Biography
Ted Dinan is Professor of Psychiatry and a Principal Investigator in the Alimentary Pharmabiotic Centre at University College Cork. He was previously Chair of Clinical Neurosciences and Professor of Psychological Medicine at St. Bartholomew's Hospital, London. Prior to that he was a Senior Lecturer in Psychiatry at Trinity College Dublin. He has worked in research laboratories on both sides of the Atlantic and has a PhD in Pharmacology from the University of London. He is a Fellow of the Royal Colleges of Physicians and Psychiatrists and a Fellow of the American College of Physicians. He has published over 450 papers and numerous books on the pharmacology and neurobiology of affective disorders. His primary research focus is on immune and endocrine aspects of depression and irritable bowel syndrome.
Research Interests
Publications
Books
| Year | Publication | |
|---|---|---|
| (2001) | Concise Textbook of Adult Psychiatry. Mirza KAH, Mirza S, Dinan TG . ; (2001) Concise Textbook of Adult Psychiatry. London: Medic Press. [Details] | |
| (1997) | Medical Management of Depression. Dinan TG ; (1997) Medical Management of Depression. London: Phase IV Communications. [Details] | |
| (1992) | Anxiety Disorders: From Pathophysiology to Pharmacology. London: . Emilieu G, Mistelli C, Dinan TG; (1992) Anxiety Disorders: From Pathophysiology to Pharmacology. London: . London: Martin Dunitz. [Details] | |
| (1992) | Multiple Choice Questions for the Membership in Psychiatry London. Yatham L and Dinan TG ; (1992) Multiple Choice Questions for the Membership in Psychiatry London. London: CNS. [Details] | |
| (1992) | The Scientific Basis of Psychiatry: A Concise Text. London: Medic Press. Dinan TG; (1992) The Scientific Basis of Psychiatry: A Concise Text. London: Medic Press. London: Medic Press. [Details] | |
| (1985) | The Scientific Basis of Psychiatry: Examination Notes. Dinan TG; (1985) The Scientific Basis of Psychiatry: Examination Notes. Bristol: John Wright. [Details] |
Book Chapters
| Year | Publication | |
|---|---|---|
| (2010) | 'The Hypothalamic-pituitary-adrenal axis in depression' Julio-Piper, M; Dinan, TG; (2010) 'The Hypothalamic-pituitary-adrenal axis in depression' In: Depression: From Psychopathology to Pharmacotherapy. Basel: Karger. [Details] | |
| (2008) | 'Food and Mood' Dinan TG; (2008) 'Food and Mood' In: Food and Health in the New Millennium. New York: Nova Science. [Details] | |
| (2005) | 'Biological factors sustaining hypothalamic-pituitary-adrenal axis overactivation in affective disorders: focus on vasopressin' Dinan TG, O'Brien S, Scott LV; (2005) 'Biological factors sustaining hypothalamic-pituitary-adrenal axis overactivation in affective disorders: focus on vasopressin' In: Bipolar Disorder: The Upswing in Research and Treatment. London: Taylor & Francis. [Details] | |
| (2008) | 'Developing more efficacious antidepressant medications: Improving and aligning preclinical and clinical assessment tools' Cryan JF, Sanchez C, Dinan TG, Borsini F; (2008) 'Developing more efficacious antidepressant medications: Improving and aligning preclinical and clinical assessment tools' In: Animal and Translational Models for Drug Discovery: Psychiatric Disorders. NY: Elsevier. [Details] |
Edited Books
| Year | Publication | |
|---|---|---|
| (1997) | Understanding the Biology of Mental Disorders Dinan TG (Ed.). (1997) Understanding the Biology of Mental Disorders Understanding the Biology of Mental Disorders. London: SP Science. [Details] | |
| (1990) | Principles and Practice of Biological Psychiatry Vol. 2 Dinan TG (Ed.). (1990) Principles and Practice of Biological Psychiatry Vol. 2 Principles and Practice of Biological Psychiatry Vol. 2. London: CNS. [Details] | |
| (1990) | Principles and Practice of Biological Psychiatry Vol.1 Dinan TG (Ed.). (1990) Principles and Practice of Biological Psychiatry Vol.1 Principles and Practice of Biological Psychiatry Vol.1. London: CNS. [Details] |
Peer Reviewed Journals
| Year | Publication | |
|---|---|---|
| (2010) | 'A Sensitive Period of Mice Inhibitory System to Neonatal GABA Enhancement by Vigabatrin is Brain Region Dependent' Levav-Rabkin, T; Melamed, O; Clarke, G; Farber, M; Cryan, JF; Dinan, TG; Grossman, Y; Golan, HM; (2010) 'A Sensitive Period of Mice Inhibitory System to Neonatal GABA Enhancement by Vigabatrin is Brain Region Dependent'. Neuropsychopharmacology, 35 :1138-1154 [DOI] [Details] | |
| (2010) | 'Riluzole Normalizes Early-Life Stress-Induced Visceral Hypersensitivity in Rats: Role of Spinal Glutamate Reuptake Mechanisms' Gosselin, RD; O'Connor, RM; Tramullas, M; Julio-Pieper, M; Dinan, TG; Cryan, JF; (2010) 'Riluzole Normalizes Early-Life Stress-Induced Visceral Hypersensitivity in Rats: Role of Spinal Glutamate Reuptake Mechanisms'. Gastroenterology, 138 :2418-2425 [DOI] [Details] | |
| (2010) | 'Differential stress-induced alterations of colonic corticotropin-releasing factor receptors in the Wistar Kyoto rat' O'Malley, D; Julio-Pieper, M; Gibney, SM; Gosselin, RD; Dinan, TG; Cryan, JF; (2010) 'Differential stress-induced alterations of colonic corticotropin-releasing factor receptors in the Wistar Kyoto rat'. Neurogastroenterology and Motility, 22 :301-311 [DOI] [Details] | |
| (2010) | 'Strain differences in the neurochemical response to chronic restraint stress in the rat: Relevance to depression' O'Mahony CM, Clarke G, Gibney S, Dinan TG, Cryan JF; (2010) 'Strain differences in the neurochemical response to chronic restraint stress in the rat: Relevance to depression'. Pharmacology Biochemistry and Behavior, [DOI] [Details] | |
