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Physiology

Research Profiles

Dr Mark Rae PhD, BSc

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Dr Mark Rae PhD, BSc

     

Peer Reviewed Journals

Ruane-O'Hora, T,Rae, MG,Markos, F; (2011) 'Effect of clazosentan, a selective endothelin A receptor antagonist, and tezosentan, a dual endothelin A/B antagonist, on pulsatile shear stress induced constriction of the iliac in the anaesthetized pig'. Clinical and Experimental Pharmacology and Physiology, 38 :515-520. [DOI] [Details]
Munro, G,Erichsen, HK,Rae, MG,Mirza, NR; (2011) 'A question of balance - Positive versus negative allosteric modulation of GABA(A) receptor subtypes as a driver of analgesic efficacy in rat models of inflammatory and neuropathic pain'. Neuropharmacology, 61 :121-132. [DOI] [Details]
Rae MG, Irving AJ; (2004) 'Both mGluR1 and mGluR5 mediate Ca2+ release and inward currents in hippocampal CA1 pyramidal neurons'. Neuropharmacology, 46 (8):1057-1069. [DOI] [Details]
RAE, M.G. & IRVING, A.J.; (2004) 'Both mGluR1 and mGluR5 mediate Ca2+ release and inward currents in CA1 pyramidal neurons'. Neuropharmacology, 46 :1057-1069. [Details]
Rae Mg Fau - Irving, Andrew J.,Irving, A. J.; (2004) 'Both mGluR1 and mGluR5 mediate Ca2+ release and inward currents in hippocampal. Neuropharmacology'. Neuropharmacology, 46 (8):1057-69. [Details]
Shanley LJ, Irving AJ, Rae MG, Ashford ML, Harvey J; (2002) 'Leptin inhibits rat hippocampal neurons via activation of large conductance calcium-activated K+ channels'. Nature Neuroscience, 5 (4):299-300. [DOI] [Details]
Shanley Lj Fau - Irving, Andrew J.,Irving Aj Fau - Rae, Mark G.,Rae Mg Fau - Ashford, Mike L. J.,Ashford Ml Fau - Harvey, Jenni,Harvey, J.; (2002) 'Leptin inhibits rat hippocampal neurons via activation of large conductance. Nat Neurosci'. Nat Neurosci, 5 (4):299-300. [Details]
Irving Aj Fau - Rae, Mark G.,Rae Mg Fau - Coutts, Angela A.,Coutts, A. A.; (2002) 'Cannabinoids on the brain. ScientificWorldJournal'. ScientificWorldJournal, 2 :632-48. [Details]
Irving AJ, Coutts AA, Harvey J, Rae MG, Mackie K, Bewick GS, Pertwee RG; (2000) 'Functional expression of cell surface cannabinoid CB(1) receptors on presynaptic inhibitory terminals in cultured rat hippocampal neurons'. Neuroscience, 98 (2):253-262. [Details]
Irving Aj Fau - Coutts, A. A.,Coutts Aa Fau - Harvey, J.,Harvey J Fau - Rae, M. G.,Rae Mg Fau - Mackie, K.,Mackie K Fau - Bewick, G. S.,Bewick Gs Fau - Pertwee, R. G.,Pertwee, R. G.; (2000) 'Functional expression of cell surface cannabinoid CB(1) receptors on presynaptic. Neuroscience'. Neuroscience, 98 (2):253-62. [Details]
