Research Profile

Desmond Murphy

Biography

Consultant Respiratory Physician at Cork University Hospital since June 2009. 
Graduate: Irish Specialist Registrar training program in Respiratory Medicine.
Fellow of Royal College of Physicians of Ireland and the American College of Chest Physicians.
Past recipient of a European Respiratory Society fellowship.
Dr. Murphy attended the Freeman Hospital, Newcastle as a clinical research fellow in lung transplantation.
His research led to the award of a PhD from Newcastle University.
Subsequently, a post doctoral fellow at McMaster University, Canada, where his research and clinical interests were focused on Asthma.
Dr. Murphy is the clinical lead for Asthma, Sleep and Non-invasive Ventilation and Pulmonary Hypertension in CUH.
Other areas of interest include:
Advanced Lung Disease, COPD, Interstitial lung disease, Bronchiectesis and Lung cancer.

Publications

Book Chapters

 YearPublication
(2015)'Pathophysiology of aspiration in the lung'
Chris Ward, Rhys Jones, Mellissa Friel, Eoin Hunt, Des Murphy (2015) 'Pathophysiology of aspiration in the lung' In: Professor Alyn H Morice & Professor Peter Dettmar (eds). Reflux, Aspiration and Lung Disease. UK: Sringer UK. [Details]
(2011)'Inhaled corticosteroids: clinical effects in asthma and COPD'
PM O’Byrne and DM Murphy (2011) 'Inhaled corticosteroids: clinical effects in asthma and COPD' In: Jan Lotvall (eds). Advances in combination therapy for asthma and COPD. West Sussex, UK: Wiley-Blackwell. [Details]

Peer Reviewed Journals

 YearPublication
(2015)'A comparison of standard and novel bronchoscopic endobronchial biopsy retrieval methods'
Khan KA, Ryan C;Burke L;Henry MT;Murphy DM;Plant BJ;O'Connor TM;Curran D;Kennedy MP (2015) 'A comparison of standard and novel bronchoscopic endobronchial biopsy retrieval methods'. Journal of bronchology & interventional pulmonology, 22 (2):130-134 [DOI] [Details]
(2014)'A study to assess inhaler technique and its potential impact on asthma control in patients attending an asthma clinic'
Harnett CM, Hunt EB, Bowen BR, O'Connell OJ, Edgeworth DM, Mitchell P, Eustace JA, Henry MT, Kennedy MP, Plant BJ, Murphy DM (2014) 'A study to assess inhaler technique and its potential impact on asthma control in patients attending an asthma clinic'. The Journal of asthma : official journal of the Association for the Care of Asthma, 51 (4):440-445 [DOI] [Details]
(2014)'Inhaled versus nebulised tobramycin: a real world comparison in adult cystic fibrosis (CF)'
Harrison MJ, McCarthy M, Fleming C, Hickey C, Shortt C, Eustace JA, Murphy DM, Plant BJ (2014) 'Inhaled versus nebulised tobramycin: a real world comparison in adult cystic fibrosis (CF)'. Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society, 13 (6):692-698 [DOI] [Details]
(2014)'T cell-mediated induction of thymic stromal lymphopoietin in differentiated human primary bronchial epithelial cells'
Hui, CCK,Murphy, DM,Neighbour, H,Al-Sayegh, M,O'Byrne, S,Thong, B,Denburg, JA,Larche, M (2014) 'T cell-mediated induction of thymic stromal lymphopoietin in differentiated human primary bronchial epithelial cells'. Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 44 :953-964 [DOI] [Details]
(2013)'A Prospective Study of the CF Gut: Prevalence, Ribotyping and Toxigenic Capability of Clostridium difficile in Adult CF'
Harrison, MJ,Burke, D,Fleming, C,McCarthy, M,Shortt, C,O'Callaghan, G,Murphy, DM,Shanahan, F,Hill, C,Ross, P,Stanton, C,Eustace, JA,Rea, MC,Plant, BJ (2013) 'A Prospective Study of the CF Gut: Prevalence, Ribotyping and Toxigenic Capability of Clostridium difficile in Adult CF'. Irish journal of medical science, 182 :468-468 [Details]
(2013)'Clinical unity and community empowerment: the use of smartphone technology to empower community management of chronic venous ulcers through the support of a tertiary unit'
Quinn, E. M.,Corrigan, M. A.,O'Mullane, J.,Murphy, D.,Lehane, E. A.,Leahy-Warren, P.,Coffey, A.,McCluskey, P.,Redmond, H. P.,Fulton, G. J. (2013) 'Clinical unity and community empowerment: the use of smartphone technology to empower community management of chronic venous ulcers through the support of a tertiary unit'. Plos One, 8 (11)   [Details]