| (2010) | 'Plasma Cytokine Profiles in Females With Irritable Bowel Syndrome and Extra-Intestinal Co-Morbidity' Scully, Paul; McKernan, Declan P; Keohane, John; Groeger, David; Shanahan, Fergus; Dinan, Timothy G; Quigley, Eamonn M. M.; (2010) 'Plasma Cytokine Profiles in Females With Irritable Bowel Syndrome and Extra-Intestinal Co-Morbidity'. American Journal of Gastroenterology, 105 (10):2235-2243 [DOI] [Details] | |
| (2010) | 'Restraint stress-induced brain activation patterns in two strains of mice differing in their anxiety behaviour' O'Mahony, CM; Sweeney, FF; Daly, E; Dinan, TG; Cryan, JF; (2010) 'Restraint stress-induced brain activation patterns in two strains of mice differing in their anxiety behaviour'. Behavioural Brain Research, 213 :148-154 [DOI] [Details] | |
| (2010) | 'Alterations in colonic corticotropin-releasing factor receptors in the maternally separated rat model of irritable bowel syndrome: Differential effects of acute psychological and physical stressors' O'Malley, D; Dinan, TG; Cryan, JF; (2010) 'Alterations in colonic corticotropin-releasing factor receptors in the maternally separated rat model of irritable bowel syndrome: Differential effects of acute psychological and physical stressors'. Peptides, 31 :662-670 [DOI] [Details] | |
| (2010) | 'A novel role for the metabotropic glutamate receptor-7: modulation of faecal water content and colonic electrolyte transport in the mouse' Pieper-Julio, M; Hyland, NP; Bravo, JA; Dinan, TG; Cryan, JF; (2010) 'A novel role for the metabotropic glutamate receptor-7: modulation of faecal water content and colonic electrolyte transport in the mouse'. British Journal of Pharmacology, 160 :367-375 [DOI] [Details] | |
| (2010) | 'Distinct alterations in colonic morphology and physiology in two rat models of enhanced stress-induced anxiety and depression-like behaviour' O'Malley, D; Julio-Pieper, M; Gibney, SM; Dinan, TG; Cryan, JF; (2010) 'Distinct alterations in colonic morphology and physiology in two rat models of enhanced stress-induced anxiety and depression-like behaviour'. Stress (Amsterdam, Netherlands), 13 :114-122 [DOI] [Details] | |
| (2010) | 'Marked elevations in pro-inflammatory polyunsaturated fatty acid metabolites in females with irritable bowel syndrome' Clarke, G; Fitzgerald, P; Hennessy, AA; Cassidy, EM; Quigley, EMM; Ross, P; Stanton, C; Cryan, JF; Dinan, TG; (2010) 'Marked elevations in pro-inflammatory polyunsaturated fatty acid metabolites in females with irritable bowel syndrome'. Journal of Lipid Research, 51 :1186-1192 [DOI] [Details] | |
| (2010) | 'The effects of repeated social interaction stress on behavioural and physiological parameters in a stress-sensitive mouse strain' Savignac, HM; Hyland, NP; Dinan, TG; Cryan, JF; (2010) 'The effects of repeated social interaction stress on behavioural and physiological parameters in a stress-sensitive mouse strain'. Behavioural Brain Research, [DOI] [Details] | |
| (2009) | 'Kynurenine Pathway In Psychosis: Evidence of Increased Tryptophan Degradation' Barry, S, Clarke, G, Scully, P, Dinan, TG; (2009) 'Kynurenine Pathway In Psychosis: Evidence of Increased Tryptophan Degradation'. Journal of Psychopharmacology, 23 (3):287-294 [DOI] [Details] | |
| (2009) | 'Region Specific Decrease In Glial Fibrillary Acidic Protein Immunoreactivity In The Brain of A Rat Model of Depression' Gosselin, RD, Gibney, S, O'Malley, D, Dinan, TG, Cryan, JF; (2009) 'Region Specific Decrease In Glial Fibrillary Acidic Protein Immunoreactivity In The Brain of A Rat Model of Depression'. Neuroscience, 159 (2):915-925 [DOI] [Details] | |
| (2009) | 'Does The Ability to Sustain Attention Underlie Symptom Severity In Schizophrenia?' O'Grada, C, Barry, S, McGlade, N, Behan, C, Haq, F, Hayden, J, O'Donoghue, T, Peel, R, Morris, DW, O'Callaghan, E, Gill, M, Corvin, AP, Dinan, TG, Donohoe, G; (2009) 'Does The Ability to Sustain Attention Underlie Symptom Severity In Schizophrenia?'. Schizophrenia Research, 107 (2-3):319-323 [DOI] [Details] | |
| (2009) | 'Is Clinical Insight The Same As Cognitive Insight In Schizophrenia?' Donohoe, G, Hayden, J, McGlade, N, O'Grada, C, Burke, T, Barry, S, Behan, C, Dinan, TG, O'Callaghan, E, Gill, M, Corvin, AP; (2009) 'Is Clinical Insight The Same As Cognitive Insight In Schizophrenia?'. Journal of The International Neuropsychological Society, 15 (3):471-475 [DOI] [Details] | |
| (2009) | 'Tryptophan Degradation In Irritable Bowel Syndrome: Evidence of Indoleamine 2,3-Dioxygenase Activation In A Male Cohort' Clarke, G, Fitzgerald, P, Cryan, JF, Cassidy, EM, Quigley, EM, Dinan, TG; (2009) 'Tryptophan Degradation In Irritable Bowel Syndrome: Evidence of Indoleamine 2,3-Dioxygenase Activation In A Male Cohort'. BMC Gastroenterology, 9 (NA) [DOI] [Details] | |
| (2009) | 'Killing The Blues: A Role For Cellular Suicide (Apoptosis) In Depression and The Antidepressant Response?' McKernan, DP, Dinan, TG, Cryan, JF; (2009) 'Killing The Blues: A Role For Cellular Suicide (Apoptosis) In Depression and The Antidepressant Response?'. (4):246-263 [DOI] [Details] | |
| (2009) | 'Early Life Stress Alters Behavior, Immunity, and Microbiota in Rats: Implications for Irritable Bowel Syndrome and Psychiatric Illnesses' O'Mahony, SM,Marchesi, JR,Scully, P,Codling, C,Ceolho, AM,Quigley, EMM,Cryan, JF,Dinan, TG; (2009) 'Early Life Stress Alters Behavior, Immunity, and Microbiota in Rats: Implications for Irritable Bowel Syndrome and Psychiatric Illnesses'. Biological Psychiatry, 65 :263-267 [DOI] [Details] | |
