Research Profile

Patrick Gerard Casey

Biography

Biological Safety Advisor with the OVPRI, assisting  all users of biological agents and genetically modified organisms within the University operate according to relevant national and European legislation.

Research Interests

Preclinical models.

Probiotics.

Prebiotics.

Pathogens.

Infection.

Research Grants

 ProjectFunding
Body
Start DateEnd DateAward
SFI Research Infrastructure 2015 (Category D: Opportunistic Funding); Sub-project of R17475; 16/RI/3404Science Foundation of Ireland01-JAN-1730-JUN-19€132,840.00
UCC"Strategic Research Fund PhD 2014"P Casey [X]Miscellaneous30-SEP-1430-SEP-15€1,000.00

Publications

Peer Reviewed Journals

 YearPublication
(2019)'Lactobacillus gasseri APC 678 Reduces Shedding of the Pathogen Clostridium difficile in a Murine Model'
Quigley, L;Coakley, M;Alemayehu, D;Rea, MC;Casey, PG;O'Sullivan, O;Murphy, E;Kiely, B;Cotter, PD;Hill, C;Ross, RP (2019) 'Lactobacillus gasseri APC 678 Reduces Shedding of the Pathogen Clostridium difficile in a Murine Model'. Frontiers In Microbiology, 10 [DOI] [Details]
(2019)'Short-term consumption of a high-fat diet increases host susceptibility to Listeria monocytogenes infection'
Heras VL;Clooney AG;Ryan FJ;Cabrera-Rubio R;Casey PG;Hueston CM;Pinheiro J;Rudkin JK;Melgar S;Cotter PD;Hill C;Gahan CGM; (2019) 'Short-term consumption of a high-fat diet increases host susceptibility to Listeria monocytogenes infection'. Microbiome, 7 (1) [DOI] [Details]
(2018)'A Bifidobacterial pilus-associated protein promotes colonic epithelial proliferation'
O'Connell Motherway M, Houston A, O'Callaghan G, Reunanen J, O'Brien F, O'Driscoll T, Casey PG, de Vos WM, van Sinderen D, Shanahan F (2018) 'A Bifidobacterial pilus-associated protein promotes colonic epithelial proliferation'. Molecular Microbiology, [DOI] [Details]
(2018)'Carbohydrate Syntrophy enhances the establishment of Bifidobacterium breve UCC2003 in the neonatal gut'
Motherway, MO;O'Brien, F;O'Driscoll, T;Casey, PG;Shanahan, F;van Sinderen, D (2018) 'Carbohydrate Syntrophy enhances the establishment of Bifidobacterium breve UCC2003 in the neonatal gut'. Scientific Reports, 8 [DOI] [Details]
(2018)'Staying alive: growth and survival of Bifidobacterium animalis subsp. animalis under in vitro and in vivo conditions'
Egan M;Bottacini F;O'Connell Motherway M;Casey PG;Morrissey R;Melgar S;Faurie JM;Chervaux C;Smokvina T;van Sinderen D; (2018) 'Staying alive: growth and survival of Bifidobacterium animalis subsp. animalis under in vitro and in vivo conditions'. Applied Microbiology and Biotechnology, 102 (24) [DOI] [Details]
(2017)'A long and abundant non-coding RNA in Lactobacillus salivarius'
Cousin FJ, Lynch DB, Chuat V, Bourin MJB, Casey PG, Dalmasso M, Harris HMB, McCann A, O'Toole PW. (2017) 'A long and abundant non-coding RNA in Lactobacillus salivarius'. Microbial Glycobiology: Structures, Relevance And Applications, [Details]
(2017)'Development of a click beetle luciferase reporter system for enhanced bioluminescence imaging of Listeria monocytogenes: analysis in cell culture and murine infection models'
Ur Rahman S, Stanton M, Casey PG, Spagnuolo A, Bensi G, Hill C, Francis KP, Tangney M, Gahan CGM. (2017) 'Development of a click beetle luciferase reporter system for enhanced bioluminescence imaging of Listeria monocytogenes: analysis in cell culture and murine infection models'. Frontiers In Microbiology, [CORA Link] [Details]
(2017)'Genome-Wide Search for Genes Required for Bifidobacterial Growth under Iron-Limitation'
Lanigan N, Bottacini F, Casey PG, O'Connell Motherway M, van Sinderen D. (2017) 'Genome-Wide Search for Genes Required for Bifidobacterial Growth under Iron-Limitation'. Frontiers In Microbiology, [Details]
(2017)'The influence of rosuvastatin upon the gastrointestinal microbiota and host gene expression profiles'
