Research Profile

John F Cryan

Biography

John F. Cryan is Professor & Chair, Dept. of Anatomy & Neuroscience, University College Cork and was appointed Vice President for Research & Innovation in March 2021.  He is also a Principal Investigator in the APC Microbiome Institute. He received a B.Sc. (Hons) in Biochemistry and PhD in Pharmacology from the National University of Ireland, Galway, Ireland and was a visiting fellow at the Dept Psychiatry, University of Melbourne, Australia, which was followed by postdoctoral fellowships at the University of Pennsylvania, Philadelphia, USA and The Scripps Research Institute, La Jolla, California. He spent four years as a Group Leader in the pharmaceutical industry at the Novartis Institutes for BioMedical Research in Basel Switzerland prior to joining UCC in 2005. Prof. Cryan's current research is focused on understanding the interaction between brain, gut & microbiome and how it applies to stress, psychiatric and immune-related disorders at key time-windows across the lifespan. Prof. Cryan has published over 600 peer-reviewed articles and book chapters and has a H-index of 132 (Google Scholar; July 2021). He is a Senior Editor of Neuropharmacology and of Neurobiology of Stress. He is on the editorial board of a further 15 journals. He has co-edited four books and is co-author of the bestselling  “The Psychobiotic Revolution: Mood, Food, and the New Science of the Gut-Brain Connection” (National Geographic Press, 2017). He has received numerous awards including UCC Researcher of the Year in 2012,  the University of Utrecht Award for Excellence in Pharmaceutical Research in 2013, UCC Research Communicator of the Year 2017, and being named on the Thomson Reuters Highly Cited Researcher list in 2014 and Clarivate Analytics Highly Cited Researcher list each year from 2017. He was elected a Member of the Royal Irish Academy in 2017 and has served on UCC’s Governing Body for 6 years. He also received a Research Mentor Award from the American Gastroenterology Association and the Tom Connor Distinguished Scientist Award from Neuroscience Ireland in 2017 and was awarded an honorary degree from the University of Antwerp, Belgium in 2018. He was a TEDMED speaker in Washington in 2014 and is Past-President of the European Behavioural Pharmacology Society.

Research Interests

Prof. Cryan's current research interests include the neurobiological basis of stress-related neuropsychiatric disorders including depression, anxiety and drug dependence. Moreover, his group is also focused on understanding the interaction between brain, gut & microbiome and how it applies to stress and immune-related disorders, including irritable bowel syndrome and obesity and neurodevelopmental disorders such as autism. He is also interested in applying novel approaches to facilitate drug/siRNA delivery to the brain in vivo.

Prof. Cryan's research group consists of 12 Postdoctoral Fellows, 14 PhD students, 2 MD students, 2 MSc Students, 3 research scientists and various visiting students from Ireland, Spain, The Netherlands, USA & Canada. It is funded by Science Foundation Ireland, the Health Research Board, Enterprise Ireland and the Irish Research Council. Moreover, Prof. Cryan receives funding as a PI on the two different EU Framework 7 Programme grants.

Publications

Books

 YearPublication
(2016)Gut Microbiome and Behavior, Volume 131.
John F. Cryan Gerard Clarke (2016) Gut Microbiome and Behavior, Volume 131. Amsterdam: Academic Press. [Details]
(2017)The Psychobiotic Revolution.
Scott C. Anderson, John F. Cryan & Ted Dinan (2017) The Psychobiotic Revolution. Washington, DC: National Geographic Press. [Details]
(2014)Microbial Endocrinology: The Microbiota-Gut-Brain Axis in Health and Disease.
Mark Lyte John F. Cryan (2014) Microbial Endocrinology: The Microbiota-Gut-Brain Axis in Health and Disease. Heidelberg: Springer. [Details]
(2010)Depression: From psychopathology to pharmacotherapy.
Cryan J.;Leonard B. (2010) Depression: From psychopathology to pharmacotherapy. [DOI] [Details]
(2012)Behavioural Neurogenetics.
John F. Cryan Andreas Reif (2012) Behavioural Neurogenetics. Heidelberg: Springer. [Details]
(2010)Depression: From Psychopathology to Pharmacotherapy.
Cryan, JF and Leonard, BE; (2010) Depression: From Psychopathology to Pharmacotherapy. Basel: Karger. [Details]

Peer Reviewed Journals

 YearPublication
(2021)'The effect of exercise interventions on inflammatory markers in major depressive disorder: protocol for a systematic review and meta-analysis'
Grunberg D, Martin JA, Cryan JF, O’Halloran KD, Kelleher E, Dinan TG and Clarke G (2021) 'The effect of exercise interventions on inflammatory markers in major depressive disorder: protocol for a systematic review and meta-analysis'. Hrb Open Research, [Details]
(2020)'A biological framework for emotional dysregulation in alcohol misuse: from gut to brain'
Carbia, C;Lannoy, S;Maurage, P;Lopez-Caneda, E;O'Riordan, KJ;Dinan, TG;Cryan, JF (2020) 'A biological framework for emotional dysregulation in alcohol misuse: from gut to brain'. Molecular Psychiatry, [DOI] [Details]
(2020)'Enduring neurobehavioral effects induced by microbiota depletion during the adolescent period'
Lach, G;Fulling, C;Bastiaanssen, TFS;Fouhy, F;O' Donovan, AN;Ventura-Silva, AP;Stanton, C;Dinan, TG;Cryan, JF (2020) 'Enduring neurobehavioral effects induced by microbiota depletion during the adolescent period'. Translational Psychiatry, 10 [DOI] [Details]
(2020)'A specific dietary fibre supplementation improves cognitive performance-an exploratory randomised, placebo-controlled, crossover study'
Berding, K;Long-Smith, CM;Carbia, C;Bastiaanssen, TFS;van de Wouw, M;Wiley, N;Strain, CR;Fouhy, F;Stanton, C;Cryan, JF;Dinan, TG (2020) 'A specific dietary fibre supplementation improves cognitive performance-an exploratory randomised, placebo-controlled, crossover study'. Journal of Psychopharmacology, [DOI] [Details]
(2020)'Enduring Behavioral Effects Induced by Birth by Caesarean Section in the Mouse'
Morais L.H.;Golubeva A.V.;Moloney G.M.;Moya-Pérez A.;Ventura-Silva A.P.;Arboleya S.;Bastiaanssen T.F.S.;O'Sullivan O.;Rea K.;Borre Y.;Scott K.A.;Patterson E.;Cherry P.;Stilling R.;Hoban A.E.;El Aidy S.;Sequeira A.M.;Beers S.;Moloney R.D.;Renes I.B.;Wang S.;Knol J.;Ross R.P.;O'Toole P.W.;Cotter P.D.;Stanton C.;Dinan T.G.;Cryan J.F. (2020) 'Enduring Behavioral Effects Induced by Birth by Caesarean Section in the Mouse'. Current Biology, [DOI] [Details]
(2020)'Prebiotic administration modulates gut microbiota and faecal short-chain fatty acid concentrations but does not prevent chronic intermittent hypoxia-induced apnoea and hypertension in adult rats: Role of the microbiota-gut-brain axis in CIH-induced cardiorespiratory dysfunction'
O'Connor K.M.;Lucking E.F.;Bastiaanssen T.F.S.;Peterson V.L.;Crispie F.;Cotter P.D.;Clarke G.;Cryan J.F.;O'Halloran K.D. (2020) 'Prebiotic administration modulates gut microbiota and faecal short-chain fatty acid concentrations but does not prevent chronic intermittent hypoxia-induced apnoea and hypertension in adult rats: Role of the microbiota-gut-brain axis in CIH-induced cardiorespiratory dysfunction'. Ebiomedicine, 59 [DOI] [Details]
(2020)'Investigating the potential of fish oil as a nutraceutical in an animal model of early life stress'
Egerton, S;Donoso, F;Fitzgerald, P;Gite, S;Fouhy, F;Whooley, J;Dinan, TG;Cryan, JF;Culloty, SC;Ross, RP;Stanton, C (2020) 'Investigating the potential of fish oil as a nutraceutical in an animal model of early life stress'. Nutritional Neuroscience, [DOI] [Details]
(2020)'Enduring effects of an unhealthy diet during adolescence on systemic but not neurobehavioural measures in adult rats'
Nicolas, S;Leime, CSO;Hoban, AE;Hueston, CM;Cryan, JF;Nolan, YM (2020) 'Enduring effects of an unhealthy diet during adolescence on systemic but not neurobehavioural measures in adult rats'. Nutritional Neuroscience, [DOI] [Details]
(2020)'Age- and duration-dependent effects of whey protein on high-fat diet-induced changes in body weight, lipid metabolism, and gut microbiota in mice'
Boscaini S.;Cabrera-Rubio R.;Nychyk O.;Roger Speakman J.;Francis Cryan J.;David Cotter P.;Nilaweera K.N. (2020) 'Age- and duration-dependent effects of whey protein on high-fat diet-induced changes in body weight, lipid metabolism, and gut microbiota in mice'. Physiological reports, 8 (15) [DOI] [Details]
(2020)'Investigating the potential of fish oil as a nutraceutical in an animal model of early life stress'
Egerton S.;Donoso F.;Fitzgerald P.;Gite S.;Fouhy F.;Whooley J.;Dinan T.G.;Cryan J.F.;Culloty S.C.;Ross R.P.;Stanton C. (2020) 'Investigating the potential of fish oil as a nutraceutical in an animal model of early life stress'. Nutritional Neuroscience, [DOI] [Details]
(2020)'Adult-born neurons from the dorsal, intermediate, and ventral regions of the longitudinal axis of the hippocampus exhibit differential sensitivity to glucocorticoids'
Levone, BR;Codagnone, MG;Moloney, GM;Nolan, YM;Cryan, JF;O' Leary, OF (2020) 'Adult-born neurons from the dorsal, intermediate, and ventral regions of the longitudinal axis of the hippocampus exhibit differential sensitivity to glucocorticoids'. Molecular Psychiatry, [DOI] [Details]
(2020)'Prebiotic administration modulates gut microbiota and faecal short-chain fatty acid concentrations but does not prevent chronic intermittent hypoxia-induced apnoea and hypertension in adult rats'
O’Connor KM, Lucking EF, Bastiaanssen TFS, Peterson VL, Crispie F, Cotter PD, Clarke G, Cryan JF, O’Halloran KD (2020) 'Prebiotic administration modulates gut microbiota and faecal short-chain fatty acid concentrations but does not prevent chronic intermittent hypoxia-induced apnoea and hypertension in adult rats'. Ebiomedicine, [Details]
(2020)'Bugs, breathing and blood pressure: Microbiota-gut-brain axis signalling in cardiorespiratory control in health and disease'
O'Connor KM, Lucking EF, Cryan JF & O'Halloran KD (2020) 'Bugs, breathing and blood pressure: Microbiota-gut-brain axis signalling in cardiorespiratory control in health and disease'. The Journal of Physiology, [Details]
(2020)'Ethologically based behavioural and neurochemical characterisation of mice with isoform-specific loss of dysbindin-1A in the context of schizophrenia'
O'Tuathaigh C.M.P.;Desbonnet L.;Payne C.;Petit E.;Cox R.;Loftus S.;Clarke G.;Cryan J.F.;Tighe O.;Wilson S.;Kirby B.P.;Dinan T.G.;Waddington J.L. (2020) 'Ethologically based behavioural and neurochemical characterisation of mice with isoform-specific loss of dysbindin-1A in the context of schizophrenia'. Neuroscience Letters, 736 [DOI] [Details]
(2020)'Adult-born neurons from the dorsal, intermediate, and ventral regions of the longitudinal axis of the hippocampus exhibit differential sensitivity to glucocorticoids'
Levone B.R.;Codagnone M.G.;Moloney G.M.;Nolan Y.M.;Cryan J.F.;O’ Leary O.F. (2020) 'Adult-born neurons from the dorsal, intermediate, and ventral regions of the longitudinal axis of the hippocampus exhibit differential sensitivity to glucocorticoids'. Molecular Psychiatry, [DOI] [Details]
(2020)'Mapping O-2 concentration in ex-vivo tissue samples on a fast PLIM macro-imager'
Sen, R;Zhdanov, AV;Bastiaanssen, TFS;Hirvonen, LM;Svihra, P;Fitzgerald, P;Cryan, JF;Andersson-Engels, S;Nomerotski, A;Papkovsky, DB (2020) 'Mapping O-2 concentration in ex-vivo tissue samples on a fast PLIM macro-imager'. Scientific Reports, 10 [DOI] [Details]
(2020)'Dietary vitamin A supplementation prevents early obesogenic diet-induced microbiota, neuronal and cognitive alterations'
Biyong, EF;Alfos, S;Dumetz, F;Helbling, JC;Aubert, A;Brossaud, J;Foury, A;Moisan, MP;Lay, S;Richard, E;Patterson, E;Murphy, K;Rea, K;Stanton, C;Schellekens, H;Cryan, JF;Capuron, L;Pallet, V;Ferreira, G (2020) 'Dietary vitamin A supplementation prevents early obesogenic diet-induced microbiota, neuronal and cognitive alterations'. International Journal of Obesity, [DOI] [Details]
(2021)'Molecular, biochemical and behavioural evidence for a novel oxytocin receptor and serotonin 2C receptor heterocomplex'
Chruscicka, B;Cowan, CSM;Fitzsimons, SEW;Borroto-Escuela, DO;Druelle, CM;Stamou, P;Bergmann, CA;Dinan, TG;Slattery, DA;Fuxe, K;Cryan, JF;Schellekens, H (2021) 'Molecular, biochemical and behavioural evidence for a novel oxytocin receptor and serotonin 2C receptor heterocomplex'. Neuropharmacology, 183 [DOI] [Details]
(2021)'eNEUROANAT-CF: a Conceptual Instructional Design Framework for Neuroanatomy e-Learning Tools'
Javaid M.A., Schellekens H., Cryan J.F., Toulouse A. (2021) 'eNEUROANAT-CF: a Conceptual Instructional Design Framework for Neuroanatomy e-Learning Tools'. Medical Science Educator, [DOI] [Details]
(2020)'Neuroanatomy of the spinal pathways: Evaluation of an interactive multimedia e-learning resource'
Javaid M., Schellekens H., Cryan J.F., Toulouse A. (2020) 'Neuroanatomy of the spinal pathways: Evaluation of an interactive multimedia e-learning resource'. MedEdPublish, :1-23 [DOI] [Details]
(2020)'Identifying a biological signature of prenatal maternal stress'
Keane JM;Khashan AS;McCarthy FP;Kenny LC;Collins JM;O'Donovan SM;Brown JR;Cryan JF;Dinan TG;Clarke G;O'Mahony SM; (2020) 'Identifying a biological signature of prenatal maternal stress'. Jci Insight, [DOI] [Details]
(2020)'Gut microbiota modulates expression of genes involved in the astrocyte-neuron lactate shuttle in the hippocampus'
Margineanu, MB;Sherwin, E;Golubeva, A;Peterson, V;Hoban, A;Fiumelli, H;Rea, K;Cryan, JF;Magistretti, PJ (2020) 'Gut microbiota modulates expression of genes involved in the astrocyte-neuron lactate shuttle in the hippocampus'. European Neuropsychopharmacology, 41 :152-159 [DOI] [Details]
(2020)'You’ve got male: Sex and the microbiota-gut-brain axis across the lifespan'
Jaggar, Minal; Rea, Kieran; Spichak, Simon; Dinan, Timothy G.; Cryan, John F. (2020) 'You’ve got male: Sex and the microbiota-gut-brain axis across the lifespan'. Frontiers In Neuroendocrinology, 56 :100815-1-100815-1-22   [DOI] [Full Text] [Details]
(2020)'The role of the microbiota in acute stress-induced myeloid immune cell trafficking'
van de Wouw, Marcel,Lyte, Joshua M.,Boehme, Marcus,Sichetti, Marzia,Moloney, Gerard,Goodson, Michael S.,Kelley-Loughnane, Nancy,Dinan, Timothy G.,Clarke, Gerard,Cryan, John F. (2020) 'The role of the microbiota in acute stress-induced myeloid immune cell trafficking'. Brain, Behavior, and Immunity,   [DOI] [Full Text] [Details]
(2020)'Annual Research Review: Critical windows – the microbiota–gut–brain axis in neurocognitive development'
Cowan, Caitlin S. M.; Dinan, Timothy G.; Cryan, John F. (2020) 'Annual Research Review: Critical windows – the microbiota–gut–brain axis in neurocognitive development'. Journal Of Child Psychology And Psychiatry,   [DOI] [Full Text] [Details]
(2020)'Adolescent dietary manipulations differentially affect gut microbiota composition and amygdala neuroimmune gene expression in male mice in adulthood'
Fülling C.;Lach G.;Bastiaanssen T.F.S.;Fouhy F.;O'Donovan A.N.;Ventura-Silva A.P.;Stanton C.;Dinan T.G.;Cryan J.F. (2020) 'Adolescent dietary manipulations differentially affect gut microbiota composition and amygdala neuroimmune gene expression in male mice in adulthood'. Brain Behav Immun, [DOI] [Details]
(2020)'Informal caregiving for dementia patients: the contribution of patient characteristics and behaviours to caregiver burden'
Allen, AP;Buckley, MM;Cryan, JF;Chorcorain, AN;Dinan, TG;Kearney, PM;O'Caoimh, R;Calnan, M;Clarke, G;Molloy, DW (2020) 'Informal caregiving for dementia patients: the contribution of patient characteristics and behaviours to caregiver burden'. Age and Ageing, 49 :52-56 [DOI] [Details]
(2020)'Towards a psychobiotic therapy for depression: Bifidobacterium breve CCFM1025 reverses chronic stress-induced depressive symptoms and gut microbial abnormalities in mice'
Tian P.;O'Riordan K.J.;Lee Y.k.;Wang G.;Zhao J.;Zhang H.;Cryan J.F.;Chen W. (2020) 'Towards a psychobiotic therapy for depression: Bifidobacterium breve CCFM1025 reverses chronic stress-induced depressive symptoms and gut microbial abnormalities in mice'. Neurobiology of Stress, 12 [DOI] [Details]
(2020)'The role of the gut microbiome in the development of schizophrenia'
Kelly J.R.;Minuto C.;Cryan J.F.;Clarke G.;Dinan T.G. (2020) 'The role of the gut microbiome in the development of schizophrenia'. Schizophrenia Research, [DOI] [Details]
(2020)'Developing a quantitative method to assess the decomposition of embalmed human cadavers'
Balta J.Y.;Blom G.;Davidson A.;Perrault K.;Cryan J.F.;O'Mahony S.M.;Cassella J.P. (2020) 'Developing a quantitative method to assess the decomposition of embalmed human cadavers'. Forensic Chemistry, 18 [DOI] [Details]
(2020)'Gut-brain axis serotonergic responses to acute stress exposure are microbiome-dependent'
