Research Profile

Patrick O'Dwyer

Biography

Dr. Patrick O'Dwyer is currently a lecturer in Pharmaceutics at the School of Pharmacy in University College Cork. He received his Bachelor of Pharmacy (BPharm) degree from University College Cork in 2015 and completed his Master of Pharmacy (MPharm) degree from the Royal College of Surgeons in Ireland in 2016.

Dr. O'Dwyer completed his PhD in 2020 as part of the PEARRL (Pharmaceutical Education And Research with Regulatory Links) project, a European Training Network funded under the EU Horizon 2020 research and innovation programme (Marie Sklodowska-Curie actions). His PhD research was conducted in both Pion Inc. (UK) Ltd. and the National and Kapodistrian University of Athens, with a secondment in the European Medicines Agency also completed as part of the project.

Research Interests

  • Biorelevant dissolution testing
  • Physiologically based pharmacokinetic (PBPK) modeling
  • Regulatory Science
  • Novel approaches to enhance oral drug delivery


Publications

Peer Reviewed Journals

 YearPublication
(2020)'On the Usefulness of Two Small-Scale In Vitro Setups in the Evaluation of Luminal Precipitation of Lipophilic Weak Bases in Early Formulation Development'
O'Dwyer PJ;Imanidis G;Box KJ;Reppas C; (2020) 'On the Usefulness of Two Small-Scale In Vitro Setups in the Evaluation of Luminal Precipitation of Lipophilic Weak Bases in Early Formulation Development'. Pharmaceutics, 12 (3) [DOI] [Details]
(2020)'Novel Biphasic Lipolysis Method To Predict in Vivo Performance of Lipid-Based Formulations'
O'Dwyer PJ;Box KJ;Koehl NJ;Bennett-Lenane H;Reppas C;Holm R;Kuentz M;Griffin BT; (2020) 'Novel Biphasic Lipolysis Method To Predict in Vivo Performance of Lipid-Based Formulations'. Molecular Pharmaceutics, [DOI] [Details]
(2019)'In vitro methods to assess drug precipitation in the fasted small intestine - a PEARRL review'
O'Dwyer PJ;Litou C;Box KJ;Dressman JB;Kostewicz ES;Kuentz M;Reppas C; (2019) 'In vitro methods to assess drug precipitation in the fasted small intestine - a PEARRL review'. Journal of Pharmacy and Pharmacology, 71 (4) [DOI] [Details]
(2019)'Biphasic drug release testing coupled with diffusing wave spectroscopy for mechanistic understanding of solid dispersion performance'
Jankovic S.;O'Dwyer P.;Box K.;Imanidis G.;Reppas C.;Kuentz M. (2019) 'Biphasic drug release testing coupled with diffusing wave spectroscopy for mechanistic understanding of solid dispersion performance'. European Journal of Pharmaceutical Sciences, 137 [DOI] [Details]

Conference Publications

 YearPublication
(2019)AAPS Annual Meeting
O’Dwyer P.J., Koehl N.J., Box K.J., Griffin B.T., Holm R., Kuentz M., Reppas C. (2019) Novel Biphasic Lipolysis Testing of Nilotinib Lipid-Based Suspensions to Predict In Vivo Performance AAPS Annual Meeting [Details]
(2019)AAPS Annual Meeting
O’Dwyer P.J., Box K.J., Reppas C. (2019) Usefulness of Small-Scale Biphasic Dissolution Experiments in Estimating Precipitation Rates for Input in PBPK Modelling AAPS Annual Meeting [Details]
(2018)AAPS Annual Meeting
O’Dwyer P.J., Box K.J., Reppas C. (2018) Small Scale Biphasic Dissolution Testing of Itraconazole (ITZ) Formulations with a pH Shift AAPS Annual Meeting [Details]
(2017)AAPS Annual Meeting
O’Dwyer P.J., Box K.J., Watson H., Taylor R. (2017) In Vitro Modelling of Propranolol Immediate Release (IR) and Extended Release (ER) Formulations using a Three Chamber Dissolution Apparatus AAPS Annual Meeting [Details]
(2017)IAPC-6 Meeting
O’Dwyer P.J., Comer J., Taylor R., Box K.J. (2017) Small Scale Biphasic Dissolution testing of Dipyridamole Suspension IAPC-6 Meeting [Details]
(2017)AAPS Annual Meeting
Watson H., Box K.J., O'Dwyer P.J., Gehris A. (2017) Understanding Drug Release Mechanisms of Metformin using complementary in vitro Dissolution Tools AAPS Annual Meeting [Details]

Professional Activities

Honours and Awards

 YearTitleAwarding Body
2015Abbvie Prize for excellence in Pharmaceutics UCC School of Pharmacy
2015Dr. H.H. Stewart Medical Scholarship and Prize in Pharmacy National University of Ireland
2015School of Pharmacy Medal UCC School of Pharmacy

Professional Associations

 AssociationFunctionFrom / To
Pharmaceutical Society of Ireland Member30-NOV-16 /

Education

 YearInstitutionQualificationSubject
2015University College Cork BPharmPharmacy
2016Royal College of Surgeons in Ireland MPharmPharmacy
2020National and Kapodistrian University of Athens PhDPharmaceutics

Contact details

Search profiles by name

Search profiles by topic

School of Pharmacy

Cógaisíocht

Cavanagh Pharmacy Building Room UG06 University College Cork

Top