Research in Professor Nolan's laboratory focuses on the effects of inflammation, exercise, stress and diet on hippocampal plasticity and neurogenesis (the birth of new neurons) and on associated learning, memory and mood throughout the lifespan. To date she has supervised >30 PhD/MSc/postdoctoral researchers/to completion and has also supervised numerous visiting and undergraduate students. She was awarded UCC’s Research Supervisor of the Year Award, 2016. She has a number of collaborations with academic and industrial partners and her team have had recognition for research in the form of prizes, image exhibition and media coverage. She has published >80 full-length journal articles and >150 conference abstracts. Her H-index is 37 (Google Scholar) and her work has been cited >5500 times. She has secured ~€5.5M in research funding as Lead Investigator from Science Foundation Ireland, Marigot Ireland Ltd, Molecular Medicine Ireland, Irish Research Council, Weston Trust, and Vasogen Inc., Canada. She was consortium lead on a European Centres of Excellence in Neurodegeneration (COEN) project.
Yvonne is Vice Dean of Graduate Studies in the College of Medicine and Health and Professor in Neuroscience. Her mission for Graduate Studies is to 'advance curiosity-driven professionalism and research excellence for health-related global challenges, in a student-centred, respectful and inclusive environment.' With her team on the Graduate Studies committee, she is committed to supporting students to achieve and succeed in whatever area of education or research they are pursuing, including translation of learning into their work lives, and advancing their careers. https://www.ucc.ie/en/med-health/gradstudies/
Yvonne was Director of the BSc in Neuroscience in UCC from 2015-2020 in which she promoted collegiality, teamwork and engagement. Since her appointment in 2003, she has taught Anatomy and Neuroscience to students in Occupational, Speech and Language Therapy, Neuroscience, Medical, Dental, Pharmacy, Osteoarchaeology and Audiology programmes. In 2006 she was awarded a Postgraduate Certificate in Teaching and Learning in Higher Education (UCC), and in 2008 she received a National Academy award for the Integration of Research and Teaching and Learning. She was part of an interdisciplinary team that created ‘Brainpower’: a free online course and Digital Badge on brain and behaviour for student success. She provides both informal and formal mentoring to students and staff and was a role model on the Aurora leadership programme for women in Higher Education.
Yvonne contributes to the scientific and wider community through research projects with Down Syndrome Cork and industrial partners, and talks to schoolchildren, teachers, professional societies and the general public on adolescent and older adult brain health. She has organised conferences, symposia and public events including a symposium on the "Hippocampus in Health and Disease" in 2014 with guest speaker Nobel Laureate John O'Keefe, and “Brain Connections”, a public event on dementia and Parkinson’s in 2018. She is a judge for the Irish Laboratory Awards and sits on the Independent Advisory Board for the Wellcome/HRB Irish Clinical Academic Training (ICAT) programme and for Dementia Research Network Ireland (DNRI). She is a member of Society for Neuroscience, Psychoneuroimmunology Research Society, and Neuroscience Ireland.
The inter-related aims of Dr. Nolan’s research programme are:
1. To understand the mechanisms underpinning the interplay between chronic neuroinflammation and exercise on hippocampal neurogenesis (a form of brain plasticity involving the production of new neurons from stem cells) and behaviour (memory and mood) during sensitive periods of the lifespan, specifically adolescence and older age
2. To interrogate the role of the gut microbiota in Alzheimer’s disease and in exercise-induced changes in inflammation, brain plasticity and behaviour in ageing
3. To identify the inflammatory mechanisms underlying the negative effects of a cafeteria diet on brain and behaviour and to investigate exercise as a mitigating strategy
4. To increase understanding of learning strategies, academic motivation, well-being, and anxiety linked with inflammation in adolescent undergraduate students in UCC
5. To investigate musical training on cognition and sociability in children with Down Syndrome
Leadership in Anatomy: Dr. Nolan has developed curriculum, taught and assessed Anatomy to students in Occupational, Speech and Language Therapy, Medicine, Dentistry, Pharmacy, and to postgraduate students in Anatomy, Osteoarchaeology and Audiology since her appointment in 2003. She was Anatomy liaison for School of Clinical Therapies (2004–2016). She has represented the department at School and Exam Boards and in the accreditation and re-accreditation of both Occupational Therapy and Speech and Language Therapy programmes since 2006. She co-ordinates/previously co-ordinated six anatomy modules (AN1060; AN1061; AN1074; AN3005; AN3006; AN6001).
Research-led teaching: Dr. Nolan draws on her expertise in cognitive function, inflammation and lifestyle factors influencing the brain in her teaching. She leads an active research group in Neuroscience and impart her expertise in three research-based modules (AN4011, AN4013, AN4014) which she coordinates. She has supervised 6 taught MSc dissertation students, >50 undergraduate projects, >60 library projects and seven ERASMUS projects (Grenoble, Beijing, Amsterdam, Toulouse).
Teaching Qualification:
Chair of BSc Neuroscience curriculum committee (2016-present)
College of SEFS Academic Programmes and Curriculum Development Committee (2016 - 2020)
College of SEFS Board of Studies for Biological and Chemical Science degree (2016 - 2020)
School of Medicine Research and Postgraduate Affairs Committee, UCC (2012–present)
Continuing Professional Development Steering Group, College of Medicine & Health (2015-2018)
School of Medicine Curriculum Committee (2012–2014)
Departmental Representative on the Clinical Therapies School Board (2003-2017)
Chair of Departmental Anatomy Curriculum Committee (2012-2014)
Chair of Departmental Graduate Studies Committee (2008-2013)
Biography
Yvonne Nolan is a Professor in Anatomy and Neuroscience, Funded Investigator in APC Microbiome Ireland and a Science Foundation Ireland Investigator. She leads a research team investigating the impact of modifiable lifestyle factors such as exercise, stress and diet on memory and mood though the lifespan. Recent work focuses on adolescence, middle age an Alzheimer's. The role of the gut microbiome and hippocampal neurogenesis is of particular interest. Research in Professor Nolan’s team investigates Yvonne graduated from NUI, Galway with a BSc (Hons) in Biochemistry, and a PhD in Neuropharmacology. She was a visiting scholar at McGill University Montreal, Canada and held postdoctoral positions in Trinity College, Dublin. In 2003 she was appointed as Lecturer in the Department of Anatomy and Neuroscience, UCC, in 2011 she was promoted to Senior Lecturer and to Professor in 2020.
Research in Professor Nolan's laboratory focuses on the effects of inflammation, exercise, stress and diet on hippocampal plasticity and neurogenesis (the birth of new neurons) and on associated learning, memory and mood throughout the lifespan. To date she has supervised >30 PhD/MSc/postdoctoral researchers/to completion and has also supervised numerous visiting and undergraduate students. She was awarded UCC’s Research Supervisor of the Year Award, 2016. She has a number of collaborations with academic and industrial partners and her team have had recognition for research in the form of prizes, image exhibition and media coverage. She has published >80 full-length journal articles and >150 conference abstracts. Her H-index is 37 (Google Scholar) and her work has been cited >5500 times. She has secured ~€5.5M in research funding as Lead Investigator from Science Foundation Ireland, Marigot Ireland Ltd, Molecular Medicine Ireland, Irish Research Council, Weston Trust, and Vasogen Inc., Canada. She was consortium lead on a European Centres of Excellence in Neurodegeneration (COEN) project.
Yvonne is Vice Dean of Graduate Studies in the College of Medicine and Health and Professor in Neuroscience. Her mission for Graduate Studies is to 'advance curiosity-driven professionalism and research excellence for health-related global challenges, in a student-centred, respectful and inclusive environment.' With her team on the Graduate Studies committee, she is committed to supporting students to achieve and succeed in whatever area of education or research they are pursuing, including translation of learning into their work lives, and advancing their careers. https://www.ucc.ie/en/med-health/gradstudies/
Yvonne was Director of the BSc in Neuroscience in UCC from 2015-2020 in which she promoted collegiality, teamwork and engagement. Since her appointment in 2003, she has taught Anatomy and Neuroscience to students in Occupational, Speech and Language Therapy, Neuroscience, Medical, Dental, Pharmacy, Osteoarchaeology and Audiology programmes. In 2006 she was awarded a Postgraduate Certificate in Teaching and Learning in Higher Education (UCC), and in 2008 she received a National Academy award for the Integration of Research and Teaching and Learning. She was part of an interdisciplinary team that created ‘Brainpower’: a free online course and Digital Badge on brain and behaviour for student success. She provides both informal and formal mentoring to students and staff and was a role model on the Aurora leadership programme for women in Higher Education.
Yvonne contributes to the scientific and wider community through research projects with Down Syndrome Cork and industrial partners, and talks to schoolchildren, teachers, professional societies and the general public on adolescent and older adult brain health. She has organised conferences, symposia and public events including a symposium on the "Hippocampus in Health and Disease" in 2014 with guest speaker Nobel Laureate John O'Keefe, and “Brain Connections”, a public event on dementia and Parkinson’s in 2018. She is a judge for the Irish Laboratory Awards and sits on the Independent Advisory Board for the Wellcome/HRB Irish Clinical Academic Training (ICAT) programme and for Dementia Research Network Ireland (DNRI). She is a member of Society for Neuroscience, Psychoneuroimmunology Research Society, and Neuroscience Ireland.
Research Interests
Research in Dr. Nolan’s group is focused on understanding how lifestyle factors such as exercise, stress and diet throughout the life course impact upon neuronal functions and behaviour, with a focus on inflammation as a critical mediator. We work on the role of the gut microbiome and hippocampal neurogenesis (the birth of new neurons) in mediating these environmental influences on the brain and behaviour. Concurrently, an awareness of modifiable lifestyle factors (exercise, diet, music) for brain health is promoted.The inter-related aims of Dr. Nolan’s research programme are:
1. To understand the mechanisms underpinning the interplay between chronic neuroinflammation and exercise on hippocampal neurogenesis (a form of brain plasticity involving the production of new neurons from stem cells) and behaviour (memory and mood) during sensitive periods of the lifespan, specifically adolescence and older age
2. To interrogate the role of the gut microbiota in Alzheimer’s disease and in exercise-induced changes in inflammation, brain plasticity and behaviour in ageing
3. To identify the inflammatory mechanisms underlying the negative effects of a cafeteria diet on brain and behaviour and to investigate exercise as a mitigating strategy
4. To increase understanding of learning strategies, academic motivation, well-being, and anxiety linked with inflammation in adolescent undergraduate students in UCC
5. To investigate musical training on cognition and sociability in children with Down Syndrome
Research Grants
| Project | Funding Body | Start Date | End Date | Award | |
|---|---|---|---|---|---|
| Wellcome Trust - Biomedical Vacation Scholarship Niall Savage The role of MKP-1 in inflammation-regulated differentiation of embryonic stems cells | Foreign Research Institute | 15-JUN-09 | 07-AUG-09 | €1,440.00 | |
| An unrestricted gift to support research activities in the laboratory of Professor Yvonne Nolan | Foundation Funded Research | 01-FEB-22 | 31-JAN-23 | €75,000.00 | |
| HEA COVID Support Call 4 | HEACOVID19 | 01-APR-25 | 31-OCT-25 | €12,333.00 | |
| Mechanisms Underlying the Role of Gut-microbiota in Exercise-induced Changes In Cognitive Function In Middle-age | Foreign Research Institute | 01-JUN-21 | 31-MAY-24 | €295,837.00 | |
| Investigation of the benefits of exercise in Alzheimer’s disease: focus on the microbiota-gut-brain axis | Irish Research Council | 01-SEP-22 | 31-AUG-26 | €110,000.00 | |
| HEACOVID19 | 01-OCT-20 | 30-NOV-20 | €7,161.00 | ||
| Marigot - Examination of the Anti-inflammatory Potential of Aquamin | Industry | 21-JUL-08 | 28-FEB-09 | €6,200.00 | |
| HEACOVID19 | 01-DEC-20 | 30-JUN-21 | €12,838.00 | ||
| Inflammation and Anxiety in Young Adults: Mapping Associations and Intervention Opportunities | Irish Research Council | 01-OCT-19 | 30-SEP-23 | €96,000.00 | |
| Miscellaneous | 30-SEP-16 | 30-OCT-18 | €17,364.00 | ||
| The role of the IL-1 type 1 receptor in the life, death and differentiation of adult hippocampal neural precursor cells | Science Foundation Ireland | 01-JAN-08 | 31-DEC-12 | €175,000.00 | |
| The nuclear receptor TLX as a cell intrinsic regulator underlying inflammation and stress-induced changes in hippocampal neurogenesis: relevance to cognitive disorders | Science Foundation Ireland | 01-APR-13 | 31-DEC-17 | €1,082,494.00 | |
| Transcription factor regulation of dopaminergic neural stem cell fate in an inflammatory environment | Irish Research Council | 01-JAN-08 | 31-DEC-11 | €72,009.00 | |
| Investigation of the effects of VP025 in progressive rat models of Parkinson’s disease. | Vasogen Inc., Canada | 01-JAN-04 | 30-SEP-07 | €348,741.00 | |
| Examination of the cognitive enhancing potential of seaweed-derived mineral-rich nutraceuticals | Science Foundation Ireland | 01-JAN-14 | 31-DEC-16 | €120,379.00 | |
| Effect of pro-inflammatory cytokines on the fate of embryonic hippocampal neural precursor cells | Vasogen Inc., Canada | 21-JUL-08 | 28-MAR-09 | €48,000.00 | |
| Cognitive Enhancing Potential of Seaweed-derived Mineral Rich Nutraceticals | Industry | 01-OCT-16 | 31-MAR-17 | €38,667.00 | |
| HEACOVID19 | 01-SEP-21 | 30-APR-23 | €12,333.00 | ||
| Science Foundation of Ireland | 01-DEC-20 | 30-NOV-24 | €1,072,305.00 | ||
| Inflammatory Mechanisms | Irish Research Council | 01-SEP-19 | 30-APR-23 | €77,833.00 | |
| Centres of Excellence in Neurodegeneration (CoEN) 2017 call for proposals: Pathfinder III | Science Foundation of Ireland | 01-MAR-18 | 30-JUN-21 | €197,931.00 | |
| [Vasogen Irl Ltd] (Nolan Y/Sullivan A) V ( R11022) | Irish Research Council | 01-OCT-04 | 31-AUG-08 | €63,960.00 | |
| IRCSET PG "Inflammation, Wnt signalling & Neurogenesis" | Irish Research Council for Science, Engineering & Technology (IRCSET) | 01-JAN-08 | 31-DEC-11 | €72,009.00 | |
| Marigot - Examination of the Anti-inflammatory Potential of Aquamin | Industry | 21-JUL-08 | 28-FEB-09 | €6,200.00 | |
| Inflammatory Mechanisms | Irish Research Council | 01-SEP-19 | 30-APR-23 | €77,833.00 | |
| Harnessing the power of adolescent brain and behaviour for enhanced learning, wellbeing and student success: the interdisciplinary creation and piloting of an innovative online digital badge for higher education academic and academic support services staff | National Forum for the Enhancement of Teaching and Learning in Higher Education | €30,000.00 | |||
| Role of gut microbiota in lifestyle-induced changes in brain homeostasis and peripheral immune status. | Irish Research Council | 01-OCT-18 | 30-NOV-20 | €91,846.00 | |
| Centres of Excellence in Neurodegeneration (CoEN) 2017 call for proposals: Pathfinder III | Science Foundation of Ireland | 01-MAR-18 | 30-JUN-21 | €197,931.00 | |
| Neurological Effects of Musical Training in Children with Down Syndrome | Miscellaneous | 17-JAN-19 | 31-DEC-19 | €5,000.00 | |
| Diagnosis and monitoring of therapeutic response in glioma patients through sequencing of cerebrospinal fluid derived circulating tumour DNA, microRNA, and characterisation of plasma derived extracellular vesicles. | UCC TRAP (Translational Research Access Programme) | 01-SEP-18 | 30-SEP-19 | €9,950.00 | |
| Miscellaneous | 30-SEP-16 | 30-OCT-18 | €17,364.00 | ||
| The nuclear receptor TLX as a cell intrinsic regulator underlying inflammation and stress-induced changes in hippocampal neuropgenesis - relevance to cognitive disorders. | Science Foundation of Ireland | 01-APR-13 | 30-SEP-18 | €1,082,496.00 | |
| Transcriptomic analysis of inflammatory-induced changes in the hippocampus: role of nuclear receptor TLX | Science Foundation Ireland | 01-JAN-16 | 31-DEC-17 | €37,000.00 | |
| Healthy Brain Aging – Tús Maith Leath na hOibre” (A good start is half the work) | Federation of Neuroscience | 01-JAN-16 | €900.00 | ||
| Examination of the cognitive enhancing potential of seaweed-derived mineral-rich nuraceuticals. | Science Foundation of Ireland | 01-DEC-14 | 30-JUN-17 | €156,463.00 | |
| Examination of the cognitive enhancing potential of seaweed-derived mineral-rich nutraceuticals in aging | Marigot Ltd. | 01-OCT-16 | 31-MAR-17 | €38,667.00 | |
