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4. Niall Hyland

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Biography

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Research Interests

My career has resulted in numerous contributions to the scientific research community. My research has shown that targeting GABAB receptors in the central nervous system can modulate brain-gut functioning having first identified the brain regions involved in the innervation of the lower oesophageal sphincter. This work supported the clinical investigation of GABAB receptor agonists in the management of reflux disease. I also described the fundamental roles of the gut hormones Peptide YY (PYY) and PYY(3-36) on gastrointestinal physiology in health and disease (obesity) and I was the first to characterise intestinal secreto-motor responses in germ-free mice, supporting their use as a tool to investigate microbe-host interactions ex vivo (DOI: 10.1111/nmo.12328; published as a Hot Topic; for commentary see, DOI:10.1111/nmo.12366). Over the past 15 years I have developed further capability in the behavioural aspects of the gut-brain connection. Our review describing the interactions between the microbiome and the enteric nervous system (DOI: 10.1016/j.ydbio.2016.06.027; 111 citations) is ranked in the top 100 articles for social media metrics against all other articles published in Developmental Biology in the same year. I have given >30 invited talks at international scientific meetings (e.g., 49th European Society for Paediatric Gastroenterology, Hepatology and Nutrition Meeting; 8th European Paediatric GI Motility Meeting), R&D business collaboration fora (e.g., Global Engage) and educational events (Coloplast Ostomy Days; 800 ostomy care nurses from 20 countries around the world). 

LABORATORY MEMBERS & ALUMNI
Current
Ms Cecilia Delprete (visiting PhD student, 10-21 – 05-22, University of Bologna, Italy)

Former Postgraduate students
Dr Jacinta Walsh (currently, Health Products Regulatory Authority (HPRA), Ireland)
Dr Jonathan Keane (currently, Postdoctoral Fellow, University College Cork, Ireland)
Dr Kevin Lomasney (currently, Bioprocessing Trainer at The National Institute for Bioprocessing Research and Training (NIBRT))
Ms. Siobhan Carroll (currently, Senior QC Associate, Separation Sciences at Amgen

Former Postdoctoral Fellows
Dr Sinead Heuston (currently, Technical Services/Manufacturing Science Representative at Eli Lilly and Company)
Dr Valeria Felice (currently, Senior Researcher at H&H Group)

Laboratory alumni
Dr Barbara Doerr (Research Assistant; currently, Scientist/Toxicologist at Food Standards Agency, UK)
Ms Olivia Artaiz (Research Assistant; currently, PhD candidate, University of Melbourne, Australia)
Ms Eleonora Rizzo (ERASMUS trainee, 02-15 to 07-15, Universita Degli Studi Di Milano)
Mr Florian Kratz (ERASMUS trainee, 03-13 to 06-13, University of Bonn) 
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Publications

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Edited Books

	Year	Publication
	(2016)	The Gut-Brain Axis: Dietary, Probiotic, and Prebiotic Interventions on the Microbiota Niall Hyland & Catherine Stanton (Ed.). (2016) The Gut-Brain Axis: Dietary, Probiotic, and Prebiotic Interventions on the Microbiota Oxford, UK: Academic Press.   [Details]

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Book Chapters

	Year	Publication
	(2004)	'NPY-like peptides, Y receptors and gastrointestinal function' Hyland NP and Cox HM. ; (2004) 'NPY-like peptides, Y receptors and gastrointestinal function' In: Michel MC, ed. Handbook of experimental pharmacology: NPY and related peptides. Heidelberg: Springer. [Details]