| (2009) | 'Toll-Like Receptor mRNA Expression Is Selectively Increased in the Colonic Mucosa of Two Animal Models Relevant to Irritable Bowel Syndrome' McKernan, DP,Nolan, A,Brint, EK,O'Mahony, SM,Hyland, NP,Cryan, JF,Dinan, TG; (2009) 'Toll-Like Receptor mRNA Expression Is Selectively Increased in the Colonic Mucosa of Two Animal Models Relevant to Irritable Bowel Syndrome'. Plos One, 4 [DOI] [Details] | |
| (2009) | 'Investigating the inflammatory phenotype of major depression: Focus on cytokines and polyunsaturated fatty acids' Dinan, T,Siggins, L,Scully, P,O'Brien, S,Ross, P,Stanton, C; (2009) 'Investigating the inflammatory phenotype of major depression: Focus on cytokines and polyunsaturated fatty acids'. Journal of Psychiatric Research, 43 :471-476 [DOI] [Details] | |
| (2008) | 'The probiotic Bifidobacteria infantis: An assessment of potential antidepressant properties in the rat' Desbonnet, L,Garrett, L,Clarke, G,Bienenstock, J,Dinan, TG; (2008) 'The probiotic Bifidobacteria infantis: An assessment of potential antidepressant properties in the rat'. Journal of Psychiatric Research, 43 :164-174 [DOI] [Details] | |
| (2008) | 'Increased Tumor Necrosis Factor-Alpha Concentrations With Interleukin-4 Concentrations In Exacerbations of Schizophrenia' O'Brien, SM, Scully, P, Dinan, TG; (2008) 'Increased Tumor Necrosis Factor-Alpha Concentrations With Interleukin-4 Concentrations In Exacerbations of Schizophrenia'. Psychiatry Research, 160 (3):256-262 [DOI] [Details] | |
| (2007) | 'An isocratic high performance liquid chromatography method for the determination of GABA and glutamate in discrete regions of the rodent brain' Clarke, G,Mahony, S,Malone, G,Dinan, TG; (2007) 'An isocratic high performance liquid chromatography method for the determination of GABA and glutamate in discrete regions of the rodent brain'. Journal of Neuroscience Methods, 160 :223-230 [DOI] [Details] | |
| (2007) | 'Mucosal cytokine imbalance in irritable bowel syndrome (IBS)' Quigley, Eamonn M. and McSharry, John and O'Mahony, Liam and Fanning, Aine and Bairead, Emer and Scully, Paul and Tiesman, Jav and Fulmer, Andy and Dinan, Timothi and Sherlock, Graham and Shanahan, Fergus; (2007) 'Mucosal cytokine imbalance in irritable bowel syndrome (IBS)'. AMERICAN JOURNAL OF GASTROENTEROLOGY, 102 (Suppl. 2) [Details] | |
| (2006) | 'Cytokine profiles in bipolar affective disorder: Focus on acutely ill patients' O'Brien, SM,Scully, P,Scott, LV,Dinan, TG; (2006) 'Cytokine profiles in bipolar affective disorder: Focus on acutely ill patients'. Journal of Affective Disorders, 90 :263-267 [DOI] [Details] | |
| (2006) | 'Cutaneous glucocorticoid receptor sensitivity and pro-inflammatory cytokine levels in antidepressant-resistant depression' Fitzgerald, P,O'Brien, SM,Scully, P,Rijkers, K,Scott, LV,Dinan, TG; (2006) 'Cutaneous glucocorticoid receptor sensitivity and pro-inflammatory cytokine levels in antidepressant-resistant depression'. International Journal of Psychological Medicine, 36 :37-43 [DOI] [CORA Link] [Details] | |
| (2006) | 'Antidepressant therapy and C-reactive protein levels' O'Brien, SM,Scott, LV,Dinan, TG; (2006) 'Antidepressant therapy and C-reactive protein levels'. Rna-A Publication of The Rna Society, 188 :449-452 [Details] | |
| (2006) | 'Functional dyspepsia: Are psychosocial factors of relevance?' Barry, S,Dinan, TG; (2006) 'Functional dyspepsia: Are psychosocial factors of relevance?'. World Journal of Gastroenterology, 12 :2701-2707 [Details] | |
| (2006) | 'Central serotonergic and noradrenergic receptors in functional dyspepsia' O'Mahony, S,Dinan, TG,Keeling, PW,Chua, ASB; (2006) 'Central serotonergic and noradrenergic receptors in functional dyspepsia'. World Journal of Gastroenterology, 12 :2681-2687 [Details] | |
| (2005) | 'Stress: the shared common component in major mental illnesses' Dinan, TG; (2005) 'Stress: the shared common component in major mental illnesses'. European Psychiatry, 20 :326-328 [Details] | |
| (2005) | 'Changes in hypothalamic-pituitary-adrenal axis measures after vagus nerve stimulation therapy in chronic depression' O'Keane, V,Dinan, TG,Scott, L,Corcoran, C; (2005) 'Changes in hypothalamic-pituitary-adrenal axis measures after vagus nerve stimulation therapy in chronic depression'. Biological Psychiatry, 58 :963-968 [DOI] [Details] | |
| (2004) | 'Further neuroendocrine evidence of enhanced vasopressin V-3 receptor responses in melancholic depression' Dinan, TG,O'Brien, S,Lavelle, E,Scott, LV; (2004) 'Further neuroendocrine evidence of enhanced vasopressin V-3 receptor responses in melancholic depression'. International Journal of Psychological Medicine, 34 :169-172 [DOI] [Details] | |
| (2002) | 'Altered hypothalamic cholinergic responses in patients with nonulcer dyspepsia: A study of pyridostigmine-stimulated growth hormone release' Dinan, TG,Scott, LV,Brady, D,McNamara, D,Keeling, PWN; (2002) 'Altered hypothalamic cholinergic responses in patients with nonulcer dyspepsia: A study of pyridostigmine-stimulated growth hormone release'. American Journal of Gastroenterology, 97 :1937-1940 [DOI] [Details] | |
| (2002) | 'Pituitary-adrenal response to naloxone in non-ulcer dyspepsia: Preliminary evidence for a reduction in central opioid tone' Scott, LV,Rathore, O,Dinan, TG,Keeling, PWN; (2002) 'Pituitary-adrenal response to naloxone in non-ulcer dyspepsia: Preliminary evidence for a reduction in central opioid tone'. Digestion, 65 :67-72 [Details] | |
