Research Profile

Mohammed Abdulla

Biography

Mohammed Abdulla graduated with a 1st Class BSc (Pharmacy) degree from the College of Pharmacy, University of Baghdad, Iraq in 2001. He obtained an MSc degree in Pharmacology in 2009 and then a PhD degree in Physiology in 2012 from the University of Science Malaysia in Penang, Malaysia. In 2011, Mohammed joined Edward J. Johns’s renal Physiology lab in Cork, Ireland as a Wellcome trust post-doctoral researcher investigating the role of brain angiotensin II (type 2) receptors and nitric oxide in the baroreflex control of renal sympathetic nerve activity. In November 2014, he was recruited to University College Cork (UCC) as Lecturer in Physiology, where he leads his own independent research group focusing on innervation of the kidney in renal injury and inflammation as a cause of deranged cardiovascular control. He obtained a master’s degree in teaching and learning in higher education in UCC in February 2019. Mohammed is the recipient of multiple research awards and travel grants. He is the recent recipient of the Translational Research Access Programme grant in UCC. His activities in research have generated more than 30 peer-reviewed journal articles and reviews to date.  

Research Interests

The main interest of research has been towards gaining a greater understanding of the neural control of the kidney in terms of renal haemodynamic and excretory function. This has involved a careful analysis at the key regulatory role played by renal sympathetic nerves. The initial studies during my Master and PhD studies was to explore the functional contribution of alpha 1 adrenoceptor subtypes and angiotensin II receptors in pathophysiological states, with specific regard to hypertension, diabetes, heart failure, chronic and acute renal failure and diet-induced metabolic syndrome. This theme has continued in my postdoctoral work where studies are being extended to determine the interactions between the renin-angiotensin and nitric oxide systems in the brain to regulate the sympathetic nervous system in anaesthetized and conscious rat models of various cardiovascular diseases. There has been also an attempt to further investigate the mechanism of oxidative stress and its correlation with insulin resistance syndrome. More recently, I have developed a major interest in the afferent sensory nerves in the injured or diseased kidney and the role played by inflammatory mediators such as bradykinin and its receptors as well cross talk with TRPV1 receptors.


Supervised projects:

1. Role of Bradykinin receptors in the baroreflex mechanism in renal failure/injury (Final year research supervision, the project was supported by the Department of Physology, University College Cork) 2015.

2. Investigation of the interaction between central nitric oxide system and angiotensin II (type II) receptors (AT2)-mediated baroreflex control of renal sympathetic nerve activity (project supported by the Wellcome Trust) 2011-2014.

3. The impact of TRPV1 channels antagonism on the baroreflex control of renal sympathetic nerve activity in renal failure rat model (Final year research supervision, the project was supported by the Department of Physiology, University College Cork) 2013.

4. Bradyzide, a B2 receptor antagonist, restores the renal sympatho-inhibition reflex in cisplatin-induced renal failure of anaesthetized male Wistar rats (Molecular Medicine Ireland Ph.D student’s lab placement research co-supervision) 2012.

5. Bradykinin B2 receptor antagonism restores the low-pressure baroreflex mechanism in cisplatin-induced renal failure rats (Student’s summer research co-supervision, the project was supported by the Wellcome trust) 2012.



Research Grants

 ProjectFunding
Body
Start DateEnd DateAward
Gut Dysbiosis and CKD: Cause or Consequence?UCC TRAP (Translational Research Access Programme)01-NOV-1801-NOV-19€10,000.00
The effects of TRPV1 receptor blockade on the renal functional response to volume expansion in chronic intermittent hypoxia rat modelOther: Not Listed01-JUN-1801-AUG-18€500.00
The effects of TRPV1 receptor blockade on the renal functional response to volume expansion in chronic intermittent hypoxia rat modelOther: Not Listed01-JUN-1801-AUG-18€2,000.00

Contract Researchers

 Researcher NameProjectRoleFunding Body
Dr Jennifer ManningInvestigation of the interaction between central nitric oxide system and angiotensin II (type II) receptors (AT2)-mediated baroreflex control of renal sympathetic nerve activityPostdoctoral ResearcherWellcome Trust

Publications

Book Chapters

 YearPublication
(2021)'Autonomic regulation of kidney function'
Mohammed H. Abdulla and Edward J. Johns (2021) 'Autonomic regulation of kidney function' In: The Oxford Encyclopedia of Neuroendocrine and Autonomic Systems. UK: Oxford University Press. [Details]