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Peer Reviewed Journals

	Year	Publication
	(2023)	'Beta 3-adrenoceptor agonism ameliorates early-life stress-induced visceral hypersensitivity in male rats' Collins JM;Hyland NP;Clarke G;Fitzgerald P;Julio-Pieper M;Bulmer DC;Dinan TG;Cryan JF;O'Mahony SM; (2023) 'Beta 3-adrenoceptor agonism ameliorates early-life stress-induced visceral hypersensitivity in male rats'. Journal of Neurochemistry, [DOI] [Details]
	(2023)	'The Stressed Gut: Region-specific Immune and Neuroplasticity Changes in Response to Chronic Psychosocial Stress' Lobo B;Tramullas M;Finger BC;Lomasney KW;Beltran C;Clarke G;Santos J;Hyland NP;Dinan TG;Cryan JF; (2023) 'The Stressed Gut: Region-specific Immune and Neuroplasticity Changes in Response to Chronic Psychosocial Stress'. Neuro-Gastroenterology and Motility, 29 (1) [DOI] [Details]
	(2023)	'Microbes, oxytocin and stress: Converging players regulating eating behavior' Cuesta-Marti C;Uhlig F;Muguerza B;Hyland N;Clarke G;Schellekens H; (2023) 'Microbes, oxytocin and stress: Converging players regulating eating behavior'. Journal of Neuroendocrinology, [DOI] [Details]
	(2022)	'Making Sense of Quorum Sensing at the Intestinal Mucosal Interface' Uhlig, F;Hyland, NP (2022) 'Making Sense of Quorum Sensing at the Intestinal Mucosal Interface'. Cells, 11 [DOI] [Details]
	(2022)	'Investigation of the gut microbiome, bile acid composition and host immunoinflammatory response in a model of azoxymethane-induced colon cancer at discrete timepoints' Keane, JM;Walsh, CJ;Cronin, P;Baker, K;Melgar, S;Cotter, PD;Joyce, SA;Gahan, CGM;Houston, A;Hyland, NP (2022) 'Investigation of the gut microbiome, bile acid composition and host immunoinflammatory response in a model of azoxymethane-induced colon cancer at discrete timepoints'. British Journal of Cancer, [DOI] [Details]
	(2022)	'Emerging effects of tryptophan pathway metabolites and intestinal microbiota on metabolism and intestinal function' Hyland, NP;Cavanaugh, CR;Hornby, PJ (2022) 'Emerging effects of tryptophan pathway metabolites and intestinal microbiota on metabolism and intestinal function'. Amino Acids, [DOI] [Full Text] [Details]
	(2021)	'The gut microbiome influences the bioavailability of olanzapine in rats' Cussotto, Sofia; Walsh, Jacinta; Golubeva, Anna V.; Zhdanov, Alexander V.; Strain, Conall R.; Fouhy, Fiona; Stanton, Catherine; Dinan, Timothy G.; Hyland, Niall P.; Clarke, Gerard; Cryan, John F.; Griffin, Brendan T. (2021) 'The gut microbiome influences the bioavailability of olanzapine in rats'. Ebiomedicine, 66 [DOI] [Full Text] [Details]
	(2020)	'A Marine-Derived, Multi-mineral Supplement Influences Bacterial Fermentation and Short Chain Fatty Acid ProfileIn Vitro' Felice, VD;O'Gorman, DM;Apajalahti, J;Rinttila, T;O'Brien, NM;Hyland, NP (2020) 'A Marine-Derived, Multi-mineral Supplement Influences Bacterial Fermentation and Short Chain Fatty Acid ProfileIn Vitro'. Journal Of Medicinal Food, [DOI] [Details]
	(2020)	'Gut microbiome-mediated modulation of hepatic cytochrome P450 and P-glycoprotein: impact of butyrate and fructo-oligosaccharide-inulin' Walsh, J;Gheorghe, CE;Lyte, JM;van de Wouw, M;Boehme, M;Dinan, TG;Cryan, JF;Griffin, BT;Clarke, G;Hyland, NP (2020) 'Gut microbiome-mediated modulation of hepatic cytochrome P450 and P-glycoprotein: impact of butyrate and fructo-oligosaccharide-inulin'. Journal of Pharmacy and Pharmacology, [DOI] [Details]
	(2020)	'Nigral overexpression of alpha-synuclein in a rat Parkinson's disease model indicates alterations in the enteric nervous system and the gut microbiome' O'Donovan, SM;Crowley, EK;Brown, JRM;O'Sullivan, O;O'Leary, OF;Timmons, S;Nolan, YM;Clarke, DJ;Hyland, NP;Joyce, SA;Sullivan, AM;O'Neill, C (2020) 'Nigral overexpression of alpha-synuclein in a rat Parkinson's disease model indicates alterations in the enteric nervous system and the gut microbiome'. Neurogastroenterology and Motility, 32 [DOI] [Details]
	(2020)	'Impact of host and environmental factors on ß-glucuronidase enzymatic activity: implications for gastrointestinal serotonin' Walsh, Jacinta; Olavarria-Ramirez, Loreto; Lach, Gilliard; Boehme, Marcus; Dinan, Timothy G.; Cryan, John F.; Griffin, Brendan T.; Hyland, Niall P.; Clarke, Gerard (2020) 'Impact of host and environmental factors on ß-glucuronidase enzymatic activity: implications for gastrointestinal serotonin'. American Journal of Physiology - Gastrointestinal and Liver Physiology, [DOI] [Full Text] [Details]
	(2020)	'Microbial metabolites as molecular mediators of host-microbe symbiosis in colorectal cancer' Keane, Jonathan M.; Joyce, Susan A.; Gahan, Cormac G. M.; Hyland, Niall P.; Houston, Aileen (2020) 'Microbial metabolites as molecular mediators of host-microbe symbiosis in colorectal cancer'. Results And Problems In Cell Differentiation, 69 [DOI] [Full Text] [Details]
	(2019)	'Gut Reactions: Breaking Down Xenobiotic-Microbiome Interactions' Clarke G;Sandhu KV;Griffin BT;Dinan TG;Cryan JF;Hyland NP; (2019) 'Gut Reactions: Breaking Down Xenobiotic-Microbiome Interactions'. Pharmacological reviews, 71 (2) [DOI] [Full Text] [Details]
	(2018)	'When pharmacology meets the microbiome: new targets for therapeutics?' Hyland, Niall P.; Cryan, John F. (2018) 'When pharmacology meets the microbiome: new targets for therapeutics?'. British journal of pharmacology, 175 (24):4401-4403   [DOI] [Full Text] [Details]
	(2018)	'Drug-gut microbiota interactions: implications for neuropharmacology' Walsh, Jacinta; Griffin, Brendan T.; Clarke, Gerard; Hyland, Niall P. (2018) 'Drug-gut microbiota interactions: implications for neuropharmacology'. British journal of pharmacology,   [DOI] [Full Text] [Details]
	(2018)	'Bioaccessibility and Bioavailability of a Marine-Derived Multimineral, Aquamin-Magnesium' Felice VD, O'Gorman DM, O'Brien NM, Hyland N (2018) 'Bioaccessibility and Bioavailability of a Marine-Derived Multimineral, Aquamin-Magnesium'. Nutrients, 10 (7) [DOI] [Details]
	(2017)	'Microbiota-related Changes in Bile Acid & Tryptophan Metabolism are Associated with Gastrointestinal Dysfunction in a Mouse Model of Autism' Golubeva AV;Joyce SA;Moloney G;Burokas A;Sherwin E;Arboleya S;Flynn I;Khochanskiy D;Moya-Pérez A;Peterson V;Rea K;Murphy K;Makarova O;Buravkov S;Hyland NP;Stanton C;Clarke G;Gahan CGM;Dinan TG;Cryan JF; (2017) 'Microbiota-related Changes in Bile Acid & Tryptophan Metabolism are Associated with Gastrointestinal Dysfunction in a Mouse Model of Autism'. Ebiomedicine, 24 [DOI] [Details]
	(2016)	'Quantitative analysis of mucosal oxygenation using ex vivo imaging of healthy and inflamed mammalian colon tissue' Zhdanov AV;Okkelman IA;Golubeva AV;Doerr B;Hyland NP;Melgar S;Shanahan F;Cryan JF;Papkovsky DB; (2016) 'Quantitative analysis of mucosal oxygenation using ex vivo imaging of healthy and inflamed mammalian colon tissue'. Cellular and Molecular Life Sciences, [DOI] [Details]
	(2016)	'Microbe-host interactions: Influence of the gut microbiota on the enteric nervous system' Hyland NP;Cryan JF; (2016) 'Microbe-host interactions: Influence of the gut microbiota on the enteric nervous system'. Developmental Biology, [DOI] [Details]
	(2015)	'Breaking down the barriers: the gut microbiome, intestinal permeability and stress-related psychiatric disorders' Kelly JR;Kennedy PJ;Cryan JF;Dinan TG;Clarke G;Hyland NP; (2015) 'Breaking down the barriers: the gut microbiome, intestinal permeability and stress-related psychiatric disorders'. Frontiers in Cellular Neuroscience, 9 [DOI] [Details]
	(2015)	'Prenatal Stress Induces Subtle Alterations in Major Physiological Systems: a Role for Gut Microbiota?' Golubeva AV, Crampton S, Desbonnet L, Edge D, O’Sullivan O, Lomasney KW, Zhdanov AV, Moloney RD, Borre YE, Cotter PD, Hyland NP, O'Halloran KD, Dinan TG, O’Keeffe GW #, Cryan JF#. (2015) 'Prenatal Stress Induces Subtle Alterations in Major Physiological Systems: a Role for Gut Microbiota?'. Psychoneuroendocrinology, 60 :58-75 [Details]
	(2014)	'Early-life stress selectively affects gastrointestinal but not behavioral responses in a genetic model of brain–gut axis dysfunction' N. P. Hyland, S. M. O'Mahony, D. O'Malley, C. M. O'Mahony, T. G. Dinan and J. F. Cryan. (2014) 'Early-life stress selectively affects gastrointestinal but not behavioral responses in a genetic model of brain–gut axis dysfunction'. Neurogastroenterol & Motility,   [DOI] [Details]
