University College Cork Logo

Physiology

Research Profiles

Prof Edward James Johns BSc, PhD, DSc

  • Crest on Main UCC Gates
  • Students on Campus
  • UCC Clock Tower
  • President's Garden

Prof Edward James Johns BSc, PhD, DSc

 

Book Chapters

Izzo, Sica and Black (2008) 'Renal Sympathetic nerves and Extracellular Fluid Volume Regulation' In: Hypertension Primer. Philadelphia: Lippincott Williams and Wilkins. [Details]
Burnier (2008) 'Neural Control of Sodium Balance' In: Sodium in Health and Disease. New York: Informa Healthcare. [Details]
Alpern and Hebert (2008) 'Neural Control of Renal Function' In: Seldin and Giebisch's The Kidnsy. London: Academic Press (Elsevier). [Details]
 

Peer Reviewed Journals

Salman, IM,Ameer, OZ,Sattar, MA,Abdullah, NA,Yam, MF,Najim, HS,Abdulkarim, MF,Abdullah, GZ,Kaur, G,Khan, MAH,Johns, EJ (2011) 'Characterization of renal hemodynamic and structural alterations in rat models of renal impairment: role of renal sympathoexcitation'. Journal of nephrology, 24 :68-77. [DOI] [Details]
Abdulla, MH,Sattar, MA,Abdullah, NA,Khan, AH,Swarup, KRLA,Rathore, HA,Kazi, RN,Basri, F,Johns, EJ (2011) 'Effect of renal sympathetic nerve on adrenergically and angiotensin II-induced renal vasoconstriction in normal Wistar-Kyoto rats'. Rna-A Publication of The Rna Society, 116 :18-25. [DOI] [Details]
Kazi, RN,Sattar, MA,Abdullah, NA,Khan, MAH,Rathore, HA,Abdulla, MH,Salman, IM,Johns, EJ (2011) 'A Special Focus on the Role of alpha(1D)-Adrenoreceptors in the Assessment of Renal Tubular Sodium Re-absorptive Responses in Spontaneously Hypertensive Rats Subjected to High Sodium Diet'. Rna-A Publication of The Rna Society, 131 :431-436. [Details]
Abdulla, MH,Sattar, MA,Abdullah, NA,Khan, MAH,Swarup, KRLA,Johns, EJ (2011) 'The contribution of alpha(1B)-adrenoceptor subtype in the renal vasculature of fructose-fed Sprague-Dawley rats'. Journal of Nutrition, 50 :251-260. [DOI] [Details]
Houghton, BL,Johns, EJ (2011) 'The pressor and renal sympathetic nerve responses to vascular and spinal V-1 receptor activation after manipulation of dietary sodium intake'. Rna-A Publication of The Rna Society, 29 :915-921. [DOI] [Details]
Salman, IM,Ameer, OZ,Sattar, MA,Abdullah, NA,Yam, MF,Abdullah, GZ,Abdulkarim, MF,Khan, MAH,Johns, EJ (2011) 'Renal Sympathetic Nervous System Hyperactivity in Early Streptozotocin-Induced Diabetic Kidney Disease'. Urology, 30 :438-446. [DOI] [Details]
Kazi, RN,Sattar, MA,Abdullah, NA,Rathore, HA,Kolla, AS,Hussain, NM,Abdulla, MH,Salman, IM,Khan, AH,Johns, EJ (2011) 'Influence of High Dietary Sodium Intake on Functional Contribution of Renal alpha 1 alpha-Adrenoceptor of SHR'. Advances In Clinical and Experimental Medicine, 20 :47-56. [Details]
Abdulla, MH,Sattar, MA,Abdullah, NA,Khan, MAH,Abd Allah, HH,Johns, EJ (2010) 'The interaction between renin-angiotensin system and sympathetic nervous system in the systemic circulation of conscious Sprague-Dawley rats'. Healthmed, 4 :328-334. [Details]
Salman, IM,Ameer, OZ,Sattar, MA,Abdullah, NA,Yam, MF,Najim, HS,Khan, AH,Johns, EJ (2010) 'Role of the renal sympathetic nervous system in mediating renal ischaemic injury-induced reductions in renal haemodynamic and excretory functions'. Log, 42 :259-266. [DOI] [Details]
Houghton, BL,Huang, CL,Johns, EJ (2010) 'Influence of dietary sodium on the blood pressure and renal sympathetic nerve activity responses to intracerebroventricular angiotensin II and angiotensin III in anaesthetized rats'. Experimental Physiology, 95 :282-295. [DOI] [Details]
Salman, IM,Sattar, MA,Abdullah, NA,Ameer, OZ,Basri, F,Hussain, NM,Khan, MAH,Yam, MF,Swarup, KRLA,Rathore, HA,Kazi, RN,Salman, HM,Johns, EJ (2010) 'Renal functional & haemodynamic changes following acute unilateral renal denervation in Sprague Dawley rats'. Rna-A Publication of The Rna Society, 131 :76-82. [Details]
