Professor Caplice Centre for Research in Vascular Biology research programme is addressing fundamental questions in vascular stem cell biology, atherosclerosis and vascular remodeling with emphasis on translation of ideas to the clinical cardiology arena in areas of novel diagnostics and therapeutics in the field of stem cells, gene delivery and tissue engineering.
Biography
Professor Noel Caplice is Professor of Cardiovascular Sciences in the Department of Medicine and Director of the Centre for Research in Vascular Biology at University College Cork. He is also a Consultant Cardiologist at Cork University Hospital. He previously held professional positions in pharmacology and medicine at the Mayo Clinic, Rochester, Minnesota, USA, where he was an interventional cardiologist and directed the Vascular Stem Cell Laboratory.Professor Caplice Centre for Research in Vascular Biology research programme is addressing fundamental questions in vascular stem cell biology, atherosclerosis and vascular remodeling with emphasis on translation of ideas to the clinical cardiology arena in areas of novel diagnostics and therapeutics in the field of stem cells, gene delivery and tissue engineering.
Research Interests
1. Detection of human smooth muscle progenitor cells in blood and human atherosclerotic plaque.
2.Determinatiing the cardiac repair potential of specific cytoprotective factors in models of myocardilal infarction
3. Realtime tracking of stem cells in vivo and evaluation of paracrine cardiomyocyte repair effects of progenitor cells
4. Biology of vacsular progenitor cells and smooth muscle progenitor cells in animal models of atheroaclerosis, graft engineering, remodeling after stent injury and myocardial infarction
Publications
Book Chapters
| Year | Publication | |
|---|---|---|
| (2011) | 'Key Role of Angiogenic Control in Recovery from Ischaemic Heart Disease’' John F O’Sullivan, Anne-Laure Leblond, Noel M Caplice. M Slevin (2011) 'Key Role of Angiogenic Control in Recovery from Ischaemic Heart Disease’' In: Therapeutic Angiogenesis for Vascular Diseases. DOI 10.1007/978-90-481-9495-7_12: Springer Science-Business Media B.V. [Details] | |
| (2011) | 'A Key Role of Angiogenic Control in Recovery from Ischaemic Heart Disease' O'Sullivan, JF;Leblond, AL;Caplice, NM (2011) 'A Key Role of Angiogenic Control in Recovery from Ischaemic Heart Disease' In: THERAPEUTIC ANGIOGENESIS FOR VASCULAR DISEASES. BERLIN: SPRINGER-VERLAG BERLIN. [DOI] [Details] | |
| (2010) | 'Gene transfer for coronary restenosis' Caplice, NM; Simari, RD; (2010) 'Gene transfer for coronary restenosis' In: Current Review of Interventional Cardiology.4th Ed. Philadelphia: Current Medicine Inc. [Details] | |
| (2010) | 'New biologic developments in stents and grafts' Caplice., NM; (2010) 'New biologic developments in stents and grafts' In: Textbook of Interventional Cardiology. Armonk, NY: Futura Publishing. [Details] | |
| (2010) | 'A key role for angiogenesis in recovery from myocardial infarction' O'Sullivan, JF; Leblond, AL; Caplice, NM; (2010) 'A key role for angiogenesis in recovery from myocardial infarction' In: Therapeutic Angiogenesis for Vascular Diseases. New York: Springer-Verlag. [Details] | |
| (2006) | 'Safety Concerns in the Cell Therapy Era' Deb A, Caplice NM. ; (2006) 'Safety Concerns in the Cell Therapy Era' In: Textbook of Cellular Therapies in Cardiovascular Diseases. USA: Eds: Willerson & Perin. [Details] | |
| (1999) | 'Adenoviral vectors for cardiovascular diseases' Caplice NM, O'Brien T, Simari RD; (1999) 'Adenoviral vectors for cardiovascular diseases' In: Adenoviruses:Basic biology to gene therapy. Austin, TX: RG Landes. [Details] | |
| (1995) | 'Rabbit models of atherosclerosis and restenosis' Caplice NM, Fennessy PA, Manderson JA, Campbell GR, Campbell JH; (1995) 'Rabbit models of atherosclerosis and restenosis' In: Atherosclerosis. Amsterdam: Elsevier. [Details] |
Peer Reviewed Journals
| Year | Publication | |
|---|---|---|
| (2022) | 'High-Fidelity Porcine Models of Metabolic Syndrome: A Contemporary Synthesis' Cluzel GL;Ryan PM;Herisson FM;Caplice NM; (2022) 'High-Fidelity Porcine Models of Metabolic Syndrome: A Contemporary Synthesis'. American Journal of Physiology (Endocrinology and Metabolism), [DOI] [Details] | |
| (2021) | 'A state-of-the-art review of the current role of cardioprotective techniques in cardiac transplantation' Cullen PP;Tsui SS;Caplice NM;Hinchion JA; (2021) 'A state-of-the-art review of the current role of cardioprotective techniques in cardiac transplantation'. Interactive Cardiovascular and Thoracic Surgery, 32 (5) [DOI] [Details] | |
| (2021) | 'Exploring the Gut Microbiota and Cardiovascular Disease' Murphy K;O'Donovan AN;Caplice NM;Ross RP;Stanton C; (2021) 'Exploring the Gut Microbiota and Cardiovascular Disease'. Metabolites, 11 (8) [DOI] [Details] | |
| (2021) | 'Metabolic syndrome and synbiotic targeting of the gut microbiome' Nunez-Sanchez, MA;Herisson, FM;Cluzel, GL;Caplice, NM (2021) 'Metabolic syndrome and synbiotic targeting of the gut microbiome'. Current Opinion In Food Science, 41 :60-69 [DOI] [Details] | |
| (2020) | 'Is adipose tissue a reservoir for viral spread, immune activation and cytokine amplification in COVID-19?' Ryan, Paul MacDaragh; Caplice, Noel M. (2020) 'Is adipose tissue a reservoir for viral spread, immune activation and cytokine amplification in COVID-19?'. Obesity (Silver Spring, Md.), [DOI] [Full Text] [Details] | |
| (2020) | 'Vascular Tissue Engineering: Advanced Techniques and Gene Editing in Stem Cells for Graft Generation' Chen, SG;Ugwu, F;Li, WC;Caplice, NM;Petcu, E;Yip, SP;Huang, CL (2020) 'Vascular Tissue Engineering: Advanced Techniques and Gene Editing in Stem Cells for Graft Generation'. Tissue Engineering Part B-Reviews, [DOI] [Details] | |
| (2020) | 'Gut microbiome of a porcine model of metabolic syndrome and HF-pEF' O'Donovan A.N.;Herisson F.M.;Fouhy F.;Ryan P.M.;Whelan D.;Johnson C.N.;Cluzel G.;Ross R.P.;Stanton C.;Caplice N.M. (2020) 'Gut microbiome of a porcine model of metabolic syndrome and HF-pEF'. American Journal of Physiology - Heart and Circulatory Physiology, 318 (3):H590-H603 [DOI] [Details] | |
| (2020) | 'Mesenchymal stromal cell derived CCL2 is required for accelerated wound healing' Whelan D.;Caplice N.;Clover A. (2020) 'Mesenchymal stromal cell derived CCL2 is required for accelerated wound healing'. Scientific Reports, 10 (1) [DOI] [Details] | |
| (2020) | 'COVID-19 and relative angiotensin-converting enzyme 2 deficiency: role in disease severity and therapeutic response' Ryan PM;Caplice N; (2020) 'COVID-19 and relative angiotensin-converting enzyme 2 deficiency: role in disease severity and therapeutic response'. Open Heart, 7 (1) [DOI] [Details] | |
| (2019) | 'Lactobacillus mucosae DPC 6426 as a bile-modifying and immunomodulatory microbe' Ryan, PM;Stolte, EH;London, LEE;Wells, JM;Long, SL;Joyce, SA;Gahan, CGM;Fitzgerald, GF;Ross, RP;Caplice, NM;Stanton, C (2019) 'Lactobacillus mucosae DPC 6426 as a bile-modifying and immunomodulatory microbe'. BMC Microbiology, 19 [DOI] [Details] | |
| (2018) | 'Randomized placebo controlled trial evaluating the safety and efficacy of single low dose intracoronary insulin like growth factor following percutaneous coronary intervention in acute myocardial infarction (RESUS-AMI)' Caplice, Noel M.; DeVoe, Mary C.; Choi, Janet; Dahly, Darren; Murphy, Theodore; Spitzer, Ernest; Van Geuns, Robert; Maher, Michael M.; Tuite, David; Kerins, David M.; Ali, Mohammed T.; Kalyar, Imtiaz; Fahy, Eoin F.; Khider, Wisam; Kelly, Peter; Kearney, Peter P.; Curtin, Ronan J.; O’Shea, Conor; Vaughan, Carl J.; Eustace, Joseph A.; McFadden, Eugene P. (2018) 'Randomized placebo controlled trial evaluating the safety and efficacy of single low dose intracoronary insulin like growth factor following percutaneous coronary intervention in acute myocardial infarction (RESUS-AMI)'. American Heart Journal, [DOI] [Full Text] [Details] | |
| (2017) | 'Microbiome and metabolome modifying effects of several cardiovascular disease interventions in apo-E-/- mice' Ryan, Paul M.; London, Lis E. E.; Bjorndahl, Trent C.; Mandal, Rupasri; Murphy, Kiera; Fitzgerald, Gerald F.; Shanahan, Fergus; Ross, R. Paul; Wishart, David S.; Caplice, Noel M.; Stanton, Catherine (2017) 'Microbiome and metabolome modifying effects of several cardiovascular disease interventions in apo-E-/- mice'. Microbiome, 5 (30):1-13 [DOI] [Full Text] [Details] | |
| (2017) | 'Selective M2 Macrophage Depletion Leads to Prolonged Inflammation in Surgical Wounds' Klinkert, K;Whelan, D;Clover, AJP;Leblond, AL;Kumar, AHS;Caplice, NM (2017) 'Selective M2 Macrophage Depletion Leads to Prolonged Inflammation in Surgical Wounds'. European Surgical Research, 58 :109-120 [DOI] [Details] | |
| (2016) | 'A Novel Selectable Islet 1 Positive Progenitor Cell Reprogrammed to Expandable and Functional Smooth Muscle Cells' Turner EC;Huang CL;Sawhney N;Govindarajan K;Clover AJ;Martin K;Browne TC;Whelan D;Kumar AH;Mackrill JJ;Wang S;Schmeckpeper J;Stocca A;Pierce WG;Leblond AL;Cai L;O'Sullivan DM;Buneker CK;Choi J;MacSharry J;Ikeda Y;Russell SJ;Caplice NM; (2016) 'A Novel Selectable Islet 1 Positive Progenitor Cell Reprogrammed to Expandable and Functional Smooth Muscle Cells'. Stem Cells (Dayton, Ohio), 34 (5) [DOI] [Details] | |
| (2015) | 'Functional food addressing heart health: do we have to target the gut microbiota?' Ryan PM;Ross RP;Fitzgerald GF;Caplice NM;Stanton C; (2015) 'Functional food addressing heart health: do we have to target the gut microbiota?'. Current Opinion In Clinical Nutrition And Metabolic Care, 18 (6) [DOI] [Details] | |