Peer Reviewed Journals

 YearPublication
(2023)'An investigation of pre-clinical medical students’ preference for summative or formative assessment for physiology learning'
Mohammed H. Abdulla, Mark G. Rae (2023) 'An investigation of pre-clinical medical students’ preference for summative or formative assessment for physiology learning'. Advances in Physiology Education, - (-):---   [DOI] [Details]
(2022)'Correspondence: Renal denervation for atrial fibrillation: a comprehensive updated systematic review and meta-analysis'
Nawar K;Mohammad A;Johns EJ;Abdulla MH; (2022) 'Correspondence: Renal denervation for atrial fibrillation: a comprehensive updated systematic review and meta-analysis'. Journal of human hypertension, [DOI] [Details]
(2022)'Effects of intrarenal angiotensin 1-7 infusion on renal haemodynamic and excretory function in anaesthetised two-kidney one-clip and deoxycorticosterone acetate-salt hypertensive rats'
Barry, EF;Abdulla, MH;O'Neill, J;AlMarabeh, S;Beshara, J;Parna-Gile, E;Johns, EJ (2022) 'Effects of intrarenal angiotensin 1-7 infusion on renal haemodynamic and excretory function in anaesthetised two-kidney one-clip and deoxycorticosterone acetate-salt hypertensive rats'. Experimental Physiology, [DOI] [Details]
(2022)'Intrarenal pelvic bradykinin-induced sympathoexcitatory reno-renal reflex is attenuated in rats exposed to chronic intermittent hypoxia'
AlMarabeh, S;Lucking, EF;O'Halloran, KD;Abdulla, MH (2022) 'Intrarenal pelvic bradykinin-induced sympathoexcitatory reno-renal reflex is attenuated in rats exposed to chronic intermittent hypoxia'. Journal of Hypertension, 40 :46-64 [DOI] [Details]
(2021)'Exposure to High-Fat Style Diet Induced Renal and Liver Structural Changes, Lipid Accumulation and Inflammation in Intact and Ovariectomized Female Rats'
Sucedaram Y;Johns EJ;Husain R;Abdul Sattar M;H Abdulla M;Nelli G;Rahim NS;Khalilpourfarshbafi M;Abdullah NA; (2021) 'Exposure to High-Fat Style Diet Induced Renal and Liver Structural Changes, Lipid Accumulation and Inflammation in Intact and Ovariectomized Female Rats'. Inflammation Research, 14 [DOI] [Details]
(2021)'The renal excretory responses to acute renal interstitial angiotensin (1-7) infusion in anaesthetised spontaneously hypertensive rats'
Barry, EF;O'Neill, J;Abdulla, MH;Johns, EJ (2021) 'The renal excretory responses to acute renal interstitial angiotensin (1-7) infusion in anaesthetised spontaneously hypertensive rats'. Clinical and experimental pharmacology & physiology, 48 :1674-1684 [DOI] [Details]
(2021)'The differential modulation of the baroreflex control mechanism in fight, flight or freeze behaviour'
AlMarabeh S;Abdulla MH; (2021) 'The differential modulation of the baroreflex control mechanism in fight, flight or freeze behaviour'. Experimental Physiology, 106 (12) [DOI] [Details]
(2021)'A Narrative Review on the Phytochemistry, Pharmacology and Therapeutic Potentials of Clinacanthus nutans (Burm. f.) Lindau Leaves as an Alternative Source of Future Medicine'
Chia TY;Gan CY;Murugaiyah V;Hashmi SF;Fatima T;Ibrahim L;Abdulla MH;Alswailmi FK;Johns EJ;Ahmad A; (2021) 'A Narrative Review on the Phytochemistry, Pharmacology and Therapeutic Potentials of Clinacanthus nutans (Burm. f.) Lindau Leaves as an Alternative Source of Future Medicine'. Molecules (Basel, Switzerland), 27 (1) [DOI] [Details]
(2020)'Comparison of high-fat style diet-induced dysregulation of baroreflex control of renal sympathetic nerve activity in intact and ovariectomized female rats: Renal sympathetic nerve activity in high-fat style diet fed intact and ovariectomized female rats'
Sucedaram Y.;Johns E.J.;Husain R.;Sattar M.A.;Abdulla M.;Khalilpourfarshbafi M.;Abdullah N.A. (2020) 'Comparison of high-fat style diet-induced dysregulation of baroreflex control of renal sympathetic nerve activity in intact and ovariectomized female rats: Renal sympathetic nerve activity in high-fat style diet fed intact and ovariectomized female rats'. Experimental Biology and Medicine, [DOI] [Details]
(2020)'Chronic intermittent hypoxia impairs diuretic and natriuretic responses to volume expansion in rats with preserved low-pressure baroreflex control of the kidney'
AlMarabeh, Sara ; O'Neill, Julie; Cavers, Jeremy; Lucking, Eric F.; O'Halloran, Ken D.; Abdulla, Mohammed H. (2020) 'Chronic intermittent hypoxia impairs diuretic and natriuretic responses to volume expansion in rats with preserved low-pressure baroreflex control of the kidney'. American journal of physiology. Renal physiology, [DOI] [Full Text] [Details]
(2020)'Effects of intracerebroventricular leptin and orexin-A on the baroreflex control of renal sympathetic nerve activity in conscious rats fed a normal or high-fat diet'
Huang, Chunlong; AlMarabeh, Sara; Cavers, Jeremy; Abdulla, Mohammed H.; Johns, Edward J. (2020) 'Effects of intracerebroventricular leptin and orexin-A on the baroreflex control of renal sympathetic nerve activity in conscious rats fed a normal or high-fat diet'. Clinical and experimental pharmacology & physiology, [DOI] [Full Text] [Details]
(2020)'Apocynin and catalase prevent hypertension and kidney injury in Cyclosporine A-induced nephrotoxicity in rats'
Tan Y.C.;Sattar M.A.;Ahmeda A.F.;Khan N.A.K.;Murugaiyah V.;Ahmad A.;Hassan Z.;Kaur G.;Abdulla M.H.;Johns E.J. (2020) 'Apocynin and catalase prevent hypertension and kidney injury in Cyclosporine A-induced nephrotoxicity in rats'. Plos One, 15 (4) [DOI] [Details]
