Biography
Professor Barry Plant MD, FRCPI, MFSEM is a Consultant Respiratory Physician, Clinical Lead for Respiratory Medicine and the Director of the Adult CF Centre at Cork University Hospital (CUH)-University College Cork, an executive member of the CF Registry of Ireland, and an executive board member of ECFS. A University College Cork Medical Graduate (Honours), he dual trained in Respiratory and General Medicine in accordance with the Royal College of Physicians of Ireland and subsequently undertook a Fellowship in Pulmonary and Critical Medicine at the University of Washington, Seattle with a special interest in CF, where he remained until securing his current post in 2007. He is the current Chairperson for the Royal College of Physicians of Ireland’s Clinical Advisory Group (CAG) for Cystic Fibrosis, a lead author of “Cystic Fibrosis: A Model of Care for Ireland” NCP CF 2019 and the Adult Chairperson for the CF Covid NCP CF working group 2020. Professor Plant’s research group focuses on translational medicine. In response to the Covid-19 pandemic he and his research group have established the TeCC (Telemedicine, Cystic Fibrosis, Corona-virus) study to enhance CF care. He has previously received research grant support from many funding agencies including coordinating an FP7 award from the EU commission (www.CFAMTTERS.eu) which completed a randomised multi-centre control trial of microbiome-derived antimicrobial treatments versus current empirical therapy. Equally his research group have significant clinical and research experience in the area of CFTR modulation and Aging in CF. His group actively participate in many CF clinical trials and he has been a PI on ‘real-world’ implications of new inhaled antibiotic delivery systems multicentre groups. Recently Professor Plant was a Global PI on a triple therapy CFTR modulator in CF. He has been an invited speaker at a number of meetings including ATS, ERS, ECFC, Australasian CF Society, and an FDA meeting.
Publications
Book Chapters
| Year | Publication | |
|---|---|---|
| (2019) | 'Designing heterogeneous-mHealth apps for Cystic Fibrosis adults' • Vagg, T., Shortt, C., Fleming, C., McCarthy, M., Tabirca, S. and Plant, B.J. (2019) 'Designing heterogeneous-mHealth apps for Cystic Fibrosis adults' In: Dennis Wat and Dilip Nazareth (eds). Cystic Fibrosis-Heterogeneity and Personalized Treatment. London, UK: IntechOpen. [DOI] [Details] | |
| (2016) | 'Long-Term Implications of Antibiotic Use on Gut Health and Microbiota in Populations Including Patients With Cystic Fibrosis' • Deane, J., Rea, M.C., Fouhy, F., Stanton, C., Ross, R.P. and Plant, B.J. (2016) 'Long-Term Implications of Antibiotic Use on Gut Health and Microbiota in Populations Including Patients With Cystic Fibrosis' In: Niall Hyland Catherine Stanton (eds). Gut-Brain Axis. GLobal: Elsevier Academic Press. [DOI] [Details] | |
| (2015) | 'Changing epidemiology: New challenges in CF' Nicholas Simmonds, Barry Plant (2015) 'Changing epidemiology: New challenges in CF' In: Dominique Hubert · Nicholas Simmonds (eds). Living longer with cystic fibrosis. Karup, Denmark: European Cystic Fibrosis Society. [Details] | |
