Research Profile

Waleed Faisal

Biography

Dr. Waleed Faisal is a project manager and Creer-Fit fellow at the School of Pharmacy, University College Cork. He also, work as part-time lecturer at the Griffith College-Ireland. Dr. Faisal graduated with a degree in Pharmacy from Asyut University, Egypt.  In 2009, he completed a PhD in Pharmaceutics in the School of Pharmacy University College Cork. Dr. Faisal was employed as a postdoctoral researcher at the School of Pharmacy-UCC between 2010 and 2013 and as Lecture of Pharmaceutics at Minia University from 2013-2016. Since joining the School of Pharmacy in UCC in 2016, Dr. Faisal is actively involved in collaborative projects with pharmaceutical companies, both SME and multi-nationals.

Research Interests

Dr Faisal has 14 years of experience designing and executing multidisciplinary research projects within the field of pharmaceutical formulation science and manufacturing, and have a number of research papers published in these areas. He is involved in a leadership role within pharmaceutical development and commercialisation of the product, and he has been primarily working within the Quality Assurance aspect including exposure to GMP and regulatory aspects as well as R&D activities. The key focus of his research is the development and manufacture of effective, high quality, cost-effective medicinal products. This includes: ·        
  • Formulation and characterisation of microneedle drug delivery systems
  • Lipid-based formulations for enhancing oral bioavailability of poorly soluble drug compounds
  • Targeted drug delivery to the intestinal lymphatics ·        
  • Development of silica-based drug formulations to enhance the oral bioavailability of therapeutic compounds challenged by poor-water solubility.
Research metrics
https://orcid.org/0000-0002-9015-4008
https://www.researchgate.net/profile/Waleed_Faisal
https://www.linkedin.com/in/walid-faisal-4332425b/
https://scholar.google.com/citations?user=lysLcqIAAAAJ&hl=en

Research Grants

 ProjectFunding
Body
Start DateEnd DateAward
Microneedle as a new horizon drug delivery systemEnterprise Ireland01-MAR-2131-AUG-22€238,000.00
Novel formulation approaches to deliver antifungal medications to nailEnterprise Ireland01-FEB-1831-JUL-21€298,500.00
TARGETED DELIVERY OF ANTI-FUNGALS TO TREAT ONYCHOMYCOSIS (NAIL INFECTIONS)Enterprise Ireland01-SEP-1901-DEC-19€15,000.00
Delivery of Anti-Fungals to Treat Onchomycosis.Enterprise Irl01-AUG-1930-NOV-19€19,500.00

