| F. M. Deane, E. C. O’Sullivan, A. R. Maguire, J. Gilbert, J. A. Sakoff, A. McCluskey and F. O. McCarthy (2013) 'Synthesis
and evaluation of novel Ellipticines as potential anti-cancer agents'. Organic and Biomolecular Chemistry, 11 (8):1334-1344. [DOI] [Details]
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| O'Callaghan Y, Kenny O, O'Connell NM, Maguire AR, McCarthy FO, O'Brien NM (2013) 'Synthesis and assessment of the relative
toxicity of the oxidised derivatives of campesterol and dihydrobrassicasterol in U937 and HepG2 cells'. Biochimie, 95 (3):496-503. [DOI] [Details]
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| L. T. Pierce, M. M. Cahill, H. J. Winfield and F. O. McCarthy (2012) 'Synthesis and identification of novel indolo[2,3-a]pyrimido[5,4-c]carbazoles
as a new class of anti-cancer agents'. European Journal of Medicinal Chemistry, 56 :292-300. [DOI] [Details]
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| C. M. Miller, E. C. O’Sullivan, K. J. Devine and F. O. McCarthy (2012) 'Synthesis and Biological Evaluation of Novel Isoellipticine
Derivatives and Salts'. Organic and Biomolecular Chemistry, 10 (39):7912-7921. [DOI] [Details]
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| O. Kenny, Y. O'Callaghan, N. M. O'Connell, F. O. McCarthy, A. R. Maguire and N. M. O'Brien (2012) 'Oxidised Derivatives of
Dihydrobrassicasterol: Cytotoxic and Apoptotic Potential in U937 and HepG2 cells'. Journal of Agricultural and Food Chemistry, 60 (23):5952-5961. [DOI] [Details]
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| C. M. Miller and F. O. McCarthy (2012) 'Isolation, biological activity and synthesis of the natural product ellipticine and
related pyridocarbazoles'. RSC Advances, 2 (24):8883-8918. [DOI] [Details]
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| N. M. O’Connell, Y. C. O’Callaghan, N. M. O’Brien, A. R. Maguire and F. O. McCarthy (2012) 'Synthetic routes to Campesterol
and Dihydrobrassicasterol: a first reported synthesis of the key phytosterol Dihydrobrassicasterol'. Tetrahedron, 68 (25):4995-5004. [DOI] [Details]
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F.O. McCarthy (2012) 'Is LCMS fast becoming an essential technique for pharmaceuticals'. European Pharmaceutical Review, 17 (1):54-59.  [Details]
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| L. T. Pierce, M. M. Cahill and F. O. McCarthy (2011) 'Synthesis of novel 3,4-diaryl-5-aminopyrazoles as potential kinase inhibitors'.
Tetrahedron, 67 (25):4601-4611. [DOI] [Details]
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| Deane, FM; Miller, CM; Maguire, AR; McCarthy, FO; (2011) 'Modifications to the Vilsmeier-Haack formylation of 1,4-dimethylcarbazole
and its application to the synthesis of ellipticines'. Journal of Heterocyclic Chemistry, 48 (4):814-823. [DOI] [Details]
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| L. T. Pierce, M. M. Cahill and F. O. McCarthy; (2010) 'Design And Synthesis Of Novel 5,6-Bisindolylpyrimidin-4-Ones Structurally
Related To Ruboxistaurin (LY333531)'. Tetrahedron, 66 (51):9754-9761. [DOI] [Details]
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| O'Callaghan, YC; Foley, DA; O'Connell, NM; McCarthy, FO; Maguire, AR; O'Brien, NM; (2010) 'Cytotoxic and Apoptotic Effects
of the Oxidized Derivatives of Stigmasterol in the U937 Human Monocytic Cell Line'. Journal of Agricultural and Food Chemistry, 58 (19):10793-10798. [Details]
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| Foley, DA; O'Callaghan, Y; O'Brien, NM; McCarthy, FO; Maguire, AR; (2010) 'Synthesis and characterisation of stigmasterol
oxidation products'. Journal of Agricultural and Food Chemistry, 58 :1165-1173. [Details]
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| E. Ryan, F. O. McCarthy, A. R. Maguire and N. M. O'Brien. ; (2009) 'Phytosterol Oxidation Products: Their Formation, Occurrence,
and Biological Effects'. Food Reviews International, 25 :157-174. [Details]
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| Pierce, Larry T; Cahill, Michael M; McCarthy, Florence O; (2009) 'Design and synthesis of novel indolocarbazole derivatives