Salman, IM,Sattar, MA,Ameer, OZ,Abdullah, NA,Yam, MF,Salman, HM,Khan, MAH,Johns, EJ (2010) 'Role of norepinephrine & angiotensin II in the neural control of renal sodium & water handling in spontaneously hypertensive rats'. Rna-A Publication of The Rna Society, 131 :786-792. [Details]
Salman, IM,Sattar, MA,Abdullah, NA,Ameer, OZ,Basri, F,Hussain, NM,Yam, MF,Swarup, KRLA,Rathore, HA,Kazi, RN,Khan, MAH,Johns, EJ (2010) 'Role of renal sympathetic nervous system in the control of renal potassium handling'. Rna-A Publication of The Rna Society, 23 :291-296. [Details]
Johns, EJ,O'Shaughnessy, B,O'Neill, S,Lane, B,Healy, V (2010) 'Impact of elevated dietary sodium intake on NAD(P)H oxidase and SOD in the cortex and medulla of the rat kidney'. American Journal of Physiology-Regulatory Integrative and Comparative Physiology, 299 :234-240. [DOI] [Details]
Salman, IM,Sattar, MA,Abdullah, NA,Ameer, OZ,Yam, MF,Kaur, G,Khan, MAH,Johns, EJ (2010) 'Renal Ischemic Injury Affects Renal Hemodynamics and Excretory Functions in Sprague Dawley Rats: Involvement of Renal Sympathetic Tone'. Renal Failure, 32 :96-102. [DOI] [Details]
Salman, IM,Sattar, MA,Abdullah, NA,Ameer, OZ,Abdulla, MH,Khan, MAH,Johns, EJ (2009) 'Quantification of Acute Renal Denervation Diuresis and Natriuresis in Sprague Dawley and Spontaneously Hypertensive Rats'. International Journal of Pharmaceutics, 5 :30-36. [Details]
Abdulla, MH,Sattar, MA,Abdullah, NA,Khan, MAH,AbdAllah, HH,Johns, EJ (2009) 'Chronic treatment with losartan and carvedilol differentially modulates renal vascular responses to sympathomimetics compared to treatment with individual agents in normal Wistar Kyoto and spontaneously hypertensive rats'. European Journal of Pharmacology, 612 :69-74. [DOI] [Details]
Khan, AH,Sattar, MA,Abdullah, NA,Johns, EJ (2009) 'EFFECT OF CALCIUM CHANNEL BLOCKADE ON ADRENERGICALLY INDUCED RENAL VASOCONSTRICTION IN RAT MODELS OF RENAL IMPAIRMENT'. Clinical and Experimental Pharmacology and Physiology, 36 :501-508. [DOI] [Details]
Abdulla, MH,Sattar, MA,Khan, MAH,Abdullah, NA,Johns, EJ (2009) 'Influence of sympathetic and AT(1)-receptor blockade on angiotensin II and adrenergic agonist-induced renal vasoconstrictions in spontaneously hypertensive rats'. Acta Physiologica, 195 :397-404. [DOI] [Details]
Salman, IM,Sattar, MA,Abdullah, NA,Ameer, OZ,Abdulla, MH,Basri, F,Hussain, NJM,Khan, MAH,Yam, MF,Swarup, KRLA,Rathore, HA,Kazi, RN,Sriramaneni, RN,Johns, EJ (2009) 'The Role of Renal Sympathetic Nerve Activity in Mediating Renal Hemodynamic Alterations in Rat Models of Renal Impairment'. Advances In Clinical and Experimental Medicine, 18 :205-214. [Details]
Walsh, SK,English, FA,Johns, EJ,Kenny, LC (2009) 'Plasma-Mediated Vascular Dysfunction in the Reduced Uterine Perfusion Pressure Model of Preeclampsia A Microvascular Characterization'. Hypertension, 54 :345-264. [DOI] [Details]
Khan, MAH,Sattar, MA,Abdullah, NA,Abdulla, MH,Salman, IM,Kazi, RN,Swarup, KRLA,Rathore, HA,Basri, F,Hussain, NM,Dewa, A,Johns, EJ (2009) 'Functional Subtypes of Renal alpha(1)-Adrenoceptor in Spontaneously Hypertensive Rats with Streptozotocin-Induced Experimental Diabetic Nephropathy'. Blood, 32 :349-359. [DOI] [Details]
Kompanowska-Jezierska, E,Wolff, H,Kuczeriszka, M,Gramsbergen, JB,Walkowska, A,Johns, EJ,Bie, P (2008) 'Renal nerves and nNOS: roles in natriuresis of acute isovolumetric sodium loading in conscious rats'. American Journal of Physiology-Regulatory Integrative and Comparative Physiology, 294 :1130-1139. [DOI] [Details]
Knight, S,Johns, EJ (2008) 'Renal functional responses to ischaemia-reperfusion injury in normotensive and hypertensive rats following non-selective and selective cyclo-oxygenase inhibition with nitric oxide donation'. Clinical and Experimental Pharmacology and Physiology, 35 :11-16. [Details]