Lyte J.M.;Gheorghe C.E.;Goodson M.S.;Kelley-Loughnane N.;Dinan T.G.;Cryan J.F.;Clarke G. (2020) 'Gut-brain axis serotonergic responses to acute stress exposure are microbiome-dependent'. Neurogastroenterology and Motility, [DOI] [Details]
(2020)'Behavioural characterization of ghrelin ligands, anamorelin and HM01: Appetite and reward-motivated effects in rodents'
Howick K.;Chruscicka B.;Felice D.;Ramirez V.;van Leuven L.;Pietra C.;Cryan J.;Griffin B.;Schellekens H. (2020) 'Behavioural characterization of ghrelin ligands, anamorelin and HM01: Appetite and reward-motivated effects in rodents'. Neuropharmacology, 168 [DOI] [Details]
(2020)'Depression's Unholy Trinity: Dysregulated Stress, Immunity, and the Microbiome'
Cruz-Pereira JS;Rea K;Nolan YM;O'Leary OF;Dinan TG;Cryan JF; (2020) 'Depression's Unholy Trinity: Dysregulated Stress, Immunity, and the Microbiome'. Annual Review Of Psychology, 71 [DOI] [Details]
(2020)'Revisiting the behavioral genetics of serotonin: relevance to anxiety and depression'
O'Leary O.;Codagnone M.;Cryan J. (2020) 'Revisiting the behavioral genetics of serotonin: relevance to anxiety and depression'. Handbook Of Anxiety And Fear, 31 :665-709 [DOI] [Details]
(2020)'Resveratrol and metabolic health in COPD: A proof-of-concept randomized controlled trial'
Beijers R.;Gosker H.;Sanders K.;de Theije C.;Kelders M.;Clarke G.;Cryan J.;van den Borst B.;Schols A. (2020) 'Resveratrol and metabolic health in COPD: A proof-of-concept randomized controlled trial'. Clinical Nutrition (Edinburgh, Scotland), [DOI] [Details]
(2020)'Gut-brain axis serotonergic responses to acute stress exposure are microbiome-dependent'
Lyte, JM;Gheorghe, CE;Goodson, MS;Kelley-Loughnane, N;Dinan, TG;Cryan, JF;Clarke, G (2020) 'Gut-brain axis serotonergic responses to acute stress exposure are microbiome-dependent'. Neurogastroenterology and Motility, [DOI] [Details]
(2020)'Structural and functional MRI of altered brain development in a novel adolescent rat model of quinpirole-induced compulsive checking behavior'
Straathof M.;Blezer E.L.A.;van Heijningen C.;Smeele C.E.;van der Toorn A.;Otte W.M.;Dijkhuizen R.M.;Buitelaar J.K.;Glennon J.C.;Buitelaar J.K.;Otte W.M.;Buitelaar J.;de Ruiter S.;Naaijen J.;Akkermans S.;Mennes M.;Zwiers M.;Ilbegi S.;Hennissen L.;Glennon J.;van de Vondervoort I.;Kapusta K.;Bielczyk N.A.;Amiri H.;Havenith M.;Franke B.;Poelmans G.;Bralten J.;Heskes T.;Sokolova E.;Groot P.;Williams S.;Murphy D.A.;Lythgoe D.;Bruchhage M.;Dud I.;Voinescu B.;Dittmann R.;Banaschewski T.;Brandeis D.;Mechler K.;Berg R.;Wolf I.;Häge A.;Landauer M.;Hohmann S.;Schlier R.B.;Ruff M.;Mandl R.;Dijkhuizen R.;Blezer E.;Straathof M.;van der Marel K.;Pullens P.;Mol W.;van der Toorn A.;Otte W.;van Heijningen C.;Durston S.;Mensen V.A.;Oranje B.;Joel D.;Cryan J.;Petryshen T.;Pauls D.;Saito M.;Heckman A.;Bahn S.;Schwalber A.;Florea I. (2020) 'Structural and functional MRI of altered brain development in a novel adolescent rat model of quinpirole-induced compulsive checking behavior'. European Neuropsychopharmacology, [DOI] [Details]
(2020)'Sex-dependent associations between addiction-related behaviors and the microbiome in outbred rats'
Peterson V.L.;Richards J.B.;Meyer P.J.;Cabrera-Rubio R.;Tripi J.A.;King C.P.;Polesskaya O.;Baud A.;Chitre A.S.;Bastiaanssen T.F.S.;Woods L.S.;Crispie F.;Dinan T.G.;Cotter P.D.;Palmer A.A.;Cryan J.F. (2020) 'Sex-dependent associations between addiction-related behaviors and the microbiome in outbred rats'. Ebiomedicine, 55 [DOI] [Details]
(2020)'Distinct actions of the fermented beverage kefir on host behaviour, immunity and microbiome gut-brain modules in the mouse'
van de Wouw M.;Walsh A.M.;Crispie F.;van Leuven L.;Lyte J.M.;Boehme M.;Clarke G.;Dinan T.G.;Cotter P.D.;Cryan J.F. (2020) 'Distinct actions of the fermented beverage kefir on host behaviour, immunity and microbiome gut-brain modules in the mouse'. Microbiome, 8 (1) [DOI] [Details]
(2020)'Recipe for a Healthy Gut: Intake of Unpasteurised Milk Is Associated with Increased Lactobacillus Abundance in the Human Gut Microbiome'
Butler M.I.;Bastiaanssen T.F.S.;Long-Smith C.;Berding K.;Morkl S.;Cusack A.M.;Strain C.;Busca K.;Porteous-Allen P.;Claesson M.J.;Stanton C.;Cryan J.F.;Allen D.;Dinan T.G. (2020) 'Recipe for a Healthy Gut: Intake of Unpasteurised Milk Is Associated with Increased Lactobacillus Abundance in the Human Gut Microbiome'. Nutrients, 12 (5) [DOI] [Details]
(2020)'Gut microbiome-mediated modulation of hepatic cytochrome P450 and P-glycoprotein: impact of butyrate and fructo-oligosaccharide-inulin'
Walsh, J;Gheorghe, CE;Lyte, JM;van de Wouw, M;Boehme, M;Dinan, TG;Cryan, JF;Griffin, BT;Clarke, G;Hyland, NP (2020) 'Gut microbiome-mediated modulation of hepatic cytochrome P450 and P-glycoprotein: impact of butyrate and fructo-oligosaccharide-inulin'. Journal of Pharmacy and Pharmacology, [DOI] [Details]
(2020)'Stress resilience during the coronavirus pandemic'
Vinkers C.H.;van Amelsvoort T.;Bisson J.I.;Branchi I.;Cryan J.F.;Domschke K.;Howes O.D.;Manchia M.;Pinto L.;de Quervain D.;Schmidt M.V.;van der Wee N.J.A. (2020) 'Stress resilience during the coronavirus pandemic'. European Neuropsychopharmacology, [DOI] [Details]
(2020)'Natural compulsive-like behaviour in the deer mouse (Peromyscus maniculatus bairdii) is associated with altered gut microbiota composition'
Scheepers, Isabella M.; Cryan, John F.; Bastiaanssen, Thomaz F. S.; Rea, Kieran; Clarke, Gerard; Jaspan, Heather B.; Harvey, Brian H.; Hemmings, Sian M. J.; Santana, Leonard; van der Sluis, Rencia; Malan-Müller, Stefanie; Wolmarans, De Wet (2020) 'Natural compulsive-like behaviour in the deer mouse (Peromyscus maniculatus bairdii) is associated with altered gut microbiota composition'. European Journal of Neuroscience,   [DOI] [Full Text] [Details]
(2020)'When rhythms meet the blues: Circadian interactions with the microbiota-gut-brain axis'
Teichman, Emily M.; O’Riordan, Kenneth J.; Gahan, Cormac G. M.; Dinan, Timothy G.; Cryan, John F. (2020) 'When rhythms meet the blues: Circadian interactions with the microbiota-gut-brain axis'. Cell Metabolism, 31 (3):448-471 [DOI] [Full Text] [Details]
(2020)'Evaluation of Neuroanatomy Web Resources for Undergraduate Education: Educators’ and Students’ Perspectives'
Javaid M., Schellekens H., Cryan J.F., Toulouse A. (2020) 'Evaluation of Neuroanatomy Web Resources for Undergraduate Education: Educators’ and Students’ Perspectives'. Anatomical Sciences Education, 13 (2):237-249 [DOI] [Details]
(2020)'Strain differences in behaviour and immunity in aged mice: Relevance to autism'
O’Connor, Rory; Van De Wouw, Marcel; Moloney, Gerard M.; Ventura-Silva, Ana Paula; O’Riordan, Ken; Golubeva, Anna; Dinan, Timothy G.; Schellekens, Harriët; Cryan, John F. (2020) 'Strain differences in behaviour and immunity in aged mice: Relevance to autism'. Behavioural Brain Research, [DOI] [Full Text] [Details]
(2020)'Polyphenols selectively reverse early-life stress-induced behavioural, neurochemical and microbiota changes in the rat'
Donoso, Francisco; Egerton, Sian; Bastiaanssen, Thomaz F. S.; Fitzgerald, Patrick; Gite, Snehal; Fouhy, Fiona; Ross, R. Paul; Stanton, Catherine; Dinan, Timothy G.; Cryan, John F. (2020) 'Polyphenols selectively reverse early-life stress-induced behavioural, neurochemical and microbiota changes in the rat'. Psychoneuroendocrinology, [DOI] [Full Text] [Details]
(2019)'Microbiota and Neurodevelopmental Trajectories: Role of Maternal and Early-Life Nutrition'
Codagnone M.;Stanton C.;O'Mahony S.;Dinan T.;Cryan J. (2019) 'Microbiota and Neurodevelopmental Trajectories: Role of Maternal and Early-Life Nutrition'. Annals of Nutrition and Metabolism, 74 (Suppl2):16-27 [DOI] [Details]
(2019)'Enduring effects of muscarinic receptor activation on adult hippocampal neurogenesis, microRNA expression and behaviour'
Costa, APR;Levone, BR;Gururajan, A;Moloney, G;Hoeller, AA;Lino-de-Oliveira, C;Dinan, TG;O'Leary, OF;de Lima, TCM;Cryan, JF (2019) 'Enduring effects of muscarinic receptor activation on adult hippocampal neurogenesis, microRNA expression and behaviour'. Behavioural Brain Research, 362 :188-198 [DOI] [Details]
(2019)'Increased amygdalar metabotropic glutamate receptor 7 mRNA in a genetic mouse model of impaired fear extinction'
O'Connor RM1, McCafferty CP, Bravo JA, Singewald N, Holmes A, Cryan JF (2019) 'Increased amygdalar metabotropic glutamate receptor 7 mRNA in a genetic mouse model of impaired fear extinction'. Psychopharmacology, 236 (1) [DOI] [Details]
(2019)'Preventing adolescent stress-induced cognitive and microbiome changes by diet'
Provensi, G;Schmidt, SD;Boehme, M;Bastiaanssen, TFS;Rani, B;Costa, A;Busca, K;Fouhy, F;Strain, C;Stanton, C;Blandina, P;Izquierdo, I;Cryan, JF;Passani, MB (2019) 'Preventing adolescent stress-induced cognitive and microbiome changes by diet'. Proceedings of The National Academy of Sciences of The United States of America, 116 :9644-9651 [DOI] [Details]
(2019)'Microbiota and Neurodevelopmental Trajectories: Role of Maternal and Early-Life Nutrition'
Codagnone, MG;Stanton, C;O'Mahony, SM;Dinan, TG;Cryan, JF (2019) 'Microbiota and Neurodevelopmental Trajectories: Role of Maternal and Early-Life Nutrition'. Annals of Nutrition and Metabolism, 74 :16-27 [DOI] [Details]
(2019)'Gamma-aminobutyric acid-producing lactobacilli positively affect metabolism and depressive-like behaviour in a mouse model of metabolic syndrome'
Patterson, E;Ryan, PM;Wiley, N;Carafa, I;Sherwin, E;Moloney, G;Franciosi, E;Mandal, R;Wishart, DS;Tuohy, K;Ross, RP;Cryan, JF;Dinan, TG;Stanton, C (2019) 'Gamma-aminobutyric acid-producing lactobacilli positively affect metabolism and depressive-like behaviour in a mouse model of metabolic syndrome'. Scientific Reports, 9 [DOI] [Details]
(2019)'Differential effects of psychotropic drugs on microbiome composition and gastrointestinal function'
Cussotto S.;Strain C.;Fouhy F.;Strain R.;Peterson V.;Clarke G.;Stanton C.;Dinan T.;Cryan J. (2019) 'Differential effects of psychotropic drugs on microbiome composition and gastrointestinal function'. Journal of Psychopharmacology, 236 (5):1671-1685 [DOI] [Details]
(2019)'Programming Bugs: Microbiota and the Developmental Origins of Brain Health and Disease'
Codagnone, Martin G.; Spichak, Simon; O’Mahony, Siobhain M.; O’Leary, Olivia F.; Clarke, Gerard; Stanton, Catherine; Dinan, Timothy G.; Cryan, John F. (2019) 'Programming Bugs: Microbiota and the Developmental Origins of Brain Health and Disease'. Biological Psychiatry, 85 (2):150-163   [DOI] [Full Text] [Details]
(2019)'Gut-neuroimmune interactions: The unexpected role of the immune system in brain development'
Spichak S.;Dinan T.;Cryan J. (2019) 'Gut-neuroimmune interactions: The unexpected role of the immune system in brain development'. The Biochemist, 41 (1):36-41 [DOI] [Details]
(2019)'Natural compulsive-like behaviour in the deer mouse (Peromyscus maniculatus bairdii) is associated with altered gut microbiota composition'
Scheepers I.;Cryan J.;Bastiaanssen T.;Rea K.;Clarke G.;Jaspan H.;Harvey B.;Hemmings S.;Santana L.;van der Sluis R.;Malan-Müller S.;Wolmarans D. (2019) 'Natural compulsive-like behaviour in the deer mouse (Peromyscus maniculatus bairdii) is associated with altered gut microbiota composition'. The European Journal of Neuroscience, [DOI] [Details]
(2019)'TLX knockdown in the dorsal dentate gyrus of juvenile rats differentially affects adolescent and adult behaviour'
Kozareva, DA;Foley, T;Moloney, GM;Cryan, JF;Nolan, YM (2019) 'TLX knockdown in the dorsal dentate gyrus of juvenile rats differentially affects adolescent and adult behaviour'. Behavioural Brain Research, 360 :36-50 [DOI] [Details]
(2019)'The enduring effects of early-life stress on the microbiota-gut-brain axis are buffered by dietary supplementation with milk fat globule membrane and a prebiotic blend'
O'Mahony, SM;Neufeld, KAM;Waworuntu, RV;Pusceddu, MM;Manurung, S;Murphy, K;Strain, C;Laguna, MC;Peterson, VL;Stanton, C;Berg, BM;Dinan, TG;Cryan, JF (2019) 'The enduring effects of early-life stress on the microbiota-gut-brain axis are buffered by dietary supplementation with milk fat globule membrane and a prebiotic blend'. The European Journal of Neuroscience, [DOI] [Details]
(2019)'Chronic intrahippocampal interleukin-1β overexpression in adolescence impairs hippocampal neurogenesis but not neurogenesis-associated cognition'
Pawley LC, Hueston CM, O'Leary JD, Kozareva DA, Cryan JF, O'Leary OF, Nolan YM. (2019) 'Chronic intrahippocampal interleukin-1β overexpression in adolescence impairs hippocampal neurogenesis but not neurogenesis-associated cognition'. Brain Behav Immun, [DOI] [Details]
(2019)'Differential effects of adolescent and adult-initiated voluntary exercise on context and cued fear conditioning'
O'Leary JD;Hoban AE;Cryan JF;O'Leary OF;Nolan YM; (2019) 'Differential effects of adolescent and adult-initiated voluntary exercise on context and cued fear conditioning'. Neuropharmacology, 45 (Pt A):49-58 [DOI] [Details]
(2019)'A ghrelin receptor and oxytocin receptor heterocomplex impairs oxytocin mediated signalling'
Wallace Fitzsimons S.;Chruscicka B.;Druelle C.;Stamou P.;Nally K.;Dinan T.;Cryan J.;Schellekens H. (2019) 'A ghrelin receptor and oxytocin receptor heterocomplex impairs oxytocin mediated signalling'. Neuropharmacology, 152 :90-101 [DOI] [Details]
(2019)'Nutraceuticals to promote neuronal plasticity in response to corticosterone-induced stress in human neuroblastoma cells'
Gite S.;Ross R.;Kirke D.;Guihéneuf F.;Aussant J.;Stengel D.;Dinan T.;Cryan J.;Stanton C. (2019) 'Nutraceuticals to promote neuronal plasticity in response to corticosterone-induced stress in human neuroblastoma cells'. Nutritional Neuroscience, 22 (8):551-568 [DOI] [Details]
(2019)'Manipulation of gut microbiota blunts the ventilatory response to hypercapnia in adult rats'
O'Connor, KM;Lucking, EF;Golubeva, AV;Strain, CR;Fouhy, F;Cenit, MC;Dhaliwal, P;Bastiaanssen, TFS;Burns, DP;Stanton, C;Clarke, G;Cryan, JF;O'Halloran, KD (2019) 'Manipulation of gut microbiota blunts the ventilatory response to hypercapnia in adult rats'. Ebiomedicine, 44 :618-638 [DOI] [Details]
(2019)'Depression's Unholy Trinity: Dysregulated Stress, Immunity, and the Microbiome'
Pereira JDC, Rea K, Nolan YM, O'Leary OF, Dinan TG, Cryan JF. (2019) 'Depression's Unholy Trinity: Dysregulated Stress, Immunity, and the Microbiome'. Annual Review Of Psychology, [DOI] [Details]
(2019)'Talking about a microbiome revolution'
Cryan J.;Dinan T. (2019) 'Talking about a microbiome revolution'. Nature Microbiology, 4 (4):552-553 [DOI] [Details]
(2019)'Metabolome and microbiome profiling of a stress-sensitive rat model of gut-brain axis dysfunction'
Bassett S.;Young W.;Fraser K.;Dalziel J.;Webster J.;Ryan L.;Fitzgerald P.;Stanton C.;Dinan T.;Cryan J.;Clarke G.;Hyland N.;Roy N. (2019) 'Metabolome and microbiome profiling of a stress-sensitive rat model of gut-brain axis dysfunction'. Scientific Reports, 9 (1) [DOI] [Details]
(2019)'Microbiota manipulation disrupts brainstem neurochemistry and the ventilatory response to hypercapnia in adult rats'
*O’Connor KM, *Lucking EF, Golubeva AV, Strain CR, Fouhy F, Dhaliwala P, Bastiaanssen T, Burns DP, Stanton C, Clarke G, Cryan JF, O’Halloran KD (2019) 'Microbiota manipulation disrupts brainstem neurochemistry and the ventilatory response to hypercapnia in adult rats'. Ebiomedicine, [Details]
(2019)'Neurobehavioural effects of Lactobacillus rhamnosus GG alone and in combination with prebiotics polydextrose and galactooligosaccharide in male rats exposed to early-life stress'
Neufeld, KAM;O'Mahony, SM;Hoban, AE;Waworuntu, RV;Berg, BM;Dinan, TG;Cryan, JF (2019) 'Neurobehavioural effects of Lactobacillus rhamnosus GG alone and in combination with prebiotics polydextrose and galactooligosaccharide in male rats exposed to early-life stress'. Nutritional Neuroscience, 22 :425-434 [DOI] [Details]
(2019)'Enduring Effects of Muscarinic Receptor Activation on Adult 2 Hippocampal Neurogenesis, MicroRNA expression and Behaviour 3 4'
Ramos Costa AP, Levone BR; Gururajan A, Moloney G, Hoeller A, Lino-de-Oliveira C, Dinan TG, O’Leary OF, Monteiro de Lima TC, Cryan JF* (2019) 'Enduring Effects of Muscarinic Receptor Activation on Adult 2 Hippocampal Neurogenesis, MicroRNA expression and Behaviour 3 4'. Behavioural Brain Research, 362 :188-198 [Details]
(2019)'Metabolome and microbiome profiling of a stress-sensitive rat model of gut-brain axis dysfunction'
Bassett, SA;Young, W;Fraser, K;Dalziel, JE;Webster, J;Ryan, L;Fitzgerald, P;Stanton, C;Dinan, TG;Cryan, JF;Clarke, G;Hyland, N;Roy, NC (2019) 'Metabolome and microbiome profiling of a stress-sensitive rat model of gut-brain axis dysfunction'. Scientific Reports, 9 [DOI] [Details]
(2019)'Faecal microbiota transplants for depression – Who gives a crapsule?'