| Molecular Medicine Ireland: Nurr1 as a therapeutic target in Parkinson’s disease. | Other: Not Listed | 01-OCT-13 | 30-SEP-16 | €32,100.00 | |
| Neuropathological characterisation of human post-mortem MS lesions. | British Neuropathological Society | 24-NOV-14 | 27-NOV-15 | €6,300.00 | |
| Neuropathological analysis of MKPT1 in post mortem human Multiple Sclerosis tissue. | Health Research Board | 10-JUN-13 | 31-JUL-13 | €2,000.00 | |
| The role of MKP1 in the survival and functional integration of dopaminergic neurones | Other: Not Listed | 01-JAN-09 | 31-DEC-12 | €66,120.00 | |
| SFI "Role of IL-1 Type 1 Receptor in life,death & diferentiation of Adult Hippocampal Neural prec ce | Science Foundation of Ireland | 30-AUG-08 | 31-AUG-12 | €221,006.00 | |
| Transcription factor regulation of dopaminergic neural stem cell fate in an inflammatory environment. | Irish Research Council for Science, Engineering & Technology (IRCSET) | 01-OCT-10 | 30-JUN-12 | €72,000.00 | |
| SFI OIP 2010 Equipment Refurbishment | Science Foundation of Ireland | 01-JAN-10 | 31-DEC-11 | €9,602.00 | |
| Deciphering the role of Wnt signalling on inflammation-induced changes in hippocampal neurogenesis | Irish Research Council | 01-JAN-07 | 31-DEC-10 | €72,009.00 | |
| Wellcome Trust - Biomedical Vacation Scholarship Niall Savage The role of MKP-1 in inflammation-regulated differentiation of embryonic stems cells | Foreign Research Institute | 15-JUN-09 | 07-AUG-09 | €1,440.00 | |
| Effect of pro-inflammatory cytokines on the fate of embryonic hippocampal neural precursor cells | Vasogen Inc., Canada | 01-OCT-05 | 31-AUG-08 | €48,000.00 | |
| Examination of the anti-inflammatory potential of Aquamin | Marigot Ltd. | 01-JAN-08 | 31-DEC-08 | €9,950.00 | |
| The role of inflammation and p38 in 6-OHDA-induced dopamine neuronal death – implications for Parkinson’s disease | Irish Research Council | 01-OCT-04 | 31-AUG-08 | €63,960.00 | |
| [Vasogen Irl Ltd]{Nolan Y/Sullivan A} V | Industry | 01-JAN-04 | 30-SEP-07 | €348,741.00 |
Contract Researchers
| Researcher Name | Project | Role | Funding Body | |
|---|---|---|---|---|
| Dr Francisco Donoso | Mechanisms underlying the role of gut-microbiota in exercise-induced changes in cognitive function in middle-age | Postdoctoral Researcher | Other: Not Listed | |
| Dr Thieza Melo | Mechanisms underpinning the interplay between chronic neuroinflammation and exercise on cognitive function during middle age. | Research Assistant | Science Foundation Ireland | |
| Dr Sarah Nicolas | Mechanisms underpinning the interplay between chronic neuroinflammation and exercise on cognitive function during middle age. | Postdoctoral Researcher | Science Foundation Ireland | |
| Dr Stephen Shovlin | Mechanisms underpinning the interplay between chronic neuroinflammation and exercise on cognitive function during middle age. | Postdoctoral Researcher | Science Foundation Ireland | |
| Dr. Cara Heuston | The nuclear receptor TLX as a cell intrinsic regulator underlying inflammation and stress-induced changes in hippocampal neurogenesis: relevance to cognitive disorders | Postdoctoral Researcher | Science Foundation Ireland | |
| Dr. Sarah Nicolas | Role of gut microbiota in lifestyle-induced changes in brain homeostasis and peripheral immune status. | Postdoctoral Researcher | Irish Research Council | |
| Dr. Stefanie Grabrucker | Gut microbes, Neuroinflammation and Alzheimer's disease: determining the immunoregulatory role of gut microbiota on brain and behaviour | Postdoctoral Researcher | Science Foundation Ireland | |
| Dr Erin Dolan | Examination of the cognitive enhancing potential of seaweed-derived mineral rich nutraceuticals | Research Associate | Marigot Ltd. | |
| Dr. Alan Hoban | Transcriptomic analysis of inflammatory-induced changes in the hippocampus: role of nuclear receptor TLX | Postdoctoral Researcher | Science Foundation Ireland | |
| Dr. Caitriona Long-Smith | Examination of the cognitive enhancing potential of seaweed-derived mineral-rich nutraceuticals | Postdoctoral Researcher | Science Foundation Ireland | |
| Patrick Fitzgerald | Analysis of the anti-inflammatory/neuroprotective effects of VP025 in progressive models of Parkinsons disease | Research Associate | Vasogen Inc., Canada | |
| Dr Andrew Fisher | Analysis of the anti-inflammatory/neuroprotective effects of novel phospholipids-based drug formulation in a rat model of Parkinsons disease (co-supervised by Dr. Aideen Sullivan). | Postdoctoral Researcher | Vasogen Inc., Canada | |
| Sinead Ryan | Examination of the anti-inflammatory potential of Aquamin. | Research Associate | Marigot Ltd. | |
| Eleanor Tuohy | Analysis of the anti-inflammatory/neuroprotective effects of novel phospholipids-based drug formulation in a rat model of Parkinsons disease. | Research Associate | Vasogen Inc., Canada | |
| Suzanne Crotty | Analysis of the anti-inflammatory/neuroprotective effects of VP025 in progressive models of Parkinsons disease (co-supervised by Dr. Aideen Sullivan). | Research Associate | Vasogen Inc., Canada | |
| Dawn Harris | Analysis of the anti-inflammatory/neuroprotective effects of novel phospholipids-based drug formulation in a rat model of Parkinsons disease (co-supervised by Dr. Aideen Sullivan). | Research Associate | Vasogen Inc., Canada | |
| Sharon O'Brien | Analysis of the anti-inflammatory/neuroprotective effects of novel phospholipid-based drug formulation in a rat model of Parkinson's disease | Research Associate | Vasogen Inc., Canada | |
| Niall Savage | The role of MKP-1 in inflammation-regulated differentiation of embryonic stem cells | Research Associate | Wellcome Trust | |
| Richard Magee | Neuropathological analysis of MKPT1 in post mortem human Multiple Sclerosis tissue | Research Associate | Health Research Board | |
| Caroline Browne | Analysis of the anti-inflammatory/neuroprotective effects of novel phospholipid-based drug formulation in a rat model of Parkinson's disease | Research Associate | Vasogen Inc., Canada |
Publications
Conference Publications
| Year | Publication | |
|---|---|---|
| (2017) | Glial Cells in Health and Disease M Fitzpatrick, I Sweeney, N Boyle, R Magee, S-M Yap, T Hogan, Y Nolan, O Toole, W Hind, E Downer (2017) Assessing toll-like receptor signalling in Multiple Sclerosis both centrally and peripherally Glial Cells in Health and Disease [Details] | |
| (2017) | Neurogastroenterology and Motiltiy S O'Donovan, EK Crowley, J Browne, O O'Sullivan, OF O'Leary, S Timmons, YM Nolan, PW O'Toole, DJ Clarke, NP Hyland, SA Joyce, AM Sullivan, C O'Neill (2017) Investigation of the brain gut axis in the rAAV-alpha-synuclein PD model: Reveals enteric nervous system pathology and alterations in the gut microbiome Neurogastroenterology and Motiltiy , pp.33-34 [DOI] [Details] | |
| (2017) | European Neuropsychopharmacology B.R. Levone, Y.M. Nolan, J.F. Cryan, O.F. O’Leary (2017) Neural progenitor cells from the ventral hippocampus are more sensitive to long-term exposure to corticosterone European Neuropsychopharmacology [DOI] [Details] | |
| (2017) | European Brain and Behaviour Society (EBBS) O'Leary JD, Hoban AE, O'Leary OF, Cryan JF, Nolan YM (2017) DIFFERENTIAL EFFECTS OF EXERCISE DURING ADOLESCENCE AND ADULTHOOD ON COGNITION AND PLASTICITY European Brain and Behaviour Society (EBBS) [Details] | |
| (2017) | AD/PDTM 2017, the 13th International Conference on Alzheimer's and Parkinson's Diseases and Related Neurological Disorders O’Donovan SM, Crowley E, Browne J, O’Sullivan O, O’Leary OF, Timmons S, Nolan YM, O’Toole PW, Clarke DJ, Hyland NP, Joyce SA, Sullivan AM, O’Neill C (2017) The brain ↔gut axis in Parkinson’s disease: defining gut pathology and the impact of exercise in the rAAV-α-synuclein rat model of PD AD/PDTM 2017, the 13th International Conference on Alzheimer's and Parkinson's Diseases and Related Neurological Disorders , 29-MAR-17 - 02-APR-17 [Details] | |
| (2017) | NEUROGASTROENTEROLOGY AND MOTILITY S O'Donovan, EK Crowley, J Browne, O O'Sullivan, OF O'Leary, S Timmons, YM Nolan, PW O'Toole, DJ Clarke, NP Hyland, SA Joyce, AM Sullivan, C O'Neill (2017) Investigation of the brain gut axis in the rAAV-alpha-synuclein PD model: Reveals enteric nervous system pathology and alterations in the gut microbiome NEUROGASTROENTEROLOGY AND MOTILITY [Details] | |
| (2017) | ECNP workshop for Junior Scientists in Europe Levone BR, Nolan YM, Cryan JF, O'Leary OF (2017) Region-specific effects of corticosterone on neural progenitors along the dorso-ventral axis of the hippocampus ECNP workshop for Junior Scientists in Europe , 09-MAR-17 - 12-MAR-17 [Details] | |
| (2016) | European Neuropsychopharmacology D. Kozareva, C. Hueston, C. O'Léime, J. Cryan, Y. Nolan (2016) TLX, a regulator of neural stem cell self-renewal, is required for microglial integrity in the adult mouse dentate gyrus European Neuropsychopharmacology [DOI] [Details] | |
| (2016) | Brain, Behavior, and Immunity C.M.Hueston, C.S.Ó’Léime, D.A.Kozareva, J.F.Cryan, Y.M.Nolan (2016) Lentiviral overexpression of interleukin-1β in the hippocampus induces neurogenesis-associated cognitive deficits in adult male Sprague–Dawley rats Brain, Behavior, and Immunity [Details] | |
| (2016) | European Neuropsychopharmacology C.M. Hueston, C.S. O'Léime, D.A. Kozareva, J.F. Cryan, Y.M. Nolan (2016) Hippocampal overexpression of interleukin-1ß induces neurogenesis-associated cognitive deficits in adult male rats European Neuropsychopharmacology [Details] | |
| (2016) | Brain, Behavior, and Immunity C.S.OLeime, J.F.Cryan, Y.M.Nolan (2016) IL-1β negatively impacts upon expression of both inflammatory and neurogenesis-associated signalling molecules in hippocampal neural stem cells in vitro Brain, Behavior, and Immunity [Details] |
Peer Reviewed Journals
| Year | Publication | |
|---|---|---|
| (2020) | 'Depression's Unholy Trinity: Dysregulated Stress, Immunity, and the Microbiome' Cruz-Pereira JS;Rea K;Nolan YM;O'Leary OF;Dinan TG;Cryan JF; (2020) 'Depression's Unholy Trinity: Dysregulated Stress, Immunity, and the Microbiome'. Annual Review Of Psychology, 71 [DOI] [Details] | |
| (2019) | 'Chronic intrahippocampal interleukin-1ß overexpression in adolescence impairs hippocampal neurogenesis but not neurogenesis-associated cognition' Pawley, Lauren C.; Hueston, Cara M.; O'Leary, James D.; Kozareva, Danka A.; Cryan, John F.; O'Leary, Olivia F.; Nolan, Yvonne M. (2019) 'Chronic intrahippocampal interleukin-1ß overexpression in adolescence impairs hippocampal neurogenesis but not neurogenesis-associated cognition'. Brain Behav Immun, [DOI] [Full Text] [Details] | |
| (2019) | 'Nigral overexpression of a-synuclein in a rat Parkinson’s disease model indicates alterations in the enteric nervous system and the gut microbiome' O’Donovan S.;Crowley E.;Brown J.;O’Sullivan O.;O’Leary O.;Timmons S.;Nolan Y.;Clarke D.;Hyland N.;Joyce S.;Sullivan A.;O'Neill C. (2019) 'Nigral overexpression of a-synuclein in a rat Parkinson’s disease model indicates alterations in the enteric nervous system and the gut microbiome'. Neurogastroenterology and Motility, [DOI] [Details] | |
| (2019) | 'Lutein and zeaxanthin: The possible contribution, mechanisms of action and implications of modern dietary intake for cognitive development in children' Loskutova E, Shah K, Flitcroft ID, Setti A, Butler JS, Nolan Y, Paudel N, Loughman J. (2019) 'Lutein and zeaxanthin: The possible contribution, mechanisms of action and implications of modern dietary intake for cognitive development in children'. Neuronal Signaling, 3 (1) [DOI] [Details] | |
| (2019) | 'Born this way: Hippocampal neurogenesis across the lifespan' Kozareva, DA;Cryan, JF;Nolan, YM (2019) 'Born this way: Hippocampal neurogenesis across the lifespan'. Aging Cell, [DOI] [Details] | |
| (2019) | 'Toxoplasma gondii: An unwelcome visitor that damages social and neuronal connections' Nolan YM; (2019) 'Toxoplasma gondii: An unwelcome visitor that damages social and neuronal connections'. Brain Behav Immun, 80 [DOI] [Details] | |
| (2019) | 'A role for the orphan nuclear receptor TLX in the interaction between neural precursor cells and microglia' Kozareva DA, Moloney GM, Hoban EA, Rossini V, Nally K, Cryan JF, Nolan YM. (2019) 'A role for the orphan nuclear receptor TLX in the interaction between neural precursor cells and microglia'. Neuronal Signaling, 3 (1) [DOI] [Details] | |
| (2019) | 'Differential effects of adolescent and adult-initiated exercise on cognition and hippocampal neurogenesis' O'Leary, James D.; Hoban, Alan E.; Murphy, Ashley; O'Leary, Olivia F.; Cryan, John F.; Nolan, Yvonne M. (2019) 'Differential effects of adolescent and adult-initiated exercise on cognition and hippocampal neurogenesis'. Hippocampus, 29 :352-365 [DOI] [Full Text] [Details] | |
| (2019) | 'Exercise as a therapeutic intervention for motor and non-motor symptoms in Parkinson's disease: Evidence from rodent models' Crowley EK;Nolan YM;Sullivan AM; (2019) 'Exercise as a therapeutic intervention for motor and non-motor symptoms in Parkinson's disease: Evidence from rodent models'. Progress In Neurobiology, 172 [DOI] [Details] | |
| (2019) | 'TLX knockdown in the dorsal dentate gyrus of juvenile rats differentially affects adolescent and adult behaviour' Kozareva, DA;Foley, T;Moloney, GM;Cryan, JF;Nolan, YM (2019) 'TLX knockdown in the dorsal dentate gyrus of juvenile rats differentially affects adolescent and adult behaviour'. Behavioural Brain Research, 360 :36-50 [DOI] [Details] | |
| (2019) | 'Absence of the neurogenesis-dependent nuclear receptor TLX induces inflammation in the hippocampus' Kozareva, DA;Hueston, CM;O'Leime, CS;Crotty, S;Dockery, P;Cryan, JF;Nolan, YM (2019) 'Absence of the neurogenesis-dependent nuclear receptor TLX induces inflammation in the hippocampus'. Journal of Neuroimmunology, 331 :87-96 [DOI] [Details] | |
| (2019) | 'Differential effects of adolescent and adult-initiated voluntary exercise on context and cued fear conditioning' O'Leary JD;Hoban AE;Cryan JF;O'Leary OF;Nolan YM; (2019) 'Differential effects of adolescent and adult-initiated voluntary exercise on context and cued fear conditioning'. Neuropharmacology, 45 (Pt A):49-58 [DOI] [Details] | |
| (2018) | 'Chronic interleukin-1 beta in the dorsal hippocampus impairs behavioural pattern separation' Hueston, CM;O'Leary, JD;Hoban, AE;Kozareva, DA;Pawley, LC;O'Leary, OF;Cryan, JF;Nolan, YM (2018) 'Chronic interleukin-1 beta in the dorsal hippocampus impairs behavioural pattern separation'. Brain Behav Immun, 74 :252-264 [DOI] [Details] | |
| (2018) | 'Exercise as therapy for Parkinson's?' Crowley EK;Nolan YM;Sullivan AM; (2018) 'Exercise as therapy for Parkinson's?'. Aging, 10 (7) [DOI] [Details] | |
| (2018) | 'Dietary Supplementation with a Magnesium-Rich Marine Mineral Blend Enhances the Diversity of Gastrointestinal Microbiota' Crowley, EK;Long-Smith, CM;Murphy, A;Patterson, E;Murphy, K;O'Gorman, DM;Stanton, C;Nolan, YM (2018) 'Dietary Supplementation with a Magnesium-Rich Marine Mineral Blend Enhances the Diversity of Gastrointestinal Microbiota'. Marine Drugs, 16 [DOI] [Details] | |
| (2018) | 'A low-cost touchscreen operant chamber using a Raspberry Pi' O'Leary, JD;O'Leary, OF;Cryan, JF;Nolan, YM (2018) 'A low-cost touchscreen operant chamber using a Raspberry Pi'. Behavior research methods, 50 :2523-2530 [DOI] [Details] | |
| (2018) | 'The orphan nuclear receptor TLX regulates hippocampal transcriptome changes induced by IL-1ß' Ó Léime, Ciarán S.; Hoban, Alan E.; Hueston, Cara M.; Stilling, Roman; Moloney, Gerard; Cryan, John F.; Nolan, Yvonne M. (2018) 'The orphan nuclear receptor TLX regulates hippocampal transcriptome changes induced by IL-1ß'. Brain, Behavior, and Immunity, [DOI] [Full Text] [Details] | |
| (2018) | 'Neuroprotective effects of voluntary running on cognitive dysfunction in an alpha-synuclein rat model of Parkinson's disease' Crowley, EK;Nolan, YM;Sullivan, AM (2018) 'Neuroprotective effects of voluntary running on cognitive dysfunction in an alpha-synuclein rat model of Parkinson's disease'. Neurobiology of Aging, 65 :60-68 [DOI] [Details] | |
| (2018) | 'Treatment with the noradrenaline re-uptake inhibitor atomoxetine alone and in combination with the alpha 2-adrenoceptor antagonist idazoxan attenuates loss of dopamine and associated motor deficits in the LPS inflammatory rat model of Parkinson's disease' Yssel, JD;O'Neill, E;Nolan, YM;Connor, TJ;Harkin, A (2018) 'Treatment with the noradrenaline re-uptake inhibitor atomoxetine alone and in combination with the alpha 2-adrenoceptor antagonist idazoxan attenuates loss of dopamine and associated motor deficits in the LPS inflammatory rat model of Parkinson's disease'. Brain Behav Immun, 69 :456-469 [DOI] [Details] | |
| (2018) | 'Deletion of Tlx and social isolation impairs exercise-induced neurogenesis in the adolescent hippocampus' Kozareva DA, O'Leary OF, Cryan JF, Nolan YM. (2018) 'Deletion of Tlx and social isolation impairs exercise-induced neurogenesis in the adolescent hippocampus'. Hippocampus, 28 (1):3-11 [Details] | |
| (2018) | 'TLX is an intrinsic regulator of the negative effects of IL-1 beta on proliferating hippocampal neural progenitor cells' O'Leime, CS;Kozareva, DA;Hoban, AE;Long-Smith, CM;Cryan, JF;Nolan, YM (2018) 'TLX is an intrinsic regulator of the negative effects of IL-1 beta on proliferating hippocampal neural progenitor cells'. The Faseb Journal, 32 :613-624 [DOI] [Details] | |