Conference Publications

 YearPublication
(2012)Proceedings of the International Working Conference on Advanced Visual Interfaces
Ma, Ji and Murphy, D and O'Mathuna, C and Hayes, Michael and Provan, Gregory (2012) Visualizing uncertainty in multi-resolution volumetric data using marching cubes Proceedings of the International Working Conference on Advanced Visual Interfaces , pp.489-496 [Details]

Abstract

 YearPublication
(2015)A Study to Evaluate the Safety of Salt Pipe Usage in Asthma.
Wilson, M,Hunt, EB,Bowen, BR,Plant, BJ,Byrne, S,Murphy, DM (2015) A Study to Evaluate the Safety of Salt Pipe Usage in Asthma. Abstract [Details]
(2014)Chronic Kidney Disease with Chronic Obstructive Pulmonary Disease: Decline in Forced Expiratory Volume Correlates with Loss of Glomerular Filtration Rate.
Kelly, DM,Galbraith, EA,Plant, W,Murphy, DM (2014) Chronic Kidney Disease with Chronic Obstructive Pulmonary Disease: Decline in Forced Expiratory Volume Correlates with Loss of Glomerular Filtration Rate. Abstract [Details]
(2013)The investigation of Haemoptysis through a National Cancer Control Program Rapid Access Lung Cancer Clinic.
Bredin, E,Henry, MT,Murphy, DM,Plant, BJ,Ali, K,O'Connell, O,Kennedy, MP (2013) The investigation of Haemoptysis through a National Cancer Control Program Rapid Access Lung Cancer Clinic. Abstract [Details]
(2013)The Prognostic Significance of Hypoglycaemia on Oral Glucose Tolerance Tests in Adults with Cystic Fibrosis (CF): A Prospective Cohort Study.
Neff, KJ,Harrison, MJ,Fleming, C,McCarthy, M,Shortt, C,O'Riordan, SM,Murphy, DM,Plant, BJ,O'Halloran, DJ (2013) The Prognostic Significance of Hypoglycaemia on Oral Glucose Tolerance Tests in Adults with Cystic Fibrosis (CF): A Prospective Cohort Study. Abstract [Details]
(2013)Patient Reported Experience of Pirfenidone use at a Specialist ILD Clinic in Ireland.
O'Connell, OJ,Bowen, B,Murphy, DM,Plant, BJ,Kennedy, MP,Henry, MT (2013) Patient Reported Experience of Pirfenidone use at a Specialist ILD Clinic in Ireland. Abstract [Details]
(2013)Follow-up of Pulmonary Nodules in a Tertiary Referral Centre.
Fitzgerald, DB,O'Connell, O,Houlihan, C,Murphy, DM,Plant, BP,Kennedy, MP,Henry, MT (2013) Follow-up of Pulmonary Nodules in a Tertiary Referral Centre. Abstract [Details]
(2013)Pulmonary Rehabilitation with Psychological Input Further Improves Clinically Relevant Anxiety and Depression in Patients with Stable COPD?.
Bowen, BR,Harrison, MJ,Morgan, TP,Plant, BJ,Kennedy, MP,Murphy, DM,Henry, MT (2013) Pulmonary Rehabilitation with Psychological Input Further Improves Clinically Relevant Anxiety and Depression in Patients with Stable COPD?. Abstract [Details]
(2012)Supporting Lung Cancer Screening: Symptomatic vs Asymptomatic Lung Cancer at Rapid Access Lung Cancer Clinic in the Republic of Ireland.
Stewart, P,Henry, MT,Murphy, DM,Plant, BJ,Pekoz, A,Guiry, S,Kennedy, MP (2012) Supporting Lung Cancer Screening: Symptomatic vs Asymptomatic Lung Cancer at Rapid Access Lung Cancer Clinic in the Republic of Ireland. Abstract [Details]
(2012)Improved Adherence, Tolerability and Low Discontinuation Rate in a Prospective Real World Study with Tobramycin Inhaled Powder (TIP) Compared to Tobramycin Inhaled Solution (TIS) in Cystic Fibrosis (CF).
