Noel Caplice

Professor
Medicine Department
University College Cork
Cork
Ireland

T: +353-21-490-3000
E: N.Caplice@ucc.ie
Professor
Medical School
2.40
Crvb, Biosciences Institute,
University College Cork
Cork
Ireland

T: +353-21-490-1329
F: +353-21-490-1442
E: N.Caplice@ucc.ie

Professor Noel Caplice is Professor of Cardiovascular Sciences in the Department of Medicine and Director of the Centre for Research in Vascular Biology at University College Cork.

 

He is also a Consultant Cardiologist at Cork University Hospital.

 

He previously held professional positions in pharmacology and medicine at the Mayo Clinic, Rochester, Minnesota, USA, where he was an interventional cardiologist and directed the Vascular Stem Cell Laboratory.


 

Professor Caplice¿s Centre for Research in Vascular Biology research programme is addressing fundamental questions in vascular stem cell biology, atherosclerosis and vascular remodelling with emphasis on translation of ideas to the clinical cardiology arena in areas of novel diagnostics and therapeutics in the field of stem cells, gene delivery and tissue engineering.

Research Interests

1. Detection of human smooth muscle progenitor cells in blood and

 

human atherosclerotic plaque.

 




 2.

Determinatiing the cardiac repair potential of specific cytoprotective factors in models of myocardilal infarction





3. 

Realtime tracking of stem cells in vivo and evaluation of paracrine cardiomyocyte repair effects of progenitor cells




 4. Biology of vacsular progenitor cells and smooth muscle progenitor cells in animal models of atheroaclerosis, graft engineering, remodeling after stent injury and myocardial infarction

Book Chapters

YearPublication
(2011)'Key Role of Angiogenic Control in Recovery from Ischaemic Heart Disease’'
John F O’Sullivan, Anne-Laure Leblond, Noel M Caplice. M Slevin (2011) 'Key Role of Angiogenic Control in Recovery from Ischaemic Heart Disease’' In: Therapeutic Angiogenesis for Vascular Diseases. DOI 10.1007/978-90-481-9495-7_12: Springer Science-Business Media B.V. [Details]
(2010)'Gene transfer for coronary restenosis'
Caplice, NM; Simari, RD; (2010) 'Gene transfer for coronary restenosis' In: Current Review of Interventional Cardiology.4th Ed. Philadelphia: Current Medicine Inc. [Details]
(2010)'New biologic developments in stents and grafts'
Caplice., NM; (2010) 'New biologic developments in stents and grafts' In: Textbook of Interventional Cardiology. Armonk, NY: Futura Publishing. [Details]
(2010)'A key role for angiogenesis in recovery from myocardial infarction'
O'Sullivan, JF; Leblond, AL; Caplice, NM; (2010) 'A key role for angiogenesis in recovery from myocardial infarction' In: MA Slevin (eds). Therapeutic Angiogenesis for Vascular Diseases. New York: Springer-Verlag. [Details]
(2006)'Safety Concerns in the Cell Therapy Era'
Deb A, Caplice NM. ; (2006) 'Safety Concerns in the Cell Therapy Era' In: Textbook of Cellular Therapies in Cardiovascular Diseases. USA: Eds: Willerson & Perin. [Details]
(1999)'Adenoviral vectors for cardiovascular diseases'
Caplice NM, O'Brien T, Simari RD; (1999) 'Adenoviral vectors for cardiovascular diseases' In: Prem Seth (eds). Adenoviruses:Basic biology to gene therapy. Austin, TX: RG Landes. [Details]
(1995)'Rabbit models of atherosclerosis and restenosis'
Caplice NM, Fennessy PA, Manderson JA, Campbell GR, Campbell JH; (1995) 'Rabbit models of atherosclerosis and restenosis' In: FP Woodford (eds). Atherosclerosis. Amsterdam: Elsevier. [Details]

