Research Profile

Paula O'Leary

Biography

  • Graduated in Medicine from UCC 1987. MB, BCh, BAO Hons
  • Internship and General Professional Training in Medicine, Cork University Hospital, 1987 - 1991
  • Clinical Immunology Training ; St. James Hospital Dublin; Churchill Hospital, Oxford, UK and West Midlands Regional Immunology Training Scheme ( Hearlands Hospital, Birmingham, University of Birmingham), 1991 - 1997
  • Clinical Research Fellow and Honorary Lecturer, University of Birmingham, 1997 - 2000
  • Senior Clinical Tutor / Lecturer in Medicine Cork University Hospital, 2000 - 2003
  • Lecturer in Medicine / Locum Consultant Physician UCC and Cork University Hospital 2003 - 2005
  • Senior Lecturer in Medicine and Consultant Physician UCC and Cork University Hospital, 2005 - October 2016
  • Professor in Medicine (Lead Clinical Education) and Consultant Physician, November 2016 - Present 
  • Specialist Registration with Irish Medical Council in Clinical and Laboratory Immunology
  • Interests - Primary Immunodeficiency; Allergy Diagnosis and Treatment; Medical Education

Research Interests

  • Organisation and Delivery of Undergraduate / Pre-registration Medical Curricula
  • Clinical Education in Medicine and Clinical Immunology
  • New Teaching Methodologies
  • Primary Immunodeficiency; Immunoglobulin Therapies; Immunocompromise secondary to Medications
  • Allergy Diagnosis and Treatment

Publications

Books

 YearPublication
(2006)Concise Clinical Immunology for HealthCare Professionals.
Keogan MT, Wallace E, O'Leary P; (2006) Concise Clinical Immunology for HealthCare Professionals. United Kingdom: Taylor and Francis; Routledge. [Details]

Peer Reviewed Journals

 YearPublication
(2017)'Linitis Plastica of Muscle Fascia Presenting as Tiptoeing Gait'
O'Connor A;Kelly D;Gaughan M;Maher MM;O'Leary P;Bermingham N;Cronin S;O'Reilly S; (2017) 'Linitis Plastica of Muscle Fascia Presenting as Tiptoeing Gait'. Journal Of Oncology Practice, 13 (11) [DOI] [Details]
(2013)'Crohn's Disease: Has the Phenotype Changed?'
Bredin, E.,O'Leary, P.,Shanahan, F. (2013) 'Crohn's Disease: Has the Phenotype Changed?'. Gut, 62   [Details]
(2012)'Mesenteric vasculitis in adults with Henoch-Schonlein purpura: a not-so-benign condition'
Sibartie, V,O'Leary, P,Peirce, TH (2012) 'Mesenteric vasculitis in adults with Henoch-Schonlein purpura: a not-so-benign condition'. Irish Journal of Medical Science, 181 :269-271 [DOI] [Details]
(2004)'Failure to clear persistent vaccine-derived neurovirulent poliovirus infection in an immunodeficient man'
MacLennan, C;Dunn, G;Huissoon, AP;Kumararatne, DS;Martin, J;O'Leary, P;Thompson, RA;Osman, H;Wood, P;Minor, P;Wood, DJ;Pillay, D (2004) 'Failure to clear persistent vaccine-derived neurovirulent poliovirus infection in an immunodeficient man'. The Lancet, 363 :1509-1513 [Details]
(2002)'Aging and intestinal motility: a review of factors that affect intestinal motility in the aged. Drugs Aging'
O'Mahony, D.,O'Leary, P.,Quigley, E. M.; (2002) 'Aging and intestinal motility: a review of factors that affect intestinal motility in the aged. Drugs Aging'. Drugs & Aging, 19 (7):515-527   [Details]
(2002)'Food allergies'
O'Leary, Paula F. G. and Shanahan, Fergus (2002) 'Food allergies'. Current Gastroenterology Reports, 4 (5):373-82 [Details]
(1999)'Dendritic cells associated with plasmablast survival'
Garcia de Vinuesa C, Gulbranson Judge A, Khan M, O'Leary P, Cascalho M, Wabl M, Klaus GG, Owen MJ, MacLennan IC. (1999) 'Dendritic cells associated with plasmablast survival'. Eur J Immunol, 29 (11):3712-3721 [Details]
(1999)'Hepatic dysfunction in a population of antibody-deficient patients: prevalence, aetiology and outcome of PCR screening for hepatitis C and G viruses'
O'Leary PF, Collingham K, Skidmore S, King J, Bennett CL, WIlliams PE, Pillay D, Thompson RA. (1999) 'Hepatic dysfunction in a population of antibody-deficient patients: prevalence, aetiology and outcome of PCR screening for hepatitis C and G viruses'. Vox Sanguinis, 29 (4):144-148 [Details]
(1999)'T independant type 2 antigens induce B cell proliferation in multiple splenic sites, but exponential growth is confined to extrafollicular foci'
Garcia de Vinuesa C, O'Leary P, Sze DM, Toellner KM, MacLennan IC; (1999) 'T independant type 2 antigens induce B cell proliferation in multiple splenic sites, but exponential growth is confined to extrafollicular foci'. Eur J Immunol, 29 (4):1314-1323 [Details]
(1990)'Severe Oxprenolol poisoning: the importance of glucagon infusion'
O'Mahony D, O'Leary P, Molloy MG. (1990) 'Severe Oxprenolol poisoning: the importance of glucagon infusion'. Human and Experimental Toxicology, 9 (2):101-103 [Details]