| (2001) | 'Psychoneuroendocrinology of mood disorders' Dinan, TG; (2001) 'Psychoneuroendocrinology of mood disorders'. Current Opinion In Psychiatry, 14 :51-55 [Details] | |
| (2010) | 'Comparison of Hippocampal Metabotropic Glutamate Receptor 7 (mGlu(7)) mRNA Levels in Two Animal Models of Depression' O'Mahony, CM; Bravo, J; Dinan, TG; Cryan, JF; (2010) 'Comparison of Hippocampal Metabotropic Glutamate Receptor 7 (mGlu(7)) mRNA Levels in Two Animal Models of Depression'. Neuroscience Letters, [DOI] [Details] | |
| (2010) | 'Neonatal maternal separation in the rat impacts on the stress responsivity of central corticotropin-releasing factor receptors in adulthood' O'Malley, D; Dinan, TG; Cryan, JF; (2010) 'Neonatal maternal separation in the rat impacts on the stress responsivity of central corticotropin-releasing factor receptors in adulthood'. Psychopharmacology, [DOI] [Details] | |
| (2010) | 'Lean mean fat reducing ghrelin machine: hypothalamic ghrelin and ghrelin receptors as therapeutic targets in obesity' Schellekens, H; Dinan, TG; Cryan, JF; (2010) 'Lean mean fat reducing ghrelin machine: hypothalamic ghrelin and ghrelin receptors as therapeutic targets in obesity'. Neuropharmacology, 58 (1):2-16 [DOI] [Details] | |
| (2010) | 'Enhanced cholinergic-mediated increase in the pro-inflammatory cytokine IL-6 in irritable bowel syndrome: Role of muscarinic receptors' Dinan, TG; Clarke, G; Quigley, EMM; Scott, LV; Shanahan, F; Cryan, J; Cooney, J; Keeling, PWN; (2010) 'Enhanced cholinergic-mediated increase in the pro-inflammatory cytokine IL-6 in irritable bowel syndrome: Role of muscarinic receptors'. American Journal of Gastroenterology, [Details] | |
| (2010) | 'Colorectal distension-induced prefrontal cortex activation in the Wistar-Kyoto rat: implications for irritable bowel syndrome' Gibney, SM; Gosselin, RD; Dinan, TG; Cryan, JF; (2010) 'Colorectal distension-induced prefrontal cortex activation in the Wistar-Kyoto rat: implications for irritable bowel syndrome'. Neuroscience, 165 (3):675-683 [DOI] [Details] | |
| (2009) | 'A distinct subset of submucosal mast cells undergoes hyperplasia following neonatal maternal separation: a role in visceral hypersensitivity?' Hyland NP, Julio-Pieper M, O'Mahony SM, Bulmer DC, Lee K, Quigley EM, Dinan TG, Cryan JF; (2009) 'A distinct subset of submucosal mast cells undergoes hyperplasia following neonatal maternal separation: a role in visceral hypersensitivity?'. Gut, 58 (7):1029-101 [DOI] [Details] | |
| (2009) | 'Chain reactions: early-life stress alters the metabolic profile of plasma polyunsaturated fatty acids in adulthood' Clarke, G; O'Mahony, SM; Hennessy, AA; Ross, P; Stanton, C; Cryan, JF; Dinan, TG; (2009) 'Chain reactions: early-life stress alters the metabolic profile of plasma polyunsaturated fatty acids in adulthood'. Behavioural Brain Research, 205 (1):319-321 [DOI] [Details] | |
| (2009) | 'Killing the Blues: a role for cellular suicide (apoptosis) in depression and the antidepressant response?' McKernan DP, Dinan TG, Cryan JF; (2009) 'Killing the Blues: a role for cellular suicide (apoptosis) in depression and the antidepressant response?'. Progress In Neurobiology, 88 (4):246-263 [DOI] [Details] | |
| (2009) | 'Irritable bowel syndrome: role of food in pathogenesis and management' Morcos, A; Dinan, T; Quigley, EM; (2009) 'Irritable bowel syndrome: role of food in pathogenesis and management'. Journal of Digestive Diseases, 10 (4):237-46 [Details] | |
| (2009) | 'Irritable bowel syndrome: towards biomarker identification' Clarke, G; Quigley, EM; Cryan, JF; Dinan, TG; (2009) 'Irritable bowel syndrome: towards biomarker identification'. Trends In Molecular Medicine, 15 (10):478-489 [DOI] [Details] | |
| (2009) | 'Verapamil in treatment resistant depression: a role for the P-glycoprotein transporter?' Clarke G, O'Mahony SM, Cryan JF, Dinan TG; (2009) 'Verapamil in treatment resistant depression: a role for the P-glycoprotein transporter?'. Human Psychopharmacology, 24 (3):217-223 [DOI] [Details] | |
| (2009) | '5-HT(2B) receptors modulate visceral hypersensitivity in a stress-sensitive animal model of brain-gut axis dysfunction' O'Mahony, SM; Bulmer, DC; Coelho, AM; Fitzgerald, P; Bongiovanni, C; Lee, K; Winchester, W; Dinan, TG; Cryan, JF; (2009) '5-HT(2B) receptors modulate visceral hypersensitivity in a stress-sensitive animal model of brain-gut axis dysfunction'. Neurogastroenterology and Motility, [DOI] [Details] | |
| (2008) | 'Sexually dimorphic effects of maternal separation stress on corticotrophin-releasing factor and vasopressin systems in the adult rat brain' Desbonnet, L., Garrett, G., Daly, E., McDermott, K.W., and Dinan, T.G. ; (2008) 'Sexually dimorphic effects of maternal separation stress on corticotrophin-releasing factor and vasopressin systems in the adult rat brain'. International Journal of Developmental Neuroscience, 26 (3-4):259-268 [Details] | |
| (2006) | 'Depression and anxiety in rheumatoid arthritis: the role of perceived social support' Dinan, T, Zyrianova Y, Kelly BD, Gallagher, G, MCarthy, C, Molloy, MG; (2006) 'Depression and anxiety in rheumatoid arthritis: the role of perceived social support'. Irish Journal of Medical Science, 175 (2):32-36 [Details] | |
| (2006) | 'Plasma cytokine profiles in depressed patients who fail to respond to selective serotonin reuptake inhibitor therapy' Dinan, T, O'Brien, SM, Scully, Fitzgerald, P. Scott, LV; (2006) 'Plasma cytokine profiles in depressed patients who fail to respond to selective serotonin reuptake inhibitor therapy'. 24 (*):*-* [Details] | |