Peer Reviewed Journals

YearPublication
(2013)'Regenerative Approaches to Post-Myocardial Infarction Heart Failure'
Martin K, Huang CL, Caplice NM (2013) 'Regenerative Approaches to Post-Myocardial Infarction Heart Failure' [Details]
(2013)'Differential Endothelial Coverage, Response to Injury and Neointimal Integration of CX3CR1/Smooth Muscle-Like Cells after Carotid or Femoral Arterial Injury'
Martin K, Kumar AH, Klinkert K, Caplice NM (2013) 'Differential Endothelial Coverage, Response to Injury and Neointimal Integration of CX3CR1/Smooth Muscle-Like Cells after Carotid or Femoral Arterial Injury' [DOI] [Details]
(2013)'Role of CX3CR1 receptor in monocyte/macrophage driven neovascularization'
Kumar AH, Martin K, Turner EC, Buneker CK, Dorgham K, Deterre P, Caplice NM (2013) 'Role of CX3CR1 receptor in monocyte/macrophage driven neovascularization' [DOI] [Details]
(2013)'Pregnancy-specific glycoproteins bind integrin αIIbβ3 and inhibit the platelet-fibrinogen interaction'
Shanley DK, Kiely PA, Golla K, Allen S, Martin K, O'Riordan RT, Ball M, Aplin JD, Singer BB, Caplice N, Moran N, Moore T (2013) 'Pregnancy-specific glycoproteins bind integrin αIIbβ3 and inhibit the platelet-fibrinogen interaction' [DOI] [Details]
(2013)'Multidetector computed tomography accurately defines infarct size, but not microvascular obstruction after myocardial infarction'
O'Sullivan JF, Leblond AL, O'Dea J, Hristova I, Kumar S, Martin K, Kumar AH, Caplice NM (2013) 'Multidetector computed tomography accurately defines infarct size, but not microvascular obstruction after myocardial infarction' [DOI] [Details]
(2011)'Potent endothelial progenitor cell-conditioned media-related anti-apoptotic, cardiotrophic, and pro-angiogenic effects post-myocardial infarction are mediated by insulin-like growth factor-1'
Hynes B, Kumar AH, O'Sullivan J, Klein Buneker C, Leblond AL, Weiss S, Schmeckpeper J, Martin K, Caplice NM (2011) 'Potent endothelial progenitor cell-conditioned media-related anti-apoptotic, cardiotrophic, and pro-angiogenic effects post-myocardial infarction are mediated by insulin-like growth factor-1' [DOI] [Details]
(2011)'Calcium signalling in adult endothelial outgrowth cells'
Pierce WG, Zanette C, Caplice NM, Mackrill JJ (2011) 'Calcium signalling in adult endothelial outgrowth cells' [DOI] [Details]
(2011)'Improved protocol for processing stented porcine coronary arteries for immunostaining'
Kumar AH, McCauley SD, Hynes BG, O'Dea J, Caplice NM; (2011) 'Improved protocol for processing stented porcine coronary arteries for immunostaining' Globe icon [Details]
(2011)'Role of vessel wall and bone marrow syndecan-4 in newintimal hyperplasia: the plot thickens'
Caplice NM (2011) 'Role of vessel wall and bone marrow syndecan-4 in newintimal hyperplasia: the plot thickens' [Details]
(2011)'Microribonucleic acids for prevention of plaque rupture and in-stent restenosis: a finger in the dam'
O'Sullivan JF, Martin K, Caplice NM (2011) 'Microribonucleic acids for prevention of plaque rupture and in-stent restenosis: a finger in the dam' [DOI] [Details]
(2011)'New therapeutic potential of microRNA treatment to target vulnerable atherosclerotic lesions and plaque rupture'
Martin K, O'Sullivan JF, Caplice NM (2011) 'New therapeutic potential of microRNA treatment to target vulnerable atherosclerotic lesions and plaque rupture' [DOI] [Details]
(2011)'Pleiotropic role for monocyte C-fms protein in response to vascular injury: potential therapeutic target'
Metharom P, Martin K, Kumar AH, Sawhney N, Cronin MF, McCarthy DG, Maguire AR, Caplice NM (2011) 'Pleiotropic role for monocyte C-fms protein in response to vascular injury: potential therapeutic target' [DOI] [Details]
(2011)'Pleiotropic role for monocyte C-fms protein in response to vascular injury: Potential therapeutic target'
Metharom P, Martin K, Kumar AH, Sawhney N, Cronin MF, McCarthy DG, Maguire AR, Caplice NM; (2011) 'Pleiotropic role for monocyte C-fms protein in response to vascular injury: Potential therapeutic target' Globe icon [Details]
(2011)'Deficiency of CX3CR1 delays burn wound healing and is associated with reduced myeloid cell recruitment and decreased sub-dermal angiogenesis'
Clover AJ, Kumar AH, Caplice NM; (2011) 'Deficiency of CX3CR1 delays burn wound healing and is associated with reduced myeloid cell recruitment and decreased sub-dermal angiogenesis' Globe icon [Details]
(2011)'Improved protocol for processing stented porcine coronary arteries for immunostaining'
Kumar, AHS,McCauley, SD,Hynes, BG,O'Dea, J,Caplice, NM; (2011) 'Improved protocol for processing stented porcine coronary arteries for immunostaining' [DOI] [Details]
(2011)'Potent long-term cardioprotective effects of single low-dose insulin-like growth factor-1 treatment postmyocardial infarction'
O'Sullivan JF, Leblond AL, Kelly G, Kumar AH, Metharom P, Büneker CK, Alizadeh-Vikali N, Hristova I, Hynes BG, O'Connor R, Caplice NM; (2011) 'Potent long-term cardioprotective effects of single low-dose insulin-like growth factor-1 treatment postmyocardial infarction' Globe icon [Details]
(2010)'Clinical Potential of Adult Vascular Progenitor Cells'
Kumar, AHS; Caplice, NM; (2010) 'Clinical Potential of Adult Vascular Progenitor Cells' [DOI] [Details]
(2010)'A Specific Subset of Mouse Bone Marrow Cells Has Smooth Muscle Cell Differentiation Capacity-Brief Report'
Metharom, P; Kumar, AHS; Weiss, S; Caplice, NM; (2010) 'A Specific Subset of Mouse Bone Marrow Cells Has Smooth Muscle Cell Differentiation Capacity-Brief Report' [DOI] [Details]
(2010)'Bone marrow-derived CX(3)CR1 progenitors contribute to neointimal smooth muscle cells via fractalkine CX(3)CR1 interaction'
Kumar, AHS; Metharom, P; Schmeckpeper, J; Weiss, S; Martin, K; Caplice, NM; (2010) 'Bone marrow-derived CX(3)CR1 progenitors contribute to neointimal smooth muscle cells via fractalkine CX(3)CR1 interaction' [DOI] [Details]
(2010)'Contrast enhanced ultrasound and the enigma of plaque neovascularisation'
Caplice, NM; Martin K; (2010) 'Contrast enhanced ultrasound and the enigma of plaque neovascularisation' [Details]
(2010)'Bone marrow-derived CX3CR1 progenitors contribute to neointimal smooth muscle cells via fractalkine CX3CR1 interaction'
Kumar AH, Metharom P, Schmeckpeper J, Weiss S, Martin K, Caplice NM (2010) 'Bone marrow-derived CX3CR1 progenitors contribute to neointimal smooth muscle cells via fractalkine CX3CR1 interaction' [DOI] [Details]
(2009)'Myeloid Lineage of Human Endothelial Outgrowth Cells Circulating in Blood and Vasculogenic Endothelial-Like Cells in the Diseased Vessel Wall'
Liu, CS,Wang, SH,Metharom, P,Caplice, NM; (2009) 'Myeloid Lineage of Human Endothelial Outgrowth Cells Circulating in Blood and Vasculogenic Endothelial-Like Cells in the Diseased Vessel Wall' [DOI] [Details]
(2009)'Bone marrow mononuclear stem cells in treatment of myocardial infarction'
Leblond AL, O'Sullivan J, Caplice N.; (2009) 'Bone marrow mononuclear stem cells in treatment of myocardial infarction' [Details]
(2009)'Myeloid lineage of human endothelial outgrowth cells circulating in blood and vasculogenic endothelial-like cells in the diseased vessel wall'
Liu C, Wang S, Metharom P, Caplice NM; (2009) 'Myeloid lineage of human endothelial outgrowth cells circulating in blood and vasculogenic endothelial-like cells in the diseased vessel wall' [Details]