| (2014) | 'Extrapulmonary manifestations of cystic fibrosis' Barry J. Plant and Michael D. Parkins (2014) 'Extrapulmonary manifestations of cystic fibrosis' In: Marcus A. Mall and J. Stuart Elborn (eds). ERS Monograph: Cystic Fibrosis. Wakefield, UK: Charlesworth Press. [DOI] [Details] | |
| (2005) | 'Diffuse Lung Disease: The Treatment of Cryptogenic Fibrosing Alveolitis' Plant, B. and Egan, J. (2005) 'Diffuse Lung Disease: The Treatment of Cryptogenic Fibrosing Alveolitis' In: Peter G. Gibson, Michael Abramson, Richard Wood-Baker, Jimmy Volmink, Michael Hensley, Ulrich Costabel (eds). Evidence‐based Respiratory Medicine. Massachusetts, USA. Oxford, UK. Victoria, Australia: Blackwell Publishing Ltd. [DOI] [Details] |
Peer Reviewed Journals
| Year | Publication | |
|---|---|---|
| (2021) | 'Recurrent asthma exacerbations: Co-existing asthma and common variable immunodeficiency' Ibrahim, H.; Walsh, J.; Casey, D.; Murphy, J.; Plant, Barry J.; O'Leary, Paula; Murphy, Desmond M.; (2021) 'Recurrent asthma exacerbations: Co-existing asthma and common variable immunodeficiency'. The Journal of asthma : official journal of the Association for the Care of Asthma, [DOI] [Full Text] [Details] | |
| (2020) | 'Pulmonary embolism and covid-19' Farrell A.M.;Walsh L.J.;Plant B.J.;Henry M.T.;Kennedy M.P.;Eustace J.E.;Sadlier C.;Crowley M.;Murphy D.M. (2020) 'Pulmonary embolism and covid-19'. Irish medical journal, 113 (8):1-4 [Details] | |
| (2020) | 'Microbial clues lead to a diagnosis of cystic fibrosis in late adulthood' Kerr C.;Morrissy D.;Horgan M.;Plant B.J. (2020) 'Microbial clues lead to a diagnosis of cystic fibrosis in late adulthood'. BMJ case reports, 13 (4) [DOI] [Details] | |
| (2019) | 'CFTR activity is enhanced by the novel corrector GLPG2222, given with and without ivacaftor in two randomized trials' Bell S.;Barry P.;De Boeck K.;Drevinek P.;Elborn J.;Plant B.;Minic P.;Van Braeckel E.;Verhulst S.;Muller K.;Kanters D.;Bellaire S.;de Kock H.;Geller D.;Conrath K.;Van de Steen O.;van der Ent K. (2019) 'CFTR activity is enhanced by the novel corrector GLPG2222, given with and without ivacaftor in two randomized trials'. Journal of Cystic Fibrosis, [DOI] [Details] | |
| (2018) | 'Clinical effectiveness of dual nicotine replacement therapy in planned hospital admissions to an epilepsy monitoring unit: An irish perspective' McGinty, R. N.,Goulding, D. M.,McCarthy, M. J.,Moloney, S. M.,Costello, D. J.,Plant, B. J. (2018) 'Clinical effectiveness of dual nicotine replacement therapy in planned hospital admissions to an epilepsy monitoring unit: An irish perspective'. Nicotine and Tobacco Research, 20 (5):656-658 [DOI] [Details] | |
| (2018) | 'VX-659–Tezacaftor–Ivacaftor in Patients with Cystic Fibrosis and One or Two Phe508del Alleles' Davies, Jane C.; Moskowitz, Samuel M.; Brown, Cynthia; Horsley, Alexander; Mall, Marcus A.; McKone, Edward F.; Plant, Barry J.; Prais, Dario; Ramsey, Bonnie W.; Taylor-Cousar, Jennifer L.; Tullis, Elizabeth; Uluer, Ahmet; McKee, Charlotte M.; Robertson, Sarah; Shilling, Rebecca A.; Simard, Christopher; Van Goor, Fredrick; Waltz, David; Xuan, Fengjuan; Young, Tim; Rowe, Steven M. (2018) 'VX-659–Tezacaftor–Ivacaftor in Patients with Cystic Fibrosis and One or Two Phe508del Alleles'. New England Journal of Medicine, 379 (17):1599-1611 [DOI] [Full Text] [Details] | |