| (2018) | 'Regulation of behaviour by the nuclear receptor TLX' O'Leary JD;O'Leary OF;Cryan JF;Nolan YM; (2018) 'Regulation of behaviour by the nuclear receptor TLX'. Genes Brain And Behavior, 17 (3) [DOI] [Details] | |
| (2017) | 'ADOLESCENT SOCIAL ISOLATION STRESS UNMASKS THE COMBINED EFFECTS OF ADOLESCENT EXERCISE AND ADULT INFLAMMATION ON HIPPOCAMPAL NEUROGENESIS AND BEHAVIOR' Hueston, CM;Cryan, JF;Nolan, YM (2017) 'ADOLESCENT SOCIAL ISOLATION STRESS UNMASKS THE COMBINED EFFECTS OF ADOLESCENT EXERCISE AND ADULT INFLAMMATION ON HIPPOCAMPAL NEUROGENESIS AND BEHAVIOR'. Neuroscience, 365 :226-236 [DOI] [Details] | |
| (2017) | 'Nuclear deterrents: Intrinsic regulators of IL-1ß-induced effects on hippocampal neurogenesis' O'Léime CS;Cryan JF;Nolan YM; (2017) 'Nuclear deterrents: Intrinsic regulators of IL-1ß-induced effects on hippocampal neurogenesis'. Brain Behav Immun, 66 [DOI] [Details] | |
| (2017) | 'Stress and adolescent hippocampal neurogenesis: diet and exercise as cognitive modulators' Hueston, Cara M.; Cryan, John F.; Nolan, Yvonne M. (2017) 'Stress and adolescent hippocampal neurogenesis: diet and exercise as cognitive modulators'. Translational psychiatry, 7 [DOI] [Full Text] [Details] | |
| (2017) | 'Deletion of Tlx and social isolation impairs exercise-induced neurogenesis in the adolescent hippocampus' Kozareva, Danka A.,O'Leary, Olivia F.,Cryan, John F.,Nolan, Yvonne M. (2017) 'Deletion of Tlx and social isolation impairs exercise-induced neurogenesis in the adolescent hippocampus'. Hippocampus, [DOI] [Full Text] [Details] | |
| (2016) | 'The nuclear receptor Tlx regulates motor, cognitive and anxiety-related behaviours during adolescence and adulthood' O'Leary JD;Kozareva DA;Hueston CM;O'Leary OF;Cryan JF;Nolan YM; (2016) 'The nuclear receptor Tlx regulates motor, cognitive and anxiety-related behaviours during adolescence and adulthood'. Behavioural Brain Research, 306 [DOI] [Details] | |
| (2016) | 'Neuroinflammation negatively affects adult hippocampal neurogenesis and cognition: can exercise compensate?' Ryan, SM;Nolan, YM (2016) 'Neuroinflammation negatively affects adult hippocampal neurogenesis and cognition: can exercise compensate?'. Neuroscience and Biobehavioral Reviews, 61 :121-131 [DOI] [Details] | |
| (2015) | 'Glycogen synthase kinase-3 as a therapeutic target for cognitive dysfunction in neuropsychiatric disorders' O'Leary O;Nolan Y; (2015) 'Glycogen synthase kinase-3 as a therapeutic target for cognitive dysfunction in neuropsychiatric disorders'. Cns Drugs, 29 (1) [DOI] [Details] | |
| (2015) | 'Mitogen-Activated Protein Kinase Phosphatase (MKP)-1 in Nervous System Development and Disease' Collins L.M., Downer E.J., Toulouse A., Nolan Y.M. (2015) 'Mitogen-Activated Protein Kinase Phosphatase (MKP)-1 in Nervous System Development and Disease'. Molecular Neurobiology, 51 (June):1158-1167 [DOI] [Details] | |
| (2015) | 'Knockdown of interleukin-1 receptor 1 is not neuroprotective in the 6-hydroxydopamine striatal lesion rat model of Parkinson's disease' Walsh, S,Gavin, A,Wyatt, S,O'Connor, C,Keeshan, K,Nolan, YM,O'Keeffe, GW,Sullivan, AM (2015) 'Knockdown of interleukin-1 receptor 1 is not neuroprotective in the 6-hydroxydopamine striatal lesion rat model of Parkinson's disease'. The International journal of neuroscience, 125 :70-77 [DOI] [Details] | |
| (2015) | 'The Omega-3 Polyunsaturated Fatty Acid Docosahexaenoic Acid (DHA) Reverses Corticosterone-Induced Changes in Cortical Neurons' Pusceddu, Matteo M.; Nolan, Yvonne M.; Green, Holly F.; Robertson, Ruairi C.; Stanton, Catherine; Kelly, Philip; Cryan, John F.; Dinan, Timothy G. (2015) 'The Omega-3 Polyunsaturated Fatty Acid Docosahexaenoic Acid (DHA) Reverses Corticosterone-Induced Changes in Cortical Neurons'. International Journal of Neuropsychopharmacology, 9 (6) [DOI] [Full Text] [Details] | |
| (2015) | 'A Role for mitogen-activated protein kinase phosphatase 1(MKP1) in neural cell development and survival' Toulouse A., Nolan Y.M. (2015) 'A Role for mitogen-activated protein kinase phosphatase 1(MKP1) in neural cell development and survival'. Neural Regeneration Research, 10 (11):1748-1749 [DOI] [Details] | |
| (2014) | 'Inflammation and the developing brain: consequences for hippocampal neurogenesis and behavior' Green HF, Nolan YM (2014) 'Inflammation and the developing brain: consequences for hippocampal neurogenesis and behavior'. Neuroscience and biobehavioral reviews, 40 :20-34 [DOI] [Details] | |
| (2013) | 'Imaging of neurosphere oxygenation with phosphorescent probes' Dmitriev, RI,Zhdanov, AV,Nolan, YM,Papkovsky, DB (2013) 'Imaging of neurosphere oxygenation with phosphorescent probes'. Biomaterials, 34 :9307-9317 [DOI] [Details] | |
| (2013) | 'Mitogen-Activated Protein Kinase Phosphatase (MKP)-1 as a Neuroprotective Agent: Promotion of the Morphological Development of Midbrain Dopaminergic Neurons' Collins, LM;O'Keeffe, GW;Long-Smith, CM;Wyatt, SL;Sullivan, AM;Toulouse, A;Nolan, YM (2013) 'Mitogen-Activated Protein Kinase Phosphatase (MKP)-1 as a Neuroprotective Agent: Promotion of the Morphological Development of Midbrain Dopaminergic Neurons'. Neuromolecular medicine, 15 :435-446 [DOI] [Details] | |
| (2013) | 'Parkinson's Disease in the Nuclear Age of Neuroinflammation' Nolan Y.M., Sullivan A.M., Toulouse A. (2013) 'Parkinson's Disease in the Nuclear Age of Neuroinflammation'. Trends In Molecular Medicine, 19 :187-196 [DOI] [Details] | |
| (2013) | 'Negative regulation of TLX by IL-1 beta correlates with an inhibition of adult hippocampal neural precursor cell proliferation' Ryan, SM,O'Keeffe, GW,O'Connor, C,Keeshan, K,Nolan, YM (2013) 'Negative regulation of TLX by IL-1 beta correlates with an inhibition of adult hippocampal neural precursor cell proliferation'. Brain Behav Immun, 33 :7-13 [DOI] [Details] | |
| (2012) | 'A Phosphorescent Nanoparticle-Based Probe for Sensing and Imaging of (Intra)Cellular Oxygen in Multiple Detection Modalities' Kondrashina, AV,Dmitriev, RI,Borisov, SM,Klimant, I,O'Brien, I,Nolan, YM,Zhdanov, AV,Papkovsky, DB (2012) 'A Phosphorescent Nanoparticle-Based Probe for Sensing and Imaging of (Intra)Cellular Oxygen in Multiple Detection Modalities'. Advanced Functional Materials, 22 :4931-4939 [DOI] [Details] | |
| (2012) | 'GSK-3 mediates the release of IL-1 beta, TNF-alpha and IL-10 from cortical glia' Green, HF,Nolan, YM (2012) 'GSK-3 mediates the release of IL-1 beta, TNF-alpha and IL-10 from cortical glia'. Neurochemistry International, 61 :666-671 [DOI] [Details] | |
| (2012) | 'Contributions of central and systemic inflammation to the pathophysiology of Parkinson's disease' Collins L.M., Toulouse A., Connor T.J., Nolan Y.M. (2012) 'Contributions of central and systemic inflammation to the pathophysiology of Parkinson's disease'. Neuropharmacology, 62 (7):2154-2168 [DOI] [Full Text] [Details] | |
| (2012) | 'A role for interleukin-1 beta in determining the lineage fate of embryonic rat hippocampal neural precursor cells' Green, H.F., Treacy, E., Keohane, A.K., Sullivan, A.M., O’Keeffe, G.W., Nolan, Y.M. (2012) 'A role for interleukin-1 beta in determining the lineage fate of embryonic rat hippocampal neural precursor cells'. Molecular and cellular neurosciences, [Details] | |
| (2012) | 'Exposure of foetal neural progenitor cells to IL-1β impairs their proliferation and alters their differentiation - a role for maternal inflammation?' Crampton S.J., Collins L.M., Toulouse A., Nolan Y.M., O'Keeffe G.W. (2012) 'Exposure of foetal neural progenitor cells to IL-1β impairs their proliferation and alters their differentiation - a role for maternal inflammation?'. Journal of Neurochemistry, 120 (6):964-973 [DOI] [Details] | |
| (2012) | 'A Phosphorescent Nanoparticle-Based Probe for Sensing and Imaging of (Intra)Cellular Oxygen in Multiple Detection Modalities' Kondrashina AV, Dmitriev RI, Borisov SM, Klimant I, O'Brien I, Nolan YM, Zhdanov AV, Papkovsky DB (2012) 'A Phosphorescent Nanoparticle-Based Probe for Sensing and Imaging of (Intra)Cellular Oxygen in Multiple Detection Modalities'. Advanced Functional Materials, 22 (23):4931-4939 [Details] | |
| (2012) | 'A role for interleukin-1 beta in determining the lineage fate of embryonic rat hippocampal neural precursor cells' Green, HF;Treacy, E;Keohane, AK;Sullivan, AM;O'Keeffe, GW;Nolan, YM (2012) 'A role for interleukin-1 beta in determining the lineage fate of embryonic rat hippocampal neural precursor cells'. Molecular and Cellular Neuroscience, 49 :311-321 [DOI] [Details] | |
| (2011) | 'IL-1β inhibits axonal growth of developing sympathetic neurons' Nolan AM, Nolan YM, O'Keeffe GW; (2011) 'IL-1β inhibits axonal growth of developing sympathetic neurons'. Molecular and Cellular Neuroscience, 48 (2):142-150 [Details] | |
| (2011) | 'Evidence that the Marine-derived Multi-mineral Aquamin has Anti-inflammatory Effects on Cortical Glial-enriched Cultures' Ryan, S,O'Gorman, DM,Nolan, YM; (2011) 'Evidence that the Marine-derived Multi-mineral Aquamin has Anti-inflammatory Effects on Cortical Glial-enriched Cultures'. Phytotherapy Research, 25 :765-767 [DOI] [Details] | |
| (2010) | 'Interleukin-1beta released from lipopolysaccharide-stimulated rat glia contributes to the exacerbation of dopaminergic neuronal death induced by 6-hydroxydopamine' Long-Smith C.M., Collins L.M., Toulouse A., Sullivan A.M., Nolan Y.M. (2010) 'Interleukin-1beta released from lipopolysaccharide-stimulated rat glia contributes to the exacerbation of dopaminergic neuronal death induced by 6-hydroxydopamine'. Journal of Neuroimmunology, 226 :20-26 [DOI] [Details] | |
| (2010) | 'Interleukin-1β contributes to dopaminergic neuronal death induced by lipopolysaccharide-stimulated rat glia in vitro' Long-Smith C., Collins L., Toulouse A., Sullivan A.M., Nolan Y.M.; (2010) 'Interleukin-1β contributes to dopaminergic neuronal death induced by lipopolysaccharide-stimulated rat glia in vitro'. Journal of Neuroimmunology, 226 :20-26 [Details] | |
| (2010) | 'Tumour necrosis factor-alpha impairs neuronal differentiation but not proliferation of hippocampal neural precursor cells: Role of Hes1' Keohane, A., Ryan, S., Maloney, E., Sullivan, A.M., Nolan Y.M. (2010) 'Tumour necrosis factor-alpha impairs neuronal differentiation but not proliferation of hippocampal neural precursor cells: Role of Hes1'. Molecular and cellular neurosciences, 43 (1):127-135 [DOI] [Details] | |
| (2009) | 'The influence of microglia on the pathogenesis of Parkinson's disease' Long-Smith CM;Sullivan AM;Nolan YM; (2009) 'The influence of microglia on the pathogenesis of Parkinson's disease'. Progress In Neurobiology, 89 ((3)):277-287 [DOI] [Details] | |
| (2008) | 'Treatment with phosphotidylglycerol-based nanoparticles prevents motor deficits induced by proteasome inhibition: Implications for Parkinson's disease' Fitzgerald, P;Mandel, A;Bolton, AE;Sullivan, AM;Nolan, Y (2008) 'Treatment with phosphotidylglycerol-based nanoparticles prevents motor deficits induced by proteasome inhibition: Implications for Parkinson's disease'. Behavioural Brain Research, 195 :271-274 [DOI] [Details] | |
| (2008) | 'Neuroprotective effects of novel phosphatidylglycerol-based phospholipids in the 6-hydroxydopamine model of Parkinson's disease' Crotty, S., Fitzgerald, P., Tuohy, E., Harris, D.M., Fisher, A., Mandel, A., Bolton, A. E., Sullivan, A.M., Nolan, Y.M. (2008) 'Neuroprotective effects of novel phosphatidylglycerol-based phospholipids in the 6-hydroxydopamine model of Parkinson's disease'. The European Journal of Neuroscience, 27 (2):294-300 [DOI] [Details] | |
| (2007) | 'CD200 ligand-receptor interaction modulates microglial activation in vivo and in vitro: A role for IL-4' Lyons, A;Downer, EJ;Crotty, S;Nolan, YM;Mills, KHG;Lynch, MA (2007) 'CD200 ligand-receptor interaction modulates microglial activation in vivo and in vitro: A role for IL-4'. Neuroscience, 27 :8309-8313 [DOI] [Details] | |
| (2007) | 'CD200 ligand-receptor interaction modulates microglial activation in vivo and in vitro: A role for IL-4' Lyons, A,Downer, EJ,Crotty, S,Nolan, YM,Mills, KHG,Lynch, MA; (2007) 'CD200 ligand-receptor interaction modulates microglial activation in vivo and in vitro: A role for IL-4'. The Journal of Neuroscience, 27 :8309-8313 [DOI] [Details] | |
| (2007) | 'Treatment with dexamethasone and vitamin D3 attenuates neuroinflammatory age-related changes in rat hippocampus' Moore M, Piazza A, Nolan Y, Lynch MA; (2007) 'Treatment with dexamethasone and vitamin D3 attenuates neuroinflammatory age-related changes in rat hippocampus'. Synapse (New York, N.Y.), 61 (10):851-861 [DOI] [Details] | |
| (2006) | 'The age-related attenuation in long-term potentiation is associated with microglial activation' Griffin R, Nally R, Nolan Y, McCartney Y, Linden J, Lynch MA; (2006) 'The age-related attenuation in long-term potentiation is associated with microglial activation'. Journal of Neurochemistry, 99 (4):1263-1272 [DOI] [Details] | |
| (2005) | 'Role of interleukin-4 in regulation of age-related inflammatory changes in the hippocampus' Nolan Y, Maher FO, Martin DS, Clarke RM, Brady MT, Bolton AE, Mills KH, Lynch MA; (2005) 'Role of interleukin-4 in regulation of age-related inflammatory changes in the hippocampus'. The Journal of Biological Chemistry, 280 (10):9354-9362 [DOI] [Details] | |
| (2005) | 'Activation of c-Jun-N-terminal kinase is critical in mediating lipopolysaccharide-induced changes in the rat hippocampus' Barry CE, Nolan Y, Clarke RM, Lynch A, Lynch MA; (2005) 'Activation of c-Jun-N-terminal kinase is critical in mediating lipopolysaccharide-induced changes in the rat hippocampus'. Journal of Neurochemistry, 93 (1):221-231 [DOI] [Details] | |
| (2005) | 'Evidence of an anti-inflammatory role for Vasogen's immune modulation therapy' Nolan Y, Campbell VA, Bolton AE, Lynch MA; (2005) 'Evidence of an anti-inflammatory role for Vasogen's immune modulation therapy'. Neuroimmunomodulation, 12 (2):113-116 [DOI] [Details] | |
| (2005) | 'Downregulation of IL-4-induced signalling in hippocampus contributes to deficits in LTP in the aged rat' Maher FO, Nolan Y, Lynch MA; (2005) 'Downregulation of IL-4-induced signalling in hippocampus contributes to deficits in LTP in the aged rat'. Neurobiology of Aging, 26 (5):717-728 [DOI] [Details] | |
| (2004) | 'Evidence of a protective effect of phosphatidylserine-containing liposomes on lipopolysaccharide-induced impairment of long-term potentiation in the rat hippocampus' Nolan Y, Martin D, Campbell VA, Lynch MA; (2004) 'Evidence of a protective effect of phosphatidylserine-containing liposomes on lipopolysaccharide-induced impairment of long-term potentiation in the rat hippocampus'. Journal of Neuroimmunology, 151 (1-2):12-23 [DOI] [Details] | |
| (2004) | 'Lipopolysaccharide-induced increase in signalling in hippocampus is abrogated by IL-10--a role for IL-1 beta?' Lynch AM, Walsh C, Delaney A, Nolan Y, Campbell VA, Lynch MA; (2004) 'Lipopolysaccharide-induced increase in signalling in hippocampus is abrogated by IL-10--a role for IL-1 beta?'. Journal of Neurochemistry, 88 (3):635-646 [Details] | |
| (2003) | 'Evidence that lipopolysaccharide-induced cell death is mediated by accumulation of reactive oxygen species and activation of p38 in rat cortex and hippocampus' Nolan Y, Vereker E, Lynch AM, Lynch MA; (2003) 'Evidence that lipopolysaccharide-induced cell death is mediated by accumulation of reactive oxygen species and activation of p38 in rat cortex and hippocampus'. Experimental Neurology, 184 (2):794-804 [DOI] [Details] | |
| (2003) | 'Activation of p38 plays a pivotal role in the inhibitory effect of lipopolysaccharide and interleukin-1 beta on long term potentiation in rat dentate gyrus' Kelly A, Vereker E, Nolan Y, Brady M, Barry C, Loscher CE, Mills KH, Lynch MA; (2003) 'Activation of p38 plays a pivotal role in the inhibitory effect of lipopolysaccharide and interleukin-1 beta on long term potentiation in rat dentate gyrus'. The Journal of Biological Chemistry, 278 (21):19453-19462 [DOI] [Details] | |
| (2002) | 'Inhibition of constitutive nitric oxide production increases the severity of lipopolysaccharide-induced sickness behaviour: a role for TNF-alpha' Connor TJ, O'Sullivan J, Nolan Y, Kelly JP; (2002) 'Inhibition of constitutive nitric oxide production increases the severity of lipopolysaccharide-induced sickness behaviour: a role for TNF-alpha'. Neuroimmunomodulation, 10 (6):367-378 [DOI] [Details] | |
| (2002) | 'Attenuation of LPS-induced changes in synaptic activity in rat hippocampus by Vasogen's Immune Modulation Therapy' Nolan Y, Minogue A, Vereker E, Bolton AE, Campbell VA, Lynch MA; (2002) 'Attenuation of LPS-induced changes in synaptic activity in rat hippocampus by Vasogen's Immune Modulation Therapy'. Neuroimmunomodulation, 10 (1):40-46 [Details] | |
| (2001) | 'Evidence that interleukin-1beta and reactive oxygen species production play a pivotal role in stress-induced impairment of LTP in the rat dentate gyrus' Vereker E, O'Donnell E, Lynch A, Kelly A, Nolan Y, Lynch MA; (2001) 'Evidence that interleukin-1beta and reactive oxygen species production play a pivotal role in stress-induced impairment of LTP in the rat dentate gyrus'. The European Journal of Neuroscience, 14 (11):1809-1819 [Details] | |
| (2001) | 'The anti-inflammatory cytokine, interleukin (IL)-10, blocks the inhibitory effect of IL-1 beta on long term potentiation. A role for JNK' Kelly A, Lynch A, Vereker E, Nolan Y, Queenan P, Whittaker E, O'Neill LA, Lynch MA; (2001) 'The anti-inflammatory cytokine, interleukin (IL)-10, blocks the inhibitory effect of IL-1 beta on long term potentiation. A role for JNK'. The Journal of Biological Chemistry, 276 (49):45564-45572 [DOI] [Details] | |