	(2014)	'Microbiota-host interactions in irritable bowel syndrome: epithelial barrier, immune regulation and brain-gut interactions' Hyland NP, Quigley EM, Brint E (2014) 'Microbiota-host interactions in irritable bowel syndrome: epithelial barrier, immune regulation and brain-gut interactions'. World journal of gastroenterology : WJG, 20 (27):8859-8866 [DOI] [Details]
	(2014)	'GABAB receptors in the bladder and bowel: Therapeutic potential for positive allosteric modulators?' Hyland NP, Golubeva AV (2014) 'GABAB receptors in the bladder and bowel: Therapeutic potential for positive allosteric modulators?'. British journal of pharmacology, [DOI] [Details]
	(2014)	'Disturbance of the gut microbiota in early-life selectively affects visceral pain in adulthood without impacting cognitive or anxiety-related behaviors in male rats' O'Mahony SM, Felice VD, Nally K, Savignac HM, Claesson MJ, Scully P, Woznicki J, Hyland NP, Shanahan F, Quigley EM, Marchesi JR, O'Toole PW, Dinan TG, Cryan JF (2014) 'Disturbance of the gut microbiota in early-life selectively affects visceral pain in adulthood without impacting cognitive or anxiety-related behaviors in male rats'. Neuroscience, 277C :885-901 [DOI] [Details]
	(2014)	'Converging effects of a Bifidobacterium and Lactobacillus probiotic strain on mouse intestinal physiology' Lomasney, KW,Cryan, JF,Hyland, NP (2014) 'Converging effects of a Bifidobacterium and Lactobacillus probiotic strain on mouse intestinal physiology'. American Journal Of Physiology-Gastrointestinal And Liver Physiology, 307 :241-247 [DOI] [Details]
	(2013)	'Disodium Cromoglycate Reverses Colonic Visceral Hypersensitivity and Influences Colonic Ion Transport in a Stress-Sensitive Rat Strain' Carroll, SY,O'Mahony, SM,Grenham, S,Cryan, JF,Hyland, NP (2013) 'Disodium Cromoglycate Reverses Colonic Visceral Hypersensitivity and Influences Colonic Ion Transport in a Stress-Sensitive Rat Strain'. Plos One, 8 [DOI] [Full Text] [Details]
	(2013)	'The application of Ussing chambers for determining the impact of microbes and probiotics on intestinal ion transport' Lomasney KW, Hyland NP (2013) 'The application of Ussing chambers for determining the impact of microbes and probiotics on intestinal ion transport'. Canadian Journal of Physiology and Pharmacology, 91 (9):663-670 [DOI] [Details]
	(2012)	'Chymase inhibition as a pharmacological target: A role in inflammatory and functional gastrointestinal disorders?' Heuston S, Hyland NP (2012) 'Chymase inhibition as a pharmacological target: A role in inflammatory and functional gastrointestinal disorders?'. British Journal of Pharmacology, [DOI] [Details]
	(2011)	'The effects of repeated social interaction stress on behavioural and physiological parameters in a stress-sensitive mouse strain' Savignac, HM,Hyland, NP,Dinan, TG,Cryan, JF; (2011) 'The effects of repeated social interaction stress on behavioural and physiological parameters in a stress-sensitive mouse strain'. Behavioural Brain Research, 216 :576-584 [DOI] [Details]
	(2011)	'Functional Dyspepsia-Another Red State! Eosinophils, MacRophages, and Postinfectious Dyspepsia' Craig OF, Hyland NP, Quigley EM; (2011) 'Functional Dyspepsia-Another Red State! Eosinophils, MacRophages, and Postinfectious Dyspepsia'. Gastroenterology, [DOI] [Details]
	(2011)	'Maternal separation as a model of brain-gut axis dysfunction' O'Mahony, SM; Hyland, NP; Dinan, TG; Cryan, JF; (2011) 'Maternal separation as a model of brain-gut axis dysfunction'. Psychopharmacology,   [DOI] [Details]
	(2010)	'Adaptation of intestinal secretomotor function and nutrient absorption in response to diet-induced obesity' Hyland, NP,Rybicka, JM,Ho, W,Pittman, QJ,Macnaughton, WK,Sharkey, KA; (2010) 'Adaptation of intestinal secretomotor function and nutrient absorption in response to diet-induced obesity'. Neurogastroenterology and Motility, 22 [DOI] [Details]
	(2010)	'A Gut Feeling about GABA: Focus on GABA(B) Receptors' Hyland NP and Cryan JF (2010) 'A Gut Feeling about GABA: Focus on GABA(B) Receptors'. Frontiers In Pharmacology,   [DOI] [Details]
	(2009)	'A Mouse Model for Visualization of GABA(B) Receptors' Casanova, E,Guetg, N,Vigot, R,Seddik, R,Julio-Pieper, M,Hyland, NP,Cryan, JF,Gassmann, M,Bettler, B; (2009) 'A Mouse Model for Visualization of GABA(B) Receptors'. Genesis, 47 :595-602 [DOI] [Details]
	(2009)	'A distinct subset of submucosal mast cells undergoes hyperplasia following neonatal maternal separation: a role in visceral hypersensitivity?' Hyland NP, Julio-Pieper M, O'Mahony SM, Bulmer DC, Lee K, Quigley EM, Dinan TG, Cryan JF; (2009) 'A distinct subset of submucosal mast cells undergoes hyperplasia following neonatal maternal separation: a role in visceral hypersensitivity?'. Gut, 58 (7):1029-101 [DOI] [Details]
	(2009)	'Toll-Like Receptor mRNA Expression Is Selectively Increased in the Colonic Mucosa of Two Animal Models Relevant to Irritable Bowel Syndrome' McKernan, DP,Nolan, A,Brint, EK,O'Mahony, SM,Hyland, NP,Cryan, JF,Dinan, TG; (2009) 'Toll-Like Receptor mRNA Expression Is Selectively Increased in the Colonic Mucosa of Two Animal Models Relevant to Irritable Bowel Syndrome'. Plos One, 4 [DOI] [Details]
	(2009)	'Differential adipokine response in genetically-predisposed lean and obese rats during inflammation; a role in modulating experimental colitis?' Hyland NP, Chambers AP, Keenan CM, Pittman QJ, Sharkey KA; (2009) 'Differential adipokine response in genetically-predisposed lean and obese rats during inflammation; a role in modulating experimental colitis?'. American Journal of Physiology - Gastrointestinal and Liver Physiology, [DOI] [Details]
	(2007)	'Neonatal immune challenge exacerbates experimental colitis in adult rats: potential role for TNF-alpha' Spencer SJ, Hyland NP, Sharkey KA, Pittman QJ; (2007) 'Neonatal immune challenge exacerbates experimental colitis in adult rats: potential role for TNF-alpha'. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology, 292 (1):1-15 [DOI] [Details]
	(2007)	'Peptide YY containing enteroendocrine cells and peripheral tissue sensitivity to PYY and PYY(3-36) are maintained in diet-induced obese and diet-resistant rats' Hyland NP, Pittman QJ, Sharkey KA; (2007) 'Peptide YY containing enteroendocrine cells and peripheral tissue sensitivity to PYY and PYY(3-36) are maintained in diet-induced obese and diet-resistant rats'. Peptides, 28 (6):1185-1190 [DOI] [Details]
	(2006)	'Persistent alterations to enteric neural signalling in the colon following resolution of colitis' *Lomax AE, *O'Hara JR, *Hyland NP, Mawe GM, Sharkey KA. ; (2006) 'Persistent alterations to enteric neural signalling in the colon following resolution of colitis'. American journal of physiology. Gastrointestinal and liver physiology, 292 (2):G282-491 [Details]
	(2005)	'The regulation of veratridine-stimulated electrogenic ion transport in mouse colon by neuropeptide Y (NPY), Y1 and Y2 receptors' Hyland NP and Cox HM. ; (2005) 'The regulation of veratridine-stimulated electrogenic ion transport in mouse colon by neuropeptide Y (NPY), Y1 and Y2 receptors'. British Journal of Pharmacology, 146 (5):712-722 [Details]
	(2003)	'Functional consequences of neuropeptide Y Y2 receptor knockout and Y2 antagonism in mouse and human colonic tissues' Hyland NP, Sjöberg F, Tough IR, Herzog H, Cox HM. ; (2003) 'Functional consequences of neuropeptide Y Y2 receptor knockout and Y2 antagonism in mouse and human colonic tissues'. British Journal of Pharmacology, 139 (4):863-871 [Details]
	(2001)	'Site of action of GABA(B) receptor for vagal motor control of the lower esophageal sphincter in ferrets and rats' McDermott CM, Abrahams TP, Partosoedarso E, Hyland N, Ekstrand J, Monroe M, Hornby PJ. ; (2001) 'Site of action of GABA(B) receptor for vagal motor control of the lower esophageal sphincter in ferrets and rats'. Gastroenterology, 120 (7):1749-1762 [Details]
	(2001)	'Organization and neurochemistry of vagal preganglionic neurons innervating the lower esophageal sphincter in ferrets' Hyland NP, Abrahams TP, Fuchs K, et al. ; (2001) 'Organization and neurochemistry of vagal preganglionic neurons innervating the lower esophageal sphincter in ferrets'. Journal of Comparative Neurology, 430 (2):222-234 [Details]