(2020)'The Restorative Effect of Apocynin and Catalase in L-Arginine-Induced Hypotension on Normotensive Subjects - the Role of Oxidative Stress'
Chia, TY;Murugaiyah, V;Sattar, MA;Karim Khan, NA;Ahmad, A;Abdulla, MH;Johns, EJ;Mei, HY;Akhtar, S;Ahmad, FU (2020) 'The Restorative Effect of Apocynin and Catalase in L-Arginine-Induced Hypotension on Normotensive Subjects - the Role of Oxidative Stress'. Physiological Research, 69 :1051-1066 [DOI] [Details]
(2020)'Unraveling the Role of Interleukin-11 in Renal and Cardiac Fibrosis in Malignant Hypertension'
Abdulla M.H.;O'Halloran K.D. (2020) 'Unraveling the Role of Interleukin-11 in Renal and Cardiac Fibrosis in Malignant Hypertension'. American Journal of Hypertension, 33 (4):303-304 [DOI] [Details]
(2020)'Apocynin and catalase prevent hypertension and kidney injury in Cyclosporine A-induced nephrotoxicity in rats'
Tan YC, Abdul Sattar M, Ahmeda AF, Abdul Karim Khan N, Murugaiyah V, Ahmad A, Hassan Z, Kaur G, Abdulla MH, Johns EJ (2020) 'Apocynin and catalase prevent hypertension and kidney injury in Cyclosporine A-induced nephrotoxicity in rats'. Plos One, 15 (4) [DOI] [Details]
(2019)'Tacrolimus restores the high- and low-pressure baroreflex control of renal sympathetic nerve activity in cisplatin-induced renal injury rats'
Abdulla M.;Brennan N.;Ryan E.;Sweeney L.;Manning J.;Johns E. (2019) 'Tacrolimus restores the high- and low-pressure baroreflex control of renal sympathetic nerve activity in cisplatin-induced renal injury rats'. Experimental Physiology, 104 (11):1726-1736 [DOI] [Details]
(2019)'Brainstem adrenomedullin facilitates intermittent hypoxia-induced hypertension: A sympathetic story of a selfish brain'
Abdulla M.;O'Halloran K. (2019) 'Brainstem adrenomedullin facilitates intermittent hypoxia-induced hypertension: A sympathetic story of a selfish brain'. Experimental Physiology, 104 (11):1589-1590 [DOI] [Details]
(2019)'Is Aberrant Reno-Renal Reflex Control of Blood Pressure a Contributor to Chronic Intermittent Hypoxia-Induced Hypertension?'
AlMarabeh S;Abdulla MH;O'Halloran KD; (2019) 'Is Aberrant Reno-Renal Reflex Control of Blood Pressure a Contributor to Chronic Intermittent Hypoxia-Induced Hypertension?'. Frontiers in Physiology, 10 [DOI] [Details]
(2019)'The impact of supplementing PowerPoint with detailed notes and explanatory videos on student attendance and performance in a Physiology module in medicine'
Mohammed H. Abdulla and Eleanor O'Sullivan (2019) 'The impact of supplementing PowerPoint with detailed notes and explanatory videos on student attendance and performance in a Physiology module in medicine'. Medical Science Educator, [DOI] [Details]
(2019)'Renal cortical oxygen tension is decreased following exposure to long-term but not short-term intermittent hypoxia in the rat'
O'Neill, Julie; Jasionek, Greg; Drummond, Sarah E.; Brett, Orla; Lucking, Eric F.; Abdulla, Mohammed A.; O'Halloran, Ken D. (2019) 'Renal cortical oxygen tension is decreased following exposure to long-term but not short-term intermittent hypoxia in the rat'. American Journal of Physiology (Renal),   [DOI] [Full Text] [Details]
(2018)'The use of an online student response system to support learning of Physiology during lectures to medical students'
Abdulla, MH (2018) 'The use of an online student response system to support learning of Physiology during lectures to medical students'. Education and Information Technologies, 23 :2931-2946 [DOI] [Details]
(2017)'The role of brain angiotensin II (type 2) receptors and nitric oxide in the renal sympathoinhibitory response to acute volume expansion in conscious rats'
Abdulla, MH;Johns, EJ (2017) 'The role of brain angiotensin II (type 2) receptors and nitric oxide in the renal sympathoinhibitory response to acute volume expansion in conscious rats'. Journal of Hypertension, 35 :338-347 [DOI] [Details]
(2016)'Bradykinin receptor blockade restores the baroreflex control of renal sympathetic nerve activity in cisplatin-induced renal failure rats'
Abdulla MH;Duff M;Swanton H;Johns EJ; (2016) 'Bradykinin receptor blockade restores the baroreflex control of renal sympathetic nerve activity in cisplatin-induced renal failure rats'. Acta Physiologica, [DOI] [Details]
(2017)'The innervation of the kidney in renal injury and inflammation: a cause and consequence of deranged cardiovascular control'
Abdulla MH, Johns EJ. (2017) 'The innervation of the kidney in renal injury and inflammation: a cause and consequence of deranged cardiovascular control'. Acta Physiologica,   [DOI] [Details]
(2017)'Improvement in baroreflex control of renal sympathetic nerve activity in obese Sprague-Dawley rats following immunosuppression'
Khan SA, Sattar MZA, Abdullah NA, Rathore HA, Ahmad A, Abdulla MH, Johns EJ. (2017) 'Improvement in baroreflex control of renal sympathetic nerve activity in obese Sprague-Dawley rats following immunosuppression'. Acta Physiologica,   [DOI] [Details]
(2017)'Assessment of renal function in the anaesthetised rat following injection of superparamagnetic iron oxide nanoparticles'
Edge D, Shortt CM, Johns EJ, Gobbo OL, Markos F, Abdulla MH, Barry EF. (2017) 'Assessment of renal function in the anaesthetised rat following injection of superparamagnetic iron oxide nanoparticles'. Canadian Journal of Physiology and Pharmacology, 95 (4):443-446 [DOI] [Details]
(2016)'Up Regulation of cystathione gamma lyase and Hydrogen Sulphide in the Myocardium Inhibits the Progression of Isoproterenol-Caffeine Induced Left Ventricular Hypertrophy in Wistar Kyoto Rats'
