Research Profile

Biography

Research Interests


  • Optimal prescribing and optimised dosage regimen design
  • Pharmacokinetic modelling 
  • Paediatric medicine
  • Pharmacogenetic-guided prescribing
  • Deprescribing

Publications

Peer Reviewed Journals

 YearPublication
(2023)'Multidisciplinary DEprescribing review for Frail oldER adults in long-term care (DEFERAL): Implementation strategy design using behaviour science tools and stakeholder engagement'
Heinrich CH;McHugh S;McCarthy S;Curran GM;Donovan MD; (2023) 'Multidisciplinary DEprescribing review for Frail oldER adults in long-term care (DEFERAL): Implementation strategy design using behaviour science tools and stakeholder engagement'. Research In Social & Administrative Pharmacy : Rsap, [DOI] [Details]
(2023)'Identification of Potentially Inappropriate Medications in Frail Older Adults Residing in Long-Term Care: A Retrospective Chart Review Study'
Heinrich, Clara H.,McCarthy, Suzanne,McHugh, Sheena,Donovan, Maria D.,Deprescribing is associated with positive health outcomes for older adults in long-term care (LTC), however deprescribing is not universally implemented. (2023) 'Identification of Potentially Inappropriate Medications in Frail Older Adults Residing in Long-Term Care: A Retrospective Chart Review Study'. Drugs - Real World Outcomes, 10 (1):97-106   [Details]
(2022)'Barriers and enablers to deprescribing in long-term care: A qualitative investigation into the opinions of healthcare professionals in Ireland'
Donovan, Maria D. (2022) 'Barriers and enablers to deprescribing in long-term care: A qualitative investigation into the opinions of healthcare professionals in Ireland'. PLOS ONE, 17 (12)   [Details]
(2021)'The Prevalence of and Documented Indications for Antipsychotic Prescribing in Irish Nursing Homes'
Kelleher J, Weedle P, Donovan M. (2021) 'The Prevalence of and Documented Indications for Antipsychotic Prescribing in Irish Nursing Homes'. [Details]
(2020)'Perspectives of Pharmacists on Facilitating Experiential Learning Placements for Pharmacy Students in Non Patient Facing Settings'
Donovan MD, Byrne EM, Griffin BT. (2020) 'Perspectives of Pharmacists on Facilitating Experiential Learning Placements for Pharmacy Students in Non Patient Facing Settings'. Currents in Pharmacy Teaching and Learning, [DOI] [Full Text] [Details]
(2018)'Application of a Physiologically-Based Pharmacokinetic Model for the Prediction of Bumetanide Plasma and Brain Concentrations in the Neonate'
Donovan, Maria D.; Abduljalil, Khaled; Cryan, John F.; Boylan, Geraldine B.; Griffin, Brendan T. (2018) 'Application of a Physiologically-Based Pharmacokinetic Model for the Prediction of Bumetanide Plasma and Brain Concentrations in the Neonate'. Biopharmaceutics & Drug Disposition, 39 :125-134 [DOI] [Full Text] [Details]
(2016)'In vitro bidirectional permeability studies identify pharmacokinetic limitations of NKCC1 inhibitor bumetanide'
Donovan, MD;Schellekens, H;Boylan, GB;Cryan, JE;Griffin, BT (2016) 'In vitro bidirectional permeability studies identify pharmacokinetic limitations of NKCC1 inhibitor bumetanide'. European Journal of Pharmacology, 770 :117-125 [DOI] [Details]
(2016)'Pharmacotherapy for Neonatal Seizures: Current Knowledge and Future Perspectives'
Donovan, Maria D.; Griffin, Brendan T.; Kharoshankaya, Liudmila; Cryan, John F.; Boylan, Geraldine B. (2016) 'Pharmacotherapy for Neonatal Seizures: Current Knowledge and Future Perspectives'. Drugs, 76 :647-661 [DOI] [Full Text] [Details]
(2015)'The effect of organic anion transporter 3 inhibitor probenecid on bumetanide levels in the brain: an integrated in vivo microdialysis study in the rat'
Donovan, MD;O'Brien, FE;Boylan, GB;Cryan, JF;Griffin, BT (2015) 'The effect of organic anion transporter 3 inhibitor probenecid on bumetanide levels in the brain: an integrated in vivo microdialysis study in the rat'. Journal of Pharmacy and Pharmacology, 67 :501-510 [DOI] [Details]
(2014)'The P-glycoprotein inhibitor cyclosporin A differentially influences behavioural and neurochemical responses to the antidepressant escitalopram'
O'Brien, FE;O'Connor, RM;Clarke, G;Donovan, MD;Dinan, TG;Griffin, BT;Cryan, JF (2014) 'The P-glycoprotein inhibitor cyclosporin A differentially influences behavioural and neurochemical responses to the antidepressant escitalopram'. Behavioural Brain Research, 261 :17-25 [DOI] [Details]

Reviews

 YearPublication
(2016)Treating disorders of the neonatal central nervous system: pharmacokinetic and pharmacodynamic considerations with a focus on antiepileptics.
Donovan, MD;Boylan, GB;Murray, DM;Cryan, JF;Griffin, BT (2016) Treating disorders of the neonatal central nervous system: pharmacokinetic and pharmacodynamic considerations with a focus on antiepileptics. HOBOKEN: Reviews [DOI] [Details]
(2016)Pharmacokinetic, pharmacodynamic and biodistribution following oral administration of nanocarriers containing peptide and protein drugs.
Griffin, BT;Guo, JF;Presas, E;Donovan, MD;Alonso, MJ;O'Driscoll, CM (2016) Pharmacokinetic, pharmacodynamic and biodistribution following oral administration of nanocarriers containing peptide and protein drugs. AMSTERDAM: Reviews [DOI] [Details]

Professional Activities

Honours and Awards

 YearTitleAwarding Body
2018Top Downloaded Article 2017-2018 Biopharmaceutics and Drug Disposition Wiley
2017Irish Pharmacy News Top 100 Dynamic Pharmacists 2017 Irish Pharmacy News

Professional Associations

 AssociationFunctionFrom / To
Pharmaceutical Society of Ireland MPSI/
European Society of Clinical Pharmacy Member/

Education

 YearInstitutionQualificationSubject
2012RCSI MPharmPharmacy
2016UCC PhDPharmaceutics
2011UCC BPharmPharmacy

Teaching Activities

Teaching Interests

  • Clinical Pharmacokinetics
  • Therapeutic Drug Monitoring
  • Case-based learning in Clinical Pharmacy
  • Minor ailments
  • Statistics and Research Methods
  • Pharmacogenetics
  • Deprescribing

Contact details


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School of Pharmacy

Cógaisíocht

Cavanagh Pharmacy Building Room UG06 University College Cork

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