Senior Lecturer
Chemistry
University College Cork
Cork
Ireland

T: +353-21-490-3000
F: +353 21 490 3000
E: H.Moynihan@ucc.ie
W: http://chemweb.ucc.ie/people/hmoynihan.htm
Senior Lecturer In Organic Chemistry
Chemistry
University College Cork
Cork
Ireland

T: +353 21 490 2488
F: +353 21 427 4097
E: h.moynihan@ucc.ie

CV: BSc 1986 (UCC); PhD 1992 (UCC, Dr. D. G. McCarthy); Postdoctoral Research U. Exeter (Prof. S. M. Roberts) and U. Bristol (Dr. J. W. Lewis); Lecturer in Organic Chemistry, Liverpool John Moores University (1994-2001), Lecturer/Snr. Lecturer in Organic Chemistry [Medicinal/Pharmaceutical], UCC (since 2002).

Research Activities: Crystallisation and crystal chemisty of organic compounds; collaboration with Dr. S. E. Lawrence (UCC); Medicinal and Analytical Chemistry; collaborations with Prof. D. W. M. Arrigan (Curtin U., Australia), Prof. A. R. Maguire (UCC), Prof. C. J. Rhodes, Prof. R. J. Hamilton, Dr. C. Rostron and Dr. M. Powell (LJMU).

Research Funding: SFI UREKA, TIDA, SRC and RC funding; including the SFI Synthesis and Solid-state Pharmaceutical Centre, 2013-2018, UL (Prof. B. K. Hodnett, lead-PI), NUIG, TCD, UCD, 13 Pharmaceutical Companies,Total Award >€20M. Also EI Commercialisation Fund Proof of Concept and Innovation Partnerships; IRCSET EPS and Embark awards; FP6 Marie Curie Transfer of Knowledge awards.

Research Output: 52 Peer reviewed publications in CrystEng Comm, Crystal Growth & Design, J. Medicinal Chemistry, Carbohydrate Research and others; h-index:11. 90 Conference presentations of which 30 international. 1 Patent, 1 Licensing Agreement, 2 Commercialisation Awards.

Postgraduate Students and PDRAs: 12 PhD and 2 MSc students graduated; 7 PDRAs. Currently 4 PhD students and 1 PDRA.

Research-influenced Teaching: CM3110 Pharmaceutical Solids & Technology, co-delivered with Dr. S. E. Lawrence; PF1010 Physicochemical Basis of Pharmaceuticals, co-delivered with Dr. A. Crean; Course Coordinator BSc Chemistry of Pharmaceutical Compounds.

Research Interests

Crystallisation and crystal chemistry of organic compounds. Also medicinal, organic and analytical chemistry.

Most pharmaceuticals, foodstuffs and fine chemicals are crystalline solids in their pure forms. Crystallization provides a method of isolating pure compounds in a convenient physical form. Many compounds crystallize in more than one form, i.e. crystal polymorphs and solvates. Crystals can also differ in their shape (morphology, habit), size and size distribution. Controlling crystal form and morphology is very important for pharmaceuticals, foods, pigments and many other high-value fine chemicals.

My research into crystallisation and crystal chemistry of organic includes crystal engineering, crystallisation method development and crystal nucleation studies. The research is often in collaboration with Dr. Simon Lawrence and Prof. Anita Maguire.

Major grant awards for this team include:

-SFI Research Centre funding (Synthesis and Solid-state Pharmaceutical Centre, commenced 2013, in collaboration with UL [Prof. B. K. Hodnett], NUIG, TCD, UCD and several pharmaceutical companies) Total award >€20

-SFI Strategic Research Cluster funding (Solid State Pharmaceutical Cluster 2008-2012; in collaboration with UL, NUIG, TCD, UCD and nine PharmaChemical companies). Total award > €5M

-FP6 Marie Curie Transfer of Knowledge funding (DEPMaB) €500K

-SFI UREKA Site funding, €250M

-Enterprise Ireland Commercialisation Fund Proof of Concept awards >€100K

-IRCSET and other awards.

Specific projects and selected outputs include:

-Research into 'tailor-made' additives for the control of crystal polymorphism:

[Monomeric and polymeric derivatives of 5-aminoisophthalic acid as selective inhibitors of the beta-polymorph of L-glutamic acid, Joanne M. Kelleher, Simon E. Lawrence, Marie T. McAuliffe and Humphrey A. Moynihan, CrystEngComm, 2007, 9(1), 72-77.]

-Crystal engineering with functionalised sugars:

[Supramolecular stacking motifs in the solid state of amide and triazole derivatives of cellobiose, John A. Hayes, Kevin S. Eccles, Simon J. Coles, Simon E. Lawrence, Humphrey A. Moynihan, Carbohydrate Research, 2014, 388, 67-72.]

-Crystallisation process development:

[Humphrey A. Moynihan and Dawn M. Kelly (September 2012). Phenacetin Crystallization: Cooling Regimes and Crystal Morphology, Crystallization - Science and Technology, Marcello Rubens Barsi Andreeta (Ed.), ISBN: 978-953-51-0757-6, InTech]

Since 2002, 7 postgraduate students have obtained PhDs in molecular crystallisation research in my group and are now working in the pharmaceutical industry. 4 Postdoctoral reserchers have worked on these projects.

Other research interests include:

-Synthetic organic chemistry:

[Cyclisations of Benzenesulfanyl Chloride Adducts with Conjugated Silyloxyenones: A New Stereoselective Reaction in the Synthesis of 4,5-Dihydro-3(2H)-Furanones,  Conor C. Collins, Michael F. Cronin, Humphrey A. Moynihan and Daniel G. McCarthy, J. Chem. Soc., Perkin Transactions 1, 1997, 1267 – 1269]

-Medicinal chemistry:

[Fumaroylamino-4,5-epoxymorphinans and Related Opioids with Irreversible m Opioid Receptor Antagonist Effects, Humphrey A. Moynihan, Ian Derrick, Jillian H. Broadbear, Benjamin M. Greedy, Mario D. Aceto, Louis S. Harris, Lauren C. S. Purington, Mark P. Thomas, James H. Woods, John R. Traynor, Stephen M. Husbands, and John W. Lewis, J. Med. Chem., 2012, 55, 9868-6874]

-Analytical chemistry:

[“Spin-Labelling with the Second Hydrogen Radioisotope: Radicals Formed from Squalene by Muonium Addition, Christopher J. Rhodes, Timothy C. Dintinger, Humphrey A. Moynihan and Ivan D. Reid, Free Radical Research, 2000, 33, 75-79; Electrochemistry of dopamine at the polarised liquid/liquid facilitated by an homo-oxo-calix[3]arene ionophore, Grégoire Herzog, Brian McMahon, Myriam Lefoix, Nicholas D. Mullins, Courtney J. Collins, Humphrey A. Moynihan, Damien W. M. Arrigan, J. Electroanal. Chem. 2008, 622(1), 109-114.]

8 Postgraduate students and 4 postdoctoral researchers have worked on these projects.

 





Research Grants

 ProjectFunding
Body
Start DateEnd DateAward
[EI PC/2003/024] {Moynihan Dr. H} NEnterprise Irl02-FEB-0431-JAN-05€56,900.00
IRCSET "Polymorph-selective crystal nucleation inhibition using dedritic tailor-made additives"Irish Research Council for Science, Engineering & Technology (IRCSET)01-OCT-0531-MAR-09€80,915.00
EI "Improved Manufacturing of Pigment Blue 15:0"Enterprise Irl31-DEC-0403-JUL-06€58,300.00
IRCSET 'Hydrogen Bond Patterns & Crystal Polyn'Irish Research Council for Science, Engineering & Technology (IRCSET)01-DEC-0730-SEP-08€72,009.00
Preparation of recrystallized Samples.Industry29-AUG-0031-DEC-11€1,558.00
Optimized crystal morphologies for active pharmaceutical ingredients.Irish Research Council for Science, Engineering & Technology (IRCSET)01-OCT-1030-SEP-13€72,000.00
Pfizer "Crystallisation & Polymorphism"Industry01-JAN-0501-JAN-06€4,000.00
IRCSET "Probing & controlling crystal nucleation in aqueous media"Irish Research Council for Science, Engineering & Technology (IRCSET)01-OCT-0630-SEP-09€72,009.00
EU "Developing Expertise in Pharmaceutical Materials & Biomaterials"European Union02-JAN-0601-JAN-10€526,873.00
Hosts for Electrochemical Ionic Interfacial TransportMiscellaneous01-MAY-0530-APR-06€45,976.00
Process for the preparation of a polymerIndustry30-OCT-0921-DEC-09€14,592.00
Proposal SupportEnterprise Irl18-OCT-1007-DEC-10€8,758.00
SFI 'Solid State Pharmaceuticals Cluster (SSPC)'Science Foundation of Ireland01-DEC-0731-MAY-13€1,470,033.00
EI 'Obtaining Commercial Metastable Forms by Crystal Engineering: Pigment Blue 15:0'Enterprise Irl01-NOV-0731-OCT-08€99,549.00
EI "Development of an ion flux generator; monomer synthesis"Enterprise Irl02-JAN-0631-MAY-07€75,000.00
X-Ray Diffractometer service to Industry account - this account is being set up as a service account to receive monies due mostly from the Pharmaceutical sector. Invoices will be raised in order to collect these funds.Industry01-JUL-0831-DEC-14€16,234.00

