Research Profile

Biography

Karen is a staff research scientist at TNI since 2007. She has a PhD in microelectronics and a degree in electrical engineering. She joined TNI as a postdoctoral researcher in 2002 to develop an electronic tongue sensor system to monitor milk freshness. She has successfully participated in both national and international projects on biosensor development for bioterrorism agent monitoring, nanopore technology for DNA analysis and minimally invasive systems for early disease detection. Her research interests include micro- and nano-sensor design and development, electrochemical sensor characterization, simulation and development of data analysis methods for complex solutions for environmental, medical, and security applications.

Research Interests

electrochemical sensors, nanopores, biosensors.

Research Grants

 ProjectFunding
Body
Start DateEnd DateAward
Artificial gut trials with sensor systemEnterprise Ireland
Label-free detection of Listeria monocytogenes using electrochemical sensor incorporating specific surface biofunctionalization methodsScience Foundation Ireland
Non-invasive approach to diagnose intestinal diseasesEnterprise Irl01-JAN-0931-DEC-10€99,725.00
EI "Development of a Diagnostic Swallowable Capsule to Investigate the GI Tract Environment .."Enterprise Irl01-OCT-0531-JUL-09€341,563.00
DAFF "14/F/883" - Development of SPORE ANALYSIS CRITICAL CONTROL POINT (SACCP) charts for application in dairy manufacturing processDepartment of Agriculture Fisheries & Forestry (DAFF)01-DEC-1430-NOV-18€271,849.00
EI FP/2010/602 Travel SupportEnterprise Irl14-FEB-1028-FEB-15€1,200.00
Design of an on-chip potentiostatScience Foundation Ireland
Development of SPORE ANALYSIS CRITICAL CONTROL POINT (SACCP) chartsDepartment of Agriculture, Fisheries & Food (DAFF)01-DEC-14
EI - Travel SupportEnterprise Irl23-JUN-0903-NOV-09€800.00
Label-free detection of colorectal cancer biomarkers using a nanostructured device which applies electrochemical methods to investigate the biomarker ion transfer behaviourScience Foundation Ireland

Publications

Book Chapters

 YearPublication
(2014)'Development of an Electrochemical Sensing System for Environmental Monitoring of Port Water Quality to Integrate On-board an Autonomous Robotic Fish'
V.I. Ogurtsov, K.Twomey,G.Herzog (2014) 'Development of an Electrochemical Sensing System for Environmental Monitoring of Port Water Quality to Integrate On-board an Autonomous Robotic Fish' In: Comprehensive Materials Processing Technology. n/a: Elsevier Science. [Details]

Peer Reviewed Journals

 YearPublication
(2009)'Swallowable capsule technology: current perspectives and future directions'
Twomey K, Marchesi JR (2009) 'Swallowable capsule technology: current perspectives and future directions'. Endoscopy, 41 (4):357-362 [DOI] [Details]
(2013)'On-chip electrochemical microsystems for measurements of copper and conductivity in artificial seawater'
Herzog, G,Moujahid, W,Twomey, K,Lyons, C,Ogurtsov, VI (2013) 'On-chip electrochemical microsystems for measurements of copper and conductivity in artificial seawater'. Talanta, 116 :26-32 [DOI] [Details]
(2008)'Swallowable-capsule technology'
C. Mc Caffrey; O.Chevalerias; C.O'Mathuna; K.Twomey (2008) 'Swallowable-capsule technology'. IEEE Pervasive Computing, [Details]
(2006)'A portable sensing system for electronic tongue operations'
Twomey, K,Truemper, A,Murphy, K; (2006) 'A portable sensing system for electronic tongue operations'. Sensors, 6 :1679-1696 [Details]
(2009)'Fabrication and characterization of a miniaturized planar voltammetric sensor array for use in an electronic tongue'
Twomey, K,de Eulate, EA,Alderman, J,Arrigan, DWM; (2009) 'Fabrication and characterization of a miniaturized planar voltammetric sensor array for use in an electronic tongue'. Sensors and Actuators B-Chemical, 140 :532-541 [DOI] [Details]
(2011)'Characterization of the Electrochemical Behavior of Gastrointestinal Fluids Using a Multielectrode Sensor Probe'
Twomey, K,de Eulate, EA,Marchesi, JR,Kolida, S,Gibson, G,Arrigan, DWM,Ogurtsov, VI; (2011) 'Characterization of the Electrochemical Behavior of Gastrointestinal Fluids Using a Multielectrode Sensor Probe'. IEEE Transactions On Biomedical Engineering, 58 :2521-2527 [DOI] [Details]

Teaching Activities

Teaching Interests

                         

coordinates the BioMEMS lectures in the Microsystems course (UE6008). lectures in Microsystems CM6014 as part of the MSc in Analytical Chemistry.

Microsystems, analytical chemistry, Nanotechnology, electrochemical sensors

Recent Postgraduates

 Graduation YearStudent NameInstitutionDegree TypeThesis Title
2010Eva Alvarez NUI (UCC)MScInvestigation of an electronic tongue array for gastro-intestinal disease detection’
2012Aoife Ryan NUI (UCC)MScDevelopment of an Electroanalytical Methodology for the Detection of Contaminants (Phenol) in Seawater
2013Shane McGilllycuddy NUI (UCC)MScA hybrid solid-state nanopore array for label-free DNA and Toxin detection.
2015Suzanne O'Callaghan UCDMEngScUse of dental implants for monitoring oral health and inflammation
2014Sarah Harney NUI (UCC)MScLABEL-FREE DETECTION OF COLORECTAL CANCER BIOMARKERS USING A NANOSTRUCTURED DEVICE WHICH APPLIES ELECTROCHEMICAL METHODS TO INVESTIGATE THE BIOMARKER ION TRANSFER BEHAVIOUR
2008Colm McCaffrey NUI (UCC)MEngScDEVELOPMENT OF CIRCUITRY AND
2010Rakesh Kumar NUI (UCC)MScElectrochemical Characterization of a disposable three

Research Information

Internal Collaborators

 NameInstituteCountry
Jadavpur University INDIA

External Collaborators

 NameOrganisation/ InstitutionCountry
School of Dentistry UCCIRELAND
Moorepark, Teagasc IRELAND
Queens University UNITED KINGDOM
Haute Ecole Arc Ingénierie SWITZERLAND
Imperial College London UNITED KINGDOM
Trinity Academic Gastroenterology Group IRELAND
Tallaght Hospital

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University College Cork

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