Green J.;Castle D.;Berk M.;Hair C.;Loughman A.;Cryan J.;Nierenberg A.;Athan E.;Jacka F. (2019) 'Faecal microbiota transplants for depression – Who gives a crapsule?'. The Australian and New Zealand Journal of Psychiatry, [DOI] [Details]
(2019)'Born this way: Hippocampal neurogenesis across the lifespan'
Kozareva, DA;Cryan, JF;Nolan, YM (2019) 'Born this way: Hippocampal neurogenesis across the lifespan'. Aging Cell, [DOI] [Details]
(2019)'Microbiota and the social brain'
E Sherwin, SR Bordenstein, JL Quinn, TG Dinan, JF Cryan (2019) 'Microbiota and the social brain'. 366 [Details]
(2019)'Dietary alpha-lactalbumin alters energy balance, gut microbiota composition and intestinal nutrient transporter expression in high-fat diet fed mice'
Boscaini S.;Cabrera-Rubio R.;Speakman J.;Cotter P.;Cryan J.;Nilaweera K. (2019) 'Dietary alpha-lactalbumin alters energy balance, gut microbiota composition and intestinal nutrient transporter expression in high-fat diet fed mice'. British Journal of Nutrition, [DOI] [Details]
(2019)'Gamma-aminobutyric acid-producing lactobacilli positively affect metabolism and depressive-like behaviour in a mouse model of metabolic syndrome'
Patterson E.;Ryan P.;Wiley N.;Carafa I.;Sherwin E.;Moloney G.;Franciosi E.;Mandal R.;Wishart D.;Tuohy K.;Ross R.;Cryan J.;Dinan T.;Stanton C. (2019) 'Gamma-aminobutyric acid-producing lactobacilli positively affect metabolism and depressive-like behaviour in a mouse model of metabolic syndrome'. Scientific Reports, 9 (1) [DOI] [Details]
(2019)'Increased amygdalar metabotropic glutamate receptor 7 mRNA in a genetic mouse model of impaired fear extinction'
O'Connor, RM;McCafferty, CP;Bravo, JA;Singewald, N;Holmes, A;Cryan, JF (2019) 'Increased amygdalar metabotropic glutamate receptor 7 mRNA in a genetic mouse model of impaired fear extinction'. Journal of Psychopharmacology, 236 :265-272 [DOI] [Details]
(2019)'Gut Reactions: Breaking Down Xenobiotic-Microbiome Interactions'
Clarke G;Sandhu KV;Griffin BT;Dinan TG;Cryan JF;Hyland NP; (2019) 'Gut Reactions: Breaking Down Xenobiotic-Microbiome Interactions'. Pharmacological reviews, 71 (2) [DOI] [Full Text] [Details]
(2019)'From isoniazid to psychobiotics: the gut microbiome as a new antidepressant target'
Butler, MI;Sandhu, K;Cryan, JF;Dinan, TG (2019) 'From isoniazid to psychobiotics: the gut microbiome as a new antidepressant target'. British Journal Of Hospital Medicine (London, England : 2005), 80 [DOI] [Details]
(2019)'Absence of the neurogenesis-dependent nuclear receptor TLX induces inflammation in the hippocampus'
Kozareva, DA;Hueston, CM;O'Leime, CS;Crotty, S;Dockery, P;Cryan, JF;Nolan, YM (2019) 'Absence of the neurogenesis-dependent nuclear receptor TLX induces inflammation in the hippocampus'. Journal of Neuroimmunology, 331 :87-96 [DOI] [Details]
(2019)'Differential effects of psychotropic drugs on microbiome composition and gastrointestinal function'
Cussotto, S;Strain, CR;Fouhy, F;Strain, RG;Peterson, VL;Clarke, G;Stanton, C;Dinan, TG;Cryan, JF (2019) 'Differential effects of psychotropic drugs on microbiome composition and gastrointestinal function'. Journal of Psychopharmacology, 236 :1671-1685 [DOI] [Details]
(2019)'Nutraceuticals to promote neuronal plasticity in response to corticosterone-induced stress in human neuroblastoma cells'
Gite, S;Ross, RP;Kirke, D;Guiheneuf, F;Aussant, J;Stengel, DB;Dinan, TG;Cryan, JF;Stanton, C (2019) 'Nutraceuticals to promote neuronal plasticity in response to corticosterone-induced stress in human neuroblastoma cells'. Nutritional Neuroscience, 22 :551-568 [DOI] [Details]
(2019)'Frontostriatal functional connectivity correlates with repetitive behaviour across autism spectrum disorder and obsessive-compulsive disorder'
Akkermans, SEA;Rheinheimer, N;Bruchhage, MMK;Durston, S;Brandeis, D;Banaschewski, T;Boecker-Schlier, R;Wolf, I;Williams, SCR;Buitelaar, JK;van Rooij, D;Oldehinkel, M;de Ruiter, S;Naaijen, J;Mennes, M;Zwiers, M;Ilbegi, S;Hennissen, L;Glennon, J;van de Vondervoort, I;Kapusta, K;Bielczyk, N;Amiri, H;Havenith, M;Franke, B;Poelmans, G;Bralten, J;Heskes, T;Sokolova, E;Groot, P;Lythgoe, D;Dud, I;Dittmann, R;Mechler, K;Berg, R;Hage, A;Hohmann, S;Ruf, M;Dijkhuizen, R;Blezer, E;van der Marel, K;Pullens, P;Mol, W;van der Toorn, A;Otte, W;van Heijningen, C;Mensen, V;Oranje, B;Mandl, R;Joel, D;Cryan, J;Petryshen, T;Pauls, D;Saito, M;Heckman, A;Bahn, S;Schwalber, A;Auby, P (2019) 'Frontostriatal functional connectivity correlates with repetitive behaviour across autism spectrum disorder and obsessive-compulsive disorder'. Psychological medicine, 49 :2247-2255 [DOI] [Details]
(2019)'Making Sense of … the Microbiome in Psychiatry'
Bastiaanssen TFS;Cowan CSM;Claesson MJ;Dinan TG;Cryan JF; (2019) 'Making Sense of … the Microbiome in Psychiatry'. International Journal of Neuropsychopharmacology, 22 (1) [DOI] [Full Text] [Details]
(2019)'Differential functional selectivity and downstream signaling bias of ghrelin receptor antagonists and inverse agonists'
Ramirez, VT;van Oeffelen, WEPA;Torres-Fuentes, C;Chruscicka, B;Druelle, C;Golubeva, AV;van de Wouw, M;Dinan, TG;Cryan, JF;Schellekens, H (2019) 'Differential functional selectivity and downstream signaling bias of ghrelin receptor antagonists and inverse agonists'. The Faseb Journal, 33 :518-531 [DOI] [Details]
(2019)'Differential effects of adolescent and adult-initiated exercise on cognition and hippocampal neurogenesis'
O'Leary, James D.; Hoban, Alan E.; Murphy, Ashley; O'Leary, Olivia F.; Cryan, John F.; Nolan, Yvonne M. (2019) 'Differential effects of adolescent and adult-initiated exercise on cognition and hippocampal neurogenesis'. Hippocampus, 29 :352-365 [DOI] [Full Text] [Details]
(2019)'Mood and Microbes Gut to Brain Communication in Depression'
Kelly, JR;O'Keane, V;Cryan, JF;Clarke, G;Dinan, TG (2019) 'Mood and Microbes Gut to Brain Communication in Depression'. Gastroenterology Clinics of North America, 48 [DOI] [Details]
(2019)'The Gut Microbiome and Mental Health: What Should We Tell Our Patients?: Le microbiote Intestinal et la Sante Mentale : que Devrions-Nous dire a nos Patients?'
Butler, MI;Morkl, S;Sandhu, KV;Cryan, JF;Dinan, TG (2019) 'The Gut Microbiome and Mental Health: What Should We Tell Our Patients?: Le microbiote Intestinal et la Sante Mentale : que Devrions-Nous dire a nos Patients?'. Canadian journal of psychiatry. Revue canadienne de psychiatrie, [DOI] [Details]
(2019)'Mid-life microbiota crises: middle age is associated with pervasive neuroimmune alterations that are reversed by targeting the gut microbiome'
Boehme, Marcus; van de Wouw, Marcel; Bastiaanssen, Thomaz F. S.; Olavarría-Ramírez, Loreto; Lyons, Katriona; Fouhy, Fiona; Golubeva, Anna V.; Moloney, Gerard M.; Minuto, Chiara; Sandhu, Kiran V.; Scott, Karen A.; Clarke, Gerard; Stanton, Catherine; Dinan, Timothy G.; Schellekens, Harriët; Cryan, John F. (2019) 'Mid-life microbiota crises: middle age is associated with pervasive neuroimmune alterations that are reversed by targeting the gut microbiome'. Molecular Psychiatry,   [DOI] [Full Text] [Details]
(2019)'Differential gene expression in the mesocorticolimbic system of innately high- and low-impulsive rats'
Moloney, Gerard M.; van Oeffelen, Wesley E. P. A.; Ryan, Feargal J.; van de Wouw, Marcel; Cowan, Caitlin; Claesson, Marcus J.; Schellekens, Harriet; Dinan, Timothy G.; Cryan, John F. (2019) 'Differential gene expression in the mesocorticolimbic system of innately high- and low-impulsive rats'. Behavioural Brain Research, 364 :193-204   [DOI] [Full Text] [Details]
(2019)'Short-chain fatty acids and microbiota metabolites attenuate ghrelin receptor signaling'
Torres-Fuentes, C;Golubeva, AV;Zhdanov, AV;Wallace, S;Arboleya, S;Papkovsky, DB;El Aidy, S;Ross, P;Roy, BL;Stanton, C;Dinan, TG;Cryan, JF;Schellekens, H (2019) 'Short-chain fatty acids and microbiota metabolites attenuate ghrelin receptor signaling'. The Faseb Journal, 33 :13546-13559 [DOI] [Details]
(2019)'Host Microbiota Regulates Central Nervous System Serotonin Receptor 2C Editing in Rodents'
van de Wouw, Marcel; Stilling, Roman M.; Peterson, Veronica L.; Ryan, Feargal J.; Hoban, Alan E.; Shanahan, Fergus; Clarke, Gerard; Claesson, Marcus J.; Dinan, Timothy G.; Cryan, John F.; Schellekens, Harriët (2019) 'Host Microbiota Regulates Central Nervous System Serotonin Receptor 2C Editing in Rodents'. ACS Chemical Neuroscience, 10 (9):3953-3960   [DOI] [Full Text] [Details]
(2019)'Monocyte mobilisation, microbiota & mental illness'
van de Wouw, Marcel; Boehme, Marcus; Dinan, Timothy G.; Cryan, John F. (2019) 'Monocyte mobilisation, microbiota & mental illness'. Brain, Behavior, and Immunity, 81 :74-91   [DOI] [Full Text] [Details]
(2019)'Dietary a-lactalbumin alters energy balance, gut microbiota composition and intestinal nutrient transporter expression in high-fat diet-fed mice'
Boscaini, Serena; Cabrera-Rubio, Raul; Speakman, John R.; Cotter, Paul D.; Cryan, John F.; Nilaweera, Kanishka N. (2019) 'Dietary a-lactalbumin alters energy balance, gut microbiota composition and intestinal nutrient transporter expression in high-fat diet-fed mice'. British Journal of Nutrition, 121 (10):1097-1107   [DOI] [Full Text] [Details]
(2019)'Pain bugs: Gut microbiota and pain disorders'
Rea, Kieran; O’Mahony, Siobhain; Dinan, Timothy G.; Cryan, John F. (2019) 'Pain bugs: Gut microbiota and pain disorders'. Current Opinion In Physiology, 11 :97-102   [DOI] [Full Text] [Details]
(2019)'Resilience priming: Translational models for understanding resiliency and adaptation to early life adversity'
Kentner, Amanda C.; Cryan, John F.; Brummelte, Susanne (2019) 'Resilience priming: Translational models for understanding resiliency and adaptation to early life adversity'. Developmental psychobiology, 0 (0)   [DOI] [Full Text] [Details]
(2019)'A role for the orphan nuclear receptor TLX in the interaction between neural precursor cells and microglia'
Kozareva DA, Moloney GM, Hoban EA, Rossini V, Nally K, Cryan JF, Nolan YM. (2019) 'A role for the orphan nuclear receptor TLX in the interaction between neural precursor cells and microglia'. Neuronal Signaling, 3 (1) [DOI] [Details]
(2019)'Natural compulsive-like behaviour in the deer mouse (Peromyscus maniculatus bairdii) is associated with altered gut microbiota composition'
Scheepers, IM;Cryan, JF;Bastiaanssen, TFS;Rea, K;Clarke, G;Jaspan, HB;Harvey, BH;Hemmings, SMJ;Santana, L;van der Sluis, R;Malan-Muller, S;Wolmarans, D (2019) 'Natural compulsive-like behaviour in the deer mouse (Peromyscus maniculatus bairdii) is associated with altered gut microbiota composition'. The European Journal of Neuroscience, [DOI] [Details]
(2019)'Annual Research Review: Critical windows - the microbiota-gut-brain axis in neurocognitive development'
Cowan, CSM;Dinan, TG;Cryan, JF (2019) 'Annual Research Review: Critical windows - the microbiota-gut-brain axis in neurocognitive development'. Journal of child psychology and psychiatry, and allied disciplines, [DOI] [Details]
(2019)'Naturally Derived Polyphenols Protect Against Corticosterone-Induced Changes in Primary Cortical Neurons'
Donoso, F;Ramirez, VT;Golubeva, AV;Moloney, GM;Stanton, C;Dinan, TG;Cryan, JF (2019) 'Naturally Derived Polyphenols Protect Against Corticosterone-Induced Changes in Primary Cortical Neurons'. International Journal of Neuropsychopharmacology, 22 :765-777 [DOI] [Details]
(2019)'Microbiota and neurodevelopmental trajectories: Role of maternal and early-life nutrition'
Codagnone, Martin G.; Stanton, Catherine; O’Mahony, Siobhain M.; Dinan, Timothy G.; Cryan, John F. (2019) 'Microbiota and neurodevelopmental trajectories: Role of maternal and early-life nutrition'. Annals of Nutrition and Metabolism, 74 (2):16-27   [DOI] [Full Text] [Details]
(2019)'The Microbiota-Gut-Brain Axis'
Cryan J.;O'Riordan K.;Cowan C.;Sandhu K.;Bastiaanssen T.;Boehme M.;Codagnone M.;Cussotto S.;Fulling C.;Golubeva A.;Guzzetta K.;Jaggar M.;Long-Smith C.;Lyte J.;Martin J.;Molinero-Perez A.;Moloney G.;Morelli E.;Morillas E.;O'Connor R.;Cruz-Pereira J.;Peterson V.;Rea K.;Ritz N.;Sherwin E.;Spichak S.;Teichman E.;van de Wouw M.;Ventura-Silva A.;Wallace-Fitzsimons S.;Hyland N.;Clarke G.;Dinan T. (2019) 'The Microbiota-Gut-Brain Axis'. Physiological reviews, 99 (4):1877-2013   [DOI] [Full Text] [Details]
(2019)'A comparison of embalming fluids on the structures and properties of tissue in human cadavers'
Balta, JY;Twomey, M;Moloney, F;Duggan, O;Murphy, KP;O'Connor, OJ;Cronin, M;Cryan, JF;Maher, MM;O'Mahony, SM (2019) 'A comparison of embalming fluids on the structures and properties of tissue in human cadavers'. Anatomia, Histologia, Embryologia, 48 :64-73 [DOI] [Details]
(2019)'Without a bug’s life: Germ-free rodents to interrogate microbiotagut-neuroimmune interactions'
Spichak S, Guzzetta KE, O’Leary OF, Clarke G, Dinan TG, Cryan JF (2019) 'Without a bug’s life: Germ-free rodents to interrogate microbiotagut-neuroimmune interactions'. Drug Discovery Today, [Details]
(2019)'Attenuation of Oxytocin and Serotonin 2A Receptor Signaling through Novel Heteroreceptor Formation'
Chruscicka B.;Wallace Fitzsimons S.;Borroto-Escuela D.;Druelle C.;Stamou P.;Nally K.;Dinan T.;Cryan J.;Fuxe K.;Schellekens H. (2019) 'Attenuation of Oxytocin and Serotonin 2A Receptor Signaling through Novel Heteroreceptor Formation'. ACS Chemical Neuroscience, [DOI] [Details]
(2018)'Faecal microRNAs: indicators of imbalance at the host-microbe interface?'
G.M. Moloney,M.F. Viola,A.E. Hoban,T.G. Dinan,J.F. Cryan (2018) 'Faecal microRNAs: indicators of imbalance at the host-microbe interface?'. Beneficial microbes, 0 (0):1-10   [DOI] [Full Text] [Details]
(2018)'Deletion of Tlx and social isolation impairs exercise-induced neurogenesis in the adolescent hippocampus'
Kozareva DA, O'Leary OF, Cryan JF, Nolan YM. (2018) 'Deletion of Tlx and social isolation impairs exercise-induced neurogenesis in the adolescent hippocampus'. Hippocampus, 28 (1):3-11 [Details]
(2018)'Chronic intermittent hypoxia disrupts cardiorespiratory homeostasis and gut microbiota composition in adult male guinea-pigs'
Lucking, EF;O'Connor, KM;Strain, CR;Fouhy, F;Bastiaanssen, TFS;Bums, DP;Golubeva, AV;Stanton, C;Clarke, G;Cryan, JF;O'Halloran, KD (2018) 'Chronic intermittent hypoxia disrupts cardiorespiratory homeostasis and gut microbiota composition in adult male guinea-pigs'. Ebiomedicine, 38 :191-205 [DOI] [Details]
(2018)'A Survey of tooth morphology teaching methods employed in the United Kingdom and Ireland'
Lone M., McKenna JP., Cryan J.F., Downer E.J., Toulouse A. (2018) 'A Survey of tooth morphology teaching methods employed in the United Kingdom and Ireland'. European Journal Of Dental Education : Official Journal Of The Association For Dental Education In Europe, [DOI] [Details]
(2018)'Sustained-release multiparticulates for oral delivery of a novel peptidic ghrelin agonist: Formulation design and in vitro characterization'
Howick, K. and Alam, R. and Chruscicka, B. and Kandil, D. and Fitzpatrick, D. and Ryan, A.M. and Cryan, J.F. and Schellekens, H. and Griffin, B.T. (2018) 'Sustained-release multiparticulates for oral delivery of a novel peptidic ghrelin agonist: Formulation design and in vitro characterization'. International Journal of Pharmaceutics, 536 (1):63-72   [DOI] [Details]
(2018)'Determination of a suitable low-dose abdominopelvic CT protocol using model-based iterative reconstruction through cadaveric study'
Moloney F;Twomey M;Fama D;Balta JY;James K;Kavanagh RG;Moore N;Murphy MJ;O'Mahony SM;Maher MM;Cryan JF;O'Connor OJ; (2018) 'Determination of a suitable low-dose abdominopelvic CT protocol using model-based iterative reconstruction through cadaveric study'. Journal of Medical Imaging and Radiation Oncology, [DOI] [Full Text] [Details]
(2018)'Chronic intermittent hypoxia disrupts cardiorespiratory homeostasis and gut microbiota composition in adult male guinea-pigs'
*Lucking EF, *O'Connor KM, Strain CR, Fouhy F, Bastiaanssen TF, Burns DP, Golubeva AV, Stanton C, Clarke G, Cryan JF, O'Halloran KD (2018) 'Chronic intermittent hypoxia disrupts cardiorespiratory homeostasis and gut microbiota composition in adult male guinea-pigs'. Ebiomedicine, [Details]
(2018)'Understanding neurophobia: Reasons behind impaired understanding and learning of neuroanatomy in cross-disciplinary healthcare students'
Javaid M.A., Chakraborty S., Cryan J.F., Schellekens H., Toulouse A. (2018) 'Understanding neurophobia: Reasons behind impaired understanding and learning of neuroanatomy in cross-disciplinary healthcare students'. Anatomical Sciences Education, 11 (1):81-93   [DOI] [Details]
(2018)'Faecal microRNAs: indicators of imbalance at the host-microbe interface?'