Book Chapters

 YearPublication
(2016)'Immunological Disorders: immunodeficiencies and gastrointestinal complications of organ transplantation, Chapter 120'
O'Leary, P and Shanahan, F. (2016) 'Immunological Disorders: immunodeficiencies and gastrointestinal complications of organ transplantation, Chapter 120' In: Yamada's Textbook of Gastroenterology. Sixth Edition, Volume 2. USA: Wiley Blackwell. [Details]
(2016)'Gastrointestinal Manifestations of Immunological Disorders. Chapter 65'
O'Leary, P and Shanahan, F. (2016) 'Gastrointestinal Manifestations of Immunological Disorders. Chapter 65' In: Yamada's Atlas of Gastroenterology. Fifth Edition. USA: Wiley Blackwell. [Details]

Conference Publications

 YearPublication
(2012)Irish Network of Medical Educators
Storan,D;O'Leary,P;O`Flynn,S;Kelly,M (2012) Are newly qualified medical graduates prepared for practice? Irish Network of Medical Educators , pp.41-41   [Details]

Professional Activities

Honours and Awards

 YearTitleAwarding Body
2016NDTP Development Fund Award: The Intern Clinical Learning Environment - A Pilot STudy of Baseline Intern Post Performance and Targeted Improvement Strategies in Intern Network South HSE
2015Site receuitment by Quintiles Ltd. to manage HyQvia Pass post authorisation safety study at Cork University Hospital QUINTILES LTD.
2014Windle Award University College Cork
1996Sheldon Fellowship....NHS Research Fellow Award NHS, Britian

Professional Associations

 AssociationFunctionFrom / To
UK Primary Immunodeficiency Network (UKPIN) Member/
Immunology and Allergy Association of Ireland (IAAI) Member/
Corrigan Club Member/
APC Microbiome Institute UCC Faculty Member/
European Society for Immunodeficiencies (ESID) Member/
Irish Network for Medical Educators (INMED) Member/