Harrison, MJ,McCarthy, M,Fleming, C,Hickey, C,Shortt, C,Eustace, JA,Murphy, DM,Plant, BJ (2012) Improved Adherence, Tolerability and Low Discontinuation Rate in a Prospective Real World Study with Tobramycin Inhaled Powder (TIP) Compared to Tobramycin Inhaled Solution (TIS) in Cystic Fibrosis (CF). Abstract [Details]
(2012)Fungal Microbiota in the Adult Cystic Fibrosis (CF) Airway: Characterization by Second-Generation Sequencing and Correlation with Standard Culture-Based Methods and Clinical Phenotype.
Harrison, MJ,Twomey, KB,McCarthy, Y,O'Connell, OJ,Alston, M,Febrer, M,Murphy, DM,Ryan, RP,Plant, BJ (2012) Fungal Microbiota in the Adult Cystic Fibrosis (CF) Airway: Characterization by Second-Generation Sequencing and Correlation with Standard Culture-Based Methods and Clinical Phenotype. Abstract [Details]
(2012)A Study to Assess Inhaler Technique and Level of Asthma Control in Patients with Severe Asthma.
Harnett, C,Bowen, B,Murphy, D,O'Connell, O,Edgeworth, D,Mitchell, P,Plant, B (2012) A Study to Assess Inhaler Technique and Level of Asthma Control in Patients with Severe Asthma. Abstract [Details]
(2012)Ivacaftor Delays Need for Lung Transplant Assessment in a CF Patient Homozygous for the G551D Mutation.
Harrison, MJ,Fleming, C,Khan, KA,McCarthy, M,Shortt, C,Egan, JJ,Murphy, DM,Plant, BJ (2012) Ivacaftor Delays Need for Lung Transplant Assessment in a CF Patient Homozygous for the G551D Mutation. Abstract [Details]
(2012)The Clinical Utility Of A Hand-Held Nasal Nitric Oxide (nNO) Electrochemical Analyser to Screen Patients with Bronchiectasis for Primary Ciliary Dyskinesia (PCD) and Cystic Fibrosis (CF).
Harrison, MJ,Barry, J,Burke, L,Dinneen, S,Murphy, DM,Henry, MT,Plant, BJ,Kennedy, MP (2012) The Clinical Utility Of A Hand-Held Nasal Nitric Oxide (nNO) Electrochemical Analyser to Screen Patients with Bronchiectasis for Primary Ciliary Dyskinesia (PCD) and Cystic Fibrosis (CF). Abstract [Details]
(2012)Gastro-Oesophageal Reflux in a Cohort of Steroid Dependent Asthmatics.
Hunt, EB,Crush, L,Galvin, J,Maher, MM,Murphy, T,Plant, BJ,Murphy, DM (2012) Gastro-Oesophageal Reflux in a Cohort of Steroid Dependent Asthmatics. Abstract [Details]
(2012)THE CLINICAL UTILITY OF A HAND-HELD NASAL NITRIC OXIDE ELECTROCHEMICAL ANALYSER TO SCREEN PATIENTS WITH BRONCHIECTASIS FOR PRIMARY CILIARY DYSKINESIA (PCD) AND CYSTIC FIBROSIS (CF).
Harrison, MJ,Barry, J,Burke, L,Murphy, DM,Henry, MT,Plant, BJ,Kennedy, MP (2012) THE CLINICAL UTILITY OF A HAND-HELD NASAL NITRIC OXIDE ELECTROCHEMICAL ANALYSER TO SCREEN PATIENTS WITH BRONCHIECTASIS FOR PRIMARY CILIARY DYSKINESIA (PCD) AND CYSTIC FIBROSIS (CF). Abstract [Details]
(2012)The Impact of the Implementation of an Ebus-Tbna Program on the Frequency and Diagnostic Yield of Bronchoscopic Biopsy, Brushings, Washings and Lavage.
O'Callaghan, M,McCarthy, J,Burke, L,Henry, MT,Murphy, DM,Plant, BJ,Kennedy, MP (2012) The Impact of the Implementation of an Ebus-Tbna Program on the Frequency and Diagnostic Yield of Bronchoscopic Biopsy, Brushings, Washings and Lavage. Abstract [Details]
(2012)Idiopathic Pulmonary Fibrosis (IPF) and Peri-Nuclear Cytoplasmic Antibody (pANCA) Predating Manifestations of Systemic Vasculitis.
Khan, KA,Harrison, MJ,Fitzgerald, D,Henry, MT,Kennedy, MP,Plant, BJ,Murphy, DM (2012) Idiopathic Pulmonary Fibrosis (IPF) and Peri-Nuclear Cytoplasmic Antibody (pANCA) Predating Manifestations of Systemic Vasculitis. Abstract [Details]