as anti-cancer agents'. Drugs of the Future, 34 (Suppl A):100-100. [Details]
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| Miller, C; Thompson, D; McCarthy, FO; (2009) 'Design and synthesis of novel ellipticine c-Kit Kinase inhibitors'. Drugs of the Future, 34 (Suppl A):102-102. [Details]
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| D. Thompson, C. Miller, F.O. McCarthy; (2008) 'Computer Simulations Reveal a Novel Nucleotide-type Binding Orientation for
Ellipticine-based Anticancer c-kit Kinase Inhibitors'. Biochemistry, 47 :10333-10344. [Details]
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| R. L. Clark, F. M. Deane, N. G. Anthony, B. F. Johnston, F. O. McCarthy and S. P. Mackay. ; (2007) 'Exploring DNA topoisomerase
I inhibition by the benzo[c]phenanthridines fagaronine and ethoxidine using steered molecular dynamics'. Bioorganic and Medicinal Chemistry, 15 :4741-4752. [Details]
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| F. O. McCarthy, J. Chopra, A. Ford, S. A. Hogan, J. P. Kerry, N. O'Brien, E. Ryan and A. R. Maguire; (2005) 'Synthesis, isolation
and characterisation of β-sitosterol and β-sitosterol oxide derivatives'. Organic and Biomolecular Chemistry, 3 (16):3059-3065. [Details]
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| E. Ryan;J. Chopra;F. McCarthy;A. R. Maguire;N. M. O'Brien; (2005) 'Qualitative and quantitative comparison of the cytotoxic
and apoptotic potential of phytosterol oxidation products with their corresponding cholesterol oxidation products'. British Journal of Nutrition, 94 :443-451. [DOI] [Full Text] [Details]
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| Ryan, E., Chopra, J., McCarthy, F., Maguire, A.R. and O'Brien, N.M.; (2005) 'Qualitative and quantitative comparison of the
cytotoxic and apoptotic potential of phytosterol oxidation products with their corresponding cholesterol oxidation products'.
British Journal of Nutrition, 94 (*):443-451. [Details]
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| Ryan E., Galvin K., O’Connor T.P., McCarthy F.O., Maguire A.R. and O’Brien N.M.; (2005) 'Fatty acid profile, tocopherol, squalene
and phytosterol content of brazil, pecan, pine, pistachio and cashew nuts'. International Journal of Food Sciences and Nutrition, * (*):*-*. [Details]
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| Ryan E., Galvin K., O'Connor T.P., McCarthy F.O., Maguire A.R. and O'Brien N.M.; (2005) 'Phytosterol, tocopherol and squalene
content of five edible nuts (Brazil, Pecan, Pine, Pistachio, Cashew)'. Proceedings of The Nutrition Society, * (*):*-*. [Details]
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| F. O. McCarthy, D. Cairns, P. W. Groundwater and S. P. Mackay; (2002) 'Molecular modelling of novel ellipticine-amino acid
inhibitors of topoisomerase I'. J. Pharm. Pharmacol, 54(Suppl) . [Details]
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| D. Cairns, F.O. McCarthy, P.W. Groundwater and S.P. Mackay; (2000) 'The design of novel ellipticine-amino acid topoisomerase
I inhibitors'. Clinical Cancer Research, 6 . [Details]
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| W. Rhys-Williams, F. McCarthy, J. Baker, Y.F. Hung, M. Thomason, A. W. Lloyd and G. W. Hanlon; (1998) 'A mechanistic investigation
into the microbial chiral inversion of 2-arylpropionic acids using deuterated derivatives of 2-phenylpropionic acid'. Enzyme Microb. Technol, 22 (4):281-287. [Details]
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| Elaine C. O'Sullivan, Charlotte M. Miller, Ken Devine and Florence O. McCarthy. ; (2011) Synthesis and evaluation of novel
Ellipticine derivatives as anti-cancer agents XXth Conference of the Groupement des Pharmacochimistes de l'Arc Atlantique [Details]
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| Michael M. Cahill, Larry T. Pierce, Hannah J. Winfield, Florence O. McCarthy; (2011) Anticancer activity of novel azaindole
derivatives related to the bisindolemaleimides XXth Conference of the Groupement des Pharmacochimistes de l'Arc Atlantique [Details]