Armenia, A,Sattar, MA,Abdullah, NA,Khan, MAH,Johns, EJ (2008) 'Functional subtypes of renal alpha(1)-adrenoceptor in diabetic and non-diabetic 2K1C Goldblatt renovascular hypertension'. Acta Pharmacologica Sinica, 29 :564-572. [DOI] [Details]
Khan, MAH,Sattar, MA,Abdullah, NA,Johns, EJ (2008) 'alpha(1B)-adrenoceptors mediate adrenergically-induced renal vasoconstrictions in rats with renal impairment'. Acta Pharmacologica Sinica, 29 :193-203. [DOI] [Details]
Khan, MAH,Sattar, MA,Abdullah, NA,Johns, EJ (2008) 'Influence of combined hypertension and renal failure on functional alpha(1)-adrenoceptor subtypes in the rat kidney'. British Journal of Pharmacology, 153 :1232-1241. [DOI] [Details]
Li, YT,Qiu, JH,Zhuo, Y,Johns, EJ,Tao, Z (2008) 'Long-range correlation of renal sympathetic nerve activity in both conscious and anesthetized rats'. Journal of Neuroscience Methods, 172 :131-136. [DOI] [Details]
Hiong, LC,Voon, KL,Abdullah, NA,Sattar, MA,Rahman, NA,Khan, AH,Johns, EJ (2008) 'Effect of TGF-beta 1 antisense oligodeoxynucleotide on renal function in chronic renal failure rats'. Acta Pharmacologica Sinica, 29 :451-457. [DOI] [Details]
Flanagan, ET,Buckley, MM,Aherne, CM,Lainis, F,Sattar, M,Johns, EJ (2008) 'Impact of cardiac hypertrophy on arterial and cardiopulmonary baroreflex control of renal sympathetic nerve activity in anaesthetized rats'. Experimental Physiology, 93 :1058-1064. [DOI] [Details]
Lazahari, MIA,Sattar, MA,Abdullah, NA,Khan, MAH,Johns, EJ (2008) 'Clonidine and a novel clonidine analog AL-12 cause sympathoinhibition in spontaneously hypertensive and diabetic spontaneously hypertensive rats'. Methods and Findings In Experimental and Clinical Pharmacology, 30 :193-199. [DOI] [Details]
Khan, MAH,Sattar, MA,Abdullah, NA,Johns, EJ (2007) 'Cisplatin-induced nephrotoxicity causes altered renal hemodynamics in Wistar Kyoto and spontaneously hypertensive rats: Role of augmented renal alpha-adrenergic responsiveness'. Experimental and Toxicologic Pathology, 59 :253-260. [DOI] [Details]
Khan, AH,Sattar, MA,Abdullah, NA,Johns, EJ (2007) 'Influence of cisplatin-induced renal failure on the alpha(1)-adrenoceptor subtype causing vasoconstriction in the kidney of the rat'. European Journal of Pharmacology, 569 :110-118. [DOI] [Details]
Huang, CL,Yoshimoto, M,Miki, K,Johns, EJ (2006) 'The contribution of brain angiotensin II to the baroreflex regulation of renal sympathetic nerve activity in conscious normotensive and hypertensive rats'. Journal of Physiology-London, 574 :597-604. [DOI] [Details]
Bagnall, NM,Dent, PC,Walkowska, A,Sadowski, J,Johns, EJ (2005) 'Nitric oxide inhibition and the impact on renal nerve-mediated antinatriuresis and antidiuresis in the anaesthetized rat'. Journal of Physiology-London, 569 :849-856. [DOI] [Details]
Knight, S,Johns, EJ (2005) 'Effect of COX inhibitors and NO on renal hemodynamics following ischemia-reperfusion injury in normotensive and hypertensive rats'. The American journal of physiology, 289 :1072-1077. [DOI] [Details]
Nakamura, A,Imaizumi, A,Niimi, R,Yanagawa, Y,Kohsaka, T,Johns, EJ (2005) 'Adenoviral delivery of the beta(2)-adrenoceptor gene in sepsis: a subcutaneous approach in rat for kidney protection'. Science (New York, N.Y.), 109 :503-511. [DOI] [Details]
Walkowska, A,Badzynska, B,Kompanowska-Jezierska, E,Johns, EJ,Sadowski, J (2005) 'Effects of renal nerve stimulation on intrarenal blood flow in rats with intact or inactivated NO synthases'. Acta Physiologica, 183 :99-105. [Details]
Kiew, LV,Munavvar, AS,Law, CH,Azizan, AN,Nazarina, AR,Sidik, K,Johns, EJ (2004) 'Effect of antisense oligodeoxynucleotides for ICAM-1 on renal ischaemia-reperfusion injury in the anaesthetised rat'. Journal of Physiology-London, 557 :981-989. [DOI] [Details]