(2011)Pulmonary Sequelae of Severe H1N1 Infection Treated with High Frequency Oscillation: A Case Series.
Edgeworth, DM,Brohan, J,O'Neill, S,Breen, D,Maher, M,Murphy, DM (2011) Pulmonary Sequelae of Severe H1N1 Infection Treated with High Frequency Oscillation: A Case Series. Abstract [Details]
(2011)The Prevalence and Clinical Implications of MRSA Colonisation in Adult Cystic Fibrosis (CF) Patients and their Household Contacts and the Potential Role of Molecular Detection of Colonisation.
Edgeworth, DM,Ho, T,Clancy, L,Fleming, C,Shortt, C,Corcoran, D,Murphy, DM,Plant, BJ (2011) The Prevalence and Clinical Implications of MRSA Colonisation in Adult Cystic Fibrosis (CF) Patients and their Household Contacts and the Potential Role of Molecular Detection of Colonisation. Abstract [Details]
(2011)CT Guided Lung Biopsy at a National Designated Cardiothoracic Lung Cancer Institute.
Kerrigan, J,Kennedy, MP,O'Regan, K,Doyle, D,Maher, M,Plant, BJ,Murphy, DM,Burke, L,Henry, MT (2011) CT Guided Lung Biopsy at a National Designated Cardiothoracic Lung Cancer Institute. Abstract [Details]
(2011)Pulmonary Rehabilitation Improves Clinically Relevant Anxiety and Depression in Patients with Stable COPD.
Bowen, BR,McSwiney, EA,Armstrong, LM,Plant, BJ,Kennedy, MP,Murphy, DM,Henry, MT (2011) Pulmonary Rehabilitation Improves Clinically Relevant Anxiety and Depression in Patients with Stable COPD. Abstract [Details]
(2011)Induction of Thymic Stromal Lymphopoietin (TSLP) in Airway Epithelium by Recombinant Allergens.
Hui, CCK,Murphy, DM,Thong, B,Delespesse, G,Denburg, JA,Larche, M (2011) Induction of Thymic Stromal Lymphopoietin (TSLP) in Airway Epithelium by Recombinant Allergens. Abstract [Details]
(2010)Chronic liver disease and transient liver dysfunction in an Irish Adult Cystic Fibrosis (CF) population.
O'Brien, ME,Ho, T,O'Connell, OJ,Shortt, C,Crosbie, O,Murphy, DM,Plant, BJ (2010) Chronic liver disease and transient liver dysfunction in an Irish Adult Cystic Fibrosis (CF) population. Abstract [Details]
(2010)A new diagnosis of classic cystic fibrosis in a 76-year old female: implications of late diagnosis.
O'Brien, ME,Shortt, C,Fleming, C,Murphy, DM,Plant, BJ (2010) A new diagnosis of classic cystic fibrosis in a 76-year old female: implications of late diagnosis. Abstract [Details]
(2010)Reproductive and sexual health (RSH) in Irish males with cystic fibrosis (CF): attitudes and awareness. A prospective study.
Power, RF,O'Connell, OJ,O'Brien, ME,Shortt, C,Fleming, C,Murphy, DM,Plant, BJ (2010) Reproductive and sexual health (RSH) in Irish males with cystic fibrosis (CF): attitudes and awareness. A prospective study. Abstract [Details]
(2010)Cystic fibrosis genetics: what does the patient know?.
Power, RF,O'Connell, OJ,O'Brien, ME,Shortt, C,Fleming, C,Murphy, DM,Plant, BJ (2010) Cystic fibrosis genetics: what does the patient know?. Abstract [Details]
(2010)Progress in lung cancer care: enhanced referral, diagnostic pathways and surgical resection rates through the sustained development thoracic oncology multidisciplinary team (MDT).
O'Brien, ME,O'Cathail, SM,O'Dea, P,Hinchion, J,Plant, BJ,Murphy, DM,Kennedy, MP,O'Connor, TM,Henry, MT (2010) Progress in lung cancer care: enhanced referral, diagnostic pathways and surgical resection rates through the sustained development thoracic oncology multidisciplinary team (MDT). Abstract [Details]