| (2015) | 'Allogeneic mesenchymal stem cells, but not culture modified monocytes, improve burn wound healing' Clover, AJP,Kumar, AHS,Isakson, M,Whelan, D,Stocca, A,Gleeson, BM,Caplice, NM (2015) 'Allogeneic mesenchymal stem cells, but not culture modified monocytes, improve burn wound healing'. Journal of The International Society For Burn Injuries, 41 :548-557 [DOI] [Details] | |
| (2015) | 'Systemic and Cardiac Depletion of M2 Macrophage through CSF-1R Signaling Inhibition Alters Cardiac Function Post Myocardial Infarction' Leblond, AL,Klinkert, K,Martin, K,Turner, EC,Kumar, AH,Browne, T,Caplice, NM (2015) 'Systemic and Cardiac Depletion of M2 Macrophage through CSF-1R Signaling Inhibition Alters Cardiac Function Post Myocardial Infarction'. Plos One, 10 [DOI] [Details] | |
| (2015) | 'Bone Marrow-Derived Mesenchymal Stem Cells Have Innate Procoagulant Activity and Cause Microvascular Obstruction Following Intracoronary Delivery: Amelioration by Antithrombin Therapy' Gleeson, BM;Martin, K;Ali, MT;Kumar, AHS;Pillai, MGK;Kumar, SPG;O'Sullivan, JF;Whelan, D;Stocca, A;Khider, W;Barry, FP;O'Brien, T;Caplice, NM (2015) 'Bone Marrow-Derived Mesenchymal Stem Cells Have Innate Procoagulant Activity and Cause Microvascular Obstruction Following Intracoronary Delivery: Amelioration by Antithrombin Therapy'. Stem Cells (Dayton, Ohio), 33 :2726-2737 [DOI] [Details] | |
| (2015) | 'A novel CX(3)CR1 antagonist eluting stent reduces stenosis by targeting inflammation' Ali, MT,Martin, K,Kumar, AHS,Cavallin, E,Pierrou, S,Gleeson, BM,McPheat, WL,Turner, EC,Huang, CL,Khider, W,Vaughan, C,Caplice, NM (2015) 'A novel CX(3)CR1 antagonist eluting stent reduces stenosis by targeting inflammation'. Biomaterials, 69 :22-29 [DOI] [Details] | |
| (2015) | 'Genome Sequence of the Heteropolysaccharide-Producing Strain Lactobacillus mucosae DPC 6426' Ryan, PM;Guinane, CM;London, LEE;Kelleher, PR;Fitzgerald, GF;Caplice, NM;Ross, RP;Stanton, C (2015) 'Genome Sequence of the Heteropolysaccharide-Producing Strain Lactobacillus mucosae DPC 6426'. Microbiology Resource Announcements, 3 [DOI] [Details] | |
| (2015) | 'Sugar-coated: Exopolysaccharide producing lactic acid bacteria for food and human health applications' Ryan P.;Ross R.;Fitzgerald G.;Caplice N.;Stanton C. (2015) 'Sugar-coated: Exopolysaccharide producing lactic acid bacteria for food and human health applications'. Food & Function, 6 (3):679-693 [DOI] [Details] | |
| (2015) | 'Acute STEMI in the setting of a single coronary artery anomaly' McCarthy C.;Khider W.;Caplice N. (2015) 'Acute STEMI in the setting of a single coronary artery anomaly'. BMJ case reports, 2015 [DOI] [Details] | |
| (2015) | 'Synthetic Chemically Modified mRNA-Based Delivery of Cytoprotective Factor Promotes Early Cardiomyocyte Survival Post-Acute Myocardial Infarction' Huang, C. L.,Leblond, A. L.,Turner, E. C.,Kumar, A. H.,Martin, K.,Whelan, D.,O'Sullivan, D. M.,Caplice, N. M. (2015) 'Synthetic Chemically Modified mRNA-Based Delivery of Cytoprotective Factor Promotes Early Cardiomyocyte Survival Post-Acute Myocardial Infarction'. Mol Pharmmol Pharm, [Details] | |
| (2015) | 'Synthetic Chemically Modified mRNA-Based Delivery of Cytoprotective Factor Promotes Early Cardiomyocyte Survival Post-Acute Myocardial Infarction' Huang, CL;Leblond, AL;Turner, EC;Kumar, AH;Martin, K;Whelan, D;O'Sullivan, DM;Caplice, NM (2015) 'Synthetic Chemically Modified mRNA-Based Delivery of Cytoprotective Factor Promotes Early Cardiomyocyte Survival Post-Acute Myocardial Infarction'. Molecular Pharmaceutics, 12 :991-996 [DOI] [Details] | |
| (2014) | 'Intravascular cell delivery device for therapeutic VEGF-induced angiogenesis in chronic vascular occlusion' Kumar, AHS,Martin, K,Doyle, B,Huang, CL,Pillai, GKM,Ali, MT,Skelding, KA,Wang, SH,Gleeson, BM,Jahangeer, S,Ritman, EL,Russell, SJ,Caplice, NM (2014) 'Intravascular cell delivery device for therapeutic VEGF-induced angiogenesis in chronic vascular occlusion'. Biomaterials, 35 :9012-9022 [DOI] [Details] | |
| (2014) | 'Regenerative Approaches to Post-Myocardial Infarction Heart Failure' Martin, K,Huang, CL,Caplice, NM (2014) 'Regenerative Approaches to Post-Myocardial Infarction Heart Failure'. Current Pharmaceutical Design, 20 :1930-1940 [Details] | |
| (2014) | 'Exopolysaccharide-Producing Probiotic Lactobacilli Reduce Serum Cholesterol and Modify Enteric Microbiota in ApoE-Deficient Mice' London, L. E.,Kumar, A. H.,Wall, R.,Casey, P. G.,O'Sullivan, O.,Shanahan, F.,Hill, C.,Cotter, P. D.,Fitzgerald, G. F.,Ross, R. P.,Caplice, N. M.,Stanton, C. (2014) 'Exopolysaccharide-Producing Probiotic Lactobacilli Reduce Serum Cholesterol and Modify Enteric Microbiota in ApoE-Deficient Mice'. Journal of Nutrition, 144 (12):1956-1962 [Details] | |
| (2014) | 'Role of the Gut in Modulating Lipoprotein Metabolism' Hennessy, AA;Ross, RP;Fitzgerald, GF;Caplice, N;Stanton, C (2014) 'Role of the Gut in Modulating Lipoprotein Metabolism'. Current Cardiology Reports, 16 [DOI] [Details] | |
| (2014) | 'Exopolysaccharide-Producing Probiotic Lactobacilli Reduced Serum Cholesterol and Modified Enteric Microbiota in ApoE-Deficient Mice' London LE, Kumar AH, Wall R, Casey PG, O'Sullivan O, Shanahan F, Hill C, Cotter PD, Fitzgerald GF, Ross RP, Caplice NM, Stanton C (2014) 'Exopolysaccharide-Producing Probiotic Lactobacilli Reduced Serum Cholesterol and Modified Enteric Microbiota in ApoE-Deficient Mice'. The Journal of Nutrition, [DOI] [Details] | |
| (2014) | 'Regenerative Approaches to Post-Myocardial Infarction Heart Failure' Martin, K;Huang, CL;Caplice, NM (2014) 'Regenerative Approaches to Post-Myocardial Infarction Heart Failure'. Current Pharmaceutical Design, 20 :1930-1940 [Details] | |
| (2014) | 'Exopolysaccharide-Producing Probiotic Lactobacilli Reduce Serum Cholesterol and Modify Enteric Microbiota in ApoE-Deficient Mice' London, LEE;Kumar, AHS;Wall, R;Casey, PG;O'Sullivan, O;Shanahan, F;Hill, C;Cotter, PD;Fitzgerald, GF;Ross, RP;Caplice, NM;Stanton, C (2014) 'Exopolysaccharide-Producing Probiotic Lactobacilli Reduce Serum Cholesterol and Modify Enteric Microbiota in ApoE-Deficient Mice'. Journal of Nutrition, 144 :1956-1962 [DOI] [Details] | |
| (2014) | 'Regenerative Approaches to Post-Myocardial Infarction Heart Failure' Martin K, Huang CL, Caplice NM (2014) 'Regenerative Approaches to Post-Myocardial Infarction Heart Failure'. Current Pharmaceutical Design, 20 :1930-1940 [Details] | |
| (2014) | 'Intravascular cell-delivery device for therapeutic VEGF-induced angiogenesis in chronic vascular occlusion' Kumar AH, Martin K, Doyle B, Huang CL, Krishnan G, Ali MT, Skelding KA, Wang S, Gleeson BM, Jahangeer S, Ritman EL, Russell SJ, Caplice NM. (2014) 'Intravascular cell-delivery device for therapeutic VEGF-induced angiogenesis in chronic vascular occlusion'. Biomaterials, [Details] | |
| (2013) | 'Multidetector computed tomography accurately defines infarct size, but not microvascular obstruction after myocardial infarction' O'Sullivan, J. F.,Leblond, A. L.,O'Dea, J.,Hristova, I.,Kumar, S.,Martin, K.,Kumar, A. H.,Caplice, N. M. (2013) 'Multidetector computed tomography accurately defines infarct size, but not microvascular obstruction after myocardial infarction'. J Am Coll Cardiol, 61 (22):208-10 [Details] | |
| (2013) | 'Role of CX3CR1 receptor in monocyte/macrophage driven neovascularization' Kumar AH, Martin K, Turner EC, Buneker CK, Dorgham K, Deterre P, Caplice NM (2013) 'Role of CX3CR1 receptor in monocyte/macrophage driven neovascularization'. Plos One, 8 (2) [DOI] [Details] | |
| (2013) | 'Differential Endothelial Coverage, Response to Injury and Neointimal Integration of CX3CR1/Smooth Muscle-Like Cells after Carotid or Femoral Arterial Injury' Martin, K;Kumar, AHS;Klinkert, K;Caplice, NM (2013) 'Differential Endothelial Coverage, Response to Injury and Neointimal Integration of CX3CR1/Smooth Muscle-Like Cells after Carotid or Femoral Arterial Injury'. Journal of Vascular Research, 50 :200-209 [DOI] [Details] | |
| (2013) | 'Differential Endothelial Coverage, Response to Injury and Neointimal Integration of CX3CR1/Smooth Muscle-Like Cells after Carotid or Femoral Arterial Injury' Martin K, Kumar AH, Klinkert K, Caplice NM (2013) 'Differential Endothelial Coverage, Response to Injury and Neointimal Integration of CX3CR1/Smooth Muscle-Like Cells after Carotid or Femoral Arterial Injury'. Journal of Vascular Research, 50 (3):200-209 [DOI] [Details] | |
| (2013) | 'Multidetector Computed Tomography Accurately Defines Infarct Size, But Not Microvascular Obstruction After Myocardial Infarction' O'Sullivan, JF,Leblond, AL,O'Dea, J,Hristova, I,Kumar, S,Martin, K,Kumar, AHS,Caplice, NM (2013) 'Multidetector Computed Tomography Accurately Defines Infarct Size, But Not Microvascular Obstruction After Myocardial Infarction'. Journal of The American College of Cardiology, 61 :208-210 [DOI] [Details] | |
| (2013) | 'Multidetector computed tomography accurately defines infarct size, but not microvascular obstruction after myocardial infarction' O'Sullivan JF, Leblond AL, O'Dea J, Hristova I, Kumar S, Martin K, Kumar AH, Caplice NM (2013) 'Multidetector computed tomography accurately defines infarct size, but not microvascular obstruction after myocardial infarction'. Journal of The American College of Cardiology, 61 (2):208-210 [DOI] [Details] | |
| (2013) | 'Role of CX(3)CR1 Receptor in Monocyte/Macrophage Driven Neovascularization' Kumar, AHS,Martin, K,Turner, EC,Buneker, CK,Dorgham, K,Deterre, P,Caplice, NM (2013) 'Role of CX(3)CR1 Receptor in Monocyte/Macrophage Driven Neovascularization'. Plos One, 8 [DOI] [Details] | |
| (2013) | 'Differential Endothelial Coverage, Response to Injury and Neointimal Integration of CX3CR1/Smooth Muscle-Like Cells after Carotid or Femoral Arterial Injury' Martin, K.,Kumar, A. H.,Klinkert, K.,Caplice, N. M. (2013) 'Differential Endothelial Coverage, Response to Injury and Neointimal Integration of CX3CR1/Smooth Muscle-Like Cells after Carotid or Femoral Arterial Injury'. J Vasc Res, 50 (33):200-209 [Details] | |
