the antidepressant-like effects of SSRIs in the tail suspension test. Other [Details]
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| Kirby L.G. Cryan J.F., Page M.E., Bello N.T., Kung M-P., Kung H.F., Lucki I and Valentino R.J.; (2001) Substantial reduction in corticotropin-releasing factor (CRF) binding sites in the dorsal raphe nucleus (drn) of rats administered
5,7-dihydroxytryptamine (5,7-DHT). Other [Details]
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| Cryan J.F., Dalvi A., Lucki I. and Thomas S.A.; (2001) Dopamine-B-hydroxylase deficient mice as a tool to assess the role of norepinephrine in the mechanism of action of antidepressant
drugs. Other [Details]
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| Cryan J.F., Hirsch B.R., Jin S-H, Lucki I. and Thomas S.A.; (2001) Reduced sensitivity to the antidepressant-like effects of SSRIs in dopamine-ƒÒ-hydroxylase deficient mice. Other [Details]
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| Cryan J.F, Bruijnzeel A.W, Skjei K.S and Markou A; (2002) The antidepressant bupropion enhances brain reward function and reverses nicotine withdrawal in the rat. Other [Details]
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| Page M.E., Szeliga P.J., Gasparini F. and Cryan J.F.; (2002) Neurochemical and behavioral assays support an anxiolytic-like profile for 2-methyl-6-(phenylethynyl)pyridine (MPEP), a metabotropic
glutamate receptor 5 (mGluR5) antagonist. Other [Details]
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| O'Leary O.L. Cryan J.F., Page M.E., Thomas S.A. and Lucki I.; (2002) Reduced sensitivity to the behavioral and neurochemical effects of SSRIs in norepinephrine-deficient mice. Other [Details]
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| Cryan J.F., Kelly P.H., Sansig G., Flor P.J. and van Der Putten H.; (2003) Antidepressant and anxiolytic-like effects in mice lacking the group III metabotropic glutamate receptor mGluR7. Other [Details]
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| Cryan J.F. Mombereau C., Sansig G., van der Putten H. and Kaupmann K.; (2003) GABAB receptors play a key role in the modulation of anxiety and depression-related behaviours: Evidence from GABAB(1) receptor
deficient mice. Other [Details]
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| Cryan J.F., Szeliga P.J., Gasparini F., Page M.E.; (2003) Potential anxiolytic-like actions of metabotropic glutamate receptor 5 (mGluR5) antagonists revealed by neurochemical and
behavioral studies. Other [Details]
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| Gentsch C., Cryan J.F., Gasparini F., Vassout A., Spooren W.; (2003) mGluR5 receptor antagonists, future anxiolytics?. Other [Details]
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| Mombereau C., Kaupmann K., Sansig G., van der Putten H. And Cryan J.F.; (2003) GABAB receptors play a key role in the modulation of anxiety and depression-related behaviours. Other [Details]
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| Kaupmann, K., Cryan, J.F., Wellendorph, P. Mombereau, C. Sansig, G. Klebs, K., Schmutz, M., Froestl, W. van der Putten, H.,
Mosbacher, J., Bräuner-Osborne, H., Waldmeier, P., and Bettler, B.; (2003) Effects of yƒ{hydroxybutyrate in GABA-B receptor deficient mice. Other [Details]
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| Mombereau C., Kuntzelmann G., Loetscher E., Cryan J.F.; (2004) Chronic antidepressants and GABAB receptor ligands counteract Handling-Stress induced downregulation of 5-HT1A Receptor mRNA
In the hippocampus Of Balb/C Mice. Other [Details]
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| Kaupmann K., Lhuillier L., Mombereau C., Slattery D.A., Dupuis D.S., and Cryan J.F.; (2004) Novel pharmacological agents modulating GABAB receptor function: Potential therapeutics for nicotine dependence. Other [Details]
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| Mombereau C., Kaupmann K., Froestl W., Van Der Putten H. and Cryan, J.F.; (2004) GABAB Receptors Play a Key Role in the Modulation of Anxiety and Antidepressant-Related Behaviour: Genetic And Pharmacological
Evidence. Other [Details]
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| Gassmann M., Vigot R., Shaban H., Barbieri S., Brauner-Osborne H., Thi A.L., Cryan J.F., Kaupmann K. and Bettler B.; (2004)
Genetic dissection of GABAB receptor function in mice. Other [Details]