Moloney, GM;Viola, MF;Hoban, AE;Dinan, TG;Cryan, JF (2018) 'Faecal microRNAs: indicators of imbalance at the host-microbe interface?'. Beneficial microbes, 9 :175-183 [DOI] [Details]
(2018)'Satiating effect of a sodium caseinate hydrolysate and its fate in the upper gastrointestinal tract'
Kondrashina, A;Bruen, C;McGrath, B;Murray, B;McCarthy, T;Schellekens, H;Buzoianu, S;Cryan, JF;Kelly, AL;McSweeney, PLH;Lawlor, P;Giblin, L (2018) 'Satiating effect of a sodium caseinate hydrolysate and its fate in the upper gastrointestinal tract'. Journal Of Functional Foods, 49 :306-313 [DOI] [Details]
(2018)'Short-chain fatty acids: microbial metabolites that alleviate stress-induced brain–gut axis alterations'
van de Wouw, Marcel; Boehme, Marcus; Lyte, Joshua M.; Wiley, Niamh; Strain, Conall; O'Sullivan, Orla; Clarke, Gerard; Stanton, Catherine; Dinan, Timothy G.; Cryan, John F. (2018) 'Short-chain fatty acids: microbial metabolites that alleviate stress-induced brain–gut axis alterations'. The Journal of Physiology, 596 (20):4923-4944   [DOI] [Full Text] [Details]
(2018)'Application of a physiologically-based pharmacokinetic model for the prediction of bumetanide plasma and brain concentrations in the neonate'
Donovan, M.D. and Abduljalil, K. and Cryan, J.F. and Boylan, G.B. and Griffin, B.T. (2018) 'Application of a physiologically-based pharmacokinetic model for the prediction of bumetanide plasma and brain concentrations in the neonate'. Biopharmaceutics and Drug Disposition, 39 (3):125-134   [DOI] [Details]
(2018)'Strain differences in the susceptibility to the gut-brain axis and neurobehavioural alterations induced by maternal immune activation in mice'
Morais, LH;Felice, D;Golubeva, AV;Moloney, G;Dinan, TG;Cryan, JF (2018) 'Strain differences in the susceptibility to the gut-brain axis and neurobehavioural alterations induced by maternal immune activation in mice'. Behavioural Pharmacology, 29 :181-198 [DOI] [Details]
(2018)'The microbiome regulates amygdala-dependent fear recall'
Hoban, AE;Stilling, RM;Moloney, G;Shanahan, F;Dinan, TG;Clarke, G;Cryan, JF (2018) 'The microbiome regulates amygdala-dependent fear recall'. Molecular Psychiatry, 23 :1134-1144 [DOI] [Details]
(2018)'Social interaction-induced activation of RNA splicing in the amygdala of microbiome-deficient mice'
Stilling, RM;Moloney, GM;Ryan, FJ;Hoban, AE;Bastiaanssen, TFS;Shanahan, F;Clarke, G;Claesson, MJ;Dinan, TG;Cryan, JF (2018) 'Social interaction-induced activation of RNA splicing in the amygdala of microbiome-deficient mice'. Elife, 7 [DOI] [Details]
(2018)'The Neuroendocrinology of the Microbiota-Gut-Brain Axis: A Behavioural Perspective'
Cussotto, Sofia; Sandhu, Kiran V.; Dinan, Timothy G.; Cryan, John F. (2018) 'The Neuroendocrinology of the Microbiota-Gut-Brain Axis: A Behavioural Perspective'. Frontiers In Neuroendocrinology,   [DOI] [Full Text] [Details]
(2018)'Regulation of behaviour by the nuclear receptor TLX'
O'Leary JD;O'Leary OF;Cryan JF;Nolan YM; (2018) 'Regulation of behaviour by the nuclear receptor TLX'. Genes Brain And Behavior, 17 (3) [DOI] [Details]
(2018)'Gut microbiome correlates with altered striatal dopamine receptor expression in a model of compulsive alcohol seeking'
Jadhav, KS;Peterson, VL;Halfon, O;Ahern, G;Fouhy, F;Stanton, C;Dinan, TG;Cryan, JF;Boutrel, B (2018) 'Gut microbiome correlates with altered striatal dopamine receptor expression in a model of compulsive alcohol seeking'. Neuropharmacology, 141 :249-259 [DOI] [Details]
(2018)'A low-cost touchscreen operant chamber using a Raspberry Pi'
O'Leary, JD;O'Leary, OF;Cryan, JF;Nolan, YM (2018) 'A low-cost touchscreen operant chamber using a Raspberry Pi'. Behavior research methods, 50 :2523-2530 [DOI] [Details]
(2018)'Determination of a suitable low-dose abdominopelvic CT protocol using model-based iterative reconstruction through cadaveric study'
Moloney F, Twomey M, Fama D, Balta JY, James K, Kavanagh RG, Moore N, Murphy MJ, O'Mahony SM, Maher MM, Cryan JF, O'Connor OJ (2018) 'Determination of a suitable low-dose abdominopelvic CT protocol using model-based iterative reconstruction through cadaveric study'. Journal of Medical Imaging and Radiation Oncology, [DOI] [Details]
(2018)'Kynurenine pathway metabolism and neurobiology of treatment-resistant depression: Comparison of multiple ketamine infusions and electroconvulsive therapy'
Allen, A. P.,Naughton, M.,Dowling, J.,Walsh, A.,O'Shea, R.,Shorten, G.,Scott, L.,McLoughlin, D. M.,Cryan, J. F.,Clarke, G.,Dinan, T. D. (2018) 'Kynurenine pathway metabolism and neurobiology of treatment-resistant depression: Comparison of multiple ketamine infusions and electroconvulsive therapy'. Journal of Psychiatric Research,   [DOI] [Full Text] [Details]
(2018)'A casein hydrolysate increases GLP-1 secretion and reduces food intake'
O'Halloran, F;Bruen, C;McGrath, B;Schellekens, H;Murray, B;Cryan, JF;Kelly, AL;McSweeney, PLH;Giblin, L (2018) 'A casein hydrolysate increases GLP-1 secretion and reduces food intake'. Food Chemistry, 252 :303-310 [DOI] [Details]
(2018)'A comparison of embalming fluids on the structures and properties of tissue in human cadavers'
Balta JY, Twomey M, Moloney F, Duggan O, Murphy KP, O'Connor OJ, Cronin M, Cryan JF, Maher MM, O'Mahony SM. (2018) 'A comparison of embalming fluids on the structures and properties of tissue in human cadavers'. Anatomia, Histologia, Embryologia, [DOI] [Details]
(2018)'Chronic interleukin-1 beta in the dorsal hippocampus impairs behavioural pattern separation'
Hueston, CM;O'Leary, JD;Hoban, AE;Kozareva, DA;Pawley, LC;O'Leary, OF;Cryan, JF;Nolan, YM (2018) 'Chronic interleukin-1 beta in the dorsal hippocampus impairs behavioural pattern separation'. Brain Behav Immun, 74 :252-264 [DOI] [Details]
(2018)'TLX is an intrinsic regulator of the negative effects of IL-1 beta on proliferating hippocampal neural progenitor cells'
O'Leime, CS;Kozareva, DA;Hoban, AE;Long-Smith, CM;Cryan, JF;Nolan, YM (2018) 'TLX is an intrinsic regulator of the negative effects of IL-1 beta on proliferating hippocampal neural progenitor cells'. The Faseb Journal, 32 :613-624 [DOI] [Details]
(2018)'Chronic intermittent hypoxia disrupts cardiorespiratory homeostasis and gut microbiota composition in adult male guinea-pigs'
*Lucking EF, O'Connor KM, Strain CR, Fuohy F, Bastiaanssen TF, Burns DP, Golubeva AV, Stanton C, Clarke G, Cryan JF, O'Halloran KD (2018) 'Chronic intermittent hypoxia disrupts cardiorespiratory homeostasis and gut microbiota composition in adult male guinea-pigs'. Ebiomedicine, 38 [DOI] [Details]
(2018)'Chronic Interleukin-1β in the Dorsal Hippocampus Impairs Behavioural Pattern Separation'
Hueston CM, O'Leary JD, Hoban AE, Kozareva DA, Pawley LC, O'Leary OF, Cryan JF, Nolan YM. (2018) 'Chronic Interleukin-1β in the Dorsal Hippocampus Impairs Behavioural Pattern Separation'. Brain Behav Immun, 74 :252-264 [Details]
(2018)'A low-cost touchscreen operant chamber using a Raspberry Pi™'
O'Leary JD, O'Leary OF, Cryan JF, Nolan YM. (2018) 'A low-cost touchscreen operant chamber using a Raspberry Pi™'. Behavioural Research Methods, 50 (6):2523-2530 [DOI] [Details]
(2018)'The Vagus Nerve Modulates BDNF expression and Neurogenesis in the Hippocampus'
O’Leary OF*, Ogbonnaya ES, Felice D, Levone BR, Conroy L, Fitzgerald P, Bravo JA, Forsythe P, Bienenstock J, Dinan TG Cryan JF (2018) 'The Vagus Nerve Modulates BDNF expression and Neurogenesis in the Hippocampus'. European Neuropsychopharmacology, 28 (2):307-331 [Details]
(2018)'Evaluation of an animation tool developed to supplement dental student study of the cranial nerves'
Lone M., McKenna J.P., Vagg T., Cryan J.F., Toulouse A., Downer E.J. (2018) 'Evaluation of an animation tool developed to supplement dental student study of the cranial nerves'. European Journal Of Dental Education : Official Journal Of The Association For Dental Education In Europe, [DOI] [Details]
(2018)'Understanding neurophobia: Reasons behind impaired understanding and learning of neuroanatomy in cross-disciplinary healthcare students'
Javaid, MA;Chakraborty, S;Cryan, JF;Schellekens, H;Toulouse, A (2018) 'Understanding neurophobia: Reasons behind impaired understanding and learning of neuroanatomy in cross-disciplinary healthcare students'. Anatomical Sciences Education, 11 :81-93 [DOI] [Details]
(2018)'Post-weaning social isolation of rats leads to long-term disruption of the gut microbiota-immune-brain axis'
Doherty, FD;O'Mahony, SM;Peterson, VL;O'Sullivan, O;Crispie, F;Cotter, PD;Wigmore, P;King, MV;Cryan, JF;Fone, KCF (2018) 'Post-weaning social isolation of rats leads to long-term disruption of the gut microbiota-immune-brain axis'. Brain Behav Immun, 68 :261-273 [DOI] [Details]
(2018)'The vagus nerve modulates BDNF expression and neurogenesis in the hippocampus'
O'Leary, OF;Ogbonnaya, ES;Felice, D;Levone, BR;Conroy, LC;Fitzgerald, P;Bravo, JA;Forsythe, P;Bienenstock, J;Dinan, TG;Cryan, JF (2018) 'The vagus nerve modulates BDNF expression and neurogenesis in the hippocampus'. European Neuropsychopharmacology, 28 :307-316 [DOI] [Details]
(2018)'Elucidation of the Neural Circuits Activated by a GABAB Receptor Positive Modulator: Relevance to Anxiety'
Pizzo R*, O’Leary OF* and Cryan JF (2018) 'Elucidation of the Neural Circuits Activated by a GABAB Receptor Positive Modulator: Relevance to Anxiety'. Neuropharmacology, 136 (Pt A):129-145 [Details]
(2018)'Elucidation of the neural circuits activated by a GABA(B) receptor positive modulator: Relevance to anxiety'
Pizzo, R;O'Leary, OE;Cryan, JF (2018) 'Elucidation of the neural circuits activated by a GABA(B) receptor positive modulator: Relevance to anxiety'. Neuropharmacology, 136 :129-145 [DOI] [Details]
(2018)'A dairy-derived ghrelinergic hydrolysate modulates food intake in vivo'
Howick, K. and Wallace-Fitzsimons, S.E. and Kandil, D. and Chruscicka, B. and Calis, M. and Murphy, E. and Murray, B.A. and Fernandez, A. and Barry, K.M. and Kelly, P.M. and Ryan, A.M. and Cryan, J.F. and Griffin, B.T. and Schellekens, H. (2018) 'A dairy-derived ghrelinergic hydrolysate modulates food intake in vivo'. International Journal of Molecular Sciences, 19 (9)   [DOI] [Details]
(2017)'Deficiency of essential dietary n-3 PUFA disrupts the caecal microbiome and metabolome in mice'
Robertson, Ruairi C.; Seira Oriach, Clara; Murphy, Kiera; Moloney, Gerard M.; Cryan, John F.; Dinan, Timothy G.; Ross, R. Paul; Stanton, Catherine (2017) 'Deficiency of essential dietary n-3 PUFA disrupts the caecal microbiome and metabolome in mice'. British Journal of Nutrition, 118 (11):959-970   [DOI] [Full Text] [Details]
(2017)'ADOLESCENT SOCIAL ISOLATION STRESS UNMASKS THE COMBINED EFFECTS OF ADOLESCENT EXERCISE AND ADULT INFLAMMATION ON HIPPOCAMPAL NEUROGENESIS AND BEHAVIOR'
Hueston, CM;Cryan, JF;Nolan, YM (2017) 'ADOLESCENT SOCIAL ISOLATION STRESS UNMASKS THE COMBINED EFFECTS OF ADOLESCENT EXERCISE AND ADULT INFLAMMATION ON HIPPOCAMPAL NEUROGENESIS AND BEHAVIOR'. Neuroscience, 365 :226-236 [DOI] [Details]
(2017)'Drunk bugs: Chronic vapour alcohol exposure induces marked changes in the gut microbiome in mice'
Peterson, Veronica L.; Jury, Nicholas J.; Cabrera-Rubio, Raúl; Draper, Lorraine A.; Crispie, Fiona; Cotter, Paul D.; Dinan, Timothy G.; Holmes, Andrew; Cryan, John F. (2017) 'Drunk bugs: Chronic vapour alcohol exposure induces marked changes in the gut microbiome in mice'. Behavioural Brain Research, 323 :172-176   [DOI] [Full Text] [Details]
(2017)'Targeting the Microbiota-Gut-Brain Axis: Prebiotics Have Anxiolytic and Antidepressant-like Effects and Reverse the Impact of Chronic Stress in Mice'
Burokas, Aurelijus; Arboleya, Silvia; Moloney, Rachel D.; Peterson, Veronica L.; Murphy, Kiera; Clarke, Gerard; Stanton, Catherine; Dinan, Timothy G.; Cryan, John F. (2017) 'Targeting the Microbiota-Gut-Brain Axis: Prebiotics Have Anxiolytic and Antidepressant-like Effects and Reverse the Impact of Chronic Stress in Mice'. Biological Psychiatry, :1-16 [DOI] [Full Text] [Details]
(2017)'A psychology of the human brain–gut–microbiome axis'
Allen, Andrew P.; Dinan, Timothy G.; Clarke, Gerard; Cryan, John F. (2017) 'A psychology of the human brain–gut–microbiome axis'. Social And Personality Psychology Compass, 11 (4) [DOI] [Full Text] [Details]
(2017)'Aroma compound diacetyl suppresses glucagon-like peptide-1 production and secretion in STC-1 cells'
McCarthy, Triona; Bruen, Christine; O'Halloran, Fiona; Schellekens, Harriet; Kilcawley, Kieran; Cryan, John F.; Giblin, Linda (2017) 'Aroma compound diacetyl suppresses glucagon-like peptide-1 production and secretion in STC-1 cells'. Food Chemistry, 228 :35-42 [DOI] [Full Text] [Details]
(2017)'Microbial regulation of hippocampal miRNA expression: Implications for transcription of kynurenine pathway enzymes'
Moloney, Gerard M.; O’Leary, Olivia F.; Salvo-Romero, Eloisa; Desbonnet, Lieve; Shanahan, Fergus; Dinan, Timothy G.; Clarke, Gerard; Cryan, John F. (2017) 'Microbial regulation of hippocampal miRNA expression: Implications for transcription of kynurenine pathway enzymes'. Behavioural Brain Research, 334 :50-54   [DOI] [Details]
(2017)'Revisiting Metchnikoff: Age-related alterations in microbiota-gut-brain axis in the mouse'
Scott, Karen A.; Ida, Masayuki; Peterson, Veronica L.; Prenderville, Jack A.; Moloney, Gerard M.; Izumo, Takayuki; Murphy, Kiera; Murphy, Amy; Ross, R. Paul; Stanton, Catherine; Dinan, Timothy G.; Cryan, John F. (2017) 'Revisiting Metchnikoff: Age-related alterations in microbiota-gut-brain axis in the mouse'. Brain, Behavior, and Immunity, [DOI] [Full Text] [Details]
(2017)'Gutsy moves: The amygdala as a critical node in microbiota to brain signaling'
Cowan, Caitlin S. M.; Hoban, Alan E.; Ventura-Silva, Ana Paula; Dinan, Timothy G.;Clarke, Gerard;Cryan, John F. (2017) 'Gutsy moves: The amygdala as a critical node in microbiota to brain signaling'. Bioessays,   [DOI] [Full Text] [Details]
(2017)'Targeting the Microbiota-Gut-Brain Axis: Prebiotics Have Anxiolytic and Antidepressant-like Effects and Reverse the Impact of Chronic Stress in Mice'
Burokas, A. and Arboleya, S. and Moloney, R. D. and Peterson, V. L. and Murphy, K. and Clarke, G. and Stanton, C. and Dinan, T. G. and Cryan, J. F. (2017) 'Targeting the Microbiota-Gut-Brain Axis: Prebiotics Have Anxiolytic and Antidepressant-like Effects and Reverse the Impact of Chronic Stress in Mice'. Biological Psychiatry, 82 (7):472-487   [DOI] [Details]
(2017)'Microbial regulation of microRNA expression in the amygdala and prefrontal cortex'
Hoban, A. E. and Stilling, R. M. and Moloney, G. M. and Moloney, R. D. and Shanahan, F. and Dinan, T. G. and Cryan, J. F. and Clarke, G. (2017) 'Microbial regulation of microRNA expression in the amygdala and prefrontal cortex'. Microbiome, 5   [DOI] [Details]
(2017)'BEHAVIOURAL AND NEUROCHEMICAL CONSEQUENCES OF CHRONIC GUT MICROBIOTA DEPLETION DURING ADULTHOOD IN THE RAT (vol 339, pg 463, 2016)'
Hoban, A. E. and Moloney, R. D. and Golubeva, A. V. and Neufeld, K. A. M. and O'Sullivan, O. and Patterson, E. and Stanton, C. and Dinan, T. G. and Clarke, G. and Cryan, J. F. (2017) 'BEHAVIOURAL AND NEUROCHEMICAL CONSEQUENCES OF CHRONIC GUT MICROBIOTA DEPLETION DURING ADULTHOOD IN THE RAT (vol 339, pg 463, 2016)'. Neuroscience, 344 :418-418   [DOI] [Details]
(2017)'Nuclear deterrents: Intrinsic regulators of IL-1ß-induced effects on hippocampal neurogenesis'
O'Léime CS;Cryan JF;Nolan YM; (2017) 'Nuclear deterrents: Intrinsic regulators of IL-1ß-induced effects on hippocampal neurogenesis'. Brain Behav Immun, 66 [DOI] [Details]
(2017)'Visceral pain: Role of the microbiome-gut-brain axis'
Rea K.;O'Mahony S.;Dinan T.;Cryan J. (2017) 'Visceral pain: Role of the microbiome-gut-brain axis'. The Biochemist, 39 (2):6-9 [Details]
(2017)'Microbial regulation of microRNA expression in the amygdala and prefrontal cortex'
Hoban, AE;Stilling, RM;Moloney, GM;Moloney, RD;Shanahan, F;Dinan, TG;Cryan, JF;Clarke, G (2017) 'Microbial regulation of microRNA expression in the amygdala and prefrontal cortex'. Microbiome, 5 [DOI] [Details]
(2017)'Assessment of Thiel-embalmed cadavers as a teaching tool for oral anatomy and local anesthesia'
Lone M., McKenna J.P., Balta J.Y., O'Mahony S.M., Cryan J.F., Downer E.J., Toulouse A. (2017) 'Assessment of Thiel-embalmed cadavers as a teaching tool for oral anatomy and local anesthesia'. Journal of Dental Education, 81 (4):420-427   [DOI] [Details]
(2017)'The hippocampus and dorsal raphe nucleus are key brain areas associated with the antidepressant effects of lithium augmentation of desipramine'
Cussotto, S;Cryan, JF;O'Leary, OF (2017) 'The hippocampus and dorsal raphe nucleus are key brain areas associated with the antidepressant effects of lithium augmentation of desipramine'. Neuroscience Letters, 648 :14-20 [DOI] [Details]
(2017)'The gut microbiota as a key regulator of visceral pain'
Mahony, SMO;Dinan, TG;Cryan, JF (2017) 'The gut microbiota as a key regulator of visceral pain'. Pain, 158 :19-28 [DOI] [Details]
(2017)'The hippocampus and dorsal raphe nucleus are key brain areas associated with the antidepressant effects of lithium augmentation of desipramine'
Cussotto S, Cryan JF, O’Leary OF (2017) 'The hippocampus and dorsal raphe nucleus are key brain areas associated with the antidepressant effects of lithium augmentation of desipramine'. Neuroscience Letters, 648 :14-20 [DOI] [Details]
(2017)'Microbial regulation of hippocampal miRNA expression: Implications for transcription of kynurenine pathway enzymes'
Moloney GM, O'Leary OF, Salvo-Romero E, Desbonnet L, Shanahan F, Dinan TG, Clarke G, Cryan JF. (2017) 'Microbial regulation of hippocampal miRNA expression: Implications for transcription of kynurenine pathway enzymes'. Behavioural Brain Research, 334 :50-54 [Details]
(2017)'Targeted drug delivery via folate receptors for the treatment of brain cancer: Can the promise deliver?'