Conference Contributions

 YearPublication
(2017)Irish Association of Dermatologists Contact Dermatitis Course. Testing for Drug Allergy,
O'Leary Paula (2017) Testing for Drug Allergy. [Other], Irish Association of Dermatologists Contact Dermatitis Course. Testing for Drug Allergy, South Infirmary-Victoria University Hospital Cork . [Details]
(2016)Penicillin Allergy - Points for busy doctors,
O'Leary Paula (2016) Penicillin Allergy. [Invited Lectures (Conference)], Penicillin Allergy - Points for busy doctors, Mercy University Hospital Grand Rounds . [Details]
(2016)Corrigan Club Meeting,
O'Leary Paula (2016) Medical Education.....looking backwards; looking forwards. [Invited Lectures (Conference)], Corrigan Club Meeting, University College Cork . [Details]
(2015)Grand Rounds,
O'Leary Paula (2015) Allergic Reactions in the Hospital Setting. [Invited Lectures (Conference)], Grand Rounds, Bon Secours Hospital Cork . [Details]
(2013)Cork City GP Educational Meeting,
O'Leary Paula (2013) Allergic Rhinitis and its Management. [Invited Lectures (Conference)], Cork City GP Educational Meeting, Cork . [Details]
(2013)Immunology and Allergy Association of Ireland,
O'Leary Paula (2013) Long-standing complications in antibody deficiency. [Invited Lectures (Conference)], Immunology and Allergy Association of Ireland, Kildare . [Details]
(2013)North Cork GP Educational Meeting,
O'Leary Paula (2013) Allergic Disease and Allergy Testing for GPs. [Invited Lectures (Conference)], North Cork GP Educational Meeting, Cork . [Details]
(2012)Experience of Illness,
O'Leary Paula (2012) Larning from the Arts. [Invited Lectures (Conference)], Experience of Illness, APC Microbiome Institute UCC . [Details]
(2011)Immunology and Allergy Association of Ireland,
O'Leary Paula (2011) Exercise-associated urticaria. Case reports and discussion group. [Invited Lectures (Conference)], Immunology and Allergy Association of Ireland, Moate, Co.Westmeath . [Details]
(2010)Royal College of Physicians of Ireland. Clinical Updates,
O'Leary Paula (2010) The role of Immunoglobulin Therapy in Immunodeficiency States. [Invited Lectures (Conference)], Royal College of Physicians of Ireland. Clinical Updates, Dublin . [Details]
(2010)West Cork GP Educational Meeting,
O'Leary Paula (2010) Use of the Immunology Laboratory for GPs. [Invited Lectures (Conference)], West Cork GP Educational Meeting, Dunmanway, Co. Cork . [Details]
(2009)Immunology and Allergy Association of Ireland,
O'Leary Paula (2009) Aspirin and NSAID Allergy. [Invited Lectures (Conference)], Immunology and Allergy Association of Ireland, Portarlington. Co. Laois . [Details]
(2007)UCC Grand Rounds,
O'Leary Paula (2007) Update on Medical Education at UCC. [Invited Lectures (Conference)], UCC Grand Rounds, Cork . [Details]
(2006)Annual Scientific Meeting, Faculty of Radiologists, RCSI,
O’Connor OJ, O’Flynn S, Lynch S, SpenceL, Ryan M, Kelly M, Barry J, Fitzgerald E, MacEneaney P, O’Donovan N, Kenny B, O' Brien P, O’Leary P, Quigley E, Shanahan F, Maher MM. (2006) Assessing competence in interpretation of Imaging studies during Final Medical Examination: Experience from University College Cork (UCC). [Oral Presentation], Annual Scientific Meeting, Faculty of Radiologists, RCSI, Dublin , 30-SEP-06 - 28-SEP-06. [Details]
(2006)UCC Medical Alumni Meeting,
O'Leary Paula (2006) Update on Medical Education at UCC. [Invited Lectures (Conference)], UCC Medical Alumni Meeting, Galway . [Details]
(2006)Immunology Advisory Body of the Academy of Clinical Sciences and Laboratory Medicine,
O'Leary Paula (2006) Immune Deficiency at the extremes of age. [Invited Lectures (Conference)], Immunology Advisory Body of the Academy of Clinical Sciences and Laboratory Medicine, Dublin . [Details]
(2004)SMA Nutrition National Education Meeting,
O'Leary Paula (2004) Making Sense of Food Allergy. [Invited Lectures (Conference)], SMA Nutrition National Education Meeting, Dublin . [Details]
(2003)UCC Medical Grand Rounds,
O'Leary Paula (2003) Immunology Today. [Invited Lectures (Conference)], UCC Medical Grand Rounds, Cork University Hospital . [Details]
(2003)SMA Nutrition National Education Meeting,
O'Leary Paula (2003) Current Concepts in Food Allergy. [Invited Lectures (Conference)], SMA Nutrition National Education Meeting, Cork . [Details]
(2002)Biochemistry Advisory Body of the Academy of Clinical Sciences and Laboratory Medicine,
O'Leary Paula (2002) A clinical review of paraproteinaemic states. [Invited Lectures (Conference)], Biochemistry Advisory Body of the Academy of Clinical Sciences and Laboratory Medicine, Cork . [Details]
(2002)Midwestern Hospitals Grand Rounds,
O'Leary Paula (2002) All about antibodies. [Invited Lectures (Conference)], Midwestern Hospitals Grand Rounds, Limerick . [Details]
(1997)British Society for Immunology Annual Congress,
O'Leary Paula (1997) The influences of T cells on responses to hapten-lipopolysaccharide. [Invited Lectures (Conference)], British Society for Immunology Annual Congress, Brighton, England . [Details]
(1996)European Society for Immunodeficiency Diseases (ESID),
O'Leary Paula (1996) Hepatitis C surveillance in a British cohort of patients with antibody deficiency. [Invited Lectures (Conference)], European Society for Immunodeficiency Diseases (ESID), Goteburg, Sweden . [Details]
(1992)International Coeliac Symposium,
O'Leary Paula (1992) Aphthous ulceration in the absence of coeliac disease. A gluten sensitive disorder?. [Invited Lectures (Conference)], International Coeliac Symposium, Dublin . [Details]
(1992)Joint Meeting of the Royal Academy of Medicine and Irish Society of Rheumatology and Rehabilitation Medicine,
O'Leary Paula (1992) Anti-phospholipid syndrome in a patient with renal impairment, liver abnormalities and an acute respiratory syndrome. [Invited Lectures (Conference)], Joint Meeting of the Royal Academy of Medicine and Irish Society of Rheumatology and Rehabilitation Medicine, Dublin . [Details]
(1992)Royal Academy of Medicine in Ireland. Annual Case Report Meeting,
O'Leary Paula (1992) Partial lipodystrophy: an important clinical indicator of complement deficiency. [Invited Lectures (Conference)], Royal Academy of Medicine in Ireland. Annual Case Report Meeting, Dublin . [Details]
(1991)Irish Nephrological Society Annual Meeting,
O'Leary Paula (1991) Antibiotic therapy in CAPD peritonitis. [Invited Lectures (Conference)], Irish Nephrological Society Annual Meeting, Dublin . [Details]