Peer Reviewed Journals

YearPublication
(2014)'Supramolecular stacking motifs in the solid state of amide and triazole derivatives of cellobiose'
John A. Hayes, Kevin S. Eccles, Simon J. Coles, Simon E. Lawrence, Humphrey A. Moynihan (2014) 'Supramolecular stacking motifs in the solid state of amide and triazole derivatives of cellobiose'. Carbohydrate Research, 388 :67-72 [Full Text] [Details]
(2013)'Hydrogen bonding in crystal forms of primary amide functionalized glucose and cellobiose'
Humphrey A. Moynihan, John A. Hayes, Kevin S. Eccles, Simon J. Coles, Simon E. Lawrence (2013) 'Hydrogen bonding in crystal forms of primary amide functionalized glucose and cellobiose'. Carbohydrate Research, 374 :29-39 [Full Text] [Details]
(2013)'Crystal Polymorphism of Methyl 2,3,4-tri-O-acetyl-1-O-(trichloroacetimidoyl)-α-d-glucopyranouronate'
John A. Hayes, Kevin S. Eccles, Curtis J. Elcoate, Carla A. Daly, Simon E. Lawrence and Humphrey A. Moynihan (2013) 'Crystal Polymorphism of Methyl 2,3,4-tri-O-acetyl-1-O-(trichloroacetimidoyl)-α-d-glucopyranouronate'. Journal Of Chemical Crystallography, 43 (3):138-143 [DOI] [Full Text] [Details]
(2012)'Fumaroylamino-4,5-epoxymorphinans and Related Opioids with Irreversible mu Opioid Receptor Antagonist Effects'
Humphrey A. Moynihan, Ian Derrick, Jillian H. Broadbear, Benjamin M. Greedy, Mario D. Aceto, Louis S. Harris, Lauren C. S. Purington, Mark P. Thomas, James H. Woods, John R. Traynor, Stephen M. Husbands, and John W. Lewis (2012) 'Fumaroylamino-4,5-epoxymorphinans and Related Opioids with Irreversible mu Opioid Receptor Antagonist Effects'. Journal of Medicinal Chemistry, 55 :9868-9874 [Details]
(2012)'Preparation and characterisation of solid state forms of paracetamol-O-glucuronide'
John A. Hayes, Kevin S. Eccles, Simon E. Lawrence, Humphrey A. Moynihan (2012) 'Preparation and characterisation of solid state forms of paracetamol-O-glucuronide'. Carbohydrate Research, 349 :108-112 [Full Text] [Details]
(2012)'Utilizing Sulfoxide...Iodine Halogen Bonding for Cocrystallization'
Eccles, Kevin; Morrison, Robin; Stokes, Stephen; O'Mahony, Graham; Hayes, John; Kelly, Dawn; O'Boyle, Noel; Fabian, Laszlo; Moynihan, H.; Maguire, Anita; Lawrence, Simon E. (2012) 'Utilizing Sulfoxide...Iodine Halogen Bonding for Cocrystallization'. Crystal Growth and Design, 12 (6):2969-2977 [Full Text] [Details]
(2011)'Cocrystals of fenamic acids with nicotinamide'
Fabian, Laszlo; Hamill, Noel; Eccles, Kevin; Moynihan, H.; Maguire, Anita; McCausland, Linda; Lawrence, Simon E; (2011) 'Cocrystals of fenamic acids with nicotinamide'. Crystal Growth and Design, 11 :3522-3528 [DOI] [Full Text] [Details]
(2011)'Evaluation of the Bruker SMART X2S: crystallography for the nonspecialist?'
Eccles, KS,Stokes, SP,Daly, CA,Barry, NM,McSweeney, SP,O'Neill, DJ,Kelly, DM,Jennings, WB,Dhubhghaill, OMN,Moynihan, HA,Maguire, AR,Lawrence, SE; (2011) 'Evaluation of the Bruker SMART X2S: crystallography for the nonspecialist?'. Journal of Applied Crystallography, 44 :213-215 [DOI] [Full Text] [Details]
(2010)'Crystal polymorphs and transformations of 2-iodo-4-nitroaniline'
Moynihan, H; Kelly, Dawn; Eccles, Kevin; Elcoate, Curtis; Lawrence, Simon E; (2010) 'Crystal polymorphs and transformations of 2-iodo-4-nitroaniline'. Crystal Growth and Design, 10 :4303-4309 [DOI] [Full Text] [Details]
(2010)'Direction of copper phthalocyanine crystallization using in situ generated tethered phthalocyanines'
Moynihan, Humphrey A; Claudon, Geraldine; (2010) 'Direction of copper phthalocyanine crystallization using in situ generated tethered phthalocyanines'. CrystEngComm, [DOI] [Full Text] [Details]
(2010)'Synthesis and evaluation of fully (5-amidoisophthalic acid)- functionalised polyacrylamides as selective inhibitors of the beta crystal polymorph of L-glutamic acid'
Kelly, Dawn M; Moynihan, Humphrey A; (2010) 'Synthesis and evaluation of fully (5-amidoisophthalic acid)- functionalised polyacrylamides as selective inhibitors of the beta crystal polymorph of L-glutamic acid'. Tetrahedron, [DOI] [Details]
(2010)'Mimics of a R22(8) hydrogen-bond dimer motif: synthesis and influence on the crystallisation of sulfathiazole and sulfapyridine'
Lawrence, SE; McAuliffe, MT; Moynihan HA; (2010) 'Mimics of a R22(8) hydrogen-bond dimer motif: synthesis and influence on the crystallisation of sulfathiazole and sulfapyridine'. European Journal of Organic Chemistry, 6 :1134-1141 [Details]
(2010)'Interaction of acridine-calix[4]arene with DNA at the electrified liqui|liquid interface'
Kivlehan, Francine; Lefoix, Myriam; Moynihan, Humphrey A; Thompson, Damien; Ogurtsov, Vladimir I; Herzog, Gregoire; Arrigan, Damien WM; (2010) 'Interaction of acridine-calix[4]arene with DNA at the electrified liqui|liquid interface'. Electrochimica Acta, 55 (9):3348-3354 [Details]
(2009)'Study of electrochemical phosphate sensing systems: Spectrometric, potentiometric and voltammetric evaluation'
Francine Kivlehan, Wade J. Mace, Humphrey A. Moynihan*, Damien W. M. Arrigan; (2009) 'Study of electrochemical phosphate sensing systems: Spectrometric, potentiometric and voltammetric evaluation'. Electrochimica Acta, 54 :1919-1924 [Details]
(2009)'14beta-O-Cinnamoylnaltrexone and Related Dihydrocodeinones are Mu Opioid Partial Agonists with predominant Antagonist Activity'
H. Moynihan, A. R. Jules, B. M. Greedy, D. Rennison, J. H. Broadbear, L. Purington, J. R. Traynor, J. H. Woods, J. W. Lewis, and S. M. Husbands; (2009) '14beta-O-Cinnamoylnaltrexone and Related Dihydrocodeinones are Mu Opioid Partial Agonists with predominant Antagonist Activity'. Journal of medicinal chemistry, 52 (6):1553-1557 [Details]
(2009)'Selective Nonomolar Detection of Dopamine Using a Boron-Doped Diamond Electrode Modified with an Electropolymerized Sulfobutylether-beta-cyclodextrin-Doped Poly(N-acetyltyramine) and Polypyrrole Composite Film'
F. J. Shang, :L. Zhou, K. A. Mahmoud, S. Hrapovic, Y. L. Liu, H. A. Moynihan, J. D. Glennon, J. H. T. Luong (2009) 'Selective Nonomolar Detection of Dopamine Using a Boron-Doped Diamond Electrode Modified with an Electropolymerized Sulfobutylether-beta-cyclodextrin-Doped Poly(N-acetyltyramine) and Polypyrrole Composite Film'. Analytical Chemistry, 81 (10):4089-4098 [Details]
(2008)'Electrochemistry of dopamine at the polarised liquid/liquid facilitated by an homo-oxo-calix[3]arene ionophore'
, Grégoire Herzog, Brian McMahon, Myriam Lefoix, Nicholas D. Mullins, Courtney J. Collins, Humphrey A. Moynihan, Damien W. M. Arrigan; (2008) 'Electrochemistry of dopamine at the polarised liquid/liquid facilitated by an homo-oxo-calix[3]arene ionophore'. J. Electroanal. Chem, 622 (1):109-114 [Details]
(2008)'Effect of 1-Deoxy-D-lactose upon the Crystallization of D-Lactose'
Kevin P. Guiry, Simon J. Coles, Humphrey A. Moynihan, and Simon E. Lawrence; (2008) 'Effect of 1-Deoxy-D-lactose upon the Crystallization of D-Lactose'. Crystal Growth and Design, 8 (11):3927-3934 [DOI] [Full Text] [Details]
(2007)'Monomeric and polymeric derivatives of 5-aminoisophthalic acid as selective inhibitors of the beta-polymorph of L-glutamic acid'
J.M. Kelleher, S.E. Lawrence, M.T. McAuliffe and H.A. Moynihan; (2007) 'Monomeric and polymeric derivatives of 5-aminoisophthalic acid as selective inhibitors of the beta-polymorph of L-glutamic acid'. CrystEngComm, 9 (1):72-77 [Details]
(2007)'Potentiometric evaluation of calix[4]arene anion receptors in membrane electrodes: Phosphate detection'
Francine Kivlehan; Wade J. Mace; Humphrey A. Moynihan, Damien W. M. Arrigan; (2007) 'Potentiometric evaluation of calix[4]arene anion receptors in membrane electrodes: Phosphate detection'. Anal. Chim. Acta, 585 :154-160 [Details]
(2007)'Crystal polymorphism of pharmceuticals: probing crystal nucleation at the molecular level'
Guiry, K.P.; Kelleher, J.M.; Lawrence, S.E.; McAuliffe, M.T.; Moynihan, H.A; Ryan, A.L.;; (2007) 'Crystal polymorphism of pharmceuticals: probing crystal nucleation at the molecular level'. Journal of Enzyme Inhibition and Medicinal Chemistry, in press (*):*-* [Details]
(2007)'Studies on the preparation and crystal polymorphism of 2-acetamidobenzamide and related compounds'
Kelleher, JM,McAuliffe, MT,Moynihan, HA,Mullins, ND (2007) 'Studies on the preparation and crystal polymorphism of 2-acetamidobenzamide and related compounds'. Arkivoc, :209-226 [Details]
(2007)'Biotransformation and stereoselective synthesis of pharmaceutical molecules from linoleic acid'
O. Muhammad Nor, N. N. Nor, H. Moynihan, R. Hamilton (2007) 'Biotransformation and stereoselective synthesis of pharmaceutical molecules from linoleic acid'. Biotechnology, 6 (2):283-287 [Details]
(2006)'Effect of the steric demand and hydrogen bonding capacity of additives on the crystal polymorphism of sulfathiazole'
, Joanne M. Kelleher, Simon E. Lawrence and Humphrey A. Moynihan; (2006) 'Effect of the steric demand and hydrogen bonding capacity of additives on the crystal polymorphism of sulfathiazole'. CrystEngComm, 8 :327-332 [Details]