Guo J., Schlich M., Cryan JF., O’Driscoll CM (2017) 'Targeted drug delivery via folate receptors for the treatment of brain cancer: Can the promise deliver?'. Journal of Pharmaceutical Science, 106 :3413-3420 [Details]
(2017)'Microbiota regulates visceral pain in the mouse'
Luczynski, P;Tramullas, M;Viola, M;Shanahan, F;Clarke, G;O'Mahony, S;Dinan, TG;Cryan, JF (2017) 'Microbiota regulates visceral pain in the mouse'. Elife, 6 [DOI] [Details]
(2017)'BEHAVIOURAL AND NEUROCHEMICAL CONSEQUENCES OF CHRONIC GUT MICROBIOTA DEPLETION DURING ADULTHOOD IN THE RAT (vol 339, pg 463, 2016)'
Hoban, AE;Moloney, RD;Golubeva, AV;Neufeld, KAM;O'Sullivan, O;Patterson, E;Stanton, C;Dinan, TG;Clarke, G;Cryan, JF (2017) 'BEHAVIOURAL AND NEUROCHEMICAL CONSEQUENCES OF CHRONIC GUT MICROBIOTA DEPLETION DURING ADULTHOOD IN THE RAT (vol 339, pg 463, 2016)'. Neuroscience, 344 :418-418 [DOI] [Details]
(2017)'Assessing radiological images of human cadavers: Is there an effect of different embalming solutions?'
Balta, JY;Twomey, M;Moloney, F;O'Connor, OJ;Murphy, KP;Cronin, M;Cryan, JF;Maher, MM;O'Mahony, SM (2017) 'Assessing radiological images of human cadavers: Is there an effect of different embalming solutions?'. Journal Of Forensic Radiology And Imaging, 11 :40-46 [DOI] [Full Text] [Details]
(2017)'Intervention strategies for cesarean section- induced alterations in the microbiota-gut-brain axis'
Moya-Pérez A.;Luczynski P.;Renes I.;Wang S.;Borre Y.;Ryan C.;Knol J.;Stanton C.;Dinan T.;Cryan J. (2017) 'Intervention strategies for cesarean section- induced alterations in the microbiota-gut-brain axis'. Nutrition Reviews, 75 (4):225-240 [DOI] [Details]
(2017)'Sustained-release multiparticulates for oral delivery of a novel peptidic ghrelin agonist: Formulation design and in vitro characterization'
Howick K;Alam R;Chruscicka B;Kandil D;Fitzpatrick D;Ryan AM;Cryan JF;Schellekens H;Griffin BT; (2017) 'Sustained-release multiparticulates for oral delivery of a novel peptidic ghrelin agonist: Formulation design and in vitro characterization'. International Journal of Pharmaceutics, 536 (1) [DOI] [Details]
(2017)'Microbiota-related Changes in Bile Acid & Tryptophan Metabolism are Associated with Gastrointestinal Dysfunction in a Mouse Model of Autism'
Golubeva AV;Joyce SA;Moloney G;Burokas A;Sherwin E;Arboleya S;Flynn I;Khochanskiy D;Moya-Pérez A;Peterson V;Rea K;Murphy K;Makarova O;Buravkov S;Hyland NP;Stanton C;Clarke G;Gahan CGM;Dinan TG;Cryan JF; (2017) 'Microbiota-related Changes in Bile Acid & Tryptophan Metabolism are Associated with Gastrointestinal Dysfunction in a Mouse Model of Autism'. Ebiomedicine, 24 [DOI] [Details]
(2017)'The microbiota-gut-brain axis as a key regulator of neural function and the stress response: Implications for human and animal health'
Wiley, NC;Dinan, TG;Ross, RP;Stanton, C;Clarke, G;Cryan, JF (2017) 'The microbiota-gut-brain axis as a key regulator of neural function and the stress response: Implications for human and animal health'. Journal of Animal Science, 95 :3225-3246 [DOI] [Details]
(2017)'Epistatic and Independent Effects on Schizophrenia-Related Phenotypes Following Co-disruption of the Risk Factors Neuregulin-1 x DISC1'
O'Tuathaigh, CMP;Fumagalli, F;Desbonnet, L;Perez-Branguli, F;Moloney, G;Loftus, S;O'Leary, C;Petit, E;Cox, R;Tighe, O;Clarke, G;Lai, D;Harvey, RP;Cryan, JF;Mitchell, KJ;Dinan, TG;Riva, MA;Waddington, JL (2017) 'Epistatic and Independent Effects on Schizophrenia-Related Phenotypes Following Co-disruption of the Risk Factors Neuregulin-1 x DISC1'. Schizophrenia bulletin, 43 :214-225 [DOI] [Details]
(2017)'Drunk bugs: Chronic vapour alcohol exposure induces marked changes in the gut microbiome in mice'
Peterson, VL;Jury, NJ;Cabrera-Rubio, R;Draper, LA;Crispie, F;Cotter, PD;Dinan, TG;Holmes, A;Cryan, JF (2017) 'Drunk bugs: Chronic vapour alcohol exposure induces marked changes in the gut microbiome in mice'. Behavioural Brain Research, 323 :172-176 [DOI] [Details]
(2017)'Gut instincts: microbiota as a key regulator of brain development, ageing and neurodegeneration'
Dinan T.;Cryan J. (2017) 'Gut instincts: microbiota as a key regulator of brain development, ageing and neurodegeneration'. Journal of Physiology-London, 595 (2):489-503 [DOI] [Details]
(2017)'Whey protein effects on energy balance link the intestinal mechanisms of energy absorption with adiposity and hypothalamic neuropeptide gene expression'
Nilaweera, KN;Cabrera-Rubio, R;Speakman, JR;O'Connor, PM;McAuliffe, A;Guinane, CM;Lawton, EM;Crispie, F;Aguilera, M;Stanley, M;Boscaini, S;Joyce, S;Melgar, S;Cryan, JF;Cotter, PD (2017) 'Whey protein effects on energy balance link the intestinal mechanisms of energy absorption with adiposity and hypothalamic neuropeptide gene expression'. American Journal of Physiology (Endocrinology and Metabolism), 313 :1-11 [DOI] [Details]
(2017)'Blunted 5-HT1A receptor-mediated responses and antidepressant-like behavior in mice lacking the GABA(B1a) but not GABA(B1b) subunit isoforms'
Jacobson, LH;Hoyer, D;Fehlmann, D;Bettler, B;Kaupmann, K;Cryan, JF (2017) 'Blunted 5-HT1A receptor-mediated responses and antidepressant-like behavior in mice lacking the GABA(B1a) but not GABA(B1b) subunit isoforms'. Journal of Psychopharmacology, 234 :1511-1523 [DOI] [Details]
(2017)'Recombinant Incretin-Secreting Microbe Improves Metabolic Dysfunction in High-Fat Diet Fed Rodents'
Ryan, PM;Patterson, E;Kent, RM;Stack, H;O'Connor, PM;Murphy, K;Peterson, VL;Mandal, R;Wishart, DS;Dinan, TG;Cryan, JF;Seeley, RJ;Stanton, C;Ross, RP (2017) 'Recombinant Incretin-Secreting Microbe Improves Metabolic Dysfunction in High-Fat Diet Fed Rodents'. Scientific Reports, 7 [DOI] [Details]
(2017)'Omega-3 polyunsaturated fatty acids critically regulate behaviour and gut microbiota development in adolescence and adulthood'
Robertson, RC;Oriach, CS;Murphy, K;Moloney, GM;Cryan, JF;Dinan, TG;Ross, RP;Stanton, C (2017) 'Omega-3 polyunsaturated fatty acids critically regulate behaviour and gut microbiota development in adolescence and adulthood'. Brain Behav Immun, 59 :21-37 [DOI] [Details]
(2017)'Assessment of Thiel-Embalmed Cadavers as a Teaching Tool for Oral Anatomy and Local Anesthesia'
Lone M, McKenna JP, Balta JY, O'Mahony SM, Cryan JF, Downer EJ, Toulouse A (2017) 'Assessment of Thiel-Embalmed Cadavers as a Teaching Tool for Oral Anatomy and Local Anesthesia'. Journal of Dental Education, 81 (4):420-426 [DOI] [Details]
(2017)'Bifidobacterium infantis 35624 and other probiotics in the management of irritable bowel syndrome. Strain specificity, symptoms, and mechanisms'
Allen, AP;Clarke, G;Cryan, JF;Quigley, EMM;Dinan, TG (2017) 'Bifidobacterium infantis 35624 and other probiotics in the management of irritable bowel syndrome. Strain specificity, symptoms, and mechanisms'. Current medical research and opinion, 33 :1349-1351 [DOI] [Details]
(2017)'Corrigendum to “Behavioural and neurochemical consequences of chronic gut microbiota depletion during adulthood in the rat” [Neuroscience 339 (2016) 463–477]'
Hoban, Alan E.; Moloney, Rachel D.; Golubeva, Anna V.; McVey Neufeld, Karen A.; O'Sullivan, Orla; Patterson, Elaine; Stanton, Catherine; Dinan, Timothy G.; Clarke, Gerard; Cryan, John F. (2017) 'Corrigendum to “Behavioural and neurochemical consequences of chronic gut microbiota depletion during adulthood in the rat” [Neuroscience 339 (2016) 463–477]'. Neuroscience, 344 :418-418   [DOI] [Details]
(2016)'Microbiome to brain: Unravelling the multidirectional axes of communication'
El Aidy S.;Stilling R.;Dinan T.;Cryan J. (2016) 'Microbiome to brain: Unravelling the multidirectional axes of communication'. Advances In Experimental Medicine and Biology, 874 :301-336 [DOI] [Details]
(2016)'Targeting the GABAB receptor for the treatment of depression and anxiety disorders'
Felice D.;O’Leary O.;Cryan J. (2016) 'Targeting the GABAB receptor for the treatment of depression and anxiety disorders'. Receptors, 29 :219-250 [DOI] [Details]
(2016)'Growing up in a bubble: Using germ-free animals to assess the influence of the gut microbiota on brain and behavior'
Luczynski P.;Neufeld K.;Oriach C.;Clarke G.;Dinan T.;Cryan J. (2016) 'Growing up in a bubble: Using germ-free animals to assess the influence of the gut microbiota on brain and behavior'. International Journal of Neuropsychopharmacology, 19 (8):1-17 [DOI] [Details]
(2016)'Stress and the Microbiota-Gut-Brain Axis in Visceral Pain: Relevance to Irritable Bowel Syndrome'
Moloney, R. D. and Johnson, A. C. and O'Mahony, S. M. and Dinan, T. G. and Meerveld, B. G. V. and Cryan, J. F. (2016) 'Stress and the Microbiota-Gut-Brain Axis in Visceral Pain: Relevance to Irritable Bowel Syndrome'. Cns Neuroscience & Therapeutics, 22 (2):102-117   [DOI] [Details]
(2016)'Metabotropic Glutamate Receptors in Central Nervous System Diseases'
Golubeva, A. V. and Moloney, R. D. and O'Connor, R. M. and Dinan, T. G. and Cryan, J. F. (2016) 'Metabotropic Glutamate Receptors in Central Nervous System Diseases'. Current Drug Targets, 17 (5):538-616   [DOI] [Details]
(2016)'Estrous cycle influences excitatory amino acid transport and visceral pain sensitivity in the rat: effects of early-life stress'
Moloney, R. D. and Sajjad, J. and Foley, T. and Felice, V. D. and Dinan, T. G. and Cryan, J. F. and O'Mahony, S. M. (2016) 'Estrous cycle influences excitatory amino acid transport and visceral pain sensitivity in the rat: effects of early-life stress'. Biology of Sex Differences, 7   [DOI] [Details]
(2016)'Effect of P-Glycoprotein Inhibition on the Brain Distribution and Antidepressant-Like Activity of Escitalopram in Rodents'
O'Brien, FE;O'Connor, RM;Clarke, G;Dinan, TG;Griffin, BT;Cryan, JF (2016) 'Effect of P-Glycoprotein Inhibition on the Brain Distribution and Antidepressant-Like Activity of Escitalopram in Rodents'. IRISH JOURNAL OF MEDICAL SCIENCE, 185 :36-36 [Details]
(2016)'Influence of GABA and GABA-producing Lactobacillus brevis DPC 6108 on the development of diabetes in a streptozotocin rat model'
Marques, TM;Patterson, E;Wall, R;Sullivan, OO;Fitzgerald, GF;Cotter, PD;Dinan, TG;Cryan, JF;Ross, RP;Stanton, C (2016) 'Influence of GABA and GABA-producing Lactobacillus brevis DPC 6108 on the development of diabetes in a streptozotocin rat model'. Beneficial microbes, 7 :409-420 [DOI] [Details]
(2016)'Microbiome in brain function and mental health'
Kennedy, PJ;Murphy, AB;Cryan, JF;Ross, PR;Dinan, TG;Stanton, C (2016) 'Microbiome in brain function and mental health'. Trends In Food Science and Technology, 57 :289-301 [DOI] [Details]
(2016)'BEHAVIOURAL AND NEUROCHEMICAL CONSEQUENCES OF CHRONIC GUT MICROBIOTA DEPLETION DURING ADULTHOOD IN THE RAT'
Hoban, AE;Moloney, RD;Golubeva, AV;Neufeld, KAM;O'Sullivan, O;Patterson, E;Stanton, C;Dinan, TG;Clarke, G;Cryan, JF (2016) 'BEHAVIOURAL AND NEUROCHEMICAL CONSEQUENCES OF CHRONIC GUT MICROBIOTA DEPLETION DURING ADULTHOOD IN THE RAT'. Neuroscience, 339 :463-477 [DOI] [Details]
(2016)'Probiotic modulation of the microbiota-gut-brain axis and behaviour in zebrafish'
Borrelli, L;Aceto, S;Agnisola, C;De Paolo, S;Dipineto, L;Stilling, RM;Dinan, TG;Cryan, JF;Menna, LF;Fioretti, A (2016) 'Probiotic modulation of the microbiota-gut-brain axis and behaviour in zebrafish'. Scientific Reports, 6 [DOI] [Details]
(2016)'May the Force Be With You: The Light and Dark Sides of the Microbiota-Gut-Brain Axis in Neuropsychiatry'
Sherwin, E;Sandhu, KV;Dinan, TG;Cryan, JF (2016) 'May the Force Be With You: The Light and Dark Sides of the Microbiota-Gut-Brain Axis in Neuropsychiatry'. Cns Drugs, 30 :1019-1041 [DOI] [Details]
(2016)'Obesity Takes Its Toll on Visceral Pain: High-Fat Diet Induces Toll-Like Receptor 4-Dependent Visceral Hypersensitivity'
Tramullas, M;Finger, BC;Dinan, TG;Cryan, JF (2016) 'Obesity Takes Its Toll on Visceral Pain: High-Fat Diet Induces Toll-Like Receptor 4-Dependent Visceral Hypersensitivity'. Plos One, 11 [DOI] [Details]
(2016)'Effect of P-Glycoprotein Inhibition on the Brain Distribution and Antidepressant-Like Activity of Escitalopram in Rodents'
O'Brien, FE,O'Connor, RM,Clarke, G,Dinan, TG,Griffin, BT,Cryan, JF (2016) 'Effect of P-Glycoprotein Inhibition on the Brain Distribution and Antidepressant-Like Activity of Escitalopram in Rodents'. Irish journal of medical science, 185 :36-36 [Details]
(2016)'SEX-DEPENDENT ACTIVITY OF THE SPINAL EXCITATORY AMINO ACID TRANSPORTER: ROLE OF ESTROUS CYCLE'
Sajjad, J;Felice, VD;Golubeva, AV;Cryan, JF;O'Mahony, SM (2016) 'SEX-DEPENDENT ACTIVITY OF THE SPINAL EXCITATORY AMINO ACID TRANSPORTER: ROLE OF ESTROUS CYCLE'. Neuroscience, 333 :311-319 [DOI] [Details]
(2016)'Obstetrical Mode of Delivery and Childhood Behavior and Psychological Development in a British Cohort'
Curran, EA;Cryan, JF;Kenny, LC;Dinan, TG;Kearney, PM;Khashan, AS (2016) 'Obstetrical Mode of Delivery and Childhood Behavior and Psychological Development in a British Cohort'. Journal of Autism and Developmental Disorders, 46 :603-614 [DOI] [Details]
(2016)'MicroRNAs as biomarkers for major depression: a role for let-7b and let-7c'
Gururajan A;Naughton ME;Scott KA;O'Connor RM;Moloney G;Clarke G;Dowling J;Walsh A;Ismail F;Shorten G;Scott L;McLoughlin DM;Cryan JF;Dinan TG; (2016) 'MicroRNAs as biomarkers for major depression: a role for let-7b and let-7c'. Translational Psychiatry, 6 (8) [DOI] [Details]
(2016)'Getting the Hologenome Concept Right: an Eco-Evolutionary Framework for Hosts and Their Microbiomes'
Theis, KR;Dheilly, NM;Klassen, JL;Brucker, RM;Baines, JF;Bosch, TCG;Cryan, JF;Gilbert, SF;Goodnight, CJ;Lloyd, EA;Sapp, J;Vandenkoornhuyse, P;Zilber-Rosenberg, I;Rosenberg, E;Bordenstein, SR (2016) 'Getting the Hologenome Concept Right: an Eco-Evolutionary Framework for Hosts and Their Microbiomes'. Msystems, 1 [DOI] [Details]
(2016)'Adult microbiota-deficient mice have distinct dendritic morphological changes: differential effects in the amygdala and hippocampus'
Luczynski, P;Whelan, SO;O'Sullivan, C;Clarke, G;Shanahan, F;Dinan, TG;Cryan, JF (2016) 'Adult microbiota-deficient mice have distinct dendritic morphological changes: differential effects in the amygdala and hippocampus'. The European Journal of Neuroscience, 44 :2654-2666 [DOI] [Details]
(2016)'In vitro bidirectional permeability studies identify pharmacokinetic limitations of NKCC1 inhibitor bumetanide'
Donovan, M. D.,Schellekens, H.,Boylan, G. B.,Cryan, J. E.,Griffin, B. T. (2016) 'In vitro bidirectional permeability studies identify pharmacokinetic limitations of NKCC1 inhibitor bumetanide'. European Journal of PharmacologyEuropean Journal of Pharmacology, 770 :117-125   [Details]
(2016)'Treating disorders of the neonatal central nervous system: pharmacokinetic and pharmacodynamic considerations with a focus on antiepileptics'
Donovan, M. D.,Boylan, G. B.,Murray, D. M.,Cryan, J. F.,Griffin, B. T. (2016) 'Treating disorders of the neonatal central nervous system: pharmacokinetic and pharmacodynamic considerations with a focus on antiepileptics'. British Journal of Clinical Pharmacology, 81 (11):62-77   [Details]
(2016)'Influence of GABA and GABA-producing Lactobacillus brevis DPC 6108 on the development of diabetes in a streptozotocin rat model'
Marques TM, Patterson E, Wall R, O'Sullivan O, Fitzgerald GF, Cotter PD, Dinan TG, Cryan JF, Ross RP, Stanton C. (2016) 'Influence of GABA and GABA-producing Lactobacillus brevis DPC 6108 on the development of diabetes in a streptozotocin rat model'. Beneficial microbes, 25 :1-12 [Details]
(2016)'The Trier Social Stress Test: principles and practice'
Allen, Andrew P.; Kennedy, Paul J.; Dockray, Samantha; Cryan, John F.; Dinan, Timothy G.; Clarke, Gerard (2016) 'The Trier Social Stress Test: principles and practice'. Neurobiology of Stress, [DOI] [Full Text] [Details]
(2016)'Quantitative analysis of mucosal oxygenation using ex vivo imaging of healthy and inflamed mammalian colon tissue'
Zhdanov AV;Okkelman IA;Golubeva AV;Doerr B;Hyland NP;Melgar S;Shanahan F;Cryan JF;Papkovsky DB; (2016) 'Quantitative analysis of mucosal oxygenation using ex vivo imaging of healthy and inflamed mammalian colon tissue'. Cellular and Molecular Life Sciences, [DOI] [Details]
(2016)'Brain-gut-microbiota axis: challenges for translation in psychiatry'
Kelly, JR,Clarke, G,Cryan, JF,Dinan, TG (2016) 'Brain-gut-microbiota axis: challenges for translation in psychiatry'. Annals Of Epidemiology, 26 :366-372 [DOI] [Details]
(2016)'Transferring the blues: Depression-associated gut microbiota induces neurobehavioural changes in the rat'
Kelly, JR,Borre, Y,Brien, CO,Patterson, E,El Aidy, S,Deane, J,Kennedy, PJ,Beers, S,Scott, K,Moloney, G,Hoban, AE,Scott, L,Fitzgerald, P,Ross, P,Stanton, C,Clarke, G,Cryan, JF,Dinan, TG (2016) 'Transferring the blues: Depression-associated gut microbiota induces neurobehavioural changes in the rat'. Journal of Psychiatric Research, 82 :109-118 [DOI] [Details]
(2016)'11-beta hydroxysteroid type 1 knockout mice display an antidepressant-like phenotype in the forced swim test'
Slattery, DA,Uzunov, DP,Cryan, JF (2016) '11-beta hydroxysteroid type 1 knockout mice display an antidepressant-like phenotype in the forced swim test'. Acta Neuropsychiatrica, 28 :55-60 [DOI] [Details]
(2016)'Effect of P-Glycoprotein Inhibition on the Brain Distribution and Antidepressant-Like Activity of Escitalopram in Rodents'
O'Brien, F. E.,O'Connor, R. M.,Clarke, G.,Dinan, T. G.,Griffin, B. T.,Cryan, J. F. (2016) 'Effect of P-Glycoprotein Inhibition on the Brain Distribution and Antidepressant-Like Activity of Escitalopram in Rodents'. Irish Journal of Medical Science, 185 [Details]
(2016)'Treating disorders of the neonatal central nervous system: pharmacokinetic and pharmacodynamic considerations with a focus on antiepileptics'
Donovan MD;Boylan GB;Murray DM;Cryan JF;Griffin BT; (2016) 'Treating disorders of the neonatal central nervous system: pharmacokinetic and pharmacodynamic considerations with a focus on antiepileptics'. British Journal of Clinical Pharmacology, 81 (1) [DOI] [Details]
(2016)'Birth by Caesarean Section and the Risk of Adult Psychosis: A Population-Based Cohort Study'
O'Neill, SM;Curran, EA;Dalman, C;Kenny, LC;Kearney, PM;Clarke, G;Cryan, JF;Dinan, TG;Khashan, AS (2016) 'Birth by Caesarean Section and the Risk of Adult Psychosis: A Population-Based Cohort Study'. Schizophrenia bulletin, 42 :633-641 [DOI] [Details]
(2016)'The utility of cadaver-based approaches for the teaching of human anatomy: A survey of British and Irish anatomy teachers'
Balta JY;Cronin M;Cryan JF;O'Mahony SM; (2016) 'The utility of cadaver-based approaches for the teaching of human anatomy: A survey of British and Irish anatomy teachers'. Anatomical Sciences Education, [DOI] [Details]
(2016)'Lost in translation? The potential psychobiotic Lactobacillus rhamnosus (JB-1) fails to modulate stress or cognitive performance in healthy male subjects'
Kelly, John R.; Allen, Andrew P.; Temko, Andriy; Hutch, William; Kennedy, Paul J.; Farid, Niloufar; Murphy, Eileen; Boylan, Geraldine; Bienenstock, John; Cryan, John F.; Clarke, Gerard; Dinan, Timothy G. (2016) 'Lost in translation? The potential psychobiotic Lactobacillus rhamnosus (JB-1) fails to modulate stress or cognitive performance in healthy male subjects'. Brain Behav Immun,   [DOI] [Full Text] [Details]
(2016)'Obstetric mode of delivery and attention-deficit/hyperactivity disorder: a sibling-matched study'
Curran, EA;Khashan, AS;Dalman, C;Kenny, LC;Cryan, JF;Dinan, TG;Kearney, PM (2016) 'Obstetric mode of delivery and attention-deficit/hyperactivity disorder: a sibling-matched study'. International Journal of Epidemiology, 45 :532-542 [DOI] [Details]
(2016)'Distinct alterations in motor & reward seeking behavior are dependent on the gestational age of exposure to LPS-induced maternal immune activation'
Straley ME;Van Oeffelen W;Theze S;Sullivan AM;O'Mahony SM;Cryan JF;O'Keeffe GW; (2016) 'Distinct alterations in motor & reward seeking behavior are dependent on the gestational age of exposure to LPS-induced maternal immune activation'. Brain Behav Immun, [DOI] [Details]
(2016)'Pharmacotherapy for Neonatal Seizures: Current Knowledge and Future Perspectives'
Donovan, M. D.,Griffin, B. T.,Kharoshankaya, L.,Cryan, J. F.,Boylan, G. B. (2016) 'Pharmacotherapy for Neonatal Seizures: Current Knowledge and Future Perspectives'. Drugs, 76 (66):647-61   [Full Text] [Details]
(2016)'Inhibiting Neuroinflammation: The Role and Therapeutic Potential of GABA in Neuro-Immune Interactions'
Crowley T, Cryan JF, Downer EJ, O’Leary OF (2016) 'Inhibiting Neuroinflammation: The Role and Therapeutic Potential of GABA in Neuro-Immune Interactions'. Brain Behav Immun, 54 :260-277 [DOI] [Details]
(2016)'Regulation of prefrontal cortex myelination by the microbiota'
Hoban, AE,Stilling, RM,Ryan, FJ,Shanahan, F,Dinan, TG,Claesson, MJ,Clarke, G,Cryan, JF (2016) 'Regulation of prefrontal cortex myelination by the microbiota'. Translational Psychiatry, 6 [DOI] [Details]
(2016)'Cadaveric anatomy in the future of medical education: What is the surgeons view?'