(2009)'Thrombin stimulates smooth muscle cell differentiation from peripheral blood mononuclear cells via protease-activated receptor-1, RhoA, and myocardin'
Martin K, Weiss S, Metharom P, Schmeckpeper J, Hynes B, O'Sullivan J, Caplice N (2009) 'Thrombin stimulates smooth muscle cell differentiation from peripheral blood mononuclear cells via protease-activated receptor-1, RhoA, and myocardin' [DOI] [Details]
(2009)'Lentiviral tracking of vascular differentiation in bone marrow progenitor cells'
Schmeckpeper, J,Ikeda, Y,Kumar, AHS,Metharom, P,Russell, SJ,Caplice, NM; (2009) 'Lentiviral tracking of vascular differentiation in bone marrow progenitor cells' [DOI] [Details]
(2008)'Myeoloid lineage of high proliferative potential human smooth muscle outgrowth cells circulating in blood and vasculogenic smooth muscle-like cells in vivo'
Metharom P, Liu C, Wang S. Stalboerger P, Chen G, Doyle B, Ikeda Y, Caplice NM ; (2008) 'Myeoloid lineage of high proliferative potential human smooth muscle outgrowth cells circulating in blood and vasculogenic smooth muscle-like cells in vivo' [Details]
(2008)'Progression of non-culprit stenosis following successful percutaneous intervention'
Bunch TJ, Rihal CS, Gumina RJ, Cooper L, Caplice NM. ; (2008) 'Progression of non-culprit stenosis following successful percutaneous intervention' [Details]
(2008)'Fractalkine in rheumatoid arthritis: a review to date'
Murphy G, Caplice N, Molloy M.; (2008) 'Fractalkine in rheumatoid arthritis: a review to date' [Details]
(2008)'Progenitor Cell Therapy in a Porcine Acute Myocardial Infarction Model Induces Cardiac Hypertrophy, Mediated by Paracrine Secretion of Cardiotrophic Factors Including TGF beta 1'
Doyle, B,Sorajja, P,Hynes, B,Kumar, AHS,Araoz, PA,Stalboerger, PG,Miller, D,Reed, C,Schmeckpeper, J,Wang, S,Liu, CS,Terzic, A,Kruger, D,Riederer, S,Caplice, NM; (2008) 'Progenitor Cell Therapy in a Porcine Acute Myocardial Infarction Model Induces Cardiac Hypertrophy, Mediated by Paracrine Secretion of Cardiotrophic Factors Including TGF beta 1' [DOI] [Details]
(2008)'Progenitor cell therapy for acute myocardial infraction induces cardiac hypertrophy, mediated by paracrine seceretion of cardiotrophic factors including TGF β1'
Doyle B, Sorajja P, Hynes B, Kumar A, Araoz PA, Stalboerger PS, Miller DV, Reed C,Schmeckpeper, Wang S, Liu C, Terzic A, Kruger D, Reiderer S, Caplice NM.; (2008) 'Progenitor cell therapy for acute myocardial infraction induces cardiac hypertrophy, mediated by paracrine seceretion of cardiotrophic factors including TGF β1' [Details]
(2007)'Infected cell carriers: a new strategy for systemic delievery of oncolytic measles viruses in cancer virotherapy'
Iankov ID, Blechacz B, Liu C, Schmeckpeper JD, Tarara JE, Federspiel MJ, Caplice N, Russell SJ. ; (2007) 'Infected cell carriers: a new strategy for systemic delievery of oncolytic measles viruses in cancer virotherapy' [Details]
(2007)'Clinical trails in stem cell therapy: pitfalls and lessons for the future'
Metharom P, Doyle B, Caplice NM. ; (2007) 'Clinical trails in stem cell therapy: pitfalls and lessons for the future' [Details]
(2007)'Vascular disease: a new progenitor biology'
Metharom P, Capice NM. ; (2007) 'Vascular disease: a new progenitor biology' [Details]
(2007)'Plaque Neovascularization and Antiangiogenic Therapy For Atherosclerosis'
Doyle, B, Caplice, N; (2007) 'Plaque Neovascularization and Antiangiogenic Therapy For Atherosclerosis' [Details]
(2007)'Dynamic tracking during intracoronary injection of F-18-FDG-labeled progenitor cell therapy for acute myocardial infarction'
Doyle, B,Kemp, BJ,Chareonthaitawee, P,Reed, C,Schmeckpeper, J,Sorajja, P,Russell, S,Araoz, P,Riederer, SJ,Caplice, NM; (2007) 'Dynamic tracking during intracoronary injection of F-18-FDG-labeled progenitor cell therapy for acute myocardial infarction' [DOI] [Details]
(2007)'Plaque neovascularization and antiangiogenic therapy for atherosclerosis'
Doyle B, Caplice N. ; (2007) 'Plaque neovascularization and antiangiogenic therapy for atherosclerosis' [Details]
(2007)'Dynamic Tracking During Intracoronary Injection of F-18-Fdg-Labeled Progenitor Cell Therapy For Acute Myocardial Infarction'
Doyle, B, Kemp, BJ, Chareonthaitawee, P, Reed, C, Schmeckpeper, J, Sorajja, P, Russell, S, Araoz, P, Riederer, SJ, Caplice, NM; (2007) 'Dynamic Tracking During Intracoronary Injection of F-18-Fdg-Labeled Progenitor Cell Therapy For Acute Myocardial Infarction' [DOI] [Details]
(2007)'Neoangiogenesis and the presence of progenitor cells in the venous limb of an arteriovenous fistula in the rat'
Caplice NM, Wang S, Tracz M, Croatt AJ, Grande JP, Katusic ZS, Nath KA. ; (2007) 'Neoangiogenesis and the presence of progenitor cells in the venous limb of an arteriovenous fistula in the rat' [Details]
(2006)'Future cell therapy for myocardial infarction'
Caplice NM. ; (2006) 'Future cell therapy for myocardial infarction' [Details]
(2006)'Endothelial progenitor cells'
Doyle, B,Metharom, P,Caplice, NM; (2006) 'Endothelial progenitor cells' [DOI] [Details]
(2006)'PAF receptor is preferentially expressed in a distinct synthetic phenotype of smooth muscle cells cloned from human internal thoracic artery. Functional implications in cell migration'
Stengel D, O¿Neil C, Brocheriou I, Karabina SA, Caplice NM, Pickering JG, Ninio E. ; (2006) 'PAF receptor is preferentially expressed in a distinct synthetic phenotype of smooth muscle cells cloned from human internal thoracic artery. Functional implications in cell migration' [Details]
(2006)'Functional and structural remodeling of myocardial microvasculature in early experimental hypertension'
Rodriguez-Porcel M, Zhu X, Chade A, Amores-Arriaga B, Caplice N, Ritman E, Lerman A, Lerman L. ; (2006) 'Functional and structural remodeling of myocardial microvasculature in early experimental hypertension' [Details]
(2006)'The impact of TGF-beta 1 on AV node conduction modification by injected autologous fibroblasts in the canine heart'
Bunch TJ, Mahaptra S, Bruce GK, Johnson SB, Miller DV, Wang XL, Lee HC, Caplice N, Packer DL.; (2006) 'The impact of TGF-beta 1 on AV node conduction modification by injected autologous fibroblasts in the canine heart' [Details]
(2006)'Targeting angiogenesis versus myogenesis with cardiac cell therapy'
Doyle B, Caplice NM. ; (2006) 'Targeting angiogenesis versus myogenesis with cardiac cell therapy' [Details]
(2006)'Endothelial Progenitor Cells'
Doyle, B, Metharom, P, Caplice, NM; (2006) 'Endothelial Progenitor Cells' [DOI] [Details]
(2006)'Nephrogenic fibrosing dermopathy and high dose erythropoietin therapy'
Swaminathan S, Ahmed I, McCarthy JT, Albright RC, Pittlekow MR, Caplice NM, Griffin MD, Leung N. ; (2006) 'Nephrogenic fibrosing dermopathy and high dose erythropoietin therapy' [Details]
(2006)'Functional and structural remodeling of myocardial microvasculature in early experimental hypertension'
Rodriguez-Porcel M, Zhu X, Chade A, Amores-Arriaga B, Caplice N, Ritman E, Lerman A, Lerman L. ; (2006) 'Functional and structural remodeling of myocardial microvasculature in early experimental hypertension' [Details]
(2005)'Vascular progenitor cells: origin and mechanisms of mobilization, differentiation, integration and vasculogenesis'
