Research Profile

Yvonne O'Callaghan

Biography

Research Interests

Publications

Peer Reviewed Journals

 YearPublication
(2014)'Involvement of oxysterols in age-related diseases and ageing processes'
Zarrouk, A; Vejux, A; Mackrill, J; O'Callaghan, Y; Hammami, M; O'Brien, N; and Lizard, G. (2014) 'Involvement of oxysterols in age-related diseases and ageing processes'. Ageing Research Reviews,   [DOI] [Details]
(2014)'In vitro investigation of the bioaccessibility of carotenoids from raw, frozen and boiled red chili peppers (Capsicum annuum)'
Pugliese, A,O'Callaghan, Y,Tundis, R,Galvin, K,Menichini, F,O'Brien, N,Loizzo, MR (2014) 'In vitro investigation of the bioaccessibility of carotenoids from raw, frozen and boiled red chili peppers (Capsicum annuum)'. European Journal of Nutrition, 53 :501-510 [DOI] [Details]
(2014)'An examination of the potential of seaweed extracts as functional ingredients in milk'
O'Sullivan, AM,O'Callaghan, YC,O'Grady, MN,Waldron, DS,Smyth, TJ,O'Brien, NM,Kerry, JP (2014) 'An examination of the potential of seaweed extracts as functional ingredients in milk'. International Journal of Dairy Technology, 67 :182-193 [DOI] [Details]
(2014)'In vitro Assessment of the Bioaccessibility of Carotenoids from Sun-Dried Chilli Peppers'
Pugliese, A,O'Callaghan, Y,Tundis, R,Galvin, K,Menichini, F,O'Brien, N,Loizzo, MR (2014) 'In vitro Assessment of the Bioaccessibility of Carotenoids from Sun-Dried Chilli Peppers'. Plant Foods For Human Nutrition, 69 :8-17 [DOI] [Details]
(2013)'Characterisation of the physicochemical, residual antigenicity and cell activity properties of transglutaminase cross-linked sodium caseinate hydrolysates'
O'Sullivan, D,Lahart, N,O'Callaghan, Y,O'Brien, NM,FitzGerald, RJ (2013) 'Characterisation of the physicochemical, residual antigenicity and cell activity properties of transglutaminase cross-linked sodium caseinate hydrolysates'. International Dairy Journal, 33 :49-54 [DOI] [Details]
(2013)'Synthesis and assessment of the relative toxicity of the oxidised derivatives of campesterol and dihydrobrassicasterol in U937 and HepG2 cells'
O'Callaghan Y, Kenny O, O'Connell NM, Maguire AR, McCarthy FO, O'Brien NM (2013) 'Synthesis and assessment of the relative toxicity of the oxidised derivatives of campesterol and dihydrobrassicasterol in U937 and HepG2 cells'. Biochimie, :496-503 [DOI] [Details]
(2013)'Comparison of the antioxidant activity of commercial honeys before and after in vitro digestion'
O'Sullivan, A.M., O'Callaghan, Y.C., O'Connor, T.P. and O'Brien, N.M. (2013) 'Comparison of the antioxidant activity of commercial honeys before and after in vitro digestion'. Polish Journal Of Food And Nutrition Sciences, 63 :167-171 [Details]
(2013)'The effect of domestic processing on the content and bioaccessibility of carotenoids from chili peppers (Capsicum species)'
Pugliese, A,Loizzo, MR,Tundis, R,O'Callaghan, Y,Galvin, K,Menichini, F,O'Brien, N (2013) 'The effect of domestic processing on the content and bioaccessibility of carotenoids from chili peppers (Capsicum species)'. Food Chemistry, 141 :2606-2613 [DOI] [Details]
(2013)'The effect of solvents on the antioxidant activity in Caco-2 cells of Irish brown seaweed extracts prepared using accelerated solvent extraction (ASE®)'
O’Sullivan, A.M., O’Callaghan, Y.C., O’Grady, M.N., Hayes, M., Kerry, J.P. and O’Brien, N.M. (2013) 'The effect of solvents on the antioxidant activity in Caco-2 cells of Irish brown seaweed extracts prepared using accelerated solvent extraction (ASE®)'. Journal Of Functional Foods, 5 :940-948 [Details]