Sheikh, AH,Barry, DS,Gutierrez, H,Cryan, JF,O'Keeffe, GW (2016) 'Cadaveric anatomy in the future of medical education: What is the surgeons view?'. Anatomical Sciences Education, 9 :203-208 [DOI] [Details]
(2016)'Behavioural and neurochemical consequences of chronic gut microbiota depletion during adulthood in the rat'
Hoban, A. E.,Moloney, R. D.,Golubeva, A. V.,McVey Neufeld, K. A.,O’Sullivan, O.,Patterson, E.,Stanton, C.,Dinan, T. G.,Clarke, G.,Cryan, J. F. (2016) 'Behavioural and neurochemical consequences of chronic gut microbiota depletion during adulthood in the rat'. Neuroscience, 339 :463-477   [DOI] [Full Text] [Details]
(2016)'The nuclear receptor Tlx regulates motor, cognitive and anxiety-related behaviours during adolescence and adulthood'
O’LearyJD, Kozareva DA, Hueston CM, O'Leary OF, Cryan JF and NolanYM (2016) 'The nuclear receptor Tlx regulates motor, cognitive and anxiety-related behaviours during adolescence and adulthood'. Behav. Brain Res, 306 :36-47 [DOI] [Details]
(2016)'Differential Roles of GABAB1 Subunit Isoforms on Locomotor Responses to Acute and Repeated Administration of Cocaine'
Jacobson LH, Sweeney F, Kaupmann K, O’Leary OF, Gassmann M, Bettler B, Cryan JF (2016) 'Differential Roles of GABAB1 Subunit Isoforms on Locomotor Responses to Acute and Repeated Administration of Cocaine'. Behavioral Brain Research, 298 (Pt B):12-16 [DOI] [Details]
(2016)'Distinct alterations in motor & reward seeking behavior are dependent on the gestational age of exposure to LPS-induced maternal immune activation'
Straley, M.E., Van Oeffelen, W., Theze, S., Sullivan, A.M.,O'Mahony, S.M., Cryan, J.F., O'Keeffe, G.W. (2016) 'Distinct alterations in motor & reward seeking behavior are dependent on the gestational age of exposure to LPS-induced maternal immune activation'. Brain Behav Immun,   [DOI] [Details]
(2016)'Metabotropic Glutamate Receptors in Central Nervous System Diseases'
Golubeva, AV;Moloney, RD;O'Connor, RM;Dinan, TG;Cryan, JF (2016) 'Metabotropic Glutamate Receptors in Central Nervous System Diseases'. Current drug targets, 17 :538-616 [DOI] [Details]
(2016)'Estrous cycle influences excitatory amino acid transport and visceral pain sensitivity in the rat: effects of early-life stress'
Moloney, RD,Sajjad, J,Foley, T,Felice, VD,Dinan, TG,Cryan, JF,O'Mahony, SM (2016) 'Estrous cycle influences excitatory amino acid transport and visceral pain sensitivity in the rat: effects of early-life stress'. Biology Of Sex Differences, 7 [DOI] [Details]
(2016)'Differential roles of GABA(B1) subunit isoforms on locomotor responses to acute and repeated administration of cocaine'
Jacobson, LH;Sweeney, FF;Kaupmann, K;O'Leary, OF;Gassmann, M;Bettler, B;Cryan, JF (2016) 'Differential roles of GABA(B1) subunit isoforms on locomotor responses to acute and repeated administration of cocaine'. Behavioural Brain Research, 298 :12-16 [DOI] [Details]
(2016)'The nuclear receptor Tlx regulates motor, cognitive and anxiety-related behaviours during adolescence and adulthood'
O'Leary JD;Kozareva DA;Hueston CM;O'Leary OF;Cryan JF;Nolan YM; (2016) 'The nuclear receptor Tlx regulates motor, cognitive and anxiety-related behaviours during adolescence and adulthood'. Behavioural Brain Research, 306 [DOI] [Details]
(2016)'Microbe-host interactions: Influence of the gut microbiota on the enteric nervous system'
Hyland NP;Cryan JF; (2016) 'Microbe-host interactions: Influence of the gut microbiota on the enteric nervous system'. Developmental Biology, [DOI] [Details]
(2015)'When ageing meets the blues: are current antidepressants effective in depressed aged patients'
Felice D, O’Leary OF, Cryan JF, Dinan TG, Gardier A, Sanchez C, David DJ (2015) 'When ageing meets the blues: are current antidepressants effective in depressed aged patients'. Neuroscience & Biobehavioral Reviews, 55 :478-497 [Details]
(2015)'Dietary trans-10, cis-12-conjugated linoleic acid alters fatty acid metabolism and microbiota composition in mice'
Marques, TM;Wall, R;O'Sullivan, O;Fitzgerald, GF;Shanahan, F;Quigley, EM;Cotter, PD;Cryan, JF;Dinan, TG;Ross, RP;Stanton, C (2015) 'Dietary trans-10, cis-12-conjugated linoleic acid alters fatty acid metabolism and microbiota composition in mice'. British Journal of Nutrition, 113 :728-738 [DOI] [Details]
(2015)'Imaging of oxygen gradients in giant umbrella cells: an ex vivo PLIM study'
Zhdanov AV, Golubeva AV, Okkelman IA, Cryan JF and Papkovsky DB (2015) 'Imaging of oxygen gradients in giant umbrella cells: an ex vivo PLIM study'. American Journal Of Physiology-Cell Physiology, 309 (7):C501-C509 [Details]
(2015)'RNAi therapeutics for brain cancer: current advancements in RNAi delivery strategies'
Malhotra M., Toulouse A., Godhino B.M.D.C., McCarthy D.J., Cryan J.F., O'Driscoll C.M. (2015) 'RNAi therapeutics for brain cancer: current advancements in RNAi delivery strategies'. Molecular Biosystems, 11 :2635-2657   [DOI] [Details]
(2015)'Treating Disorders of the Neonatal Central Nervous System: Pharmacokinetic and Pharmacodynamic Considerations with a Focus on Anti-epileptics-'
Donovan, M.D., Boylan, G.B., Murray, D.M., Cryan, J.F , Griffin, B.T., (2015) 'Treating Disorders of the Neonatal Central Nervous System: Pharmacokinetic and Pharmacodynamic Considerations with a Focus on Anti-epileptics-'. British Journal of Clinical Pharmacology,   [DOI] [Details]
(2015)'In vitro bidirectional permeability studies identify pharmacokinetic limitations of NKCC1 inhibitor bumetanide'
Donovan, M.D., Schellekens, H., Boylan, G.B., Cryan, J.F.,Griffin, B.T. (2015) 'In vitro bidirectional permeability studies identify pharmacokinetic limitations of NKCC1 inhibitor bumetanide'. European Journal of Pharmacology,   [DOI] [Details]
(2015)'Modulation of TLR3/TLR4 inflammatory signaling by the GABAB receptor agonist baclofen in glia and immune cells: relevance to therapeutic effects in multiple sclerosis'
Crowley T, Fitzpatrick J, Kuijper T, Cryan JF, O’Toole O, O'Leary OF, Downer EJ (2015) 'Modulation of TLR3/TLR4 inflammatory signaling by the GABAB receptor agonist baclofen in glia and immune cells: relevance to therapeutic effects in multiple sclerosis'. Frontiers in Cellular Neuroscience, 9 [Details]
(2015)'Cadaveric anatomy in the future of medical education: what is the surgeons view?'
Hassan-Sheik A, Barry DS, Cryan JF, O’Keeffe GW. (2015) 'Cadaveric anatomy in the future of medical education: what is the surgeons view?'. Anatomical Sciences Education, [DOI] [Details]
(2015)'Imaging of oxygen gradients in giant umbrella cells: an ex vivo PLIM study'
Zhdanov AV, Golubeva AV, Okkelman IA, Cryan JF, Papkovsky D (2015) 'Imaging of oxygen gradients in giant umbrella cells: an ex vivo PLIM study'. American Journal of Physiology - Cell Physiology, [DOI] [Details]
(2015)'Negative allosteric modulation of the mGlu7 receptor reduces visceral hypersensitivity in a stress-sensitive rat strain'
Moloney RD, Golubeva AV, O'Connor RM, Kalinichev M, Dinan TG, Cryan JF (2015) 'Negative allosteric modulation of the mGlu7 receptor reduces visceral hypersensitivity in a stress-sensitive rat strain'. Neurobiology of Stress, [DOI] [Details]
(2015)'Prenatal stress induces subtle alterations in major physiological sytems: a role for gut microbiota?'
Golubeva AV, Crampton S, Desbonnet L, Edge D, O’Sullivan O, Lomasney KW, Zhdanov AV, Crispie F, Moloney RD, Borre YE, Cotter PD, Hyland NP, O'Halloran KD,Dinan TG, O'Keeffe GW, Cryan JF (2015) 'Prenatal stress induces subtle alterations in major physiological sytems: a role for gut microbiota?'. Psychoneuroendocrinology, [Details]
(2015)'Prenatal Stress Induces Subtle Alterations in Major Physiological Systems: a Role for Gut Microbiota?'
Golubeva AV, Crampton S, Desbonnet L, Edge D, O’Sullivan O, Lomasney KW, Zhdanov AV, Moloney RD, Borre YE, Cotter PD, Hyland NP, O'Halloran KD, Dinan TG, O’Keeffe GW #, Cryan JF#. (2015) 'Prenatal Stress Induces Subtle Alterations in Major Physiological Systems: a Role for Gut Microbiota?'. Psychoneuroendocrinology, 60 :58-75 [Details]
(2015)'Metabotropic glutamate receptors in central nervous system diseases'
Golubeva AV, Moloney RD, O’Connor RM, Dinan TG, Cryan JF (2015) 'Metabotropic glutamate receptors in central nervous system diseases'. Current drug targets,   [Details]
(2015)'Acute tryptophan depletion reduces kynurenine levels: implications for treatment of impaired visuospatial memory performance in irritable bowel syndrome'
Kennedy, PJ;Allen, AP;O'Neill, A;Quigley, EMM;Cryan, JF;Dinan, TG;Clarke, G (2015) 'Acute tryptophan depletion reduces kynurenine levels: implications for treatment of impaired visuospatial memory performance in irritable bowel syndrome'. Journal of Psychopharmacology, 232 :1357-1371 [DOI] [Details]
(2015)'The impact of obstetric mode of delivery on childhood behavior'
O'Keeffe LM, Henriksen TB, Kenny LC, Cryan JF, Khashan AS, Khalaf SY, O'Neill SM (2015) 'The impact of obstetric mode of delivery on childhood behavior'. Social psychiatry and psychiatric epidemiology, [DOI] [Details]
(2015)'Prenatal stress-induced alterations in major physiological systems correlate with gut microbiota composition in adulthood'
Golubeva AV, Crampton S, Desbonnet L, Edge D, O’Sullivan O, Lomasney KW, Zhdanov AV, Crispie F, Moloney RD, Borre YE, Cotter PD, Hyland NP, O'Halloran KD,Dinan TG, O'Keeffe GW, Cryan JF (2015) 'Prenatal stress-induced alterations in major physiological systems correlate with gut microbiota composition in adulthood'. Psychoneuroendocrinology, 60 :58-74 [Details]
(2015)'Gut Microbiota and Brain Function: An Evolving Field in Neuroscience'
Foster, Jane A.; Lyte, Mark; Meyer, Emeran; Cryan, John F. (2015) 'Gut Microbiota and Brain Function: An Evolving Field in Neuroscience'. International Journal of Neuropsychopharmacology, 19 (5) [DOI] [Full Text] [Details]
(2015)'Negative allosteric modulation of the mGlu7 receptor reduces visceral hypersensitivity in a stress-sensitive rat strain'
Moloney, R. D. and Golubeva, A. V. and O'Connor, R. M. and Kalinichev, M. and Dinan, T. G. and Cryan, J. F. (2015) 'Negative allosteric modulation of the mGlu7 receptor reduces visceral hypersensitivity in a stress-sensitive rat strain'. Neurobiology of Stress, 2 :28-33   [DOI] [Details]
(2015)'Early-life stress-induced visceral hypersensitivity and anxiety behavior is reversed by histone deacetylase inhibition'
Moloney, R. D. and Stilling, R. M. and Dinan, T. G. and Cryan, J. F. (2015) 'Early-life stress-induced visceral hypersensitivity and anxiety behavior is reversed by histone deacetylase inhibition'. Neurogastroenterology and Motility, 27 (12):1831-1836   [DOI] [Details]
(2015)'Prenatal stress-induced alterations in major physiological systems correlate with gut microbiota composition in adulthood'
Golubeva, A. V. and Crampton, S. and Desbonnet, L. and Edge, D. and O'Sullivan, O. and Lomasney, K. W. and Zhdanov, A. V. and Crispie, F. and Moloney, R. D. and Borre, Y. E. and Cotter, P. D. and Hyland, N. P. and O'Halloran, K. D. and Dinan, T. G. and O'Keeffe, G. W. and Cryan, J. F. (2015) 'Prenatal stress-induced alterations in major physiological systems correlate with gut microbiota composition in adulthood'. Psychoneuroendocrinology, 60 :58-74   [DOI] [Details]
(2015)'Strain-dependent variations in visceral sensitivity: relationship to stress, anxiety and spinal glutamate transporter expression'
Moloney, R. D. and Dinan, T. G. and Cryan, J. F. (2015) 'Strain-dependent variations in visceral sensitivity: relationship to stress, anxiety and spinal glutamate transporter expression'. Genes Brain and Behavior, 14 (4):319-329   [DOI] [Details]
(2015)'Stress-induced visceral pain: toward animal models of irritable-bowel syndrome and associated comorbidities'
Moloney, R. D. and O'Mahony, S. M. and Dinan, T. G. and Cryan, J. F. (2015) 'Stress-induced visceral pain: toward animal models of irritable-bowel syndrome and associated comorbidities'. Frontiers in Psychiatry, 6   [DOI] [Details]
(2015)'Gut microbiota depletion from early adolescence in mice: Implications for brain and behaviour'
Desbonnet, L. and Clarke, G. and Traplin, A. and O'Sullivan, O. and Crispie, F. and Moloney, R. D. and Cotter, P. D. and Dinan, T. G. and Cryan, J. F. (2015) 'Gut microbiota depletion from early adolescence in mice: Implications for brain and behaviour'. Brain Behavior and Immunity, 48 :165-173   [DOI] [Details]
(2015)'Enhancing glutamatergic transmission during adolescence reverses early-life stress-induced deficits in the rewarding effects of cocaine in rats'
O'Connor, R. M. and Moloney, R. D. and Glennon, J. and Vlachou, S. and Cryan, J. F. (2015) 'Enhancing glutamatergic transmission during adolescence reverses early-life stress-induced deficits in the rewarding effects of cocaine in rats'. Neuropharmacology, 99 :168-176   [DOI] [Details]
(2015)'Imaging of oxygen gradients in giant umbrella cells: an ex vivo PLIM study'
Zhdanov, AV;Golubeva, AV;Okkelman, IA;Cryan, JF;Papkovsky, DB (2015) 'Imaging of oxygen gradients in giant umbrella cells: an ex vivo PLIM study'. American Journal of Physiology - Cell Physiology, 309 :501-509 [DOI] [Details]
(2015)'The effect of organic anion transporter 3 inhibitor probenecid on bumetanide levels in the brain: an integrated in vivo microdialysis study in the rat'