Nakamura, A,Imaizumi, A,Yanagawa, Y,Kohsaka, T,Johns, EJ (2004) 'beta(2)-adrenoceptor activation attenuates endotoxin-induced acute renal failure'. Journal of the American Society of Nephrology : JASN, 15 :316-325. [DOI] [Details]
Sabharwal, R,Coote, JH,Johns, EJ,Egginton, S (2004) 'Effect of hypothermia on baroreflex control of heart rate and renal sympathetic nerve activity in anaesthetized rats'. Journal of Physiology-London, 557 :247-259. [DOI] [Details]
Wu, XC,Johns, EJ (2004) 'Interactions between nitric oxide and superoxide on the neural regulation of proximal fluid reabsorption in hypertensive rats'. Experimental Physiology, 89 :255-261. [DOI] [Details]
Armenia, A,Munavvar, AS,Abdullah, NA,Helmi, A,Johns, EJ (2004) 'The contribution of adrenoceptor subtype(s) in the renal vasculature of diabetic spontaneously hypertensive rats'. British Journal of Pharmacology, 142 :719-726. [DOI] [Details]
Sabharwal, R,Johns, EJ,Egginton, S (2004) 'The influence of acute hypothermia on renal function of anaesthetized euthermic and acclimatized rats'. Experimental Physiology, 89 :455-463. [DOI] [Details]
Nakamura, A,Imaizumi, A,Yanagawa, Y,Niimi, R,Kohsaka, T,Johns, EJ (2003) 'beta 2-adrenoceptor activation inhibits Shiga toxin2-induced apoptosis of renal tubular epithelial cells'. Biochemical pharmacology, 66 :343-353. [DOI] [Details]
Wongmekiat, O,Johns, EJ (2003) 'Endothelin as a causative factor of blunted volume reflex in diabetic rats'. British Journal of Pharmacology, 138 :1403-1410. [DOI] [Details]
Moosavi, SMS,Johns, EJ (2003) 'The effect of isoprenaline infusion on renal renin and angiotensinogen gene expression in the anaesthetised rat'. Experimental Physiology, 88 :221-227. [Details]
Ajis, A,Bagnall, NM,Collis, MG,Johns, EJ (2003) 'Effect of endothelin antagonists on the renal haemodynamic and tubular responses to ischaemia-reperfusion injury in anaesthetised rats'. Experimental Physiology, 88 :483-490. [Details]
Wongmekiat, O,Johns, EJ (2003) 'Significance of endothelin on volume homeostasis in obese Zucker rats'. Clinical and Experimental Pharmacology and Physiology, 30 :702-708. [Details]
Nakamura, A,Johns, EJ,Imaizumi, A,Niimi, R,Yanagawa, Y,Kohsaka, T (2002) 'Role of angiotensin II-induced cAMP in mesangial TNF-alpha production'. Cytokine, 19 :47-51. [DOI] [Details]
Wu, XC,Johns, EJ (2002) 'Nitric oxide modulation of neurally induced proximal tubular fluid reabsorption in the rat'. Hypertension, 39 :790-793. [Details]
Johns, EJ (2002) 'The autonomic nervous system and pressure-natriuresis in cardiovascular-renal interactions in response to salt'. Clinical Autonomic Research, 12 :256-263. [DOI] [Details]
Huang, CL,Huang, CH,Hestin, D,Dent, PC,Barclay, P,Collis, M,Johns, EJ (2002) 'The effect of endothelin antagonists on renal ischaemia-reperfusion injury and the development of acute renal failure in the rat'. Nephrology Dialysis Transplantation, 17 :1578-1585. [Details]
Salman, IM; Sattar, MA; Abdullah, NA; Ameer, OZ; Hussain, FB; Hye Khan, MA; Yam, MF; Rathore, KR; Kazi, RN; Salman, HM; Johns, EJ (2010) 'Role of norepinephrine & angiotensin II in the neural control of renal sodium & water handling in spontaneously hypertensive rats'. The Indian journal of medical research, 131 :786-792. [Details]
Salman, IM; Ameer, OZ; Sattar, MA; Abdullah, NA; Yam, MF; Najim, HS; Abdulkarim, MF; Abdullah, GZ; Kaur, G; Khan, MA; Johns, EJ (2010) 'Characterization of renal hemodynamic and structural alterations in rat models of renal impairment: role of renal sympathoexcitation'. Journal of nephrology, . [Details]
Salman, IM; Sattar, MA; Abdullah, NA; Ameer, OZ; Hussain, FB; Hye Khan, MA; Yam, MF; Rathore, KR; Kazi, RN; Salman, HM; Johns, EJ (2010) 'Renal ischemic injury affects renal hemodynamics and excretory functions in Sprague Dawley rats: involvement of renal sympathetic tone'. Renal Failure, 32 (1):96-102. [DOI] [Details]