(2012)'Oxidized Derivatives of Dihydrobrassicasterol: Cytotoxic and Apoptotic Potential in U937 and HepG2 Cells'
Kenny, O,O'Callaghan, Y,O'Connell, NM,McCarthy, FO,Maguire, AR,O'Brien, NM (2012) 'Oxidized Derivatives of Dihydrobrassicasterol: Cytotoxic and Apoptotic Potential in U937 and HepG2 Cells'. Journal of Agricultural and Food Chemistry, 60 :5952-5961 [DOI] [Details]
(2012)'Assessment of the ability of seaweed extracts to protect against hydrogen peroxide and tert-butyl hydroperoxide induced cellular damage in Caco-2 cells'
O’Sullivan, A.M., O’Callaghan, Y.C., O’Grady, M.N., Queguineur, B., Hanniffy, D., Troy, D.J., Kerry, J.P. and O’Brien, N.M. (2012) 'Assessment of the ability of seaweed extracts to protect against hydrogen peroxide and tert-butyl hydroperoxide induced cellular damage in Caco-2 cells'. Food Chemistry, 134 :1137-1140 [Details]
(2011)'In vitro and cellular antioxidant activities of seaweed extracts prepared from five brown seaweeds harvested in spring from the west coast of Ireland'
O'Sullivan, A. M. and O'Callaghan, Y. C. and O'Grady, M. N. and Queguineur, B. and Hanniffy, D. and Troy, D. J. and Kerry, J. P. and O'Brien, N. M. (2011) 'In vitro and cellular antioxidant activities of seaweed extracts prepared from five brown seaweeds harvested in spring from the west coast of Ireland'. Food Chemistry, 126 (3):1064-1070 [Details]
(2010)'Bioaccessibility, cellular uptake and transepithelial transport of alpha-tocopherol and retinol from a range of supplemented foodstuffs assessed using the caco-2 cell model'
O'Callaghan, Y,O'Brien, N; (2010) 'Bioaccessibility, cellular uptake and transepithelial transport of alpha-tocopherol and retinol from a range of supplemented foodstuffs assessed using the caco-2 cell model'. International Journal of Food Science and Technology, 45 :1436-1442 [DOI] [Details]
(2010)'Synthesis and characterisation of stigmasterol oxidation products'
Foley, DA; O'Callaghan, Y; O'Brien, NM; McCarthy, FO; Maguire, AR; (2010) 'Synthesis and characterisation of stigmasterol oxidation products'. Journal of Agricultural and Food Chemistry, 58 :1165-1173 [Details]
(2010)'Cytotoxic and apoptotic effects of the oxidized derivatives of stigmasterol in the U937 human monocytic cell line'
O'Callaghan, Y. C.,Foley, D. A.,O'Connell, N. M.,McCarthy, F. O.,Maguire, A. R.,O'Brien, N. M.; (2010) 'Cytotoxic and apoptotic effects of the oxidized derivatives of stigmasterol in the U937 human monocytic cell line'. J Agric Food Chem, 58 (1919):10793-810793   [Details]
(2008)'Effects of ingredient incorporation into sausage meat on the micellarisation and uptake of alpha-tocopherol by Caco-2 human intestinal cells'
Kenny, O. and O'Callaghan, Y. and O'Brien, N. M. (2008) 'Effects of ingredient incorporation into sausage meat on the micellarisation and uptake of alpha-tocopherol by Caco-2 human intestinal cells'. Food Science and Technology International, 14 (1):79-86 [Details]
(2007)'The bioaccessibility of alpha-tocopherol and retinol from a range of vitamin-enriched foods'
O'Callaghan, Y. C. and Kenny, O. and O'Brien, N. M.; (2007) 'The bioaccessibility of alpha-tocopherol and retinol from a range of vitamin-enriched foods'. PROCEEDINGS OF THE NUTRITION SOCIETY, 66 (Sp. Iss. SI) [Details]
(2007)'Evaluation of the antioxidant potential of grape seed and bearberry extracts in raw and cooked pork'
