Research Profile

Roisin Kelly

Biography

 Dr Roisin Kelly-Laubscher is a Lecturer in Pharmacology & Therapeutics. She received a BSc (Hons) in Physiology, UCC in 2003 and continued in the Department of Physiology with her doctoral studies in the laboratory of Dr HM Snow. He PhD research focused on arterial hemodynamics, the arterial endothelium and the endothelial glycocalyx. After finishing my PhD in 2006, she moved to South Africa to take up a Postdoctoral position at the Hatter Institute for Cardiovascular Research at the University of Cape Town (UCT). She spent 3 years working at the Hatter Institute under the guidance of Prof. Lionel H Opie and Ass. Prof. Sandrine Lecour. From August 2009- Feb 2018, she was appointed as a lecturer (and later promoted to senior lecturer) at UCT. While there her research focused on myocardial infarction, ischemia reperfusion injury and cardioprotection, and more recently  the role of the endothelial glycocalyx in cardioprotection. 

Publications

Peer Reviewed Journals

 YearPublication
(2020)'The effect of sphingosine-1-phosphate on the endothelial glycocalyx during ischemia-reperfusion injury in the isolated rat heart'
Araibi, H;van der Merwe, E;Gwanyanya, A;Kelly-Laubscher, R (2020) 'The effect of sphingosine-1-phosphate on the endothelial glycocalyx during ischemia-reperfusion injury in the isolated rat heart'. Microcirculation, [DOI] [Details]
(2017)'Beneficial Effects of Magnesium Treatment on Heart Rate Variability and Cardiac Ventricular Function in Diabetic Rats'
Amoni M and Kelly-Laubscher R and Blackhurst D and Gwanyanya A (2017) 'Beneficial Effects of Magnesium Treatment on Heart Rate Variability and Cardiac Ventricular Function in Diabetic Rats'. Journal Of Cardiovascular Pharmacology And Therapeutics, [DOI] [Details]
(2017)'Supporting the teaching of the visual literacies in the earth and life sciences in higher education'
Moragh Paxton and Vera Frith and Roisin Kelly-Laubscher and Natashia Muna and Mathilde van der Merwe (2017) 'Supporting the teaching of the visual literacies in the earth and life sciences in higher education'. Higher Education Research and Development, :1-16   [DOI] [Details]
(2017)'Using the research article as a model for teaching laboratory report writing provides opportunities for development of genre awareness and adoption of new literacy practices'
Roisin F. Kelly-Laubscher and Natashia Muna and Mathilde van der Merwe (2017) 'Using the research article as a model for teaching laboratory report writing provides opportunities for development of genre awareness and adoption of new literacy practices'. English for Specific Purposes, 48 :1-16   [DOI] [Details]
(2016)'Differences in Curriculum Structure between High School and University Biology: The Implications for Epistemological Access'
Roisin Kelly-Laubscher (2016) 'Differences in Curriculum Structure between High School and University Biology: The Implications for Epistemological Access'. Journal of Biological Education,   [DOI] [Details]
(2016)'First-year medical students\textquotesingle naïve beliefs about respiratory physiology'
Elmi Badenhorst and Silvia Mamede and Amaal Abrahams and Kishor Bugarith and Jacqui Friedling and Geney Gunston and Roisin Kelly-Laubscher and Henk G. Schmidt (2016) 'First-year medical students\textquotesingle naïve beliefs about respiratory physiology'. Advances in Physiology Education, 40 (3):342-348   [DOI] [Details]
(2011)'The effect of arterial wall shear stress on the incremental elasticity of a conduit artery'
Roisin Kelly and Henry Michael Snow (2011) 'The effect of arterial wall shear stress on the incremental elasticity of a conduit artery'. Acta Physiologica,   [Details]
(2017)'Cardioprotective and Anti-arrhythmic Effects of Magnesium Pretreatment Against Ischaemia/Reperfusion Injury in Isoprenaline-Induced Hypertrophic Rat Heart'
Amoni M and Kelly-Laubscher R and Petersen M and Gwanyanya A (2017) 'Cardioprotective and Anti-arrhythmic Effects of Magnesium Pretreatment Against Ischaemia/Reperfusion Injury in Isoprenaline-Induced Hypertrophic Rat Heart'. Cardiovascular Toxicology, [DOI] [Details]
(2015)'Lack of cardioprotection by single-dose magnesium prophylaxis on isoprenaline-induced myocardial infarction in adult Wistar rats: cardiovascular topics'
Garson, Christie and Kelly-Laubscher, Roisin and Blackhurst, Dee and Gwanyanya, Asfree (2015) 'Lack of cardioprotection by single-dose magnesium prophylaxis on isoprenaline-induced myocardial infarction in adult Wistar rats: cardiovascular topics'. Cardiovascular Journal of Africa, 26 (6):242-249 [Details]
(2015)'Cellular targets of inhalational anaesthetic-and opioid receptor agonist-induced cardioprotection'
Gwanyanya, Asfree and Kelly-Laubscher, Roisin (2015) 'Cellular targets of inhalational anaesthetic-and opioid receptor agonist-induced cardioprotection'. Journal of African Association of Physiological Sciences, 3 (1):1-8 [Details]
(2014)'Cardiac preconditioning with sphingosine-1-phosphate requires activation of signal transducer and activator of transcription-3: cardiovascular topic'
Kelly-Laubscher, Roisin F and King, Jonathan C and Hacking, Damian and Somers, Sarin and Hastie, Samantha and Stewart, Tessa and Imamdin, Aqeela and Maarman, Gerald and Pedretti, Sarah and Lecour, Sandrine (2014) 'Cardiac preconditioning with sphingosine-1-phosphate requires activation of signal transducer and activator of transcription-3: cardiovascular topic'. Cardiovascular Journal of Africa, 25 (3):118-123 [Details]
(2013)'Detrimental effects of acute hyperglycaemia on the rat heart'
Mapanga, Rudo F and Joseph, Danzil and Symington, Burger and Garson, K-L and Kimar, Charlene and Kelly-Laubscher, Roisin and Essop, M Faadiel (2013) 'Detrimental effects of acute hyperglycaemia on the rat heart'. Acta Physiologica, 210 (3):546-564 [Details]
(2012)'Oleanolic acid: a novel cardioprotective agent that blunts hyperglycemia-induced contractile dysfunction'
Mapanga, Rudo F and Rajamani, Uthra and Dlamini, Nonkululeko and Zungu-Edmondson, Makhosazane and Kelly-Laubscher, Roisin and Shafiullah, Mohammed and Wahab, Athiq and Hasan, Mohamed Y and Fahim, Mohamed A and Rondeau, Philippe and others (2012) 'Oleanolic acid: a novel cardioprotective agent that blunts hyperglycemia-induced contractile dysfunction'. Plos One, 7 (10) [Details]
(2012)'The effects of acute ethanolamine administration on isoprenaline-induced myocardial infarction in adult Wistar rats'
Garson, Christie and Gwanyanya, Asfree and Bugarith, Kishor and Kelly-Laubscher, Roisin (2012) 'The effects of acute ethanolamine administration on isoprenaline-induced myocardial infarction in adult Wistar rats'. South African Heart Journal, 9 (3) [Details]
(2010)'Ethanolamine is a novel STAT-3 dependent cardioprotective agent'
Kelly, Roisin F and Lamont, Kim T and Somers, Sarin and Hacking, Damian and Lacerda, Lydia and Thomas, Paul and Opie, Lionel H and Lecour, Sandrine (2010) 'Ethanolamine is a novel STAT-3 dependent cardioprotective agent'. Basic Research in Cardiology, 105 (6):763-770 [Details]
(2008)'Dilatation In The Femoral Vascular Bed Does Not Cause Retrograde Relaxation of The Iliac Artery In The Anaesthetized Pig'
Markos, F, Ruane-O'Hora, T, Snow, HM, Kelly, R, Wainwright, C, Skene, K, Drake-Holland, AJ, Noble, MIM; (2008) 'Dilatation In The Femoral Vascular Bed Does Not Cause Retrograde Relaxation of The Iliac Artery In The Anaesthetized Pig'. Acta Physiologica, 194 (3):207-213 [DOI] [Details]
(2007)'Characteristics of the response of the iliac artery to wall shear stress in the anaesthetized pig'
Kelly, RF and Snow, HM (2007) 'Characteristics of the response of the iliac artery to wall shear stress in the anaesthetized pig'. The Journal of Physiology, 582 (2):731-743 [Details]
(2006)'Differential inhibition by hyperglycaemia of shear stress- but not acetylcholine-mediated dilatation in the iliac artery of the anaesthetized pig'
Kelly, R,Ruane-O'Hora, T,Noble, MIM,Drake-Holland, AJ,Snow, HM; (2006) 'Differential inhibition by hyperglycaemia of shear stress- but not acetylcholine-mediated dilatation in the iliac artery of the anaesthetized pig'. Journal of Physiology-London, 573 :133-145 [DOI] [Details]