| (2013) | 'Regenerative Approaches to Post-Myocardial Infarction Heart Failure' Martin, K.,Huang, C.L.,Caplice, N.M. (2013) 'Regenerative Approaches to Post-Myocardial Infarction Heart Failure'. Curr Pharm Design, [Details] | |
| (2013) | 'Identification of a Klf4-dependent upstream repressor region mediating transcriptional regulation of the myocardin gene in human smooth muscle cells' Turner, EC,Huang, CL,Govindarajan, K,Caplice, NM (2013) 'Identification of a Klf4-dependent upstream repressor region mediating transcriptional regulation of the myocardin gene in human smooth muscle cells'. Biochimica Et Biophysica Acta-Gene Regulatory Mechanisms, 1829 :1191-1201 [DOI] [Details] | |
| (2013) | 'Potent endothelial progenitor cell-conditioned media-related anti-apoptotic, cardiotrophic, and pro-angiogenic effects post-myocardial infarction are mediated by insulin-like growth factor-1' Hynes, B,Kumar, AHS,O'Sullivan, J,Buneker, CK,Leblond, AL,Weiss, S,Schmeckpeper, J,Martin, K,Caplice, NM (2013) 'Potent endothelial progenitor cell-conditioned media-related anti-apoptotic, cardiotrophic, and pro-angiogenic effects post-myocardial infarction are mediated by insulin-like growth factor-1'. European Heart Journal, 34 :782-789 [DOI] [Details] | |
| (2013) | 'Role of CX(3)CR1 receptor in monocyte/macrophage driven neovascularization' Kumar, A. H.,Martin, K.,Turner, E. C.,Buneker, C. K.,Dorgham, K.,Deterre, P.,Caplice, N. M. (2013) 'Role of CX(3)CR1 receptor in monocyte/macrophage driven neovascularization'. PLoS One, 8 (22) [Details] | |
| (2013) | 'Pregnancy-specific glycoproteins bind integrin αIIbβ3 and inhibit the platelet-fibrinogen interaction' Shanley DK, Kiely PA, Golla K, Allen S, Martin K, O'Riordan RT, Ball M, Aplin JD, Singer BB, Caplice N, Moran N, Moore T (2013) 'Pregnancy-specific glycoproteins bind integrin αIIbβ3 and inhibit the platelet-fibrinogen interaction'. Plos One, 8 (2) [DOI] [Details] | |
| (2013) | 'Identification of a Klf4-dependent upstream repressor region mediating transcriptional regulation of the myocardin gene in human smooth muscle cells' Turner EC, Huang CL, Govindarajan K, Caplice NM (2013) 'Identification of a Klf4-dependent upstream repressor region mediating transcriptional regulation of the myocardin gene in human smooth muscle cells'. Biochimica Et Biophysica Acta, 1829 (11):1191-1201 [DOI] [Details] | |
| (2012) | 'Calcium signalling in adult endothelial outgrowth cells' Pierce, WG;Zanette, C;Caplice, NM;Mackrill, JJ (2012) 'Calcium signalling in adult endothelial outgrowth cells'. Biochemical and Biophysical Research Communications, 417 :358-363 [DOI] [Details] | |
| (2011) | 'Potent endothelial progenitor cell-conditioned media-related anti-apoptotic, cardiotrophic, and pro-angiogenic effects post-myocardial infarction are mediated by insulin-like growth factor-1' Hynes B, Kumar AH, O'Sullivan J, Klein Buneker C, Leblond AL, Weiss S, Schmeckpeper J, Martin K, Caplice NM (2011) 'Potent endothelial progenitor cell-conditioned media-related anti-apoptotic, cardiotrophic, and pro-angiogenic effects post-myocardial infarction are mediated by insulin-like growth factor-1'. European Heart Journal, [DOI] [Details] | |
| (2011) | 'Calcium signalling in adult endothelial outgrowth cells' Pierce WG, Zanette C, Caplice NM, Mackrill JJ (2011) 'Calcium signalling in adult endothelial outgrowth cells'. Biochemical and Biophysical Research Communications, [DOI] [Details] | |
| (2011) | 'Role of vessel wall and bone marrow syndecan-4 in newintimal hyperplasia: the plot thickens' Caplice NM (2011) 'Role of vessel wall and bone marrow syndecan-4 in newintimal hyperplasia: the plot thickens'. Arteriosclerosis Thrombosis and Vascular Biology, [Details] | |
| (2011) | 'Improved protocol for processing stented porcine coronary arteries for immunostaining' Kumar AH, McCauley SD, Hynes BG, O'Dea J, Caplice NM; (2011) 'Improved protocol for processing stented porcine coronary arteries for immunostaining'. Journal of Molecular Histology, 42 (2):187-193 [Details] | |
| (2011) | 'Pleiotropic role for monocyte C-fms protein in response to vascular injury: Potential therapeutic target' Metharom P, Martin K, Kumar AH, Sawhney N, Cronin MF, McCarthy DG, Maguire AR, Caplice NM; (2011) 'Pleiotropic role for monocyte C-fms protein in response to vascular injury: Potential therapeutic target'. Atherosclerosis, 216 (1):74-82 [Details] | |
| (2011) | 'Potent long-term cardioprotective effects of single low-dose insulin-like growth factor-1 treatment postmyocardial infarction' O'Sullivan JF, Leblond AL, Kelly G, Kumar AH, Metharom P, Büneker CK, Alizadeh-Vikali N, Hristova I, Hynes BG, O'Connor R, Caplice NM; (2011) 'Potent long-term cardioprotective effects of single low-dose insulin-like growth factor-1 treatment postmyocardial infarction'. Circulation-Cardiovascular Interventions, 4 (4):327-335 [Details] | |
| (2011) | 'Deficiency of CX3CR1 delays burn wound healing and is associated with reduced myeloid cell recruitment and decreased sub-dermal angiogenesis' Clover AJ, Kumar AH, Caplice NM; (2011) 'Deficiency of CX3CR1 delays burn wound healing and is associated with reduced myeloid cell recruitment and decreased sub-dermal angiogenesis'. Burns : journal of the International Society for Burn Injuries, [Details] | |
| (2011) | 'Improved protocol for processing stented porcine coronary arteries for immunostaining' Kumar, AHS,McCauley, SD,Hynes, BG,O'Dea, J,Caplice, NM; (2011) 'Improved protocol for processing stented porcine coronary arteries for immunostaining'. Rna-A Publication of The Rna Society, 42 :187-193 [DOI] [Details] | |
| (2011) | 'Pleiotropic role for monocyte C-fms protein in response to vascular injury: potential therapeutic target' Metharom P, Martin K, Kumar AH, Sawhney N, Cronin MF, McCarthy DG, Maguire AR, Caplice NM (2011) 'Pleiotropic role for monocyte C-fms protein in response to vascular injury: potential therapeutic target'. Atherosclerosis, 216 (1):74-82 [DOI] [Details] | |
| (2011) | 'New therapeutic potential of microRNA treatment to target vulnerable atherosclerotic lesions and plaque rupture' Martin K, O'Sullivan JF, Caplice NM (2011) 'New therapeutic potential of microRNA treatment to target vulnerable atherosclerotic lesions and plaque rupture'. Current Opinion In Cardiology, 26 (6):569-575 [DOI] [Details] | |
| (2011) | 'Microribonucleic acids for prevention of plaque rupture and in-stent restenosis: a finger in the dam' O'Sullivan JF, Martin K, Caplice NM (2011) 'Microribonucleic acids for prevention of plaque rupture and in-stent restenosis: a finger in the dam'. Journal of The American College of Cardiology, 57 (4):383-389 [DOI] [Details] | |
| (2011) | 'Deficiency of CX3CR1 delays burn wound healing and is associated with reduced myeloid cell recruitment and decreased sub-dermal angiogenesis' Clover, AJP;Kumar, AHS;Caplice, NM (2011) 'Deficiency of CX3CR1 delays burn wound healing and is associated with reduced myeloid cell recruitment and decreased sub-dermal angiogenesis'. Burns, 37 :1386-1393 [DOI] [Details] | |
| (2011) | 'Pro-Osteoclastogenic Phenotype of Monocyte Subsets in Active Ra Characterized by Downregulation of Surface Cx3cr1' Murphy, G.,Ryan, J.,Harney, S.,Shanahan, F.,Caplice, N.,Molloy, M. (2011) 'Pro-Osteoclastogenic Phenotype of Monocyte Subsets in Active Ra Characterized by Downregulation of Surface Cx3cr1'. Rheumatology (Oxford), 50 :51-5251 [Details] | |
| (2011) | 'Cx3cr1 Deficiency Results in Protection from Collagen-Induced Arthritis in a Transgenic Mouse Model' Murphy, G.,Kumar, A.,Shanahan, F.,Harney, S.,Molloy, M.,Caplice, N. (2011) 'Cx3cr1 Deficiency Results in Protection from Collagen-Induced Arthritis in a Transgenic Mouse Model'. Rheumatology (Oxford), 50 :75-7675 [Details] | |
| (2011) | 'Downregulation of the chemokine receptor CX3CR1 in active RA associated with a pro-osteoclastogenic phenotype' Murphy, G.,Ryan, J.,Harney, S.,Shanahan, F.,Molloy, M.,Caplice, N. (2011) 'Downregulation of the chemokine receptor CX3CR1 in active RA associated with a pro-osteoclastogenic phenotype'. Ir J Med Sci, 180 [Details] | |
| (2011) | 'Protection from collagen-induced arthritis in a CX3CR1 deficient mouse strain' Murphy, G.,Kumar, A.,Shanahan, F.,Harney, S.,Molloy, M.,Caplice, N. (2011) 'Protection from collagen-induced arthritis in a CX3CR1 deficient mouse strain'. Ir J Med Sci, 180 [Details] | |
| (2011) | 'Potent endothelial progenitor cell-conditioned media-related anti-apoptotic, cardiotrophic, and pro-angiogenic effects post-myocardial infarction are mediated by insulin-like growth factor-1' Hynes, B.,Kumar, A. H.,O'Sullivan, J.,Klein Buneker, C.,Leblond, A. L.,Weiss, S.,Schmeckpeper, J.,Martin, K.,Caplice, N. M. (2011) 'Potent endothelial progenitor cell-conditioned media-related anti-apoptotic, cardiotrophic, and pro-angiogenic effects post-myocardial infarction are mediated by insulin-like growth factor-1'. Eur Heart J, [Details] | |
| (2011) | 'New therapeutic potential of microRNA treatment to target vulnerable atherosclerotic lesions and plaque rupture' Martin, K.,O'Sullivan, J. F.,Caplice, N. M. (2011) 'New therapeutic potential of microRNA treatment to target vulnerable atherosclerotic lesions and plaque rupture'. Curr Opin Cardiol, 26 (66):569-75 [Details] | |
| (2011) | 'Microribonucleic acids for prevention of plaque rupture and in-stent restenosis a finger in the dam' O'Sullivan, J. F.,Martin, K.,Caplice, N. M. (2011) 'Microribonucleic acids for prevention of plaque rupture and in-stent restenosis a finger in the dam'. J Am Coll Cardiol, 57 (44):383-9 [Details] | |