Rae Mg Fau - Martin, D. J.,Martin Dj Fau - Collingridge, G. L.,Collingridge Gl Fau - Irving, A. J.,Irving, A. J.; (2000) 'Role of Ca2+ stores in metabotropic L-glutamate receptor-mediated supralinear. J Neurosci'. J Neurosci, 20 (23):8628-36. [Details]
Koh Sd Fau - Bradley, K. K.,Bradley Kk Fau - Rae, M. G.,Rae Mg Fau - Keef, K. D.,Keef Kd Fau - Horowitz, B.,Horowitz B Fau - Sanders, K. M.,Sanders, K. M.; (1998) 'Basal activation of ATP-sensitive potassium channels in murine colonic smooth. Biophys J'. Biophys J, 75 (4):1793-800. [Details]
Rae Mg Fau - Fleming, N.,Fleming N Fau - McGregor, D. B.,McGregor Db Fau - Sanders, K. M.,Sanders Km Fau - Keef, K. D.,Keef, K. D.; (1998) 'Control of motility patterns in the human colonic circular muscle layer by. J Physiol'. J Physiol, 510 ( Pt 1) :309-20. [Details]
Rae Mg Fau - Khoyi, M. A.,Khoyi Ma Fau - Keef, K. D.,Keef, K. D.; (1998) 'Modulation of cholinergic neuromuscular transmission by nitric oxide in canine. Am J Physiol'. Am J Physiol, 275 (6 Pt 1). [Details]
Rae Mg Fau - Muir, T. C.,Muir, T. C.; (1996) 'Neuronal mediators of inhibitory junction potentials and relaxation in the. J Physiol'. J Physiol, 493 ( Pt 2) :517-27. [Details]
Robertson Sj Fau - Rae, M. G.,Rae Mg Fau - Rowan, E. G.,Rowan Eg Fau - Kennedy, C.,Kennedy, C.; (1996) 'Characterization of a P2X-purinoceptor in cultured neurones of the rat dorsal. Br J Pharmacol'. Br J Pharmacol, 118 (4):951-6. [Details]
Rae Mg Fau - Rotondo, D.,Rotondo D Fau - Dutta-Roy, A. K.,Dutta-Roy, A. K.; (1992) 'Regulation of prostaglandin E2 binding to a murine macrophage cell line, P388D1. Biochim Biophys Acta'. Biochim Biophys Acta, 1135 (3):343-8. [Details]
Rae Mg Fau - Rotondo, D.,Rotondo D Fau - Milton, A. S.,Milton As Fau - Dutta-Roy, A. K.,Dutta-Roy, A. K.; (1992) 'Interleukin-1 inhibits PGE2 binding to macrophage-like P388D1 cells by a cyclic. Biochim Biophys Acta'. Biochim Biophys Acta, 1138 (1):75-9. [Details]
Dutta-Roy AK, Rae MG, Milton AS, Rotondo D; (1991) 'Stimulation of prostaglandin E2 binding to a murine macrophage cell line (P388D1) by insulin'. Biochemical Society Transactions, 19 (4). [Details]
Dutta-Roy Ak Fau - Rae, M. G.,Rae Mg Fau - Milton, A. S.,Milton As Fau - Rotondo, D.,Rotondo, D.; (1991) 'Stimulation of prostaglandin E2 binding to a murine macrophage cell line (P388D1). Biochem Soc Trans'. Biochem Soc Trans, 19 (4). [Details]
 