Salman, IM; Sattar, MA; Abdullah, NA; Ameer, OZ; Hussain, FB; Hye Khan, MA; Yam, MF; Rathore, KR; Kazi, RN; Salman, HM; Johns, EJ (2010) 'Renal functional & haemodynamic changes following acute unilateral renal denervation in Sprague Dawley rats'. The Indian journal of medical research, 131 :76-82. [Details]
Houghton, BL; Huang, C; Johns EJ (2010) 'Influence of dietary sodium on the blood pressure and renal sympathetic nerve activity responses to intracerebroventricular angiotensin II and angiotensin III in anaesthetized rats'. Experimental Physiology, 95 (2):282-295. [DOI] [Details]
Salman, IM; Ameer, OZ; Sattar, MA; Abdullah, NA; Yam, MF; Najim, HS; Abdulkarim, MF; Abdullah, GZ; Kaur, G; Khan, MA; Johns, EJ (2010) 'Role of the renal sympathetic nervous system in mediating renal ischaemic injury-induced reductions in renal haemodynamic and excretory functions'. Pathology, 42 (3):259-266. [DOI] [Details]
Johns, EJ; O'Shaughnessy, B; O'Neill, S; Lane, B; Healy, V (2010) 'Impact of elevated dietary sodium intake on NAD(P)H oxidase and SOD in the cortex and medulla of the rat kidney'. American Journal of Physiology-Regulatory Integrative and Comparative Physiology, 299 (1):1-40. [DOI] [Details]
Salman, IM; Sattar, MA; Abdullah, NA; Ameer, OZ; Basri, F; Hussain, NM; Yam, MF; Swarup, KR; Rathore, HA; Kazi, RN; Hye Khan, MA; Johns, EJ (2010) 'Role of renal sympathetic nervous system in the control of renal potassium handling'. Journal of nephrology, 23 (3):291-296. [Details]
Rathore, HA; Munavvar, AS; Abdullah, NA; Khan, AH; Fathihah, B; NurJannah, MH; Raisa, NA; Anand Swarup, KR; Abdullah, MH; Salman, IM; Johns, EJ (2009) 'Interaction between renin-angiotensin and sympathetic nervous systems in a rat model of pressure overload cardiac hypertrophy'. Autonomic & autacoid pharmacology, 29 (4):171-180. [DOI] [Details]
Khan MA, Sattar MA, Abdullah NA, Abdulla MH, Salman IM, Kazi RN, Swarup KR, Rathore HA, Basri F, Hussain NM, Dewa A, Johns EJ (2009) 'Functional subtypes of renal alpha1-adrenoceptor in spontaneously hypertensive rats with streptozotocin-induced experimental diabetic nephropathy'. Blood, 32 (5):349-359. [DOI] [Details]
Walsh SK, English FA, Johns EJ, Kenny LC (2009) 'Plasma-mediated vascular dysfunction in the reduced uterine perfusion pressure model of preeclampsia: a microvascular characterization'. Hypertension, 54 (2):345-351. [DOI] [Details]
Johns, EJ (2009) 'Inflammation: the underlying foe in renovascular hypertension?'. Journal of Hypertension, 27 (10):1964-1965. [DOI] [Details]
Abdulla MH, Sattar MA, Abdullah NA, Khan MA, Abdallah HH, Johns EJ (2009) 'Chronic treatment with losartan and carvedilol differentially modulates renal vascular responses to sympathomimetics compared to treatment with individual agents in normal Wistar Kyoto and spontaneously hypertensive rats'. European Journal of Pharmacology, 612 (1-3):69-74. [DOI] [Details]
Khan AH, Sattar MA, Abdullah NA, Johns EJ (2009) 'Effect of calcium channel blockade on adrenergically induced renal vasoconstriction in rat models of renal impairment'. Clinical and Experimental Pharmacology and Physiology, 36 (5-6):501-508. [DOI] [Details]
Abdulla MH, Sattar MA, Khan MA, Abdullah NA, Johns EJ (2009) 'Influence of sympathetic and AT-receptor blockade on angiotensin II and adrenergic agonist-induced renal vasoconstrictions in spontaneously hypertensive rats'. Acta Physiologica, 195 (3):397-404. [DOI] [Details]
Kazi RN, Munavvar AS, Abdullah NA, Khan AH, Johns EJ (2009) 'Influence of high dietary sodium intake on the functional subtypes of alpha-adrenoceptors in the renal cortical vasculature of Wistar-Kyoto rats'. Autonomic & autacoid pharmacology, 29 (1-2):25-31. [DOI] [Details]
Khan, AH, Sattar, MA, Abdullah, NA, Johns, EJ (2009) 'Effect of Calcium Channel Blockade On Adrenergically Induced Renal Vasoconstriction In Rat Models of Renal Impairment'. Clinical and Experimental Pharmacology and Physiology, 36 (5-6):501-508. [DOI] [Details]