Ahmad, A;Sattar, MA;Rathore, HA;Abdulla, MH;Khan, SA;Azam, M;Abdullah, NA;Johns, EJ (2016) 'Up Regulation of cystathione gamma lyase and Hydrogen Sulphide in the Myocardium Inhibits the Progression of Isoproterenol-Caffeine Induced Left Ventricular Hypertrophy in Wistar Kyoto Rats'. Plos One, 11 [DOI] [Details]
(2016)'Effects of tempol on altered metabolism and renal vascular responsiveness in fructose-fed rats'
Abdulla MH, Sattar MA;Johns EJ (2016) 'Effects of tempol on altered metabolism and renal vascular responsiveness in fructose-fed rats'. Applied physiology, nutrition, and metabolism = Physiologie applique¿¿e, nutrition et me¿¿tabolisme, 41 (2):210-218 [DOI] [Details]
(2016)'Cystathione gamma lyase/Hydrogen Sulphide Pathway Up Regulation Enhances the Responsiveness of alpha 1A and alpha 1B-Adrenoreceptors in the Kidney of Rats with Left Ventricular Hypertrophy'
Ahmad, A;Sattar, MA;Azam, M;Abdulla, MH;Khan, SA;Hashmi, F;Abdullah, NA;Johns, EJ (2016) 'Cystathione gamma lyase/Hydrogen Sulphide Pathway Up Regulation Enhances the Responsiveness of alpha 1A and alpha 1B-Adrenoreceptors in the Kidney of Rats with Left Ventricular Hypertrophy'. Plos One, 11 [DOI] [Details]
(2016)'Enhanced expression of endothelial nitric oxide synthase in the myocardium ameliorates the progression of left ventricular hypertrophy in L-arginine treated Wistar-Kyoto rats'
Ahmad A;Sattar MA;Rathore HA;Abdulla MH;Khan SA;Abdullah NA;Johns EJ; (2016) 'Enhanced expression of endothelial nitric oxide synthase in the myocardium ameliorates the progression of left ventricular hypertrophy in L-arginine treated Wistar-Kyoto rats'. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 67 (1) [Details]
(2016)'Interaction between irbesartan, peroxisome proliferator-activated receptor (PPAR-¿), and adiponectin in the regulation of blood pressure and renal function in spontaneously hypertensive rats'
Afzal S;Sattar MA;Johns EJ;Abdulla MH;Akhtar S;Hashmi F;Abdullah NA; (2016) 'Interaction between irbesartan, peroxisome proliferator-activated receptor (PPAR-¿), and adiponectin in the regulation of blood pressure and renal function in spontaneously hypertensive rats'. Journal Of Physiology And Biochemistry, [DOI] [Details]
(2015)'Obesity depresses baroreflex control of renal sympathetic nerve activity and heart rate in Sprague Dawley rats: role of the renal innervation'
Khan SA, Sattar MZ, Abdullah NA, Rathore HA, Abdulla MH, Ahmad A, Johns EJ (2015) 'Obesity depresses baroreflex control of renal sympathetic nerve activity and heart rate in Sprague Dawley rats: role of the renal innervation'. Acta Physiologica, [DOI] [Details]
(2014)'Nitric oxide impacts on angiotensin AT2 receptor modulation of high-pressure baroreflex control of renal sympathetic nerve activity in anaesthetized rats'
Abdulla MH, Johns EJ (2014) 'Nitric oxide impacts on angiotensin AT2 receptor modulation of high-pressure baroreflex control of renal sympathetic nerve activity in anaesthetized rats'. Acta Physiologica, 210 (4):832-844 [Details]
(2014)'Functional contribution of α1D-adrenoceptors in the renal vasculature of left ventricular hypertrophy induced with isoprenaline and caffeine in Wistar-Kyoto rats'
Ahmad A, Sattar MA, Rathore HA, Abdulla MH, Khan SA, Abdullah NA, Kaur G, Johns EJ. (2014) 'Functional contribution of α1D-adrenoceptors in the renal vasculature of left ventricular hypertrophy induced with isoprenaline and caffeine in Wistar-Kyoto rats'. Canadian Journal of Physiology and Pharmacology, 92 (12):1029-1035   [Details]
(2013)'Blunted endogenous GABA-mediated inhibition in the hypothalamic paraventricular nucleus of rats with streptozotocin-induced diabetes'
Hassan Z, Sattar MZ, Suhaimi FW, Yusoff NH, Abdulla MH, Yusof AP, Johns EJ. (2013) 'Blunted endogenous GABA-mediated inhibition in the hypothalamic paraventricular nucleus of rats with streptozotocin-induced diabetes'. Acta Neurologica Belgica, 113 (3):319-225   [Details]
(2009)'Functional subtypes of renal alpha1-adrenoceptor in spontaneously hypertensive rats with streptozotocin-induced experimental diabetic nephropathy'
Khan MA, Sattar MA, Abdullah NA, Abdulla MH, Salman IM, Kazi RN, Swarup KR, Rathore HA, Basri F, Hussain NM, Dewa A, Johns EJ; (2009) 'Functional subtypes of renal alpha1-adrenoceptor in spontaneously hypertensive rats with streptozotocin-induced experimental diabetic nephropathy'. Blood, 32 (5):349-359 [DOI] [Details]
(2009)'Interaction between renin-angiotensin and sympathetic nervous systems in a rat model of pressure overload cardiac hypertrophy'
Rathore HA, Munavvar AS, Abdullah NA, Khan AH, Fathihah B, NurJannah MH, Raisa NA, Anand Swarup KR, Abdullah MH, Salman IM, Johns EJ. (2009) 'Interaction between renin-angiotensin and sympathetic nervous systems in a rat model of pressure overload cardiac hypertrophy'. Autonomic & Autacoid Pharmacology, 29 (4):171-180   [Details]
(2014)'Renal denervation restores the baroreflex control of renal sympathetic nerve activity and heart rate in Wistar-Kyoto rats with cisplatin-induced renal failure'
Khan SA, Sattar MA, Rathore HA, Abdulla MH, Ud Din Ahmad F, Ahmad A, Afzal S, Abdullah NA, Johns EJ. (2014) 'Renal denervation restores the baroreflex control of renal sympathetic nerve activity and heart rate in Wistar-Kyoto rats with cisplatin-induced renal failure'. Acta Physiologica, 210 (3):690-700 [Details]