Conference Publications

 YearPublication
(2008)International Society for Heart Research, Athens, 2008
Kelly, Roisin and King, Jonathan and Lecour, Sandrine (2008) Sphingosine-1-phosphate induced cardioprotection is mediated by STAT-3 International Society for Heart Research, Athens, 2008 , pp.740-741 [Details]
(2007)Royal Academy of Medicine in Ireland, Summer Meeting, Cork
Ruane-O¿Hora T, Noble MIM, Kelly R, Drake-Holland AJ & Snow HM. ; (2007) Effect of Hyperglycaemia On The Endothelial Glycocalyx Royal Academy of Medicine in Ireland, Summer Meeting, Cork [Details]
(2004)Physiological Society Annual Meeting
Kelly, R and Peim, A and Walz, A and others (2004) Reversal of digoxin cardiac toxicity by an Anticalin (Digical II) in the anaesthetized guinea pig Physiological Society Annual Meeting Cork, [Details]

Published Reports

 YearPublication
(2012)2nd South Africa–United Kingdom cardiovascular workshop.
Kelly-Laubscher R and Burger G and Davies N and Engelbrecht A and Sliwa K and Lecour S and Strijdom H and Hausenloy D (2012) 2nd South Africa–United Kingdom cardiovascular workshop. Cardiovascular Journal of Africa, South Africa. [Details]

Professional Activities

Honours and Awards

 YearTitleAwarding Body
2015Andries Brink-Kaye Award for the most outstanding scientific publication in the Cardiovascular Journal of Africa for 2014 Cardiovascular Journal of Africa

Journal Activities

 JournalRoleTo / From
Cardiovascular Journal Of Africa Referee-
Journal Of Cardiovascular Pharmacology Referee-
Pharmacological Reviews Referee-

Contact details

  • Roisin Kelly
    Lecturer
  • roisinkelly@ucc.ie
  • Dept. Pharmacology & Therapeutics
    Western Gateway Building

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Department of Pharmacology and Therapeutics

Cógaseolaíocht agus Teiripic

2nd Floor, Western Gateway Building, University College Cork, Cork

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