Doyle B, Caplice NM. ; (2005) 'Vascular progenitor cells: origin and mechanisms of mobilization, differentiation, integration and vasculogenesis' [Details]
(2005)'Bone marrow derived smooth muscle precursors in human heart valves'
Deb A, Wang S, Caplice NM. ; (2005) 'Bone marrow derived smooth muscle precursors in human heart valves' [Details]
(2005)'TFPI antigen and activity levels in patients with asymptomatic atherosclerosis and target organ acute and chronic complications'
Novo G, Caplice N, Tantillo, Bonura F, Simari R, Novo S. ; (2005) 'TFPI antigen and activity levels in patients with asymptomatic atherosclerosis and target organ acute and chronic complications' [Details]
(2005)'Cell therapy for cardiovascular diseases. What cell, when and to whom?'
Caplice NM, Alegria J,. ; (2005) 'Cell therapy for cardiovascular diseases. What cell, when and to whom?' [Details]
(2005)'Transgenic sickle mice are markedly sensitive to renal ischemia-reperfusion injury'
Nath KA, Croatt T, Grande JP, Hebbel RP, Caplice NM, Katusic ZS. ; (2005) 'Transgenic sickle mice are markedly sensitive to renal ischemia-reperfusion injury' [Details]
(2005)'A new source of endothelial progenitor cells ¿ vascular biology redefined'
Doyle B, Caplice NM.; (2005) 'A new source of endothelial progenitor cells ¿ vascular biology redefined' [Details]
(2005)'TFPI antigen and activity levels in patients with asymptomatic atherosclerosis and target organ acute and chronic complications. Int Angiol'
Novo G, Caplice N, Tantillo R, Bonura F, Simari R, Novo S.; (2005) 'TFPI antigen and activity levels in patients with asymptomatic atherosclerosis and target organ acute and chronic complications. Int Angiol' [Details]
(2005)'Cyclosporine decreases vascular progenitor cell number following cardiac transplantation and attenuates progenitor cell function'
Davies WR, Wang S, Oi K, Caplice NM, McGregor CGA. ; (2005) 'Cyclosporine decreases vascular progenitor cell number following cardiac transplantation and attenuates progenitor cell function' [Details]
(2005)'Letter regarding article by Rotmans et al, In vivo cell seeding with anti-CD34 antibodies successfully accelerates endothelialization but stimulates intimal hyperplasia in porcine arteriovenous expanded polytetrafluoroethylene grafts'
Doyle B, Caplice N. .; (2005) 'Letter regarding article by Rotmans et al, In vivo cell seeding with anti-CD34 antibodies successfully accelerates endothelialization but stimulates intimal hyperplasia in porcine arteriovenous expanded polytetrafluoroethylene grafts' [Details]
(2005)'Graft endothelialization and intimal hyperplasia'
Doyle B, Caplice NM. ; (2005) 'Graft endothelialization and intimal hyperplasia' [Details]
(2005)'Leptin receptor and functional effects of leptin in human endothelial progenitor cells'
Wolk R, Deb A, Caplice NM, Somers VK. ; (2005) 'Leptin receptor and functional effects of leptin in human endothelial progenitor cells' [Details]
(2005)'MCP-1 is upregulated in unstressed and stressed HO-1 knockout mice: pathophysiologic correlates'
Pittock ST, Norby SM, Grande JP, Croatt AJ, Bren GD, Badley AD, Caplice NM, Griffin MD, Nath KA. ; (2005) 'MCP-1 is upregulated in unstressed and stressed HO-1 knockout mice: pathophysiologic correlates' [Details]
(2005)'Unresolved questions, changing definitions and novel paradigms for defining endothelial progenitor cells'
Ingram DA, Caplice NM, Yoder MC. ; (2005) 'Unresolved questions, changing definitions and novel paradigms for defining endothelial progenitor cells' [Details]
(2005)'Pro-apoptotic, antimigratory, antiproliferative ande anti-angiogenic effects of commercial CRP on various human endothelial cell types in vitro: implications of contaminating presence of sodium azide in commercial preparation'
Liu C, Wang S, Deb A, Nath K, Katusic Z, McConnell J, Caplice NM. ; (2005) 'Pro-apoptotic, antimigratory, antiproliferative ande anti-angiogenic effects of commercial CRP on various human endothelial cell types in vitro: implications of contaminating presence of sodium azide in commercial preparation' [Details]
(2004)'Dog peritoneal and pleural cavities as bioreactors to grow autologous vascular grafts'
Chue WL, Campbell GR, Caplice N, Muhammed A, Berry C, Thomas AC, Bennett MB, Campbell JH. ; (2004) 'Dog peritoneal and pleural cavities as bioreactors to grow autologous vascular grafts' [Details]
(2004)'Antioxidant intervention attenuates myocardial neovascularization in hypercholesterolemia'
Zhu XY, Rodriguez-Porcel M, Bentley MD, Chade AR, Sica V, Napoli C, Caplice N, Ritman EL, Lerman A, Lerman LO. ; (2004) 'Antioxidant intervention attenuates myocardial neovascularization in hypercholesterolemia' [Details]
(2004)'Lipoprotein (a). New insights into mechanisms of atherogenesis and atherothrombosis'
Deb A, Caplice NM. ; (2004) 'Lipoprotein (a). New insights into mechanisms of atherogenesis and atherothrombosis' [Details]
(2004)'Fatal coronary artery disease after unrelated donor bone marrow transplantation'
Ghobrial IM, Bunch TJ, Caplice NM, Edwards WD, Miller DV, Litzow MR. ; (2004) 'Fatal coronary artery disease after unrelated donor bone marrow transplantation' [Details]
(2004)'Transplantation of circulating endothelial progenitor cells restores endothelial function of denuded rabbit carotid arteries'
He T, Smith LA, Richardson DM, Harrington S, Nath KA, Caplice NM, Katusic ZS. ; (2004) 'Transplantation of circulating endothelial progenitor cells restores endothelial function of denuded rabbit carotid arteries' [Details]
(2004)'Myocardial Cell replacement. The science, the clinic and the future'
Caplice NM. Deb A. ; (2004) 'Myocardial Cell replacement. The science, the clinic and the future' [Details]
(2004)'Smooth muscle progenitor cells in vascular disease'
Liu C, Nath KA, Katusic ZS.,Caplice NM ; (2004) 'Smooth muscle progenitor cells in vascular disease' [Details]
(2004)'Integrin profile and in vivo homing of human smooth muscle progenitor cells'
Deb A, Skelding KA, Wang S, Reeder M, Simper D, Caplice NM. ; (2004) 'Integrin profile and in vivo homing of human smooth muscle progenitor cells' [Details]
(2004)'Elevated expression of manganese superoxide dismutase is a critical protective mechanism against oxidative stress in human endothelial progenitor cells'
He T, Peterson T, Holmuhamedov E, Terzic A, Caplice NM, Oberley LW, Katusic ZS. ; (2004) 'Elevated expression of manganese superoxide dismutase is a critical protective mechanism against oxidative stress in human endothelial progenitor cells' [Details]
(2003)'Infectious and ischemic complications from percutaneous closure devices used after vascular access'
Boston US, Panneton JM, Hofer JM, Sabater EA, Caplice N, Rowland CM, Noel AA, Bower TC, Cherry Jr KJ, Gloviczki P. ; (2003) 'Infectious and ischemic complications from percutaneous closure devices used after vascular access' [Details]
(2003)'Smooth muscle cells in human coronary atherosclerosis can originate from cells administered at marrow transplantation'
Caplice NM Bunch TJ, Stalboerger P,Wang S, Simper D, Miller DV, Russell SJ, Litzow MR, Edwards WD. ; (2003) 'Smooth muscle cells in human coronary atherosclerosis can originate from cells administered at marrow transplantation' USA [Details]