Nolan JA, Skuse PH, Govindarajan K, Patterson E, Konstantinidou N, Casey PG, MacSharry J, Shanahan F, Stanton C, Hill C, Cotter PD, Joyce SA, Gahan CG (2017) 'The influence of rosuvastatin upon the gastrointestinal microbiota and host gene expression profiles'. American Journal Of Physiology-Gastrointestinal And Liver Physiology, [Details]
(2016)'Unconjugated Bile Acids Influence Expression of Circadian Genes: A Potential Mechanism for Microbe-Host Crosstalk'
Govindarajan K, MacSharry J, Casey PG, Shanahan F, Joyce SA, Gahan CG (2016) 'Unconjugated Bile Acids Influence Expression of Circadian Genes: A Potential Mechanism for Microbe-Host Crosstalk'. Plos One, 11 (12) [Details]
(2016)'Listeria monocytogenes mutants defective in gallbladder replication represent safety-enhanced vaccine delivery platforms'
Dowd GC, Bahey-el-Din M, Casey PG, Joyce SA, Hill C, Gahan CGM (2016) 'Listeria monocytogenes mutants defective in gallbladder replication represent safety-enhanced vaccine delivery platforms'. Human Vaccines & Immunotherapeutics, [DOI] [Details]
(2014)'Regulation of host weight gain and lipid metabolism by bacterial bile acid modification in the gut'
Joyce SA; MacSharry J; Casey PG; Kinsella M; Murphy EF; Shanahan F; Hill C; Gahan CG (2014) 'Regulation of host weight gain and lipid metabolism by bacterial bile acid modification in the gut'. Proceedings of The National Acadamy of Sciences, [Details]
(2014)'Exopolysaccharide-Producing Probiotic Lactobacilli Reduced Serum Cholesterol and Modified Enteric Microbiota in ApoE-Deficient Mice'
London LE, Kumar AH, Wall R, Casey PG, O'Sullivan O, Shanahan F, Hill C, Cotter PD, Fitzgerald GF, Ross RP, Caplice NM, Stanton C (2014) 'Exopolysaccharide-Producing Probiotic Lactobacilli Reduced Serum Cholesterol and Modified Enteric Microbiota in ApoE-Deficient Mice'. The Journal of Nutrition, [DOI] [Details]
(2014)'Divergent Evolution of the Activity and Regulation of the Glutamate Decarboxylase Systems in Listeria monocytogenes EGD-e and 10403S: Roles in Virulence and Acid Tolerance'
Feehily C, Finnerty A, Casey PG, Hill C, Gahan CG, O'Byrne CP, Karatzas KA (2014) 'Divergent Evolution of the Activity and Regulation of the Glutamate Decarboxylase Systems in Listeria monocytogenes EGD-e and 10403S: Roles in Virulence and Acid Tolerance'. Plos One, 9 (11) [DOI] [Details]
(2014)'Autoinducer-2 Plays a Crucial Role in Gut Colonization and Probiotic Functionality of Bifidobacterium breve UCC2003'
Christiaen SE; O'Connell Motherway M; Bottacini F; Lanigan N; Casey PG; Huys G; Nelis HJ; van Sinderen D; Coenye T (2014) 'Autoinducer-2 Plays a Crucial Role in Gut Colonization and Probiotic Functionality of Bifidobacterium breve UCC2003'. Plos One, [Details]
(2014)'Bioavailability of the anti-clostridial bacteriocin thuricin CD in gastrointestinal tract'
Rea MC; Alemayehu D; Casey PG; O'Connor PM; Lawlor PG; Walsh M; Shanahan F; Kiely B; Ross RP; Hill C (2014) 'Bioavailability of the anti-clostridial bacteriocin thuricin CD in gastrointestinal tract'. Microbiology, [Details]
(2014)'Two-tiered biological containment strategy for Lactococcus lactis-based vaccine or immunotherapy vectors'
Hanin A; Culligan EP; Casey PG; Bahey-El-Din M; Hill C; Gahan CG (2014) 'Two-tiered biological containment strategy for Lactococcus lactis-based vaccine or immunotherapy vectors'. Human Vaccines & Immunotherapeutics, [Details]
(2014)'MyD88 adaptor-like (Mal) functions in the epithelial barrier and contributes to intestinal integrity via protein kinase C'
Corr SC; Palsson-McDermott EM; Grishina I; Barry SP; Aviello G; Bernard NJ; Casey PG; Ward JB; Keely SJ; Dandekar S; Fallon PG; O'Neill LA (2014) 'MyD88 adaptor-like (Mal) functions in the epithelial barrier and contributes to intestinal integrity via protein kinase C'. Mucosal immunology, [Details]