Carpenter, R. and O'Grady, M. N. and O'Callaghan, Y. C. and O'Brien, N. M. and Kerry, J. P. (2007) 'Evaluation of the antioxidant potential of grape seed and bearberry extracts in raw and cooked pork'. Meat Science, 76 (4):604-610 [Details]
(2006)'Modulatory effects of resveratrol, citroflavan-3-ol and plant derived extracts on oxidative stress in U937 cells'
Carpenter, R, O’Callaghan, Y.C., O’Grady, M., Kerry, J.P. and O’Brien, N.M. (2006) 'Modulatory effects of resveratrol, citroflavan-3-ol and plant derived extracts on oxidative stress in U937 cells'. Journal Of Medicinal Food, 9 :187-195 [Details]
(2006)'Assessment of the micellarisation of alpha-tocopherol from processed meat products using an in vitro model'
Kenny, O. and O'Callaghan, Y. C. and O'Brien, N. M.; (2006) 'Assessment of the micellarisation of alpha-tocopherol from processed meat products using an in vitro model'. PROCEEDINGS OF THE NUTRITION SOCIETY, 65 (Suppl. S) [Details]
(2006)'Involvement of calcium in 7 beta-hydroxycholesterol and cholesterol-5 beta,6 beta-epoxide-induced apoptosis'
Ryan, L. and O'Callaghan, Y. C. and O'Brien, N. M. (2006) 'Involvement of calcium in 7 beta-hydroxycholesterol and cholesterol-5 beta,6 beta-epoxide-induced apoptosis'. International Journal of Toxicology, 25 (1):35-39 [Details]
(2005)'Oxidised products of cholesterol: Their role in apoptosis'
Ryan, L., O'Callaghan, Y.C. and O'Brien, N.M.; (2005) 'Oxidised products of cholesterol: Their role in apoptosis'. 1 (*):41-51 [Details]
(2005)'Modulatory effects of resveratol, citroflavan-3-ol and plant-derived extracts oil oxidative stress in U937 cells'
Carpenter, R. and O'Callaghan, Y. C. and O'Grady, M. and Kerry, J. P. and O'Brien, N. M.; (2005) 'Modulatory effects of resveratol, citroflavan-3-ol and plant-derived extracts oil oxidative stress in U937 cells'. PROCEEDINGS OF THE NUTRITION SOCIETY, 64 (Suppl. S) [Details]
(2005)'The role of the mitochondria in apoptosis induced by cholesterol-5b,6b-epoxide and 7b-hydroxycholesterol'
Ryan, L., O'Callaghan, Y.C. and O'Brien, N.M.; (2005) 'The role of the mitochondria in apoptosis induced by cholesterol-5b,6b-epoxide and 7b-hydroxycholesterol'. British Journal of Nutrition, 94 (*):519-525 [Details]
(2005)'Differential effects of mixtures of cholesterol oxidation products on bovine aortic endothelial cells and human monocytic U937 cells'
O'Sullivan, A. J. and O'Callaghan, Y. C. and O'Brien, N. M. (2005) 'Differential effects of mixtures of cholesterol oxidation products on bovine aortic endothelial cells and human monocytic U937 cells'. International Journal of Toxicology, 24 (3):173-179 [Details]
(2004)'Phytosterols: lack of cytotoxicity but interference with beta-carotene uptake in Caco-2 cells in culture'
Fahy, D. M. and O'Callaghan, Y. C. and O'Brien, N. M. (2004) 'Phytosterols: lack of cytotoxicity but interference with beta-carotene uptake in Caco-2 cells in culture'. Food Additives and Contaminants, 21 (1):42-51 [Details]
(2004)'Generation of an oxidative stress precedes caspase activation during 7 beta-hydroxycholesterol-induced apoptosis in U937 cells'
Ryan, L. and O'Callaghan, Y. C. and O'Brien, N. M. (2004) 'Generation of an oxidative stress precedes caspase activation during 7 beta-hydroxycholesterol-induced apoptosis in U937 cells'. Journal of Biochemical and Molecular Toxicology, 18 (1):50-59 [Details]
(2004)'Comparison of the apoptotic processes induced by the oxysterols 7 beta-hydroxycholesterol and cholesterol-5 beta,6 beta-epoxide'