(2003)'Bone marrow derived cardiomyocytes are present in adult human heart: A study of gender-mismatched bone marrow transplantation patients'
Deb A, Wang S, Skelding K, Miller D, Simper D, Caplice NM.; (2003) 'Bone marrow derived cardiomyocytes are present in adult human heart: A study of gender-mismatched bone marrow transplantation patients' [Details]
(2003)'Stem cells to repair the heart-A clinical perspective'
Caplice NM, Gersh BJ. ; (2003) 'Stem cells to repair the heart-A clinical perspective' [Details]
(2003)'Nitric Oxide synthase gene transfer as a tool to study biology of endothelial cells'
Katusic Z, Caplice NM, Nath KA. ; (2003) 'Nitric Oxide synthase gene transfer as a tool to study biology of endothelial cells' [Details]
(2003)'TFPI deficiency enhances neointimal proliferation and formation in a murine model of vascular remodeling'
Singh R, Pan S, Mueske C, Witt T, Kleppe L, Peterson T, Caplice NM, Simari RD. ; (2003) 'TFPI deficiency enhances neointimal proliferation and formation in a murine model of vascular remodeling' [Details]
(2003)'Quantifying Chimeric Cardiomyocytes-'
Deb A, Wang S, Skelding K, Simper D, Caplice NM. ; (2003) 'Quantifying Chimeric Cardiomyocytes-' [Details]
(2003)'Endothelial progenitor cells are decreased in blood of cardiac allograft subjects with vasculopathy and endothelial cells of non-cardiac origin are enriched in transplant atherosclerosis'
Simper D, Wang S, Deb A, Holmes DR, McGregor C, Frantz R, Kushwaha S, Caplice NM. ; (2003) 'Endothelial progenitor cells are decreased in blood of cardiac allograft subjects with vasculopathy and endothelial cells of non-cardiac origin are enriched in transplant atherosclerosis' [Details]
(2002)'A tissue-engineered stent for cell based vascular gene transfer'
Panetta C, Miyauchi K, Berry D, Simari RD, Holmes D, Schwartz R, Caplice NM. ; (2002) 'A tissue-engineered stent for cell based vascular gene transfer' [Details]
(2002)'Smooth muscle progenitor cells in human blood'
Simper D, Stalboerger P, Panetta C, Wang S, Caplice NM. ; (2002) 'Smooth muscle progenitor cells in human blood' [Details]
(2001)'Biologic alternatives to stents and grafts'
Caplice NM. ; (2001) 'Biologic alternatives to stents and grafts' [Details]
(2001)'Lipoprotein (a) binds and inactivates tissue factor pathway inhibitor: A novel link between lipoproteins and thrombosis'
Caplice NM, Peterson TF, Kleppe LS, Mueske CS, Kostner GM, Broze GJ, Simari RD. ; (2001) 'Lipoprotein (a) binds and inactivates tissue factor pathway inhibitor: A novel link between lipoproteins and thrombosis' [Details]
(2001)'Role for tissue factor pathway in murine model of vascular remodeling'
Singh R, Pan S, Mueske C, Witt T, Kleppe L, Peterson T, Slobodova A, Chang J, Caplice NM, Simari RD. ; (2001) 'Role for tissue factor pathway in murine model of vascular remodeling' [Details]
(2001)'Cell proliferation in carcinoid valve disease: a mechanism for serotonin effects'
Rajamannan N, Caplice N, Anthikad F, Sebo T, Orszulak TA, Edwards WD, Tajik AJ, Schwartz RS. ; (2001) 'Cell proliferation in carcinoid valve disease: a mechanism for serotonin effects' [Details]
(2001)'Remnant lipoproteins induce endothelial plasminogen activator inhibitor-1'
Sawka A, Singh RJ, Hiddinga HJ, McConnell JP, Eberhardt NL, Caplice NM, O¿Brien T. ; (2001) 'Remnant lipoproteins induce endothelial plasminogen activator inhibitor-1' [Details]
(2001)'Plasmin proteolysis of endothelial cell and vessel wall associated tissue factor pathway inhibitor'
Stalboerger P, Panetta C, Simari RD, Caplice NM. ; (2001) 'Plasmin proteolysis of endothelial cell and vessel wall associated tissue factor pathway inhibitor' [Details]
(2000)'Activated nuclear factor-B is present in the coronary vasculature in experimental hypercholesteremia'
Wilson SH, Caplice N, Simari R, Carlson P, Holmes D, Lerman A. ; (2000) 'Activated nuclear factor-B is present in the coronary vasculature in experimental hypercholesteremia' [Details]
(2000)'The artificial artery'
Caplice NM. Curr. Interv. Cardiol Rpt; (2000) 'The artificial artery' [Details]
(2000)'Primary percutaneous coronary intervention in acute MI; evidence for decreasing mortality'
Velianou J, Caplice N,Wilson S,Grill D, Reeder G, Bell M. ; (2000) 'Primary percutaneous coronary intervention in acute MI; evidence for decreasing mortality' [Details]
(1999)'Molecular biology and gene therapy in atherosclerosis in the stenting era'
Caplice NM, Simari RD, ; (1999) 'Molecular biology and gene therapy in atherosclerosis in the stenting era' [Details]
(1999)'Gene transfer for coronary restenosis'
Caplice N, Simari R. ; (1999) 'Gene transfer for coronary restenosis' [Details]
(1999)'The role of gene therapy for intimal hyperplasia of bypass grafts'
Cable DG, Caccitolo JA, Caplice N, O'Brien T, Simari R, Dearani J, Mullany C, Orszulak T,Schaff H. ; (1999) 'The role of gene therapy for intimal hyperplasia of bypass grafts' [Details]
(1999)'Regulation of caveolin expression and localization in smooth muscle cells'
Peterson T, Kleppe L, Caplice N, Mueske C, Pan S, Simari R. ; (1999) 'Regulation of caveolin expression and localization in smooth muscle cells' [Details]
(1998)'New insights into the mechanisms of thrombogenesis in atherosclerosis'
Caplice NM, Simari RD; (1998) 'New insights into the mechanisms of thrombogenesis in atherosclerosis' [Details]
(1998)'The Role of Tissue Factor in Vascular Disease'
Caplice NM, Simari RD. . ; (1998) 'The Role of Tissue Factor in Vascular Disease' [Details]
(1998)'Expression of tissue factor pathway inhibitor in vascular smooth muscle cells and its regulation by growth factors'
Caplice NM, Mueske CS, Kleppe LS, Peterson TE, Broze GJ, Simari RD. ; (1998) 'Expression of tissue factor pathway inhibitor in vascular smooth muscle cells and its regulation by growth factors' [Details]
(1998)'Modification of molecular events in coronary restenosis using coated stents. The Mayo Clinic Approach'
Keelan PC, Miyauchi K, Caplice NM, Ashai KH, Schwartz RS.; (1998) 'Modification of molecular events in coronary restenosis using coated stents. The Mayo Clinic Approach' [Details]
(1998)'The presence of tissue factor pathway inhibitor in human atherosclerotic plaques is associated with reduced tissue factor activity'
Caplice NM, Mueske CS, Kleppe LS, Simari RD. ; (1998) 'The presence of tissue factor pathway inhibitor in human atherosclerotic plaques is associated with reduced tissue factor activity' [Details]
(1997)'Growth factors released into the coronary circulation after vascular injury promote proliferation of human vascular smooth muscle cells in culture'
Caplice NM, CN Aroney, JHN Bett, J Cameron, J Campbell, N Hoffmann, P McEniery, MJ West; (1997) 'Growth factors released into the coronary circulation after vascular injury promote proliferation of human vascular smooth muscle cells in culture' [Details]
(1995)'Rabbit models of atherosclerosis and restenosis'
Caplice NM, PA Fennessy, JA Manderson, GR Campbell, JH Campbell ; (1995) 'Rabbit models of atherosclerosis and restenosis' [Details]
(1994)'Inhibition of human vascular smooth muscle growth by heparin'
Caplice NM, MJ West, GR Campbell, J Campbell ; (1994) 'Inhibition of human vascular smooth muscle growth by heparin' [Details]