(2013)'A mariner transposon-based signature-tagged mutagenesis system for the analysis of oral infection by Listeria monocytogenes'
Cummins J; Casey PG; Joyce SA; Gahan CG (2013) 'A mariner transposon-based signature-tagged mutagenesis system for the analysis of oral infection by Listeria monocytogenes'. Plos One, [Details]
(2013)'In vivo activity of nisin A and nisin V against Listeria monocytogenes in mice'
Campion A; Casey PG; Field D; Cotter PD; Hill C; Ross RP (2013) 'In vivo activity of nisin A and nisin V against Listeria monocytogenes in mice'. BMC Microbiology, [Details]
(2013)'In vivo assessment of growth and virulence gene expression during commensal and pathogenic lifestyles of luxABCDE-tagged Enterococcus faecalis strains in murine gastrointestinal and intravenous infection models'
Leanti La Rosa S; Casey PG; Hill C; Diep DB; Nes IF; Brede DA (2013) 'In vivo assessment of growth and virulence gene expression during commensal and pathogenic lifestyles of luxABCDE-tagged Enterococcus faecalis strains in murine gastrointestinal and intravenous infection models'. Applied and Environmental Microbiology, [Details]
(2013)'Virulence aspects of Listeria monocytogenes LO28 high pressure-resistant variants'
Van Boeijen IK; Casey PG; Hill C; Moezelaar R; Zwietering MH; Gahan CG; Abee T (2013) 'Virulence aspects of Listeria monocytogenes LO28 high pressure-resistant variants'. Microbial Pathogenesis, [Details]
(2013)'A mutant in the Listeria monocytogenes Fur-regulated virulence locus (frvA) induces cellular immunity and confers protection against listeriosis in mice'
McLaughlin HP; Bahey-El-Din M; Casey PG; Hill C; Gahan CG (2013) 'A mutant in the Listeria monocytogenes Fur-regulated virulence locus (frvA) induces cellular immunity and confers protection against listeriosis in mice'. Journal of Medical Microbiology, [Details]
(2012)'Investigation of the role of ZurR in the physiology and pathogenesis of Listeria monocytogenes'
Dowd, G.C. and Casey, P.G. and Begley, M. and Hill, C. and Gahan, C.G.M. (2012) 'Investigation of the role of ZurR in the physiology and pathogenesis of Listeria monocytogenes'. Fems Microbiology Letters, [Details]
(2012)'The Lantibiotic Lacticin 3147 Prevents Systemic Spread of Staphylococcus aureus in a Murine Infection Model'
Piper, C. and Casey, P.G. and Hill, C. and Cotter, P.D. and Ross, R.P. (2012) 'The Lantibiotic Lacticin 3147 Prevents Systemic Spread of Staphylococcus aureus in a Murine Infection Model'. International Journal of Microbiology, 2012 [Details]
(2012)'Bacteriophages phi MR299-2 and phi NH-4 Can Eliminate Pseudomonas aeruginosa in the Murine Lung and on Cystic Fibrosis Lung Airway Cells'
Alemayehu, D.,Casey, P. G.,McAuliffe, O.,Guinane, C. M.,Martin, J. G.,Shanahan, F.,Coffey, A.,Ross, R. P.,Hill, C. (2012) 'Bacteriophages phi MR299-2 and phi NH-4 Can Eliminate Pseudomonas aeruginosa in the Murine Lung and on Cystic Fibrosis Lung Airway Cells'. MBio, 3 (22)   [Details]
(2012)'Effect of Lactobacillus salivarius bacteriocin Abp118 on the mouse and pig intestinal microbiota'
Riboulet-Bisson E; Sturme MH; Jeffery IB; O'Donnell MM; Neville BA; Forde BM; Claesson MJ; Harris H; Gardiner GE; Casey PG; Lawlor PG; O'Toole PW; Ross RP (2012) 'Effect of Lactobacillus salivarius bacteriocin Abp118 on the mouse and pig intestinal microbiota'. Plos One, [Details]
(2012)'A novel host-responsive sensor mediates virulence and type III secretion during Pseudomonas aeruginosa-host cell interactions'
O'Callaghan J; Reen FJ; Adams C; Casey PG; Gahan CG; O'Gara F (2012) 'A novel host-responsive sensor mediates virulence and type III secretion during Pseudomonas aeruginosa-host cell interactions'. Microbiology, [Details]
(2012)'A putative P-type ATPase required for virulence and resistance to haem toxicity in Listeria monocytogenes'