Ryan, L,O'Callaghan, YC,O'Brien, NM; (2004) 'Comparison of the apoptotic processes induced by the oxysterols 7 beta-hydroxycholesterol and cholesterol-5 beta,6 beta-epoxide'. Cell Biology and Toxicology, 20 :313-323 [Details]
(2004)'The effect of beta-carotene in combination with tocopherols in protecting human fibroblast cells against UVA-induced DNA damage'
O'Callaghan, Y.C. and O'Brien, N.M.; (2004) 'The effect of beta-carotene in combination with tocopherols in protecting human fibroblast cells against UVA-induced DNA damage'. Journal of Dermatological Sciences, 34 (*):231-233 [Details]
(2004)'Comparison of the apoptotic processes induced by the oxysterols 7b-hydroxycholesterol and cholesterol-5b,6b-epoxide'
Ryan, L., O'Callaghan, Y.C. and O'Brien, N.M.; (2004) 'Comparison of the apoptotic processes induced by the oxysterols 7b-hydroxycholesterol and cholesterol-5b,6b-epoxide'. Cell Biology and Toxicology, 20 (*):313-323 [Details]
(2003)'Toxicity of cholesterol oxidation products to Caco-2 and HepG2 cells: Modulatory effects of alpha- and gamma-tocopherol'
O'Sullivan, A. J. and O'Callaghan, Y. C. and Woods, J. A. and O'Brien, N. M. (2003) 'Toxicity of cholesterol oxidation products to Caco-2 and HepG2 cells: Modulatory effects of alpha- and gamma-tocopherol'. Journal of Applied Toxicology, 23 (3):191-197 [Details]
(2002)'Characteristics of 7 beta-hydroxycholesterol-induced cell death in a human monocytic blood cell line, U937, and a human hepatoma cell line, HepG2'
O'Callaghan, Y. C. and Woods, J. A. and O'Brien, N. M. (2002) 'Characteristics of 7 beta-hydroxycholesterol-induced cell death in a human monocytic blood cell line, U937, and a human hepatoma cell line, HepG2'. Toxicology in Vitro, 16 (3):245-251 [Details]
(2001)'Comparative study of the cytotoxicity and apoptosis-inducing potential of commonly occurring oxysterols'
O'Callaghan, YC,Woods, JA,O'Brien, NM; (2001) 'Comparative study of the cytotoxicity and apoptosis-inducing potential of commonly occurring oxysterols'. Cell Biology and Toxicology, 17 :127-137 [Details]
(2001)'Limitations of the single-cell gel electrophoresis assay to monitor apoptosis in U937 and HepG2 cells exposed to 7 beta-hydroxycholesterol'
O'Callaghan, Y. C. and Woods, J. A. and O'Brien, N. M. (2001) 'Limitations of the single-cell gel electrophoresis assay to monitor apoptosis in U937 and HepG2 cells exposed to 7 beta-hydroxycholesterol'. Biochemical Pharmacology, 61 (10):1217-1226 [Details]
(2000)'Biological effects of dietary cholesterol oxidation products'
O'Brien, N.M., Woods, J.A., Lyons, N.M. and O'Callaghan, Y.C.; (2000) 'Biological effects of dietary cholesterol oxidation products'. Irish Journal of Agricultural and Food Research, 39 (*):265-273 [Details]
(2000)'Cytotoxicity, genotoxicity and oxidative reactions in cell-culture models: modulatory effects of phytochemicals'
O'Brien, N. M. and Woods, J. A. and Aherne, S. A. and O'Callaghan, Y. C. (2000) 'Cytotoxicity, genotoxicity and oxidative reactions in cell-culture models: modulatory effects of phytochemicals'. Biochemical Society Transactions, 28 :22-26 [Details]
(1999)'Oxysterol-induced cell death in U937 and HepG2 cells at reduced and normal serum concentrations'
O'Callaghan, Y. C. and Woods, J. A. and O'Brien, N. M. (1999) 'Oxysterol-induced cell death in U937 and HepG2 cells at reduced and normal serum concentrations'. European Journal of Nutrition, 38 (6):255-262 [Details]