| (2017) | 'A study to assess the prevalence of exercise-induced bronchoconstriction in inter-county hurling' Hunt, E. B., Murphy, B.,Murphy, C.,Crowley, T.,Cronin, O.,Hay, S.,Stack, M.,Bowen, B.,Ronan, N. J.,Greene, E.,Eustace, J. A.,Plant, B. J.,Murphy, D. M. (2017) 'A study to assess the prevalence of exercise-induced bronchoconstriction in inter-county hurling'. Irish Medical Journal, 110 (10) [Full Text] [Details] | |
| (2017) | 'A study to assess the prevalence of exercise-induced bronchoconstriction in inter-county hurling' Hunt E.;Murphy B.;Murphy C.;Crowley T.;Cronin O.;Hay S.;Stack M.;Bowen B.;Ronan N.;Greene E.;Eustace J.;Plant B.;Murphy D. (2017) 'A study to assess the prevalence of exercise-induced bronchoconstriction in inter-county hurling'. Irish medical journal, 110 (10) [Details] | |
| (2017) | 'CORK Study in Cystic Fibrosis: Sustained Improvements in Ultra-Low-Dose Chest CT Scores After CFTR Modulation With Ivacaftor' Ronan, Nicola J.; Einarsson, Gisli G.; Twomey, Maria; Mooney, Denver; Mullane, David; Ní Chroinin, Muireann; O’Callaghan, Grace; Shanahan, Fergus; Murphy, Desmond M.; O’Connor, Owen J.; Shortt, Cathy A.; Tunney, Michael M.; Eustace, Joseph A.; Maher, Michael M.; Elborn, J. Stuart; Plant, Barry J. (2017) 'CORK Study in Cystic Fibrosis: Sustained Improvements in Ultra-Low-Dose Chest CT Scores After CFTR Modulation With Ivacaftor'. Chest, [DOI] [Full Text] [Details] | |
| (2017) | 'Current strategies for the long-term assessment, monitoring, and management of cystic fibrosis patients treated with CFTR modulator therapy' Elborn, JS;Davies, J;Mall, MA;Flume, PA;Plant, B (2017) 'Current strategies for the long-term assessment, monitoring, and management of cystic fibrosis patients treated with CFTR modulator therapy'. Journal of Cystic Fibrosis, 16 :163-164 [DOI] [Details] | |
| (2015) | 'Cystic fibrosis transmembrane conductance regulator modulators: The end of the beginning' Barry P.;Ronan N.;Plant B. (2015) 'Cystic fibrosis transmembrane conductance regulator modulators: The end of the beginning'. Seminars In Respiratory and Critical Care Medicine, 36 (2):287-298 [DOI] [Details] | |
| (2015) | 'Indicators of pulmonary exacerbation in cystic fibrosis: A Delphi survey of patients and health professionals' McCourt, F;O'Neill, B;Logan, I;Abbott, J;Plant, B;McCrum-Gardner, E;McKeown, S;Elbom, JS;Bradley, JM (2015) 'Indicators of pulmonary exacerbation in cystic fibrosis: A Delphi survey of patients and health professionals'. Journal of Cystic Fibrosis, 14 :90-96 [DOI] [Details] | |
| (2014) | 'A 76 year old female diagnosed with cystic fibrosis' O’brien M.;Murphy D.;Plant B. (2014) 'A 76 year old female diagnosed with cystic fibrosis'. Irish medical journal, 107 (8) [Details] | |
| (2014) | 'Long-term safety and efficacy of ivacaftor in patients with cystic fibrosis who have the Gly551Asp-CFTR mutation: a phase 3, open-label extension study (PERSIST)' McKone, EF;Borowitz, D;Drevinek, P;Griese, M;Konstan, MW;Wainwright, C;Ratjen, F;Sermet-Gaudelus, I;Plant, B;Munck, A;Jiang, Y;Gilmartin, G;Davies, JC (2014) 'Long-term safety and efficacy of ivacaftor in patients with cystic fibrosis who have the Gly551Asp-CFTR mutation: a phase 3, open-label extension study (PERSIST)'. Lancet Respiratory Medicine, 2 :902-910 [DOI] [Details] | |