(2013)'Role of angiotensin AT2 receptors and nitric oxide in the cardiopulmonary baroreflex control of renal sympathetic nerve activity in rats'
Abdulla MH, Johns EJ (2013) 'Role of angiotensin AT2 receptors and nitric oxide in the cardiopulmonary baroreflex control of renal sympathetic nerve activity in rats'. Journal of Hypertension, 31 (9):1837-1846 [Details]
(2013)'Renal nerves in blood pressure regulation'
Johns EJ, Abdulla MH (2013) 'Renal nerves in blood pressure regulation'. Current Opinion In Nephrology And Hypertension, 22 (5):504-510 [Details]
(2013)'The effects of tempol on renal function and hemodynamics in cyclosporine-induced renal insufficiency rats'
Chia TY, Sattar MA, Abdulla MH, Rathore HA, Ahmad Fu, Kaur G, Abdullah NA, Johns EJ. (2013) 'The effects of tempol on renal function and hemodynamics in cyclosporine-induced renal insufficiency rats'. Renal Failure, 35 (7):978-988 [Details]
(2012)'The effect of losartan and carvedilol on renal haemodynamics and altered metabolism in fructose-fed Sprague-Dawley rats'
Abdulla MH, Sattar MA, Abdullah NA, Johns EJ. (2012) 'The effect of losartan and carvedilol on renal haemodynamics and altered metabolism in fructose-fed Sprague-Dawley rats'. Journal Of Physiology And Biochemistry, 68 (3):353-363 [Details]
(2012)'High-fructose feeding impacts on the adrenergic control of renal haemodynamics in the rat'
Abdulla MH, Sattar MA, Johns EJ, Abdullah NA, Hye Khan MA, Rathore HA. (2012) 'High-fructose feeding impacts on the adrenergic control of renal haemodynamics in the rat'. British Journal of Nutrition, 107 (2):218-228 [Details]
(2012)'Exogenous hydrogen sulfide (H2S) reduces blood pressure and prevents the progression of diabetic nephropathy in spontaneously hypertensive rats'
Ahmad FU, Sattar MA, Rathore HA, Abdullah MH, Tan S, Abdullah NA, Johns EJ. (2012) 'Exogenous hydrogen sulfide (H2S) reduces blood pressure and prevents the progression of diabetic nephropathy in spontaneously hypertensive rats'. Renal Failure, 34 (2):203-210 [Details]
(2011)'The effect of losartan and carvedilol on vasopressor responses to adrenergic agonists and angiotensin II in the systemic circulation of Sprague Dawley rats'
Abdulla MH, Sattar MA, Abdullah NA, Khan MA, Anand Swarup KR, Johns EJ. (2011) 'The effect of losartan and carvedilol on vasopressor responses to adrenergic agonists and angiotensin II in the systemic circulation of Sprague Dawley rats'. Autonomic & Autacoid Pharmacology, 31 (1-2):13-20 [Details]
(2011)'The Relation between Fructose-Induced Metabolic Syndrome and Altered Renal Haemodynamic and Excretory Function in the Rat'
Abdulla MH, Sattar MA, Johns EJ. (2011) 'The Relation between Fructose-Induced Metabolic Syndrome and Altered Renal Haemodynamic and Excretory Function in the Rat'. International journal of nephrology, [DOI] [Details]
(2011)'Evidence for the role of α1A-adrenoceptor subtype in the control of renal haemodynamics in fructose-fed Sprague-Dawley rat'
Abdulla MH, Sattar MA, Johns EJ, Abdullah NA, Khan MA (2011) 'Evidence for the role of α1A-adrenoceptor subtype in the control of renal haemodynamics in fructose-fed Sprague-Dawley rat'. European Journal of Nutrition, 50 (8):689-697 [Details]
(2011)'The contribution of α1B-adrenoceptor subtype in the renal vasculature of fructose-fed Sprague-Dawley rats'
Abdulla MH, Sattar MA, Abdullah NA, Hye Khan MA, Anand Swarup KR, Johns EJ (2011) 'The contribution of α1B-adrenoceptor subtype in the renal vasculature of fructose-fed Sprague-Dawley rats'. European Journal of Nutrition, 50 (4):251-260 [Details]
(2009)'Chronic treatment with losartan and carvedilol differentially modulates renal vascular responses to sympathomimetics compared to treatment with individual agents in normal Wistar Kyoto and spontaneously hypertensive rats'
Abdulla MH, Sattar MA, Abdullah NA, Khan MA, Abdallah HH, Johns EJ. (2009) 'Chronic treatment with losartan and carvedilol differentially modulates renal vascular responses to sympathomimetics compared to treatment with individual agents in normal Wistar Kyoto and spontaneously hypertensive rats'. European Journal of Pharmacology, 612 (1-3):69-74 [Details]
(2009)'Influence of sympathetic and AT-receptor blockade on angiotensin II and adrenergic agonist-induced renal vasoconstrictions in spontaneously hypertensive rats'
Abdulla MH, Sattar MA, Khan MA, Abdullah NA, Johns EJ. (2009) 'Influence of sympathetic and AT-receptor blockade on angiotensin II and adrenergic agonist-induced renal vasoconstrictions in spontaneously hypertensive rats'. Acta Physiologica, 195 (3):397-404 [Details]
(2008)'Effect of acute unilateral renal denervation on renal hemodynamics in spontaneously hypertensive rats'
Abdulla MH, Sattar MA, Salman IM, Abdullah NA, Ameer OZ, Khan MA, Johns EJ. (2008) 'Effect of acute unilateral renal denervation on renal hemodynamics in spontaneously hypertensive rats'. Autonomic & Autacoid Pharmacology, 28 (2-3):87-94 [Details]
(2008)'Inhibition of Ang II and renal sympathetic nerve influence dopamine-and isoprenaline-induced renal haemodynamic changes in normal Wistar-Kyoto and spontaneously hypertensive rats'
Abdulla MH, Sattar MA, Abdullah NA, Hazim AI, Anand Swarup KR, Rathore HA, Khan MA, Johns EJ. (2008) 'Inhibition of Ang II and renal sympathetic nerve influence dopamine-and isoprenaline-induced renal haemodynamic changes in normal Wistar-Kyoto and spontaneously hypertensive rats'. Autonomic & Autacoid Pharmacology, 28 (4):95-101 [Details]