Publications

Peer Reviewed Journals

 YearPublication
(2020)'Silver Citrate Nanoparticles Inhibit PMA-Induced TNF alpha Expression via Deactivation of NF-kappa B Activity in Human Cancer Cell-Lines, MCF-7'
Abdellatif, AAH;Rasheed, Z;Alhowail, AH;Alqasoumi, A;Alsharidah, M;Khan, RA;Aljohani, ASM;Aldubayan, MA;Faisal, W (2020) 'Silver Citrate Nanoparticles Inhibit PMA-Induced TNF alpha Expression via Deactivation of NF-kappa B Activity in Human Cancer Cell-Lines, MCF-7'. International Journal of Nanomedicine, 15 :8479-8493 [DOI] [Details]
(2020)'Application of percolation threshold to disintegration and dissolution of ibuprofen tablets with different microcrystalline cellulose grades'
Queiroz A.L.P.;Wood B.;Faisal W.;Farag F.;Garvie-Cook H.;Glennon B.;Vucen S.;Crean A.M. (2020) 'Application of percolation threshold to disintegration and dissolution of ibuprofen tablets with different microcrystalline cellulose grades'. International Journal of Pharmaceutics, 589 [DOI] [Details]
(2019)'The application of percolation threshold theory to predict compaction behaviour of pharmaceutical powder blends'
Queiroz, Ana Luiza P.; Faisal, Waleed; Devine, Ken; Garvie-Cook, Hazel; Vucen, Sonja; Crean, Abina M. (2019) 'The application of percolation threshold theory to predict compaction behaviour of pharmaceutical powder blends'. Powder Technology, 354 :188-198   [DOI] [Full Text] [Details]
(2018)'Enhanced skin deposition and delivery of voriconazole using ethosomal preparations'
Faisal W;Soliman GM;Hamdan AM; (2018) 'Enhanced skin deposition and delivery of voriconazole using ethosomal preparations'. Journal Of Liposome Research, 28 (1) [DOI] [Details]
(2018)'Taste Masking Approaches for Medicines'
Faisal W;Farag F;Abdellatif AAH;Abbas A; (2018) 'Taste Masking Approaches for Medicines'. Current Drug Delivery, 15 (2) [DOI] [Details]
(2018)'Enalapril maleate orally disintegrating tablets: tableting and in vivo evaluation in hypertensive rats'
Tawfeek HM;Faisal W;Soliman GM; (2018) 'Enalapril maleate orally disintegrating tablets: tableting and in vivo evaluation in hypertensive rats'. Pharmaceutical Development And Technology, 23 (5) [DOI] [Details]
(2017)'In vitro dissolution models for the prediction of in vivo performance of an oral mesoporous silica formulation'
McCarthy, Carol A.; Faisal, Waleed; O'Shea, Joseph P.; Murphy, Colm; Aherne, Robert J.; Ryan, Katie B.; Griffin, Brendan T.; Crean, Abina M. (2017) 'In vitro dissolution models for the prediction of in vivo performance of an oral mesoporous silica formulation'. Journal Of Controlled Release, 250 :86-95   [DOI] [Full Text] [Details]
(2017)'Self-Assembling Organogels Based on Pluronic and Lecithin for Sustained Release of Etodolac: In Vitro and In Vivo Correlation'
Mohammed AM;Faisal W;Saleh KI;Osman SK; (2017) 'Self-Assembling Organogels Based on Pluronic and Lecithin for Sustained Release of Etodolac: In Vitro and In Vivo Correlation'. Current Drug Delivery, 14 (7) [DOI] [Details]
(2015)'Lipidic dispersion to reduce food dependent oral bioavailability of fenofibrate: In vitro, in vivo and in silico assessments'
O'Shea, JP;Faisal, W;Ruane-O'Hora, T;Devine, KJ;Kostewicz, ES;O'Driscoll, CM;Griffin, BT (2015) 'Lipidic dispersion to reduce food dependent oral bioavailability of fenofibrate: In vitro, in vivo and in silico assessments'. European Journal Of Pharmaceutics And Biopharmaceutics, 96 :207-216 [DOI] [Details]
(2014)'Comparison of in vitro tests at various levels of complexity for the prediction of in vivo performance of lipid-based formulations: case studies with fenofibrate'
Griffin BT, Kuentz M, Vertzoni M, Kostewicz ES, Fei Y, Faisal W, Stillhart C, O'Driscoll CM, Reppas C, Dressman JB (2014) 'Comparison of in vitro tests at various levels of complexity for the prediction of in vivo performance of lipid-based formulations: case studies with fenofibrate'. European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 86 (3):427-437 [DOI] [Details]
(2013)'A novel lipid-based solid dispersion for enhancing oral bioavailability of Lycopene - In vivo evaluation using a pig model'
Faisal, W;Ruane-O'Hora, T;O'Driscoll, CM;Griffin, BT (2013) 'A novel lipid-based solid dispersion for enhancing oral bioavailability of Lycopene - In vivo evaluation using a pig model'. International Journal of Pharmaceutics, 453 :307-314 [DOI] [Details]
(2010)'Bioavailability of lycopene in the rat: the role of intestinal lymphatic transport'
Faisal, W; O'Driscoll, CM; Griffin, BT; (2010) 'Bioavailability of lycopene in the rat: the role of intestinal lymphatic transport'. Journal of Pharmacy and Pharmacology, 62 (3):323-331 [DOI] [Details]

