Research Profile

Aisling Ryan

Biography

A graduate of UCC, Dr. Ryan received her MB, BCh, BAO in 1995. She subsequently trained in general medicine in the Cork University Hospital and allied hospitals before specializing in Neurology. Following a period of specialist neurology training in Dublin, she moved to Germany to undertake a PhD in neuromuscular channelopathies at the Dept of Physiology, University of Ulm.

Dr. Ryan returned to Ireland in 2002 to complete her clinical neurology training. She subsequently spent a year at the Centre for Neuromuscular Disease, National Hospital for Neurology and Neurosurgery, Queen Square, London before returning to a post as Consultant Neurologist in Cork University Hospital. She is also a Senior Clinical Lecturer to undergraduate UCC medical students. 

Dr. Ryan's research Interests are Neurological Channelopathies, Muscle disease, Peripheral Neuropathies, and Multiple Sclerosis. 

Research Grants

 ProjectFunding
Body
Start DateEnd DateAward
HRB"SS-2015-1470 B O'Sullivan"Dr A Ryan ; Summer ScholarshipHealth Research Board13-JUL-1504-SEP-15€2,000.00
Population-based survey of adult neuromuscular disease in the Republic of Ireland.Irish Funded Research Non Exchequer02-JAN-1201-JAN-14€112,000.00