| (2011) | 'Improved protocol for processing stented porcine coronary arteries for immunostaining' Kumar, AHS;McCauley, SD;Hynes, BG;O'Dea, J;Caplice, NM (2011) 'Improved protocol for processing stented porcine coronary arteries for immunostaining'. Journal of Molecular Histology, 42 :187-193 [DOI] [Details] | |
| (2010) | 'Clinical Potential of Adult Vascular Progenitor Cells' Kumar, AHS;Caplice, NM (2010) 'Clinical Potential of Adult Vascular Progenitor Cells'. Arteriosclerosis Thrombosis and Vascular Biology, 30 :1080-1087 [DOI] [Details] | |
| (2010) | 'Clinical Potential of Adult Vascular Progenitor Cells' Kumar, AHS; Caplice, NM; (2010) 'Clinical Potential of Adult Vascular Progenitor Cells'. Arteriosclerosis Thrombosis and Vascular Biology, 30 :1080-1087 [DOI] [Details] | |
| (2010) | 'A Specific Subset of Mouse Bone Marrow Cells Has Smooth Muscle Cell Differentiation Capacity-Brief Report' Metharom, P;Kumar, AHS;Weiss, S;Caplice, NM (2010) 'A Specific Subset of Mouse Bone Marrow Cells Has Smooth Muscle Cell Differentiation Capacity-Brief Report'. Arteriosclerosis Thrombosis and Vascular Biology, 30 :533-357 [DOI] [Details] | |
| (2010) | 'Bone marrow-derived CX3CR1 progenitors contribute to neointimal smooth muscle cells via fractalkine CX3CR1 interaction' Kumar, A. H.,Metharom, P.,Schmeckpeper, J.,Weiss, S.,Martin, K.,Caplice, N. M. (2010) 'Bone marrow-derived CX3CR1 progenitors contribute to neointimal smooth muscle cells via fractalkine CX3CR1 interaction'. FASEB J, 24 (11):81-92 [Details] | |
| (2010) | 'Contrast enhanced ultrasound and the enigma of plaque neovascularisation' Caplice, NM; Martin K; (2010) 'Contrast enhanced ultrasound and the enigma of plaque neovascularisation'. Journal of the American College of Cardiology, 12 :1273-1275 [Details] | |
| (2010) | 'Bone marrow-derived CX3CR1 progenitors contribute to neointimal smooth muscle cells via fractalkine CX3CR1 interaction' Kumar AH, Metharom P, Schmeckpeper J, Weiss S, Martin K, Caplice NM (2010) 'Bone marrow-derived CX3CR1 progenitors contribute to neointimal smooth muscle cells via fractalkine CX3CR1 interaction'. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 24 (1):81-92 [DOI] [Details] | |
| (2010) | 'Contrast-enhanced ultrasound and the enigma of plaque neovascularization' Caplice, N. M.,Martin, K. (2010) 'Contrast-enhanced ultrasound and the enigma of plaque neovascularization'. JACC Cardiovasc Imaging, 3 (1212):1273-51273 [Details] | |
| (2010) | 'Bone marrow-derived CX(3)CR1 progenitors contribute to neointimal smooth muscle cells via fractalkine CX(3)CR1 interaction' Kumar, AHS; Metharom, P; Schmeckpeper, J; Weiss, S; Martin, K; Caplice, NM; (2010) 'Bone marrow-derived CX(3)CR1 progenitors contribute to neointimal smooth muscle cells via fractalkine CX(3)CR1 interaction'. The Faseb Journal, 24 :81-92 [DOI] [Details] | |
| (2009) | 'Myeloid Lineage of Human Endothelial Outgrowth Cells Circulating in Blood and Vasculogenic Endothelial-Like Cells in the Diseased Vessel Wall' Liu, CS;Wang, SH;Metharom, P;Caplice, NM (2009) 'Myeloid Lineage of Human Endothelial Outgrowth Cells Circulating in Blood and Vasculogenic Endothelial-Like Cells in the Diseased Vessel Wall'. Journal of Vascular Research, 46 :581-591 [DOI] [Details] | |
| (2009) | 'Lentiviral tracking of vascular differentiation in bone marrow progenitor cells' Schmeckpeper, J,Ikeda, Y,Kumar, AHS,Metharom, P,Russell, SJ,Caplice, NM; (2009) 'Lentiviral tracking of vascular differentiation in bone marrow progenitor cells'. Differentiation; Research In Biological Diversity, 78 :169-176 [DOI] [Details] | |
| (2009) | 'Bone marrow mononuclear stem cells in treatment of myocardial infarction' Leblond AL, O'Sullivan J, Caplice N.; (2009) 'Bone marrow mononuclear stem cells in treatment of myocardial infarction'. Stem Cells and cloning, 2 :11-19 [Details] | |
| (2009) | 'Myeloid lineage of human endothelial outgrowth cells circulating in blood and vasculogenic endothelial-like cells in the diseased vessel wall' Liu C, Wang S, Metharom P, Caplice NM; (2009) 'Myeloid lineage of human endothelial outgrowth cells circulating in blood and vasculogenic endothelial-like cells in the diseased vessel wall'. Journal of Vascular Research, 46 :581-591 [Details] | |
| (2009) | 'Thrombin stimulates smooth muscle cell differentiation from peripheral blood mononuclear cells via protease-activated receptor-1, RhoA, and myocardin' Martin K, Weiss S, Metharom P, Schmeckpeper J, Hynes B, O'Sullivan J, Caplice N (2009) 'Thrombin stimulates smooth muscle cell differentiation from peripheral blood mononuclear cells via protease-activated receptor-1, RhoA, and myocardin'. Circulation Research, 105 (3):214-218 [DOI] [Details] | |
| (2009) | 'Thrombin stimulates smooth muscle cell differentiation from peripheral blood mononuclear cells via protease-activated receptor-1, RhoA, and myocardin' Martin, K.,Weiss, S.,Metharom, P.,Schmeckpeper, J.,Hynes, B.,O'Sullivan, J.,Caplice, N. (2009) 'Thrombin stimulates smooth muscle cell differentiation from peripheral blood mononuclear cells via protease-activated receptor-1, RhoA, and myocardin'. Circ Res, 105 (33):214-8 [Details] | |
| (2009) | 'Lentiviral tracking of vascular differentiation in bone marrow progenitor cells' Schmeckpeper, J;Ikeda, Y;Kumar, AHS;Metharom, P;Russell, SJ;Caplice, NM (2009) 'Lentiviral tracking of vascular differentiation in bone marrow progenitor cells'. Differentiation, 78 :169-176 [DOI] [Details] | |
| (2008) | 'Myeloid lineage of high proliferative potential human smooth muscle outgrowth cells circulating in blood and vasculogenic smooth muscle-like cells in vivo' Metharom, P;Liu, C;Wang, S;Stalboerger, P;Chen, G;Doyle, B;Ikeda, Y;Caplice, NM (2008) 'Myeloid lineage of high proliferative potential human smooth muscle outgrowth cells circulating in blood and vasculogenic smooth muscle-like cells in vivo'. Atherosclerosis, 198 :29-38 [DOI] [Details] | |
| (2008) | 'Myeoloid lineage of high proliferative potential human smooth muscle outgrowth cells circulating in blood and vasculogenic smooth muscle-like cells in vivo' Metharom P, Liu C, Wang S. Stalboerger P, Chen G, Doyle B, Ikeda Y, Caplice NM ; (2008) 'Myeoloid lineage of high proliferative potential human smooth muscle outgrowth cells circulating in blood and vasculogenic smooth muscle-like cells in vivo'. Atherosclerosis, 198 :29-38 [Details] | |
| (2008) | 'Progenitor Cell Therapy in a Porcine Acute Myocardial Infarction Model Induces Cardiac Hypertrophy, Mediated by Paracrine Secretion of Cardiotrophic Factors Including TGF beta 1' Doyle, B;Sorajja, P;Hynes, B;Kumar, AHS;Araoz, PA;Stalboerger, PG;Miller, D;Reed, C;Schmeckpeper, J;Wang, S;Liu, CS;Terzic, A;Kruger, D;Riederer, S;Caplice, NM (2008) 'Progenitor Cell Therapy in a Porcine Acute Myocardial Infarction Model Induces Cardiac Hypertrophy, Mediated by Paracrine Secretion of Cardiotrophic Factors Including TGF beta 1'. Stem Cells and Development, 17 :941-951 [DOI] [Details] | |
| (2008) | 'Fractalkine in rheumatoid arthritis: a review to date' Murphy G, Caplice N, Molloy M.; (2008) 'Fractalkine in rheumatoid arthritis: a review to date'. Rheumatology, 27 (10):1446-1451 [Details] | |
| (2008) | 'Progenitor cell therapy for acute myocardial infraction induces cardiac hypertrophy, mediated by paracrine seceretion of cardiotrophic factors including TGF β1' Doyle B, Sorajja P, Hynes B, Kumar A, Araoz PA, Stalboerger PS, Miller DV, Reed C,Schmeckpeper, Wang S, Liu C, Terzic A, Kruger D, Reiderer S, Caplice NM.; (2008) 'Progenitor cell therapy for acute myocardial infraction induces cardiac hypertrophy, mediated by paracrine seceretion of cardiotrophic factors including TGF β1'. Stem Cell Development, 17 (5):941-951 [Details] | |
| (2008) | 'Progression of non-culprit stenosis following successful percutaneous intervention' Bunch TJ, Rihal CS, Gumina RJ, Cooper L, Caplice NM. ; (2008) 'Progression of non-culprit stenosis following successful percutaneous intervention'. International Angiology, 59 :236-239 [Details] | |
| (2007) | 'Neoangiogenesis and the presence of progenitor cells in the venous limb of an arteriovenous fistula in the rat' Caplice N.;Wang S.;Tracz M.;Croatt A.;Grande J.;Katusic Z.;Nath K. (2007) 'Neoangiogenesis and the presence of progenitor cells in the venous limb of an arteriovenous fistula in the rat'. American journal of physiology. Renal physiology, 293 (2) [DOI] [Details] | |
| (2007) | 'Clinical trials in stem cell therapy: Pitfalls and lessons for the future' Metharom P.;Doyle B.;Caplice N. (2007) 'Clinical trials in stem cell therapy: Pitfalls and lessons for the future'. Nature Clinical Practice, Cardiovascular Medicine, 4 (SUPPL. 1) [DOI] [Details] | |
| (2007) | 'Plaque neovascularization and antiangiogenic therapy for atherosclerosis' Doyle, B;Caplice, N (2007) 'Plaque neovascularization and antiangiogenic therapy for atherosclerosis'. Journal of The American College of Cardiology, 49 :2073-2080 [Details] | |
| (2007) | 'Infected cell carriers: a new strategy for systemic delievery of oncolytic measles viruses in cancer virotherapy' Iankov ID, Blechacz B, Liu C, Schmeckpeper JD, Tarara JE, Federspiel MJ, Caplice N, Russell SJ. ; (2007) 'Infected cell carriers: a new strategy for systemic delievery of oncolytic measles viruses in cancer virotherapy'. Molecular Therapy, 1 :114-122 [Details] | |
| (2007) | 'Clinical trails in stem cell therapy: pitfalls and lessons for the future' Metharom P, Doyle B, Caplice NM. ; (2007) 'Clinical trails in stem cell therapy: pitfalls and lessons for the future'. Nature Clinical Practice, Cardiovascular Medicine, 1 :S96-S99 [Details] | |
| (2007) | 'Vascular disease: a new progenitor biology' Metharom P, Capice NM. ; (2007) 'Vascular disease: a new progenitor biology'. Current Vascular Pharmacology, 1 :61-68 [Details] | |