Book Reviews

 YearPublication
(2010)Macrolide antibiotics and the airway: antibiotic or non-antibiotic effects?.
Murphy, DM,Forrest, IA,Curran, D,Ward, C (2010) Macrolide antibiotics and the airway: antibiotic or non-antibiotic effects?. Book Reviews [DOI] [Details]

Other

 YearPublication
(2013)Peri-Lung Transplant Renal Issues in Patients With Cystic Fibrosis.
O'Connell, OJ,Harrison, MJ,Murphy, DM,Plant, WD,Plant, BJ (2013) Peri-Lung Transplant Renal Issues in Patients With Cystic Fibrosis. Other [DOI] [Details]
(2010)Relief of Chronic Neuropathic Pain through Endothelin Antagonism.
Murphy, DM,O'Callaghan, DS,Gaine, SP (2010) Relief of Chronic Neuropathic Pain through Endothelin Antagonism. Other [DOI] [Details]
(2006)The Optimum Power Conversion Efficiency and Associated Gain of An Lc Cmos Oscillator.
Murphy, D, Kennedy, MP, Buckley, J, Qu, M; (2006) The Optimum Power Conversion Efficiency and Associated Gain of An Lc Cmos Oscillator. Other [Details]
(2005)Observations On The Relationship Between Energy Transfer Efficiency and Phase Noise In An Lc Oscillator.
Murphy, D, Qu, M, Buckley, J, Kennedy, MP; (2005) Observations On The Relationship Between Energy Transfer Efficiency and Phase Noise In An Lc Oscillator. Other [Details]

Published abstracts

 YearPublication
(2015)The role of PGE2 in cystic fibrosis (CF) lung inflammation and the potential association with ivacaftor therapy and treatment response.
4. O'Callaghan G, Ronan NJ, Foley N, Lyons C, O'Driscoll A, Ni Chroinin M, Mullane D, Murphy D, Shanahan F, Eustace JA, Houston A and Plant BJ (2015) The role of PGE2 in cystic fibrosis (CF) lung inflammation and the potential association with ivacaftor therapy and treatment response. Published abstracts [Details]

Published Letters

 YearPublication
(2013)Ivacaftor in a G551D Homozygote with Cystic Fibrosis.
Harrison, MJ,Murphy, DM,Plant, BJ (2013) Ivacaftor in a G551D Homozygote with Cystic Fibrosis. Published Letters [Details]

Reviews

 YearPublication
(2010)Macrolide antibiotics and the airway: antibiotic or non-antibiotic effects?.
Murphy, DM;Forrest, IA;Curran, D;Ward, C (2010) Macrolide antibiotics and the airway: antibiotic or non-antibiotic effects?. LONDON: Reviews [DOI] [Details]

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School of Biological, Earth and Environmental Sciences

An Scoil Eolaíochtaí Bitheolaíocha, Domhaneolaíocha agus Comhshaoil

University College Cork, Distillery Fields, North Mall, Cork, Ireland T23 N73K

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