(2006)'Alginate-Chitosan Beads: Determining the Influence of Processing Parameters on Bead Formation'
Blackshields, C. A, Oliveira, J., Moynihan, H.A., Crean, A.M; (2006) 'Alginate-Chitosan Beads: Determining the Influence of Processing Parameters on Bead Formation'. J. Pharm. Pharmacol, Supplement 1 [Details]
(2006)'Structural Determinants of Opioid Activity in Derivatives of 14-Aminomorphinones: Effect of Substitution in the Aromatic Ring of Cinnamoylaminomorphinones and Codeinones'
, Nick P. R. Nieland, Humphrey A. Moynihan, Simon Carrington, Jillian Broadbear, James H. Woods, John R. Traynor, Stephen M. Husbands*, and John W. Lewis; (2006) 'Structural Determinants of Opioid Activity in Derivatives of 14-Aminomorphinones: Effect of Substitution in the Aromatic Ring of Cinnamoylaminomorphinones and Codeinones'. J. Med. Chem, 49 (17):5333-5338 [Details]
(2006)'Structural determinants of opioid activity in derivatives of 14-aminomorphinones: Effects of changes to the chain linking of the C-14-amino group to the aryl ring'
David Rennison, Humphrey Moynihan, John R. Traynor, John W. Lewis, Stephen M. Husbands*,; (2006) 'Structural determinants of opioid activity in derivatives of 14-aminomorphinones: Effects of changes to the chain linking of the C-14-amino group to the aryl ring'. J. Med. Chem, 49 (20):6104-6110 [Details]
(2005)'Preparation and stereochemical integrity of certain thioesters of 2-arylpropionic acids and related compounds'
Patrick E. Hanrahan and Humphrey A. Moynihan; (2005) 'Preparation and stereochemical integrity of certain thioesters of 2-arylpropionic acids and related compounds'. J. Pharm. Pharmacol, 57 :1619-1627 [Details]
(2003)'Scaling-up the production of 13S-hydroxy-9Z,11E-octadecadienoic acid (13S-HODE) through chemoenzymatic technique'
Muhammad N. Omar, Humphrey A. Moynihan and Richard J. Hamilton*,; (2003) 'Scaling-up the production of 13S-hydroxy-9Z,11E-octadecadienoic acid (13S-HODE) through chemoenzymatic technique'. Bulletin of the Korean Chemical Society, 24 (3):397-399 [Details]
(2003)'Asymmetric Sharpless epoxidation of 13S-hydroxy-9Z,11E-octadecadienoic acid'
Muhammad N. Omar, Humphrey A. Moynihan and Richard J. Hamilton; (2003) 'Asymmetric Sharpless epoxidation of 13S-hydroxy-9Z,11E-octadecadienoic acid'. European Journal of Lipid Science and Technology, 105 (1):43-44 [Details]
(2003)'Stereoselective preparations of epoxy-, fluoro- and related derivatives of ricinoleic acid and 13(S)-hydroxyoctadeca-9(Z),11(E)-dienoic acid'
Muhammad Nor Bin Omar, Richard J. Hamilton and Humphrey A. Moynihan; (2003) 'Stereoselective preparations of epoxy-, fluoro- and related derivatives of ricinoleic acid and 13(S)-hydroxyoctadeca-9(Z),11(E)-dienoic acid'. ARKIVOC, (7):190-199 [Details]
(2002)'Spectroscopic characterisation of orthorhombic and monoclinic paracetamol'
, Humphrey. A. Moynihan* and Iain. P. O'Hare; (2002) 'Spectroscopic characterisation of orthorhombic and monoclinic paracetamol'. International Journal of Pharmaceutics, 247 :179-185 [Details]
(2001)'Synthesis and hydrolytic behaviour of glycerol-1,2-diibuprofenate-3-nitrate, a putative pro-drug of ibuprofen and glycerol-1-nitrate'
M. J. Ingram, H. A. Moynihan*, M. W. Powell, C. Rostron; (2001) 'Synthesis and hydrolytic behaviour of glycerol-1,2-diibuprofenate-3-nitrate, a putative pro-drug of ibuprofen and glycerol-1-nitrate'. J. Pharm. Pharmacol, 53 :345-350 [Details]
(2001)'Self-reactivity of s-triazine and its radical cation: an electron/proton transfer process driven by ionizing radiation'
C. J. Rhodes* and H. A. Moynihan; (2001) 'Self-reactivity of s-triazine and its radical cation: an electron/proton transfer process driven by ionizing radiation'. Magnetic Resonance in Chemistry, 39 (3):133-136 [Details]
(2000)'Compaction and thermal properties of a series of ibuprofen salts'
Madeline R. Whelan, Matthew J. Ingram, Claire Madden, James L. Ford*, Humphrey A. Moynihan; (2000) 'Compaction and thermal properties of a series of ibuprofen salts'. J.Pharm. Pharmacol, 52 (Supplement) [Details]
(2000)'Spin-Labelling with the Second Hydrogen Radioisotope: Radicals Formed from Squalene by Muonium Addition'
Christopher J. Rhodes*, Timothy C. Dintinger, Humphrey A. Moynihan and Ivan D. Reid, ; (2000) 'Spin-Labelling with the Second Hydrogen Radioisotope: Radicals Formed from Squalene by Muonium Addition'. Free Radical Research, 33 :75-79 [Details]
(2000)'Radiolabelling Studies of Free Radical Reactions using Muonium (the Second Hydrogen Radioisotope): Evidence of a Direct Antioxidant Role for Vitamin K in Repair of Oxidative Damage to Lipids'
, Christopher J. Rhodes*, Timothy C. Dintinger and Humphrey A. Moynihan; (2000) 'Radiolabelling Studies of Free Radical Reactions using Muonium (the Second Hydrogen Radioisotope): Evidence of a Direct Antioxidant Role for Vitamin K in Repair of Oxidative Damage to Lipids'. Magnetic Resonance in Chemistry, 38 :646-649 [Details]
(2000)'14-Cinnamoyl and fumaroyl derivatives of naltrexone'
S. M. Husbands, H. Moynihan, J. H. Woods, J. R. Traynor, J. Broadbear, H. Plumer, J. W. Lewis (2000) '14-Cinnamoyl and fumaroyl derivatives of naltrexone'. Drug and alcohol dependence, 60 (Supplementary 1):S96-S97 [Details]
(1999)'Hydrolysis of ibuprofen propyl ester in a physiologically-based model with direct analysis by reverse phase HPLC'
. J. Ingram, H. A. Moynihan*, M. W. Powell and C. Rostron; (1999) 'Hydrolysis of ibuprofen propyl ester in a physiologically-based model with direct analysis by reverse phase HPLC'. J. Pharm. Pharmacol, 51 (Supplement) [Details]
(1998)'Improved Selective Protections of L-Arginine'
Humphrey A. Moynihan and WeipingYu,; (1998) 'Improved Selective Protections of L-Arginine'. Synthetic Communications, 28 :17-23 [Details]
(1998)'Guanidino-substituted arginines via N-silyl intermediates'
, H. A. Moynihan* and W. Yu, ; (1998) 'Guanidino-substituted arginines via N-silyl intermediates'. J. Pharm. Pharmacol, 50 (Supplement) [Details]
(1998)'Synthesis and nitration of ibuprofen 1-monoglyceride'
M. J. Ingram, H. A. Moynihan and C. Rostron, ; (1998) 'Synthesis and nitration of ibuprofen 1-monoglyceride'. J. Pharm. Pharmacol, 50 (Supplement) [Details]
(1998)'Alkoxycarbonylation and Selective Deprotection of N-Silyl Derivatives of L-Arginine'
Humphrey A. Moynihan+ and Weiping Yu; (1998) 'Alkoxycarbonylation and Selective Deprotection of N-Silyl Derivatives of L-Arginine'. Tetrahedron Letters, 39 :3349-3352 [Details]
(1997)'Cyclisations of Benzenesulfanyl Chloride Adducts with Conjugated Silyloxyenones: A New Stereoselective Reaction in the Synthesis of 4,5-Dihydro-3(2H)-Furanones'
Conor C. Collins, Michael F. Cronin, Humphrey A. Moynihan and Daniel G. McCarthy; (1997) 'Cyclisations of Benzenesulfanyl Chloride Adducts with Conjugated Silyloxyenones: A New Stereoselective Reaction in the Synthesis of 4,5-Dihydro-3(2H)-Furanones'. J. Chem. Soc., Perkin Transactions 1, :1267-1269 [Details]
(1996)'Potential Irreversible Ligands for Opioid Receptors. Cinnamoyl Derivatives of -Naltrexamine'
, Ian Derrick, John W. Lewis*, Humphrey A. Moynihan, Gillian Broadbear and James H. Woods; (1996) 'Potential Irreversible Ligands for Opioid Receptors. Cinnamoyl Derivatives of -Naltrexamine'. J. Pharm. Pharmacol, 48 :192-196 [Details]
(1996)'6N-Cinnamoyl -Naltrexamine and its para-Nitro Derivatives. High Efficacy -Opiate Agonists with Weak Antagonist Action'
Ian Derrick, Humphrey A. Moynihan and John W. Lewis; (1996) '6N-Cinnamoyl -Naltrexamine and its para-Nitro Derivatives. High Efficacy -Opiate Agonists with Weak Antagonist Action'. Bio-organic and Medicinal Chemistry Letters, 6 :167-172 [Details]
(1995)'Molecular Modelling of Fumarimido and Cinnamoylamido Derivatives in Epoxy- Morphinans. Correlation with Pharmacological Profiles'
Neil G. Piggot, Ian Derrick, Humphrey A. Moynihan, Stephen M. Husbands, John W. Lewis* and James H. Woods; (1995) 'Molecular Modelling of Fumarimido and Cinnamoylamido Derivatives in Epoxy- Morphinans. Correlation with Pharmacological Profiles'. Analgesia, 1 :386-389 [Details]
(1994)'Synthesis and Biological Activity of the Novel Nitric Oxide Synthase Inhibitor N'-Hydroxy-N-methyl-L-arginine'
Humphrey A. Moynihan, Stanley M. Roberts*, Hazel Weldon Graham H. Allcock, Erik E. Anggard and Timothy D. Warner; (1994) 'Synthesis and Biological Activity of the Novel Nitric Oxide Synthase Inhibitor N'-Hydroxy-N-methyl-L-arginine'. J. Chem. Soc.,Perkin Transactions 1, :769-771 [Details]
(1994)'Preparation of Some Novel S-Nitroso Compounds as Potential Slow-release Agents of Nitric Oxide in vivo'
Humphrey A. Moynihan and Stanley M. Roberts; (1994) 'Preparation of Some Novel S-Nitroso Compounds as Potential Slow-release Agents of Nitric Oxide in vivo'. J. Chem. Soc.,Perkin Transactions 1, :797-805 [Details]