| (2007) | 'Plaque neovascularization and antiangiogenic therapy for atherosclerosis' Doyle B, Caplice N. ; (2007) 'Plaque neovascularization and antiangiogenic therapy for atherosclerosis'. Journal of American College of Cardiology, 49 (21):2073-2080 [Details] | |
| (2007) | 'Neoangiogenesis and the presence of progenitor cells in the venous limb of an arteriovenous fistula in the rat' Caplice NM, Wang S, Tracz M, Croatt AJ, Grande JP, Katusic ZS, Nath KA. ; (2007) 'Neoangiogenesis and the presence of progenitor cells in the venous limb of an arteriovenous fistula in the rat'. American Journal of Pysiology: Renal Physiology, 293 (2):F470-F275 [Details] | |
| (2007) | 'Dynamic Tracking During Intracoronary Injection of F-18-Fdg-Labeled Progenitor Cell Therapy For Acute Myocardial Infarction' Doyle, B, Kemp, BJ, Chareonthaitawee, P, Reed, C, Schmeckpeper, J, Sorajja, P, Russell, S, Araoz, P, Riederer, SJ, Caplice, NM; (2007) 'Dynamic Tracking During Intracoronary Injection of F-18-Fdg-Labeled Progenitor Cell Therapy For Acute Myocardial Infarction'. Journal of Nuclear Medicine, 48 (10):1708-1714 [DOI] [Details] | |
| (2007) | 'Dynamic tracking during intracoronary injection of F-18-FDG-labeled progenitor cell therapy for acute myocardial infarction' Doyle, B;Kemp, BJ;Chareonthaitawee, P;Reed, C;Schmeckpeper, J;Sorajja, P;Russell, S;Araoz, P;Riederer, SJ;Caplice, NM (2007) 'Dynamic tracking during intracoronary injection of F-18-FDG-labeled progenitor cell therapy for acute myocardial infarction'. Journal of Nuclear Medicine, 48 :1708-1714 [DOI] [Details] | |
| (2007) | 'Plaque Neovascularization and Antiangiogenic Therapy For Atherosclerosis' Doyle, B, Caplice, N; (2007) 'Plaque Neovascularization and Antiangiogenic Therapy For Atherosclerosis'. Journal of The American College of Cardiology, 49 (21):2073-2080 [Details] | |
| (2006) | 'The future of cell therapy for acute myocardial infarction' Caplice N. (2006) 'The future of cell therapy for acute myocardial infarction'. Nature Clinical Practice, Cardiovascular Medicine, 3 (SUPPL. 1) [DOI] [Details] | |
| (2006) | 'Endothelial progenitor cells' Doyle, B,Metharom, P,Caplice, NM; (2006) 'Endothelial progenitor cells'. Journal of Endothelial Cell Research, 13 :403-410 [DOI] [Details] | |
| (2006) | 'Endothelial progenitor cells' Doyle, B;Metharom, P;Caplice, NM (2006) 'Endothelial progenitor cells'. Endothelium-Journal Of Endothelial Cell Research, 13 :403-410 [DOI] [Details] | |
| (2006) | 'Targeting angiogenesis versus myogenesis with cardiac cell therapy' Doyle B, Caplice NM. ; (2006) 'Targeting angiogenesis versus myogenesis with cardiac cell therapy'. Experimental Review in Cardiovascular Therapy, 4 :745-753 [Details] | |
| (2006) | 'Endothelial Progenitor Cells' Doyle, B, Metharom, P, Caplice, NM; (2006) 'Endothelial Progenitor Cells'. Journal of Endothelial Cell Research, 13 (6):403-410 [DOI] [Details] | |
| (2006) | 'Nephrogenic fibrosing dermopathy and high dose erythropoietin therapy' Swaminathan S, Ahmed I, McCarthy JT, Albright RC, Pittlekow MR, Caplice NM, Griffin MD, Leung N. ; (2006) 'Nephrogenic fibrosing dermopathy and high dose erythropoietin therapy'. Annals of Internal Medicine, 145 :234-235 [Details] | |
| (2006) | 'Functional and structural remodeling of myocardial microvasculature in early experimental hypertension' Rodriguez-Porcel M, Zhu X, Chade A, Amores-Arriaga B, Caplice N, Ritman E, Lerman A, Lerman L. ; (2006) 'Functional and structural remodeling of myocardial microvasculature in early experimental hypertension'. Americal Journal of Physiolory:Heart and Circulatory Physiology, 290 :978-984 [Details] | |
| (2006) | 'The impact of TGF-beta 1 on AV node conduction modification by injected autologous fibroblasts in the canine heart' Bunch TJ, Mahaptra S, Bruce GK, Johnson SB, Miller DV, Wang XL, Lee HC, Caplice N, Packer DL.; (2006) 'The impact of TGF-beta 1 on AV node conduction modification by injected autologous fibroblasts in the canine heart'. Circulation, 113 :2485-2494 [Details] | |
| (2006) | 'Functional and structural remodeling of myocardial microvasculature in early experimental hypertension' Rodriguez-Porcel M, Zhu X, Chade A, Amores-Arriaga B, Caplice N, Ritman E, Lerman A, Lerman L. ; (2006) 'Functional and structural remodeling of myocardial microvasculature in early experimental hypertension'. American Journal of Physiology: Heart and Circulatory Physiology, 290 :978-984 [Details] | |
| (2006) | 'PAF receptor is preferentially expressed in a distinct synthetic phenotype of smooth muscle cells cloned from human internal thoracic artery. Functional implications in cell migration' Stengel D, O¿Neil C, Brocheriou I, Karabina SA, Caplice NM, Pickering JG, Ninio E. ; (2006) 'PAF receptor is preferentially expressed in a distinct synthetic phenotype of smooth muscle cells cloned from human internal thoracic artery. Functional implications in cell migration'. Biochem Biophys Res Commun, 346 :693-699 [Details] | |
| (2006) | 'Future cell therapy for myocardial infarction' Caplice NM. ; (2006) 'Future cell therapy for myocardial infarction'. Nature Clinical Practice, Cardiovascular Medicine, Supplement1 :129-132 [Details] | |
| (2005) | 'Pro-apoptotic, antimigratory, antiproliferative ande anti-angiogenic effects of commercial CRP on various human endothelial cell types in vitro: implications of contaminating presence of sodium azide in commercial preparation' Liu C, Wang S, Deb A, Nath K, Katusic Z, McConnell J, Caplice NM. ; (2005) 'Pro-apoptotic, antimigratory, antiproliferative ande anti-angiogenic effects of commercial CRP on various human endothelial cell types in vitro: implications of contaminating presence of sodium azide in commercial preparation'. Circulation Research, 97 :135-143 [Details] | |
| (2005) | 'TFPI antigen and activity levels in patients with asymptomatic atherosclerosis and target organ acute and chronic complications' Novo G, Caplice N, Tantillo, Bonura F, Simari R, Novo S. ; (2005) 'TFPI antigen and activity levels in patients with asymptomatic atherosclerosis and target organ acute and chronic complications'. International Angiology, 24 :266-371 [Details] | |
| (2005) | 'Cyclosporine decreases vascular progenitor cell number following cardiac transplantation and attenuates progenitor cell function' Davies WR, Wang S, Oi K, Caplice NM, McGregor CGA. ; (2005) 'Cyclosporine decreases vascular progenitor cell number following cardiac transplantation and attenuates progenitor cell function'. Journal of Heart and Lung Transplantation, 24 :1868-1877 [Details] | |
| (2005) | 'Leptin receptor and functional effects of leptin in human endothelial progenitor cells' Wolk R, Deb A, Caplice NM, Somers VK. ; (2005) 'Leptin receptor and functional effects of leptin in human endothelial progenitor cells'. Atherosclerosis, 183 :131-139 [Details] | |
| (2005) | 'TFPI antigen and activity levels in patients with asymptomatic atherosclerosis and target organ acute and chronic complications. Int Angiol' Novo G, Caplice N, Tantillo R, Bonura F, Simari R, Novo S.; (2005) 'TFPI antigen and activity levels in patients with asymptomatic atherosclerosis and target organ acute and chronic complications. Int Angiol'. International Angiology, 24 :366-371 [Details] | |
| (2005) | 'MCP-1 is upregulated in unstressed and stressed HO-1 knockout mice: pathophysiologic correlates' Pittock ST, Norby SM, Grande JP, Croatt AJ, Bren GD, Badley AD, Caplice NM, Griffin MD, Nath KA. ; (2005) 'MCP-1 is upregulated in unstressed and stressed HO-1 knockout mice: pathophysiologic correlates'. Kidney International, 68 :611-622 [Details] | |
| (2005) | 'A new source of endothelial progenitor cells ¿ vascular biology redefined' Doyle B, Caplice NM.; (2005) 'A new source of endothelial progenitor cells ¿ vascular biology redefined'. Trends in Biotechnology, 23 :444-446 [Details] | |
| (2005) | 'Unresolved questions, changing definitions and novel paradigms for defining endothelial progenitor cells' Ingram DA, Caplice NM, Yoder MC. ; (2005) 'Unresolved questions, changing definitions and novel paradigms for defining endothelial progenitor cells'. Blood, 106 :1525-1531 [Details] | |
| (2005) | 'Transgenic sickle mice are markedly sensitive to renal ischemia-reperfusion injury' Nath KA, Croatt T, Grande JP, Hebbel RP, Caplice NM, Katusic ZS. ; (2005) 'Transgenic sickle mice are markedly sensitive to renal ischemia-reperfusion injury'. American Journal of Pathology, 166 :963-972 [Details] | |
| (2005) | 'Letter regarding article by Rotmans et al, In vivo cell seeding with anti-CD34 antibodies successfully accelerates endothelialization but stimulates intimal hyperplasia in porcine arteriovenous expanded polytetrafluoroethylene grafts' Doyle B, Caplice N. .; (2005) 'Letter regarding article by Rotmans et al, In vivo cell seeding with anti-CD34 antibodies successfully accelerates endothelialization but stimulates intimal hyperplasia in porcine arteriovenous expanded polytetrafluoroethylene grafts'. Circulation, 112 (24):e359-e359 [Details] | |
| (2005) | 'Graft endothelialization and intimal hyperplasia' Doyle B, Caplice NM. ; (2005) 'Graft endothelialization and intimal hyperplasia'. Circulation, 112 :359-360 [Details] | |
| (2005) | 'Cell therapy for cardiovascular diseases. What cell, when and to whom?' Caplice NM, Alegria J,. ; (2005) 'Cell therapy for cardiovascular diseases. What cell, when and to whom?'. Nature Clinical Practice, Cardiovascular Medicine, 2 :37-43 [Details] | |
| (2005) | 'Bone marrow derived smooth muscle precursors in human heart valves' Deb A, Wang S, Caplice NM. ; (2005) 'Bone marrow derived smooth muscle precursors in human heart valves'. Journal of Heart valve Disease, 14 :674-678 [Details] | |
| (2005) | 'Vascular progenitor cells: origin and mechanisms of mobilization, differentiation, integration and vasculogenesis' Doyle B, Caplice NM. ; (2005) 'Vascular progenitor cells: origin and mechanisms of mobilization, differentiation, integration and vasculogenesis'. Stem Cell Development, 14 :122-139 [Details] | |