| (2006) | 'Therapeutic options: Addressing the current dilemma' Dinan, T; (2006) 'Therapeutic options: Addressing the current dilemma'. European Neuropsychopharmacology, 16 (Supplement 2):119-127 [Details] | |
| (2006) | 'The metabolic syndrome: time for a critical appraisal: joint statement from the American Diabetes Association and the European Association for the Study of Diabetes: response to Kahn et al' Dinan, TG, Citrome, L, Holt, RI; (2006) 'The metabolic syndrome: time for a critical appraisal: joint statement from the American Diabetes Association and the European Association for the Study of Diabetes: response to Kahn et al'. Diabetes Care, 1 (176):177-178 [Details] | |
| (2006) | 'Antidepressant therapy and C-reactive protein levels' Dinan, TG, O'Brien, SM, Scott, LV; (2006) 'Antidepressant therapy and C-reactive protein levels'. British Journal of Psychiatry, 188 (5):449-452 [Details] | |
| (2006) | 'Role of cholecystokinin and central serotonergic receptors in functional dyspepsia' Dinan, TG, Chua, AS, Keeling, PW; (2006) 'Role of cholecystokinin and central serotonergic receptors in functional dyspepsia'. 12 (9):1329-1335 [Details] | |
| (2005) | 'An overview of the central control of weight regulation and the effect of antipsychotic medication' Dinan, TG, Tighe, S; (2005) 'An overview of the central control of weight regulation and the effect of antipsychotic medication'. Journal of Psychopharmacology, 19 (Supplement 6):36-46 [Details] | |
| (2005) | 'Anatomy of melancholia: focus on hypothalamic-pituitary-adrenal axis overactivity and the role of vasopressin' Dinan, TG, Scott, LV; (2005) 'Anatomy of melancholia: focus on hypothalamic-pituitary-adrenal axis overactivity and the role of vasopressin'. Journal of Anatomy, 207 (3):259-264 [Details] | |
| (2005) | 'Vasopressin: the neglected target for stress modulation?' Dinan, TG; (2005) 'Vasopressin: the neglected target for stress modulation?'. Stress and Health, 21 (3):145-146 [Details] | |
| (2005) | 'Challenges in advancing mental and physical health of patients with serious mental illness' Dinan, TG, Dursun, S, Bushe, C, Thakore, J; (2005) 'Challenges in advancing mental and physical health of patients with serious mental illness'. Journal of Psychopharmacology, 16 (Supplement 6):3-5 [Details] | |
| (2004) | 'Understanding schizophrenia and diabetes' Dinan, TG, Peveler, R, Holt, R; (2004) 'Understanding schizophrenia and diabetes'. 65 (8):485-488 [Details] | |
| (2004) | 'Introduction to supplement' Dinan TG; (2004) 'Introduction to supplement'. British Journal of Psychiatry, 47 (*):S72-75 [Details] | |
| (2003) | 'Platelet surface glycoprotein expression in post-stroke depression: a preliminary study' Dinan, TG, Cassidy, EM, Walsh, MT, O'Connor, R, Condren RM, Ryan, M, O'Keane, V, Kenny D; (2003) 'Platelet surface glycoprotein expression in post-stroke depression: a preliminary study'. 118 (2):175-181 [Details] | |
| (2003) | 'Central 5-HT receptor hypersenstivity in migraine without aura' Dinan, TG, Cassidy, EM, Tomkins, E, Hardiman, O, O'Keane, V; (2003) 'Central 5-HT receptor hypersenstivity in migraine without aura'. 23 (1):29-34 [Details] | |
| (2003) | 'Differing central amine receptor sensitiviy in different migraine subtypes? A neuroendocrine study using buspirone' Dinan, TG, CAssidy, EM, Tomkins, E, Sharifi, N, Hardiman, O, O'Keane, V; (2003) 'Differing central amine receptor sensitiviy in different migraine subtypes? A neuroendocrine study using buspirone'. Journal of Pain, 101 (3):283-290 [Details] | |
| (2003) | 'Atypical antipsychotics and diabetic propensity: more questions than answers' Dinan, T, Kohen, D; (2003) 'Atypical antipsychotics and diabetic propensity: more questions than answers'. Human Psychopharmacology, 18 (8):1-3 [Details] | |
| (2002) | 'The pharmacology of mania: focus on olanzapine as a mood stabiliser' Dinan, TG; (2002) 'The pharmacology of mania: focus on olanzapine as a mood stabiliser'. 1 (3):215-221 [Details] | |
| (2002) | 'A preliminary study of buspirone stimulated prolactin release in generalised social phobia: evidence for enhanced serotonergic responsivity?' Dinan, TG, Condren, RM, Thakore, J; (2002) 'A preliminary study of buspirone stimulated prolactin release in generalised social phobia: evidence for enhanced serotonergic responsivity?'. European Neuropsychopharmacology, 12 (4):349-354 [Details] | |
| (2002) | 'Elevanted expression of integrin alpha(IIb) beta (IIIa) in drug-naive, first-episode schizophrenic patients' Dinan, TG, Ryan, M, Hillman, A, Condren, R, Kenny, D, Thakore, JH; (2002) 'Elevanted expression of integrin alpha(IIb) beta (IIIa) in drug-naive, first-episode schizophrenic patients'. Biological Psychiatry, 52 (9):874-879 [Details] | |
| (2002) | 'Treatment recommendations versus treatment reality: Their effect on compliance and persistence in patients with depression' Dinan, TG, Jupfer, DJ, Dunner, DL, Fava M; (2002) 'Treatment recommendations versus treatment reality: Their effect on compliance and persistence in patients with depression'. Online (*):*-* [Details] | |
| (2002) | 'Depression is associated with an increase in the expression of the platelet adhesion receptor glycoprotein Ib' Dinan, TG, Walsh, MT, Condren, RM, Ryan, M, Kenny, D; (2002) 'Depression is associated with an increase in the expression of the platelet adhesion receptor glycoprotein Ib'. Life Sciences, 70 (26):3155-3165 [Details] | |