Book Chapters

YearPublication
(2015)'Impurity exclusion and retention during crystallisation and recrystallisation; the phenacetin by ethylation of paracetamol process'
Danielle E. Horgan, Lorraine M. Crowley, Stephen P. Stokes, Simon E. Lawrence and Humphrey A. Moynihan (2015) 'Impurity exclusion and retention during crystallisation and recrystallisation; the phenacetin by ethylation of paracetamol process' In: Yitzhak Mastai (eds). Crystallization. Rijeka: InTech. [Details]
(2012)'Phenacetin Crystallization: Cooling Regimes and Crystal Morphology'
Humphrey A. Moynihan and Dawn M. Kelly (2012) 'Phenacetin Crystallization: Cooling Regimes and Crystal Morphology' In: Crystallization Science and Technology. Croatia: InTech. [Details]
(2005)'Comprehensive Organic Functional Group Transformations'
Humphrey A. Moynihan; (2005) 'Comprehensive Organic Functional Group Transformations' In: Alkyl Metals. Oxford: Elsevier. [Details]

Books

YearPublication
(2009)The Physicochemical Basis of Pharmaceuticals.
Humphrey Moynihan and Abina Crean; (2009) The Physicochemical Basis of Pharmaceuticals. Oxford: Oxford University Press. [Details]