| (2012) | 'Radiologic Imaging in Cystic Fibrosis Cumulative Effective Dose and Changing Trends Over 2 Decades' O'Connell, O. J.,McWilliams, S.,McGarrigle, A.,O'Connor, O. J.,Shanahan, F.,Mullane, D.,Eustace, J.,Maher, M. M.,Plant, B. J. (2012) 'Radiologic Imaging in Cystic Fibrosis Cumulative Effective Dose and Changing Trends Over 2 Decades'. Chest, 141 (66):1575-15831575 [Details] | |
| (2012) | 'Radiologic imaging in cystic fibrosis: cumulative effective dose and changing trends over 2 decades' O'Connell, O. J.,McWilliams, S.,McGarrigle, A.,O'Connor, O. J.,Shanahan, F.,Mullane, D.,Eustace, J.,Maher, M. M.,Plant, B. J. (2012) 'Radiologic imaging in cystic fibrosis: cumulative effective dose and changing trends over 2 decades'. Chest, 141 (66):1575-1583 [Details] | |
| (2011) | 'Radiological imaging in cystic fibrosis; cumulative effective dose and changing trends over 2 decades' O’ Connell, O. J.*, McWilliams, S., McGarigle, A. M., O’ Connor, O. J., Shanahan, F., Mullane, D., Eustace, J., Maher, M. M. and Plant, B. J. (2011) 'Radiological imaging in cystic fibrosis; cumulative effective dose and changing trends over 2 decades'. Chest, [Details] | |
| (2011) | 'Brachial neuritis masquerading as acute coronary syndrome' Dineen, J,Saidha, S,McNamara, B,Plant, B,Ryan, AM (2011) 'Brachial neuritis masquerading as acute coronary syndrome'. Irish Journal of Medical Science, 180 :291-294 [DOI] [Details] | |
| (2011) | 'Association of cigarette smoking with drug use and risk taking behaviour in Irish teenagers' O’ Cathail, S. M., O’ Connell, O. J., Long, N., Morgan, M., Eustace, J. A., Plant, B. J. and Hourihane, J. O. (2011) 'Association of cigarette smoking with drug use and risk taking behaviour in Irish teenagers'. Addictive Behaviour, 36 (5):547-50 [Details] | |
| (2011) | 'Brachial neuritis masquerading as acute coronary syndrome' Dineen, J.,Saidha, S.,McNamara, B.,Plant, B.,Ryan, A. M. (2011) 'Brachial neuritis masquerading as acute coronary syndrome'. Irish Journal of Medical Science, 180 (1):291-294 [DOI] [Details] | |
| (2011) | 'Association of cigarette smoking with drug use and risk taking behaviour in Irish teenagers' O'Cathail, S. M.,O'Connell, O. J.,Long, N.,Morgan, M.,Eustace, J. A.,Plant, B. J.,Hourihane, J. O. (2011) 'Association of cigarette smoking with drug use and risk taking behaviour in Irish teenagers'. Addict Behav, 36 (55):547-50547 [Details] | |
| (2011) | 'Nebulised hypertonic saline via positive expiratory pressure versus via jet nebuliser in patients with severe cystic fibrosis' O’ Connell, O. J., O’ Farrell, C., Harrison, M. J., Eustace, J. A., Henry, M. T and Plant, B. J. (2011) 'Nebulised hypertonic saline via positive expiratory pressure versus via jet nebuliser in patients with severe cystic fibrosis'. Respiratory Care, 56 (60):771-775 [Details] | |
| (2010) | 'A CF patient with progressive proteinuric renal disease: A CF-specific nodular glomerulosclerosis?' O'Connell O.;Magee C.;Fitzgerald B.;Burke L.;Plant W.;Plant B. (2010) 'A CF patient with progressive proteinuric renal disease: A CF-specific nodular glomerulosclerosis?'. NDT plus, 3 (4):354-356 [DOI] [Details] | |