| (2004) | 'Elevated expression of manganese superoxide dismutase is a critical protective mechanism against oxidative stress in human endothelial progenitor cells' He T, Peterson T, Holmuhamedov E, Terzic A, Caplice NM, Oberley LW, Katusic ZS. ; (2004) 'Elevated expression of manganese superoxide dismutase is a critical protective mechanism against oxidative stress in human endothelial progenitor cells'. Atherosclerosis, Thrombosis and Vascular Biology, 24 :20021-20027 [Details] | |
| (2004) | 'Integrin profile and in vivo homing of human smooth muscle progenitor cells' Deb A, Skelding KA, Wang S, Reeder M, Simper D, Caplice NM. ; (2004) 'Integrin profile and in vivo homing of human smooth muscle progenitor cells'. Circulation, 110 :2673-2677 [Details] | |
| (2004) | 'Transplantation of circulating endothelial progenitor cells restores endothelial function of denuded rabbit carotid arteries' He T, Smith LA, Richardson DM, Harrington S, Nath KA, Caplice NM, Katusic ZS. ; (2004) 'Transplantation of circulating endothelial progenitor cells restores endothelial function of denuded rabbit carotid arteries'. Stroke, 35 :2378-2384 [Details] | |
| (2004) | 'Smooth muscle progenitor cells in vascular disease' Liu C, Nath KA, Katusic ZS.,Caplice NM ; (2004) 'Smooth muscle progenitor cells in vascular disease'. Trends in Cardiovascular Medicine, 14 :288-293 [Details] | |
| (2004) | 'Dog peritoneal and pleural cavities as bioreactors to grow autologous vascular grafts' Chue WL, Campbell GR, Caplice N, Muhammed A, Berry C, Thomas AC, Bennett MB, Campbell JH. ; (2004) 'Dog peritoneal and pleural cavities as bioreactors to grow autologous vascular grafts'. Journal of Vascular Surgery, 39 :859-867 [Details] | |
| (2004) | 'Lipoprotein (a). New insights into mechanisms of atherogenesis and atherothrombosis' Deb A, Caplice NM. ; (2004) 'Lipoprotein (a). New insights into mechanisms of atherogenesis and atherothrombosis'. Clinical Cardiology, 27 :258-264 [Details] | |
| (2004) | 'Fatal coronary artery disease after unrelated donor bone marrow transplantation' Ghobrial IM, Bunch TJ, Caplice NM, Edwards WD, Miller DV, Litzow MR. ; (2004) 'Fatal coronary artery disease after unrelated donor bone marrow transplantation'. Mayo Clinic Proceedings, 79 :403-406 [Details] | |
| (2004) | 'Antioxidant intervention attenuates myocardial neovascularization in hypercholesterolemia' Zhu XY, Rodriguez-Porcel M, Bentley MD, Chade AR, Sica V, Napoli C, Caplice N, Ritman EL, Lerman A, Lerman LO. ; (2004) 'Antioxidant intervention attenuates myocardial neovascularization in hypercholesterolemia'. Circulation, 109 :2109-2115 [Details] | |
| (2004) | 'Myocardial Cell replacement. The science, the clinic and the future' Caplice NM. Deb A. ; (2004) 'Myocardial Cell replacement. The science, the clinic and the future'. Nature Clinical Practice, Cardiovascular Medicine, 1 :90-95 [Details] | |
| (2003) | 'TFPI deficiency enhances neointimal proliferation and formation in a murine model of vascular remodeling' Singh R, Pan S, Mueske C, Witt T, Kleppe L, Peterson T, Caplice NM, Simari RD. ; (2003) 'TFPI deficiency enhances neointimal proliferation and formation in a murine model of vascular remodeling'. Thrombosis and Haemostasis, 89 :747-751 [Details] | |
| (2003) | 'Infectious and ischemic complications from percutaneous closure devices used after vascular access' Boston US, Panneton JM, Hofer JM, Sabater EA, Caplice N, Rowland CM, Noel AA, Bower TC, Cherry Jr KJ, Gloviczki P. ; (2003) 'Infectious and ischemic complications from percutaneous closure devices used after vascular access'. Annals of Vascular Surgery, 17 :66-71 [Details] | |
| (2003) | 'Smooth muscle cells in human coronary atherosclerosis can originate from cells administered at marrow transplantation' Caplice NM Bunch TJ, Stalboerger P,Wang S, Simper D, Miller DV, Russell SJ, Litzow MR, Edwards WD. ; (2003) 'Smooth muscle cells in human coronary atherosclerosis can originate from cells administered at marrow transplantation'. Proceedings of the National Acadamy of Sciences, 100 (8):4754-4759 [Details] | |
| (2003) | 'Bone marrow derived cardiomyocytes are present in adult human heart: A study of gender-mismatched bone marrow transplantation patients' Deb A, Wang S, Skelding K, Miller D, Simper D, Caplice NM.; (2003) 'Bone marrow derived cardiomyocytes are present in adult human heart: A study of gender-mismatched bone marrow transplantation patients'. Circulation, 107 :1247-1249 [Details] | |
| (2003) | 'Stem cells to repair the heart-A clinical perspective' Caplice NM, Gersh BJ. ; (2003) 'Stem cells to repair the heart-A clinical perspective'. Circulation Research, 92 :6-8 [Details] | |
| (2003) | 'Endothelial progenitor cells are decreased in blood of cardiac allograft subjects with vasculopathy and endothelial cells of non-cardiac origin are enriched in transplant atherosclerosis' Simper D, Wang S, Deb A, Holmes DR, McGregor C, Frantz R, Kushwaha S, Caplice NM. ; (2003) 'Endothelial progenitor cells are decreased in blood of cardiac allograft subjects with vasculopathy and endothelial cells of non-cardiac origin are enriched in transplant atherosclerosis'. Circulation, 108 :143-149 [Details] | |
| (2003) | 'Nitric Oxide synthase gene transfer as a tool to study biology of endothelial cells' Katusic Z, Caplice NM, Nath KA. ; (2003) 'Nitric Oxide synthase gene transfer as a tool to study biology of endothelial cells'. Arteriosclerosis Thrombosis and Vascular Biology, 23 :1990-1994 [Details] | |
| (2003) | 'Quantifying Chimeric Cardiomyocytes-' Deb A, Wang S, Skelding K, Simper D, Caplice NM. ; (2003) 'Quantifying Chimeric Cardiomyocytes-'. Circulation, 108 :60-61 [Details] | |
| (2002) | 'A tissue-engineered stent for cell based vascular gene transfer' Panetta C, Miyauchi K, Berry D, Simari RD, Holmes D, Schwartz R, Caplice NM. ; (2002) 'A tissue-engineered stent for cell based vascular gene transfer'. Human Gene Therapy, 13 :433-441 [Details] | |
| (2002) | 'Smooth muscle progenitor cells in human blood' Simper D, Stalboerger P, Panetta C, Wang S, Caplice NM. ; (2002) 'Smooth muscle progenitor cells in human blood'. Circulation, 106 :1199-1204 [Details] | |
| (2001) | 'Biologic alternatives to stents and grafts' Caplice NM. ; (2001) 'Biologic alternatives to stents and grafts'. Current Cardiology Report, 3 :17-21 [Details] | |
| (2001) | 'Remnant lipoproteins induce endothelial plasminogen activator inhibitor-1' Sawka A, Singh RJ, Hiddinga HJ, McConnell JP, Eberhardt NL, Caplice NM, O¿Brien T. ; (2001) 'Remnant lipoproteins induce endothelial plasminogen activator inhibitor-1'. Biochemical Biophysical Research Communications, 285 :15-19 [Details] | |
| (2001) | 'Role for tissue factor pathway in murine model of vascular remodeling' Singh R, Pan S, Mueske C, Witt T, Kleppe L, Peterson T, Slobodova A, Chang J, Caplice NM, Simari RD. ; (2001) 'Role for tissue factor pathway in murine model of vascular remodeling'. Circulation Research, 89 :71-76 [Details] | |
| (2001) | 'Cell proliferation in carcinoid valve disease: a mechanism for serotonin effects' Rajamannan N, Caplice N, Anthikad F, Sebo T, Orszulak TA, Edwards WD, Tajik AJ, Schwartz RS. ; (2001) 'Cell proliferation in carcinoid valve disease: a mechanism for serotonin effects'. Journal of Heart valve Disease, 10 :827-831 [Details] | |
| (2001) | 'Lipoprotein (a) binds and inactivates tissue factor pathway inhibitor: A novel link between lipoproteins and thrombosis' Caplice NM, Peterson TF, Kleppe LS, Mueske CS, Kostner GM, Broze GJ, Simari RD. ; (2001) 'Lipoprotein (a) binds and inactivates tissue factor pathway inhibitor: A novel link between lipoproteins and thrombosis'. Blood, 98 :2980-2987 [Details] | |
| (2001) | 'Plasmin proteolysis of endothelial cell and vessel wall associated tissue factor pathway inhibitor' Stalboerger P, Panetta C, Simari RD, Caplice NM. ; (2001) 'Plasmin proteolysis of endothelial cell and vessel wall associated tissue factor pathway inhibitor'. Thrombosis and Haemostasis, 86 :923-928 [Details] | |
| (2000) | 'The artificial artery' Caplice NM. Curr. Interv. Cardiol Rpt; (2000) 'The artificial artery'. Current Interventional Cardiology Report, 2 :7-10 [Details] | |
| (2000) | 'Primary percutaneous coronary intervention in acute MI; evidence for decreasing mortality' Velianou J, Caplice N,Wilson S,Grill D, Reeder G, Bell M. ; (2000) 'Primary percutaneous coronary intervention in acute MI; evidence for decreasing mortality'. Mayo Clinic Proceedings, 75 :994-1001 [Details] | |
| (2000) | 'Activated nuclear factor-B is present in the coronary vasculature in experimental hypercholesteremia' Wilson SH, Caplice N, Simari R, Carlson P, Holmes D, Lerman A. ; (2000) 'Activated nuclear factor-B is present in the coronary vasculature in experimental hypercholesteremia'. Atherosclerosis, 148 :23-30 [Details] | |
| (1999) | 'Gene transfer for coronary restenosis' Caplice N, Simari R. ; (1999) 'Gene transfer for coronary restenosis'. Curr. Interv Card Rpt, 1 (2):157-164 [Details] | |
| (1999) | 'Regulation of caveolin expression and localization in smooth muscle cells' Peterson T, Kleppe L, Caplice N, Mueske C, Pan S, Simari R. ; (1999) 'Regulation of caveolin expression and localization in smooth muscle cells'. Biochemical Biophysical Research Communications, 265 :722-727 [Details] | |
| (1999) | 'The role of gene therapy for intimal hyperplasia of bypass grafts' Cable DG, Caccitolo JA, Caplice N, O'Brien T, Simari R, Dearani J, Mullany C, Orszulak T,Schaff H. ; (1999) 'The role of gene therapy for intimal hyperplasia of bypass grafts'. Circulation, 100 (SuppII):392-396 [Details] | |