Conference Contributions

YearPublication
(2014)XXIIth European Conference of the Groupement des Pharmacochimistes de l’Arc Atlantique,
D. E. Horgan and H. A. Moynihan (2014) Ketoprofen Tris and Related Salts: Phase Behaviour and Pharmaceutical Potential. [Poster Presentation], XXIIth European Conference of the Groupement des Pharmacochimistes de l’Arc Atlantique, University of Nantes . [Details]
(2014)Quarterly Technical Meeting of the SFI Synthesis and Solid-state Pharmaceutical Centre,
Danielle Horgan and Humphrey Moynihan (2014) T5 Impurity Effects in Crystallisation. [Oral Presentation], Quarterly Technical Meeting of the SFI Synthesis and Solid-state Pharmaceutical Centre, UCC , 03-DEC-14. [Details]
(2014)SFI Synthesis and Solid State Pharmaceutical Centre Quarterly Technical Meeting,
Humphrey Moynihan, Åke Rasmuson, Kieran Hodnett, Alan Ryder, Simon Lawrence, Andrea Erxleben, John Hayes, Danielle Horgan, Boyan Li, Hien Nguyen (2014) T5 Impurity Effects in Crystallisation. [Oral Presentation], SFI Synthesis and Solid State Pharmaceutical Centre Quarterly Technical Meeting, University College Dublin . [Details]
(2014)XXIIth European Conference of the Groupement des Pharmacochimistes de l’Arc Atlantique,
L. M. Shanahan and H. A. Moynihan (2014) N,N’’-Bisalkyl Quinacridones: Solubilised Pigments for Pharmaceutical and Biological Application. [Poster Presentation], XXIIth European Conference of the Groupement des Pharmacochimistes de l’Arc Atlantique, University of Nantes . [Details]
(2014)SFI Synthesis and Solid State Pharmaceutical Centre Quarterly Technical Meeting,
Louise Shanahan and Humphrey Moynihan (2014) P5 Crystallisation Kinetics WP1 Solution Structure WP2 Nucleation. [Oral Presentation], SFI Synthesis and Solid State Pharmaceutical Centre Quarterly Technical Meeting, UCC , 03-DEC-14. [Details]
(2013)3rd Almac/UCC Joint Symposium,
Humphrey Moynihan (2013) Crystal Chemistry of Sugar Derivatives. [Oral Presentation], 3rd Almac/UCC Joint Symposium, University College Cork , 09-SEP-13. [Details]
(2013)UCC School of Pharmacy Research Day,
Nicholas D. Mullins, Anita R. Maguire, Humphrey A. Moynihan, Florence O. McCarthy, Simon E. Lawrence, Abina Crean, and Jonathan Thompson (2013) Degradation of Gentamicin Sulfate on Coated Titanium Surfaces. [Poster Presentation], UCC School of Pharmacy Research Day, University College Cork , 23-SEP-13. [Details]
(2013)21st European Conferences of the Groupment des Pharmacochimistes de l'Arc Atlantiques,
Danielle Horgan, Kevin Eccles, Humphrey Moynihan (2013) Impurity impact on crystallisation of an active pharmaceutical ingredient. [Poster Presentation], 21st European Conferences of the Groupment des Pharmacochimistes de l'Arc Atlantiques, Lille , 05-JUN-13 - 07-JUN-13. [Details]
(2013)21st European Conferences of the Groupment des Pharmacochimistes de l'Arc Atlantiques,
Lorna Lennon, Humphrey Moynihan (2013) Deoxycellodextrins as putative isostructures of cellulose polymorphs. [Poster Presentation], 21st European Conferences of the Groupment des Pharmacochimistes de l'Arc Atlantiques, Lille , 05-JUN-13 - 07-JUN-13. [Details]
(2013)21st European Conferences of the Groupment des Pharmacochimistes de l'Arc Atlantiques,
John A. Hayes and Humphrey A. Moynihan (2013) The synthesis of some alanine and phenylglycine oligopeptides and polyarginine carboxylates. [Poster Presentation], 21st European Conferences of the Groupment des Pharmacochimistes de l'Arc Atlantiques, Lille , 05-JUN-13 - 07-JUN-13. [Details]
(2013)1st Technical Meeting of the Synthesis and Solid-State Pharmaceutical Centre,
Humphrey A. Moynihan (2013) T5 Impurities in Crystallisation: Overview and Recent Work. [Oral Presentation], 1st Technical Meeting of the Synthesis and Solid-State Pharmaceutical Centre, University College Cork , 10-DEC-13. [Details]
(2012)10th International Workshop on the Crystal Growth of Organic Materials,
Lorna A. Lennon, Dawn M. Kelly, Kevin S. Eccles, Simon E. Lawrence and Humphrey A. Moynihan (2012) Building a common structural motif for glycoside derivatives. [Poster Presentation], 10th International Workshop on the Crystal Growth of Organic Materials, University of Limerick , 11-JUN-12 - 14-JUN-12. [Details]
(2012)Symposium on Recent Advances in Synthesis and Chemical Biology XI,
Lorna A. Lennon, Humphrey A. Moynihan (2012) Small scale analogues of cellulose as isostructures of cellulose polymorphs. [Poster Presentation], Symposium on Recent Advances in Synthesis and Chemical Biology XI, Royal College of Surgeons, Dublin , 14-DEC-12 - 14-DEC-12. [Details]
(2012)10th International Workshop on the Crystal Growth of Organic Materials,
Humphrey A. Moynihan, John Hayes, Lorna Lennon, Kevin Eccles, Simon E. Lawrence (2012) Approaches to crystal engineering with functionalised sugars. [Oral Presentation], 10th International Workshop on the Crystal Growth of Organic Materials, University of Limerick , 11-JUN-12 - 14-JUN-12. [Details]
(2012)10th International Workshop on the Crystal Growth of Organic Materials,
John A. Hayes, Humphrey A. Moynihan (2012) Supramolecular motifs in glucose oligosaccharides bearing primary amides on the glycosidic side chains. [Poster Presentation], 10th International Workshop on the Crystal Growth of Organic Materials, University of Limerick , 11-JUN-12 - 14-JUN-12. [Details]
(2012)Symposium on Recent Advances in Synthesis and Chemical Biology XI,
Humphrey A. Moynihan and John Hayes (2012) The synthesis of some alanine and phenylglycine oligopeptides and polyarginine carboxylates. [Poster Presentation], Symposium on Recent Advances in Synthesis and Chemical Biology XI, Royal College of Surgeons, Dublin , 14-DEC-12 - 14-DEC-12. [Details]
(2011)XXth Conference of the Groupment des Pharmacochimistes de l'Arc Atlantiques,
L. A. Lennon, K. S. Eccles, S. E. Lawrence, H. A. Moynihan (2011) Crystal structures of aryl glycosides, glucuronides and cellobiosides. [Poster Presentation], XXth Conference of the Groupment des Pharmacochimistes de l'Arc Atlantiques, UCC , 01-SEP-11 - 02-SEP-11. [Details]
(2011)RSC Carbohydrate & Bioorganic Groups Joint Spring Meeting,
John Hayes, Humphrey A. Moynihan, Simon E. Lawrence, Kevin Eccles (2011) Synthetic methodologies, crystallisation and solid state investigations of glucuronides and their intermediates. [Poster Presentation], RSC Carbohydrate & Bioorganic Groups Joint Spring Meeting, King's College London , 05-APR-11. [Details]
(2011)Bruker/ABCRF Structure Solutions Seminar,
Humphrey Moynihan (2011) Crystal Chemistry of some Bio-active Sugars. [Oral Presentation], Bruker/ABCRF Structure Solutions Seminar, UCC , 17-NOV-11. [Details]
(2011)XXth Conference of the Groupment des Pharmacochimistes de l'Arc Atlantiques,
Danielle E. Horgan, Dawn, M. Kelly, Kevin S. Eccles, Robert Aherne, Denis Ring, Abina Crean, Simon E. Lawrence, Humphrey A. Moynihan (2011) Phenacetin as a Model Compound for Particle Engineering. [Poster Presentation], XXth Conference of the Groupment des Pharmacochimistes de l'Arc Atlantiques, UCC , 01-SEP-11 - 02-SEP-11. [Details]
(2011)British Association for Crystal Growth Annual Conference 2011,
D. E. Horgan, D. M. Kelly, K. S. Eccles, S. E. Lawrence, H. A. Moynihan, R. Aherne, D. Ring, A. Crean (2011) Phenacetin as a Model Compound for Particle Engineering. [Poster Presentation], British Association for Crystal Growth Annual Conference 2011, University College London , 10-JUL-11 - 12-JUL-11. [Details]
(2011)XXth Conference of the Groupment des Pharmacochimistes de l'Arc Atlantiques,
J. A. Hayes, H. A. Moynihan, S. E. Lawrence, K. S. Eccles (2011) Synthesis and solid-state characterisation of N-substituted derivatives of cellobiose. [Poster Presentation], XXth Conference of the Groupment des Pharmacochimistes de l'Arc Atlantiques, UCC , 01-SEP-11 - 02-SEP-11. [Details]
(2011)RSC Carbohydrate & Bioorganic Groups Joint Spring Meeting,
Dawn M. Kelly, Lorna A. Lennon, Matthew M. O'Neill, Kevin S. Eccles, Simon E. Lawrence and Humphrey A. Moynihan (2011) Crystal structures of glycoside derivatives on route to glucuronide formation via TEMPO oxidation. [Poster Presentation], RSC Carbohydrate & Bioorganic Groups Joint Spring Meeting, King's College London, , 05-APR-11. [Details]
(2011)British Association for Crystal Growth Annual Conference 2011,
D. M. Kelly, L. A. Lennon, M. M. O'Neill, K. S. Eccles, S. E. Lawrence, H. A. Moynihan (2011) Crystal Structures of Aryl Glycosides, Glucuronides and Cellobiosides. [Poster Presentation], British Association for Crystal Growth Annual Conference 2011, University College London , 10-JUL-11 - 12-JUL-11. [Details]
(2011)Control and Prediction of the Organic Solid State Open Meeting,
L. Fábián, N. Hamill, K. S. Eccles, H. A. Moynihan, A. R. Maguire, L. McCausland, S. E. Lawrence (2011) Fenamic acid nicotinamide cocrystals: What can we predict?,. [Poster Presentation], Control and Prediction of the Organic Solid State Open Meeting, UCL London , 30-MAR-11. [Details]
(2010)19th European Conference of the Group of Medicinal Chemists of the Atlantic Arc - GP2A,
Lennon, L.A., Moynihan, H.A., (2010) The preparation of glucuronide derivatives. [Poster Presentation], 19th European Conference of the Group of Medicinal Chemists of the Atlantic Arc - GP2A, Rouen , 01-SEP-10 - 02-SEP-11. [Details]