Abdulla, MH, Sattar, MA, Khan, MAH, Abdullah, NA, Johns, EJ (2009) 'Influence of Sympathetic and At(1)-Receptor Blockade On Angiotensin Ii and Adrenergic Agonist-Induced Renal Vasoconstrictions In Spontaneously Hypertensive Rats'. Acta Physiologica, 195 (3):397-404. [DOI] [Details]
Salman, IM, Sattar, MA, Abdullah, NA, Ameer, OZ, Abdulla, MH, Khan, MAH, Johns, EJ (2009) 'Quantification of Acute Renal Denervation Diuresis and Natriuresis In Sprague Dawley and Spontaneously Hypertensive Rats'. International Journal of Pharmacology, 5 (1):30-36. [Details]
Walsh, SK, English, FA, Johns, EJ, Kenny, LC (2009) 'Plasma-Mediated Vascular Dysfunction In The Reduced Uterine Perfusion Pressure Model of Preeclampsia A Microvascular Characterization'. Hypertension, 54 (2):345-264. [DOI] [Details]
Abdulla, MH, Sattar, MA, Abdullah, NA, Khan, MAH, AbdAllah, HH, Johns, EJ (2009) 'Chronic Treatment With Losartan and Carvedilol Differentially Modulates Renal Vascular Responses to Sympathomimetics Compared to Treatment With Individual Agents In Normal Wistar Kyoto and Spontaneously Hypertensive Rats'. European Journal of Pharmacology, 612 (1-3):69-74. [DOI] [Details]
Salman, IM, Sattar, MA, Abdullah, NA, Ameer, OZ, Abdulla, MH, Basri, F, Hussain, NJM, Khan, MAH, Yam, MF, Swarup, KRLA, Rathore, HA, Kazi, RN, Sriramaneni, RN, Johns, EJ (2009) 'The Role of Renal Sympathetic Nerve Activity In Mediating Renal Hemodynamic Alterations In Rat Models of Renal Impairment'. Advances In Clinical and Experimental Medicine, 18 (3):205-214. [Details]
Hiong, LC, Voon, KL, Abdullah, NA, Sattar, MA, Rahman, NA, Khan, AH, Johns, EJ (2008) 'Effect of Tgf-Beta 1 Antisense Oligodeoxynucleotide On Renal Function In Chronic Renal Failure Rats'. Acta Pharmacologica Sinica, 29 (4):451-457. [DOI] [Details]
Kompanowska-Jezierska, E, Wolff, H, Kuczeriszka, M, Gramsbergen, JB, Walkowska, A, Johns, EJ, Bie, P (2008) 'Renal Nerves and Nnos: Roles In Natriuresis of Acute Isovolumetric Sodium Loading In Conscious Rats'. American Journal of Physiology-Regulatory Integrative and Comparative Physiology, 294 (4):1130-1139. [DOI] [Details]
Flanagan, ET, Buckley, MM, Aherne, CM, Lainis, F, Sattar, M, Johns, EJ (2008) 'Impact of Cardiac Hypertrophy On Arterial and Cardiopulmonary Baroreflex Control of Renal Sympathetic Nerve Activity In Anaesthetized Rats'. Experimental Physiology, 93 (9):1058-1064. [DOI] [Details]
Lazahari, MIA, Sattar, MA, Abdullah, NA, Khan, MAH, Johns, EJ (2008) 'Clonidine and A Novel Clonidine Analog Al-12 Cause Sympathoinhibition In Spontaneously Hypertensive and Diabetic Spontaneously Hypertensive Rats'. Methods and Findings In Experimental and Clinical Pharmacology, 30 (3):193-199. [DOI] [Details]
Khan, MAH, Sattar, MA, Abdullah, NA, Johns, EJ (2008) 'Influence of Combined Hypertension and Renal Failure On Functional Alpha(1)-Adrenoceptor Subtypes In The Rat Kidney'. British Journal of Pharmacology, 153 (6):1232-1241. [DOI] [Details]
Armenia, A, Sattar, MA, Abdullah, NA, Khan, MAH, Johns, EJ (2008) 'Functional Subtypes of Renal Alpha(1)-Adrenoceptor In Diabetic and Non-Diabetic 2k1c Goldblatt Renovascular Hypertension'. Acta Pharmacologica Sinica, 29 (5):564-572. [DOI] [Details]
Knight, S, Johns, EJ (2008) 'Renal Functional Responses to Ischaemia-Reperfusion Injury In Normotensive and Hypertensive Rats Following Non-Selective and Selective Cyclo-Oxygenase Inhibition With Nitric Oxide Donation'. Clinical and Experimental Pharmacology and Physiology, 35 (1):11-16. [Details]
Li, YT, Qiu, JH, Zhuo, Y, Johns, EJ, Tao, Z (2008) 'Long-Range Correlation of Renal Sympathetic Nerve Activity In Both Conscious and Anesthetized Rats'. Journal of Neuroscience Methods, 172 (1):131-136. [DOI] [Details]