McLaughlin HP; Xiao Q; Rea RB; Pi H; Casey PG; Darby T; Charbit A; Sleator RD; Joyce SA; Cowart RE; Hill C; Klebba PE; Gahan CG (2012) 'A putative P-type ATPase required for virulence and resistance to haem toxicity in Listeria monocytogenes'. Plos One, [Details]
(2012)'HmgR, a key enzyme in the mevalonate pathway for isoprenoid biosynthesis, is essential for growth of Listeria monocytogenes EGDe'
Heuston S; Begley M; Davey MS; Eberl M; Casey PG; Hill C; Gahan CG (2012) 'HmgR, a key enzyme in the mevalonate pathway for isoprenoid biosynthesis, is essential for growth of Listeria monocytogenes EGDe'. Microbiology, [Details]
(2012)'H5N1 moratorium: Missing the point'
Casey, PG (2012) 'H5N1 moratorium: Missing the point'. Bioengineered Bugs, [Details]
(2012)'Residual antibiotics disrupt meat fermentation and increase risk of infection'
Kjeldgaard J; Cohn MT; Casey PG; Hill C; Ingmer H (2012) 'Residual antibiotics disrupt meat fermentation and increase risk of infection'. Mbio, [Details]
(2011)'Fate and efficacy of lacticin 3147-producing Lactococcus lactis in the mammalian gastrointestinal tract'
Dobson, A. and Crispie, F. and Rea, M.C. and O'Sullivan, O. and Casey, P.G. and Lawlor, P.G. and Cotter, P.D. and Ross, P. and Gardiner, G.E. and Hill, C. (2011) 'Fate and efficacy of lacticin 3147-producing Lactococcus lactis in the mammalian gastrointestinal tract'. FEMS microbiology ecology, [Details]
(2011)'Functional genome analysis of Bifidobacterium breve UCC2003 reveals type IVb tight adherence (Tad) pili as an essential and conserved host-colonization factor'
Motherway, M. O.,Zomer, A.,Leahy, S. C.,Reunanen, J.,Bottacini, F.,Claesson, M. J.,O'Brien, F.,Flynn, K.,Casey, P. G.,Munoz, J. A. M.,Kearney, B.,Houston, A. M.,O'Mahony, C.,Higgins, D. G.,Shanahan, F.,Palva, A.,de Vos, W. M.,Fitzgerald, G. F.,Ventura, M.,O'Toole, P. W.,van Sinderen, D. (2011) 'Functional genome analysis of Bifidobacterium breve UCC2003 reveals type IVb tight adherence (Tad) pili as an essential and conserved host-colonization factor'. Proc Natl Acad Sci U S Aproc Natl Acad Sci U S A, 108 (2727):11217-11222   [Details]
(2011)'E. coli O104: H4: Social media and the characterisation of an emerging pathogen'
Casey, P.G. and Hill, C. and Gahan, CG (2011) 'E. coli O104: H4: Social media and the characterisation of an emerging pathogen'. Bioengineered bugs, 2 (4) [Details]
(2011)'Factors affecting survival of Listeria monocytogenes and Listeria innocua in soil samples'
McLaughlin, H.P. and Casey, P.G. and Cotter, J. and Gahan, C.G.M. and Hill, C. (2011) 'Factors affecting survival of Listeria monocytogenes and Listeria innocua in soil samples'. Archives of Microbiology, :1-11 [Details]
(2010)'Use of bioluminescence imaging to track neutrophil migration and its inhibition in experimental colitis'
Murphy, CT;Moloney, G;Hall, LJ;Quinlan, A;Faivre, E;Casey, P;Shanahan, F;Melgar, S;Nally, K (2010) 'Use of bioluminescence imaging to track neutrophil migration and its inhibition in experimental colitis'. Clinical and Experimental Immunology, 162 :188-196 [DOI] [Details]
(2010)'Expression of two Listeria monocytogenes antigens (P60 and LLO) in Lactococcus lactis and examination for use as live vaccine vectors'
Bahey-El-Din M, Casey PG, Griffin BT, Gahan CG (2010) 'Expression of two Listeria monocytogenes antigens (P60 and LLO) in Lactococcus lactis and examination for use as live vaccine vectors'. Journal of Medical Microbiology, [Details]
(2010)'The truncated phage lysin CHAP(k) eliminates Staphylococcus aureus in the nares of mice'
Fenton M, Casey PG, Hill C, Gahan CG, Ross RP, McAuliffe O, O'Mahony J, Maher F, Coffey A (2010) 'The truncated phage lysin CHAP(k) eliminates Staphylococcus aureus in the nares of mice'. Bioengineered Bugs, [Details]