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| Hannah J. Winfield, Michael M. Cahill, Larry T. Pierce, Florence O. McCarthy; (2011) Synthesis of novel functionalised imidazoles
as potential anticancer agents XXth Conference of the Groupement des Pharmacochimistes de l'Arc Atlantique [Details]
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| Kieran Greaney and Florence O. McCarthy; (2011) Synthesis of Novel Quinoxalines as Potential HIV Integrase Inhibitors (Bio)Pharmaceutical and Pharmacological Sciences (BPS) Conference Dublin City University, Dublin, , 11-JAN-11 - 11-JAN-11 [Details]
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| Greaney, Kieran; McCarthy, Florence O; (2010) Synthesis of Novel Quinoxalines as Potential HIV Integrase Inhibitors XIXth European Conference of GP2A Groupement des Pharmacochimistes de l'Arc Atlantique Rouen, France, , 01-SEP-10 - 02-SEP-10 , pp.27-27 [Details]
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| Cahill, Michael M; Pierce, Larry T; Devine, Ken J; McCarthy, Florence O; (2010) Synthetic Studies towards Novel Azaindolocarbazoles
XIXth European Conference of GP2A Groupement des Pharmacochimistes de l'Arc Atlantique Rouen, France, , 01-SEP-10 - 02-SEP-10 , pp.36-36 [Details]
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| C. Miller, D. Thompson and F. O. McCarthy; (2009) Design and synthesis of novel ellipticine c-Kit kinase inhibitors XVIIIth European Conference of GP2A Groupement des Pharmacochimistes de l'Arc Atlantique Trinity College Dublin, Ireland, , 03-SEP-09 - 04-SEP-09 , pp.35-35 [Details]
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| L. T. Pierce, M. M. Cahill and F. O. McCarthy; (2009) Design and synthesis of novel indolocarbazole derivatives as anticancer
agents XVIIIth European Conference of GP2A Groupement des Pharmacochimistes de l'Arc Atlantique Trinity College Dublin, , 03-SEP-09 - 04-SEP-09 , pp.48-48 [Details]
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| Larry T. Pierce, Michael M. Cahill, Florence O. McCarthy ; (2008) Design, synthesis and development of novel indolocarbazole
derivatives as potential anti-cancer agents XVIIth European conference of GP2A Caen, France, , 28-MAY-08 - 30-MAY-08 [Details]
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| N. O' Connell, F. O. McCarthy, A. R. Maguire, N. O' Brien ; (2008) A novel route to individual phytosterols XVIIth European conference of GP2A Caen, France, , 28-MAY-08 - 30-MAY-08 [Details]
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| F.O. McCarthy; (2007) Novel Ellipticines in Cancer research XVIèmes Rencontres Europeennes du Groupment des Pharmacochimistes de L'Arc Atlantique (GP2A) Bordeaux, France, , 06-SEP-07 - 07-SEP-07 [Details]
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| F.O. McCarthy; (2006) Explaining the dual mechanism of DNA topoisomerase I inhibition by the benzo[c]phenanthridines fagaronine
and ethoxidine by molecular modeling XVth European conference of GP2A University of Bath, UK, , 07-SEP-06 - 08-SEP-06 [Details]
|
| F. M. Deane, F. O. McCarthy, A. R. Maguire, H. Major and S. Preece; (2006) Synthesis and evaluation of ellipticine derivatives
as potential anti-cancer agents XVth European conference of GP2A Bath, UK, , 07-SEP-06 - 08-SEP-06 [Details]
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| E. Ryan, K. Galvin, T.P. O'Connor, F.O. McCarthy, A. R. Maguire and N. M. O¿Brien; (2005) Phytosterol, tocopherol and squalene content of five edible nuts (Brazil, pecan, pine, pistachio, cashew) , pp.41-41 [Details]
|
| F.O. McCarthy, D. Cairns, P.W. Groundwater and S.P. Mackay; (2002) Molecular modelling of novel ellipticine-amino acid inhibitors
of topoisomerase I British Pharmaceutical Conference Manchester, UK, , 23-SEP-02 - 25-SEP-02 [Details]
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| D. Cairns, F.O. McCarthy, P.W. Groundwater and S.P. Mackay ; (2000) The design of novel ellipticine-amino acid topoisomerase
I inhibitors EORTC Amsterdam, , 07-NOV-00 - 10-NOV-00 [Details]
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