Donovan, MD;O'Brien, FE;Boylan, GB;Cryan, JF;Griffin, BT (2015) 'The effect of organic anion transporter 3 inhibitor probenecid on bumetanide levels in the brain: an integrated in vivo microdialysis study in the rat'. Journal of Pharmacy and Pharmacology, 67 :501-510 [DOI] [Details]
(2015)'SOS save our surgeons: Stress levels reduced by robotic surgery'
Hurley, AM;Kennedy, PJ;O'Connor, L;Dinan, TG;Cryan, JF;Boylan, G;O'Reilly, BA (2015) 'SOS save our surgeons: Stress levels reduced by robotic surgery'. Gynecological Surgery, 12 :197-206 [DOI] [Details]
(2015)'Early-life stress selectively affects gastrointestinal but not behavioral responses in a genetic model of brain-gut axis dysfunction'
Hyland, NP;O'Mahony, SM;O'Malley, D;O'Mahony, CM;Dinan, TG;Cryan, JF (2015) 'Early-life stress selectively affects gastrointestinal but not behavioral responses in a genetic model of brain-gut axis dysfunction'. Neurogastroenterology and Motility, 27 :105-113 [DOI] [Details]
(2015)'Strain-dependent variations in visceral sensitivity: relationship to stress, anxiety and spinal glutamate transporter expression'
Moloney, RD;Dinan, TG;Cryan, JF (2015) 'Strain-dependent variations in visceral sensitivity: relationship to stress, anxiety and spinal glutamate transporter expression'. Genes Brain And Behavior, 14 :319-329 [DOI] [Details]
(2015)'Microbes & neurodevelopment - Absence of microbiota during early life increases activity-related transcriptional pathways in the amygdala'
Stilling, RM;Ryan, FJ;Hoban, AE;Shanahan, F;Clarke, G;Claesson, MJ;Dinan, TG;Cryan, JF (2015) 'Microbes & neurodevelopment - Absence of microbiota during early life increases activity-related transcriptional pathways in the amygdala'. Brain Behav Immun, 50 :209-220 [DOI] [Details]
(2015)'N-3 Polyunsaturated Fatty Acids (PUFAs) Reverse the Impact of Early-Life Stress on the Gut Microbiota'
Pusceddu, MM;El Aidy, S;Crispie, F;O'Sullivan, O;Cotter, P;Stanton, C;Kelly, P;Cryan, JF;Dinan, TG (2015) 'N-3 Polyunsaturated Fatty Acids (PUFAs) Reverse the Impact of Early-Life Stress on the Gut Microbiota'. Plos One, 10 [DOI] [Details]
(2015)'SOS save our surgeons: Stress levels reduced by robotic surgery'
Hurley, A. M.; Kennedy, P.J.; O'Connor, L; Dinan, T.G.; Cryan, J.F.; Boylan, G.; O'Reilly, B.A. (2015) 'SOS save our surgeons: Stress levels reduced by robotic surgery'. Gynecological Surgery, [Details]
(2015)'Chronic P-glycoprotein inhibition increases the brain concentration of escitalopram: potential implications for treating depression'
O'Brien, FE;Moloney, GM;Scott, KA;O'Connor, RM;Clarke, G;Dinan, TG;Griffin, BT;Cryan, JF (2015) 'Chronic P-glycoprotein inhibition increases the brain concentration of escitalopram: potential implications for treating depression'. Pharmacology Research &Amp; Perspectives, 3 [DOI] [Details]
(2015)'Association Between Obstetric Mode of Delivery and Autism Spectrum Disorder A Population-Based Sibling Design Study'
Curran, EA;Dalman, C;Kearney, PM;Kenny, LC;Cryan, JF;Dinan, TG;Khashan, AS (2015) 'Association Between Obstetric Mode of Delivery and Autism Spectrum Disorder A Population-Based Sibling Design Study'. Jama Psychiatry, 72 :935-942 [DOI] [Details]
(2015)'The Master Puppeteer?: The impact of microbes on brain and behaviour'
Stilling R.;Dinan T.;Cryan J. (2015) 'The Master Puppeteer?: The impact of microbes on brain and behaviour'. Microbiology Today, 42 (1):26-29 [Details]
(2015)'Modulation of TLR3/TLR4 inflammatory signaling by the GABAB receptor agonist baclofen in glia and immune cells: relevance to therapeutic effects in multiple sclerosis'
Crowley, T;Fitzpatrick, JM;Kuijper, T;Cryan, JF;O'Toole, O;O'Leary, OF;Downer, EJ (2015) 'Modulation of TLR3/TLR4 inflammatory signaling by the GABAB receptor agonist baclofen in glia and immune cells: relevance to therapeutic effects in multiple sclerosis'. Frontiers in Cellular Neuroscience, 9 [DOI] [Details]
(2015)'Serum BDNF as a peripheral biomarker of treatment-resistant depression and the rapid antidepressant response: A comparison of ketamine and ECT'
Allen, AP;Naughton, M;Dowling, J;Walsh, A;Ismail, F;Shorten, G;Scott, L;McLoughlin, DM;Cryan, JF;Dinan, TG;Clarke, G (2015) 'Serum BDNF as a peripheral biomarker of treatment-resistant depression and the rapid antidepressant response: A comparison of ketamine and ECT'. Journal of Affective Disorders, 186 :306-311 [DOI] [Details]
(2015)'Modulation of TLR3/TLR4 inflammatory signaling by the GABAB receptor agonist baclofen in glia and immune cells: Relevance to therapeutic effects in multiple sclerosis'
Crowley T.;Fitzpatrick J.;Kuijper T.;Cryan J.;O’Toole O.;O’Leary O.;Downer E. (2015) 'Modulation of TLR3/TLR4 inflammatory signaling by the GABAB receptor agonist baclofen in glia and immune cells: Relevance to therapeutic effects in multiple sclerosis'. Frontiers in Cellular Neuroscience, 9 (JULY) [DOI] [Details]
(2015)'Human preservation techniques in anatomy: A 21st century medical education perspective'
Balta, J.Y., Cronin, M., Cryan, J. F. and O'Mahony, S. M. (2015) 'Human preservation techniques in anatomy: A 21st century medical education perspective'. Clinical Anatomy, 28 (6) [Details]
(2015)'Compared to casein, bovine lactoferrin reduces plasma leptin and corticosterone and affects hypothalamic gene expression without altering weight gain or fat mass in high fat diet fed C57/BL6J mice'
McManus, B;Korpela, R;O'Connor, P;Schellekens, H;Cryan, JF;Cotter, PD;Nilaweera, KN (2015) 'Compared to casein, bovine lactoferrin reduces plasma leptin and corticosterone and affects hypothalamic gene expression without altering weight gain or fat mass in high fat diet fed C57/BL6J mice'. Nutrition & Metabolism, 12 [DOI] [Details]
(2015)'Faster, better, stronger: Towards new antidepressant therapeutic strategies'
O'Leary, OF;Dinan, TG;Cryan, JF (2015) 'Faster, better, stronger: Towards new antidepressant therapeutic strategies'. European Journal of Pharmacology, 753 :32-50 [DOI] [Details]
(2015)'Prenatal stress-induced alterations in major physiological systems correlate with gut microbiota composition in adulthood'
Golubeva, AV;Crampton, S;Desbonnet, L;Edge, D;O'Sullivan, O;Lomasney, KW;Zhdanov, AV;Crispie, F;Moloney, RD;Borre, YE;Cotter, PD;Hyland, NP;O'Halloran, KD;Dinan, TG;O'Keeffe, GW;Cryan, JF (2015) 'Prenatal stress-induced alterations in major physiological systems correlate with gut microbiota composition in adulthood'. Psychoneuroendocrinology, 60 :58-74 [DOI] [Details]
(2015)'Gut microbiota depletion from early adolescence in mice: Implications for brain and behaviour'
Desbonnet, L,Clarke, G,Traplin, A,O'Sullivan, O,Crispie, F,Moloney, RD,Cotter, PD,Dinan, TG,Cryan, JF (2015) 'Gut microbiota depletion from early adolescence in mice: Implications for brain and behaviour'. Brain Behav Immun, 48 :165-173 [DOI] [Details]
(2015)'Downregulation of Umbilical Cord Blood Levels of miR-374a in Neonatal Hypoxic Ischemic Encephalopathy'
Looney, AM;Walsh, BH;Moloney, G;Grenham, S;Fagan, A;O'Keeffe, GW;Clarke, G;Cryan, JF;Dinan, TG;Boylan, GB;Murray, DM (2015) 'Downregulation of Umbilical Cord Blood Levels of miR-374a in Neonatal Hypoxic Ischemic Encephalopathy'. Journal of Pediatrics, 167 [DOI] [Details]
(2015)'Medical student perceptions of radiology use in anatomy teaching'
Murphy, KP;Crush, L;O'Malley, E;Daly, FE;Twomey, M;O'Tuathaigh, CMP;Maher, MM;Cryan, JF;O'Connor, OJ (2015) 'Medical student perceptions of radiology use in anatomy teaching'. Anatomical Sciences Education, 8 :510-517 [DOI] [Details]
(2015)'Ghrelin's Orexigenic Effect Is Modulated via a Serotonin 2C Receptor Interaction'
Schellekens, H;De Francesco, PN;Kandil, D;Theeuwes, WF;McCarthy, T;van Oeffelen, WEPA;Perello, M;Giblin, L;Dinan, TG;Cryan, JF (2015) 'Ghrelin's Orexigenic Effect Is Modulated via a Serotonin 2C Receptor Interaction'. ACS Chemical Neuroscience, 6 :1186-1197 [DOI] [Details]
(2015)'Synthesis and characterization of rabies virus glycoprotein-tagged amphiphilic cyclodextrins for siRNA delivery in human glioblastoma cells: In vitro analysis'
Gooding, M;Malhotra, M;McCarthy, DJ;Godinho, BMDC;Cryan, JF;Darcy, R;O'Driscoll, CM (2015) 'Synthesis and characterization of rabies virus glycoprotein-tagged amphiphilic cyclodextrins for siRNA delivery in human glioblastoma cells: In vitro analysis'. European Journal of Pharmaceutical Sciences, 71 :80-92 [DOI] [Details]
(2015)'Enhancing glutamatergic transmission during adolescence reverses early-life stress-induced deficits in the rewarding effects of cocaine in rats'
O'Connor, RM;Moloney, RD;Glennon, J;Vlachou, S;Cryan, JF (2015) 'Enhancing glutamatergic transmission during adolescence reverses early-life stress-induced deficits in the rewarding effects of cocaine in rats'. Neuropharmacology, 99 :168-176 [DOI] [Details]
(2015)'Cyclodextrin mediated delivery of NF-kappa B and SRF siRNA reduces the invasion potential of prostate cancer cells in vitro'
Evans, JC;McCarthy, J;Torres-Fuentes, C;Cryan, JF;Ogier, J;Darcy, R;Watson, RW;O'Driscoll, CM (2015) 'Cyclodextrin mediated delivery of NF-kappa B and SRF siRNA reduces the invasion potential of prostate cancer cells in vitro'. Gene Therapy, 22 :802-810 [DOI] [Details]
(2015)'Early-life stress-induced visceral hypersensitivity and anxiety behavior is reversed by histone deacetylase inhibition'
Moloney, RD,Stilling, RM,Dinan, TG,Cryan, JF (2015) 'Early-life stress-induced visceral hypersensitivity and anxiety behavior is reversed by histone deacetylase inhibition'. Neurogastroenterology and Motility, 27 :1831-1836 [DOI] [Details]
(2015)'Chronic P-glycoprotein inhibition increases the brain concentration of escitalopram: potential implications for treating depression'
O'Brien, F. E.,Moloney, G. M.,Scott, K. A.,O'Connor, R. M.,Clarke, G.,Dinan, T. G.,Griffin, B. T.,Cryan, J. F. (2015) 'Chronic P-glycoprotein inhibition increases the brain concentration of escitalopram: potential implications for treating depression'. Pharmacol Res Perspect, 3 (66)   [Details]
(2015)'Visceral Pain and Psychiatric Disorders'
Felice VD;Moloney RD;Cryan JF;Dinan TG;O'Mahony SM; (2015) 'Visceral Pain and Psychiatric Disorders'. Metabolic Effects Of Psychotropic Drugs, 30 [DOI] [Details]
(2015)'The impact of obstetric mode of delivery on childhood behavior'
Al Khalaf, SY,O'Neill, SM,O'Keeffe, LM,Henriksen, TB,Kenny, LC,Cryan, JF,Khashan, AS (2015) 'The impact of obstetric mode of delivery on childhood behavior'. Social Psychiatry And Psychiatric Epidemiology, 50 :1557-1567 [DOI] [Details]
(2015)'Bovine serum albumin as the dominant form of dietary protein reduces subcutaneous fat mass, plasma leptin and plasma corticosterone in high fat-fed C57/BL6J mice'
McManus, BL,Korpela, R,Speakman, JR,Cryan, JF,Cotter, PD,Nilaweera, KN (2015) 'Bovine serum albumin as the dominant form of dietary protein reduces subcutaneous fat mass, plasma leptin and plasma corticosterone in high fat-fed C57/BL6J mice'. British Journal of Nutrition, 114 :654-662 [DOI] [Details]
(2015)'Birth by Caesarean Section and the Risk of Adult Psychosis: A Population-Based Cohort Study'
O'Neill SM, Curran EA, Dalman C, Kenny LC, Kearney PM, Clarke G, Cryan JF, Dinan TG, Khashan AS. (2015) 'Birth by Caesarean Section and the Risk of Adult Psychosis: A Population-Based Cohort Study'. Schizophrenia Bulletinetin, [Details]
(2015)'A prospective study of C-reactive protein as a state marker in Cardiac Syndrome X'
Dollard, J;Kearney, P;Clarke, G;Moloney, G;Cryan, JF;Dinan, TG (2015) 'A prospective study of C-reactive protein as a state marker in Cardiac Syndrome X'. Brain Behav Immun, 43 :27-32 [DOI] [Details]
(2015)'The Omega-3 Polyunsaturated Fatty Acid Docosahexaenoic Acid (DHA) Reverses Corticosterone-Induced Changes in Cortical Neurons'
Pusceddu, Matteo M.; Nolan, Yvonne M.; Green, Holly F.; Robertson, Ruairi C.; Stanton, Catherine; Kelly, Philip; Cryan, John F.; Dinan, Timothy G. (2015) 'The Omega-3 Polyunsaturated Fatty Acid Docosahexaenoic Acid (DHA) Reverses Corticosterone-Induced Changes in Cortical Neurons'. International Journal of Neuropsychopharmacology, 9 (6) [DOI] [Full Text] [Details]
(2015)'Breaking down the barriers: the gut microbiome, intestinal permeability and stress-related psychiatric disorders'
Kelly JR;Kennedy PJ;Cryan JF;Dinan TG;Clarke G;Hyland NP; (2015) 'Breaking down the barriers: the gut microbiome, intestinal permeability and stress-related psychiatric disorders'. Frontiers in Cellular Neuroscience, 9 [DOI] [Details]
(2015)'Downregulation of Umbilical Cord Blood Levels of miR-374a in Neonatal Hypoxic Ischemic Encephalopathy'
Looney AM, Walsh BH, Moloney G, Grenham S, Fagan A, O'Keeffe GW, Clarke G, Cryan JF, Dinan TG, Boylan GB, Murray DM (2015) 'Downregulation of Umbilical Cord Blood Levels of miR-374a in Neonatal Hypoxic Ischemic Encephalopathy'. The Journal of Pediatrics, [DOI] [Details]
(2014)'Selective influence of host microbiota on cAMP-mediated ion transport in mouse colon'
Lomasney, KW;Houston, A;Shanahan, F;Dinan, TG;Cryan, JF;Hyland, NP (2014) 'Selective influence of host microbiota on cAMP-mediated ion transport in mouse colon'. Neuro-Gastroenterology and Motility, 26 :887-890 [DOI] [Details]
(2014)'Friends with social benefits: host-microbe interactions as a driver of brain evolution and development?'