(2010)19th European Conference of the Group of Medicinal Chemists of the Atlantic Arc - GP2A,
John Hayes, Humphrey A. Moynihan, Simon Lawrence, Curtis Elcoate and Kevin Eccles (2010) Synthetic methodologies, crystallisation and solid state investigations of glucuronides and their intermediates. [Poster Presentation], 19th European Conference of the Group of Medicinal Chemists of the Atlantic Arc - GP2A, Rouen , 01-SEP-10 - 02-SEP-10. [Details]
(2010)Almac/UCC Joint Symposium on Pharmaceutical Polymorphs and Cocrystallization,
Dawn Kelly and H. A. Moynihan (2010) Crystallization using the HEL AutoLab and LaserTrack system. [Oral Presentation], Almac/UCC Joint Symposium on Pharmaceutical Polymorphs and Cocrystallization, UCC , 28-APR-10. [Details]
(2010)19th European Conference of the Group of Medicinal Chemists of the Atlantic Arc - GP2A,
Dawn M. Kelly, Curtis Elcoate, Kevin Eccles, Simon E. Lawrence, Humphrey A. Moynihan (2010) Optimising pharmaceutical solids; a critical step on the route from molecules to medicines. [Oral Presentation], 19th European Conference of the Group of Medicinal Chemists of the Atlantic Arc - GP2A, Rouen , 01-SEP-10 - 02-SEP-10. [Details]
(2010)UCC College of Medicine and Health Conference,
Dawn M. Kelly and Humphrey A. Moynihan (2010) Optimizing pharmaceutical solids; a critical step on the route from molecules to medicines. [Oral Presentation], UCC College of Medicine and Health Conference, UCC , 16-JUN-10. [Details]
(2009)7th Annual Eli Lilly Research Symposium in Organic & Pharmaceutical Chemistry,
Dawn Kelly and H. A. Moynihan (2009) PXRD and NMR studies on the crystallization of paracetamol derivatives. [Oral Presentation], 7th Annual Eli Lilly Research Symposium in Organic & Pharmaceutical Chemistry, UCC , 02-OCT-09. [Details]
(2009)British Association of Crystal Growth, 40th Anniversary Conference,
J. Hayes, H. A. Moynihan (2009) Crystallisation and crystal forms of Paracetamol-O-glucuronide. [Poster Presentation], British Association of Crystal Growth, 40th Anniversary Conference, University of Bristol , 06-SEP-09 - 08-SEP-09. [Details]
(2009)British Association of Crystal Growth, 40th Anniversary Conference,
G. Claudon, H. A. Moynihan (2009) New process for the preparation of the alpha polymorph of copper phthalocyanine. [Poster Presentation], British Association of Crystal Growth, 40th Anniversary Conference, University of Bristol , 06-SEP-09 - 08-SEP-09. [Details]
(2009)British Association of Crystal Growth, 40th Anniversary Conference,
D. M. Kelly and H. A. Moynihan (2009) Probing and controlling the crystallisation of 2-iodo-4-nitroaniline. [Poster Presentation], British Association of Crystal Growth, 40th Anniversary Conference, University of Bristol , 06-SEP-09 - 08-SEP-09. [Details]
(2009)Quaterly Technical Meeting of the Solid State Pharmaceutical Cluster,
John Hayes and H. A. Moynihan (2009) The Synthesis, Crystallisation and Crystal Forms of Paracetamol-O-Glucuronide. [Oral Presentation], Quaterly Technical Meeting of the Solid State Pharmaceutical Cluster, University of Limerick , 03-SEP-09. [Details]
(2009)British Association of Crystal Growth, 40th Anniversary Conference,
S. P. McSweeney, H. A. Moynihan, S. E. Lawrence (2009) Investigations into the crystal chemistry of sulfonilamides and their phenol and thiophenol analogues. [Poster Presentation], British Association of Crystal Growth, 40th Anniversary Conference, University of Bristol , 06-SEP-09 - 08-SEP-09. [Details]
(2009)Synthesis of Biologically Active Molecules V,
Humphrey A. Moynihan (2009) Bioactive molecules in the crystalline solid state. [Oral Presentation], Synthesis of Biologically Active Molecules V, UCC , 14-MAY-09. [Details]
(2009)SSPC Quarterly Technical Meeting,
Dawn Kelly and H. A. Moynihan (2009) PXRD and NMR studies on the crystallization of paracetamol derivatives. [Oral Presentation], SSPC Quarterly Technical Meeting, NUI Galway , 10-MAR-09. [Details]
(2009)Polymorphism & Crystallisation Conference,,
Andrea L. Ryan, Marie T. McAuliffe and H.A. Moynihan (2009) Tailor-made polymeric additives as crystallisation controlling agents. [Poster Presentation], Polymorphism & Crystallisation Conference,, Brussels , 19-MAR-09 - 20-MAR-09. [Details]
(2009)Polymorphism & Crystallisation Conference,
Kevin P. Guiry, S. E. Lawrence and H. A. Moynihan (2009) Aspects of lactose crystallisation. [Poster Presentation], Polymorphism & Crystallisation Conference, Brussels , 19-MAR-09 - 20-MAR-09. [Details]
(2009)Electrochemistry conference organised by the Société Française de Chimie,
Grégoire Herzog, Francine Kivlehan, Myriam Lefoix, Jörg Strutwolf, Damien Thompson, Vladimir I. Ogurtsov, Humphrey A. Moynihan, Damien W.M. Arrigan (2009) DNA and calix[4]arene-acridine interactions at the liquid | liquid interface. [Poster Presentation], Electrochemistry conference organised by the Société Française de Chimie, Romania , 02-SEP-09 - 04-SEP-09. [Details]
(2009)Institute of Chemistry of Ireland Annual Congress,
H. A. Moynihan (2009) Molecular crystalline solids; the physical form of the chemistry – biology interface. [Oral Presentation], Institute of Chemistry of Ireland Annual Congress, University College Dublin , 22-MAY-09. [Details]
(2008)Solid State Pharmaceutical Cluster, General Meeting,
Marie T. McAuliffe and Humphrey A. Moynihan; (2008) Effect on sulfathiazole crystallization of mimics of the R22(8) hydrogen bond motif. [Oral Presentation], Solid State Pharmaceutical Cluster, General Meeting, University of Limerick , 09-MAY-08 - 09-MAY-08. [Details]
(2007)Arrigan 58th Annual Meeting of the International Society of Electrochemistry,
Grégoire Herzog, Brian McMahon, Myriam Lefoix, Humphrey Moynihan, Damien W.M; (2007) Dopamine detection at the polarised liquid-liquid interface using an oxacalixarene. [Oral Presentation], Arrigan 58th Annual Meeting of the International Society of Electrochemistry, Banff, Canada , 09-SEP-07 - 14-SEP-07. [Details]
(2007)British Association for Crystal Growth & Irish Association for Crystal Growth Conference 2007,
Sharon McSweeney, S. E. Lawrence & H. A. Moynihan; (2007) Hydrogen bonding and polymorphism in sulfanilamide-like sulfonamides. [Oral Presentation], British Association for Crystal Growth & Irish Association for Crystal Growth Conference 2007, University College Dublin , 03-SEP-07 - 04-SEP-07. [Details]
(2007)British Association for Crystal Growth & Irish Association for Crystal Growth, Conference 2007,,
Dawn Kelly, Marie McAuliffe and H. A. Moynihan; (2007) Probing the effect of additives on the crystallization of L-Glutamic acid. [Oral Presentation], British Association for Crystal Growth & Irish Association for Crystal Growth, Conference 2007,, University College Dublin, , 03-SEP-07 - 04-SEP-07. [Details]
(2007)British Association for Crystal Growth & Irish Association for Crystal Growth, Conference 2007,,
Humphrey A. Moynihan; (2007) Molecular-level approaches to crystal polymorph control. [Oral Presentation], British Association for Crystal Growth & Irish Association for Crystal Growth, Conference 2007,, University College Dublin , 03-SEP-07 - 04-SEP-07. [Details]
(2007)59th Irish Universities Chemistry Research Colloquium,
K.P. Guiry, S.E. Lawrence & Humphrey A. Moynihan; (2007) Aspects of D-lactose crystallization,. [Oral Presentation], 59th Irish Universities Chemistry Research Colloquium, Dublin City University , 13-JUN-07 - 15-JUN-07. [Details]
(2007)29th All-Ireland Schools of Pharmacy Research Seminar,
K.P. Guiry, S.J. Coles, S.E. Lawrence, & H.A. Moynihan; (2007) Aspects of D-Lactose Crystallization. [Oral Presentation], 29th All-Ireland Schools of Pharmacy Research Seminar, RCSI Dublin , 02-APR-07 - 03-APR-07. [Details]
(2007)European Federation of Chemical Engineers Working Party on Crystallization, Technical Meeting,
K.P. Guiry, S.J. Coles, S.E. Lawrence, & H.A. Moynihan; (2007) Aspects of D-Lactose Crystallization. [Oral Presentation], European Federation of Chemical Engineers Working Party on Crystallization, Technical Meeting, University College Dublin , 23-MAR-07 - 23-MAR-07. [Details]
(2006)Developing Expertise in Pharmaceutical Materials and Bio-materials,
Humphrey A. Moynihan; (2006) Developing Expertise in Pharmaceutical Materials and Bio-materials. [Oral Presentation], Developing Expertise in Pharmaceutical Materials and Bio-materials, Weizmann Institute of Science, Israel , 24-SEP-06 - 24-SEP-07. [Details]
(2006)Groupement des Pharmacochimistes de l'Arc Atlantique, 15th Conference,
K.P. Guiry, S.E. Lawrence, & H.A. Moynihan; (2006) Characterisation of crystalline forms of D-lactose,. [Oral Presentation], Groupement des Pharmacochimistes de l'Arc Atlantique, 15th Conference, University of Bath , 07-SEP-06 - 08-SEP-06. [Details]
(2006)Groupement des Pharmacochimistes de l'Arc Atlantique, 15th Conference,,
Andrea L. Ryan and Humphrey A. Moynihan; (2006) EDTA-conjugates as crystallization-controlling agents. [Oral Presentation], Groupement des Pharmacochimistes de l'Arc Atlantique, 15th Conference,, University of Bath , 07-SEP-06 - 08-SEP-07. [Details]