| (1999) | 'Molecular biology and gene therapy in atherosclerosis in the stenting era' Caplice NM, Simari RD, ; (1999) 'Molecular biology and gene therapy in atherosclerosis in the stenting era'. International Journal of Cardiovascular Intervension, 2 (3):141-152 [Details] | |
| (1998) | 'The Role of Tissue Factor in Vascular Disease' Caplice NM, Simari RD. . ; (1998) 'The Role of Tissue Factor in Vascular Disease'. J Israel Heart Soc, 8 :18-20 [Details] | |
| (1998) | 'Modification of molecular events in coronary restenosis using coated stents. The Mayo Clinic Approach' Keelan PC, Miyauchi K, Caplice NM, Ashai KH, Schwartz RS.; (1998) 'Modification of molecular events in coronary restenosis using coated stents. The Mayo Clinic Approach'. Journal of Interventional Cardiology, 3 (3-4):211-215 [Details] | |
| (1998) | 'Expression of tissue factor pathway inhibitor in vascular smooth muscle cells and its regulation by growth factors' Caplice NM, Mueske CS, Kleppe LS, Peterson TE, Broze GJ, Simari RD. ; (1998) 'Expression of tissue factor pathway inhibitor in vascular smooth muscle cells and its regulation by growth factors'. Circulation Research, 83 :1264-1270 [Details] | |
| (1998) | 'New insights into the mechanisms of thrombogenesis in atherosclerosis' Caplice NM, Simari RD; (1998) 'New insights into the mechanisms of thrombogenesis in atherosclerosis'. Cardiologia, 43 (supplement 2) :725-730 [Details] | |
| (1998) | 'The presence of tissue factor pathway inhibitor in human atherosclerotic plaques is associated with reduced tissue factor activity' Caplice NM, Mueske CS, Kleppe LS, Simari RD. ; (1998) 'The presence of tissue factor pathway inhibitor in human atherosclerotic plaques is associated with reduced tissue factor activity'. Circulation, 98 :1051-1057 [Details] | |
| (1997) | 'Growth factors released into the coronary circulation after vascular injury promote proliferation of human vascular smooth muscle cells in culture' Caplice NM, CN Aroney, JHN Bett, J Cameron, J Campbell, N Hoffmann, P McEniery, MJ West; (1997) 'Growth factors released into the coronary circulation after vascular injury promote proliferation of human vascular smooth muscle cells in culture'. Journal of American College of Cardiology, 29 (7):1536-1541 [Details] | |
| (1995) | 'Rabbit models of atherosclerosis and restenosis' Caplice NM, PA Fennessy, JA Manderson, GR Campbell, JH Campbell ; (1995) 'Rabbit models of atherosclerosis and restenosis'. Atherosclerosis X, :114-120 [Details] | |
| (1994) | 'Inhibition of human vascular smooth muscle growth by heparin' Caplice NM, MJ West, GR Campbell, J Campbell ; (1994) 'Inhibition of human vascular smooth muscle growth by heparin'. The Lancet, 344 :97-98 [Details] | |
| (1994) | 'A ONE-YEAR MULTICENTER STUDY OF SIMVASTATIN IN THE TREATMENT OF HYPERCHOLESTEROLEMIA' GRAHAM, I,ROBINSON, K,TOMKIN, G,BRADFORD, NC,WILKINSON, P,BUCKLEY, B,SEED, M,MARENAH, CB,SILAS, J,CAPLICE, N,FENNELL, W,KALEEM,WENT, J,REPPER, J,VANNAN, M,TAYLOR, D,RICHARDSON, PJ,RITTOO,GRANT, A,COUNIHAN, TB,HERSH, AD,GUPTHA, S,GENTRY, R,YOUNG, J,GWILT, DJ,FOX, K,MULCAHY, D,GREENWOOD, RH,ROWLANDS, DB,CRAMB, R,ARNSTEN,MOURANT, AJ,ROBERTS,SANTRY,TAYLOR, WH,WALKER, BA,ALLEN, S,WOOD, DA,IVERSEN, SA,LAKER, MF,GAMA, RM,HUGHES, EA,POLANSKA, A,BENNETT, ED,FARRELL,WRAY, R,GINKS, S,CREAN, PA,HALL, M,HARTLEY, P,OCONNOR, P,WALSH, M,BAYNES, C,ELKELES, RS,BLOOMFIELD, P,WRIGHT, R,LINDSEY, J,CULLEN, P,MI, MA,FEELY, J,LOCKTON, A,COLLINSON,FINK, RS,WILSON, I,MILLER, JP,DAVIES, R,PATTERSON, DLH,BRUCE, R,CROOK, D,WYNN, V,OLIVER, M (1994) 'A ONE-YEAR MULTICENTER STUDY OF SIMVASTATIN IN THE TREATMENT OF HYPERCHOLESTEROLEMIA'. British Journal Of Clinical Practice, 48 :231-235 [Details] |
Other Journals
| Year | Publication | |
|---|---|---|
| (2011) | 'New therapeutic potential of microRNA treatment to target vulnerable atherosclerotic lesions and plaque rupture' Martin K, O'Sullivan JF, Caplice NM (2011) 'New therapeutic potential of microRNA treatment to target vulnerable atherosclerotic lesions and plaque rupture' Current Opinion in Cardiology, 26 (6) :569-575. [Details] |
Conference Publications
| Year | Publication | |
|---|---|---|
| (2013) | American Heart Association (AHA), BCVS, Las Vegas, USA, 2013 Turner EC, Huang CL, Sawhney N, Govindarajan K, Kumar AHS, Clover JP, Martin K, Leblond AL, Wang S, and Caplice NM (2013) Identification of a novel adult smooth muscle-like stem/progenitor cell that facilitates formation of tissue engineered vascular tissue for use as vascular grafts in vivo American Heart Association (AHA), BCVS, Las Vegas, USA, 2013 [Details] | |
| (2011) | American College of Cardiology, Winner Cardiovascular Pharmacology YIA John F. O'Sullivan, Anne-Laure Leblond, Pat Metharom, Arun HS Kumar, Geraldine Kelly, Eva Hristova, Brian Hynes, Rosemary O'Connor, and Noel M. Caplice (2011) POTENT CARDIOPROTECTIVE EFFECTS OF LOW DOSE INSULIN-LIKE GROWTH FACTOR-1 (LD-IGF-1) TREATMENT POST MYOCARDIAL INFARCTION ARE MEDIATED THROUGH PHOSPHORYLATION OF THE IGF-1 RECEPTOR, GSK-3BETA INHIBITION AND SURVIVAL KINASE UPREGULATION- American College of Cardiology, Winner Cardiovascular Pharmacology YIA [Details] | |
| (2011) | Atherosclerosis Thrombosis and Vascular Biology Conference, 28th--‐30th April 2011. Hilton, Chicago, Illinois,USA Pat Metharom, Kenneth Martin, Arun HS Kumar, Noel M Caplice. (2011) Pleiotropic Role for Monocyte C--‐fms Protein in Response to Vascular Injury:= Potential Therapeutic Target Atherosclerosis Thrombosis and Vascular Biology Conference, 28th--‐30th April 2011. Hilton, Chicago, Illinois,USA [Details] | |
| (2011) | American Heart Association - Finalist Melvin Judkins YIA John F O'Sullivan, Anne-Laure Leblond, John O'Dea, Ivalina Hristova, Sujith Kumar, Noel M Caplice, (2011) Multi Detector CT Accurately Defines Infarct Size, but not Microvascular Obstruction Post Myocardial Infarction, and Sodium Nitrite Increases Microvascular Obstruction Region Blood Flow Without Affecting CT Hypoenchancement Area American Heart Association - Finalist Melvin Judkins YIA [Details] | |
| (2011) | Atherosclerosis Thrombosis and Vascular Biology Conference, 28th--‐30th April 2011. Hilton, Chicago, Illinois,USA HS Kumar, Kenneth Martin, Noel M Caplice (2011) Deficiency Of CX3CR1 Receptors Results in Formation of Leaky Microvessels in Plaque Atherosclerosis Thrombosis and Vascular Biology Conference, 28th--‐30th April 2011. Hilton, Chicago, Illinois,USA [Details] | |
| (2011) | Irish Cardiac Society, Winner YIA John F O’Sullivan, M.D., Anne-Laure Leblond, PhD, Geraldine Kelly, BSc, Arun HS Kumar DVM, PhD, Pat Metharom, PhD, Chirlei K Büneker, PhD, Niki Alizadeh-Vikali, MSc, BHSc, Ivalina Hristova, BS, Brian G Hynes, M.D., Rosemary O’Connor, PhD, Noel M Caplice, (2011) Potent Long-term Cardioprotective Effects of Single Low Dose Insulin-like Growth Factor-1 (LD-IGF-1) Treatment Post Myocardial Infarction Irish Cardiac Society, Winner YIA [Details] | |
| (2008) | Arteriosclerosis, thrombosis and vascular biology annual conference AHA 2008 "Smooth Muscle Progenitors Cells and Vascular Disease-The Plot Thickens" ; (2008) Smooth Muscle Progenitors Cells and Vascular Disease-The Plot Thickens Arteriosclerosis, thrombosis and vascular biology annual conference AHA 2008 Atlanta Georgia, , 01-APR-08 - 30-APR-08 [Details] | |
| (2007) | Life Sciences 2007 Pierce W, Murphy SC, Metharom P, Sheehan D, Caplice NM, Mackrill JJ.; (2007) Calcium signalling in vascular stem cells Life Sciences 2007 Glasgow, [Details] | |
| (2007) | Life Sciences 2007 Pierce WG, Murphy SC, Sheehan D, Caplice NM, Mackrill JJ.; (2007) Atypical calcium responses evoked by fibrinogen in vascular stem cells Life Sciences 2007 Glasgow, [Details] | |
| (2007) | Royal Academy of Medicine in Ireland, Section of Biomedical Sciences, Summer Meeting Pierce W, Caplice NM, Metharom P, Mackrill JJ. ; (2007) Atypical Ca2+ responses to fibrinogen in endothelial progenitor cells Royal Academy of Medicine in Ireland, Section of Biomedical Sciences, Summer Meeting Ireland, [Details] |
Abstract
| Year | Publication | |
|---|---|---|
| (2012) | Potent long-term cardioprotective effects of single low dose insulin-like growth factor-1 (LD-IGF-1) treatment post myocardial infarction. O'sullivan, JF,Leblond, AL,Kelly, G,Kumar, AHS,Metharom, P,Buneker, CK,Alizadeh-Vikali, N,Hynes, BG,O'connor, R,Caplice, NM (2012) Potent long-term cardioprotective effects of single low dose insulin-like growth factor-1 (LD-IGF-1) treatment post myocardial infarction. Abstract [Details] | |
| (2011) | Monocyte recruitment via the CX3CR1 receptor influences burn wound healing. Clover, AJP,Kumar, AHS,Caplice, NM (2011) Monocyte recruitment via the CX3CR1 receptor influences burn wound healing. Abstract [Details] | |
| (2011) | Downregulation of the chemokine receptor CX3CR1 in active RA associated with a pro-osteoclastogenic phenotype. Murphy, G,Ryan, J,Harney, S,Shanahan, F,Molloy, M,Caplice, N (2011) Downregulation of the chemokine receptor CX3CR1 in active RA associated with a pro-osteoclastogenic phenotype. Abstract [Details] | |
| (2011) | Protection from collagen-induced arthritis in a CX3CR1 deficient mouse strain. Murphy, G,Kumar, A,Shanahan, F,Harney, S,Molloy, M,Caplice, N (2011) Protection from collagen-induced arthritis in a CX3CR1 deficient mouse strain. Abstract [Details] | |
| (2011) | POTENT CARDIOPROTECTIVE EFFECTS OF LOW DOSE INSULIN-LIKE GROWTH FACTOR-1 (LD-IGF-1) TREATMENT POST MYOCARDIAL INFARCTION ARE MEDIATED THROUGH PHOSPHORYLATION OF THE IGF-1 RECEPTOR, GSK-3BETA INHIBITION AND SURVIVAL KINASE UPREGULATION. O'Sullivan, JF,Leblond, AL,Metharom, P,Kumar, AHS,Kelly, G,Hristova, E,Hynes, B,O'Connor, R,Caplice, NM (2011) POTENT CARDIOPROTECTIVE EFFECTS OF LOW DOSE INSULIN-LIKE GROWTH FACTOR-1 (LD-IGF-1) TREATMENT POST MYOCARDIAL INFARCTION ARE MEDIATED THROUGH PHOSPHORYLATION OF THE IGF-1 RECEPTOR, GSK-3BETA INHIBITION AND SURVIVAL KINASE UPREGULATION. Abstract [Details] | |