| (2000) | 'Lipopolysaccharide administration produces time-dependent and region-specific alterations in tryptophan and tyrosine hydroxylase activities in rat brain' Nolan Y, Connor TJ, Kelly JP, Leonard BE; (2000) 'Lipopolysaccharide administration produces time-dependent and region-specific alterations in tryptophan and tyrosine hydroxylase activities in rat brain'. Journal of Neural Transmission, 107 (12):1393-1401 [Details] | |
| (1999) | 'Differential effect of chronic antidepressant treatments on lipopolysaccharide-induced depressive-like behavioural symptoms in the rat' Shen Y, Connor TJ, Nolan Y, Kelly JP, Leonard BE; (1999) 'Differential effect of chronic antidepressant treatments on lipopolysaccharide-induced depressive-like behavioural symptoms in the rat'. Life Sciences, 65 (17):1773-1786 [Details] |
Book Chapters
| Year | Publication | |
|---|---|---|
| (2014) | 'WILLIAM A 15-year-old sport-crazy Millennial in Ireland' Chambers, F;Murphy, N;Nolan, Y;Murphy, O (2014) 'WILLIAM A 15-year-old sport-crazy Millennial in Ireland' In: PEDAGOGICAL CASES IN PHYSICAL EDUCATION AND YOUTH SPORT. LONDON: ROUTLEDGE. [Details] | |
| (2011) | 'Analysis of the Impact of CD200 on Neurodegenerative Diseases' Miller, AM;Deighan, BF;Downer, E;Lyons, A;Henrich-Noack, P;Nolan, Y;Lynch, MA (2011) 'Analysis of the Impact of CD200 on Neurodegenerative Diseases' In: NEURODEGENERATIVE DISEASES - PROCESSES, PREVENTION, PROTECTION AND MONITORING. RIJEKA: INTECH EUROPE. [Details] | |
| (2012) | 'Inflammation in Parkinson's disease: causes and consequences' Collins L.M., Toulouse A., Nolan Y.M. (2012) 'Inflammation in Parkinson's disease: causes and consequences' In: Mechanisms in Parkinson's Disease - Models and Treatments. Croatia: InTech. [Full Text] [Details] |
Abstract
| Year | Publication | |
|---|---|---|
| (2015) | Docosahexaenoic acid as a novel strategy for stress-related disorders: reversal of corticosterone-induced changes in cortical neurons. Pusceddu, M,Nolan, YM,Green, HF,Kelly, P,Dinan, TG,Cryan, JF (2015) Docosahexaenoic acid as a novel strategy for stress-related disorders: reversal of corticosterone-induced changes in cortical neurons. Abstract [Details] |
Professional Activities
Honours and Awards
| Year | Title | Awarding Body | |
|---|---|---|---|
| 2016 | Research Supervisor of the Year, UCC | University College Cork | |
| 2016 | Professional Development Award for young scientists who demonstrate scientific merit and excellence in their research. | Society for Neuroscience | |
| 2015 | Prize for Oral Presentation, Neuroscience Ireland Conference, Dublin | Neuroscience Ireland | |
| 2013 | Prize for best poster, Annual Neuroscience Ireland conference, Cork | Neuroscience Ireland | |
| 2012 | SFI Investigator Award | Science Foundation Ireland | |
| 2012 | Prize for best Poster, Annual Neuroscience Ireland conference, RSCI, Dublin | Neuroscience Ireland | |
| 2011 | Prize for Best Poster, Annual Neuroscience Ireland conference, NUI, Maynooth | Neuroscience Ireland | |
| 2009 | Prize for Oral Presentation, Translational Health Research conference, UCC | College of Medicine and Health, University College Cork | |
| 2008 | National Academy (NAIRTL) award for the Integreation of Research and Teaching and Learning | NAIRTL | |
| 2007 | Prize for Best Poster, Health Research Day, University College Cork | College of Medicine and Health, UCC | |
| 2006 | Prize for Best Poster, Royal Academy of Medicine in Ireland, Biomedical Section | Royal Academy of Medicine in Ireland | |
| 2004 | Prize for Best Poster, Anatomical Society of Great Britain and Ireland meeting, Cork | Anatomical Society of Great Britain and Ireland | |
| 2003 | Prize for Best Poster, National Neuroscience Network meeting | National Neuroscience Network |
Professional Associations
| Association | Function | From / To | |
|---|---|---|---|
| Neuroscience Ireland | Member | / | |
| International Behavioural Neuroscience Society | Member | 03-FEB-20 / | |
| Psychoneuroimmunology Research Society (PNIRS) | Member | / | |
| Society for Neuroscience (SFN) | Member | / |
Patents
| Patent Number | Title | Granted | |
|---|---|---|---|
| Medical Compositions | 01-JAN-11 | ||
| Treatment of Ubiquitin-Proteasome system dysfunction related disorders | 01-JAN-11 | ||
| 10/894649 | Pharmaceutically acceptable phosphate-glycerol carrying bodies and uses relating to Parkinson's disease | 19-JUL-04 | |
| 11/227,984 | Multiple Sclerosis Treatment | 14-SEP-05 |
Conference Contributions
| Year | Publication | |
|---|---|---|
| (2019) | PsychoNeuroImmunology Research Society (PNIRS), C. M. Hueston, J. D. O’Leary, D. A. Kozareva, C. S. O’Leime, A.E. Hoban, L. C. Pawley, O. F. O’Leary, J. F. Cryan, Y. M. Nolan (2019) Differential effects of chronic neuroinflammation and exercise on hippocampal neurogenesis-associated behaviour through the lifespan. PsychoNeuroImmunology Research Society (PNIRS), . [Details] | |
| (2019) | New Horizon's in Medical Research, "Kevin Cusack, Caitriona Scaife, Danka Kozareva, Jane English, and Yvonne M. Nolan " (2019) Developmental profile of hippocampal neuroplasticity in adolescence: lessons from animal studies. [Poster Presentation], New Horizon's in Medical Research, Ireland . [Details] | |
| (2015) | New Horizons – Translational Research Conference, Levone BR, O’Leime C, Nolan YM, Cryan JF, O’Leary, OF (2015) Corticosterone differentially affects neural progenitor cells derived from specific areas of the longitudinal axis of the hippocampus. [Invited Lectures (Conference)], New Horizons – Translational Research Conference, Ireland . [Details] | |
| (2014) | Keystone Symposium Adult Neurogenesis, Ryan SM, Nolan YM (2014) Interleukin-1 attenuates exercise-induced adult hippocampal neurogenesis. [Invited Lectures (Conference)], Keystone Symposium Adult Neurogenesis, Stockholm, Sweden . [Details] | |
| (2014) | Molecular Medicine Ireland Education and Training Annual Scientific Meeting, Dolan, E. Nolan, Y.M., Sullivan, A.M. (2014) Characterisation of cognitive deficits in an alpha-synuclein model of Parkinson’s disease. [Invited Lectures (Conference)], Molecular Medicine Ireland Education and Training Annual Scientific Meeting, Trinity College Dublin . [Details] | |
| (2014) | Brain, Behavior, and Immunity, C.M.Hueston, B.R.Amels, J.D.O’Leary, S.M.Ryan, J.F.Cryan, Y.M.Nolan (2014) Lentiviral over-expression of interleukin-1 beta in the hippocampus induces cognitive deficits: Selective reversal by voluntary exercise throughout adolescence. [Invited Lectures (Conference)], Brain, Behavior, and Immunity, Unknown . [Details] | |
| (2014) | RAMI (Biomedical Science), Magee R, Nolan YM, Downer EJ (2014) Assessment of inflammatory activity in Multiple Sclerosis lesions. [Invited Lectures (Conference)], RAMI (Biomedical Science), UCD, Dublin . [Details] | |
| (2014) | EURON workshop: New Targets in Neurodegenerative Diseases, Dolan, E. Nolan, Y.M., Sullivan, A.M. (2014) Motor effects of unilateral and bilateral lesions induced by viral vector-mediated overexpression of alpha-synuclein in a rodent model of Parkinson’s disease. [Invited Lectures (Conference)], EURON workshop: New Targets in Neurodegenerative Diseases, Braga, Portugal . [Details] | |
| (2014) | Society for Neuroscience Annual Meeting, Hueston CM, Ryan SM, Amels BR, Cryan JF, Nolan YM (2014) Interactions between interleukin-1beta and short-term exercise on hippocampal neurogenesis: implications for cognitive function in the adult mouse. [Invited Lectures (Conference)], Society for Neuroscience Annual Meeting, Washington DC, USA . [Details] | |
| (2014) | 4th Annual meeting of Frontiers in Neurology, Yap S-M, Magee R, Nolan YM, Downer EJ (2014) Neuropathological analysis of human post-mortem Multiple Sclerosis brain tissue. [Invited Lectures (Conference)], 4th Annual meeting of Frontiers in Neurology, Dublin, Ireland . [Details] | |
| (2014) | Neuroscience Ireland Young Neuroscientists Symposium, O’Leary JD, Hueston CM, Kozareva D, O’Leary OF, Cryan JF, Nolan YM (2014) Role of the nuclear receptor TLX in cognition during adolescence and adulthood. [Invited Lectures (Conference)], Neuroscience Ireland Young Neuroscientists Symposium, Trinity College Dublin . [Details] | |
| (2014) | NECTAR, Yvonne M. Nolan (2014) Modulation of endogenous stem cells for hippocampal-dependant cognition. [Invited Lectures (Conference)], NECTAR, Galway, Ireland . [Details] | |
| (2014) | Psychoneuroimmunology Research Society meeting, Hueston CM, Amels BR, O’Leary JD, Ryan SM, Cryan JF, Nolan YM (2014) Lentiviral over-expression of interleukin-1 beta in the hippocampus induces cognitive deficits: Selective reversal by voluntary exercise throughout adolescence. [Invited Lectures (Conference)], Psychoneuroimmunology Research Society meeting, Philadelphia, USA . [Details] | |
| (2014) | Molecular Medicine Ireland Education and Training Annual Scientific Meeting, Dolan, E. Nolan, Y.M., Sullivan, A.M. (2014) Cognitive dysfunction in alpha-synuclein animal models of Parkinson’s disease. [Invited Lectures (Conference)], Molecular Medicine Ireland Education and Training Annual Scientific Meeting, Trinitry College Dublin . [Details] | |
| (2014) | Irish Journal of Medical Science, Kelly, M,Yssel, JD,Connor, T,Nolan, Y,Harkin, A (2014) Characterisation of a novel rat model of Parkinson's disease, combining intrastriatal 6-hydroxydopamine and intranigral lipopolysaccharide. [Invited Lectures (Conference)], Irish Journal of Medical Science, Ireland . [Details] | |
| (2014) | Keystone Symposium Adult Neurogenesis, Kozareva DA, Cryan JF, Nolan YM (2014) TLX, a regulator of neural stem cell self-renewal, is required for microglial integrity in the adult mouse dentate gyrus. [Invited Lectures (Conference)], Keystone Symposium Adult Neurogenesis, Stockholm, Sweden . [Details] | |
| (2014) | NECTAR 2014, Nolan Y.M., O'Brien I.S., Toulouse A. (2014) TNFα inhibits survival of midbrain neural precursor cells: an antiinflammatory role for Nurr1?. [Invited Lectures (Conference)], NECTAR 2014, Galway, Ireland , 27-NOV-14 - 28-NOV-14. [Details] | |
| (2013) | 8th Annual Neuroscience Ireland conference, Yssel JD, Kelly M, Connor TJ, Nolan YM, Harkin AJ (2013) Characterisation of a novel rat model of parkinson's disease, combining intrastriatal 6-hydroxydopamine and intranigral lipopolysaccharide. [Invited Lectures (Conference)], 8th Annual Neuroscience Ireland conference, University College Cork . [Details] | |
| (2013) | 3D O-2 imaging in the neuronal spheroids, Dmitriev, RI,Zhdanov, AV,Nolan, YM,Papkovsky, DB (2013) FASEB JOURNAL. [Invited Lectures (Conference)], 3D O-2 imaging in the neuronal spheroids, TBC . [Details] | |
| (2013) | 8th Annual Neuroscience Ireland conference, Green HF, Nolan YM (2013) The effect of il-1beta and gsk-3beta-inhibtion on tlx expression in embryonic rat hippocampal neural precursor cells. [Invited Lectures (Conference)], 8th Annual Neuroscience Ireland conference, University College Cork . [Details] | |
| (2013) | 8th Annual Neuroscience Ireland conference, Ryan SM, O’Connor C, Keeshan K, Nolan YM (2013) Interleukin-1beta attenuates exercise-induced adult hippocampal neurogenesis. [Invited Lectures (Conference)], 8th Annual Neuroscience Ireland conference, University College Cork . [Details] | |
| (2013) | 8th Annual Neuroscience Ireland conference, Dmitriev RI, Zhdanov AV, Nolan YM, Papkovsky DB (2013) An imaging method to analyse o2 distribution in live neurospheres. [Invited Lectures (Conference)], 8th Annual Neuroscience Ireland conference, University College Cork . [Details] | |
| (2013) | 8th Annual Neuroscience Ireland conference, Magee R, Nolan YM, Downer EJ (2013) Assessment of inflammatory activity in multiple sclerosis lesions and normal-appearing white matter. [Invited Lectures (Conference)], 8th Annual Neuroscience Ireland conference, University College Cork . [Details] | |
| (2013) | 8th Neuroscience Ireland Annual Conference, Collins L.M., O'Keeffe G.W., Gavin A.M., Wyatt S.L., Sullivan A.M., Toulouse A., Nolan Y.M. (2013) Expression of endogenous Mkp-1 in the adult rat nigrostriatal system following a unilateral 6-hydroxydopamine striatal and medial forebrain lesion. [Poster Presentation], 8th Neuroscience Ireland Annual Conference, University College Cork, Ireland , 12-SEP-13 - 13-SEP-13. [Details] | |
| (2012) | Neuroscience Ireland Conference, Dublin, Walsh S, Keeshan K, Nolan Y.M., O'Keeffe G.W., Sullivan, A.M. (2012) The effect of IL-1R1 shRNA intra-nigral administration in a hemi-parkinsonian 6-hydroxydopamine rat model. Irish J. Med. Sci. [Invited Lectures (Conference)], Neuroscience Ireland Conference, Dublin, Ireland . [Details] | |
| (2012) | Route28 Summit in Adult neurogenesis and neurodegenerative disease, Ryan SM, Nolan YM (2012) The role of the IL-1 type 1 receptor in the life death and differentiation of adult hippocampal neural precursor cells. [Invited Lectures (Conference)], Route28 Summit in Adult neurogenesis and neurodegenerative disease, Frauenchiemsee, Germany . [Details] | |
| (2012) | 7th Neuroscience Ireland Annual Conference, Collins L.M., O'Keeffe G.W., Long-Smith C.M., Sullivan A.M., Toulouse A., Nolan Y.M. (2012) Mitogen-activated protein kinase phosphatase (Mkp)-1 promotes the morphological development of midbrain dopaminergic neurons. [Invited Lectures (Conference)], 7th Neuroscience Ireland Annual Conference, Royal College of Surgeons Ireland , 05-SEP-12 - 06-SEP-12. [Details] | |
| (2011) | 8th IBRO World Congress of Neuroscience, O’Brien, I., Sullivan, A.M., Nolan, Y.M., Toulouse, A. (2011) Expression of the 2F7 epitope in the rat embryo, and adult brain. [Invited Lectures (Conference)], 8th IBRO World Congress of Neuroscience, Florence, Italy , 14-JUL-11 - 18-JUL-11. [Details] | |
| (2011) | EFFECT OF INTERLEUKIN-1 beta AND 6-HYDROXYDOPAMINE ON MKP-1 EXPRESSION IN EMBRYONIC RAT VENTRAL MESENCEPHALIC PRECURSOR CELLS, Collins, LM,Toulouse, A,Nolan, YM (2011) IRISH JOURNAL OF MEDICAL SCIENCE. [Invited Lectures (Conference)], EFFECT OF INTERLEUKIN-1 beta AND 6-HYDROXYDOPAMINE ON MKP-1 EXPRESSION IN EMBRYONIC RAT VENTRAL MESENCEPHALIC PRECURSOR CELLS, Ireland . [Details] | |
| (2011) | 8th IBRO World Congress of Neuroscience, Collins L.M., Toulouse A., Nolan Y.M. (2011) Effect of 6-hydroxydopamine on MKP-1 expression in differentiated embryonic rat ventral mesencephalic neural precursor cells. [Poster Presentation], 8th IBRO World Congress of Neuroscience, Florence, Italy , 14-JUL-11 - 18-JUL-11. [Details] | |
| (2011) | 8th IBRO World Congress of Neuroscience, Ryan S, Nolan YM (2011) IL-1beta negatively regulates expression of the orphan nuclear receptor TLX in adult rat hippocampal neural precursor cells in a dose-dependent manner. [Invited Lectures (Conference)], 8th IBRO World Congress of Neuroscience, Florence, Italy , 14-JUL-11 - 18-JUL-11. [Details] | |
| (2011) | 41st Annual Meeting of the Society for Neuroscience, Collins L.M., Toulouse A., Nolan Y.M. (2011) Mitogen-activated protein kinase phosphatase-1 (MKP-1) expression in 6-hydroxydopamine-treated embryonic rat mesencephalic neural precursor cells. [Poster Presentation], 41st Annual Meeting of the Society for Neuroscience, Washington DC , 12-NOV-11 - 16-NOV-11. [Details] | |
| (2011) | 6th Neuroscience Ireland 2011, Treacy E, Green HF, O'Keeffe GW, Nolan Y (2011) The effects of IL-1beta on cell fate determination of embryonic rat hippocampal neural precursor cells. [Invited Lectures (Conference)], 6th Neuroscience Ireland 2011, Maynooth, Ireland , 01-SEP-11 - 02-SEP-11. [Details] | |
| (2011) | The Physiological Society, Cellular and Integrative Neuroscience, Ryan S, Nolan YM (2011) The role of the orphan nuclear receptor TLX in IL-1beta-induced changes in proliferation of adult rat hippocampal neural precursor cells in vitro. [Invited Lectures (Conference)], The Physiological Society, Cellular and Integrative Neuroscience, London, UK , 06-APR-11 - 08-APR-11. [Details] | |
| (2011) | EFFECT OF INTERLEUKIN-1BETA ON EXPRESSION OF THE ORPHAN NUCLEAR RECEPTOR TLX IN ADULT RAT HIPPOCAMPAL NEURAL PRECURSOR CELLS, Ryan, S,Nolan, Y (2011) IRISH JOURNAL OF MEDICAL SCIENCE. [Invited Lectures (Conference)], EFFECT OF INTERLEUKIN-1BETA ON EXPRESSION OF THE ORPHAN NUCLEAR RECEPTOR TLX IN ADULT RAT HIPPOCAMPAL NEURAL PRECURSOR CELLS, Ireland . [Details] | |
| (2011) | 4th Annual Neuroscience Ireland Conference, Green HF, Nolan YM (2011) The effect of IL-1beta on embryonic rat hippocampal neural progenitor cell differentiation: role of GSK3beta. [Invited Lectures (Conference)], 4th Annual Neuroscience Ireland Conference, University College Dublin , 02-SEP-10 - 03-SEP-10. [Details] | |
| (2011) | THE EFFECT OF IL-1 beta ON EMBRYONIC RAT HIPPOCAMPAL NEURAL PROGENITOR CELL DIFFERENTIATION: ROLE OF GSK-3 beta, Green, HF,Nolan, Y (2011) IRISH JOURNAL OF MEDICAL SCIENCE. [Invited Lectures (Conference)], THE EFFECT OF IL-1 beta ON EMBRYONIC RAT HIPPOCAMPAL NEURAL PROGENITOR CELL DIFFERENTIATION: ROLE OF GSK-3 beta, Ireland . [Details] | |
| (2011) | 4th Annual Neuroscience Ireland Conference, Ryan S, Nolan YM (2011) Effect of Interleukin-1beta on expression of the orphan nuclear receptor TLX in adult rat hippocampal neural precursor cells. [Invited Lectures (Conference)], 4th Annual Neuroscience Ireland Conference, UCD , 02-SEP-10 - 03-SEP-10. [Details] | |