Conference Publications

 YearPublication
(2008)UK & Ireland Controlled Release Society (UKICRS)
Faisal, W., O'Driscoll, C.M., Griffin, B.T.; (2008) Investigation of Lycopene absorption mechanisms from the Gastro-intestinal tract of the rat UK & Ireland Controlled Release Society (UKICRS) [Details]
(2008)American Association of Pharmaceutical Scientists (AAPS)
Faisal, W., O'Driscoll, C.M., Griffin, B.T.; (2008) Solubility and Stability of lycopene in lipid based formulations American Association of Pharmaceutical Scientists (AAPS) [Details]
(2007)All Ireland School of Pharmacy Conference
Faisal W, O'Driscoll CM, Griffin BT; (2007) Comparison of the intestinal lymphatic transport of lycopene in anaesthetised rat from a range of lipid based formulations All Ireland School of Pharmacy Conference Dublin, Ireland, [Details]
(2007)Excipient Fest Ireland
Faisal W, O'Driscoll CM, Griffin BT; (2007) Comparison of the intestinal lymphatic transport of lycopene in anaesthetised rat Excipient Fest Ireland Cork, Ireland, , 19-JUN-07 - 20-JUN-07 [Details]

Reviews

 YearPublication
(2018)Somatostatin receptors as a new active targeting sites for nanoparticles.
Abdellatif, AAH;Aldalaen, SM;Faisal, W;Tawfeek, HM (2018) Somatostatin receptors as a new active targeting sites for nanoparticles. AMSTERDAM: Reviews [DOI] [Details]
(2018)Taste Masking Approaches for Medicines.
Faisal, W;Farag, F;Abdellatif, AAH;Abbas, A (2018) Taste Masking Approaches for Medicines. SHARJAH: Reviews [DOI] [Details]

Professional Activities

Honours and Awards

 YearTitleAwarding Body
2020Short listed of the 2020 Entrepreneurship UCC, Ireland
2020Staff Training Visits Erasmus
2019Staff Training Visits Erasmus
2019Digital Badge for the Enhancement of Teaching and Learning in Higher Education National Forum, Ireland
2017Best poster in 3rd knowledge day Pharmaceutical Manufacturing Technology Centre
2017Career-Fit fellow Marie Sklodowska Curie Career-FIT Programme
20071st Gold medal and prize for best poster Excipient fest, Ireland
2005PhD Studentship Ministry of Higher Education, Egypt

Professional Associations

 AssociationFunctionFrom / To
AAPS American Association of Pharmaceutical Scientists Member01-JAN-18 / 01-FEB-21
Egyptian Pharmacist syndicate Member01-JUL-97 / 01-FEB-21

Patents

 Patent NumberTitleGranted
WO 2020/250210Microneedles, and methods for the manufacture thereof 17-DEC-20
GP1908229.6.Microneedles, and methods for the manufacture thereof 01-MAY-19

Conference Contributions

 YearPublication
(2018)EUPAT 2018,
Waleed Faisal, Ana Luiza Pinto Queiroz, Abina M. Crean (2018) The impact microcrystalline cellulose variable on Ibuprofen dissolution from direct compression tablets. [Invited Lectures (Conference)], EUPAT 2018, Manchester, UK , 15-MAY-18 - 16-MAY-18. [Details]
(2018)EUPAT 2018,
Ana Luiza Pinto Queiroz, Waleed Faisal and Abina M. Crean (2018) Application of the percolation threshold model in the design of robust direct compression tablet formulations. [Oral Presentation], EUPAT 2018, Manchester, UK , 15-MAY-18 - 16-MAY-18. [Details]
(2016)EuPAT8,
McCarthy C., Faisal W., O'Shea J., Murphy C., Griffin B., Crean A. (2016) In-vitro models for the prediction of in-vivo performance of a mesoporous silica formulation. [Poster Presentation], EuPAT8, Cork, Ireland , 03-OCT-16 - 04-OCT-16. [Details]
(2008)The AAPS Annual Meeting,
W. Faisal, C.M. O'Driscoll, B. Griffin ; (2008) Solubility and stability of lycopene in lipid-based formulations. [Oral Presentation], The AAPS Annual Meeting, Atlanta, USA , 15-NOV-08 - 15-NOV-08. [Details]
(2007)The 3rd Pharmaceutical Sciences World Congress PSWC,
W. Faisal, C.M. O'Driscoll, B. Griffin; (2007) Investigations of the mechanisms of absorption of lycopene from the gastro-intestinal tract of the rat. [Oral Presentation], The 3rd Pharmaceutical Sciences World Congress PSWC, Amsterdam , 25-APR-07 - 25-APR-07. [Details]