| (2002) | 'Relapse prevention in major depression: A role for weekly fluoxetine' Dinan, TG; (2002) 'Relapse prevention in major depression: A role for weekly fluoxetine'. 1 (*):83-89 [Details] | |
| (2002) | 'Vasopressin as a target for antidepressant development: an assessment of the available evidence' Dinan, TG, Scott, LV; (2002) 'Vasopressin as a target for antidepressant development: an assessment of the available evidence'. Journal of Affective Disorders, 72 (2):113-124 [Details] | |
| (2002) | 'Lithium in bipolar mood disorder: Is it time for an obituary?' Dinan, TG; (2002) 'Lithium in bipolar mood disorder: Is it time for an obituary?'. British Medical Journal, 324 (7344):989-990 [Details] | |
| (2001) | 'Orlistat in the treatment of antipsychotic induced weight gain: Two case reports' Dinan TG, Tobin A; (2001) 'Orlistat in the treatment of antipsychotic induced weight gain: Two case reports'. 7 (*):14-15 [Details] | |
| (2001) | 'Novel approaches to the treatment of depression by modulating the hypothalamic-pituitary-adrenal axis' Dinan TG; (2001) 'Novel approaches to the treatment of depression by modulating the hypothalamic-pituitary-adrenal axis'. Human Psychopharmacology, 16 (1):89-93 [Details] | |
| (2001) | 'Selective serotonin reuptake inhibitors and violence: A review of the available evidence' Dinan TG, Walsh MT; (2001) 'Selective serotonin reuptake inhibitors and violence: A review of the available evidence'. 104 (2):84-91 [Details] | |
| (2001) | 'Impact of cortisol on buspirone stimulated prolactin release: a double-blid placebo-controlled study' Dinan, TG, Scott, L, Thakore, J, Naesdal, J, Keeling, PW; (2001) 'Impact of cortisol on buspirone stimulated prolactin release: a double-blid placebo-controlled study'. Psychoneuroendocrinology, 26 (7):751-756 [Details] | |
| (2001) | 'Efficacy and safety of weekly treatment with enteric-coated fluoxetine in patients with major depressive disorder' Dinan TG; (2001) 'Efficacy and safety of weekly treatment with enteric-coated fluoxetine in patients with major depressive disorder'. 62 (Suppl 22):48-52 [Details] | |
| (2001) | 'Clinical recording of risk factors in patients with myocardial infarction: Relationship between psychiatric history and other risk factors' Dinan TG, Prasad S, Lucey J; (2001) 'Clinical recording of risk factors in patients with myocardial infarction: Relationship between psychiatric history and other risk factors'. Irish Medical Journal, 94 (3):88-90 [Details] | |
| (2001) | 'Glucocorticoids and cognitive function: from physiology to pathophysiology' Jamieson K, Dinan TG; (2001) 'Glucocorticoids and cognitive function: from physiology to pathophysiology'. Human Psychopharmacology, 16 (4):293-302 [Details] | |
| (2001) | 'A double-blind placebo-controlled study of buspirone-stimulated prolactin release in non-ulcer dyspepsia - are central serotoninergic responses enhanced?' Dinan TG, Mahmud N, Rathore O, Thakore J, Scott LV, Carr, Naesdal J, O'Morain CA, Keeling PWN; (2001) 'A double-blind placebo-controlled study of buspirone-stimulated prolactin release in non-ulcer dyspepsia - are central serotoninergic responses enhanced?'. Alimentary Pharmacol &Therapeutics, 15 (10):1613-1618 [Details] |
Conference Publications
| Year | Publication | |
|---|---|---|
| (2010) | Digestive Disease Week O'Malley, D; Liston, M; Dinan, TG; Cryan, JF; Hyland, NP (2010) CRF1 receptor-dependent activation of submucosal neurones by colonic supernatants from maternally separated rats Digestive Disease Week [Details] | |
| (2009) | Digestive Disease Week Julio-Pieper M, Hyland NP, Cryan JF, Dinan TG; (2009) Group-III Metabotropic Glutamate Receptors Are Expressed in Rodent Colon: A Role in Cholinergically Induced Electrolyte Secretion Digestive Disease Week [Details] | |
| (2009) | Digestive Disease Week McKernan DP, Nolan A, O'Mahony SM, Hyland NP, Brint E, Dinan TG, Cryan JF.; (2009) Toll-Like Receptor mRNA Expression Is Selectively Increased in the Colonic Mucosa of Two Animal Models of Chronic Stress: Relevance to Irritable Bowel Syndrome Digestive Disease Week [Details] | |
| (2009) | Digestive Disease Week Hyland NP, Bongiovanni C, O'Mahony CM, Fitzgerald P, Dinan TG, Cryan JF; (2009) The Combined Effects of Neonatal Psychological Stress and An Anxious Phenotype On Visceral Hypersensitivity and Colonic Function in Rats Digestive Disease Week [Details] | |
| (2008) | Gastroenterology Hyland NP, O¿Mahony SM, Bulmer DC, Lee K, Dinan TG, Cryan JF.; (2008) Do mast cells contribute to visceral hypersensitivity in adult rats following neonatal psychological stress? Gastroenterology , pp.A552-553 [Details] | |
| (2008) | Neurogastroenterology Motility Hyland NP, O¿Mahony SM, Bulmer DC, Julio-Pieper M, Bongiovanni C, Dinan TG, Cryan JF. ; (2008) Beta3-adrenoceptor mediated secretion and localisation in the submucosal plexus of descending colon from maternally separated animals Neurogastroenterology Motility , pp.1-159 [Details] | |
| (2008) | Digestive Disease Week Hyland NP, Gibney SM, Gosselin RD, Lee K, Dinan TG, Cryan JF (2008) Assessment of colonic secretory function and faecal output in viscerally hypersensitive Wistar Kyoto rats Digestive Disease Week [Details] | |
| (2008) | Neurogastroenterology Motility Hyland NP, O¿ Callaghan K, O¿Malley D, Lee K, Dinan TG, Cryan JF. ; (2008) Differential cholinergic sensitivity in the enteric nervous system in two models of visceral hypersensitivity Neurogastroenterology Motility , pp.1-159 [Details] |
Professional Activities
Conference Contributions
| Year | Publication | |
|---|---|---|