| (2010) | 'Exercise-induced bronchoconstriction and exercise testing in an international rugby union team' Falvey, E. C.,McCarthy, C.,O'Connor, T. M.,Shanahan, F.,Molloy, M. G.,Plant, B. J. (2010) 'Exercise-induced bronchoconstriction and exercise testing in an international rugby union team'. Thorax, 65 (99):843-844843 [Details] | |
| (2010) | 'Radiological Imaging in Cystic Fibrosis and Associated Radiation Dose Exposure' O'Connell, O. J.,McWilliams, S.,McGarrigle, A.,O'Connor, O.,Shanahan, F.,Mullane, D.,Eustace, J.,Maher, M.,Plant, B. (2010) 'Radiological Imaging in Cystic Fibrosis and Associated Radiation Dose Exposure'. Pediatric Pulmonology, :374-374374 [Details] | |
| (2008) | 'Exercise-Induced Bronchoconstriction and Asthma after Field-Testing in an International Rugby Union Team' Falvey, E. C.,McCarthy, C.,O'Connor, T. M.,Shanahan, F.,Molloy, M. G.,Plant, B. J. (2008) 'Exercise-Induced Bronchoconstriction and Asthma after Field-Testing in an International Rugby Union Team'. Thorax, 63 [Details] | |
| (2011) | 'Brachial neuritis masquerading as acute coronary syndrome' Dineen J, Saidha S, McNamara B, Plant B, Ryan AM (2011) 'Brachial neuritis masquerading as acute coronary syndrome'. Irish Journal of Medical Science, 180 (1):291-294 [DOI] [Details] | |
| (2011) | 'Association of cigarette smoking with drug use and risk taking behaviour in Irish teenagers' O'Cathail, S. M. and O'Connell, O. J. and Long, N. and Morgan, M. and Eustace, J. A. and Plant, B. J. and Hourihane, J. O' B. (2011) 'Association of cigarette smoking with drug use and risk taking behaviour in Irish teenagers'. Addictive Behaviors, 36 (5):547-550 [Details] | |
| (2011) | 'Nebulized hypertonic saline via positive expiratory pressure versus via jet nebulizer in patients with severe cystic fibrosis' O'Connell, O. J.,O'Farrell, C.,Harrison, M. J.,Eustace, J. A.,Henry, M. T.,Plant, B. J. (2011) 'Nebulized hypertonic saline via positive expiratory pressure versus via jet nebulizer in patients with severe cystic fibrosis'. Respir Care, 56 (66):771-5771 [Details] |
Conference Publications
| Year | Publication | |
|---|---|---|
| (2019) | NEW TECHNOLOGIES AND REDESIGNING LEARNING SPACES, VOL I Vagg, T;Tabirca, S;Shortt, C;Fleming, C;Plant, B (2019) Improving Patient Education and the Transition Process Using Virtual Reality NEW TECHNOLOGIES AND REDESIGNING LEARNING SPACES, VOL I , pp.523-526 [DOI] [Details] | |
| (2018) | Proceedings - IEEE Symposium on Computer-Based Medical Systems Vagg T.;Tan Y.;Shortt C.;Hickey C.;Plant B.;Tabirca S. (2018) MHealth and Serious Game Analytics for Cystic Fibrosis Adults Proceedings - IEEE Symposium on Computer-Based Medical Systems , pp.100-105 [DOI] [Details] | |
| (2017) | Journal of Cystic Fibrosis Elborn J.;Davies J.;Mall M.;Flume P.;Plant B. (2017) Current strategies for the long-term assessment, monitoring, and management of cystic fibrosis patients treated with CFTR modulator therapy Journal of Cystic Fibrosis , pp.163-164 [DOI] [Details] | |
| (2016) | ACM International Conference Proceeding Series Tan Y.;Tabirca S.;Vagg T.;Plant B. (2016) Using a mobile game application to monitor well-being data for patients with cystic fibrosis ACM International Conference Proceeding Series , pp.195-198 [DOI] [Details] | |