Other Journals

YearPublication
(2011)'New therapeutic potential of microRNA treatment to target vulnerable atherosclerotic lesions and plaque rupture'
Martin K, O'Sullivan JF, Caplice NM (2011) 'New therapeutic potential of microRNA treatment to target vulnerable atherosclerotic lesions and plaque rupture' Current Opinion in Cardiology, 26 (6) :569-575. [Details]

Conference Publications

YearPublication
(2013)American Heart Association (AHA), BCVS, Las Vegas, USA, 2013
Turner EC, Huang CL, Sawhney N, Govindarajan K, Kumar AHS, Clover JP, Martin K, Leblond AL, Wang S, and Caplice NM (2013) Identification of a novel adult smooth muscle-like stem/progenitor cell that facilitates formation of tissue engineered vascular tissue for use as vascular grafts in vivo American Heart Association (AHA), BCVS, Las Vegas, USA, 2013 [Details]
(2011)American College of Cardiology, Winner Cardiovascular Pharmacology YIA
John F. O'Sullivan, Anne-Laure Leblond, Pat Metharom, Arun HS Kumar, Geraldine Kelly, Eva Hristova, Brian Hynes, Rosemary O'Connor, and Noel M. Caplice (2011) POTENT CARDIOPROTECTIVE EFFECTS OF LOW DOSE INSULIN-LIKE GROWTH FACTOR-1 (LD-IGF-1) TREATMENT POST MYOCARDIAL INFARCTION ARE MEDIATED THROUGH PHOSPHORYLATION OF THE IGF-1 RECEPTOR, GSK-3BETA INHIBITION AND SURVIVAL KINASE UPREGULATION- American College of Cardiology, Winner Cardiovascular Pharmacology YIA [Details]
(2011)Atherosclerosis Thrombosis and Vascular Biology Conference, 28th--‐30th April 2011. Hilton, Chicago, Illinois,USA
Pat Metharom, Kenneth Martin, Arun HS Kumar, Noel M Caplice. (2011) Pleiotropic Role for Monocyte C--‐fms Protein in Response to Vascular Injury:= Potential Therapeutic Target Atherosclerosis Thrombosis and Vascular Biology Conference, 28th--‐30th April 2011. Hilton, Chicago, Illinois,USA [Details]
(2011)American Heart Association - Finalist Melvin Judkins YIA
John F O'Sullivan, Anne-Laure Leblond, John O'Dea, Ivalina Hristova, Sujith Kumar, Noel M Caplice, (2011) Multi Detector CT Accurately Defines Infarct Size, but not Microvascular Obstruction Post Myocardial Infarction, and Sodium Nitrite Increases Microvascular Obstruction Region Blood Flow Without Affecting CT Hypoenchancement Area American Heart Association - Finalist Melvin Judkins YIA [Details]
(2011)Atherosclerosis Thrombosis and Vascular Biology Conference, 28th--‐30th April 2011. Hilton, Chicago, Illinois,USA
HS Kumar, Kenneth Martin, Noel M Caplice (2011) Deficiency Of CX3CR1 Receptors Results in Formation of Leaky Microvessels in Plaque Atherosclerosis Thrombosis and Vascular Biology Conference, 28th--‐30th April 2011. Hilton, Chicago, Illinois,USA [Details]
(2011)Irish Cardiac Society, Winner YIA
John F O’Sullivan, M.D., Anne-Laure Leblond, PhD, Geraldine Kelly, BSc, Arun HS Kumar DVM, PhD, Pat Metharom, PhD, Chirlei K Büneker, PhD, Niki Alizadeh-Vikali, MSc, BHSc, Ivalina Hristova, BS, Brian G Hynes, M.D., Rosemary O’Connor, PhD, Noel M Caplice, (2011) Potent Long-term Cardioprotective Effects of Single Low Dose Insulin-like Growth Factor-1 (LD-IGF-1) Treatment Post Myocardial Infarction Irish Cardiac Society, Winner YIA [Details]
(2008)Arteriosclerosis, thrombosis and vascular biology annual conference AHA 2008
"Smooth Muscle Progenitors Cells and Vascular Disease-The Plot Thickens" ; (2008) Smooth Muscle Progenitors Cells and Vascular Disease-The Plot Thickens Arteriosclerosis, thrombosis and vascular biology annual conference AHA 2008 Atlanta Georgia, , 01-APR-08 - 30-APR-08 [Details]
(2007)Life Sciences 2007
Pierce W, Murphy SC, Metharom P, Sheehan D, Caplice NM, Mackrill JJ.; (2007) Calcium signalling in vascular stem cells Life Sciences 2007 Glasgow, [Details]
(2007)Life Sciences 2007
Pierce WG, Murphy SC, Sheehan D, Caplice NM, Mackrill JJ.; (2007) Atypical calcium responses evoked by fibrinogen in vascular stem cells Life Sciences 2007 Glasgow, [Details]
(2007)Royal Academy of Medicine in Ireland, Section of Biomedical Sciences, Summer Meeting
Pierce W, Caplice NM, Metharom P, Mackrill JJ. ; (2007) Atypical Ca2+ responses to fibrinogen in endothelial progenitor cells Royal Academy of Medicine in Ireland, Section of Biomedical Sciences, Summer Meeting Ireland, [Details]