| (2008) | Meeting for Neurogastroenterology and Motility Second Joint International M, Hyland NP, O¿Mahony SM, Bongiovanni C, Julio-Pieper, M, Bulmer DC, Dinan TG, Cryan JF; (2008) Beta3-adrenoceptor mediated secretion and localisation in the submucosal plexus of descending colon from maternally separated animals. [Poster Presentation], Meeting for Neurogastroenterology and Motility Second Joint International M, Lucerne, Switzerland , 01-NOV-08 - 01-NOV-08. [Details] | |
| (2008) | Second Joint International Meeting for Neurogastroenterology and Motility,, Hyland NP, O¿Callaghan K., O¿Malley D, Dinan TG & Cryan JF; (2008) Differential cholinergic sensitivity in the enteric nervous system in two models of visceral hypersensitivity. [Poster Presentation], Second Joint International Meeting for Neurogastroenterology and Motility,, Lucerne, Switzerland , 01-NOV-08 - 01-NOV-08. [Details] | |
| (2008) | Second Joint International Meeting for Neurogastroenterology and Motility,, Clarke G., Fitzgerald P, Cryan JF, Dinan TG; (2008) Increased tryptophan metabolism in irritable bowel syndrome (IBS)¿an immune mediated phenomenon?. [Poster Presentation], Second Joint International Meeting for Neurogastroenterology and Motility,, Lucerne, Switzerland , 01-NOV-08 - 01-NOV-08. [Details] | |
| (2008) | Irish Society of Gastroenterology Spring Conference, Hyland NP, O¿Mahony SM, Bulmer DC, Lee K, Dinan TG & Cryan JF; (2008) Do mast cells contribute to visceral hypersensitivity in adult rats following neonatal psychological stress?. [Poster Presentation], Irish Society of Gastroenterology Spring Conference, Sligo, Ireland , 01-APR-08 - 01-APR-08. [Details] | |
| (2008) | Irish Society of Gastroenterology Spring Conference, Gibney SM, Gosselin RD, O¿Malley DM, Dinan TG & Cryan JF; (2008) Imaging distinct patterns of cortical brain activation following colorectal distension in an animal model of Irritable Bowel Syndrome. [Poster Presentation], Irish Society of Gastroenterology Spring Conference, Sligo, Ireland , 01-JAN-08 - 01-JAN-08. [Details] | |
| (2008) | International neuroimmunology symposium, Bravo JA, Dinan TG & Cryan JF; (2008) The effects of the acetylcholinesterase inhibitor pyridostigmine on inflammatory responses in an animal model of irritable bowel syndrome. [Poster Presentation], International neuroimmunology symposium, UCD, Dublin, Ireland , 01-MAR-08 - 01-MAR-08. [Details] | |
| (2008) | Digestive Disease Week, Clarke G, Fitzgerald P, Cassidy E, Cryan JF, Quigley EM, Dinan TG; (2008) Altered kynurenine pathway metabolism in Irritable Bowel Syndrome (IBS)-Evidence of indoleamine 2,3-dioxygenase (IDO) activation in a male cohort. [Poster Presentation], Digestive Disease Week, San Diego, USA , 01-MAY-08 - 01-MAY-08. [Details] | |
| (2008) | Digestive Disease Week, Bulmer DC, O' Mahony, SM, Coelho A-M, Gray K, Taylor CM, Dinan TG, Cryan JF, Lee K, Winchester WJ; (2008) Analgesic effects of 5-HT2B antagonists in pre-clinical models of colorectal pain. [Poster Presentation], Digestive Disease Week, San Diego, USA , 01-JAN-08 - 01-JAN-08. [Details] | |
| (2008) | Digestive Disease Week, Coelho AM, O 'Mahony SM, Taylor CM, Wheeldon A, Fitzgerald P, Dinan T, Cryan JF, Lee K, Winchester WJ.; (2008) Gabapentin reverses colorectal distension-induced visceral pain behaviours in rat models of acute and chronic visceral hypersensitivity. [Poster Presentation], Digestive Disease Week, San Diego, USA , 01-JAN-08 - 01-JAN-08. [Details] | |
| (2008) | Second Joint International Meeting for Neurogastroenterology and Motility, Gibney SM, Gosselin RD, O¿Malley D, Dinan TG & Cryan JF; (2008) Altered colonic rectal distension-induced activation of the prefrontal cortex in two animals models of irritable bowel syndrome (IBS). [Poster Presentation], Second Joint International Meeting for Neurogastroenterology and Motility, Lucerne, Switzerland , 01-NOV-08 - 01-NOV-08. [Details] | |
| (2008) | Irish Society of Gastroenterology Spring Conference, Clarke G, Fitzgerald P, Cassidy E, Cryan JF, Quigley EM, Dinan TG; (2008) Increased tryptophan degradation along the kynurenine pathway in Irritable Bowel Syndrome (IBS)-Evidence of an immune mediated indoleamine 2,3-dioxygenase (IDO) activation in a male cohort. [Poster Presentation], Irish Society of Gastroenterology Spring Conference, Sligo, Ireland , 01-APR-08 - 01-APR-08. [Details] | |
| (2008) | Second Joint International Meeting for Neurogastroenterology and Motility, O¿Mahony SM, Fitzgerald P, Bulmer DC, Coelho AM, Dinan TG & Cryan JF; (2008) Central 5-HT2B receptors modulate visceral hypersensitivity in a genetic model of irritable bowel syndrome. [Poster Presentation], Second Joint International Meeting for Neurogastroenterology and Motility, Lucerne, Switzerland , 01-NOV-08 - 01-NOV-08. [Details] | |
| (2008) | Second Joint International Meeting for Neurogastroenterology and Motility, O¿Malley D, Julio-Pieper M, Dinan TG & Cryan JF; (2008) The effects of stress on colonic morphology in two animal models of irritable bowel syndrome. [Poster Presentation], Second Joint International Meeting for Neurogastroenterology and Motility, Lucerne, Switzerland , 01-NOV-08 - 01-NOV-08. [Details] | |
| (2008) | Second Joint International Meeting for Neurogastroenterology and Motility, O¿Malley D, Julio-Pieper M, Dinan TG & Cryan JF; (2008) CRF receptor expression in the brain and colon of WKY rats following colorectal distension. [Poster Presentation], Second Joint International Meeting for Neurogastroenterology and Motility, Lucerne, Switzerland , 01-NOV-08 - 01-NOV-08. [Details] | |