Publications

Peer Reviewed Journals

 YearPublication
(2018)'Chorea-Acanthocytosis and the Huntington Disease Allele in an Irish Family'
Murphy, O. C.,O'Toole, O.,Hand, C. K.,Ryan, A. M. (2018) 'Chorea-Acanthocytosis and the Huntington Disease Allele in an Irish Family'. Tremor and other hyperkinetic movements (New York, N.Y.), 8   [DOI] [Details]
(2018)'Impact of short-term cycle ergometer training on quality of life, cognition and depressive symptomatology in multiple sclerosis patients: a pilot study'
Barry, A.,Cronin, O.,Ryan, A. M.,Sweeney, B.,O’Toole, O.,Allen, A. P.,Clarke, G.,O’Halloran, K. D.,Downer, E. J. (2018) 'Impact of short-term cycle ergometer training on quality of life, cognition and depressive symptomatology in multiple sclerosis patients: a pilot study'. Neurological Sciences, 39 (3):461-469   [DOI] [Details]
(2018)'Familial Hemiplegic Migraine with Asymmetric Encephalopathy Secondary to ATP1A2 Mutation: A Case Series'
Murphy, O. C.,Merwick, A.,O'Mahony, O.,Ryan, A. M.,McNamara, B. (2018) 'Familial Hemiplegic Migraine with Asymmetric Encephalopathy Secondary to ATP1A2 Mutation: A Case Series'. Journal of Clinical Neurophysiology, 35 (1)   [DOI] [Details]
(2017)'A population-based epidemiologic study of adult neuromuscular disease in the Republic of Ireland'
Lefter, S.,Hardiman, O.,Ryan, A. M. (2017) 'A population-based epidemiologic study of adult neuromuscular disease in the Republic of Ireland'. Neurology, 88 (3):304-313   [DOI] [Details]
(2016)'Impact of exercise on innate immunity in multiple sclerosis progression and symptomatology'
Barry, A.,Cronin, O.,Ryan, A. M.,Sweeney, B.,Yap, S. M.,O'Toole, O.,Allen, A. P.,Clarke, G.,O'Halloran, K. D.,Downer, E. J. (2016) 'Impact of exercise on innate immunity in multiple sclerosis progression and symptomatology'. Frontiers in Physiology, 7 (JUN)   [DOI] [Details]
(2015)'A novel MYH7 Leu1453pro mutation resulting in Laing distal myopathy in an Irish family'
Lefter, S.,Hardiman, O.,McLaughlin, R. L.,Murphy, S. M.,Farrell, M.,Ryan, A. M. (2015) 'A novel MYH7 Leu1453pro mutation resulting in Laing distal myopathy in an Irish family'. Neuromuscular Disorders, 25 (2):155-160   [DOI] [Details]
(2014)'The use of cytokine signature patterns: Separating drug naïve, interferon and natalizumab-treated multiple sclerosis patients'
O'Connell, K. E.,Mok, T.,Sweeney, B.,Ryan, A. M.,Dev, K. K. (2014) 'The use of cytokine signature patterns: Separating drug naïve, interferon and natalizumab-treated multiple sclerosis patients'. Autoimmunity, 47 (8):505-511   [DOI] [Details]
(2014)'Methodology and design of a national epidemiological study on adult neuromuscular disease'
Lefter, S.,Hardiman, O.,Ryan, A. M. (2014) 'Methodology and design of a national epidemiological study on adult neuromuscular disease'. Neuroepidemiology, 43 (2):123-130   [DOI] [Details]
(2014)'Andersen-tawil syndrome with early fixed myopathy'
Lefter, S.,Hardiman, O.,Costigan, D.,Lynch, B.,McConville, J.,Hand, C. K.,Ryan, A. M. (2014) 'Andersen-tawil syndrome with early fixed myopathy'. Journal of Clinical Neuromuscular Disease, 16 (2):79-82   [DOI] [Details]
(2011)'VGKC positive autoimmune encephalopathy mimicking dementia'
Molloy, A.,Cassidy, E.,Ryan, A.,O'Toole, O. (2011) 'VGKC positive autoimmune encephalopathy mimicking dementia'. BMJ Case Reports,   [DOI] [Details]
(2011)'Brachial neuritis masquerading as acute coronary syndrome'
Dineen, J.,Saidha, S.,McNamara, B.,Plant, B.,Ryan, A. M. (2011) 'Brachial neuritis masquerading as acute coronary syndrome'. Irish Journal of Medical Science, 180 (1):291-294   [DOI] [Details]
(2011)'Bronchogenic adenocarcinoma presenting as a synchronous solitary lytic skull lesion with ischaemic stroke - Case report and literature review'
O'Connell, D.,Kaliaperumal, C.,Wyse, G.,McCarthy, J.,Ryan, A. (2011) 'Bronchogenic adenocarcinoma presenting as a synchronous solitary lytic skull lesion with ischaemic stroke - Case report and literature review'. BMJ Case Reports,   [DOI] [Details]
(2010)'Alemtuzumab in the treatment of IVIG-dependent chronic inflammatory demyelinating polyneuropathy'
Marsh, E. A.,Hirst, C. L.,Llewelyn, J. G.,Cossburn, M. D.,Reilly, M. M.,Krishnan, A.,Doran, M.,Ryan, A. M.,Coles, A. J.,Jones, J. L.,Robertson, N. P. (2010) 'Alemtuzumab in the treatment of IVIG-dependent chronic inflammatory demyelinating polyneuropathy'. Journal of Neurology, 257 (6):913-919   [DOI] [Details]