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Conference Publications

	Year	Publication
	(2017)	AD/PDTM 2017, the 13th​ International Conference on Alzheimer's and Parkinson's Diseases and Related Neurological Disorders O’Donovan SM, Crowley E, Browne J, O’Sullivan O, O’Leary OF, Timmons S, Nolan YM, O’Toole PW, Clarke DJ, Hyland NP, Joyce SA, Sullivan AM, O’Neill C (2017) The brain ↔gut axis in Parkinson’s disease: defining gut pathology and the impact of exercise in the rAAV-­α-­synuclein rat model of PD AD/PDTM 2017, the 13th​ International Conference on Alzheimer's and Parkinson's Diseases and Related Neurological Disorders , 29-MAR-17 - 02-APR-17 [Details]
	(2015)	Digestive Disease Week 2015 O'Callaghan G, Fernandes P, Shanahan F, Hyland NP and Houston A (2015) Cross-Talk Between Gamma-Aminobutyric Acid and Prostaglandin E2 in Colon Carcinogenesis Digestive Disease Week 2015 , pp.S356-S357   [DOI] [Details]
	(2014)	Junior Scientists ECNP Workshop on Neuropsychopharmacology 2014, Nice, France Golubeva AV, Crampton SJ, Desbonnet L, Edge D, Lomasney KW, Hyland NP, O'Halloran KD, Dinan TG, O'Keeffe GW, Cryan JF (2014) P.4.011 Differential negative impact of prenatal stress on physiological systems in adulthood Junior Scientists ECNP Workshop on Neuropsychopharmacology 2014, Nice, France [DOI] [Details]
	(2011)	Neuroscience Ireland • Felice VD, Bravo J, Hyland NP, Dinan TG, Cryan JF, O’Mahony SM (2011) Visceral hypersensitivity induced by early-life stress is reduced by a selective 5-HT2b receptor antagonist and is not associated in increased expression of this receptor in brain areas associated with the emotional aspects of pain Neuroscience Ireland [Details]
	(2015)	Proceedings of the British Pharmacological Society Rizzo E., Golubeva AV., Cryan JF., O'Reilly BA., Hyland NP (2015) Microbiota Regulation of Bladder Toll-like Receptor Expression in Male and Female Mice Proceedings of the British Pharmacological Society   [Details]
	(2014)	Society for Neuroscience (SFN) Neuroscience 2014, November 15-19, Washington, USA Borre YE, Hecke Morais L, Golubeva AV, Patterson E, Crispie F, Moloney RD, Scott KA, Stilling R, Hyland NP, Clarke G, Stanton C, Cotter PD, Dinan TG, Cryan JF. (2014) Mode of delivery at birth and behavioural outcomes: Rewiring of the brain-gut-microbiome axis? Society for Neuroscience (SFN) Neuroscience 2014, November 15-19, Washington, USA , 15-NOV-14 - 19-NOV-14 [Details]
	(2014)	Digestive Disease Week Kevin W. Lomasney , John F. Cryan , Niall P. Hyland (2014) Probiotics Influence Colonic Secretomotor Function and Gastrointestinal Physiology in the Mouse: In Vitro and In Vivo Studies With Bifidobacterium Infantis 35624 and Lactobacillus Salivarius UCC118 Digestive Disease Week , pp.S-135-S-136   [DOI] [Details]
	(2013)	Digestive Disease Week Sinead Heuston , Eamonn M. Quigley , Niall P. Hyland (2013) Assessment of Chymase Inhibition on Acute restraint Stress-Induced Visceral Hypersensitivity and Intestinal Dysfunction In Vivo Digestive Disease Week   [DOI] [Details]
	(2013)	ECNP Workshop Golubeva AV, Crampton S, Desbonnet L, Edge D, Lomasney KW, Hyland NP, O'Halloran KD, Dinan TG, O'Keeffe GW, Cryan JF (2013) Differential negative impact of prenatal stress on physiological systems in adulthood ECNP Workshop [Details]
	(2013)	Pharmacology 2013 Florian Kratz, Sinead Heuston, Lis London, Paul Ross, Catherine Stanton, Aileen Houston, Niall Hyland (2013) Bacterial-derived gamma-aminobutyric acid significantly attenuates proliferation of human colon adenocarcinoma cells in vitro Pharmacology 2013 Proceedings of the British Pharmacological Society at http://www.pA2online.org/abstracts/Vol11Issue3abst043P.pdf,   [Details]
	(2012)	Digestive Disease Week Kevin W. Lomasney , John F. Cryan , Niall P. Hyland (2012) γ-Amino-Butyric Acid Regulates Submucosal Cholinergic Signalling and Secretomotor Function in Mouse Colon Digestive Disease Week   [DOI] [Details]
	(2012)	British Pharmacological Society Winter Meeting 2012 NP Hyland, T Inkinen, S Grenham, EK Brint (2012) Toll Like Receptor Ligands Differentially Regulate Expression Of Colonic Epithelial Muscarinic Receptors In a Ligand-Specific and Temporal Manner British Pharmacological Society Winter Meeting 2012 Proceedings of the British Pharmacological Society at http://www.pA2online.org/abstracts/Vol10Issue4abst036P.pdf,   [Details]
	(2012)	Joint International Neurogastroenterology and Motility Meeting, 6-8 September 2012, Bologna, Italy N. HYLAND, S. CARROLL, S. HEUSTON, E. QUIGLEY and J. CRYAN (2012) An investigation of the therapeutic potential of chymase- containing mast cells in a preclinical model of irritable bowel syndrome and their translational relevance Joint International Neurogastroenterology and Motility Meeting, 6-8 September 2012, Bologna, Italy   [Details]
	(2012)	Joint International Neurogastroenterology and Motility Meeting, 6-8 September 2012, Bologna, Italy B. LOBO, M. TRAMULLAS, B.-C. FINGER, K. W. LOMASNEY, J. SANTOS, N. P. HYLAND, T. DINAN and J. F. CRYAN (2012) Psychosocial chronic stress induces intestinal dysmotility and changes in enteric nervous system in proximal colon Joint International Neurogastroenterology and Motility Meeting, 6-8 September 2012, Bologna, Italy   [Details]
	(2012)	Joint International Neurogastroenterology and Motility Meeting, 6-8 September 2012, Bologna, Italy K. LOMASNEY, J. CRYAN and N. HYLAND (2012) Gamma-aminobutyric acid regulates submucosal cholinergic signalling and secretomotor function in mouse colon Joint International Neurogastroenterology and Motility Meeting, 6-8 September 2012, Bologna, Italy   [Details]
	(2012)	Digestive Disease Week Sinead Heuston, Eamonn M. Quigley, Niall P. Hyland (2012) Chymase-Containing Mast Cells are Significantly Increased in Patients With Irritable Bowel Syndrome: A Role in Epithelial Permeability? Digestive Disease Week   [Details]
	(2012)	Digestive Disease Week Ambrose M, Moloney G, Heuston S, Rahman A, Davies JM, Murphy C, Hurley G, Quinlan A, Karras J, Hessel EM, Prinjha R, Lee K, Hyland NP, Shanahan F, Hammarstrom M-L, Melgar S, Nally K (2012) MiR-375 is a Key Regulator of Intestinal Homeostasis in Response to Inflammatory Stress Digestive Disease Week   [Details]
	(2012)	British Pharmacological Society Winter Meeting 2012 Fernandes P, Hyland NP, Houston A (2012) Sensitivity of Human and Murine Colonic Tumour Cell Lines to Gamma-aminobutyric Acid (GABA) In Vitro British Pharmacological Society Winter Meeting 2012 Proceedings of the British Pharmacological Society at http://www.pA2online.org/abstracts/Vol10Issue4abst044P.pdf,   [Details]
	(2011)	British Pharmacological Society Winter Meeting O’Connell S, O’Mahony SM and Hyland NP (2011) 5-HT2B receptors regulate enteric neurotransmission in the submucosal plexus of rat colon British Pharmacological Society Winter Meeting   [Details]
	(2011)	British Pharmacological Society Winter Meeting Lomasney KW, Cryan JF and Hyland NP (2011) Effects of the gut microbiota on colonic secretomotor function British Pharmacological Society Winter Meeting   [Details]