Conference Publications

 YearPublication
(2005)51st International Congress of Meat Science and Technology
Carpenter, R., O’Grady, M.N., O’Callaghan, Y.C., O’Brien, N.M. and Kerry, J.P.; (2005) Assessment of health promoting plant derived neutraceuticals as potential antioxidants for use in meat systems . In: * eds. 51st International Congress of Meat Science and Technology Baltimore, Maryland, USA, , 08-AUG-05 - 13-AUG-05 , pp.258-* [Details]

Other

 YearPublication
(2004)The effect of carotenoids and tocopherols in the protection of human fibroblast cells against UVA-induced DNA damage.
O'Callaghan, Y,O'Brien, N (2004) The effect of carotenoids and tocopherols in the protection of human fibroblast cells against UVA-induced DNA damage. Other [DOI] [Details]

Reviews

 YearPublication
(2014)Recent advances in Phytosterol Oxidation Products.
O'Callaghan, Y,McCarthy, FO,O'Brien, NM (2014) Recent advances in Phytosterol Oxidation Products. Reviews [DOI] [Details]

Professional Activities

Conference Contributions

 YearPublication
(2007)Nutrition Society Meeting,
O'Callaghan Y, Kenny O, O'Brien NM.; (2007) The bioaccessibility of -tocopherol and retinol from a range of vitamin-enriched foods. [Oral Presentation], Nutrition Society Meeting, Coleraine , 01-JUN-07 - 01-JUN-07. [Details]
(2006)Nutrition Society Meeting,
Kenny, O., O'Callaghan, Y.C. and O'Brien, N.M.; (2006) Assessment of the micellarisation of $-tocopherol from processed meat products using an in-vitro model. [Oral Presentation], Nutrition Society Meeting, Aberdeen, Scotland , 01-JUL-06 - 01-JUL-06. [Details]
(2006)Nutrition Society Meeting,
Lordan, S., O'Callaghan, Y.C. and O'Brien, N.M. (2006) OxLDL- and oxysterol-induced cell death in U937 and HL-60 blood cells. [Oral Presentation], Nutrition Society Meeting, Aberdeen, Scotland , 01-JUL-06 - 01-JUL-06. [Details]
(2005)Nutrition Society Meeting-Irish Section,
Carpenter, R., O'Callaghan, Y.C., Kerry, J and van Pelt, F.; (2005) Modulatory effects of resveratrol, citroflavan-3-ol and plant derived extracts on oxidative stress in U937 cells. [Oral Presentation], Nutrition Society Meeting-Irish Section, Belfast, Ireland , 15-JUN-05 - 17-JUN-05. [Details]
(2005)35th Annual Food Science and Technology Research Conference,
Carpenter, R., O'Callaghan, Y.C., O'Grady, M.N., Kerry, J.P. and O'Brien, N.M.; (2005) Antioxidant effect of health promoting plant derived neutraceuticals for use in meat systems. [Poster Presentation], 35th Annual Food Science and Technology Research Conference, Cork, Ireland , 01-SEP-05 - 02-SEP-05. [Details]
(2005)35th Annual Food Science and Technology Research Conference,
Carpenter, R., O’Grady, M.N., O’Callaghan, Y.C., O’Brien, N.M. and Kerry, J.P.; (2005) Health promoting plant derived neutraceuticals for use in meat systems. [Oral Presentation], 35th Annual Food Science and Technology Research Conference, UCC,Cork , 01-SEP-05 - 02-SEP-05. [Details]