Conference Contributions

YearPublication
(2010)Irish Cardiac Society Meeting,
Professor Noel Caplice; (2010) Irish Cardiac Society Meeting. [Conference Organising Committee Chairperson], Irish Cardiac Society Meeting, Sligo, Ireland , 08-OCT-10 - 08-OCT-10
(2010)Discovery to Delivery,
Professor Noel Caplice; (2010) Chair at the ¿Translational Medicine 2010:Discovery to DeliveryDiscovery to Delivery. [Conference Organising Committee Chairperson], Discovery to Delivery, Trinity College, Dublin, Ireland, , 07-OCT-10 - 07-OCT-10
(2010)Experimental acquisitions of cell therapy in STEMI,
Professor Noel Caplice; (2010) Experimental acquisitions of cell therapy in STEMI. [Invited Seminars/Guest Lectures], Experimental acquisitions of cell therapy in STEMI, 1st International ¿Lario¿ Meeting on Cardiovascular Regenerative Medicine: , 11-JUN-10 - 12-JUN-10
(2010)Scientific Sessions, American Heart Association Meeting,
Professor Noel Caplice; (2010) Scientific Sessions, American Heart Association Meeting. [Invited Seminars/Guest Lectures], Scientific Sessions, American Heart Association Meeting, Chicago, USA , 13-NOV-10 - 17-NOV-10
(2010)Health Research Board / Irish Medical Devices Association,
Professor Noel Caplice; (2010) Primitive vascular progenitor cells in atherosclerosis¿. [Conference Organising Committee Chairperson], Health Research Board / Irish Medical Devices Association, Dublin , 28-OCT-10 - 28-OCT-10
(2009)Vascular progenitor cells in cardiovascular disease¿a new frontier,
Professor Noel Caplice; (2009) Vascular progenitor cells in cardiovascular disease¿a new frontier. [Invited Seminars/Guest Lectures], Vascular progenitor cells in cardiovascular disease¿a new frontier, 60th Annual Scientific Meeting of the Irish Cardiac Society, Kerry, Ireland , 08-OCT-09 - 09-OCT-09
(2009)The role of progenitor cells in cardiac repair,
Professor Noel Caplice; (2009) The role of progenitor cells in cardiac repair. [Invited Seminars/Guest Lectures], The role of progenitor cells in cardiac repair, Prague, Czech Rep , 11-OCT-09 - 14-OCT-09
(2009)Stem cells for ischemic disease and angiogenesis,
N. Caplice; (2009) Stem cells for ischemic disease and angiogenesis. [Invited Seminars/Guest Lectures], Stem cells for ischemic disease and angiogenesis, British Microcirculation Society, Birmingham, UK , 30-MAR-09 - 31-MAR-09
(2008)Translational Imaging - New Insights into Cardiovascular Disease,
; (2008) Translational Imaging - New Insights into Cardiovascular Disease. [Oral Presentation], Translational Imaging - New Insights into Cardiovascular Disease, Cork , 01-SEP-08 - 30-SEP-08
(2008)Repair therapy for the myocardium after acute MI,
Repair therapy for the myocardium after acute MI; (2008) Repair therapy for the myocardium after acute MI. [Oral Presentation], Repair therapy for the myocardium after acute MI, A.Menarini National CHF Symposium for Hospital Doctors , 01-APR-08 - 30-APR-08
(2008)Hemodynamics for the cardiology Trainee,
Hemodynamics for the cardiology Trainee ; (2008) Hemodynamics for the cardiology Trainee Organiser/ Director. [Conference Organising Committee Member], Hemodynamics for the cardiology Trainee, Cork , 01-JUL-08 - 31-JUL-08
(2008)Frontiers in Cardiovascular Medicine,
Frontiers in Cardiovascular Medicine ; (2008) Frontiers in Cardiovascular Medicine. [Conference Organising Committee Member], Frontiers in Cardiovascular Medicine, Cork , 01-DEC-08 - 20-DEC-08
(2008)Cell therapy for acute myocardial infarction:where are we in 2008? ,
Cell therapy for acute myocardial infarction:where are we in 2008? ; (2008) Cell therapy for acute myocardial infarction:where are we in 2008? . [Oral Presentation], Cell therapy for acute myocardial infarction:where are we in 2008? , Torino , 01-NOV-08 - 30-NOV-08
(2008)British Cardiovascular Forum,
British Cardiovascular Forum.; (2008) British Cardiovascular Forum. [Invited Oral Presentation], British Cardiovascular Forum, Duoro Portugal , 01-JUN-08 - 30-JUN-08
(2008)Arteriosclerosis, thrombosis and vascular biology annual conference AHA 2008,
"Smooth Muscle Progenitors Cells and Vascular Disease-The Plot Thickens" ¿Invited talk Arteriosclerosis, thrombosis and vascular biology annual conference AHA 2008.; (2008) Arteriosclerosis, thrombosis and vascular biology annual conference AHA 2008. [Oral Presentation], Arteriosclerosis, thrombosis and vascular biology annual conference AHA 2008, Atlanta Georgia , 01-APR-08 - 30-APR-08
(2003)First Mayo Clinic-Siebens Symposium on Stem Cell Therapy,
First Mayo Clinic-Siebens Symposium on Stem Cell Therapy ; (2003) First Mayo Clinic-Siebens Symposium on Stem Cell Therapy Co-director. [Conference Organising Committee Member], First Mayo Clinic-Siebens Symposium on Stem Cell Therapy, Mayo Clinic, Rochester, MN , 01-JAN-03 - 31-DEC-03