	(2010)	Translational Health Research Conference, UCC, Cork O’Malley, D; Liston, M; Dinan, TG; Cryan, JF; Hyland, NP (2010) CRF1 receptor-dependent activation of submucosal neurones by colonic supernatants from maternally separated rats Translational Health Research Conference, UCC, Cork [Details]
	(2010)	European Neuropsychopharmacology Cryan, J,Bravo, JA,Clarke, G,Hyland, NP,O'Malley, D,O'Mahony, D,Julio-Pieper, M,McKernan, DP,Tramullas, M,Dinan, TG (2010) Animal models of co-morbid depression and irritable bowel syndrome European Neuropsychopharmacology , pp.179-180   [DOI] [Details]
	(2010)	Digestive Disease Week O'Malley, D; Liston, M; Dinan, TG; Cryan, JF; Hyland, NP (2010) CRF1 receptor-dependent activation of submucosal neurones by colonic supernatants from maternally separated rats Digestive Disease Week [Details]
	(2010)	Digestive Disease Week Pruteanu, M; Hyland, NP; Clarke, D; Kiely, B; Shanahan, F; (2010) Bacterial proteolytic profile in inflammatory bowel diseases Digestive Disease Week [Details]
	(2009)	Digestive Disease Week McKernan DP, Nolan A, O'Mahony SM, Hyland NP, Brint E, Dinan TG, Cryan JF.; (2009) Toll-Like Receptor mRNA Expression Is Selectively Increased in the Colonic Mucosa of Two Animal Models of Chronic Stress: Relevance to Irritable Bowel Syndrome Digestive Disease Week [Details]
	(2009)	Digestive Disease Week Hyland NP, Bongiovanni C, O'Mahony CM, Fitzgerald P, Dinan TG, Cryan JF; (2009) The Combined Effects of Neonatal Psychological Stress and An Anxious Phenotype On Visceral Hypersensitivity and Colonic Function in Rats Digestive Disease Week [Details]
	(2009)	Digestive Disease Week Julio-Pieper M, Hyland NP, Cryan JF, Dinan TG; (2009) Group-III Metabotropic Glutamate Receptors Are Expressed in Rodent Colon: A Role in Cholinergically Induced Electrolyte Secretion Digestive Disease Week [Details]
	(2008)	Second Joint International Meeting for Neurogastroenterology and Motility, Lucerne, Switzerland, November 2008 Clarke G, Mahony SM, Hyland NP, Fitzgerald P, Cryan JF, Dinan TG (2008) Visceral pain and beta3 adrenoceptor modulation a role for the kynurenine pathway? Second Joint International Meeting for Neurogastroenterology and Motility, Lucerne, Switzerland, November 2008 [Details]
	(2008)	Second Joint International Meeting for Neurogastroenterology and Motility, Lucerne, Switzerland, November 2008 Hyland, NP, O’ Callaghan K, O’Malley, D, Lee, K, Dinan, TG, Cryan, JF (2008) Differential cholinergic sensitivity in the enteric nervous system in two models of visceral hypersensitivity Second Joint International Meeting for Neurogastroenterology and Motility, Lucerne, Switzerland, November 2008 [Details]
	(2008)	European Behavioural Pharmacology Society Workshop on Behavioural Genetics and Neuropsychiatric Disorders (Cork, Ireland, September 2008) Clarke, G,O'Mahony, S,Hyland, NP,Fitzgerald, P,Dinan, TG,Cryan, JF (2008) Beta3 adrenoceptor modulation of visceral pain - A possible role for the kynurenine pathway? European Behavioural Pharmacology Society Workshop on Behavioural Genetics and Neuropsychiatric Disorders (Cork, Ireland, September 2008) , pp.671-672 [Details]
	(2008)	Digestive Disease Week Hyland NP, Gibney SM, Gosselin RD, Lee K, Dinan TG, Cryan JF (2008) Assessment of colonic secretory function and faecal output in viscerally hypersensitive Wistar Kyoto rats Digestive Disease Week [Details]
	(2008)	Digestive Disease Week Hyland NP, O¿Mahony SM, Bulmer DC, Lee K, Dinan TG & Cryan JF; (2008) Do mast cells contribute to visceral hypersensitivity in adult rats following neonatal psychological stress? Digestive Disease Week San Diego, USA, , 01-JAN-08 - 01-JAN-08 [Details]
	(2008)	Second Joint International Meeting for Neurogastroenterology and Motility, Lucerne, Switzerland, November 2008 Hyland NP, O'Mahony SM, Bulmer DC, Julio-Pieper M, Bongiovanni C, Dinan TG, Cryan JF; (2008) Beta3-adrenoceptor mediated secretion and localisation in the submucosal plexus of descending colon from maternally separated animals Second Joint International Meeting for Neurogastroenterology and Motility, Lucerne, Switzerland, November 2008 [Details]
	(2007)	Digestive Disease Week Hyland NP, Chambers AP, Pittman QJ, Sharkey KA (2007) Diet-induced obesity confers protection against TNBS-induced colitis in rats Digestive Disease Week [Details]
	(2007)	Digestive Disease Week Hyland NP, Rybicka J, Macnaughton WK , Pittman QJ , Sharkey KA. ; (2007) A genetic predisposition to develop diet-induced obesity correlates with altered glucose transport and secretomotor function in a rat model Digestive Disease Week [Details]
	(2006)	Digestive Disease Week Hyland NP, Spencer SJ, Pittman QJ and Sharkey KA (2006) Neonatal lipopolysaccharide increases the severity of TNBS-induced colitis in adult rats Digestive Disease Week [Details]
	(2003)	British Pharmacological Society Hyland NP, Tough IR, Cox HM. (2003) Capsaicin-induced changes in ion transport across colonic mucosae are unaffected by neuropeptide Y Y1 or Y2 antagonism or Y1, Y2 or Y4 receptor knockout British Pharmacological Society   [Details]
	(2003)	Enteric Nervous System 2003 Cox HM, Tough IR, Hyland NP. ; (2003) Neuropeptide Y Y1 and Y2 receptors mediate inhibitory tone in murine and human colon mucosae Enteric Nervous System 2003 , pp.195-237 [Details]
	(2003)	British Pharmacological Society Hyland NP, Cox HM. ; (2003) Differential role of Y1 and Y2 receptors mediating neuropeptide Y`s contribution to veratridine-induced ion transport across mouse colon British Pharmacological Society [Details]
	(2002)	British Pharmacological Society Hyland NP, Herzog H, Cox HM. ; (2002) Decreased sensitivity to pancreatic polypeptide in colonic mucosa from Y2 receptor knockout mice British Pharmacological Society [Details]
	(2002)	British Journal of Pharmacology Hyland NP, Cox HM. ; (2002) Effects of veratridine upon electrogenic ion transport across NPY knockout and wildtype mouse descending colon British Journal of Pharmacology [Details]
	(2000)	Digestive Disease Week Hornby PJ, Hyland NP, Fuchs KM, et al. (2000) Co-innervation of both the lower esophageal sphincter and gastric fundus by vagal preganglionic neurons in ferrets Digestive Disease Week [Details]
	(2000)	Digestive Disease Week Abrahams TP, Hyland NP, Hornby PJ (2000) Presence of NO synthase in vagal motor neurons innervating the lower esophageal sphincter in ferrets Digestive Disease Week [Details]
	(1999)	Society for Neuroscience AbrahamsTP, J Ekstrand, NP Hyland and PJ Hornby. ; (1999) Immunocytochemical localization of GABAB receptor in ferrets dorsal vagal complex and functional role in control of lower esophageal sphincter pressure Society for Neuroscience [Details]
	(1999)	Digestive Disease Week Hyland NP, R.H.Quinn, T.P. Abrahams and P.J.Hornby (1999) Vagal motor neurons innervating the lower esophageal sphincter in ferrets Digestive Disease Week [Details]