Other Journals

 YearPublication
(2021)'Teaching physiology to medical students in the COVID-19 era with synchronous formative assessments utilising simultaneous, combined Zoom and Socrative platforms'
Mohammed H. Abdulla, Elizabeth Brint and Mark G. Rae (2021) 'Teaching physiology to medical students in the COVID-19 era with synchronous formative assessments utilising simultaneous, combined Zoom and Socrative platforms' Journal of Education, 2 (1) :12-32. [Details]

Conference Publications

 YearPublication
(2022)Experimental Biology
Sara Almarabeh, Ken D O'Halloran, Mohammed H. Abdulla (2022) Renal Sympathetic Nerve Activity Responses to Hypoxia and Hypercapnia in Rats Exposed to Chronic Intermittent Hypoxia Experimental Biology [DOI] [Details]
(2021)Experimental Biology
Sara Almarabeh, Eric F. Lucking, Ken D O'Halloran, Mohammed H. Abdulla (2021) Renal Sympathetic Nerve Activity and Heart Rate Responses to Renal Pelvic Infusion of Bradykinin and Capsaicin in Rats Exposed to Intermittent Hypoxia Experimental Biology [Details]
(2019)The Physiological Society Meeting
Mohammed H. Abdulla and Mark G. Rae (2019) Do pre-clinical medical students prefer summative or formative evaluations in physiology? The Physiological Society Meeting Aberdeen, UK, [Details]
(2020)Experimental Biology
Sara Almarabeh, Julie O’Neill, Jeremy Cavers, Ken D. O'Halloran, Mohammed H. Abdulla (2020) Baroreflex Control of Renal Sympathetic Nerve Activity and Renal Responses to Volume Expansion Following Intermittent Hypoxia in Rats Experimental Biology [DOI] [Details]
(2014)Experimental Biology
Abdulla MH, Johns EJ (2014) The role of brain angiotensin AT2 receptors and NO in the renal sympatho-inhibitory response to acute volume expansion in conscious rats Experimental Biology [Details]
(2013)The Physiological Society Meeting
Abdulla MH, Johns EJ (2013) TRPV1 blockade restores the high-pressure baroreflex control of renal sympathetic nerve activity in cisplatin induced renal failure rats The Physiological Society Meeting [Details]
(2013)Experimental Biology
Abdulla MH, Johns EJ (2013) Nitric oxide impacts on angiotensin AT2 receptors modulation of high-pressure baroreflex control of renal sympathetic nerve activity in rats Experimental Biology [Details]
(2012)The Physiological Society Meeting
Abdulla MH, Johns EJ (2012) Role of NO and angiotensin AT2 receptors in the cardiopulmonary baroreflex control of renal sympathetic nerve activity in anaesthetised rats The Physiological Society Meeting [Details]
(2011)Experimental Biology
Abdulla MH, Johns EJ, Sattar MA, Abdullah NA, Khan MA, Rathore HA. (2011) Influence of high-fructose feeding on functional α1-adrenoceptor subtypes in the rat kidney Experimental Biology [Details]
(2010)Experimental Biology
Abdulla MH, Sattar MA, Abdullah NA, Khan MA, Kolla RLA, Rathore HA, Ibraheem ZO, Johns EJ. (2010) Effect of carvedilol and losartan on renal responses to Ang II and adrenergic agonists in fructose-fed rat Experimental Biology [Details]