(2010)'Directed evolution and targeted mutagenesis to murinize Listeria monocytogenes internalin A for enhanced infectivity in the murine oral infection model'
Monk IR, Casey PG, Hill C, Gahan CG (2010) 'Directed evolution and targeted mutagenesis to murinize Listeria monocytogenes internalin A for enhanced infectivity in the murine oral infection model'. BMC Microbiology, [Details]
(2010)'Efficacy of a Lactococcus lactis ΔpyrG vaccine delivery platform expressing chromosomally integrated hly from Listeria monocytogenes'
Bahey-EL-Din, M; Caset, PG; Griffin, BT; Gahan, C; (2010) 'Efficacy of a Lactococcus lactis ΔpyrG vaccine delivery platform expressing chromosomally integrated hly from Listeria monocytogenes'. Bioengineered Bugs, 1 (1):66-74   [Details]
(2009)'Allelic variation of bile salt hydrolase genes in Lactobacillus salivarius does not determine bile resistance levels'
Fang F, Li Y, Bumann M, Raftis EJ, Casey PG, Cooney JC, Walsh MA, O'Toole PW (2009) 'Allelic variation of bile salt hydrolase genes in Lactobacillus salivarius does not determine bile resistance levels'. Journal of Bacteriology, [Details]
(2009)'Evaluation of colostrum-derived human mammary-associated serum amyloid A3 (M-SAA3) protein and peptide derivatives for the prevention of enteric infection: in vitro and in murine models of intestinal disease'
Gardiner, G. E.,O'Flaherty, S.,Casey, P. G.,Weber, A.,McDonald, T. L.,Cronin, M.,Hill, C.,Ross, R. P.,Gahan, C. G. M.,Shanahan, F. (2009) 'Evaluation of colostrum-derived human mammary-associated serum amyloid A3 (M-SAA3) protein and peptide derivatives for the prevention of enteric infection: in vitro and in murine models of intestinal disease'. Fems Immunology and Medical Microbiology, 55 (33):404-413404   [Details]
(2009)'Specific osmolyte transporters mediate bile tolerance in Listeria monocytogenes'
Watson D, Sleator RD, Casey PG, Hill C, Gahan CG (2009) 'Specific osmolyte transporters mediate bile tolerance in Listeria monocytogenes'. Infection and Immunity, [Details]
(2009)'AgrD-dependent quorum sensing affects biofilm formation, invasion, virulence and global gene expression profiles in Listeria monocytogenes'
Riedel CU, Monk IR, Casey PG, Waidmann MS, Gahan CG, Hill C (2009) 'AgrD-dependent quorum sensing affects biofilm formation, invasion, virulence and global gene expression profiles in Listeria monocytogenes'. Molecular Microbiology, [Details]
(2008)'Listeriolysin S, a novel peptide haemolysin associated with a subset of lineage I Listeria monocytogenes'
Cotter, P.D. and Draper, L.A. and Lawton, E.M. and Daly, K.M. and Groeger, D.S. and Casey, P.G. and Ross, R.P. and Hill, C. (2008) 'Listeriolysin S, a novel peptide haemolysin associated with a subset of lineage I Listeria monocytogenes'. PLoS pathogens, 4 (9) [CORA Link] [Details]
(2008)'Pseudomonas aeruginosa RsmA plays an important role during murine infection by influencing colonization, virulence, persistence, and pulmonary inflammation'
Mulcahy, H., O'Callaghan, J., O'Grady, E.P., Macia, M.D., Borrell, N., Gomez, C., Casey, P.G., Hill, C., Adams, C., Gahan, C.G.M., Oliver, A., and O'Gara, F.; (2008) 'Pseudomonas aeruginosa RsmA plays an important role during murine infection by influencing colonization, virulence, persistence, and pulmonary inflammation'. Infection and Immunity, 76 (2):632-638 [DOI] [Details]
(2008)'Development of multiple strain competitive index assays for Listeria monocytogenes using pIMC; a new site-specific integrative vector'
Monk IR, Casey PG, Cronin M, Gahan CG, Hill C (2008) 'Development of multiple strain competitive index assays for Listeria monocytogenes using pIMC; a new site-specific integrative vector'. BMC Microbiology, 8: 96 [DOI] [CORA Link] [Details]