Conference Publications

Rae, MG; Thompson, J; Sharkey, J; (2010) The putative TRP channel antagonists, SKF96365, flufenamic acid and 2-APB are non-competitive antagonists at recombinant alpha1, beta2, gamma2 GABAA receptors Neuroscience Ireland 2010 [Details]
MORLEY, S.J., KEOGH, M.K.& RAE, M.G (2011) Evidence of altered intracellular calcium handling in week old cultured hippocampal neurones of a murine model of Alzheimer’s disease (3xTg AD) RAMI [Details]
RAE, M.G. & IRVING, A.J.; (2003) Pharmacology of the group I metabotropic receptor-mediated responses in rat CA1 hippocampal neurones J. Physiol [Details]
WHITE, A.M., RAE, M.G., IRVING, A.J. & PLATT, B.; (2003) Group I mGluR-induced calcium signalling in the rat superficial superior colliculus J. Physiol [Details]
RAE, M.G & IRVING, A.J. ; (2003) Metabotropic glutamate receptors (mGluRs) and dynamic endoplasmic reticulum (ER) loading in CA1 pyramidal neurons Soc. Neuroscience Abs [Details]
RAE, M.G. & IRVING, A.J.; (2001) Relationship between group I metabotropic glutamate receptor-activated inward currents and supralinear calcium signalling in hippocampal neurons Soc. Neuroscience Abs [Details]
IRVING, A.J., CALDWELL, D., RAE, M.G., BEWICK, G & COUTTS A.A.; (2001) Functional expression of cell surface CB1 receptors at synaptic terminals in cultured rat cerebellar granule cells Int. Cannabinoid Res. Soc [Details]
RAE, M.G. & IRVING, A.J.; (2000) A novel coincidence detection mechanism involving mGlu receptors in the rat hippocampus J. Physiol [Details]
RAE, M.G. & IRVING, A.J.; (1999) Effects of cyclopiazonic acid on intracellular Ca2+ levels in cultured hippocampal neurones J. Physiol [Details]
RAE, M.G., KHOYI, M. & KEEF, K.D; (1997) Interaction between cholinergic and nitrergic transmission in the canine colonic circular muscle layer Gastroenterology [Details]
RAE, M.G., ROWAN, E.G. & KENNEDY, C.; (1996) Further characterisation of P2X-purinoceptors in cultured neurones of the rat dorsal root ganglia Drug Development Research [Details]
RAE, M.G., ROWAN, E.G. & KENNEDY, C. ; (1996) Characterisation of P2X-purinoceptors in neurones of the neonatal rat dorsal root ganglia Br. J. Pharmacol [Details]
RAE, M.G. & MUIR, T.C. ; (1995) Suramin reveals two distinct neuronally-mediated IJP components in the guinea-pig internal anal sphincter (gpIAS) Br. J. Pharmacol [Details]
RAE, M.G., QUINN, P. & MUIR, T.C. ; (1995) Alterations in both cAMP and cGMP levels of the guinea-pig internal anal sphincter (gpIAS) in response to neuronal stimulation and drugs Neurogastroenterology and Motility [Details]
RAE, M.G. & MUIR, T.C.; (1994) Both ATP and Nitric Oxide (NO) may be involved in the neuronally-mediated relaxation of the guinea-pig internal anal sphincter (gpIAS) Br. J. Pharmacol [Details]
RAE, M.G. & MUIR, T.C.; (1993) Neuronally-mediated inhibition in the guinea-pig internal anal sphincter (gpIAS) ¿ indirect nitric oxide involvement J. Gastrointestinal Motility [Details]
SMITH, A.D., RAE, M.G. & MUIR, T.C.; (1992) Excitation and inhibition by nitric oxide (NO) in smooth muscle Congress of the International Union of Physiological Sciences XXXII [Details]
RAE, M.G. & MUIR, T.C. ; (1992) Nitrovasodilators potentiate and inhibit spontaneous electrical and mechanical activity in the guinea-pig internal anal sphincter (gpIAS) Br. J. Pharmacol [Details]
 

Abstract

Rae, MG,Thompson, J,Sharkey, J (2011) THE PUTATIVE TRP CHANNEL ANTAGONISTS, SKF96365, FLUFENAMIC ACID AND 2-APB ARE NON-COMPETITIVE ANTAGONISTS AT RECOMBINANT alpha(1)beta(1)gamma(2) GABA(A) RECEPTORS. Abstract [Details]
RAE, M.G & IRVING, A.J. ; (2003) Metabotropic glutamate receptors (mGluRs) and dynamic endoplasmic reticulum (ER) loading in CA1 pyramidal neurons. Abstract [Details]
RAE, M.G. & IRVING, A.J. ; (2003) Pharmacology of the group I metabotropic receptor-mediated responses in rat CA1 hippocampal neurones. Abstract [Details]
WHITE, A.M., RAE, M.G., IRVING, A.J. & PLATT, B.; (2003) Group I mGluR-induced calcium signalling in the rat superficial superior colliculus. Abstract [Details]
                                                                                                                                                             
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