‍

Professional Activities

‍

Employment

	Employer	Position	From / To
	University College Cork	Senior Lecturer	13-MAY-18 /
	Pharmacology & Therapeutics	Lecturer in Pharmacology	01-AUG-08 / 13-MAY-18
	Alimentary Pharmabiotic Centre (University College Cork)	Senior Postdoctoral Fellow	01-JAN-07 / 01-AUG-08
	University of Calgary, Canada	Postdoctoral Fellow	01-JAN-04 / 01-JAN-07
	Louisiana State University Medical Center, USA	Visiting Research Fellow	01-JUN-98 / 01-SEP-99

‍

Education

	Year	Institution	Qualification	Subject
	2012	University College Cork	Postgrad Cert. in Teaching & Learning in HE	Teaching & Learning in HE
	2004	University of London (King's College London), London, UK.	PHD	Pharmacology
	2000	University of Ulster, Coleraine, Northern Ireland.	BSC (HONS)	Biomedical Sciences
	2000	University of Ulster, Coleraine, Northern Ireland.	Diploma	Industrial Studies

‍

Conference Contributions

	Year	Publication
	(2016)	Society on NeuroImmune Pharmacology: SNIP, Krakow, Poland, April 4th - 6th, 2016, NIall Hyland (2016) Invited speaker; Mast cells, microbes and the gut-brain axis in symposium entitled Neuroinflammation and the Gut: What is its relevance to HIV infection, neurological pathology, and therapy? Neurodegenerative Responses to Viral Infections and Therapeutics. [Invited Oral Presentation], Society on NeuroImmune Pharmacology: SNIP, Krakow, Poland, April 4th - 6th, 2016, Krakow, Poland , 06-APR-16 - 09-APR-16. [Details]
	(2016)	Probiota 2016, Amsterdam, The Netherlands, Feb 2nd - 4th, 2016, NIall Hyland (2016) Chairperson - Panel discussion Opportunities for life?. [Chair Sessions at Symposia], Probiota 2016, Amsterdam, The Netherlands, Feb 2nd - 4th, 2016, Amsterdam, The Netherlands . [Details]
	(2016)	49th Annual Meeting of the European Society for Paediatric Gastroenterology, Hepatology and Nutrition in Athens, 25–28 May 2016, NIall Hyland (2016) Invited speaker; Influence of the microbiome on host gut function and physiology in Basic Science Symposium: From bench to bedside in paediatric gastroenterology. [Oral Presentation], 49th Annual Meeting of the European Society for Paediatric Gastroenterology, Hepatology and Nutrition in Athens, 25–28 May 2016, Athens, Greece , 25-MAY-16 - 28-JUL-16. [Details]
	(2015)	Pharmacology 2015, NIall Hyland (2015) Annual Meeting of the British Pharmacological Society - Chair Oral Sessions; Referee Poster Presentations. [Conference Organising Committee Member], Pharmacology 2015, London . [Details]
	(2015)	ASCEPT-BPS Joint Scientific Meeting, Niall P Hyland (2015) Scientific Organising Committee; This meeting represents the first joint meeting between the Australasian Society of Clinical and Experimental Pharmacologists and Toxicologists (ASCEPT) and the British Pharmacological Society (BPS). [Conference Organising Committee Member], ASCEPT-BPS Joint Scientific Meeting, Hong Kong . [Details]
	(2014)	Probiota 2014, Niall P Hyland (2014) Speaker; The gut-brain axis: The potential mood-boosting effects of pre-probiotics. [Invited Oral Presentation], Probiota 2014, Netherlands . [Details]
	(2014)	Pharmacology 2014, Niall P Hyland (2014) Member of Meetings Committee; Pharmacology attracts around 900 scientists each year, mostly from the UK but also many from across Europe and from overseas. The meeting includes a selection of topical symposia, plenary lectures, free oral communications and poster sessions which cover the many aspects of pharmacology from basic to clinical science. [Conference Organising Committee Member], Pharmacology 2014, United Kingdom . [Details]
	(2014)	2nd World Congress on Targeting Microbiota, Niall P Hyland (2014) Speaker; Mind-altering microorganisms: the impact of the gut microbiota on brain and behaviour. [Plenary Lecture], 2nd World Congress on Targeting Microbiota, France . [Details]
	(2014)	Digestive Disease Week, Niall P Hyland (2014) Lecture presentation as part of the Neurogastroenterology & Motility Distinguished Abstract Plenary at Digestive Disease Week held in Chicago. [Plenary Lecture], Digestive Disease Week, USA . [Details]
	(2014)	Probiota 2015, Niall P Hyland (2014) Scientific Committee; Probiota is the leading annual event for the global prebiotic, probiotic and the microbiota focused food and pharma industries. [Conference Organising Committee Member], Probiota 2015, Netherlands . [Details]
	(2013)	Pharmacology 2013, Niall P Hyland (2013) Referee for poster prizes; Pharmacology 2013 (formerly the BPS Winter Meeting) attracts around 800 scientists each year, mostly from the UK but also many from across Europe and from overseas. The meeting includes a selection of topical symposia, plenary lectures, free oral communications and poster sessions which cover the many aspects of pharmacology from basic to clinical science. [Referee], Pharmacology 2013, United Kingdom . [Details]
	(2012)	Digestive Disease Week, Niall P Hyland (2012) American Gastroenterological Association, Abstract Review Committee; Physiology of the GI Tract: Motility, Secretion, Sensation section. [Referee], Digestive Disease Week, USA . [Details]
	(2012)	Digestive Disease Week, Niall P Hyland (2012) American Gastroenterological Association Abstract Review Committee for the Digestive Disease Week annual convention; Brain-Gut Interactions and Neuroimaging section. [Referee], Digestive Disease Week, USA . [Details]
	(2012)	Digestive Disease Week, Niall P Hyland (2012) Symposium Co-chair, Physiology of the GI Tract: Motility Secretion Sensation Research Forum. [Chair Sessions at Symposia], Digestive Disease Week, USA . [Details]
	(2012)	XIIth Little Brain Big Brain September 4-6, 2012, Leuven, Belgium, Niall P Hyland (2012) Speaker; An investigation of the therapeutic potential of chymase-containing mast cells in a preclincal model of irritable bowel syndrome and their translational relevance. [Oral Presentation], XIIth Little Brain Big Brain September 4-6, 2012, Leuven, Belgium, Belgium . [Details]