(2008)'Lactococcus lactis-expressing listeriolysin O (LLO) provides protection and specific CD8(+) T cells against Listeria monocytogenes in the murine infection model'
Bahey-El-Din M, Casey PG, Griffin BT, Gahan CG; (2008) 'Lactococcus lactis-expressing listeriolysin O (LLO) provides protection and specific CD8(+) T cells against Listeria monocytogenes in the murine infection model'. Vaccine, 26 (41):5304-5314 [DOI] [Details]
(2008)'Analysis of the isoprenoid biosynthesis pathways in Listeria monocytogenes reveals a role for the alternative 2-C-methyl-D-erythritol 4-phosphate pathway in murine infection'
Begley M, Bron PA, Heuston S, Casey PG, Englert N, Wiesner J, Jomaa H, Gahan CG, Hill C (2008) 'Analysis of the isoprenoid biosynthesis pathways in Listeria monocytogenes reveals a role for the alternative 2-C-methyl-D-erythritol 4-phosphate pathway in murine infection'. Infection and Immunity, [Details]
(2007)'Improved luciferase tagging system for Listeria monocytogenes allows real-time monitoring in vivo and in vitro'
Riedel, C. U.,Monk, I. R.,Casey, P. G.,Morrissey, D.,O'Sullivan, G. C.,Tangney, M.,Hill, C.,Gahan, C. G.; (2007) 'Improved luciferase tagging system for Listeria monocytogenes allows real-time monitoring in vivo and in vitro'. Applied and Environmental Microbiology, 73 (99):3091-43091   [Details]
(2007)'Construction of p16Slux, a novel vector for improved bioluminescent labeling of gram-negative bacteria'
Riedel, C.U. and Casey, P.G. and Mulcahy, H. and O'Gara, F. and Gahan, C.G.M. and Hill, C. (2007) 'Construction of p16Slux, a novel vector for improved bioluminescent labeling of gram-negative bacteria'. Applied and environmental microbiology, 73 (21):7092-7095 [Details]
(2007)'A five-strain probiotic combination reduces pathogen shedding and alleviates disease signs in pigs challenged with Salmonella enterica serovar Typhimurium'
Casey, P.G. and Gardiner, G.E. and Casey, G. and Bradshaw, B. and Lawlor, P.G. and Lynch, P.B. and Leonard, F.C. and Stanton, C. and Ross, R.P. and Fitzgerald, G.F. and others (2007) 'A five-strain probiotic combination reduces pathogen shedding and alleviates disease signs in pigs challenged with Salmonella enterica serovar Typhimurium'. Applied and environmental microbiology, 73 (6) [Details]
(2004)'Isolation and characterization of anti-Salmonella lactic acid bacteria from the porcine gastrointestinal tract'
Casey, P. G.,Casey, G. D.,Gardiner, G. E.,Tangney, M.,Stanton, C.,Ross, R. P.,Hill, C.,Fitzgerald, G. F.; (2004) 'Isolation and characterization of anti-Salmonella lactic acid bacteria from the porcine gastrointestinal tract'. Letters of Applied Microbiology, 39 (55):431-8431   [Details]
(2004)'Relative ability of orally administered Lactobacillus murinus to predominate and persist in the porcine gastrointestinal tract'
Gardiner, G.E. and Casey, P.G. and Casey, G. and Lynch, P.B. and Lawlor, P.G. and Hill, C. and Fitzgerald, G.F. and Stanton, C. and Ross, R.P. (2004) 'Relative ability of orally administered Lactobacillus murinus to predominate and persist in the porcine gastrointestinal tract'. Applied and environmental microbiology, 70 (4) [Details]
(2004)'Salmonella carriage in an Irish pig herd: correlation between serological and bacteriological detection methods'
Casey, P. G.,Butler, D.,Gardiner, G. E.,Tangney, M.,Simpson, P.,Lawlor, P. G.,Stanton, C.,Ross, R. P.,Hill, C.,Fitzgerald, G. F.; (2004) 'Salmonella carriage in an Irish pig herd: correlation between serological and bacteriological detection methods'. Journal of Food Protection, 67 (1212):2797-8002797   [Details]
(2002)'Sodium chloride decreases the bacteriocidal effect of acid pH on Escherichia coli O157 : H45'
Casey, PG,Condon, S; (2002) 'Sodium chloride decreases the bacteriocidal effect of acid pH on Escherichia coli O157 : H45'. International Journal of Food Microbiology, 76 :199-206 [DOI] [Details]