| (2011) | 6th Neuroscience Ireland Annual Conference, Collins L.M., Toulouse A., Nolan Y.M. (2011) 6-hydroxydopamine affects MKP-1 expression in differentiated embryonic rat ventral mesencephalic neural precursor cells. [Poster Presentation], 6th Neuroscience Ireland Annual Conference, National University of Ireland Maynooth , 01-SEP-11 - 02-SEP-11. [Details] | |
| (2010) | Neuroscience Ireland Conference, Dublin, Ryan, S., Keohane, A., Maloney, E., Sullivan, A.M., Nolan, Y. (2010) Effects of TNF-alpha on proliferation and differentiation of embryonic rat hippocampal neural precursor cells: a role for Hes1. [Invited Lectures (Conference)], Neuroscience Ireland Conference, Dublin, Ireland . [Details] | |
| (2010) | Adult Neurogenesis: Structure and function, Germany, Ryan S, Nolan YM ; (2010) Effect of IL-1beta on expression of the nuclear receptor TLX in adult rat hippocampal neural precursor cells. [Invited Lectures (Conference)], Adult Neurogenesis: Structure and function, Germany, TBC . [Details] | |
| (2010) | Neuroscience Ireland, TCD, Dublin, Green HF, Nolan YM; (2010) The role of GSK-3β in inflammation induced changes in embryonic rat hippocampal cell fate. [Invited Lectures (Conference)], Neuroscience Ireland, TCD, Dublin, Ireland . [Details] | |
| (2010) | Keystone Symposium Nuclear Receptors: Development, Physiology and Disease, Green, HF; Ryan,S; Nolan, YM; (2010) GSK-3beta regulates expression of the nuclear receptor TLX during interleukin-1eta-induced changes in hippocampal neural stem cell fate. [Invited Lectures (Conference)], Keystone Symposium Nuclear Receptors: Development, Physiology and Disease, TBC . [Details] | |
| (2010) | Neuroscience Ireland Conference, Dublin, Ryan, S., Keohane, A., Maloney, E., Sullivan, A.M., Nolan, Y. (2010) Effects of tumour necrosis factor-a on proliferation and differentation of embryonic rat hippocampal neural precursor cells: a role for HES1. [Invited Lectures (Conference)], Neuroscience Ireland Conference, Dublin, Ireland . [Details] | |
| (2010) | THE ROLE OF GSK-3 beta IN INFLAMMATION INDUCED CHANGES IN EMBRYONIC RAT HIPPOCAMPAL CELL FATE, Green, HF,Nolan, Y (2010) IRISH JOURNAL OF MEDICAL SCIENCE. [Invited Lectures (Conference)], THE ROLE OF GSK-3 beta IN INFLAMMATION INDUCED CHANGES IN EMBRYONIC RAT HIPPOCAMPAL CELL FATE, Ireland . [Details] | |
| (2010) | European College of Neuropsychopharmacology, Green HF, Nolan YM ; (2010) GSK-3beta inhibition blocks the effect of IL-1beta on hippocampal neural precursor cell differentiation. [Invited Lectures (Conference)], European College of Neuropsychopharmacology, TBC . [Details] | |
| (2010) | Adult Neurogenesis: Structure and function, Germany, Green HF, Nolan YM; (2010) Effect of IL-1beta on embryonic hippocampal neural progenitor cell proliferation and differentiation. [Invited Lectures (Conference)], Adult Neurogenesis: Structure and function, Germany, TBC . [Details] | |
| (2010) | Glycogen synthase kinase-3 beta inhibition blocks the effect of IL-1 beta on hippocampal neural precursor cell differentiation, Green, H,Nolan, Y (2010) EUROPEAN NEUROPSYCHOPHARMACOLOGY. [Invited Lectures (Conference)], Glycogen synthase kinase-3 beta inhibition blocks the effect of IL-1 beta on hippocampal neural precursor cell differentiation, TBC . [Details] | |
| (2010) | Society for Neuroscience, San Diego, USA, Nolan, YM; Green, HF; Ryan, S ; (2010) Effect of IL-1beta on expression of the orphan nuclear receptor TLX in embryonic rat hippocampal neural precursor cells. [Invited Lectures (Conference)], Society for Neuroscience, San Diego, USA, San Diego USA . [Details] | |
| (2009) | Translational Health Conference, UCC, Green HF, Nolan Y ; (2009) The effect of IL-1β on the expression of glycogen synthase kinase-3beta in hippocampal neural precursor cells. [Invited Lectures (Conference)], Translational Health Conference, UCC, Ireland . [Details] | |
| (2009) | International conference on Alzheimer's and Parkinson's diseases, Long, C., Sullivan, A.M., Nolan, Y. (2009) The effect of pharmacological and endogenous p38 inhibition on 6-hydroxydopamine-treated rat ventral mesencephalic neurons in vitro. [Invited Lectures (Conference)], International conference on Alzheimer's and Parkinson's diseases, Prague, Czech Republic . [Details] | |
| (2009) | The influence of microglia on the pathogenesis of Parkinson's disease, Long-Smith, CM,Sullivan, AM,Nolan, YM (2009) PROGRESS IN NEUROBIOLOGY. [Invited Lectures (Conference)], The influence of microglia on the pathogenesis of Parkinson's disease, t . [Details] | |
| (2009) | Translational Health Conference, UCC, Collins L., Long C., Sullivan A., Toulouse A., Nolan Y. (2009) The effect of pharmacological and endogenous p38 inhibition on 6-hydroxydopamine-treated rat ventral mesencephalic neurons in vitro. [Poster Presentation], Translational Health Conference, UCC, Ireland . [Details] | |
| (2009) | Translational Health Conference, UCC, Ryan S, Maloney E, Keohane A, Sullivan AM, Nolan YM ; (2009) Tumour necrosis factor-α affects the proliferation and differentiation of embryonic rat hippocampal neural precursor cells. [Invited Lectures (Conference)], Translational Health Conference, UCC, Ireland . [Details] | |
| (2008) | 2nd Neuroscience Ireland Conference, NUI Galway, Keohane, A., Sullivan, A.M., Nolan, Y. (2008) IL-1 receptor antagonist prevents the effects of the pro-inflammatory cytokine, IL-1β on differentiating embryonic rat hippocampal neuronal precursor cells. [Invited Lectures (Conference)], 2nd Neuroscience Ireland Conference, NUI Galway, Ireland . [Details] | |
| (2008) | International Neuroimmunology Symposium, Dublin, Long, C., Sullivan, A.M., Nolan, Y. (2008) IL-1β released from LPS-stimulated cortical glial cultures exacerbates 6-OHDA-induced dopaminergic neuronal cell death in vitro. [Invited Lectures (Conference)], International Neuroimmunology Symposium, Dublin, Ireland . [Details] | |
| (2008) | International Neuroimmunology Symposium, Dublin, Ireland, Keohane, A., Sullivan, A.M., Nolan, Y. (2008) The effect of the pro-inflammatory cytokine, TNFα, on the proliferation and differentiation of embryonic hippocampal neural cells. [Invited Lectures (Conference)], International Neuroimmunology Symposium, Dublin, Ireland, Ireland . [Details] | |
| (2008) | 2nd Neuroscience Ireland Conference, NUI Galway, H.F. Green, Y. Nolan; (2008) The effect of the pro-inflammatory cytokine IL-1beta on the expression of glycogen synthase kinase-3beta in hippocampal neural precursor cells. [Invited Lectures (Conference)], 2nd Neuroscience Ireland Conference, NUI Galway, Ireland . [Details] | |
| (2008) | Neuroscience Ireland Conference, Galway, Ryan, S., Maloney, E., Keohane, A., Sullivan, A.M., Nolan, Y.M. (2008) TNF-a affects the proliferation and differentiation of embryonic rat hippocampal neural precursor cells. [Invited Lectures (Conference)], Neuroscience Ireland Conference, Galway, Ireland . [Details] | |
| (2008) | The effects of the pro-intlanumatory cytokine TNF-alpha on the proliferation and differentiation of embryonic rat hippocampal neural precursor cells, Keohane, A,Sullivan, AM,Nolan, Y (2008) JOURNAL OF NEUROIMMUNOLOGY. [Invited Lectures (Conference)], The effects of the pro-intlanumatory cytokine TNF-alpha on the proliferation and differentiation of embryonic rat hippocampal neural precursor cells, TBC . [Details] | |
| (2008) | IL-1 beta released from LPS-stimulated cortical glial cultures exacerbates 6-OHDA-induced dopaminergic neuronal cell death in vitro, Long, CM,Sullivan, AM,Nolan, Y (2008) JOURNAL OF NEUROIMMUNOLOGY. [Invited Lectures (Conference)], IL-1 beta released from LPS-stimulated cortical glial cultures exacerbates 6-OHDA-induced dopaminergic neuronal cell death in vitro, TBC . [Details] | |
| (2008) | Neuroscience Ireland Conference, Galway, Long, C., Sullivan, A.M., Nolan, Y. (2008) The role of IL-1b in mediating the effects of LPS-stimulated rat glia on dopaminergic neuronal death in vitro. [Invited Lectures (Conference)], Neuroscience Ireland Conference, Galway, Ireland . [Details] | |
| (2008) | International Neuroimmunology Symposium, Dublin, Long, C., Sullivan, A.M., Nolan, Y. (2008) Il-1 Beta Released From Lps-Stimulated Cortical Glial Cultures Exacerbates 6-Ohda-Induced Dopaminergic Neuronal Cell Death In Vitro. [Invited Lectures (Conference)], International Neuroimmunology Symposium, Dublin, Ireland . [Details] | |
| (2007) | XVIIth World Federation of Neurology World Congress on Parkinson's Disease and Related Disorders, Amsterdam, Long, C., Sullivan, A.M., Nolan, Y. (2007) The effect of p38 inhibition on the survival of 6-hydroxydopamine-treated rat ventral mesencephalic neurons in vitro. [Invited Lectures (Conference)], XVIIth World Federation of Neurology World Congress on Parkinson's Disease and Related Disorders, Amsterdam, Netherlands . [Details] | |
| (2007) | British Neuroscience Association meeting, Harrogate, UK. Brit. Neurosci. Assoc, Long, C., Sullivan, A.M., Nolan, Y; (2007) The effect of conditioned media from LPS-stimulated rat mixed glial cultures on 6-OHDA-treated rat ventral mesencephalic neurons in vitro. Prize for Best Poster. [Invited Lectures (Conference)], British Neuroscience Association meeting, Harrogate, UK. Brit. Neurosci. Assoc, UK . [Details] | |
| (2007) | British Neuroscience Association Meeting, Keohane, A., Sullivan, A.M., Nolan, Y. (2007) The effect of pro-inflammatory cytokines, IL-1β and TNFα on embryonic rat hippocampal neuronal precursor cells. [Invited Lectures (Conference)], British Neuroscience Association Meeting, UK . [Details] | |
| (2007) | Parkinsonism Relat Disord 13 Suppl 2: S134 XVIIth World Federation of Neurology World Congress on Parkinson's Disease and Related Disorders, Amsterdam, C. Long, A.M. Sullivan, Y.M. Nolan; (2007) The effect of p38 inhibition on the survival of 6-hydroxydopamine-treated rat ventral mesencephalic neurons in vitro. [Invited Lectures (Conference)], Parkinsonism Relat Disord 13 Suppl 2: S134 XVIIth World Federation of Neurology World Congress on Parkinson's Disease and Related Disorders, Amsterdam, Netherlands . [Details] | |
| (2007) | 19th National Meeting of the British Neuroscience Association, Harrogate, Long, C., Sullivan, A.M., Nolan, Y. ; (2007) The effect of conditioned media from LPS-stimulated rat mixed glial cultures on 6-OHDA-treated rat ventral mesencephalic neurons in vitro. [Invited Lectures (Conference)], 19th National Meeting of the British Neuroscience Association, Harrogate, UK . [Details] | |
| (2006) | FENS Forum of Neuroscience, Vienna, Austria, Long, C., Sullivan, A.M., Nolan, Y. (2006) 6-hydroxydopamine induces a direct neurotoxic effect on embryonic rat midbrain dopaminergic neurons independent of microglial activation in vitro. [Invited Lectures (Conference)], FENS Forum of Neuroscience, Vienna, Austria, Vienna, Austria . [Details] | |
| (2006) | Society for Neuroscience meeting, Atlanta, USA, Crotty,S., Fitzgerald, P., Mandel,A.,Bolton, A.E., Sullivan, A.M., Nolan, Y. (2006) Treatment with a novel phospholipid-based drug formulation prevents behavioural deficits induced by proteasome inibition: implications for Parkinson's disease. [Invited Lectures (Conference)], Society for Neuroscience meeting, Atlanta, USA, Atlanta, USA . [Details] | |
| (2006) | Royal Academy of Medicine in Ireland Biomedical Section Winter Meeting, Dublin, Long, C., Nolan, Y.M., Sullivan, A.M. (2006) Effects of 6-hydroxydopamine on the survival of embryonic rat midbrain dopamine neurons in vitro. Poster Prize. [Invited Lectures (Conference)], Royal Academy of Medicine in Ireland Biomedical Section Winter Meeting, Dublin, Ireland . [Details] | |
| (2006) | Neuroscience Ireland Meeting, Cork. Irish J Med Sci, Crotty S, Fitzgerald P, Harris DM, Fisher A, Mandel A, Bolton AE, Sullivan AM, Nolan Y ; (2006) Neuroprotective evidence of a novel phospholipid-based drug formulation in a rat model of parkinson¿s disease. [Invited Lectures (Conference)], Neuroscience Ireland Meeting, Cork. Irish J Med Sci, Ireland . [Details] | |
| (2006) | New Horizon's in Medical Research, Keohane, A., Sullivan, A.M., Nolan, Y. (2006) Characterisation of embryonic rat hippocampal neuronal precursor cells in neurosphere cultures. [Invited Lectures (Conference)], New Horizon's in Medical Research, Cork . [Details] | |
| (2006) | Neuroscience Ireland Meeting, Cork, Long, C., Sullivan, A.M., Nolan, Y. (2006) 6-hydroxydopamine induces a direct neurotoxic effect on embryonic rat midbrain dopaminergic neurons independent of microglial activation in vitro. [Invited Lectures (Conference)], Neuroscience Ireland Meeting, Cork, Ireland . [Details] | |
| (2006) | Inaugural Neuroscience Ireland Meeting, Cork, Long C, Sullivan AM, Nolan Y ; (2006) 6-hydroxydopamine induces a direct neurotoxic effect on embryonic rat midbrain dopaminergic neurons independent of microglial activation in vitro. Ir. J. Med. Sci. 175(3) es1 P42. [Invited Lectures (Conference)], Inaugural Neuroscience Ireland Meeting, Cork, Ireland . [Details] | |
| (2006) | Royal Academy of Medicine in Ireland Biomedical Section Meeting, Dublin, Crotty, S., Fitzgerald, P., Harris, D.M., Fisher, A., Mandel, A., Bolton, A.E., Sullivan, A.M., Nolan, Y. (2006) 6-hydroxydopamine-induced p38 activation in rat nigral dopaminergic neurons is reduced by treatment with a novel phospholipid-based drug formulation. [Invited Lectures (Conference)], Royal Academy of Medicine in Ireland Biomedical Section Meeting, Dublin, Ireland . [Details] | |
| (2006) | Ir. J. Med. Sci. 175(3) es1 P36, Keohane A, Sullivan AM, Nolan Y ; (2006) Characterisation of embryonic rat hippocampal neuronal precursor cells in neurosphere cultures. [Invited Lectures (Conference)], Ir. J. Med. Sci. 175(3) es1 P36, Ireland . [Details] | |
| (2006) | Ir. J. Med. Sci. 175(3) es1 P17, Crotty S, Fitzgerald P, Harris DM, Fisher A, Mandel A, Bolton AE, Sullivan AM, Nolan Y ; (2006) Neuroprotective evidence of a novel phospholipid-based drug formulation in a rat model of parkinson's disease. [Invited Lectures (Conference)], Ir. J. Med. Sci. 175(3) es1 P17, Ireland . [Details] | |
| (2005) | International Congress on Parkinson’s Disease and Related Disorders, Berlin, Germany, Harris, D.M., Fisher, A., Mandel, A., Bolton, A.E., Sullivan, A.M., Nolan, Y. (2005) 6-hydroxydopamine-induced degeneration of rat nigral dopaminergic neurons and microglial activation is reduced by treatment with a novel phospholipid-based drug formulation. [Invited Lectures (Conference)], International Congress on Parkinson’s Disease and Related Disorders, Berlin, Germany, Berlin, Germany , 05-JUN-05 - 08-JUN-06. [Details] | |
| (2005) | Society for Neuroscience Abstracts 910.2, Martin DSD, Walsh M, Miller A, Nolan Y, Mandel A, Bolton AE, Lynch MA ; (2005) The age-related increase in microglial activation in the rat hippocampus is abrogated by a novel phospholipid-based drug formulation. [Invited Lectures (Conference)], Society for Neuroscience Abstracts 910.2, TBC . [Details] | |
| (2005) | . British Neuroscience Association Abstracts 8.05, Martin DSD, Walsh M, Miller AM, Nolan Y, Mandel A, Bolton A, Lynch MA (; (2005) A novel phospholipid-based drug formulation inhibits the age- and LPS-related increase in microglial activation. [Invited Lectures (Conference)], . British Neuroscience Association Abstracts 8.05, UK . [Details] | |
| (2005) | Society for Neuroscience meeting, Washington, USA, Fitzgerald, P., Harris, D.M., Crotty, S., Harkin, A., Mandel, A., Bolton, A.E., Sullivan, A.M., Nolan, Y. (2005) Treatment with a novel phospholipid-based drug formulation inhibits 6-hydroxydopamine-induced p38 activation in rat substantia nigra. [Invited Lectures (Conference)], Society for Neuroscience meeting, Washington, USA, Washington DC, USA , 11-DEC-05 - 16-NOV-05. [Details] | |
| (2005) | British Neuroscience Association Abstracts 8.07, Moore M, Nolan YM, Lynch MA. ; (2005) Treatment of aged rats with dexamethasone and vitamin D3 restores LTP; evidence of a role for IL-10. [Invited Lectures (Conference)], British Neuroscience Association Abstracts 8.07, UK . [Details] | |
| (2005) | Society for Neuroscience Abstracts 910.1, Nally RF, Linden J, McCartney Y, Nolan Y, Walsh M, Lynch M ; (2005) Increased IL-18 concentration and upregulation of microglial activation in hippocampus of middle-aged rats are accompanied by attenuated long-term potentiation in dentate gyrus. [Invited Lectures (Conference)], Society for Neuroscience Abstracts 910.1, TBC . [Details] | |
| (2005) | National Symposium of The Irish Research Council for Science, Engineering and Technology, Long C, Nolan Y.M., Sullivan, A.M. (2005) The role of inflammation and p38 in 6-OHDA-induced dopaminergic neuronal death–implications for Parkinson’s. 324. [Invited Lectures (Conference)], National Symposium of The Irish Research Council for Science, Engineering and Technology, Ireland . [Details] | |
| (2005) | Ir. J. Med. Sci. 174(1) es2 P26, Harris DM, Fisher A, Harkin AJ, Bolton AE, Sullivan AM, Nolan YM; (2005) Novel phospholipid-based drug formulation prevents degeneration of dopaminergic neurons from substantia nigra in a rat model of Parkinson¿s disease. [Invited Lectures (Conference)], Ir. J. Med. Sci. 174(1) es2 P26, Ireland . [Details] | |
| (2005) | Royal Academy of Medicine in Ireland, Biomedical Section, Harris DM, Fisher A, Harkin AJ, Bolton AE, Sullivan AM, Nolan YM; (2005) Novel phospholipid-based drug formulation prevents degeneration of dopaminergic neurons from substantia nigra in a rat model of Parkinson’s disease. [Invited Lectures (Conference)], Royal Academy of Medicine in Ireland, Biomedical Section, Galway, Ireland , 16-JUN-05 - 17-JUN-05. [Details] | |