| (2016) | ACM International Conference Proceeding Series Vagg T.;Plant B.;Tabirca S. (2016) A general mHealth design pipeline ACM International Conference Proceeding Series , pp.190-194 [DOI] [Details] | |
| (2015) | RETHINKING EDUCATION BY LEVERAGING THE ELEARNING PILLAR OF THE DIGITAL AGENDA FOR EUROPE!, VOL. I Vagg, T;Tabirca, S;Plant, B;Eustace, J (2015) INTERACTIVE VISUALISER WITH AUDIO FOR CYSTIC FIBROSIS EDUCATION RETHINKING EDUCATION BY LEVERAGING THE ELEARNING PILLAR OF THE DIGITAL AGENDA FOR EUROPE!, VOL. I , pp.305-310 [DOI] [Details] | |
| (2014) | Chest Barry P.;Plant B.;Nair A.;Bicknell S.;Simmonds N.;Bell N.;Shafi N.;Daniels T.;Shelmerdine S.;Felton I.;Gunaratnam C.;Jones A.;Horsley A. (2014) Eff ects of Ivacaft or in Patients with Cystic Fibrosis Who Carry the G551D mutation and have severe lung disease Chest , pp.152-158 [DOI] [Details] | |
| (2012) | National Conference 2012 Kennedy, B.,Kennedy, M. P.,Plant, B. J.,Henry, M. T.,O'Driscoll, M.,Maher, M.,Nally, K.,Shanahan, F.,Curran, D. R.,O'Connor, T. M. (2012) Bone Marrow and Peripheral Blood Derived CD14(+) Cells as Agents of Tissue Remodelling in Idiopathic Pulmonary Fibrosis National Conference 2012 [Details] | |
| (2010) | Radiological imaging in cystic fibrosis and associated radiation dose exposure O'Connell, OJ,McWilliams, S,McGarrigle, A,O'Connor, O,Shanahan, F,Mullane, D,Eustace, J,Maher, M,Plant, B (2010) PEDIATRIC PULMONOLOGY Radiological imaging in cystic fibrosis and associated radiation dose exposure , pp.374-374 [Full Text] [Details] |
Published Letters
| Year | Publication | |
|---|---|---|
| (2018) | Overexpression of RANK and M-CSFR in Monocytes of G551D-Bearing Patients with Cystic Fibrosis. Velard, F;Jourdain, ML;Abdallah, D;Jacquot, J;Ronan, N;McCarthy, Y;Flanagan, E;Plant, B (2018) Overexpression of RANK and M-CSFR in Monocytes of G551D-Bearing Patients with Cystic Fibrosis. NEW YORK: Published Letters [DOI] [Details] |
Reviews
| Year | Publication | |
|---|---|---|
| (2018) | ECFS best practice guidelines: the 2018 revision. Castellani, C;Duff, AJA;Bell, SC;Heijerman, HGM;Munck, A;Ratjen, F;Sermet-Gaudelus, I;Southern, KW;Barben, J;Flume, PA;Hodkova, P;Kashirskaya, N;Kirszenbaum, MN;Madge, S;Oxley, H;Plant, B;Schwarzenberg, SJ;Smyth, AR;Taccetti, G;Wagner, TOF;Wolfe, SP;Drevinek, P (2018) ECFS best practice guidelines: the 2018 revision. AMSTERDAM: Reviews [DOI] [Details] |
Professional Activities
Professional Associations
| Association | Function | From / To | |
|---|---|---|---|
| Vertex Innovation Research Awards Steering committee | Member | / | |
| Royal College of Physicians - Clinical Advisory Group | Chair Person | / | |
| National Clinical Program | Board Member | / | |
| European Cystic Fibrosis society (ECFS) | Executive Board Member | / | |
| Irish Thoracic Society | Member | / | |
| Science Foundation Ireland | Member | / | |
| Association of Physicians Great Britain and Ireland | Member | / | |
| APC Microbiome | Funded Investigator | / | |
| Royal College of Physicians | Fellow | / | |
| European Respiratory Society (ERS) | Member | / | |
| HRB-CRF-C, University College Cork | Deputy Director | / |