Reviews

 YearPublication
(2022)Renal denervation for atrial fibrillation: a comprehensive updated systematic review and meta-analysis.
Nawar K.;Mohammad A.;Johns E.J.;Abdulla M.H. (2022) Renal denervation for atrial fibrillation: a comprehensive updated systematic review and meta-analysis. Reviews [DOI] [Details]

Professional Activities

Honours and Awards

 YearTitleAwarding Body
2021National Teaching Hero The National Forum for The Enhancement of Teaching and Learning in Higher Education
2014The American Physiological Society Early Career Physiologist Travel Award The American Physiological Society
2012Hall of Fame high impact publications Universiti Sains Malaysia
2009Conference Travel Award Universiti Sains Malaysia
2001Ministry of Higher Education Best Student Award University of Baghdad
2010The American Physiological Society Early Career Physiologist Travel Award The American Physiological Society
2013The Physiological Society travel award to IUPS Meeting in Birmingham The Physiological Society, UK
2012The Physiological Society travel award to Society Meeting in Edinburgh The Physiological Society, UK
2010Vice Chancellor’s Award Universiti Sains Malaysia
2012Best Research Thesis in Pharmacy Award Universiti Sains Malaysia
2010Hall of Fame high impact publications Universiti Sains Malaysia
2009Janseen Pharmaceuticals Award Universiti Sains Malaysia
2008M.Sc Fellowship Award Universiti Sains Malaysia

Professional Associations

 AssociationFunctionFrom / To
The American Physiological Society Member01-AUG-07 /
The Physiological Society, UK Affiliate member11-APR-12 /
The Scandinavian Physiological Society Life-long member17-JUN-14 /
Malaysian Society for Physiology and Pharmacology Member15-AUG-07 /
The association of Iraqi Pharmacist Associate member01-JUL-01 /

Committees

 CommitteeFunctionFrom / To
Athena Swan School of Medicine Committee Member2022 /
Department of Physiology Progress Review Panel (PRP) Chair and examiner2021 /
Centre for Integration of Research, Teaching and Learning (CIRTL) board Fellow2018 /
Graduate Entry to Medicine Teaching and Oversight Committee Member2014 /

Employment

 EmployerPositionFrom / To
University College Cork College Lecturer/above the bar01-NOV-14 /
College of Pharmacy, University of Baghdad, Iraq Demonstrator01-MAR-03 / 01-JAN-07
Private Sector, Baghdad, Iraq Community Pharmacist01-OCT-01 / 01-JAN-07
Ministry of Health, Baghdad, Iraq Hospital Pharmacist01-OCT-01 / 01-OCT-02
The State Company for Drug Industry, Iraq Industrial Pharmacist (trainee)02-JAN-02 / 01-JAN-03
University College Cork Postdoctoral research fellow01-NOV-11 / 31-OCT-14

Education

 YearInstitutionQualificationSubject
2019University College Cork Masters of Artin Teaching and Learning in Higher Education
2017University College Cork Postgraduate Diploma Teaching & Learning in Higher EducationTeaching & Learning
2016University College Cork Certificate in Teaching and Learning in Higher EduTeaching and Learning
2012Universiti Sains Malaysia Ph.D.Physiology
2009Universiti Sains Malaysia M.Sc.Pharmacology
2001University of Baghdad B.Sc. (Hons) PharmacyPharmacy

Languages

 LanguageReadingWritingSpeaking
English FunctionalFunctionalFunctional
Arabic FluentFluentFluent

Outreach Activities

 Description

I contributed to TeachDigi initiative and my interview is available on UCC website.

I contributed to inclusive UCC initiative and my interview is available on UCC website.