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| Dupuis D.S., Relkovic D., Cryan J.F., Kaupmann K.; (2004) Mapping of the binding Site of the GABAB positive modulator GS39783 by use of interspecies Rat/Drosophila Subunit Combinations. Other [Details]
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| Thakker D.R., Natt F., Maier R., Muller M., Van Der Putten H., Hoyer D., Cryan, J.F.; (2004) Global Down-Regulation Of Gene Expression In The Brain Using RNA Interference: Implications For Target Characterization In
Psychiatric And Neurological Disorders. Other [Details]
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| Russig H., Ruedi-Bettschen D., Feldon J., Wrynn A., Cryan J.F., Pryce C.R.; (2004) Early deprivation leads to reduced motivation for reward that can be restored with fluoxetine in adult wistar rats. Other [Details]
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| Slattery D.A., Desrayaud S., Cryan J.F.; (2004) GABAB Receptor-Mediated Antidepressant-Like Behaviour Is Serotonin Dependent. Other [Details]
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| L.H. Jacobson, Cryan, J.F.; (2004) Altered sensitivity to the pharmacological effects of the GABAB receptor agonist baclofen in different mouse strains. Other [Details]
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| Urwyler S., Cryan J.F., Dupuis D.S., Gjoni T., Lingenhoehl K., Mombereau C., Mosbacher J., Pozza M.F. and Kaupmann K.; (2004)
Positive Allosteric Modulation of ƒ×-Aminobutyric AcidB Receptors. Other [Details]
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| Pun S., Osinde M., Stoehr N., Senechal Y., Schade A., Cryan J.F., Dev K.K.; (2005) Lentiviral vector-mediated transgene expression in vitro and in vivo neuronal models. Other [Details]
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| Thakker D.R., Natt F., Hüsken D., Muller M., Maier R., van der Putten H., Hoyer D., Cryan, J.F.; (2005) Behavioural and neurochemical consequences of siRNA-induced knockdown of serotonin and dopamine transporters in the adult
mouse brain: Implications for validation of novel therapeutic targets for psychiatric illnesses. Other [Details]
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| Bissiere, S. Neijt H.C., Lecourtier L., Olpe H.R., Cryan J.F.; (2005) A role for the anterior cingulate cortex in amygdala-dependent fear processes: behavioral studies in the rat. Other [Details]
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| Lhuillier L., Mombereau C., Cryan J.F., Kaupmann K.; (2005) Investigation of the molecular markers underlying the anti-addictive effects of GABAB receptor agonists and positive modulators. Other [Details]
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| Thakker D.R., Natt F., Hüsken D., Maier R., van der Putten H., Hoyer D., Cryan J.F.; (2005) Behavioural and neurochemical consequences of siRNA-induced knockdown of serotonin and dopamine transporters in the adult
mouse brain: Implications for validation of novel antidepressant targets. Other [Details]
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| Slattery D.A., Mombereau C., Froestl W., Markou A., Kaupmann K. and Cryan, J.F.; (2005) GABAB receptor positive modulation as a novel therapeutic approach to drug dependence: Blockade of the rewarding and psychostimulant
effects of cocaine. Other [Details]
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| Slattery, DA, Markou, A, Cryan, JF; (2006) Evaluation of Reward Processes In An Animal Model of Depression. Other [Details]
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| Slattery, DA, Cryan, JF, Markou, A; (2006) Evaluation of Reward Processes In An Animal Model of Depression. Other [Details]
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| Cryan, JF, Thakker, DR, van der Putten, H, Flor, PJ, Hoyer, D; (2006) Emerging Use of Rna Interference to Understand The Role of Genes In Anxiety. Other [Details]
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| Jacobson, LH, Neijt, HC, Bettler, B, Kaupmann, K, Cryan, JF; (2006) Molecular Dissection of The Role of Gaba1 Receptor Isoforms 1a and 1b In Anxiety-Related Behaviour. Other [Details]
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| Slattery, DA, Cryan, JF; (2006) The Infralimbic Cortex Modulates Stress-Induced Coping Behaviour - Implications For Depression. Other [Details]
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| Hoyer, D, Thakker, DR, Natt, F, Maier, R, Huesken, D, Muller, M, Flor, P, van der Putten, H, Schmutz, M, Bilbe, G, Cryan,