Committees

 CommitteeFunctionFrom / To
Solid State Pharmaceutical Centre SSPC diversity steering committee Member2020 / 2021
Athena Swan committee, School of pharmacy, UCC Member2018 / 2021
Department of Pharmaceutics, Minia University, Egypt Member2014 / 2016
Pharmaceutical and Herbal Preparation Unit, Minia University Chair2014 / 2016

Employment

 EmployerPositionFrom / To
University College Cork, Ireland Demonstrator01-MAY-05 / 17-JUN-09
University College Cork, Ireland Postdoctoral researcher01-JAN-10 / 30-MAY-13
Minia University, Egypt Lecturer Assistant01-MAR-99 / 27-APR-05
Minia University, Egypt Lecturer Pharmaceutics15-JUN-13 / 11-AUG-16
University College Cork, Ireland Postdoctoral researcher01-DEC-16 / 31-JAN-18
Xeolas Pharmaceutical company, Ireland Quality Assurance visiting researcher01-SEP-19 / 31-DEC-19

Education

 YearInstitutionQualificationSubject
2009University College Cork, Ireland PhDPharmaceutical Sciences (Pharmaceutics)
2002Minia University, Egypt MScPharmaceutical Sciences (Pharmaceutics)
1997Asyut University, Egypt BachelorPharmacy
2020NUI Galway, Ireland Postgraduate CerttificateFundamentals in Medical Device Design and Regulation
2019University College Cork, Ireland Postgraduate CerttificateTeach & Learning in Higher Ed
2019University College Cork, Ireland Postgraduate CerttificateClinical Trials

Languages

 LanguageReadingWritingSpeaking
English FluentFluentFluent
Arabic FluentFluentFluent

Outreach Activities

 Description

Organized by Enterprise Ireland June 2019.

Actively participate in press and Media programmes in RTE

Exhibited Microneedle Research at EU Innovation Days Exhibition, Science is Wonderful, Brussel, May 2019

Organized by Enterprise Ireland June 2020.

Journal Activities

 JournalRoleTo / From
Current Drug Delivery Referee-
International Journal Of Pharmaceutics Referee-

Other Activities

 Description

Yellow lean belt, 2018.  The essential Lean tools and practices that can be applied within the University to increase service efficiency and quality, improve student/staff/customer satisfaction and reduce waste.

Chair the first School of Pharmacy Research Day, May 2019.

Teaching Activities

Teaching Interests

I have gained extensive experience as an academic at a number of different universities. During my academic career, as a lecturer, I have responsibility for teaching and assessment on a range of undergraduate and postgraduate programmes.
  • Awarded a Postgraduate Cert in Teaching & Learning in Higher Education, UCC, Ireland, 2019.
  • Involved in developing delivering and regular evaluation of a new programme of Quality & Regulatory Framework in the Pharmaceutical Industry for the international master students, Griffith College, Ireland 2018-present
  • Programmes taught include Physical pharmacy; Topical and vaginal drug delivery systems; Biopharmaceutics and Clinical Pharmacokinetics; and Hospital Pharmacy. I was also involved in the setting of exams and grading
  • Setting of Exams and Grading at both undergraduate and postgraduate level.

Research Information

Internal Collaborators

 NameInstituteCountry
Anne Moore University College CorkIRELAND
Dr. Conor O'Mahony Tyndall institute of TechnologyIRELAND
Abina Crean University College CorkIRELAND

External Collaborators

 NameOrganisation / InstituteCountry
Prof. Ryan Donnelly Queen Belfast UniversityUNITED KINGDOM
Dr Sudax Murdan. University College LondonUNITED KINGDOM

Contact details

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School of Pharmacy

Cógaisíocht

Cavanagh Pharmacy Building Room UG06 University College Cork

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