Representative for Department of Physiology (Open day)

Seminar: Innervation of the kidney in renal injury and inflammation: A cause of deranged cardiovascular control.

https://chrisheadleand.com/2020/09/09/pedagogy-and-pancakes-session-5/ My talk about teaching and learning in a medical program in UCC during COVID

Journal Activities

 JournalRoleTo / From
American Journal Of Hypertension Referee-
Frontiers In Pharmacology Referee01-MAY-20 -
Frontiers In Immunology Referee-
Frontiers In Physiology Referee01-MAY-20 -
Renal Failure Referee-
Journal Of Pharmacy And Pharmacology Referee-
Andrologia Referee-

Other Activities

 Description

Physicians' Services Incorporated Foundation in Canada

Teaching Activities

Teaching Interests


- Contribute to teaching and examination in the GEM, FM, PL and PF programmes.
- Preparation and delivery of lectures, labs and tutorials.
- Facilitation of small group learning for the GEM programme.
- Preparation of continuous assessment, summer/autumn/winter exam papers.
- Marking and assessing performance.
- Answering students’ esquires and providing feedback about the material.
- Oral examination of GEM and viva voce for Physiology science degree programme.
- GEM exams and timetable meetings.
- Physiology department undergraduate and postgraduate committees.
- GEM open day contributor.

  • Total number of scheduled contact teaching hours                                             = 124 hours
  • Total number of assessment and feedback hours                                                 = 62 hours
  • Total number of supervision hours of undergraduate laboratory project            = 25 hours
  • Total number of supervision hours of undergraduate literature review project  = 39 hours

Ø
Undergraduate Teaching: I teach on 12 undergraduate modules in 1st and 2nd year graduate entry medicine (GM), direct entry medicine (FM), medical science and health (MH), and 3rd & 4th year B.Sc. Physiology (PL) using a variety of teaching formats such as formal lectures, tutorials, small group learning (SGL), student projects and laboratory practical as listed below:


1.   
GM1001 (2014-present) Graduate Entry to Medicine (20 credits, 70-80 students):
○ Lectures 5 hours              Labs 2 hours      Tutorials 5 hours            SGL, 9 hours      = 21 hours
○ Assessment & feedback                3 hours                                                                      =  3 hours

2.   
GM1002 (2014-present) Graduate Entry to Medicine (20 credits, 70-80 students):
○ Lectures 14 hours             Labs 6 hours      Tutorials 8 hours            SGL, 4 hours      = 32 hours  
○ Assessment & feedback                3 hours                                                                       = 3 hours

3.   
GM1003 (2014-present) Graduate Entry to Medicine (15 credits, 70-80 students):

○ Lectures 5 hours              Labs 2 hours      Tutorials 6 hours            SGL, 3 hours      = 16 hours
○ Assessment & feedback                3 hours                                                                      = 3 hours

4.   
GM2001 (2014-present) Graduate Entry to Medicine (10 credits, 70-80 students):

○ Lectures 4 hours              Labs 2 hours      Tutorials 4 hours            SGL, 3 hours      = 13 hours
○ Assessment & feedback                3 hours                                                                      = 3 hours

5.   
FM2102 (2014-present) Direct Entry to Medicine (10 credits, ~120 students):

○ Lectures 9 hours              Labs 12 hours    Tutorials 4 hours                                       = 25 hours
○ Assessment & feedback                3 hours                                                                     = 3 hours

6.   
MH2102 (2019-present) Medical & Health Science (5 credits, ~30 students):

○ Lectures (with FM2102)   Labs 3 hours                                                                          = 3 hours
○ Assessment & feedback                3 hours                                                                     = 3 hours

7.   
PL3023 (2014-present) Module Coordinator BSc in Physiology (5 credits, ~18 students):

○ Lectures (with FM2102)   Labs 6 hours      Tutorials 4 hours                                        = 10 hours
○ Assessment & feedback                8 hours                                                                     =  8 hours

8.   
PL3025 (2014-present) Physiology, Experimental Design and Data Analysis (5 credits, 2-3 students):

○ Supervision of undergraduate literature review project                                                   = 14 hours

9.   
PL4020 (2014-present) BSc in Physiology, Final Year Project (20 credits, 1-3 students):

○ Supervision of undergraduate laboratory project                                                            = 25 hours

10.
PL3001 (2020-present) Medical & Health Science, Pathophysiology (5 credits, ~30 students):

○ Lectures  2 hours                                                                                                           = 2 hours
○ Assessment & feedback                 6 hours                                                                    = 6 hours

11.
GM2030 & MX4091 (2021-present) Research for Medicine and Health I (5 credits, 4 students):
○ Supervision of undergraduate literature review project                                                  = 25 hours

12.
PL4015 (2021-present) BSc in Physiology, Microbiome and Physiology (5 credit, ~18 students):

○ Lectures  2 hours                                                                                                           = 2 hours

Ø
Postgraduate Teaching
13.TL6003 & TL6004 (2019-present) CITRL, Certificate in Teaching & Learning in higher Ed.:
○ Assessment & feedback                 30 hours                                                                 = 30 hours

Recent Postgraduates

 Graduation YearStudent NameInstitutionDegree TypeThesis Title
2021Sara ALMarabeh University College CorkDoctor of PhilosophyBaroreflex control of blood pressure in chronic intermittent hypoxia-induced hypertension: Role of renal afferent nerve receptors

Research Information

Internal Collaborators

 NameInstituteCountry
Professor Edward J Johns Department of PhysiologyIRELAND
Dr Hazim Markos University College CorkIRELAND
Professor Ken O'Halloran University College CorkIRELAND

Contact details

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Physiology Department

Fiseolaíocht

Western Gateway Building Western Road University College Cork

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