| (2005) | Royal Academy of Medicine in Ireland Biomedical Section Meeting, Dublin, Fitzgerald, P., Harris, D.M., Crotty, S., Fisher, A., Mandel, A., Bolton, A.E., Sullivan, A.M., Nolan, Y.M. (2005) 6-hydroxydopamine-induced degeneration of rat nigral dopaminergic neurons and microglial activation is reduced by treatment with a novel phospholipid-based drug formulation. [Invited Lectures (Conference)], Royal Academy of Medicine in Ireland Biomedical Section Meeting, Dublin, Ireland . [Details] | |
| (2005) | Society for Neuroscience meeting, Washington, USA, O’Sullivan, D.B., Harrison, P.T., Nolan, Y.M., Sullivan, A.M. (2005) Prevention of apoptosis in cultured dopaminergic neurons by GDNF and GDF5. [Invited Lectures (Conference)], Society for Neuroscience meeting, Washington, USA, Washington DC, USA , 12-NOV-05 - 16-NOV-05. [Details] | |
| (2004) | Federation of European Neuroscience, Martin D, Walsh M, Nolan Y, Mandel A, Bolton A, Campbell V, Lynch MA; (2004) Phospholipid microparticles-containing phosphatidylglycerol prevent the age-related impairment in long-term potentiation in the rat dentate gyrus. [Invited Lectures (Conference)], Federation of European Neuroscience, Lisbon, Portugal , 10-JUL-04 - 14-JUL-04. [Details] | |
| (2004) | Society for Neuroscience, Martin DSD, Walsh M, Nolan Y, Mandel A, Bolton A, Lynch MA; (2004) Novel phospholipid-based drug formulation reverses the age-related increase in interleukin-1 in the rat hippocampus. [Invited Lectures (Conference)], Society for Neuroscience, San Diego, California , 23-OCT-04 - 27-OCT-04. [Details] | |
| (2004) | Society for Neuroscience, Nally RE, Walsh M, Nolan Y, Lynch MA; (2004) Age-related changes in the rat hippocampus and the effect of exogenously administered interleukin-1b. [Invited Lectures (Conference)], Society for Neuroscience, San Diego, California , 23-OCT-04 - 27-OCT-04. [Details] | |
| (2004) | Society for Neuroscience Meeting, San Diego, USA, Fisher, A., Harris, D.M., Harkin, A.J., Bolton, A.E., Sullivan, A.M., Nolan Y.M. (2004) Novel phospholipid-based drug formulation retards the 6-hydroxydopamine-induced degeneration of rat nigral dopaminergic neurons. [Invited Lectures (Conference)], Society for Neuroscience Meeting, San Diego, USA, San Diego, USA . [Details] | |
| (2004) | Federation of European Neuroscience, Lonergan PE, Martin DS, Nolan YM, Clarke RM, Kavanagh T, Horrobin DF, Lynch MA; (2004) Neuroprotective actions of eicosapentaenoic acid on lipopolysaccharide-induced dysfunction in rat hippocampus are mimicked by interleukin-4. [Invited Lectures (Conference)], Federation of European Neuroscience, Lisbon, Portugal , 10-JUL-04 - 14-JUL-04. [Details] | |
| (2004) | Federation of European Neuroscience, Nolan Y, Clarke RM, Lynch MA; (2004) Interleukin-4 (IL-4) blocks the inhibitory effect of IL-1b-induced signalling on long term potentiation (LTP) in rat hippocampus. [Invited Lectures (Conference)], Federation of European Neuroscience, Lisbon, Portugal , 10-JUL-04 - 14-JUL-04. [Details] | |
| (2004) | Federation of European Neuroscience, Lynch AM, Moore M, Nolan Y, Lynch MA; (2004) IL-10 confers neuroprotection in the rat hippocampus. [Invited Lectures (Conference)], Federation of European Neuroscience, Lisbon, Portugal , 10-JUL-04 - 14-JUL-04. [Details] | |
| (2003) | Royal Academy of Medicine in Ireland, Nolan Y, Vereker E, Lynch AM, Lynch MA; (2003) Evidence that accumulation of reactive oxygen species and activation of p38 mediates lipopolysaccharide-induced cell death in rat hippocampus. [Invited Lectures (Conference)], Royal Academy of Medicine in Ireland, Cork, Ireland , 15-JUN-03 - 16-JUN-03. [Details] | |
| (2003) | Physiological Society, Nolan Y, Vereker E, Lynch AM, Lynch MA; (2003) Evidence that accumulation of reactive oxygen species and activation of p38 mediates lipopolysaccharide-induced cell death in rat hippocampus. [Invited Lectures (Conference)], Physiological Society, Dublin, Ireland , 08-JUL-03 - 10-JUL-03. [Details] | |
| (2003) | Society for Neuroscience, USA, Barry CE, Nolan YM, Lynch MA; (2003) Activation of the c-jun N-terminal kinase mediates lipopolysaccharide-induced cell deterioration in rat hippocampus. [Invited Lectures (Conference)], Society for Neuroscience, USA, New Orleans USA , 08-NOV-03 - 12-NOV-03. [Details] | |
| (2003) | Society for Neuroscience, USA, Martin DSD, Walsh M, Nolan YM, Mandel A, Bolton AE, Campbell VA, Lynch MA; (2003) Phosphatidylglycerol-containing liposomes prevent the lipopolysaccharide-induced impairment in long-term potentiation in the rat dentate gyrus. [Invited Lectures (Conference)], Society for Neuroscience, USA, New Orleans, USA , 08-NOV-03 - 12-NOV-03. [Details] | |
| (2002) | Society for Neuroscience, USA, Lynch AM, Walsh C, Delaney A, Nolan Y, Campbell VA, Lynch MA; (2002) The lipopolysaccharide-induced increase in signaling in the hippocampus is abrogated by IL-10, a role for IL-1b?. [Invited Lectures (Conference)], Society for Neuroscience, USA, Orlando, Florida , 02-NOV-02 - 07-NOV-02. [Details] | |
| (2002) | Society for Neuroscience, USA, Nolan YM, Martin DSD, Bolton AE, Campbell VA, Lynch MA; (2002) Evidence of an anti-inflammatory effect of apoptotic mimetics on lipopolysaccharide-induced inhibition of long-term potentiation in the hippocampus. [Invited Lectures (Conference)], Society for Neuroscience, USA, Orlando, Florida , 02-NOV-02 - 07-NOV-02. [Details] | |
| (2002) | Annual Congress of the British Society of Immunology, Nolan YM, Martin DSD, Bolton AE, Campbell VA, Lynch MA; (2002) Evidence of an anti-inflammatory effect of apoptotic mimetics on lipopolysaccharide-induced inhibition of long-term potentiation in the hippocampus. [Invited Lectures (Conference)], Annual Congress of the British Society of Immunology, Harrogate, England , 03-DEC-02 - 06-DEC-02. [Details] | |
| (2001) | The Psychoneuroimmunology Research Society, Connor TJ, O’Sullivan J, Nolan Y, Leonard BE, Kelly JP; (2001) NG-Nitro-L-Arginine potentiates lipopolysaccharide-induced sickness behaviour by increasing TNF-a. [Invited Lectures (Conference)], The Psychoneuroimmunology Research Society, Utrecht, Netherlands , 16-MAY-01 - 19-MAY-01. [Details] | |
| (2001) | Society for Neuroscience, USA, Nolan Y, Bolton AE, Campbell VA, Lynch MA; (2001) Vasogen’s immune modulation therapy reduces inflammatory markers and attenuates lipopolysaccharide-induced cell death in rat cortical tissue. [Invited Lectures (Conference)], Society for Neuroscience, USA, San Diego, California , 10-NOV-01 - 15-NOV-01. [Details] | |
| (2000) | European College of Neuropsychopharmacology Congress, Kelly JP, Connor TJ, Nolan Y, Shen Y, Leonard BE; (2000) Differential effect of chronic antidepressant treatments on lipopolysaccharide-induced depressive-like behavioural symptoms and the pro-/anti-inflammatory cytokine balance. [Invited Lectures (Conference)], European College of Neuropsychopharmacology Congress, Munich, Germany , 09-SEP-00 - 13-SEP-00. [Details] | |
| (1999) | Psychoneuroimmunology Research Society Meeting, Nolan Y, Connor TJ, Kelly JP, Leonard BE; (1999) Nitric oxide synthase inhibition potentiates LPS-induced physiological and behavioural changes in the rat. [Invited Lectures (Conference)], Psychoneuroimmunology Research Society Meeting, Galveston, Texas , 28-APR-99 - 01-MAY-99. [Details] | |
| (1998) | Psychoneuroimmunology Research Society Meeting, Kelliher P, Nolan YM, Dredge K, Connor TJ, Kelly JP, Leonard BE; (1998) Effect of a variety of stressors on leucocyte subpopulations in the rat. [Invited Lectures (Conference)], Psychoneuroimmunology Research Society Meeting, Bristol, England , 28-APR-98 - 01-MAY-98. [Details] | |
| (1997) | Royal Academy of Medicine in Ireland Meeting, Nolan YM, Connor TJ, Kelly JP, Leonard BE; (1997) An acute lipopolysaccharide (LPS) challenge produces dose-dependent and serotype specific changes in neurochemical, endocrine and immune parameters in the rat. [Invited Lectures (Conference)], Royal Academy of Medicine in Ireland Meeting, Limerick, Ireland , 01-JUN-97 - 01-JUN-97. [Details] | |
| (2019) | British Neuroscience Association, Sarah Nicolas, Ciarán S. Ó Léime, Alan E. Hoban, Cara M. Hueston, John F. Cryan, and Yvonne M. Nolan. (2019) Does adolescent exposure to a cafeteria-diet potentiate the effect of neuroinflammation on memory during adulthood in rats?. [Poster Presentation], British Neuroscience Association, Ireland . [Details] | |
| (2019) | Older and Wiser: Child and adolescent brain development, Y. Nolan (2019) Older and Wiser: Child and adolescent brain development. [Invited Lectures (Workshops)], Older and Wiser: Child and adolescent brain development, Scoil Bhride, Crosshaven, Cork. Ireland . [Details] | |
| (2019) | Irish Gerontological Society, Yvonne Nolan, Eva McMullan, Jason Chan, Annalisa Selli (2019) Music Intervention on the Neurological Development on children with Down Syndrome (MINDDS). [Invited Oral Presentation], Irish Gerontological Society, Ireland . [Details] | |
| (2019) | British Neuroscience Association, Yvonne Nolan (2019) Chronic hippocampal inflammation and cognitive decline: neurogenesis-mediated mechanisms. [Invited Oral Presentation], British Neuroscience Association, Ireland . [Details] | |
| (2019) | APC Microbome Ireland, Yvonne Nolan (2019) Inflammation and exercise shaping hippocampal structure and cognitive function. [Invited Oral Presentation], APC Microbome Ireland, Ireland . [Details] | |
| (2019) | Atlantic Corridor Medical Student Research Conference, "Ciara O’Donoghue, Caitriona Long-Smith, Stefanie Grabrucker, Gerard Clarke, Suzanne Timmons and Yvonne M. Nolan" (2019) Assessment of differences in lifestyle factors and biological sex on cognition and inflammation in healthy older aged adults. [Poster Presentation], Atlantic Corridor Medical Student Research Conference, Ireland . [Details] | |
| (2019) | New Horizon's in Medical Research, Sarah Nicolas, Ciarán S. Ó Léime, Alan E. Hoban, Cara M. Hueston, John F. Cryan, and Yvonne M. Nolan. (2019) Does adolescent exposure to a cafeteria-diet potentiate the effect of neuroinflammation on memory during adulthood in rats?. [Poster Presentation], New Horizon's in Medical Research, Ireland . [Details] | |
| (2019) | British Neuroscience Association, "Erin K. Crowley, Stefanie Grabrucker, Caitriona Long-Smith, Cora O’Neill, Denise M. O’Gorman, and Yvonne M. Nolan" (2019) Influence of magnesium-rich marine mineral dietary supplementation on synaptic plasticity, neurogenesis and memory function in young and old rats. [Poster Presentation], British Neuroscience Association, Ireland . [Details] | |
| (2019) | British Neuroscience Association, "Lauren C. Pawley , Andrew McGovern, James O’Leary , Cara Heuston , Danka A. Kozareva, John F. Cryan, Olivia F. O’Leary , Yvonne M. Nolan " (2019) Differential effects of chronic neuroinflammation on adult and adolescent hippocampal neurogenesis. [Poster Presentation], British Neuroscience Association, Ireland . [Details] | |
| (2019) | Learning Connections, Eva McMullan-Glossop, Yvonne Nolan (2019) INSTRUMENTAL Introducing New Strategies of Teaching NeuRoscience Using Music to enhance EducatioN Through creAtive Learning. [Invited Oral Presentation], Learning Connections, Ireland . [Details] | |
| (2019) | New Horizon's in Medical Research, "Kevin Cusack, Caitriona Scaife, Danka Kozareva, Jane English, and Yvonne M. Nolan " (2019) Developmental profile of hippocampal neuroplasticity in adolescence: lessons from animal studies. [Poster Presentation], New Horizon's in Medical Research, Ireland . [Details] | |
| (2018) | European College of Neuropsychopharmacology (ECNP), Yvonne Nolan (2018) Inflammation and hippocampal neurogenesis – exercise as a mood and cognitive modulator. [Invited Oral Presentation], European College of Neuropsychopharmacology (ECNP), Spain . [Details] | |
| (2018) | New Horizon's in Medical Research, Lauren C. Pawley, James D. O’Leary, Cara M. Hueston, John F. Cryan, Olivia F. O’Leary, Yvonne M. Nolan (2018) Chronic Inflammatory Changes in Adult and Adolescent Hippocampal Neurogenesis. [Invited Oral Presentation], New Horizon's in Medical Research, Ireland . [Details] | |
| (2018) | EMBO, Danka A. Kozareva , Gerard M. Moloney, Alan E. Hoban, Valerio Rossini, Ken Nally, John F. Cryan, Yvonne M. Nolan (2018) The role of the orphan nuclear receptor TLX in neural stem cell-microglial crosstalk. [Poster Presentation], EMBO, Germany . [Details] | |
| (2017) | European Brain and Behaviour Society, O'Leary JD, Hoban AE, O'Leary OF, Cryan JF, Nolan YM (2017) DIFFERENTIAL EFFECTS OF EXERCISE DURING ADOLESCENCE AND ADULTHOOD ON COGNITION AND PLASTICITY. [Poster Presentation], European Brain and Behaviour Society, Spain , 08-SEP-17. [Details] | |
| (2017) | Neuroscience Ireland, Danka A. Kozareva, Olivia F. O'Leary, John F. Cryan, Yvonne M. Nolan (2017) Deletion of Tlx and social isolation impairs exercise-induced neurogenesis in the adolescent hippocampus. [Poster Presentation], Neuroscience Ireland, NUI Galway , 28-AUG-17. [Details] | |
| (2017) | ECNP workshop for Junior Scientists in Europe, Levone BR, Nolan YM, Cryan JF, O'Leary OF (2017) Region-specific effects of corticosterone on neural progenitors along the dorso-ventral axis of the hippocampus. [Poster Presentation], ECNP workshop for Junior Scientists in Europe, Nice, France . [Details] | |
| (2017) | Society for Neuroscience, O'Leary JD, Hoban AE, O'Leary OF, Cryan JF, Nolan YM (2017) Differential effects of exercise during adolescence and adulthood on cognition and plasticity. [Poster Presentation], Society for Neuroscience, United States of America , 12-NOV-17. [Details] | |
| (2017) | Society for Neuroscience, Ciarán S.Ó Léimea, Alan E.Hoban, Cara M.Hueston, Roman Stilling, Gerard Moloney, John F.Cryan, Yvonne M.Nolan (2017) The orphan nuclear receptor TLX regulates hippocampal transcriptome changes induced by IL-1β. [Poster Presentation], Society for Neuroscience, United States of America , 12-NOV-17. [Details] | |
| (2017) | AD/PDTM 2017, O’Donovan SM, Crowley E, Browne J, O’Sullivan O, O’Leary OF, Timmons S, Nolan YM, O’Toole PW, Clarke DJ, Hyland NP, Joyce SA, Sullivan AM, O’Neill C (2017) The brain ↔gut axis in Parkinson’s disease: defining gut pathology and the impact of exercise in the rAAV-α-synuclein rat model of PD AD/PDTM 2017, the 13th International Conference on Alzheimer's and Parkinson's Diseases and Related Neurological Disorders. [Invited Lectures (Conference)], AD/PDTM 2017, Vienna,Austria . [Details] | |
| (2017) | Society for Neuroscience, Danka A. Kozareva, Olivia F. O'Leary, John F. Cryan, Yvonne M. Nolan (2017) Deletion of Tlx and social isolation impairs exercise-induced neurogenesis in the adolescent hippocampus. [Poster Presentation], Society for Neuroscience, United States of America , 12-NOV-17. [Details] | |
| (2017) | European Brain and Behaviour Society, O'Leary JD, Hoban AE, O'Leary OF, Cryan JF, Nolan YM (2017) DIFFERENTIAL EFFECTS OF EXERCISE DURING ADOLESCENCE AND ADULTHOOD ON COGNITION AND PLASTICITY. [Poster Presentation], European Brain and Behaviour Society, Spain , 08-SEP-17. [Details] | |
| (2017) | Neuroscience Ireland, SM O’Donovan, EK Crowley, J Browne, O O’Sullivan, OF O’Leary, S Timmons, YM Nolan, PW O’Toole, DJ Clarke, NP Hyland, SA Joyce, AM Sullivan, C O’Neill (2017) Investigation of the brain gut axis in the rAAV-alpha-synuclein PD model: Reveals enteric nervous system pathology and alterations in the gut microbiome. [Poster Presentation], Neuroscience Ireland, NUI Galway , 24-AUG-17. [Details] | |
| (2017) | New Horizon's in Medical Research, Yvonne M. Nolan (2017) Lifestyle factors shaping hippocampal structure and function across the lifespan. [Invited Oral Presentation], New Horizon's in Medical Research, Ireland . [Details] | |
| (2017) | New Horizon's in Medical Research, Danka A.Kozareva, Cara M.Hueston, Ciarán S.Ó Léime, Suzanne Crotty, Pete rDocker, John F.Cryan, Yvonne M.Nolan (2017) Absence of the neurogenesis-dependent nuclear receptor TLX induces inflammation in the hippocampus. [Poster Presentation], New Horizon's in Medical Research, Ireland . [Details] | |
| (2017) | Neuroscience Ireland, Danka A. Kozareva, Olivia F. O'Leary, John F. Cryan, Yvonne M. Nolan (2017) Deletion of Tlx and social isolation impairs exercise-induced neurogenesis in the adolescent hippocampus. [Poster Presentation], Neuroscience Ireland, NUI Galway , 28-AUG-17. [Details] | |
| (2017) | Neurogastroenterology and Motiltiy, S O'Donovan, EK Crowley, J Browne, O O'Sullivan, OF O'Leary, S Timmons, YM Nolan, PW O'Toole, DJ Clarke, NP Hyland, SA Joyce, AM Sullivan, C O'Neill (2017) Investigation of the brain gut axis in the rAAV-alpha-synuclein PD model: Reveals enteric nervous system pathology and alterations in the gut microbiome. [Poster Presentation], Neurogastroenterology and Motiltiy, Cork Ireland . [Details] | |
| (2017) | Glial Cells in Health and Disease, M Fitzpatrick, I Sweeney, N Boyle, R Magee, S-M Yap, T Hogan, Y Nolan, O Toole, W Hind, E Downer (2017) Assessing toll-like receptor signalling in Multiple Sclerosis both centrally and peripherally. [Poster Presentation], Glial Cells in Health and Disease, Edinburgh UK . [Details] | |
| (2017) | European Neuropsychopharmacology, B.R. Levone, Y.M. Nolan, J.F. Cryan, O.F. O’Leary (2017) Neural progenitor cells from the ventral hippocampus are more sensitive to long-term exposure to corticosterone. [Poster Presentation], European Neuropsychopharmacology, Nice, France . [Details] | |