	(2012)	Joint International Neurogastroenterology and Motility Meeting, 6-8 September 2012, Bologna, Italy, Niall P Hyland (2012) Best of Little Brain Big Brain - Selected Speaker. [Invited Oral Presentation], Joint International Neurogastroenterology and Motility Meeting, 6-8 September 2012, Bologna, Italy, Italy . [Details]
	(2011)	Johnson & Johnson Corporate Office of Science And Technology Microbiome Symposium, Niall P Hyland (2011) Speaker; The microbiome-gut-brain axis: From bowel to behaviour. [Invited Oral Presentation], Johnson & Johnson Corporate Office of Science And Technology Microbiome Symposium, USA . [Details]
	(2011)	Digestive Disease Week, Niall P Hyland (2011) American Gastroenterological Association Abstract Review Committee for the Digestive Disease Week annual convention; Brain-Gut Interactions and Neuroimaging section. [Referee], Digestive Disease Week, USA . [Details]
	(2010)	Digestive Disease Week, Niall P Hyland (2010) American Gastroenterological Association Abstract Review Committee for the Digestive Disease Week annual convention; Brain-Gut Interactions and Neuroimaging section. [Referee], Digestive Disease Week, USA . [Details]
	(2010)	Digestive Disease Week, Niall P Hyland (2010) Symposium Co-chair, Enteric Nervous System and Enteroendocrine Signaling in the Gut Research Forum. [Chair Sessions at Symposia], Digestive Disease Week, USA . [Details]
	(2009)	Digestive Disease Week, Niall P Hyland (2009) American Gastroenterological Association Abstract Review Committee for the Digestive Disease Week annual convention; Brain-Gut Interactions and Neuroimaging section. [Referee], Digestive Disease Week, USA . [Details]
	(2009)	Little brain-Big brain XI, a satellite symposium of the International Society of Neurogastroenterology and Motility Meeting, Kenosha Wisconson, USA, September 2009, Niall P Hyland (2009) Speaker; The combined effects of neonatal psychological stress and an anxious phenotype on visceral hypersensitivity and colonic function in rats. [Oral Presentation], Little brain-Big brain XI, a satellite symposium of the International Society of Neurogastroenterology and Motility Meeting, Kenosha Wisconson, USA, September 2009, USA . [Details]
	(2009)	International Society of Neurogastroenterology and Motility Meeting, Chicago, September 2009, Niall P Hyland (2009) Speaker; The combined effects of neonatal psychological stress and an anxious phenotype on visceral hypersensitivity and colonic function in rats. [Oral Presentation], International Society of Neurogastroenterology and Motility Meeting, Chicago, September 2009, USA . [Details]
	(2009)	Digestive Disease Week, Niall P Hyland (2009) Symposium Co-chair, Brain-Gut Interactions and Neuroimaging Research Forum. [Chair Sessions at Symposia], Digestive Disease Week, USA . [Details]
	(2008)	Irish Society of Gastroenterology Spring Conference, Hyland NP, O¿Mahony SM, Bulmer DC, Lee K, Dinan TG & Cryan JF; (2008) Do mast cells contribute to visceral hypersensitivity in adult rats following neonatal psychological stress?. [Poster Presentation], Irish Society of Gastroenterology Spring Conference, Sligo, Ireland , 01-APR-08 - 01-APR-08. [Details]
	(2008)	All Ireland Schools of Pharmacy Research Conference, Savignac HM, Hyland NP, Dinan TG & Cryan JF (2008) Social stress induces mild colonic damage and altered anti-inflammatory cytokines in the mouse. [Poster Presentation], All Ireland Schools of Pharmacy Research Conference, Cork, Ireland , 01-APR-08 - 01-APR-08. [Details]
	(2008)	Digestive Disease Week, Niall P Hyland (2008) American Gastroenterological Association Abstract Review Committee for the Digestive Disease Week annual convention; Brain-Gut Interactions and Neuroimaging section. [Referee], Digestive Disease Week, USA . [Details]
	(2007)	The Irish Society of Gastroenterology Winter meeting, Savignac HM, Hyland NP, Dinan TG, Cryan JF ; (2007) Social stress induces mild colonic damage and altered pro- and anti-inflammatory cytokines in the mouse. [Poster Presentation], The Irish Society of Gastroenterology Winter meeting, Clontarf Castle Hotel, Dublin, Ireland , 01-NOV-07 - 01-NOV-07. [Details]
	(2007)	Irish Society of Gastroenterology, Winter Meeting, Hyland NP, Dinan TG, Cryan JF; (2007) Stress susceptible Wistar Kyoto rats display altered epithelial cholinergic sensitivity in the distal colon. [Poster Presentation], Irish Society of Gastroenterology, Winter Meeting, Dublin, Ireland , 01-DEC-07 - 01-DEC-07. [Details]
	(2006)	Canadian Association of Gastroenterology, Research Topics in GI Disease VI, Niall P Hyland (2006) Small intestinal secretory and absorptive function is significantly altered in outbred diet-induced obese compared to diet resistant rats. [Oral Presentation], Canadian Association of Gastroenterology, Research Topics in GI Disease VI, Ontario, Canada , 01-OCT-06 - 31-OCT-06. [Details]
	(2006)	Shaffer Awards, University of Calgary, Niall P Hyland (2006) Neonatal immune challenge exacerbates colonic damage and elevates plasma TNFa during TNBS-colitis in adult rats. [Oral Presentation], Shaffer Awards, University of Calgary, University of Calgary, Canada , 01-APR-06 - 30-APR-06. [Details]
	(2006)	Brain-Gut Interactions, St. Annes College, Oxford, UK, *Lomax AE, *O'Hara JR, *Hyland NP, Mawe GM, Sharkey KA. ; (2006) Persistent alterations to enteric neural signalling in the colon following resolution of TNBS colitis. [Oral Presentation], Brain-Gut Interactions, St. Annes College, Oxford, UK, St. Annes College, Oxford, UK , 01-JUL-06 - 31-JUL-06. [Details]
	(2005)	Gastrointestinal Research Group and Immunology Research Group first joint research symposium, University of Calgary, Niall P Hyland (2005) Neonatal lipopolysaccharide increases the severity of TNBS-induced colitis in adult rats. [Oral Presentation], Gastrointestinal Research Group and Immunology Research Group first joint research symposium, University of Calgary, Kananaskis, Alberta, Canada , 01-OCT-05 - 31-OCT-05. [Details]