Khan, MAH, Sattar, MA, Abdullah, NA, Johns, EJ (2008) 'Alpha(1b)-Adrenoceptors Mediate Adrenergically-Induced Renal Vasoconstrictions In Rats With Renal Impairment'. Acta Pharmacologica Sinica, 29 (2):193-203. [DOI] [Details]
Khan, MAH, Sattar, MA, Abdullah, NA, Johns, EJ (2007) 'Cisplatin-Induced Nephrotoxicity Causes Altered Renal Hemodynamics In Wistar Kyoto and Spontaneously Hypertensive Rats: Role of Augmented Renal Alpha-Adrenergic Responsiveness'. Experimental and Toxicologic Pathology, 59 (3-4):253-260. [DOI] [Details]
Khan, AH, Sattar, MA, Abdullah, NA, Johns, EJ (2007) 'Influence of Cisplatin-Induced Renal Failure On The Alpha(1)-Adrenoceptor Subtype Causing Vasoconstriction In The Kidney of The Rat'. European Journal of Pharmacology, 569 (1-2):110-118. [DOI] [Details]
Armenia A, Munavvar AS, Abdullah NA, Helmi A, Johns EJ (2004) 'The contribution of adrenoceptor subtype(s) in the renal vasculature of diabetic spontaneously hypertensive rats'. British Journal of Pharmacology, 142 (4):719-716. [Details]
Wu XC, Johns EJ (2004) 'Interactions between nitric oxide and superoxide on the neural regulation of proximal fluid reabsorption in hypertensive rats'. Experimental Physiology, 89 (3):255-261. [Details]
Sabharwal R, Coote JH, Johns EJ, Egginton S (2004) 'Effect of hypothermia on baroreflex control of heart rate and renal sympathetic nerve activity in anaesthetized rats'. Journal of Physiology, 557 ((Pt 1)):247-259. [Details]
Kiew LV, Munavvar AS, Law CH, Azizan AN, Nazarina AR, Sidik K, Johns EJ. (2004) 'Effect of antisense oligodeoxynucleotides for ICAM-1 on renal ischaemia-reperfusion injury in the anaesthetised rat'. Journal of Physiology, 557 ((Pt 3)):981-989. [Details]
Gaffney R, Johns EJ. (2004) 'Acute intracerebroventricular (icv) leptin administration and the baroreflex control of renal sympathetic nerve activity (RSNA) in the anaesthetized rat'. Journal of Physiology, 560P . [Details]
Johns EJ (2004) 'Smoking is bad for you: our genes say so!'. Journal of Hypertension, 22 (2):245-246. [Details]
Sabharwal R, Johns EJ, Egginton S (2004) 'The influence of acute hypothermia on renal function of anaesthetized euthermic and acclimatized rats'. Experimental Physiology, 89 ((4)):455-463. [Details]
Ajis A, Bagnall NM, Collis MG, Johns EJ (2003) 'Effect of endothelin antagonists on the renal haemodynamic and tubular responses to ischaemia-reperfusion injury in anaesthetised rats'. Experimental Physiology, 88 ((4)):483-490. [Details]
Johns EJ (2003) 'Genes, gender and blood pressure regulation'. Journal of Hypertension, 21 ((8)):1447-1448. [Details]
Nakamura A, Imaizumi A, Yanagawa Y, Niimi R, Kohsaka T, Johns EJ. (2003) 'Beta2-adrenoceptor activation inhibits Shiga toxin2-induced apoptosis of renal tubular epithelial cells'. Biochemical pharmacology, 66 ((2)):343-353. [Details]
Wongmekiat O, Johns EJ. (2003) 'Endothelin as a causative factor of blunted volume reflex in diabetic rats'. British Journal of Pharmacology, 138 ((8)):1403-1410. [Details]
Moosavi SM, Johns EJ (2003) 'The effect of isoprenaline infusion on renal renin and angiotensinogen gene expression in the anaesthetised rat'. Experimental Physiology, 88 ((2)):221-227. [Details]
Nakamura A, Johns EJ, Imaizumi A, Niimi R, Yanagawa Y, Kohsaka T. (2002) 'Role of angiotensin II-induced cAMP in mesangial TNF-alpha production'. Cytokine, 19 ((1)):47-51. [Details]
Mustafa MR, Johns EJ (2001) 'The role of haem oxygenase in renal vascular reactivity in normotensive and hypertensive rats'. Journal of Hypertension, 19 ((6)):1105-1111. [Details]
Wongmekiat O, Johns EJ. (2001) 'Interactions between nitric oxide and renal nerves in the excretion of a saline load in obese Zucker rats'. Clinical Science, 101 ((3)):275-283. [Details]