| (2017) | ECNP workshop for Junior Scientists in Europe, Levone BR, Nolan YM, Cryan JF, O'Leary OF (2017) Region-specific effects of corticosterone on neural progenitors along the dorso-ventral axis of the hippocampus. [Poster Presentation], ECNP workshop for Junior Scientists in Europe, Nice, France . [Details] | |
| (2017) | AD/PDTM 2017, O’Donovan SM, Crowley E, Browne J, O’Sullivan O, O’Leary OF, Timmons S, Nolan YM, O’Toole PW, Clarke DJ, Hyland NP, Joyce SA, Sullivan AM, O’Neill C (2017) The brain ↔gut axis in Parkinson’s disease: defining gut pathology and the impact of exercise in the rAAV-α-synuclein rat model of PD AD/PDTM 2017, the 13th International Conference on Alzheimer's and Parkinson's Diseases and Related Neurological Disorders. [Poster Presentation], AD/PDTM 2017, Vienna,Austria . [Details] | |
| (2016) | College of Medicine and Health, UCC, James D. O'Leary, Cynthia Brouwers, Niek Brosens, Olivia F. O'Leary, John F. Cryan, Aideen Sullivan and Yvonne M. Nolan (2016) Impact of voluntary exercise during adolescence on cognitive performance in a touchscreen operant chamber during adulthood. [Oral Presentation], College of Medicine and Health, UCC, Ireland . [Details] | |
| (2016) | New Horizon's in Medical Research, D. Kozareva, C. Hueston, C. O'Léime, J. Cryan, Y. Nolan (2016) TLX as a protective modulator against IL-1β-induced impairment in hippocampal neurosphere growth. [Poster Presentation], New Horizon's in Medical Research, Ireland . [Details] | |
| (2016) | College of Medicine and Health, UCC, C.M.Hueston, C.S.Ó’Léime, D.A.Kozareva, J.F.Cryan, Y.M.Nolan (2016) Lentiviral overexpression of interleukin-1β in the hippocampus induces neurogenesis-associated cognitive deficits in touchscreen learning paradigms. [Oral Presentation], College of Medicine and Health, UCC, Ireland . [Details] | |
| (2016) | Psychoneuroimmunology Research Society, C.S.OLeime, J.F.Cryan, Y.M.Nolan (2016) IL-1β negatively impacts upon expression of both inflammatory and neurogenesis-associated signalling molecules in hippocampal neural stem cells in vitro. [Poster Presentation], Psychoneuroimmunology Research Society, Brighton, UK . [Details] | |
| (2016) | Society for Neuroscience, C.M.Hueston, C.S.Ó’Léime, D.A.Kozareva, J.F.Cryan, Y.M.Nolan (2016) Lentiviral overexpression of interleukin-1β in the hippocampus induces neurogenesis-associated cognitive deficits in touchscreen location discrimination task. [Poster Presentation], Society for Neuroscience, San Diego USA . [Details] | |
| (2016) | ECNP, C.M.Hueston, C.S.Ó’Léime, D.A.Kozareva, J.F.Cryan, Y.M.Nolan (2016) Lentiviral overexpression of interleukin-1β in the hippocampus induces neurogenesis-associated cognitive deficits in adult male rats. [Poster Presentation], ECNP, Nice, France . [Details] | |
| (2016) | Society for Neuroscience, D. Kozareva, C. Hueston, C. O'Léime, J. Cryan, Y. Nolan (2016) TLX as a protective modulator against IL-1β-induced impairment in hippocampal neurosphere growth. [Poster Presentation], Society for Neuroscience, San Diego USA . [Details] | |
| (2016) | European Neuropsychopharmacology, D. Kozareva, C. Hueston, C. O'Léime, J. Cryan, Y. Nolan (2016) TLX, a regulator of neural stem cell self-renewal, is required for microglial integrity in the adult mouse dentate gyrus. [Poster Presentation], European Neuropsychopharmacology, Nice, France . [Details] | |
| (2016) | European Neuropsychopharmacology, D. Kozareva, C. Hueston, C. O'Léime, J. Cryan, Y. Nolan (2016) TLX, a regulator of neural stem cell self-renewal, is required for microglial integrity in the adult mouse dentate gyrus. [Poster Presentation], European Neuropsychopharmacology, Nice, France . [Details] | |
| (2016) | European Neuropsychopharmacology, D. Kozareva, C. Hueston, C. O'Léime, J. Cryan, Y. Nolan (2016) TLX, a regulator of neural stem cell self-renewal, is required for microglial integrity in the adult mouse dentate gyrus. [Poster Presentation], European Neuropsychopharmacology, Nice, France . [Details] | |
| (2016) | College of Medicine and Health, UCC, Yvonne M. Nolan (2016) The effects of magnesium-rich Aquamin/AquaminMG supplementation in cognitive aging. [Poster Presentation], College of Medicine and Health, UCC, Ireland . [Details] | |
| (2016) | Eurogenesis, James D. O'Leary, Danka A. Kozareva, Cara M. Hueston, Olivia F. O'Leary, John F. Cryan and Yvonne M. Nolan (2016) The nuclear receptor Tlx regulates motor, cognitive and anxiety-related behaviours during adolescence and adulthood. [Poster Presentation], Eurogenesis, Bordeaux, France . [Details] | |
| (2016) | New Horizon's in Medical Research, D. Kozareva, C. Hueston, C. O'Léime, J. Cryan, Y. Nolan (2016) TLX as a protective modulator against IL-1β-induced impairment in hippocampal neurosphere growth. [Poster Presentation], New Horizon's in Medical Research, Ireland . [Details] | |
| (2016) | New Horizon's in Medical Research, D. Kozareva, C. Hueston, C. O'Léime, J. Cryan, Y. Nolan (2016) TLX as a protective modulator against IL-1β-induced impairment in hippocampal neurosphere growth. [Poster Presentation], New Horizon's in Medical Research, Ireland . [Details] | |
| (2016) | European Neuropsychopharmacology, D. Kozareva, C. Hueston, C. O'Léime, J. Cryan, Y. Nolan (2016) TLX, a regulator of neural stem cell self-renewal, is required for microglial integrity in the adult mouse dentate gyrus. [Poster Presentation], European Neuropsychopharmacology, Nice, France . [Details] | |
| (2016) | Eurogenesis, James D. O'Leary, Danka A. Kozareva, Cara M. Hueston, Olivia F. O'Leary, John F. Cryan and Yvonne M. Nolan (2016) The nuclear receptor Tlx regulates motor, cognitive and anxiety-related behaviours during adolescence and adulthood. [Poster Presentation], Eurogenesis, Bordeaux, France . [Details] | |
| (2016) | Eurogenesis, Brunno R. Levone1, Yvonne M. Nolan, John F. Cryan, Olivia F. O’Leary (2016) Neural progenitor cells (NPCs) from the ventral hippocampus are more sensitive to long-term exposure to corticosterone than NPCs from the dorsal or intermediate hippocampus. [Poster Presentation], Eurogenesis, Bordeaux, France . [Details] | |
| (2016) | European Neuropsychopharmacology, C.M. Hueston, C.S. O'Léime, D.A. Kozareva, J.F. Cryan, Y.M. Nolan (2016) Hippocampal overexpression of interleukin-1ß induces neurogenesis-associated cognitive deficits in adult male rats. [Poster Presentation], European Neuropsychopharmacology, Nice, France . [Details] | |
| (2016) | Eurogenesis, James D. O'Leary, Danka A. Kozareva, Cara M. Hueston, Olivia F. O'Leary, John F. Cryan and Yvonne M. Nolan (2016) The nuclear receptor Tlx regulates motor, cognitive and anxiety-related behaviours during adolescence and adulthood. [Poster Presentation], Eurogenesis, Bordeaux, France . [Details] | |
| (2016) | Brain, Behavior, and Immunity, C.S.OLeime, J.F.Cryan, Y.M.Nolan (2016) IL-1β negatively impacts upon expression of both inflammatory and neurogenesis-associated signalling molecules in hippocampal neural stem cells in vitro. [Poster Presentation], Brain, Behavior, and Immunity, Brighton, UK . [Details] | |
| (2016) | New Horizon's in Medical Research, C.M.Hueston, C.S.Ó’Léime, D.A.Kozareva, J.F.Cryan, Y.M.Nolan (2016) Lentiviral overexpression of interleukin-1β in the hippocampus induces neurogenesis-associated cognitive deficits in touchscreen learning paradigms. [Oral Presentation], New Horizon's in Medical Research, Ireland . [Details] | |
| (2016) | Eurogenesis, C.M.Hueston, C.S.Ó’Léime, D.A.Kozareva, J.F.Cryan, Y.M.Nolan (2016) Lentiviral overexpression of interleukin-1β in the hippocampus induces neurogenesis-associated cognitive deficits in adult male rats. [Poster Presentation], Eurogenesis, Bordeaux, France . [Details] | |
| (2016) | Society for Neuroscience, James D. O'Leary, Cynthia Brouwers, Niek Brosens, Olivia F. O'Leary, John F. Cryan, Aideen M. Sullivan and Yvonne M. Nolan (2016) Impact of voluntary exercise during adolescence on cognitive performance in a touchscreen operant chamber during adulthood. [Poster Presentation], Society for Neuroscience, San Diego . [Details] | |
| (2016) | College of Medicine and Health, UCC, "Danka A. Kozareva, Cara M. Hueston, Ciarán S. Ó Léime, Olivia F. O’Leary, John F. Cryan, Yvonne M. Nolan " (2016) Exercise and social interaction influence hippocampal neurogenesis in adolescent mice. [Poster Presentation], College of Medicine and Health, UCC, Ireland . [Details] | |
| (2016) | Eurogenesis, James D. O'Leary, Danka A. Kozareva, Cara M. Hueston, Olivia F. O'Leary, John F. Cryan and Yvonne M. Nolan (2016) The nuclear receptor Tlx regulates motor, cognitive and anxiety-related behaviours during adolescence and adulthood. [Poster Presentation], Eurogenesis, Bordeaux, France . [Details] | |
| (2016) | Brain, Behavior, and Immunity, C.M.Hueston, C.S.Ó’Léime, D.A.Kozareva, J.F.Cryan, Y.M.Nolan (2016) Lentiviral overexpression of interleukin-1β in the hippocampus induces neurogenesis-associated cognitive deficits in adult male Sprague–Dawley rats. [Poster Presentation], Brain, Behavior, and Immunity, UK . [Details] | |
| (2016) | ECNP, D. Kozareva, C. Hueston, C. O'Léime, J. Cryan, Y. Nolan (2016) TLX, a regulator of neural stem cell self-renewal, is required for microglial integrity in the adult rodent dentate gyrus. [Poster Presentation], ECNP, Nice, France . [Details] | |
| (2016) | Eurogenesis, James D. O'Leary, Danka A. Kozareva, Cara M. Hueston, Olivia F. O'Leary, John F. Cryan and Yvonne M. Nolan (2016) The nuclear receptor Tlx regulates motor, cognitive and anxiety-related behaviours during adolescence and adulthood. [Poster Presentation], Eurogenesis, Bordeaux, France . [Details] | |
| (2016) | Eurogenesis, Brunno R. Levone1, Yvonne M. Nolan, John F. Cryan, Olivia F. O’Leary (2016) Neural progenitor cells (NPCs) from the ventral hippocampus are more sensitive to long-term exposure to corticosterone than NPCs from the dorsal or intermediate hippocampus IL-1β negatively impacts upon expression of both inflammatory and neurogenesis-associated signalling molecules in hippocampal neural stem cells in vitro. [Poster Presentation], Eurogenesis, Bordeaux, France . [Details] | |
| (2016) | Eurogenesis, James D. O'Leary, Danka A. Kozareva, Cara M. Hueston, Olivia F. O'Leary, John F. Cryan and Yvonne M. Nolan (2016) The nuclear receptor Tlx regulates motor, cognitive and anxiety-related behaviours during adolescence and adulthood. [Poster Presentation], Eurogenesis, Bordeaux, France . [Details] | |
| (2016) | Brain, Behavior, and Immunity, C.M.Hueston, C.S.Ó’Léime, D.A.Kozareva, J.F.Cryan, Y.M.Nolan (2016) Lentiviral overexpression of interleukin-1β in the hippocampus induces neurogenesis-associated cognitive deficits in adult male Sprague–Dawley rats. [Poster Presentation], Brain, Behavior, and Immunity, UK . [Details] | |
| (2016) | New Horizon's in Medical Research, James D. O'Leary, Cynthia Brouwers, Niek Brosens, Olivia F. O'Leary, John F. Cryan, Aideen Sullivan and Yvonne M. Nolan (2016) Impact of voluntary exercise during adolescence on cognitive performance in a touchscreen operant chamber during adulthood. [Invited Oral Presentation], New Horizon's in Medical Research, Ireland . [Details] | |
| (2015) | Society for Neuroscience, Danka Kozareva, Y.M Nolan (2015) TLX, a regulator of neural stem cell self-renewal is required for microglial integrity in the adult mouse dentate gyrus. [Poster Presentation], Society for Neuroscience, United States of America . [Details] | |
| (2015) | NECTAR, Erin Dolan, Y.M Nolan (2015) Characterisation of cognitive deficits in an a-synuclein model of Parkinson's disease. [Poster Presentation], NECTAR, Sweden . [Details] | |
| (2015) | College of Medicine and Health, UCC, Erin Dolan, Y.M Nolan (2015) Characterisation of cognitive dysfunction in an α-synuclein rodent model of Parkinson’s disease. [Poster Presentation], College of Medicine and Health, UCC, Ireland . [Details] | |
| (2015) | College of Medicine and Health, UCC, C.S.OLeime, J.F.Cryan, Y.M.Nolan (2015) IL-1beta negatively impacts upon expression of both inflammatory and neurogenesis-associated signalling molecules in hippocampal neural stem cells in vitro. [Poster Presentation], College of Medicine and Health, UCC, Ireland . [Details] | |
| (2015) | European Neuropsychopharmacology, M. Pusceddu, Y.M. Nolan, H. Green, P. Kelly, J. Cryan, T. Dinan (2015) Docosahexaenoic acid as a novel strategy for stress-related disorders: reversal of corticosterone-induced changes in cortical neurons. [Poster Presentation], European Neuropsychopharmacology, Netherlands . [Details] | |
| (2015) | CINP, Yvonne M. Nolan (2015) Neuroinflammation and Hippocampal Neurogenesis. [Oral Presentation], CINP, Ireland . [Details] | |
| (2015) | College of Medicine and Health, UCC, James D. O'Leary, Danka A. Kozareva, Cara M. Hueston, Olivia F. O'Leary, John F. Cryan, Yvonne M. Nolan (2015) The nuclear receptor TLX regulates motor, cognitive and anxiety-related behaviours during adolescence and adulthood. [Poster Presentation], College of Medicine and Health, UCC, Ireland . [Details] | |
| (2015) | European Neuropsychopharmacology, Yvonne M. Nolan (2015) Inflammation and Adult Hippocampal Neurogenesis. [Oral Presentation], European Neuropsychopharmacology, Netherlands . [Details] | |
| (2015) | Society for Neuroscience, Erin Dolan, Y.M Nolan (2015) Characterisation of cogniive deficits in an a-synuclein model of Parkinson's disease. [Poster Presentation], Society for Neuroscience, United States of America . [Details] | |
| (2015) | Neuroscience Ireland, C.M.Hueston, C.S.Ó’Léime, D.A.Kozareva, J.F.Cryan, Y.M.Nolan (2015) Lentiviral overexpression of interleukin-1beta in the hippocampus induces neurogenesis-associated cognitive deficits in adult male rats. [Invited Oral Presentation], Neuroscience Ireland, Ireland . [Details] | |
| (2015) | CINP, Danka Kozareva, Y.M Nolan (2015) TLX, a regulator of neural stem cell self-renewal is required for microglial integrity in the adult mouse dentate gyrus. [Poster Presentation], CINP, Ireland . [Details] | |
| (2015) | New Horizon's in Medical Research, C.M.Hueston, C.S.Ó’Léime, D.A.Kozareva, J.F.Cryan, Y.M.Nolan (2015) Lentiviral overexpression of interleukin-1β in the hippocampus induces neurogenesis-associated cognitive deficits in adult male rats. [Poster Presentation], New Horizon's in Medical Research, Ireland . [Details] | |
| (2015) | ICVS Neuroconferences workshop, Brunno Rocha Levone, Ciaran O’Leime, Yvonne M. Nolan, John F. Cryan, Olivia F. O’Leary (2015) The effects of corticosterone on neuroprogenitor cells dervived from specific regions of the longitudinal axis of the hippocampus. [Poster Presentation], ICVS Neuroconferences workshop, Braga, Portugal . [Details] | |
| (2015) | College of Medicine and Health, UCC, Levone BR, O’Leime C, Nolan YM, Cryan JF, O’Leary (2015) Corticosterone differentially affects neural progenitor cells derived from specific areas of the longitudinal axis of the hippocampus. [Poster Presentation], College of Medicine and Health, UCC, Ireland . [Details] | |
| (2015) | European Behavioural Pharmacology Society, James D. O'Leary, Danka A. Kozareva, Cara M. Hueston, Olivia F. O'Leary, John F. Cryan and Yvonne M. Nolan (2015) The nuclear receptor TLX regulates cognitive processes during adolescence and adulthood. [Poster Presentation], European Behavioural Pharmacology Society, Verona, Italy . [Details] | |
| (2015) | College of Medicine and Health, UCC, Danka Kozareva, Y.M Nolan (2015) TLX, a regulator of neural stem cell self-renewal, is required for microglial integrity in the adult mouse dentate gyrus. [Poster Presentation], College of Medicine and Health, UCC, Ireland . [Details] | |
| (2015) | ECNP, Yvonne Nolan (2015) Inflammation and Adult Hippocampal Neurogenesis. [Oral Presentation], ECNP, Netherlands . [Details] | |
| (2014) | Brain, Behavior, and Immunity, C.M.Hueston, B.R.Amels, J.D.O’Leary, S.M.Ryan, J.F.Cryan, Y.M.Nolan (2014) Lentiviral over-expression of interleukin-1 beta in the hippocampus induces cognitive deficits: Selective reversal by voluntary exercise throughout adolescence. [Poster Presentation], Brain, Behavior, and Immunity, Brighton, UK . [Details] | |
| (2005) | Royal Irish Academy of Medicine, Harris, D.M., Fisher, A., Harkin, A.J., Bolton,A.E., Sullivan, A.M., Nolan, Y.M. (2005) Novel phospholipid-based drug formulation prevents degeneration of dopaminergic neurons from substantia nigra in a rat model of Parkinson’s disease. [Poster Presentation], Royal Irish Academy of Medicine, Dublin, Ireland , 05-JAN-05 - 06-JAN-05. [Details] | |
| (2005) | 16th International Conference on Parkinson's Disease, Harris, D.M., Fisher, A., Mandel, A., Bolton, A.E., Sullivan, A.M., Nolan, Y. (2005) 6-hydroxydopamine-induced degeneration of rat nigral dopaminergic neurons and microglial activation is reduced by treatment with a novel phospholipid-based drug formulation. [Poster Presentation], 16th International Conference on Parkinson's Disease, Berlin, Germany , 05-JUN-05 - 09-JUN-05. [Details] | |
| (2005) | Royal Irish Academy of Medicine, Fitzgerald, P., Harris, D.M., Crotty, S., Fisher, A., Mandel, A., Bolton, A.E., Sullivan, A.M., Nolan, Y.M. (2005) 6-hydroxydopamine-induced degeneration of rat nigral dopaminergic neurons and microglial activation is reduced by treatment with a novel phospholipid-based drug formulation. [Poster Presentation], Royal Irish Academy of Medicine, Dublin, Ireland , 05-JUN-05 - 06-JUN-05. [Details] |
Committees
| Committee | Function | From / To | |
|---|---|---|---|
