Research Profile

Pauline Scanlan

Biography

Pauline Scanlan graduated in 2002 with a B.Sc. in Plant and Microbiology Biotechnology (1H) from University College Cork (UCC). She continued her education at UCC and graduated with a Ph.D. in Medicine in 2007; this included a one-year Marie Curie studentship at Wageningen University, The Netherlands. Shortly afterwards she moved to the Department of Zoology at the University of Oxford, U.K. as a postdoctoral researcher in the lab of Prof. Angus Buckling. Dr Scanlan returned to Ireland in 2012 and following a short postdoctoral research position at UCC she moved to Teagasc, Moorepark after successfully securing a Marie Curie Intra-European Research Fellowship. In 2015, Dr Scanlan was one of the first awardees of the prestigious Royal Society-Science Foundation Ireland University Research Fellowship and moved to the APC Microbiome Institute at UCC to take up the position. Pauline was appointed as a lecturer at the School of Microbiology in 2017.

Research Interests

• Ecology and evolution of the gut microbiome
• Prevalence, diversity and function of gut microbial eukarya (Fungi and Protists e.g. Blastocystis)
• Bacteriophages
• Host-parasite coevolution
• Chronic Disease
My main research interests centre on the ecology and evolution of the human gut microbiome. I am interested in understanding how inter-specific interactions between microbes at different scales and in response to different abiotic factors affect the diversity, structure and function of the gut microbiome, and ultimately host health. To address these research questions I am developing in vitro and in vivo model systems to study the ecology and evolution of the gut microbiome and complementing this approach by studying naturally occurring communities of gut microbes. I am also interested in better understanding the global prevalence, diversity, and role of specific microbes such as Blastocystis and fungi in human health and disease.
https://scholar.google.com/citations?user=iOCYO2sAAAAJ&hl=en

Research Grants

 ProjectFunding
Body
Start DateEnd DateAward
Gut Microbiome Evolution: Implications for Microbial Diversity and Functuality and Host Health.Enterprise Irl18-AUG-1718-MAY-18€7,994.00

Publications

Peer Reviewed Journals

 YearPublication
(2016)'Prevalence and genetic diversity of Blastocystis in family units living in the United States'
Scanlan, Pauline D.; Knight, Rob; Song, Se Jin; Ackermann, Gail; Cotter, Paul D. (2016) 'Prevalence and genetic diversity of Blastocystis in family units living in the United States'. Infection Genetics And Evolution, 45 :95-97   [DOI] [CORA Link] [Details]
(2009)'Culture-independent analysis of desulfovibrios in the human distal colon of healthy, colorectal cancer and polypectomized individuals'
Scanlan, Pauline D. and Shanahan, Fergus and Marchesi, Julian R. (2009) 'Culture-independent analysis of desulfovibrios in the human distal colon of healthy, colorectal cancer and polypectomized individuals'. Fems Microbiology Ecology, 69 (2):213-221 [Details]
(2008)'Culture-independent analysis of the gut microbiota in colorectal cancer and polyposis'
Scanlan, PD,Shanahan, F,Clune, Y,Collins, JK,O'Sullivan, GC,O'Riordan, M,Holmes, E,Wang, YL,Marchesi, JR; (2008) 'Culture-independent analysis of the gut microbiota in colorectal cancer and polyposis'. Environmental Microbiology, 10 (3):789-798 [DOI] [Details]
(2008)'Culture-independent analysis of the gut microbiota in colorectal cancer and polyposis (vol 10, pg 789, 2008)'
Scanlan, P. D.,Shanahan, F.,Clune, Y.,Collins, J. K.,O'Sullivan, G. C.,O'Riordan, M.,Holmes, E.,Wang, Y. L.,Marchesi, J. R. (2008) 'Culture-independent analysis of the gut microbiota in colorectal cancer and polyposis (vol 10, pg 789, 2008)'. Environ Microbiol, 10 (55):1382-13821382   [Details]
(2008)'Human methanogen diversity and incidence in healthy and diseased colonic groups using mcrA gene analysis'
Scanlan, P. D.,Shanahan, F.,Marchesi, J. R. (2008) 'Human methanogen diversity and incidence in healthy and diseased colonic groups using mcrA gene analysis'. BMC Microbiology, 8   [Details]
(2007)'Rapid and noninvasive metabonomic characterization of inflammatory bowel disease'
Marchesi, J. R.,Holmes, E.,Khan, F.,Kochhar, S.,Scanlan, P.,Shanahan, F.,Wilson, I. D.,Wang, Y. L. (2007) 'Rapid and noninvasive metabonomic characterization of inflammatory bowel disease'. Journal of Proteome Research, 6 (2):546-551   [Details]
(2007)'Rapid and noninvasive metabonomic characterization of inflammatory bowel disease'
Marchesi, JR,Holmes, E,Khan, F,Kochhar, S,Scanlan, P,Shanahan, F,Wilson, ID,Wang, YL (2007) 'Rapid and noninvasive metabonomic characterization of inflammatory bowel disease'. Journal of Proteome Research, 6 :546-551 [DOI] [Details]
(2007)'Culture-independent analyses of temporal variation of the dominant fecal microbiota and targeted bacterial subgroups in Crohn's disease (vol 44, pg 3980, 2006)'
Scanlan, P. D.,Shanahan, F.,O'Mahony, C.,Marchesi, J. R. (2007) 'Culture-independent analyses of temporal variation of the dominant fecal microbiota and targeted bacterial subgroups in Crohn's disease (vol 44, pg 3980, 2006)'. J Clin Microbiol, 45 (55):1671-16711671   [Details]
(2006)'Culture-independent analyses of temporal variation of the dominant fecal microbiota and targeted bacterial subgroups in Crohn's disease'
Scanlan, P. D.,Shanahan, F.,O'Mahony, C.,Marchesi, J. R. (2006) 'Culture-independent analyses of temporal variation of the dominant fecal microbiota and targeted bacterial subgroups in Crohn's disease'. Journal of Clinical Microbiology, 44 (11):3980-3988   [Details]
(2005)'Serial culture-independent analysis of the enteric microbial community in Crohn's disease and disease controls'
Marchesi, J.,Scanlan, P.,Codling, C.,MacSharry, J.,Kiely, B.,O'Mahony, L.,Collins, J. K.,Quigley, E.,Shanahan, F. (2005) 'Serial culture-independent analysis of the enteric microbial community in Crohn's disease and disease controls'. Gastroenterology, 128 (44)   [Details]

Professional Activities

Professional Associations

 AssociationFunctionFrom / To
Society for Applied Microbiology Member/
European Society for Evolutionary Biology Member/
Microbiology Society Member/

Employment

 EmployerPositionFrom / To
APC Microbiome Institute, University College Cork Royal Society – Science Foundation Ireland University Research Fellow/

Education

 YearInstitutionQualificationSubject
2002UCC BScPlant and Microbiology Biotechnology
2007UCC PhDMedicine
2014UCC PG CertificateTeaching and Learning in Higher Education
2016UCC PG CertificateProfessional Skills for Research Leaders

Research Information

External Collaborators

 NameOrganisation / InstituteCountry
Dr Alex Hall ETH ZurichSWITZERLAND
Prof. Angus Buckling University of ExeterUNITED KINGDOM
Dr Rune Stensvold Staten Serum InsitutDENMARK
Prof. Maria Gloria Dominguez-Bello New York UniversityU.S.A.
Dr Paul Cotter Teagasc, MooreparkIRELAND

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School of Microbiology

Microbiology Office, Room FSB452 4th Floor Food Science & Technology Building University College Cork, Cork

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