(2005)13th Annual Research Day (Faculty of Medicine and Health, UCC),
carpenter, R., O'Callaghan, Y.C., O'Grady, N.M., Kerry, J.P. and O'Brien, N.M.; (2005) Evaluation of antioxidant activity of plant extracts. [Poster Presentation], 13th Annual Research Day (Faculty of Medicine and Health, UCC), Cork, Ireland , 22-JUN-05 - 22-JUN-05. [Details]
(2004)12th Annual Research Day, Faculty of Medicine and Health,
Ryan, L., O'Callaghan, Y.C. and O'Brien, N.M.; (2004) Investigation of the pathway of apoptosis induced by 7beta-hydroxycholesterol and cholesterol-5beta,6beta-epoxide in U937 cells. [Poster Presentation], 12th Annual Research Day, Faculty of Medicine and Health, Cork, Ireland , 09-JUN-04 - 09-JUN-04. [Details]
(2005)13th Annual Faculty of Medicine and Health Research Day,
Carpenter, R., O’Callaghan, Y.C., O’Grady, M.N., Kerry, J.P. and O’Brien, N.M.; (2005) Evaluation of antioxidant activity of plant extracts. [Oral Presentation], 13th Annual Faculty of Medicine and Health Research Day, Cork University Hospital , 22-JUN-05 - 22-JUN-05. [Details]
(2004)Nutrition Society Meeting - Irish Section,
Ryan, L., O'Callaghan, Y.C. and O'Brien, N.M.; (2004) The effect of antioxidants and inhibitors of apoptosis on cholesterol 5b,6b-epoxide-induced cell death in U937 cells. [Oral Presentation], Nutrition Society Meeting - Irish Section, Dublin, Ireland , 06-JUL-04 - 09-JUL-04. [Details]
(2004)Nutrition Society Meeting - Irish Section,
O'Callaghan, Y.C. and O'Brien, N.M.; (2004) Immunomodulatory effects of b-sitosterl and b-sitosterol-oxides. [Poster Presentation], Nutrition Society Meeting - Irish Section, Dublin, Ireland , 06-JUL-04 - 09-JUL-04. [Details]
(1999)51st International Congress of Meat Science and Technology,
Carpenter, R., O'Callaghan, Y.C., O'Grady, N.M., Kerry, J.P. and O'Brien, N.M.; (1999) Assessment of plant derived neutraceuticals with potential antioxidant properties for use in meat systems and the enhancement of health. [Poster Presentation], 51st International Congress of Meat Science and Technology, Baltimore, Maryland, USA , 30-DEC-99 - 30-DEC-99. [Details]
(2004)Nutrition society meeting-Irish section,
Ryan, L., O'Callaghan, Y.C. and O'Brien, N.M.; (2004) The role of the mitochondria in apoptosis induced bt cholesterol 5beta, 6beta-epoxide and 7beta-hydroxycholesterol. [Oral Presentation], Nutrition society meeting-Irish section, Dublin, Ireland , 06-JUL-04 - 09-JUL-04. [Details]

Contact details

  • Yvonne O'Callaghan
    Research Support Officier
  • y.ocallaghan@ucc.ie
  • School of Food & Nutritional Sciences
    Room 109A
    Food Science Building
    University College Cork
  • 00353-21-4902846

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School of Biological, Earth and Environmental Sciences

An Scoil Eolaíochtaí Bitheolaíocha, Domhaneolaíocha agus Comhshaoil

University College Cork, Distillery Fields, North Mall, Cork, Ireland T23 N73K

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