| Steering Committee: Postgraduate Research Administration Improvement Project | Vice Dean of Graduate Studies, College of Medicine and Health | 2021 / | |
| College of Medicine and Health Executive Committee | Vice Dean of Graduate Studies, College of Medicine and Health | 2021 / | |
| College Council, College of Medicine and Health | Vice Dean of Graduate Studies, College of Medicine and Health | 2021 / | |
| Academic Council Graduate Studies Committee | Vice Dean of Graduate Studies, College of Medicine and Health | 2021 / | |
| College of Medicine and Health Graduate Studies Committee | Chair | 2021 / | |
| Irish Laboratory Awards Judging Panel | Member | 2019 / | |
| Academic Council | Member | 2019 / | |
| Horizon2020 Marie Sklodowak-Curie COFUND | Grant Reviewer (2019-present) | 2019 / | |
| French National Research Agency | Grant Reviewer (2018-present) | 2018 / | |
| Dementia Research and Innovation Programme, Memorabel, The Netherlands | Grant Reviewer (2018-present) | 2018 / | |
| Biotechnology and Biological Sciences Research Council (BBSRC) | Grant Reviewer (2018-present) | 2018 / | |
| Dementia and Neurodegeneration Network Ireland (DNNI) | Member | 2017 / | |
| Alzheimer's Society | Grant Reviewer (2017-present) | 2017 / | |
| Independent Advisory Board for Wellcome/HRB Irish Clinical Academic Training (ICAT) programme | Member | 2016 / | |
| College of SEFS Board of Studies for CK402 degree | Committee member | 2016 / 2020 | |
| College of SEFS Academic Programmes and Curriculum Development Committee | Committee member | 2016 / 2020 | |
| United States-Israel Binational Science Foundation, Grant Reviewer 2016 - present | Grant Reviewer | 2016 / | |
| Research and Postgraduate Affairs Committee, School of Medicine | Committee member | 2016 / | |
| Co-organiser of Symposium on ‘The Hippocampus in Health and Disease’ with guest speaker Nobel Laureate John O’Keefe | Co-organiser | 2015 / 2015 | |
| Continuing Professional Development Steering Group in College of Medicine & Health | Committee member | 2015 / | |
| Italian Ministry for Health, General Directorate for Scientific Research and Health Innovation, Grant Reviewer 2015 - present | Grant Reviewer | 2015 / | |
| Medical Research Council UK; Neurosciences and Mental Health Board. Grant Reviewer 2013 - present | Grant Reviewer | 2013 / | |
| Fonds National de la Recherche Luxembourg, CORE research programme. Grant Reviewer 2013 - present | Grant Reviewer | 2013 / | |
| Neuroscience Ireland Conference Organising Committee | Committee member | 2013 / 2013 | |
| Netherlands Organisation for Scientific Research: Innovational Research Incentives Scheme. Grant Reviewer 2013 - present | Grant Reviewer | 2012 / | |
| Expert reviewer for the European Commission’s FP7-HEALTH evaluation of research proposals submitted under the area "Brain and Related Diseases" 2010 - 2011 | Expert Evaluator | 2010 / 2011 | |
| Parkinson’s Disease Society, UK. Grant Reviewer 2010 - present | Grant Reviewer | 2010 / | |
| Neuroscience Ireland Conference Organising Committee. | Committee member | 2006 / 2006 | |
| Canadian Council on animal care | Reviewer | 2004 / 2006 | |
| Departmental Representative on the School of Clinical Therapies School Board | To co-ordinate the resources necessary to deliver the educational programmes of the professions and to promote related postgraduate research. | 2003 / 2016 | |
| Member of the School of Medicine Postgraduate and Continuing Education Committee | To implement policies and procedures for postgraduate and lifelong learning programmes offered in the School, ensure high standards in supervision and progress, develop and review curricula for new postgraduate programmes. | 2012 / 2016 | |
| Expert Member of the Europa Research Participant Portal for the European Commission | Grant evaluator for topic 'Understanding the role of neuroinflammation in neurodegenerative diseases' | 2010 / 2016 | |
| Chair of Anatomy Department Postgradute Studies Committee | Annual assessment of progress of MSc, MD and PhD students | 2007 / 2013 | |
| College of Medicine and Health representative on Cork NeuroscienceCommittee | To promote collaborative research between clinical and basic neuroscience researchers. | 2006 / 2010 | |
| Neuroscience thematic committee for PRTLI-funded PhD programme in Trinity College Dublin | External assessor on the Neuroscience thematic committee for PRTLI-funded PhD programme in Molecular and Cellular Mechanisms underlying Inflammatory processes | 2012 / 2016 | |
| Committee Member of Animal Experimentation Ethics Committee, UCC | To ensure on both moral and scientific grounds, that the use of animals is carefully evaluated ensuring scientific and/or educational validity, usefulness and relevance; To comply with the legislation in relation to laboratory animal research in UCC. | 2012 / 2016 | |
| Departmental Representative on the School of Medicine Curriculum Committee | To define the objectives, structure and outline for each undergraduate programme offered in the School, as well as document, approve and review processes and performances. This year I represented the curriculum committee and the School of Medicine, UCC on the Irish Universities and Medical Schools Consortium (IUMC) trip to Malaysia to interview prospective candidates to study Medicine in Ireland (Jan 2013). | 2012 / 2014 | |
| Chair of Departmental Curriculum Committee | Organisation of regular (1-2/term) departmental committee meetings to review, update and improve current teaching, examining and curriculum input into the nine programmes that the department currently contributes to. | 2012 / 2014 | |
| Member of the School of Clinical Therapies Student Affairs Committee | To maintain an active awareness of issues relating to student education, student personal and professional development and to respond to student concerns. | 2004 / 2010 | |
| Royal Academy of Medicine Ireland, Biomedical Section: Council member | Council member | 2005 / 2011 | |
| Neuroscience Ireland Council member | Council Member | 2006 / 2012 |
Employment
| Employer | Position | From / To | |
|---|---|---|---|
| University College Cork | Senior Lecturer | 01-NOV-11 / | |
| University College Cork | Lecturer | 17-NOV-03 / 28-OCT-11 | |
| Trinity College Dublin | Postdoctoral Research Fellow | 01-JAN-03 / 16-NOV-03 | |
| Trinity College Dublin | Teaching Assistant | 01-OCT-02 / 30-JUN-03 | |
| St. James' Hospital, Trinity College Dublin | Tutor in Biological Sciences | 01-OCT-01 / 30-JUN-02 | |
| Vasogen Ireland Limited | Postdoctoral researcher | 01-SEP-00 / 31-DEC-02 | |
| Quintiles Ireland Ltd | Clinical Data Coordinator | 01-OCT-99 / 31-AUG-00 |
Education
| Year | Institution | Qualification | Subject | |
|---|---|---|---|---|
| 2005 | University College Cork | Postgraduate Certificate in Teaching and Learning in Higher Ed. | Teaching and Learning | |
| 1999 | NUI Galway | PhD | Pharmacology | |
| 1996 | NUI Galway | BSc | Biochemistry |
Languages
| Language | Reading | Writing | Speaking | |
|---|---|---|---|---|
| French | Functional | Functional | Functional | |
| Irish | Functional | Functional | Functional | |
| English | Fluent | Fluent | Fluent |
Consultancy
| Client | Description | |
|---|---|---|
| Vasogen Ireland Ltd |
Journal Activities
| Journal | Role | To / From | |
|---|---|---|---|
| Neuronal Signaling | Referee | - | |
| The European Journal Of Neuroscience | Referee | - | |
| Physiology And Behaviour | Referee | - | |
| Psychoneuroendocrinology | Referee | - | |
| Nutritional Neuroscience | Referee | - | |
| Neuropeptides | Referee | - | |
| Neurobiology Of Stress | Referee | - | |
| Neurobiology Of Aging | Referee | - | |
| Nature Communications | Referee | - | |
| Molecular And Cellular Neuroscience | Referee | - | |
| Irish Journal Of Medical Science (1971 -) | Referee | - | |
| International Journal Of Neuropsychopharmacology | Referee | - | |
| Hormones And Behavior | Referee | - | |
| Frontiers In Psychiatry | Referee | - | |
| Frontiers In Neuroscience | Referee | - | |
| Frontiers In Neurology | Referee | - | |
| Frontiers In Human Neuroscience | Referee | - | |
| Faseb Journal | Referee | - | |
| European Journal Of Nutrition | Referee | - | |
| Scientific Reports | Referee | - | |
| Neuroscience Letters | Referee | - | |
| Journal Of Pharmacology And Experimental Therapeutics | Referee | - | |
| Journal Of Neuroinflammation | Referee | - | |
| Journal Of Cell Science | Referee | - | |
| Cellular And Molecular Life Sciences | Referee | - | |
| Biotechnology And Bioengineering | Referee | - | |
| Journal Of Biological Chemistry | Referee | - | |
| Journal Of The Neurological Sciences | Referee | - | |
| British Journal Of Pharmacology | Referee | - | |
| Journal Of Anatomy | Referee | - | |
| Brain Research | Referee | - | |
| Neurotoxicity Research | Referee | - | |
| Neuropharmacology | Referee | - | |
| Inflammation Research | Referee | - | |
| Frontiers In Neurodegenerative Disease | Member of Editorial Board | - | |
| Phytotherapy Research | Referee | - | |
| Brain Behav Immun | Member of Editorial Board | - | |
| Experimental Neurology | Referee | - | |
| Behavioral Brain Research | Referee | - | |
| Plos One | Referee | - | |
| Molecular And Cellular Biology | Referee | - | |
| Molecular Neurobiology | Referee | - | |
| Journal Of Neuroscience Research | Referee | - | |
| Parkinson’S Disease | Guest Editor | - | |
| Frontiers In Aging Neuroscience | Referee | - | |
| Cns Neuroscience And Therapeutics | Referee | - | |
| Journal Of Molecular Cell Biology | Referee | - | |
| Biotechnology And Bioengineering | Referee | - | |
| Stem Cell Research And Therapy | Referee | - |
Outreach Activities
| Description | |
|---|---|
Career Development for Postgraduate students and Postdoctoral Fellows:
Contribution to Open Days and School Liaison activities:
| |
Contribution to Public Awareness of Neuroscience:
|
Other Activities
| Description | |
|---|---|
Recent Measures of Esteem
Membership of national and international peer review and research funding bodies
Membership of external advisory bodies
Recent Invited presentations
Conference organisation
Mentoring
Relevant Short Professional Courses:
|
Teaching Activities
Teaching Interests
Leadership in Neuroscience: Dr. Nolan was Director of the BSc Neuroscience (2015-2020) and co-ordinates (currently/past five years) seven neuroscience modules (AN2020; AN3001; AN4011; AN4013; AN4014; AN4015; AN6031).She established a staff-student liaison committee, peer mentoring, career advisory sessions, Student Declaration and Code of Conduct, Work placement module, alumni talks, information video, Twitter handle and programme email address for prospective students. She also co-ordinated the Intercalated BSc in Neuroscience for Medical students.Leadership in Anatomy: Dr. Nolan has developed curriculum, taught and assessed Anatomy to students in Occupational, Speech and Language Therapy, Medicine, Dentistry, Pharmacy, and to postgraduate students in Anatomy, Osteoarchaeology and Audiology since her appointment in 2003. She was Anatomy liaison for School of Clinical Therapies (2004–2016). She has represented the department at School and Exam Boards and in the accreditation and re-accreditation of both Occupational Therapy and Speech and Language Therapy programmes since 2006. She co-ordinates/previously co-ordinated six anatomy modules (AN1060; AN1061; AN1074; AN3005; AN3006; AN6001).
Research-led teaching: Dr. Nolan draws on her expertise in cognitive function, inflammation and lifestyle factors influencing the brain in her teaching. She leads an active research group in Neuroscience and impart her expertise in three research-based modules (AN4011, AN4013, AN4014) which she coordinates. She has supervised 6 taught MSc dissertation students, >50 undergraduate projects, >60 library projects and seven ERASMUS projects (Grenoble, Beijing, Amsterdam, Toulouse).
Teaching Qualification:
- 2005: Postgraduate Certificate in Teaching and Learning in Higher Education
- 2019: National Forum for the Enhancement of Teaching and Learning in Higher Education - Harnessing the power of adolescent brain and behaviour for enhanced learning, wellbeing and student success. €30,000
- 2019: National Forum for the Enhancement of Teaching and Learning in Higher Education - Connecting the DOTS - Developmental Opportunities in Transitions for Students. €1000
- 2007: National Academy award for the Integration of Research and Teaching and Learning (NAIRTL) for a submission entitled " Research Methodology in Neuroscience and Biomedical Science"
Chair of BSc Neuroscience curriculum committee (2016-present)
College of SEFS Academic Programmes and Curriculum Development Committee (2016 - 2020)
College of SEFS Board of Studies for Biological and Chemical Science degree (2016 - 2020)
School of Medicine Research and Postgraduate Affairs Committee, UCC (2012–present)
Continuing Professional Development Steering Group, College of Medicine & Health (2015-2018)
School of Medicine Curriculum Committee (2012–2014)
Departmental Representative on the Clinical Therapies School Board (2003-2017)
Chair of Departmental Anatomy Curriculum Committee (2012-2014)
Chair of Departmental Graduate Studies Committee (2008-2013)
Recent Postgraduates
| Graduation Year | Student Name | Institution | Degree Type | Thesis Title | |
|---|---|---|---|---|---|
| 2017 | Ashley Murphy | University College Cork | MSc | The differential effect of exercise during adolescence and adulthood on the development of new neurons in the hippocampus | |
| 2019 | Lauren Pawley | University College Cork | MSc | The impact of chronic neuroinflammation on adult and adolescent hippocampal neurogenesis and on the stressed brain. | |
| 2017 | James O'Leary | University College Cork | PHD | Adolescence as a Vulnerable Period for the Effects of Intrinsic & Extrinsic Regulators of Neurogenesis on Cognitive Behaviour. | |
| 2018 | Danka Kozareva | University College Cork | PHD | Novel insights into the role of hippocampal TLX in neurogenesis, neuroinflammation and behaviour in adolescence and adulthood. | |
| 2017 | Erin Crowley | University College Cork | PHD | Non-motor symptoms in the AAV-α-synuclein rat model of Parkinson’s disease: exercise as a therapeutic intervention | |
| 2012 | Holly Green | University College Cork | PHD | Deciphering the role of Wnt signalling on inflammation-induced changes in hippocampal neurogenesis. | |
| 2017 | Ciaran O'Leime | University College Cork | PHD | Investigating the regulatory role of the nuclear receptor TLX in IL-1β-induced changes in hippocampal neurogenesis. | |
| 2019 | Catherine Fives | University College Cork | MSc | Motivation and Learning Methods of Anatomy: Associations with Mental Well-being in a cohort of first year Speech and Language Therapy Students. | |
| 2013 | Sinead Ryan | University College Cork | PHD | The role of the IL-1 type 1 receptor in the life, death and differentiation of adult hippocampal neural precursor cells. | |
| 2008 | Caitriona Long | University College Cork | PHD | The role of inflammation and p38 in 6-hydroxydopamine-induced dopaminergic neuronal death - implications for Parkinson's disease. | |
| 2010 | Aoife Keohane | PHD | Effect of pro-inflammatory cytokines on the fate of embryonic hippocampal neural precursor cells. | ||
| 2011 | Eimear Treacy | University College Cork | MSc Health Sciences | The effects of interleukin-1beta on the growth and differentiation of embryonic rat hippocampal neural precursor cells. | |
| 2013 | Louise Collins | University College Cork | PHD | The role of MKP1 in the survival and functional integration of dopaminergic neurons. | |
| 2010 | Tessa van der Maaden | European University Institute | MSc | The effects of the pro-inflammatory cytokine IL-1β on neurogenesis in the adult rat hippocampus | |
| 2012 | Ian OBrien | University College Cork | MSc | Transcription factor regulation of dopaminergic neural stem call fate in an inflammatory environment | |
| 2008 | Edel McGuane | University College Cork | MSc | The role of a novel glutamate receptor agonist in promoting the survival of hippocampal neural precursor cells |
Current Postgraduate Students
| Student | Degree Type | |
|---|---|---|
| O Shea Jenna Anne | Doctoral Degree | |
| Caruso Maria Giovanna | Doctoral Degree | |
| Allard Dohm-Hansen Dee-Jay Heinrich Sebastian | Doctoral Degree |
Research Information
Internal Collaborators
| Name | Institute | Country | |
|---|---|---|---|
| Dr. Jane Englsih | University College Cork | ||
| Professor Paul Lucassen | University of Amsterdam | HOLLAND | |
| Dr. Olivia O'Leary | University College Cork | IRELAND | |
| Professor Cora O'Neill | University College Cork | ||
| Dr. Jason Chan | University College Cork | ||
| Dr. Samantha Dockray | University College Cork | ||
| Dr. Eithne Hunt | University College Cork | ||
| Dr. Annalisa Setti | University College Cork | ||
| Prof. John Cryan | University College Cork | IRELAND |
External Collaborators
| Name | Organisation / Institute | Country | |
|---|---|---|---|
| Dr. Sandrine Thuret | King's College London | UNITED KINGDOM | |
| Prof. Marina Lynch | Trinity College Dublin | IRELAND | |
| Dr. Annamaria Cattaneo | IRCCS Fatebenefratelli Institute | ITALY | |
| Dr. Denise O'Gorman | Marigot Ireland Limited | IRELAND | |
| Dr. Andrew Harkin | Trinity College Dublin | IRELAND | |
| Prof. Elizabeth Simpson | University of British Columbia | CANADA | |
| Prof. Thomas Connor | Trinity College Dublin | IRELAND | |
| Prof. Peter Dockery | National University of Ireland, Galway | IRELAND |