(2006)2006 All-Ireland Schools of Pharmacy 28th Research Seminar,
K.P. Guiry, H.A. Moynihan & S.E. Lawrence; (2006) Crystallography and crystallization of D-lactose. [Oral Presentation], 2006 All-Ireland Schools of Pharmacy 28th Research Seminar, Queen's University Belfast, School of Pharmacy , 10-APR-06 - 11-APR-06. [Details]
(2006), 2006 All-Ireland Schools of Pharmacy 28th Research Seminar,
A. L. Ryan and H. A. Moynihan; (2006) EDTA-conjugates as crystallization controlling agents. [Oral Presentation], , 2006 All-Ireland Schools of Pharmacy 28th Research Seminar, Queen's University Belfast School of Pharmacy, , 10-APR-06 - 11-APR-06. [Details]
(2006)2006 All-Ireland Schools of Pharmacy 28th Research Seminar,
Caroline A. Blackshields, Jorge Oliveira, Humphrey A. Moynihan and Abina M. Crean; (2006) Alginate-Chitosan Beads: Determining the Influence of Processing Parameters on Bead Formation. [Invited Oral Presentation], 2006 All-Ireland Schools of Pharmacy 28th Research Seminar, Queen's University Belfast School of Pharmacy , 10-APR-06 - 11-APR-06. [Details]
(2006), 2006 All-Ireland Schools of Pharmacy 28th Research Seminar,
Marie McAuliffe and H. A. Moynihan; (2006) The effects of polymeric versus monomeric additives on the nucleation of L-glutamic acid. [Oral Presentation], , 2006 All-Ireland Schools of Pharmacy 28th Research Seminar, Queen's University Belfast School of Pharmacy, , 10-APR-06 - 11-APR-06. [Details]
(2005)Eli Lilly Postgraduate Research Symposium,
J.M. Kelleher, S.E. Lawrence & H.A. Moynihan; (2005) Influence of additives on crystal polymorphism and morphology: probing the effects of hydrogen bonding, conformational mimicry and co-operative binding. [Oral Presentation], Eli Lilly Postgraduate Research Symposium, University College Cork , 15-SEP-05 - 15-SEP-05. [Details]
(2005)XX Congress of the International Union of Crystallography,
J.M. Kelleher, S.E. Lawrence & H.A. Moynihan; (2005) Effect of Additive structure on Crystal Nucleation: Sulfathiazole. [Oral Presentation], XX Congress of the International Union of Crystallography, Florence, Italy , 23-AUG-05 - 31-AUG-05. [Details]
(2005)Crean Schools of Pharmacy Research Seminar,
Caroline A. Blackshields, Ken J. Devine, Humphrey. A. Moynihan, Abina M; (2005) The effect of pH on Levobupivacaine free base solubility and retention on reverse phase HPLC. [Oral Presentation], Crean Schools of Pharmacy Research Seminar, Trinity College Dublin, , 21-MAR-05 - 22-MAR-05. [Details]
(2005)Joint Queen's University Belfast/Trinity College Dublin Pharmacy Research Seminar,
Colman Carroll and Humphrey A. Moynihan; (2005) The preparation of O, S and novel N-linked derivatives of glucuronic acid. [Oral Presentation], Joint Queen's University Belfast/Trinity College Dublin Pharmacy Research Seminar, Trinity College Dublin , 21-MAR-05 - 22-MAR-05. [Details]
(2004)University College Cork/Royal Society of Chemistry Republic of Ireland Section/Analytical Division 3rd Biennial Conference on Analytical Sciences in Ireland,
Wade J. Mace, Emer K. Kelly, Humphrey A. Moynihan, Damien W. M. Arrigan; (2004) Liquid/Liquid Electrochemistry of Calixarene-Based Anion Receptors. [Oral Presentation], University College Cork/Royal Society of Chemistry Republic of Ireland Section/Analytical Division 3rd Biennial Conference on Analytical Sciences in Ireland, University College Cork , 09-SEP-04 - 10-SEP-04. [Details]
(2004)Eli Lilly Postgraduate Research 2nd Annual Symposium in Organic Chemistry,
H. A. Moynihan and P. E. Hanrahan; (2004) Synthesis and stereochemical integrity of 2-arylpropionate thioesters. [Oral Presentation], Eli Lilly Postgraduate Research 2nd Annual Symposium in Organic Chemistry, University College Cork , 07-SEP-04 - 07-SEP-04. [Details]
(2004)RSC Organic Reaction Mechanisms Group/Centre for Synthesis and Chemical Biology: Reaction Mechanisms VII,
P.E. Hanrahan, H.A. Moynihan; (2004) Synthesis and Stereochemical integrity of 2-arylpropionate thioesters and related compounds. [Oral Presentation], RSC Organic Reaction Mechanisms Group/Centre for Synthesis and Chemical Biology: Reaction Mechanisms VII, University College Dublin , 04-JUL-04 - 08-JUL-04. [Details]
(2004)Inaugural Analytical and Biological Chemistry Research Facility Research Day,
J. M. Kelleher, S. E. Lawrence and H. A. Moynihan; (2004) Probing the effects of steric demand and cooperative binding on crystal nucleation. [Oral Presentation], Inaugural Analytical and Biological Chemistry Research Facility Research Day, University College Cork, , 22-APR-04 - 22-APR-04. [Details]
(2004)RSC Organic Reaction Mechanisms Group/Centre for Synthesis and Chemical Biology: Reaction Mechanisms VII,
Wade J. Mace, Emer K. Kelly, Humphrey A. Moynihan, Damien W. M. Arrigan; (2004) Calixarene-Based Anion Receptors for Liquid/Liquid Electrochemistry. [Oral Presentation], RSC Organic Reaction Mechanisms Group/Centre for Synthesis and Chemical Biology: Reaction Mechanisms VII, University College Dublin , 04-JUL-04 - 08-JUL-04. [Details]
(2004)Inaugural Analytical and Biological Chemistry Research Facility Research Day,
H. A. Moynihan and P. E. Hanrahan; (2004) Synthesis and stereochemical integrity of 2-arylpropionate thioesters. [Oral Presentation], Inaugural Analytical and Biological Chemistry Research Facility Research Day, University College Cork , 22-APR-04 - 22-APR-04. [Details]
(2004)Inaugural Analytical and Biological Chemistry Research Facility Research Day,
Colman Carroll and Humphrey A. Moynihan; (2004) Synthesis of 1-amino-D-glucuronic acid and related compounds. [Oral Presentation], Inaugural Analytical and Biological Chemistry Research Facility Research Day, University College Cork , 22-APR-04 - 22-APR-04. [Details]
(2004)Inaugural Analytical and Biological Chemistry Research Facility Research Day,
Wade Mace, Emer K. Kelly, Humphrey A. Moynihan, Damien W. M. Arrigan; (2004) Calixarene-based Anion Receptors for Liquid/Liquid Electrochemistry. [Oral Presentation], Inaugural Analytical and Biological Chemistry Research Facility Research Day, University College Cork, , 22-APR-04 - 22-APR-04. [Details]
(2004)Joint Queen's University Belfast/Trinity College Dublin Pharmacy Research Seminar,
J. M. Kelleher, S. E. Lawrence and H. A. Moynihan; (2004) Probing the effects of steric demand and cooperative binding on pharmaceutical crystal nucleation. [Oral Presentation], Joint Queen's University Belfast/Trinity College Dublin Pharmacy Research Seminar, Queen's University Belfast, , 20-APR-04 - 21-APR-04. [Details]
(2004)Crystallisation of Organic Compounds,
Humphrey A. Moynihan; (2004) Crystallisation of Organic Compounds. [Oral Presentation], Crystallisation of Organic Compounds, Pfizer Pharmaceuticals (Ireland), Ringaskiddy, Cork , 24-SEP-04 - 24-SEP-04. [Details]
(2006)Groupement des Pharmacochimistes de l'Arc Atlantique, 15th Conference,
Humphrey A. Moynihan; (2006) Probing pharmaceutical crystal nucleation at the molecular level. [Oral Presentation], Groupement des Pharmacochimistes de l'Arc Atlantique, 15th Conference, University of Bath , 07-SEP-06 - 08-SEP-06. [Details]
(2008)Synthesis of Bioactive Molecules IV,
Humphrey A. Moynihan; (2008) . [Conference Organising Committee Member], Synthesis of Bioactive Molecules IV, University College Cork , 01-JUL-08 - 01-JUL-08. [Details]
(2007)Synthesis of Bioactive Molecules III,
Humphrey A. Moynihan ; (2007) . [Conference Organising Committee Member], Synthesis of Bioactive Molecules III, University College Cork , 20-APR-07 - 20-APR-07. [Details]
(2005)Synthesis of Bioactive Molecules II,
Humphrey A. Moynihan ; (2005) . [Conference Organising Committee Member], Synthesis of Bioactive Molecules II, University College Cork , 17-FEB-05 - 17-FEB-05. [Details]
(2004)Half-Day Seminar of Organic Chemistry, Royal Society of Chemistry/Analytical and Biological Chemistry Research, Facility, UCC,
Humphrey A. Moynihan ; (2004) . [Conference Organising Committee Member], Half-Day Seminar of Organic Chemistry, Royal Society of Chemistry/Analytical and Biological Chemistry Research, Facility, UCC, University College Cork , 22-APR-04 - 22-APR-04. [Details]
(2003)Analysis of Materials and Bio-materials, Royal Society of Chemistry/UCC Department of Chemistry Half-day Semina,
Humphrey A. Moynihan ; (2003) . [Conference Organising Committee Member], Analysis of Materials and Bio-materials, Royal Society of Chemistry/UCC Department of Chemistry Half-day Semina, University College Cork , 10-SEP-03 - 10-SEP-03. [Details]
(2007)European Federation of Chemical Engineers Working Party on Crystallization, Technical Meeting,
Guiry, K. P.; Coles, S. J.; Lawrence, S. E.; Moynihan, H. A; (2007) Aspects of D-Lactose Crystallization. [Oral Presentation], European Federation of Chemical Engineers Working Party on Crystallization, Technical Meeting, University College Dublin , 23-MAR-07 - 23-MAR-07. [Details]
(1995)Abstracts of European Chemical Society Symposium, Louvain La Neuve, Belgium (August),
Collins, C.; Cronin, M.; O'Flynn, K.; Moynihan, H.; McCarthy, D. G.; (1995) *. [N/A], Abstracts of European Chemical Society Symposium, Louvain La Neuve, Belgium (August), New Routes to Substituted Furanones [B382] , 01-JAN-95 - 30-DEC-99. [Details]