(2009)'Vacuolar leucoencephalopathy and pulvinar sign in association with coeliac disease'
Ryan, A. M.,Ryan, J.,Wan-Ahmed, M.,Hardiman, O.,Farrell, M. A.,McNamara, B.,Sweeney, B. J. (2009) 'Vacuolar leucoencephalopathy and pulvinar sign in association with coeliac disease'. BMJ Case Reports,   [DOI] [Details]
(2008)'Simultaneous transverse myelitis and acute motor axonal neuropathy in an adult'
Saidha, S.,Renganathan, R.,Spillane, J.,McNamara, B.,Fanning, N.,Ryan, A. M. (2008) 'Simultaneous transverse myelitis and acute motor axonal neuropathy in an adult'. Journal of Neurology, Neurosurgery and Psychiatry, 79 (11):1302-1303   [DOI] [Details]
(2007)'Skeletal-muscle channelopathies: Periodic paralysis and nondystrophic myotonias'
Ryan, A. M.,Matthews, E.,Hanna, M. G. (2007) 'Skeletal-muscle channelopathies: Periodic paralysis and nondystrophic myotonias'. Current Opinion in Neurology, 20 (5):558-563   [DOI] [Details]
(2007)'Steroid-responsive recurrent encephalopathy in a patient with cerebral amyloid angiopathy'
McHugh, J. C.,Ryan, A. M.,Lynch, T.,Dempsey, E.,Stack, J.,Farrell, M. A.,Kelly, P. J. (2007) 'Steroid-responsive recurrent encephalopathy in a patient with cerebral amyloid angiopathy'. Cerebrovascular Diseases, 23 (1):66-69   [DOI] [Details]
(2007)'Vacuolar leucoencephalopathy and pulvinar sign in association with coeliac disease [1]'
Ryan, A. M.,Ryan, J.,Wan-Ahmed, M.,Hardiman, O.,Farrell, M. A.,McNamara, B.,Sweeney, B. J. (2007) 'Vacuolar leucoencephalopathy and pulvinar sign in association with coeliac disease [1]'. Journal of Neurology, Neurosurgery and Psychiatry, 78 (1):98-99   [DOI] [Details]
(2007)'The phenomenon of disproportionate antecollis in Parkinson's disease and multiple system atrophy'
Van De Warrenburg, B. P. C.,Cordivari, C.,Ryan, A. M.,Phadke, R.,Holton, J. L.,Bhatia, K. P.,Hanna, M. G.,Quinn, N. P. (2007) 'The phenomenon of disproportionate antecollis in Parkinson's disease and multiple system atrophy'. Movement Disorders, 22 (16):2325-2331   [DOI] [Details]
(2006)'Atypical presentation of macrophagic myofasciitis 10 years post vaccination'
Ryan, A. M.,Bermingham, N.,Harrington, H. J.,Keohane, C. (2006) 'Atypical presentation of macrophagic myofasciitis 10 years post vaccination'. Neuromuscul Disord, 16 (1212):867-9867 [Details]
(2006)'A 45-year history of acquired autoimmune neuromyotonia [8]'
Ryan, A.,Mullins, G.,Scott, J.,Connolly, S.,Hardiman, O.,Yilmaz, E.,Vincent, A.,Lynch, T. (2006) 'A 45-year history of acquired autoimmune neuromyotonia [8]'. Journal of Neurology, 253 (9):1243-1245   [DOI] [Details]
(2005)'Vascular dysplasia in neurofibromatosis type 2'
Ryan, A. M.,Hurley, M.,Brennan, P.,Moroney, J. T. (2005) 'Vascular dysplasia in neurofibromatosis type 2'. Neurology, 65 (1):163-164   [DOI] [Details]
(2005)'Fatal toxic leukoencephalopathy: Clinical, radiological, and necropsy findings in two patients'
Ryan, A.,Molloy, F. M.,Farrell, M. A.,Hutchinson, M. (2005) 'Fatal toxic leukoencephalopathy: Clinical, radiological, and necropsy findings in two patients'. Journal of Neurology, Neurosurgery and Psychiatry, 76 (7):1014-1016   [DOI] [Details]
(2003)'Polymyositis masquerading as motor neuron disease'
Ryan, A.,Nor, A. M.,Costigan, D.,Foley-Nolan, D.,El-Rafie, A.,Farrell, M. A.,Hardiman, O. (2003) 'Polymyositis masquerading as motor neuron disease'. Archives of Neurology, 60 (7):1001-1003   [DOI] [Details]
(2002)'Novel CLCN1 mutations with unique clinical and electrophysiological consequences'
Wu, F. F.,Ryan, A.,Devaney, J.,Warnstedt, M.,Korade-Mirnics, Z.,Poser, B.,Escriva, M. J.,Pegoraro, E.,Yee, A. S.,Felice, K. J.,Giuliani, M. J.,Mayer, R. F.,Mongini, T.,Palmucci, L.,Marino, M.,Rüdel, R.,Hoffman, E. P.,Fahlke, C. (2002) 'Novel CLCN1 mutations with unique clinical and electrophysiological consequences'. Brain, 125 (11):2392-2407   [Details]
(2002)'A novel alteration of muscle chloride channel gating in myotonia levior'
Ryan, A.,Rüdel, R.,Kuchenbecker, M.,Fahlke, C. (2002) 'A novel alteration of muscle chloride channel gating in myotonia levior'. Journal of Physiology, 545 (2):345-354   [DOI] [Details]

Contact details

  • Aisling Ryan
    Consultant Neurologist and Senior Clinical Lecturer, CUH and UCC.
  • aisling.ryan4@hse.ie
  • Department of Neurology
    Cork University Hospital
    Wilton, Cork
    Ireland
  • +353 21 49 20138

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