Kompanowska-Jezierska E, Walkowska A, Johns EJ, Sadowski J. (2001) 'Early effects of renal denervation in the anaesthetised rat: natriuresis and increased cortical blood flow'. Journal of Physiology, 531 ((Pt2)):527-534. [Details]
 

Conference Publications

O'Neill, J; Johns,E (2010) Impact of dietary sodium on the renal haemodynamic and excretory responses to Angiotensin 1-7 in anaesthetised Rats Physiological Society General Meeting Manchester, , 01-JUL-10 - 03-JUL-10 [Details]
Barseem, H; Johns EJ (2010) Contribution of angiotensin AT2 receptors to the baroreflex control of renal sympathetic nerve activity in anaesthetised rats Physiological Society Meeting Manchester, , 01-JUL-10 - 03-JUL-10 [Details]
Buckley, M Brennan, D and Johns, E (2009) Renal excretory responses to a volume load in conscious Wistar rats with heart hypertrophy Physiological Society General Meeting Dublin, , 01-JUL-09 - 04-JUL-09 [Details]
JohnsE and Albulushi, A (2009) Impact of Angiotensin 1-7 (Ang1-7) on renal haemodynamic and excretory function anaesthetised normotensive and hypertensive rats Physiological Society General Meeting Dublin, , 01-JUL-09 - 04-JUL-09 [Details]
Ahameda, A, O'Reilly, E and JohnsEJ (2009) Regulation of renal haemodynamics by reactive oxygen species in anaesthetised rats: a direct or indirect action via nitric oxide? Physiological Society General Meeting Dublin, , 01-JUL-09 - 04-JUL-09 [Details]
Lainis, F, Buckley, M and Johns, E. (2009) Thyroxine induced heart hypertrophy: impact on cardiac function Physiological Society Meeting Dublin, , 01-JUL-09 - 04-JUL-09 [Details]
Margham, Y and Johns, E (2009) Impact of reactive oxygen species on renal function in anaesthetised rats Physiological Society General Meeting Dublin, , 01-JUL-09 - 04-JUL-09 [Details]
Corbett, A and Johns, E (2009) he impact of a low sodium diet on the renal functional responses to angiotension 1-7 (Ang1-7) in anaesthetised rats Physiological Society General Meeting Dublin, , 01-JUL-09 - 04-JUL-09 [Details]
Flanagan, E and Johns, EJ (2008) siRNA modulation of TGF-β: impact in a rat model of chronic renal failure Physiological Society General meeting Bristol, , 17-MAR-08 - 19-MAR-08 [Details]
Johns, E, O¿Shaugnessy B, O¿Neill S, Lane B and HealyV (2008) High dietary sodium intake - an oxidative strress for the kidney? Physiological Society General Meeting Bristol, , 17-MAR-08 - 19-MAR-08 [Details]
Gaffney R, Johns EJ. (2004) Intracerebroventricular (icv) leptin administration blunts baroreflex control of renal sympathetic nerve activity (RSNA) in anaesthetized rats The BioSciences Institute Postgraduate Seminar Series UCC, , 01-JAN-04 - 01-JAN-04 [Details]
Gaffney R, Johns EJ. (2003) Intracerebroventricular (icv) leptin administration blunts baroreflex control of renal sympathetic nerve activity (RSNA) in anaesthetized rats The Royal Academy of Medicine Ireland (RAMI) Meeting UCC, , 01-JAN-03 - 01-JAN-03 [Details]
Gaffney R, Johns EJ. (2003) Intracerebroventricular (icv) leptin administration blunts baroreflex control of renal sympathetic nerve activity (RSNA) in anaesthetized rats The 11th Annual Research Day for the Faculty of Medicine and Health UCC, , 01-JAN-03 - 01-JAN-03 [Details]
Ahmeda, Ahmad F; Johns, Edward J (2006) Influence of superoxide anions in the neural control of intra-renal haemodynamics of anaesthetised normotensive and hypertensive rats unknown: Proc Physiol Soc 3: PC19 [Details]
Ahmeda, Ahmad F; Johns, Edward J (2005) Role of nitric oxide in neural control of intra-renal homodynamic in anaesthetised normotensive and hypertensive rats unknown: J Physiol 567P: C104 [Details]
Ahmeda, Ahmad F; Johns, Edward J (2004) Role of oxidative stress on the renal microvasculature of anaesthetised wistar and stroke prone spontaneously hypertensive rats (SHRSP) unknown: J Physiol 560P: C3 [Details]
                                       
Image Denoting Logos of Sites to which this page can be shared