| (2011) | PRO-OSTEOCLASTOGENIC PHENOTYPE OF MONOCYTE SUBSETS IN ACTIVE RA CHARACTERIZED BY DOWNREGULATION OF SURFACE CX3CR1. Murphy, G,Ryan, J,Harney, S,Shanahan, F,Caplice, N,Molloy, M (2011) PRO-OSTEOCLASTOGENIC PHENOTYPE OF MONOCYTE SUBSETS IN ACTIVE RA CHARACTERIZED BY DOWNREGULATION OF SURFACE CX3CR1. Abstract [Details] | |
| (2011) | CX3CR1 DEFICIENCY RESULTS IN PROTECTION FROM COLLAGEN-INDUCED ARTHRITIS IN A TRANSGENIC MOUSE MODEL. Murphy, G,Kumar, A,Shanahan, F,Harney, S,Molloy, M,Caplice, N (2011) CX3CR1 DEFICIENCY RESULTS IN PROTECTION FROM COLLAGEN-INDUCED ARTHRITIS IN A TRANSGENIC MOUSE MODEL. Abstract [Details] | |
| (2010) | TAKOTSUBO CARDIOMYOPATHY-A LARGE COHORT, MULTI CENTRE FOLLOW UP. Kasim, S,Moran, D,O'Donnabhain, R,Cronin, E,Kerins, D,Vaughan, C,Kelly, P,Curtin, R,Caplice, N (2010) TAKOTSUBO CARDIOMYOPATHY-A LARGE COHORT, MULTI CENTRE FOLLOW UP. Abstract [Details] | |
| (2007) | Molecular tracking of bone marrow progenitor differentiation in vitro. Schmeckpeper, J,Caplice, N,Ikeda, Y (2007) Molecular tracking of bone marrow progenitor differentiation in vitro. Abstract [Details] | |
| (2006) | Vascular progenitor cells lineage controversies. Caplice, N (2006) Vascular progenitor cells lineage controversies. Abstract [Details] |
Book Reviews
| Year | Publication | |
|---|---|---|
| (2011) | Microribonucleic Acids for Prevention of Plaque Rupture and In-Stent Restenosis A Finger in the Dam. O'Sullivan, JF,Martin, K,Caplice, NM (2011) Microribonucleic Acids for Prevention of Plaque Rupture and In-Stent Restenosis A Finger in the Dam. Book Reviews [DOI] [Details] |
Other
| Year | Publication | |
|---|---|---|
| (2007) | Arterial Blood Pressure Gradient Across Vulnerable Plaque Might Increase Rupture - Reply. Doyle, B, Caplice, N; (2007) Arterial Blood Pressure Gradient Across Vulnerable Plaque Might Increase Rupture - Reply. Other [DOI] [Details] |
Professional Activities
Honours and Awards
| Year | Title | Awarding Body | |
|---|---|---|---|
| 1994 | Prince Charles Research Award, University of Queensland | Prince Charles Research | |
| 1995 | Young Investigator Award-Ralph Reader Prize, Cardiac Society, Australia / NZ | Cardiac Society Australia | |
| 1996 | Raymond Shanahan Prize in Cardiology, UCC | UCC, Ireland | |
| 1998 | CR75 Award, Mayo Clinic | Mayo Foundation Rochester MN | |
| 2003 | Gil Heat Institute Physician Scientist Award, University of Kentucky | Lexington | |
| 2009 | Stokes Medal, Irish Cardiac Society | Irish Cardiac Society, Ireland | |
| 2002 | MERCK Award, Athrosclerosis Research, USA | MERCK | |
| 1992 | Merck Scholarship in Cardiology, Australian Heart Foundation | Australian Heart Foundation |
Professional Associations
| Association | Function | From / To | |
|---|---|---|---|
| NIH -NHLBI Study Taskfore on Stem Cell Trials, Washington, USA | Inaugural taskforce member | 01-JUN-05 / 31-JUL-05 | |
| Illinois Regenerative Medicine Institute Chicago IL | External advisor | 01-JUL-05 / 30-SEP-05 | |
| European Atherosclerosis Society | Member | / | |
| Royal Collage of Physicians of Ireland | Fellow | / | |
| Australasian College of Physicians | Fellow | / | |
| Australian Cardiac Society | Member | / |
Patents
| Patent Number | Title | Granted | |
|---|---|---|---|
| 09/843, 295 | Mesh Stent for local drug-gene delivery | 01-JAN-05 | |
| P10378USPC | Smooth muscle stem cells from peripheral blood | 01-JAN-08 | |
| 7,790,493 | Smooth Muscle progenitor Cells | 07-SEP-10 |
Conference Contributions
| Year | Publication | |
|---|---|---|
| (2010) | Irish Cardiac Society Meeting, Professor Noel Caplice; (2010) Irish Cardiac Society Meeting. [Conference Organising Committee Chairperson], Irish Cardiac Society Meeting, Sligo, Ireland , 08-OCT-10 - 08-OCT-10. [Details] | |
| (2010) | Discovery to Delivery, Professor Noel Caplice; (2010) Chair at the ¿Translational Medicine 2010:Discovery to DeliveryDiscovery to Delivery. [Conference Organising Committee Chairperson], Discovery to Delivery, Trinity College, Dublin, Ireland, , 07-OCT-10 - 07-OCT-10. [Details] | |
| (2010) | Experimental acquisitions of cell therapy in STEMI, Professor Noel Caplice; (2010) Experimental acquisitions of cell therapy in STEMI. [Invited Seminars/Guest Lectures], Experimental acquisitions of cell therapy in STEMI, 1st International ¿Lario¿ Meeting on Cardiovascular Regenerative Medicine: , 11-JUN-10 - 12-JUN-10. [Details] | |
| (2010) | Scientific Sessions, American Heart Association Meeting, Professor Noel Caplice; (2010) Scientific Sessions, American Heart Association Meeting. [Invited Seminars/Guest Lectures], Scientific Sessions, American Heart Association Meeting, Chicago, USA , 13-NOV-10 - 17-NOV-10. [Details] | |
| (2010) | Health Research Board / Irish Medical Devices Association, Professor Noel Caplice; (2010) Primitive vascular progenitor cells in atherosclerosis¿. [Conference Organising Committee Chairperson], Health Research Board / Irish Medical Devices Association, Dublin , 28-OCT-10 - 28-OCT-10. [Details] | |
| (2009) | Vascular progenitor cells in cardiovascular disease¿a new frontier, Professor Noel Caplice; (2009) Vascular progenitor cells in cardiovascular disease¿a new frontier. [Invited Seminars/Guest Lectures], Vascular progenitor cells in cardiovascular disease¿a new frontier, 60th Annual Scientific Meeting of the Irish Cardiac Society, Kerry, Ireland , 08-OCT-09 - 09-OCT-09. [Details] | |
| (2009) | The role of progenitor cells in cardiac repair, Professor Noel Caplice; (2009) The role of progenitor cells in cardiac repair. [Invited Seminars/Guest Lectures], The role of progenitor cells in cardiac repair, Prague, Czech Rep , 11-OCT-09 - 14-OCT-09. [Details] | |
| (2009) | Stem cells for ischemic disease and angiogenesis, N. Caplice; (2009) Stem cells for ischemic disease and angiogenesis. [Invited Seminars/Guest Lectures], Stem cells for ischemic disease and angiogenesis, British Microcirculation Society, Birmingham, UK , 30-MAR-09 - 31-MAR-09. [Details] | |
| (2008) | Translational Imaging - New Insights into Cardiovascular Disease, ; (2008) Translational Imaging - New Insights into Cardiovascular Disease. [Oral Presentation], Translational Imaging - New Insights into Cardiovascular Disease, Cork , 01-SEP-08 - 30-SEP-08. [Details] | |
| (2008) | Repair therapy for the myocardium after acute MI, Repair therapy for the myocardium after acute MI; (2008) Repair therapy for the myocardium after acute MI. [Oral Presentation], Repair therapy for the myocardium after acute MI, A.Menarini National CHF Symposium for Hospital Doctors , 01-APR-08 - 30-APR-08. [Details] | |
| (2008) | Hemodynamics for the cardiology Trainee, Hemodynamics for the cardiology Trainee ; (2008) Hemodynamics for the cardiology Trainee Organiser/ Director. [Conference Organising Committee Member], Hemodynamics for the cardiology Trainee, Cork , 01-JUL-08 - 31-JUL-08. [Details] | |
| (2008) | Frontiers in Cardiovascular Medicine, Frontiers in Cardiovascular Medicine ; (2008) Frontiers in Cardiovascular Medicine. [Conference Organising Committee Member], Frontiers in Cardiovascular Medicine, Cork , 01-DEC-08 - 20-DEC-08. [Details] | |
| (2008) | Cell therapy for acute myocardial infarction:where are we in 2008? , Cell therapy for acute myocardial infarction:where are we in 2008? ; (2008) Cell therapy for acute myocardial infarction:where are we in 2008? . [Oral Presentation], Cell therapy for acute myocardial infarction:where are we in 2008? , Torino , 01-NOV-08 - 30-NOV-08. [Details] | |
| (2008) | British Cardiovascular Forum, British Cardiovascular Forum.; (2008) British Cardiovascular Forum. [Invited Oral Presentation], British Cardiovascular Forum, Duoro Portugal , 01-JUN-08 - 30-JUN-08. [Details] | |
| (2008) | Arteriosclerosis, thrombosis and vascular biology annual conference AHA 2008, "Smooth Muscle Progenitors Cells and Vascular Disease-The Plot Thickens" ¿Invited talk Arteriosclerosis, thrombosis and vascular biology annual conference AHA 2008.; (2008) Arteriosclerosis, thrombosis and vascular biology annual conference AHA 2008. [Oral Presentation], Arteriosclerosis, thrombosis and vascular biology annual conference AHA 2008, Atlanta Georgia , 01-APR-08 - 30-APR-08. [Details] | |
| (2003) | First Mayo Clinic-Siebens Symposium on Stem Cell Therapy, First Mayo Clinic-Siebens Symposium on Stem Cell Therapy ; (2003) First Mayo Clinic-Siebens Symposium on Stem Cell Therapy Co-director. [Conference Organising Committee Member], First Mayo Clinic-Siebens Symposium on Stem Cell Therapy, Mayo Clinic, Rochester, MN , 01-JAN-03 - 31-DEC-03. [Details] |
Employment
| Employer | Position | From / To | |
|---|---|---|---|
| Centre for Reseach in Vascular Biology, UCC | Professor | 12-SEP-05 / | |
| Mayo Clinic | Instructor in Medicine | 01-JAN-97 / 31-DEC-05 | |
| Mayo Clinic | Consultant Cardiologist | 01-JAN-99 / 31-DEC-05 | |
| Mayo Clinic | Asst. Professor | 01-JAN-01 / 31-DEC-05 | |
| Cork University Hospital | Consultant Cardiologist | 30-SEP-05 / |
Education
| Year | Institution | Qualification | Subject | |
|---|---|---|---|---|
| 1997 | University of Queensland, Brisbane, Austrailia. | PHD | biology | |
| 1986 | University College Cork | MB CHB | Medicine |
Consultancy
| Client | Description | |
|---|---|---|
| SAB member Edward Lifesciences Irvine CA |
Teaching Activities
Teaching Interests
Undergraduate and graduate medical students-clinical cardiology
Doctorate and postdoctorate science graduates-vascular biology
Core interests are in the areas of interventional cardiology as it relates to cardiac repair, vascular biology, vascular disease, translational medicine and novel therapeutics