Committees

 CommitteeFunctionFrom / To
Immunology Advisory Group; National Clinical Programmes - Clinical Pathology Immunology Advisory Group/
National Intern Board 2018 Member/
HSE Expert Advisory Group on Antibiotic Use Lead in antibiotic allergy./
Board of Directors, Mercy University Hospital Member of Board of Directors and Member of the Clinical Oversight Committee/

Outreach Activities

 Description

Outreach to UCC medical graduates and friends though participation on UCC Medical Alumni/now Medical Graduate Association Committee (2003-Present)

External Representation for the School of Medicine in its interactions with other Irish Medical Schools through the Council of Irish Medical Schools (formerly Council of Deans of Irish Universities with Medical Schools) – a body setting strategy and key priorities for medical education in Ireland; Liaison with Irish Medical Council through National Intern Board and Council of Irish Medical Schools; Interaction with HEA on issues of mutual interest – admissions, numbers, standards. Representation of School at Ministerial Level (education) in order to inform government strategy with regard to medical education.

Department of Medicine and School of Medicine representation at local level internally and externally through University-wide committees and Hospital Executive Management boards.

Teaching Activities

Teaching Interests

  • Chair of Working Group for Clinical Medical School (March 2017-Present)
  • UCC Representative on Intern Network Executive (INE) (2015-Present)
  • Chair Curriculum Committee, UCC Medical School (2009-2014)
  • Member Teaching and Learning Committee, UCC College of Medicine and Health (2009-2014)
  • Member, INMED 
  • School of Medicine Representative to College of Medicine & Health Executive and to College of Medicine & Health Teaching and Learning Committees

Current Postgraduate Students

 StudentDegree Type
Coakley Niamh Una Doctoral Degree
Pope George Anthony Masters Degree by Research

Modules Taught

 Term (ID))TitleLinkSubject
2019Principles and Practice of Internal Medicine and General Practice CP5200Principles and Practice of Internal Medicine and General Practice

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Department of Medicine

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