Conference Publications

 YearPublication
(2007)Pseudomonas 2007 (ASM Conference)
O'Callaghan, J and Mulcahy, H and Casey, Pg and Baysse, Christine and O'grady, EP and Hill, C and Adams, C and Gahan, Cg and O'gara, F and others (2007) Comparative analysis of Pseudomonas aeruginosa strains, altered in their ability to cause acute infection, in response to bronchial epithelial cells Pseudomonas 2007 (ASM Conference) [Details]
(2000)INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY
Casey, P;Condon, S (2000) Synergistic lethal combination of nitrite and acid pH on a verotoxin-negative strain of Escherichia coli O157 INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY , pp.255-258 [Details]

Conference Paper

 YearPublication
(2007)Role of Agrd For Biofim Formation and Virulence In L. Monocytogenes.
Riedel, CU, Monk, IR, Casey, P, Gahan, CGM, Hill, C; (2007) Role of Agrd For Biofim Formation and Virulence In L. Monocytogenes. Conference Paper [Details]

Professional Activities

Education

 YearInstitutionQualificationSubject
2015Animal Care & Welfare Officer CertificateACWO course
2014Institute of Safety in Technology and Research CertificateBiosafety
2011Institute of Animal Technology National Certificate in BiologyAnimal Technology
2009American Association for Laboratory Animal Science CertificateLaboratory Animal Technician
2007Institute of Animal Technology CertificateAnimal Technology
2001University College Cork M.Sc.Microbiology
1997University College Cork B.Sc. (Honours)Microbiology

Committees

 CommitteeFunctionFrom / To
European Biosafety Association Council Council Member2019 / 2021
Animal Welfare Body review panel Welfare review of projects2018 /
Animal Experimentation Ethics Committee Biosafety Advisor2017 /
Genetic Engineering Advisory Group Compliance Officer2010 /
Biological Safety Advisory Group APC representative2014 /