JF; (2006) Global Down-Regulation of Gene Expression In The Brain Using Rna Interference, With Emphasis On Monoamine Transporters and
Gpcrs: Implications For Target Characterization In Psychiatric and Neurological Disorders. Other [DOI] [Details]
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| Mahony, CMO, Sweeney, F, Daly, E, Dinan, TG, Cryan, JF; (2007) Assessing The Genetic Influence On Anxiety Behaviour and Stress-Induced Brain Activation In The Mouse. Other [Details]
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| Mahony, SO, Clarke, G, Mahony, LO, Quigley, E, Cryan, J, Dinan, T; (2007) Depressive Behaviours and Alterations In The Immune and Stress Response Systems Following Neonatal Maternal Separation. Other [Details]
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| O'Mahony, CM, Bravo, J, Dinan, TG, Cryan, JF; (2008) Differential Expression of Mglur7 In Two Animal Models of Depression. Other [Details]
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| Browne, CA, O'Brien, F, Connor, TJ, Dinan, TG, Cryan, JF; (2008) Aberrant Lps-Induced Cytokine Responses In Mice Following Stress: Relevance to Major Depression. Other [Details]
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| O'Connor, RM, McKernan, DR, Browne, C, Dinan, TG, Cryan, JF; (2008) Genetic Influences On Hippocampal Susceptibility to Cell Death Following Immune Activation. Other [Details]
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| Bravo, JA, Dinan, TG, Cryan, JF; (2008) The Effects of Acetylcholinesterase Inhibitor Pyridostigmine On Inflammatory Responses In An Animal Model of Irritable Bowel
Syndrome. Other [Details]
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| Hoyer, D, Thakker, DR, Natt, F, Maier, R, Huesken, D, Mueller, M, Flor, PJ, van der Putten, H, Schmutz, M, Cryan, JF; (2008)
Gobal Down-Regulation of Gene Expression In The Brain Using Rna Interference, With Emphasis On Neuropeptides, Gpcrs and Monoamine
Transporters. Other [Details]
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| Browne, CA, O'Brien, F, Connor, TJ, Cryan, JF; (2008) Aberrant Cytokine Response to Stress In Balb/C Mice After Lipopolysaccharide (Lps) Challenge: Relevance of Tryptophan Hydroxylase
2. Other [Details]
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| O'Mahony, CM, Dinan, TG, Cryan, JF; (2008) The Effects of Acute and Chronic Stress On Mglur7 and Bdnf Gene Expression In Two Inbred Strains of Mice Which Differ In Emotionality. Other [Details]
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| Bravo, JA, Dinan, TG, Cryan, JF; (2008) Altered Stress-Related Gene Expression In The Hippocampus of A Gentetic Model of Anxiety & Depression. Other [Details]
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| Browne, CA, O'Brien, F, Connor, TJ, Dinan, TG, Cryan, JF; (2008) Balb/C Mice As A Model of Aberrant Stress-Induced Cytokine Expression: Relevence to Major Depression. Other [Details]
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| Gibney, SM, Gosselin, RD, Dinan, TG, Cryan, JF; (2008) Differential Activation of The Prefrontal Cortex In Response to Stress and Colonic Rectal Distension In A Genetically Susceptible
Model of Depression & Irritable Bowel Syndrome (Ibs). Other [Details]
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| Gosselin, RD, Gibney, S, O'Malley, D, Dinan, TG, Cryan, JF; (2008) Region Specific Decrease In Glial Fibrillary Acidic Protein (Gfap) Immunoreactivity In The Brain of A Genetic Rat Model of
Depression. Other [Details]
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| Clarkc, G, Fitzgerald, P, Cryan, JF, Dinan, TG; (2008) Tryptophan Degradation and Irritable Bowel Syndrome (Ibs) - Evidence of An Immune Mediated Indoleamine-2,3-Dioxygenase (Ido)
Activation In A Male Cohort. Other [Details]
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| Hyland, NP,Julio-Pieper, M,O'Mahony, SM,Bulmer, DC,Lee, K,Quigley, EM,Dinan, TG,Cryan, JF (2009) A distinct subset of submucosal mast cells undergoes hyperplasia following neonatal maternal separation: a role in visceral
hypersensitivity?. Other [DOI] [Details]
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| O'Mahony, C, Dinan, TG, Cryan, JF; (2009) Altered Expression of Hippocampal Mglur7 Mrna In A Model of Depression. Other [Details]
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| Savignac, HM, Dinan, TG, Cryan, JF; (2009) Mice Are Resistant to Early-Life Stress-Induced Alterations In Adult Behaviour. Other [Details]
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