| (2008) | European-Behavioural-Pharmacology-Society Workshop on Behavioural Genetics and Neuropsychiatric Disorders, Gosselin RD, Gibney S, O'Malley D, Dinan TG & Cryan JF; (2008) Region specific decrease in glial fibrillary acidic protein (GFAP) immunoreactivity in the brain of a genetic rat model of depression. [Poster Presentation], European-Behavioural-Pharmacology-Society Workshop on Behavioural Genetics and Neuropsychiatric Disorders, Cork, Ireland , 01-AUG-08 - 01-AUG-08. [Details] | |
| (2008) | European-Behavioural-Pharmacology-Society Workshop on Behavioural Genetics and Neuropsychiatric Disorders, Clarke G, O'Mahony S, Hyland NP, Dinan TG & Cryan JF; (2008) Beta3 adrenoceptor modulation of visceral pain - A possible role for the kynurenine pathway?. [Poster Presentation], European-Behavioural-Pharmacology-Society Workshop on Behavioural Genetics and Neuropsychiatric Disorders, Cork, Ireland , 01-AUG-08 - 01-AUG-08. [Details] | |
| (2008) | British Association for psychoparmacology, Summer meeting, O¿ Mahony Cliona M, Bravo J, Dinan TG, Cryan JF; (2008) Comparison of stress-induced alterations in hippocampal mGluR7 mRNA in two animal models of depression. [Poster Presentation], British Association for psychoparmacology, Summer meeting, Harrogate, UK , 01-JUL-08 - 01-JUL-08. [Details] | |
| (2008) | All Ireland Schools of Pharmacy Research Conference, Savignac HM, Hyland NP, Dinan TG & Cryan JF (2008) Social stress induces mild colonic damage and altered anti-inflammatory cytokines in the mouse. [Poster Presentation], All Ireland Schools of Pharmacy Research Conference, Cork, Ireland , 01-APR-08 - 01-APR-08. [Details] | |
| (2008) | Digestive Disease Week, Hyland NP, Gibney SM, Gosselin RD, Lee K, Dinan TG & Cryan JF; (2008) Assessment of colonic secretory function and faecal output in viscerally hypersensitive Wistar Kyoto rats. [Poster Presentation], Digestive Disease Week, San Diego, USA , 01-JAN-08 - 01-JAN-08. [Details] | |
| (2007) | Brainstorming session, 20th Congress of European College of Neuropsychopharmacology, Clarke G, Cryan JF, Dinan TG; (2007) An important subplot in the inflammatory theory of depression?. [Poster Presentation], Brainstorming session, 20th Congress of European College of Neuropsychopharmacology, Vienna, Austria , 01-OCT-07 - 01-OCT-07. [Details] | |
| (2007) | The College of Medicine & Health, UCC Joint Health Research Day incorporating Cork University Hospital Research Day, O' Mahony SM, Fitzgerald P, Coehlo A-M, Taylor C, Cryan JF, Dinan TG.; (2007) Visceral hypersensitivity in two potential animal models of Irritable Bowel Syndrome. [Poster Presentation], The College of Medicine & Health, UCC Joint Health Research Day incorporating Cork University Hospital Research Day, Cork, Ireland , 01-JAN-07 - 01-JAN-07. [Details] | |
| (2007) | European Graduate School of Neuroscience (EURON), Browne, CA, O¿Brien, F, Connor TJ, Dinan, TG, & Cryan JF; (2007) Differential LPS-induced cytokine responses in C57BL/6J and BALB/c mice following stress: Relevance to depression. [Poster Presentation], European Graduate School of Neuroscience (EURON), Bad Honnef, Germany , 01-NOV-07 - 01-NOV-07. [Details] | |
| (2007) | The Irish Society of Gastroenterology Winter meeting, Savignac HM, Hyland NP, Dinan TG, Cryan JF ; (2007) Social stress induces mild colonic damage and altered pro- and anti-inflammatory cytokines in the mouse. [Poster Presentation], The Irish Society of Gastroenterology Winter meeting, Clontarf Castle Hotel, Dublin, Ireland , 01-NOV-07 - 01-NOV-07. [Details] | |
| (2007) | European Graduate School of Neuroscience workshop, Clarke G, Barry S, Scully P, Cryan JF, Dinan T; (2007) Simultaneous measurement of tryptophan and it¿s kynurenine pathway metabolites by HPLC: evidence of increased tryptophan degradation in psychosis. [Poster Presentation], European Graduate School of Neuroscience workshop, Bad Honnef, Germany , 01-NOV-07 - 01-NOV-07. [Details] | |
| (2007) | 19th congress of the European College of Neuropharmacology, O' Mahony SM, Clarke G, O' Mahony L, Quigley EMM, Cryan JF, Dinan TG; (2007) Depressive behaviours and alterations in the immune and stress response systems following neonatal maternal separation. [Poster Presentation], 19th congress of the European College of Neuropharmacology, Vienna, Austria , 01-JAN-07 - 01-JAN-07. [Details] | |
| (2007) | Irish Society of Gastroenterology, Winter Meeting, Hyland NP, Dinan TG, Cryan JF; (2007) Stress susceptible Wistar Kyoto rats display altered epithelial cholinergic sensitivity in the distal colon. [Poster Presentation], Irish Society of Gastroenterology, Winter Meeting, Dublin, Ireland , 01-DEC-07 - 01-DEC-07. [Details] | |
| (2006) | 2nd Interdisciplinary research day of the college of medicine and health, O' Mahony Cliona, Daly E, Dinan TG, Cryan JF; (2006) Genetic influence on stress-induced changes in brain activation in the mouse. [Poster Presentation], 2nd Interdisciplinary research day of the college of medicine and health, University College Cork, Ireland , 01-NOV-06 - 01-NOV-06. [Details] | |
| (2006) | Neuroscience Ireland inaugural conference, O' Mahony Cliona, Daly E, Dinan TG, Cryan JF.; (2006) Genetic influence on stress-induced changes in brain activation in the mouse. [Poster Presentation], Neuroscience Ireland inaugural conference, Cork, Ireland , 01-SEP-06 - 01-SEP-06. [Details] |
Contact details
- Professor/Head of Department
- T.Dinan@ucc.ie
- Psychiatry
University College Cork
Cork
Ireland - +353-21-490-3000
- 0214901220