Abstract

YearPublication
(2012)Potent long-term cardioprotective effects of single low dose insulin-like growth factor-1 (LD-IGF-1) treatment post myocardial infarction.
O'sullivan, JF,Leblond, AL,Kelly, G,Kumar, AHS,Metharom, P,Buneker, CK,Alizadeh-Vikali, N,Hynes, BG,O'connor, R,Caplice, NM (2012) Potent long-term cardioprotective effects of single low dose insulin-like growth factor-1 (LD-IGF-1) treatment post myocardial infarction. Abstract [Details]
(2011)Monocyte recruitment via the CX3CR1 receptor influences burn wound healing.
Clover, AJP,Kumar, AHS,Caplice, NM (2011) Monocyte recruitment via the CX3CR1 receptor influences burn wound healing. Abstract [Details]
(2011)Downregulation of the chemokine receptor CX3CR1 in active RA associated with a pro-osteoclastogenic phenotype.
Murphy, G,Ryan, J,Harney, S,Shanahan, F,Molloy, M,Caplice, N (2011) Downregulation of the chemokine receptor CX3CR1 in active RA associated with a pro-osteoclastogenic phenotype. Abstract [Details]
(2011)Protection from collagen-induced arthritis in a CX3CR1 deficient mouse strain.
Murphy, G,Kumar, A,Shanahan, F,Harney, S,Molloy, M,Caplice, N (2011) Protection from collagen-induced arthritis in a CX3CR1 deficient mouse strain. Abstract [Details]
(2011)POTENT CARDIOPROTECTIVE EFFECTS OF LOW DOSE INSULIN-LIKE GROWTH FACTOR-1 (LD-IGF-1) TREATMENT POST MYOCARDIAL INFARCTION ARE MEDIATED THROUGH PHOSPHORYLATION OF THE IGF-1 RECEPTOR, GSK-3BETA INHIBITION AND SURVIVAL KINASE UPREGULATION.
O'Sullivan, JF,Leblond, AL,Metharom, P,Kumar, AHS,Kelly, G,Hristova, E,Hynes, B,O'Connor, R,Caplice, NM (2011) POTENT CARDIOPROTECTIVE EFFECTS OF LOW DOSE INSULIN-LIKE GROWTH FACTOR-1 (LD-IGF-1) TREATMENT POST MYOCARDIAL INFARCTION ARE MEDIATED THROUGH PHOSPHORYLATION OF THE IGF-1 RECEPTOR, GSK-3BETA INHIBITION AND SURVIVAL KINASE UPREGULATION. Abstract [Details]
(2011)PRO-OSTEOCLASTOGENIC PHENOTYPE OF MONOCYTE SUBSETS IN ACTIVE RA CHARACTERIZED BY DOWNREGULATION OF SURFACE CX3CR1.
Murphy, G,Ryan, J,Harney, S,Shanahan, F,Caplice, N,Molloy, M (2011) PRO-OSTEOCLASTOGENIC PHENOTYPE OF MONOCYTE SUBSETS IN ACTIVE RA CHARACTERIZED BY DOWNREGULATION OF SURFACE CX3CR1. Abstract [Details]
(2011)CX3CR1 DEFICIENCY RESULTS IN PROTECTION FROM COLLAGEN-INDUCED ARTHRITIS IN A TRANSGENIC MOUSE MODEL.
Murphy, G,Kumar, A,Shanahan, F,Harney, S,Molloy, M,Caplice, N (2011) CX3CR1 DEFICIENCY RESULTS IN PROTECTION FROM COLLAGEN-INDUCED ARTHRITIS IN A TRANSGENIC MOUSE MODEL. Abstract [Details]
(2010)TAKOTSUBO CARDIOMYOPATHY-A LARGE COHORT, MULTI CENTRE FOLLOW UP.
Kasim, S,Moran, D,O'Donnabhain, R,Cronin, E,Kerins, D,Vaughan, C,Kelly, P,Curtin, R,Caplice, N (2010) TAKOTSUBO CARDIOMYOPATHY-A LARGE COHORT, MULTI CENTRE FOLLOW UP. Abstract [Details]
(2009)Endothelial Progenitor Cell Derived Conditioned Media Reduces In Vivo Cardiomyocyte Apoptosis Acting Through TGFB1 and IGF1.
Hynes, B,Kumar, AHS,Weiss, S,Schmeckpeper, J,Murphy, G,Martin, K,O'Sullivan, J,McCauley, S,Caplice, NM (2009) Endothelial Progenitor Cell Derived Conditioned Media Reduces In Vivo Cardiomyocyte Apoptosis Acting Through TGFB1 and IGF1. Abstract [Details]
(2007)Molecular tracking of bone marrow progenitor differentiation in vitro.
Schmeckpeper, J,Caplice, N,Ikeda, Y (2007) Molecular tracking of bone marrow progenitor differentiation in vitro. Abstract [Details]
(2006)Vascular progenitor cells lineage controversies.
Caplice, N (2006) Vascular progenitor cells lineage controversies. Abstract [Details]

Book Review

YearPublication
(2012)Surface chemical and physical modification in stent technology for the treatment of coronary artery disease.
Nazneen, F,Herzog, G,Arrigan, DWM,Caplice, N,Benvenuto, P,Galvin, P,Thompson, M (2012) Surface chemical and physical modification in stent technology for the treatment of coronary artery disease. Book Reviews [DOI] [Details]
(2011)New therapeutic potential of microRNA treatment to target vulnerable atherosclerotic lesions and plaque rupture.
Martin, K,O'Sullivan, JF,Caplice, NM (2011) New therapeutic potential of microRNA treatment to target vulnerable atherosclerotic lesions and plaque rupture. Book Reviews [DOI] [Details]
(2011)Microribonucleic Acids for Prevention of Plaque Rupture and In-Stent Restenosis A Finger in the Dam.
O'Sullivan, JF,Martin, K,Caplice, NM (2011) Microribonucleic Acids for Prevention of Plaque Rupture and In-Stent Restenosis A Finger in the Dam. Book Reviews [DOI] [Details]
(2008)Fractalkine in rheumatoid arthritis: a review to date.
Murphy, G,Caplice, N,Molloy, M (2008) Fractalkine in rheumatoid arthritis: a review to date. Book Reviews [DOI] [Details]
(2007)Vascular disease: A new progenitor biology.
Metharom, P,Caplice, NM (2007) Vascular disease: A new progenitor biology. Book Reviews [Details]

Editorial

YearPublication
(2011)Role of Vessel Wall and Bone Marrow Syndecan-4 in Neointimal Hyperplasia The Plot Thickens.
Caplice, NM; (2011) Role of Vessel Wall and Bone Marrow Syndecan-4 in Neointimal Hyperplasia The Plot Thickens. Editorial [DOI] [Details]
(2010)Contrast-Enhanced Ultrasound and the Enigma of Plaque Neovascularization.
Caplice, NM,Martin, K; (2010) Contrast-Enhanced Ultrasound and the Enigma of Plaque Neovascularization. Editorial [DOI] [Details]

Honours and Awards

 YearTitleAwarding Body
1994Prince Charles Research Award, University of Queensland Prince Charles Research
1995Young Investigator Award-Ralph Reader Prize, Cardiac Society, Australia / NZ Cardiac Society Australia
1996Raymond Shanahan Prize in Cardiology, UCC UCC, Ireland
1998CR75 Award, Mayo Clinic Mayo Foundation Rochester MN
2003Gil Heat Institute Physician Scientist Award, University of Kentucky Lexington
2009Stokes Medal, Irish Cardiac Society Irish Cardiac Society, Ireland
2002MERCK Award, Athrosclerosis Research, USA MERCK
1992Merck Scholarship in Cardiology, Australian Heart Foundation Australian Heart Foundation

Associations

 AssocationFunctionFrom / To
NIH -NHLBI Study Taskfore on Stem Cell Trials, Washington, USA Inaugural taskforce member01-JUN-05 / 31-JUL-05
Illinois Regenerative Medicine Institute Chicago IL External advisor01-JUL-05 / 30-SEP-05
European Atherosclerosis Society Member/
Royal Collage of Physicians of Ireland Fellow/
Australasian College of Physicians Fellow/
Australian Cardiac Society Member/

Patents

 Patent NumberTitleInventorGranted
09/843, 295Mesh Stent for local drug-gene delivery Caplice et al.,01-JAN-05
P10378USPCSmooth muscle stem cells from peripheral blood Caplice et al01-JAN-08
7,790,493Smooth Muscle progenitor Cells Noel Caplice07-SEP-10

Employment

 EmployerPositionFrom / To
Centre for Reseach in Vascular Biology, UCC Professor/
Mayo Clinic Instructor in Medicine01-JAN-97 / 31-DEC-05
Mayo Clinic Consultant Cardiologist01-JAN-99 / 31-DEC-05
Mayo Clinic Asst. Professor01-JAN-01 / 31-DEC-05
Cork University Hospital Consultant Cardiologist30-SEP-05 /

Education

 YearInstituionQualificationSubject
1997University of Queensland, Brisbane, Austrailia. PHDbiology
1986University College Cork MB CHBMedicine

Consultancy

 ClientDescription
SAB member Edward Lifesciences Irvine CA

Teaching Interests

Undergraduate and graduate medical students-clinical cardiology
Doctorate and postdoctorate science graduates-vascular biology 
Core interests are in the areas of interventional cardiology as it relates to cardiac repair, vascular biology, vascular disease, translational medicine and novel therapeutics