‍

Journal Activities

	Journal	Role	To / From
	British Journal Of Pharmacology	Editor	-
	British Journal Of Pharmacology	Guest Editor	-
	Frontiers In Neuroscience	Member of Editorial Board	-
	European Journal Of Pain	Referee	-
	European Neuropsychopharmacology	Referee	-
	British Journal Of Pharmacology	Referee	-
	Neuropharmacology	Referee	-
	American Journal Of Physiology-Regulatory Integrative And Comparative Physiology	Referee	-
	Plos One	Referee	-
	Bmc Gastroenterology	Referee	-
	American Journal Of Physiology-Gastrointestinal And Liver Physiology	Referee	-
	The Journal Of Physiology	Referee	-
	Marine Drugs	Referee	-
	Nutritional Neuroscience	Referee	-
	Scandinavian Journal Of Gastroenterology	Referee	-
	Psychopharmacology	Referee	-
	Neurogastroenterol & Motility	Referee	-

‍

Professional Associations

	Association	Function	From / To
	British Pharmacological Society	Vice President – Meetings (2017-2020)	/
	British Pharmacological Society	Non-Trustee member of Council (2017- 2020)	/
	European Society of Neurogastroenterology and Motility (ESNM) Steering Committee Member and National Representative for Ireland, European Society of Neurogastroenterology and Motility	Steering Committee Member and National Representative for Ireland (2015-2020)	/
	British Pharmacological Society	Finance Committee Member (2017-2019)	/
	British Pharmacological Society	Committee Member, British Pharmacological Society Meetings Committee (2012-2016)	/
	British Pharmacological Society	Co-Chair, Integrated Systems Pharmacology Affinity Group, British Pharmacological Society (2015-2017)	/
	American Gastroenterological Association (AGA)	AGA Institute Council Section Councillor (2014 – 2016)	/
	European Society of Neurogastroenterology and Motility	Member	/
	British Pharmacological Society	Member	/

‍

Consultancy

	Client	Description
	Janssen Pharmaceutical Companies of Johnson and Johnson
	Steigerwald part of Bayer group

‍

Other Activities

	Description
	French National Research Agency (ANR) - Generic Call - Grant Reviewer
	Grant Reviewer Royal Netherlands Academy of Arts and Sciences (KNAW) - Programme of Strategic Scientific Alliances
	Reviewer in the evaluation of pre-proposals and full proposals - JPI HDHL funding initiative “Interrelation of the Intestinal Microbiome, Diet and Health” (HDHL-INTIMIC).
	European Research Council - external referee ERC Starting, Consolidator and Advanced Grant Calls 2016.
	Grant Reviewer Fonds National de la Recherche (FNR; Luxembourg) - CORE scheme
	Research Foundation - Flanders (Fonds Wetenschappelijk Onderzoek - Vlaanderen, FWO
	Israel Science Foundation (Individual Research Grants)
	Grant Reviewer European Research Council (ERC) -  ERC Starting Grants
	Grant Reviewer National Science Centre Poland - HARMONIA funding scheme
	Grant Reviewer NC3R (UK)
	Grant Reviewer World Cancer Research Fund International
	Grant Reviewer Medical Research Council (UK)

‍

Committees

	Committee	Function	From / To
	European Society of Neurogastroenterology & Motility	Steering Committee Member	/
	Departmental Graduate Studies Committee		/
	BPharm Programme Board member		/
	Graduate Entry to Medicine (GEM)Teaching and Oversight Committee		/
	American Gastroenterological Association Abstract review committee for the Digestive Disease Week annual convention; Brain-Gut Interactions and Neuroimaging section.		/
	ASCEPT-BPS Joint Scientific Meeting Committee	Member	/
	Probiota Scientific Committee	Member (Chair 2015)	/

‍

Honours and Awards

	Year	Title	Awarding Body
	2022	Honorary Fellowship, British Pharmacological Society	British Pharmacological Society
	2022	Editors’ Performance Award, British Journal of Pharmacology	British Journal of Pharmacology
	2022	Nominee, UCC President's Award for Excellence in Teaching	University College Cork
	2021	2021 – Fellowship, British Pharmacological Society	British Pharmacological Society
	2018	Failte Ireland Conference Ambassador Award	Failte Ireland
	2008	Poster of distinction (American Gastroenterological Association)	Neurogastroenterology & Motility Joint International Meeting, Lucerne, Switzerland
	2004	Research Initiative Award, Canadian Association of Gastroenterology	Canadian Association of Gastroenterology
	2007	Poster of distinction (American Gastroenterological Association)	American Gastroenterological Association,
	2006	Student Choice Award for best oral presentation (Shaffer Research Award)	Gastrointestinal Research Group, University of Calgary, Shaffer Awards
	2003	Travel Bursary (Merck Eurolab)	Merck Eurolab
	2002	Oral communication prize (King's College London, School of Biomedical Sciences)	Guy¿s King¿s and St. Thomas¿ School of Biomedical Sciences
	2001	Poster prize (6th International Neuropeptide Y Conference)	6th International Neuropeptide Y Conference
	2001	Travel Bursary (Merck Eurolab)	Merck Eurolab
	1999	Travel Award (Louisiana State University Medical Center, Center for Neuroscience Excellence)	Louisiana State University Medical Center, Center for Neuroscience Excellence
	2009	Poster of Distinction (American Gastroenterological Association)	American Gastroenterological Association

‍

Languages

	Language	Reading	Writing	Speaking
	English

‍

Teaching Activities

‍

Teaching Interests

Curriculum Development
2016, Member of Delphi Expert Group - British Pharmacological Society core undergraduate pharmacology curriculum project.


Undergraduate:

Mr. Florian Kratz (March 2013 to June  2013), University of Bonn, "Sensitivity of human and murine colonic tumour cell lines to gamma-aminobutyric acid (GABA) in vitro".
















‍

Recent Postgraduates

	Graduation Year	Student Name	Institution	Degree Type	Thesis Title
	2014	Kevin Lomasney		PHD	THE IMPACT OF HOST-MICROBE INTERACTIONS ON MURINE COLONIC SECRETOMOTOR FUNCTION
	2012	Siobhan Carroll		MSc	PHYSIOLOGICAL STUDIES OF GASTROINTESTINAL MAST CELLS: RELEVANCE TO IRRITABLE BOWEL SYNDROME

‍

Research Information

‍

Internal Collaborators

	Name	Institute	Country
	Prof. John Cryan	University College Cork	IRELAND
	Prof. Timothy Dinan	University College Cork	IRELAND
	Dr. Siobhain O'Mahony	University College Cork	IRELAND
	Dr. Gerard Clarke	University College Cork	IRELAND
	Dr. Aileen Houstan	University College Cork	IRELAND
	Dr. Cormac Gahan	University College Cork	IRELAND
	Dr Susan Joyce	University College Cork	IRELAND
	Prof. Dmitri B. Papkovsky	University College Cork	IRELAND

‍

External Collaborators

	Name	Organisation / Institute	Country
	Dr. Denise O'Gorman	Marigot Ltd.	IRELAND