Patents

 Patent NumberTitleInventorGranted
PCT/EP2008/0621Process for the preparation of the alpha crystal polymorph of metal phthalocyanines, Geraldine Claudon and Humphrey Moynihan12-SEP-08

Honours and Awards

 YearTitleAwarding Body
2009Enterprise Ireland Award in recognition of the licensing Enterprise Ireland
2010UCC 1st Annual Research Commercialisation Award UCC

Employment

 EmployerPositionFrom / To
Department of Chemistry,University College Cork Lecturer in Organic Chemistry01-JAN-02 /
Liverpool John Moores University Lecturer in Organic Chemistry01-SEP-94 / 01-DEC-01
University of Bristol Postdoctoral Research Assistant01-OCT-92 / 01-AUG-94
University of Exeter Postdoctoral Research Fellow01-OCT-90 / 01-SEP-92

Education

 YearInstitutionQualificationSubject
1986University College Cork BSc HonsChemistry
1992University College Cork Ph.D.Organic Chemistry

Journal Activities

 JournalRoleTo / From
Carbohydrate Research Referee-
Crystal Engineering Communications Referee-
Journal Of Pharmacy And Pharmacology Referee-
Organic And Medicinal Chemistry Letters Referee-
Crystal Growth And Design Referee-

Teaching Interests

CM3110 Pharmaceutical Solids and Technology: A research inspired module on the pharmaceutical solid state delivered to 3rd year Chemistry of Pharmaceutical Compounds students. 

PF1010 Physicochemical Basis of Pharmaceuticals: An innovative module combining pharmaceutical chemistry and pharmaceutics to present the scientific underpinnings of medicines as materials to Pharmacy students.

CM2002/CM3030 Fundamentals of Organic Chemistry: Teaches core stereochemistry to 2nd year Science students (Chemistry, CPC, Chem Forensics, Biological Sciences and 3rd yr Process Engineers)

CM1006 Introductory Chemistry for Food and Nutritional Scientists: Presents the fundamental of organic chemistry, molecular structure, functional groups,naming and reactions, to 1st year Food and Nutritional Science students. 

CM3102/PF2101 Introduction to Pharmaceutical Chemistry/Pharmaceutical Chemistry 2: Covers the fundamental principles for medicinal chemistry for Chemistry/CPC/CFS/Pharmacy students; including receptors, agonists, antagonists , physicochemical properties, adrenergic ligands and histamine receptor ligands.

CM3022 Synthesis Structure and Reactivity of Organic Compounds: advanced stereochemistry and core oxygen and nitrogen functional group chemistry for 3rd year Chemistry/CPC/CFS students.

Programme Coordinator BSc Chemistry of Pharmaceutical Compounds (CPC): Degree offers all core modules in Chemistry, Biochemistry, Physiology and Pharmacology; with special focus on Organic and Pharmaceutical Chemistry; 5 month industry work placement. Collaboration between the Departments of Chemistry, Biochemistry, Physiology, Pharmacology and the Careers Service. Excellent pharmaceutical industry engagement and strong recruitment. 

Recent Postgraduates

 Graduation YearStudent NameInstitutionDegree TypeThesis Title
2010Andrea L. Ryan UCCPHDPolymorph-selective Crystal Nucleation Control Using Dendritic 'Tailor-made' Additives and Reactive Crystallisations
2012John A. Hayes UCCPHDStudies on the Crystallisation of Organic Compounds (Carbohydrates)
2011Dawn M. Kelly UCCPHDProbing and Controlling Crystal Nucleation and Growth
2009Marie T. McAuliffe UCCPHDDesign and Synthesis of Tailor-made Additives for the Control of Crystal Polymorphism
2011Kevin P. Guiry UCCPHDStudies on the Crystallisation of Lactose and Related Compunds
2014Lorna Lennon UCCPHDCrystallisation and crystal forms of carbohydrate derivatives

Current Postgraduate Students

 StudentDegree Type
Shanahan Louise Marie Doctoral Degree
Horgan Danielle Elizabeth Doctoral Degree
Dennehy Olga Catherine Doctoral Degree

Modules Taught

 Term (ID))TitleLinkSubject
2015Introduction to Pharmaceutical Chemistry CM3102Introduction to Pharmaceutical Chemistry
2015Pharmaceutical Solids and Technology CM3110Pharmaceutical Solids and Technology
2015Physiochemical Basis of Pharmaceuticals PF1010Physiochemical Basis of Pharmaceuticals

Internal Collaborators

 NameInstituteCountry
Dr. Simon E. Lawrence UCCIRELAND
Dr. Abina Crean UCCIRELAND
Prof. A. R. Maguire UCCIRELAND

External Collaborators

 NameOrganisation/ InstitutionCountry
Prof. Damien W. M. Arrigan Curtin Univerisity, Perth, AustraliaIRELAND
Prof. C. J. Rhodes Liverpool John Moores UniversityUNITED KINGDOM
Prof. R. J. Hamilton Liverpool John Moores UniversityUNITED KINGDOM