Honours and Awards

 YearTitleAwarding Body
2018Attendance grant to EBSA conference European Biosafety Association
2017SFI Infrastructure Award SFI
2016Winner - Irish Lab Awards Staff Member of the Year Irish Laboratory Awards
2014UCC Research Support Person of the Year University College Cork
2007Marie Curie Attendance Award Marie Curie
2007Attendance grant European Society for Clinical Microbiology and Infectious Diseases
2014Irish Lab Awards Staff Member of the Year Finalist Irish Laboratory Awards

Outreach Activities

 Description

Judge, Debating Science Issues (schools science debating competition). 2010 - present.

Schools presentations, APC outreach programme. 2004 - present.

Outreach assistant, APC display at Science Week installation in Cork City Hall. 2005 - 2010.

Professional Associations

 AssociationFunctionFrom / To
Institute of Safety in Technology and Research Registered Biosafety Practitioner/
European Biosafety Association Member/
Institute of Animal Technology Member/
American Association for Laboratory Animal Science Member/
European Society of Clinical Microbiology and Infectious Diseases Member/
British Infection Society Member/
Society for General Microbiology Member/

Journal Activities

 JournalRoleTo / From
Bioengineered Member of Editorial Board-
Journal Of Medical Microbiology Referee-
Virulence Referee-
Molecular Microbiology Referee-
Gut Pathogens Referee-

Other Activities

 Description

European Biosafety Association conference, Bucharest, April 2019

Inaugural Irish Biosafety Network meeting, Dublin Oct 2018

Institute of Animal Technology Irish Branch Symposium, May 2018

European Biosafety Association conference, Copenhagen - presenter, April 2018

New Horizons conference, School of Medicine, UCC - speaker, December 2017

Institute of Animal Technology Irish Branch symposium (speaker) - Dublin, May 2017.

Vision2020 RTO members' workshop - Cork, May 2017.

HPRA / SFI / HRB 3Rs conference - Dublin, May 2017.

NC3Rs workshop: "Accelerating the acceptance of mathematical models", London, September 2016.

SynBio Future 2016: Future Axioms in Synthetic Biology, February 2016.

Perkin Elmer IVIS Users' workshop, Imperial College London, July 2015.

Biosafety Masterclass, Cambridge January 2015.

Invited seminar, Irish Cytometry Society annual meeting, Dublin, February 2014.

Conference Contributions

 YearPublication
(2007)Pseudomonas 2007,
O'callaghan, J. and Mulcahy, H. and Casey, P. and Baysse, C. and O'grady, EP and Hill, C. and Adams, C. and Gahan, C. and O'gara, F. (2007) Comparative analysis of Pseudomonas aeruginosa strains, altered in their ability to cause acute infection, in response to bronchial epithelial cells. [N/A], Pseudomonas 2007, Seattle . [Details]

Languages

 LanguageReadingWritingSpeaking
Russian BasicBasicBasic
Irish FunctionalFunctionalFunctional
German FunctionalBasicBasic
French FunctionalFunctionalBasic

Research Information

External Collaborators

 NameOrganisation / InstituteCountry
Tjakko Abee Wageningen University and Research CentreHOLLAND
Catherine Stanton TeagascIRELAND
Sabina Leanti La Rosa Norwegian University of Life SciencesNORWAY
Eileen Murphy Alimentary HealthIRELAND
Hanne Ingmer University of CopenhagenDENMARK
Paul Ross TeagascIRELAND
Dag A Brede Norwegian University of Life SciencesNORWAY
Sinead Corr Trinity College DublinIRELAND
Conor O'Byrne National University of Ireland, GalwayIRELAND
Paul Cotter TeagascIRELAND
Steven Christiaen Ghent UniversityBELGIUM
Mary Rea TeagascIRELAND

Contact details

  • Patrick Gerard Casey
    Biological Safety Advisor
  • p.casey@ucc.ie
  • Office of the Vice President for Research and Innovation
    7 Bloomfield Terrace
    University College Cork
    Western Road, Cork
  • 021 4901443
  • 087 1901917

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