Stilling, RM;Bordenstein, SR;Dinan, TG;Cryan, JF (2014) 'Friends with social benefits: host-microbe interactions as a driver of brain evolution and development?'. Frontiers in cellular and infection microbiology, 4 [DOI] [Details]
(2014)'The P-glycoprotein inhibitor cyclosporin A differentially influences behavioural and neurochemical responses to the antidepressant escitalopram'
O'Brien, FE;O'Connor, RM;Clarke, G;Donovan, MD;Dinan, TG;Griffin, BT;Cryan, JF (2014) 'The P-glycoprotein inhibitor cyclosporin A differentially influences behavioural and neurochemical responses to the antidepressant escitalopram'. Behavioural Brain Research, 261 :17-25 [DOI] [Details]
(2014)'GABA(B(1)) receptor subunit isoforms differentially regulate stress resilience'
O'Leary, OF;Felice, D;Galimberti, S;Savignac, HM;Bravo, JA;Crowley, T;Yacoubi, M;Vaugeois, JM;Gassmann, M;Bettler, B;Dinan, TG;Cryan, JF (2014) 'GABA(B(1)) receptor subunit isoforms differentially regulate stress resilience'. Proceedings of The National Academy of Sciences of The United States of America, 111 :15232-15237 [DOI] [Details]
(2014)'Long-lasting glutamatergic modulation induced by neonatal GABA enhancement in mice'
Melamed, O;Levav-Rabkin, T;Zukerman, C;Clarke, G;Cryan, JF;Dinan, TG;Grossman, Y;Golan, HM (2014) 'Long-lasting glutamatergic modulation induced by neonatal GABA enhancement in mice'. Neuropharmacology, 79 :616-625 [DOI] [Details]
(2014)'Protein Quality and the Protein to Carbohydrate Ratio within a High Fat Diet Influences Energy Balance and the Gut Microbiota In C57BL/6J Mice'
McAllan, L;Skuse, P;Cotter, PD;O' Connor, P;Cryan, JF;Ross, RP;Fitzgerald, G;Roche, HM;Nilaweera, KN (2014) 'Protein Quality and the Protein to Carbohydrate Ratio within a High Fat Diet Influences Energy Balance and the Gut Microbiota In C57BL/6J Mice'. Plos One, 9 [DOI] [Details]
(2014)'Toll-Like Receptor 4 Regulates Chronic Stress-Induced Visceral Pain in Mice'
Tramullas, M;Finger, BC;Moloney, RD;Golubeva, AV;Moloney, G;Dinan, TG;Cryan, JF (2014) 'Toll-Like Receptor 4 Regulates Chronic Stress-Induced Visceral Pain in Mice'. Biological Psychiatry, 76 :340-348 [DOI] [Details]
(2014)'Toll-like receptor 4 regulates chronic stress-induced visceral pain in mice'
Tramullas M, Finger BC, Moloney RD, Golubeva AV, Dinan TG, Cryan JF (2014) 'Toll-like receptor 4 regulates chronic stress-induced visceral pain in mice'. Biological Psychiatry, [DOI] [Details]
(2014)'The Impact of Microbiota on Brain and Behavior: Mechanisms & Therapeutic Potential'
Borre, YE,Moloney, RD,Clarke, G,Dinan, TG,Cryan, JF,Lyte, M,Cryan, JF (2014) 'The Impact of Microbiota on Brain and Behavior: Mechanisms & Therapeutic Potential'. Genomic Imprinting, 817 :373-403 [DOI] [Details]
(2014)'Gut Microbes and the Brain: Paradigm Shift in Neuroscience'
Mayer, EA,Knight, R,Mazmanian, SK,Cryan, JF,Tillisch, K (2014) 'Gut Microbes and the Brain: Paradigm Shift in Neuroscience'. The Journal of neuroscience : the official journal of the Society for Neuroscience, 34 :15490-15496 [DOI] [Details]
(2014)'Toll-Like Receptor 4 Regulates Chronic Stress-Induced Visceral Pain in Mice'
Tramullas, M. and Finger, B. C. and Moloney, R. D. and Golubeva, A. V. and Moloney, G. and Dinan, T. G. and Cryan, J. F. (2014) 'Toll-Like Receptor 4 Regulates Chronic Stress-Induced Visceral Pain in Mice'. Biological Psychiatry, 76 (4):340-348   [DOI] [Details]
(2014)'The microbiome: stress, health and disease'
Moloney, R. D. and Desbonnet, L. and Clarke, G. and Dinan, T. G. and Cryan, J. F. (2014) 'The microbiome: stress, health and disease'. Mammalian Genome, 25 (1-2):49-74   [DOI] [Details]
(2014)'Medical student knowledge regarding radiology before and after a radiological anatomy module: implications for vertical integration and self-directed learning'
Murphy K.;Crush L.;O’Malley E.;Daly F.;O’Tuathaigh C.;O’Connor O.;Cryan J.;Maher M. (2014) 'Medical student knowledge regarding radiology before and after a radiological anatomy module: implications for vertical integration and self-directed learning'. Macromolecular Research, 5 (5):629-634 [DOI] [Details]
(2014)'Microbial genes, brain & behaviour - epigenetic regulation of the gut-brain axis'
Stilling R.;Dinan T.;Cryan J. (2014) 'Microbial genes, brain & behaviour - epigenetic regulation of the gut-brain axis'. Genes Brain And Behavior, 13 (1):69-86 [DOI] [Details]
(2014)'Negative Allosteric Modulation of the mGlu7 Receptor Reduces Visceral Ypersensitivity in a Sress-Sensitive Rat Strain'
Moloney, R. D. and O'Connor, R. M. and Kalinichev, M. and Dinan, T. G. and Cryan, J. F. (2014) 'Negative Allosteric Modulation of the mGlu7 Receptor Reduces Visceral Ypersensitivity in a Sress-Sensitive Rat Strain'. Current Neuropharmacology, 12 :42-43   [Details]
(2014)'Effect of acute swim stress on plasma corticosterone and brain monoamine levels in bidirectionally selected DxH recombinant inbred mouse strains differing in fear recall and extinction'
Browne, CA;Hanke, J;Rose, C;Walsh, I;Foley, T;Clarke, G;Schwegler, H;Cryan, JF;Yilmazer-Hanke, D (2014) 'Effect of acute swim stress on plasma corticosterone and brain monoamine levels in bidirectionally selected DxH recombinant inbred mouse strains differing in fear recall and extinction'. Stress-The International Journal On The Biology Of Stress, 17 :471-483 [DOI] [Details]
(2014)'PEGylated cyclodextrins as novel siRNA nanosystems: correlations between polyethylene glycol length and nanoparticle stability'
Godinho BM;Ogier JR;Quinlan A;Darcy R;Griffin BT;Cryan JF;O'Driscoll CM; (2014) 'PEGylated cyclodextrins as novel siRNA nanosystems: correlations between polyethylene glycol length and nanoparticle stability'. International Journal of Pharmaceutics, 473 (1-2) [DOI] [Details]
(2014)'Activation but not blockade of GABA(B) receptors during early-life alters anxiety in adulthood in BALB/c mice'
Sweeney, FE;O'Leary, OF;Cryan, JF (2014) 'Activation but not blockade of GABA(B) receptors during early-life alters anxiety in adulthood in BALB/c mice'. Neuropharmacology, 81 :303-310 [DOI] [Details]
(2013)'P-glycoprotein Inhibition Increases the Brain Distribution and Antidepressant-Like Activity of Escitalopram in Rodents'
O'Brien, FE;O'Connor, RM;Clarke, G;Dinan, TG;Griffin, BT;Cryan, JF (2013) 'P-glycoprotein Inhibition Increases the Brain Distribution and Antidepressant-Like Activity of Escitalopram in Rodents'. Neuropsychopharmacology, 38 :2209-2219 [DOI] [Details]
(2013)'Cationic and PEGylated Amphiphilic Cyclodextrins: Co-Formulation Opportunities for Neuronal Sirna Delivery'
O'Mahony, AM;Ogier, J;Darcy, R;Cryan, JF;O'Driscoll, CM (2013) 'Cationic and PEGylated Amphiphilic Cyclodextrins: Co-Formulation Opportunities for Neuronal Sirna Delivery'. Plos One, 8 [DOI] [Details]
(2013)'Differential visceral nociceptive, behavioural and neurochemical responses to an immune challenge in the stress-sensitive Wistar Kyoto rat strain'
Mahony, SMO;Clarke, G;McKernan, DP;Bravo, JA;Dinan, TG;Cryan, JF (2013) 'Differential visceral nociceptive, behavioural and neurochemical responses to an immune challenge in the stress-sensitive Wistar Kyoto rat strain'. Behavioural Brain Research, 253 :310-317 [DOI] [Details]
(2013)'The orthosteric GABA(A) receptor ligand Thio-4-PIOL displays distinctly different functional properties at synaptic and extrasynaptic receptors'
Hoestgaard-Jensen, K;O'Connor, RM;Dalby, NO;Simonsen, C;Finger, BC;Golubeva, A;Hammer, H;Bergmann, ML;Kristiansen, U;Krogsgaard-Larsen, P;Brauner-Osborne, H;Ebert, B;Frolund, B;Cryan, JF;Jensen, AA (2013) 'The orthosteric GABA(A) receptor ligand Thio-4-PIOL displays distinctly different functional properties at synaptic and extrasynaptic receptors'. British Journal of Pharmacology, 170 :919-932 [DOI] [Details]
(2013)'The effects of mGlu(7) receptor modulation in behavioural models sensitive to antidepressant action in two mouse strains'
O'Connor, RM;Cryan, JF (2013) 'The effects of mGlu(7) receptor modulation in behavioural models sensitive to antidepressant action in two mouse strains'. Behavioural Pharmacology, 24 :105-113 [DOI] [Details]
(2013)'Ghrelin At the Interface of Obesity and Reward'
Schellekens H.;Dinan T.;Cryan J. (2013) 'Ghrelin At the Interface of Obesity and Reward'. Vitamins and hormones, 91 :285-323 [DOI] [Details]
(2013)'microRNAs as novel antidepressant targets: converging effects of ketamine and electroconvulsive shock therapy in the rat hippocampus'
O'Connor, RM;Grenham, S;Dinan, TG;Cryan, JF (2013) 'microRNAs as novel antidepressant targets: converging effects of ketamine and electroconvulsive shock therapy in the rat hippocampus'. International Journal of Neuropsychopharmacology, 16 :1885-1892 [DOI] [Details]
(2013)'Whey protein isolate counteracts the effects of a high-fat diet on energy intake and hypothalamic and adipose tissue expression of energy balance-related genes'
McAllan, L;Keane, D;Schellekens, H;Roche, HM;Korpela, R;Cryan, JF;Nilaweera, KN (2013) 'Whey protein isolate counteracts the effects of a high-fat diet on energy intake and hypothalamic and adipose tissue expression of energy balance-related genes'. British Journal of Nutrition, 110 :2114-2126 [DOI] [Details]
(2013)'The orthosteric GABAA receptor ligand Thio‐4‐PIOL displays distinctly different functional properties at synaptic and extrasynaptic receptors'
Hoestgaard‐Jensen K, O'Connor RM, Dalby NO, Simonsen Ch, Finger BC, Golubeva AV, Hammer H, Bergmann ML, Kristiansen U, Krogsgaard‐Larsen P, Bräuner‐Osborne H, Ebert B, Frølund B, Cryan JF, Jensen AA (2013) 'The orthosteric GABAA receptor ligand Thio‐4‐PIOL displays distinctly different functional properties at synaptic and extrasynaptic receptors'. British Journal of Pharmacology, [DOI] [Details]
(2013)'The microbiome-gut-brain axis during early life regulates the hippocampal serotonergic system in a sex-dependent manner'
Clarke, G. and Grenham, S. and Scully, P. and Fitzgerald, P. and Moloney, R. D. and Shanahan, F. and Dinan, T. G. and Cryan, J. F. (2013) 'The microbiome-gut-brain axis during early life regulates the hippocampal serotonergic system in a sex-dependent manner'. Molecular Psychiatry, 18 (6):666-673   [DOI] [Details]
(2013)'Adult siRNA-induced knockdown of mGlu(7) receptors reduces anxiety in the mouse'
O'Connor, RM;Thakker, DR;Schmutz, M;van der Putten, H;Hoyer, D;Flor, PJ;Cryan, JF (2013) 'Adult siRNA-induced knockdown of mGlu(7) receptors reduces anxiety in the mouse'. Neuropharmacology, 72 :66-73 [DOI] [Details]
(2013)'LITHIUM AUGMENTATION OF THE EFFECTS OF DESIPRAMINE IN A MOUSE MODEL OF TREATMENT-RESISTANT DEPRESSION: A ROLE FOR HIPPOCAMPAL CELL PROLIFERATION'
O'Leary, OF;Zandy, S;Dinan, TG;Cryan, JF (2013) 'LITHIUM AUGMENTATION OF THE EFFECTS OF DESIPRAMINE IN A MOUSE MODEL OF TREATMENT-RESISTANT DEPRESSION: A ROLE FOR HIPPOCAMPAL CELL PROLIFERATION'. Neuroscience, 228 :36-46 [DOI] [Details]
(2012)'Genetic Strain Differences in Learned Fear Inhibition Associated with Variation in Neuroendocrine, Autonomic, and Amygdala Dendritic Phenotypes'
Camp, MC;MacPherson, KP;Lederle, L;Graybeal, C;Gaburro, S;DeBrouse, LM;Ihne, JL;Bravo, JA;O'Connor, RM;Ciocchi, S;Wellman, CL;Luthi, A;Cryan, JF;Singewald, N;Holmes, A (2012) 'Genetic Strain Differences in Learned Fear Inhibition Associated with Variation in Neuroendocrine, Autonomic, and Amygdala Dendritic Phenotypes'. Neuropsychopharmacology, 37 :1534-1547 [DOI] [Details]
(2012)'Dynamic 5-HT2C Receptor Editing in a Mouse Model of Obesity'
Schellekens, H;Clarke, G;Jeffery, IB;Dinan, TG;Cryan, JF (2012) 'Dynamic 5-HT2C Receptor Editing in a Mouse Model of Obesity'. Plos One, 7 [DOI] [Details]
(2012)'Inhibition of P-glycoprotein enhances transport of imipramine across the blood-brain barrier: microdialysis studies in conscious freely moving rats'
O'Brien, FE;Clarke, G;Fitzgerald, P;Dinan, TG;Griffin, BT;Cryan, JF (2012) 'Inhibition of P-glycoprotein enhances transport of imipramine across the blood-brain barrier: microdialysis studies in conscious freely moving rats'. British Journal of Pharmacology, 166 :1333-1343 [DOI] [Details]
(2012)'The temporal impact of chronic intermittent psychosocial stress on high-fat diet-induced alterations in body weight'
Finger, BC;Dinan, TG;Cryan, JF (2012) 'The temporal impact of chronic intermittent psychosocial stress on high-fat diet-induced alterations in body weight'. Psychoneuroendocrinology, 37 :729-741 [DOI] [Details]
(2012)'A click chemistry route to 2-functionalised PEGylated and cationic beta-cyclodextrins: co-formulation opportunities for siRNA delivery'
O'Mahony, AM;Ogier, J;Desgranges, S;Cryan, JF;Darcy, R;O'Driscoll, CM (2012) 'A click chemistry route to 2-functionalised PEGylated and cationic beta-cyclodextrins: co-formulation opportunities for siRNA delivery'. Organic & Biomolecular Chemistry, 10 :4954-4960 [DOI] [Details]
(2012)'Diet-induced obesity blunts the behavioural effects of ghrelin: studies in a mouse-progressive ratio task'
Finger, BC;Dinan, TG;Cryan, JF (2012) 'Diet-induced obesity blunts the behavioural effects of ghrelin: studies in a mouse-progressive ratio task'. Journal of Psychopharmacology, 220 :173-181 [DOI] [Details]
(2012)'DIFFERENTIAL LIPOPOLYSACCHARIDE-INDUCED IMMUNE ALTERATIONS IN THE HIPPOCAMPUS OF TWO MOUSE STRAINS: EFFECTS OF STRESS'
Browne, CA;O'Brien, FE;Connor, TJ;Dinan, TG;Cryan, JF (2012) 'DIFFERENTIAL LIPOPOLYSACCHARIDE-INDUCED IMMUNE ALTERATIONS IN THE HIPPOCAMPUS OF TWO MOUSE STRAINS: EFFECTS OF STRESS'. Neuroscience, 225 :237-248 [DOI] [Details]
(2012)'Early-life stress induces visceral hypersensitivity in mice'
Moloney, R. D. and O'Leary, O. F. and Felice, D. and Bettler, B. and Dinan, T. G. and Cryan, J. F. (2012) 'Early-life stress induces visceral hypersensitivity in mice'. Neuroscience Letters, 512 (2):99-102   [DOI] [Details]
(2012)'Phenotypic effects of repeated psychosocial stress during adolescence in mice mutant for the schizophrenia risk gene neuregulin-1: A putative model of gene x environment interaction'
Desbonnet, L;O'Tuathaigh, C;Clarke, G;O'Leary, C;Petit, E;Clarke, N;Tighe, O;Lai, D;Harvey, R;Cryan, JF;Dinan, TG;Waddington, JL (2012) 'Phenotypic effects of repeated psychosocial stress during adolescence in mice mutant for the schizophrenia risk gene neuregulin-1: A putative model of gene x environment interaction'. Brain Behav Immun, 26 :660-671 [DOI] [Details]
(2012)'Early-life stress induces visceral hypersensitivity in mice'
Moloney, RD;O'Leary, OF;Felice, D;Bettler, B;Dinan, TG;Cryan, JF (2012) 'Early-life stress induces visceral hypersensitivity in mice'. Neuroscience Letters, 512 :99-102 [DOI] [Details]
(2012)'An effective dietary method for chronic tryptophan depletion in two mouse strains illuminates a role for 5-HT in nesting behaviour'
Browne, CA;Clarke, G;Dinan, TG;Cryan, JF (2012) 'An effective dietary method for chronic tryptophan depletion in two mouse strains illuminates a role for 5-HT in nesting behaviour'. Neuropharmacology, 62 :1903-1915 [DOI] [Details]
(2012)'Communication between gastrointestinal bacteria and the nervous system'
Bravo, JA;Julio-Pieper, M;Forsythe, P;Kunze, W;Dinan, TG;Bienenstock, J;Cryan, JF (2012) 'Communication between gastrointestinal bacteria and the nervous system'. Current Opinion In Pharmacology, 12 :667-672 [DOI] [Details]
(2012)'Using the rat forced swim test to assess antidepressant-like activity in rodents'
Slattery, DA;Cryan, JF (2012) 'Using the rat forced swim test to assess antidepressant-like activity in rodents'. Nature Protocols, 7 :1009-1014 [DOI] [Details]
(2012)'A distinct profile of tryptophan metabolism along the kynurenine pathway downstream of toll-like receptor activation in irritable bowel syndrome'
Clarke, G;McKernan, DP;Gaszner, G;Quigley, EM;Cryan, JF;Dinan, TG (2012) 'A distinct profile of tryptophan metabolism along the kynurenine pathway downstream of toll-like receptor activation in irritable bowel syndrome'. Frontiers In Pharmacology, 3 [DOI] [Details]
(2012)'Gender-dependent consequences of chronic olanzapine in the rat: effects on body weight, inflammatory, metabolic and microbiota parameters'
Davey, KJ,O'Mahony, SM,Schellekens, H,O'Sullivan, O,Bienenstock, J,Cotter, PD,Dinan, TG,Cryan, JF (2012) 'Gender-dependent consequences of chronic olanzapine in the rat: effects on body weight, inflammatory, metabolic and microbiota parameters'. Psychopharmacology, 221 :155-169 [DOI] [Details]
(2011)'The effects of gabapentin in two animal models of co-morbid anxiety and visceral hypersensitivity'
O'Mahony, SM;Coelho, AM;Fitzgerald, P;Lee, K;Winchester, W;Dinan, TG;Cryan, JF (2011) 'The effects of gabapentin in two animal models of co-morbid anxiety and visceral hypersensitivity'. European Journal of Pharmacology, 667 :169-174 [DOI] [Details]
(2011)'Neonatal maternal separation in the rat impacts on the stress responsivity of central corticotropin-releasing factor receptors in adulthood'
O'Malley, D;Dinan, TG;Cryan, JF (2011) 'Neonatal maternal separation in the rat impacts on the stress responsivity of central corticotropin-releasing factor receptors in adulthood'. Journal of Psychopharmacology, 214 :221-229 [DOI] [Details]
(2011)'HIGH-FAT DIET SELECTIVELY PROTECTS AGAINST THE EFFECTS OF CHRONIC SOCIAL STRESS IN THE MOUSE'
Finger, BC;Dinan, TG;Cryan, JF (2011) 'HIGH-FAT DIET SELECTIVELY PROTECTS AGAINST THE EFFECTS OF CHRONIC SOCIAL STRESS IN THE MOUSE'. Neuroscience, 192 :351-360 [DOI] [Details]
(2011)'Altered peripheral toll-like receptor responses in the irritable bowel syndrome'
McKernan, DP;Gaszner, G;Quigley, EM;Cryan, JF;Dinan, TG (2011) 'Altered peripheral toll-like receptor responses in the irritable bowel syndrome'. Alimentary Pharmacology And Therapeutics, 33 :1045-1052 [DOI] [Details]
(2011)'Differential stress-induced alterations in tryptophan hydroxylase activity and serotonin turnover in two inbred mouse strains'
Browne, CA;Clarke, G;Dinan, TG;Cryan, JF (2011) 'Differential stress-induced alterations in tryptophan hydroxylase activity and serotonin turnover in two inbred mouse strains'. Neuropharmacology, 60 :683-691 [DOI] [Details]
(2011)'Strain differences in the neurochemical response to chronic restraint stress in the rat: Relevance to depression'
O'Mahony, CM;Clarke, G;Gibney, S;Dinan, TG;Cryan, JF (2011) 'Strain differences in the neurochemical response to chronic restraint stress in the rat: Relevance to depression'. Pharmacology Biochemistry and Behavior, 97 :690-699 [DOI] [Details]
(2011)'Colonic soluble mediators from the maternal separation model of irritable bowel syndrome activate submucosal neurons via an interleukin-6-dependent mechanism'
O'Malley, D;Liston, M;Hyland, NP;Dinan, TG;Cryan, JF (2011) 'Colonic soluble mediators from the maternal separation model of irritable bowel syndrome activate submucosal neurons via an interleukin-6-dependent mechanism'. American Journal of Physiology - Gastrointestinal and Liver Physiology, 300 :241-252 [DOI] [Details]
(2010)'The Behavioral Genetics of Serotonin: Relevance to Anxiety and Depression'
O'Leary O.;Cryan J. (2010) 'The Behavioral Genetics of Serotonin: Relevance to Anxiety and Depression'. Handbook Of Anxiety And Fear, 21 (C):749-789 [DOI] [Details]
(2010)'GABA B receptors and depression. Current status'
Cryan J.;Slattery D. (2010) 'GABA B receptors and depression. Current status'. Advances In Pharmacology, 58 (C):427-451 [DOI] [Details]
(2010)'Distinct alterations in colonic morphology and physiology in two rat models of enhanced stress-induced anxiety and depression-like behaviour'
O'Malley, D;Julio-Pieper, M;Gibney, SM;Dinan, TG;Cryan, JF (2010) 'Distinct alterations in colonic morphology and physiology in two rat models of enhanced stress-induced anxiety and depression-like behaviour'. Stress-The International Journal On The Biology Of Stress, 13 :114-122 [DOI] [Details]
(2010)'A novel role for the metabotropic glutamate receptor-7: modulation of faecal water content and colonic electrolyte transport in the mouse'
Julio-Pieper, M;Hyland, NP;Bravo, JA;Dinan, TG;Cryan, JF (2010) 'A novel role for the metabotropic glutamate receptor-7: modulation of faecal water content and colonic electrolyte transport in the mouse'. British Journal of Pharmacology, 160 :367-375 [DOI] [Details]
(2010)'EFFECTS OF THE PROBIOTIC BIFIDOBACTERIUM INFANTIS IN THE MATERNAL SEPARATION MODEL OF DEPRESSION'
Desbonnet, L;Garrett, L;Clarke, G;Kiely, B;Cryan, JF;Dinan, TG (2010) 'EFFECTS OF THE PROBIOTIC BIFIDOBACTERIUM INFANTIS IN THE MATERNAL SEPARATION MODEL OF DEPRESSION'. Neuroscience, 170 :1179-1188 [DOI] [Details]
(2010)'Leptin-deficient mice retain normal appetitive spatial learning yet exhibit marked increases in anxiety-related behaviours'
Finger, BC;Dinan, TG;Cryan, JF (2010) 'Leptin-deficient mice retain normal appetitive spatial learning yet exhibit marked increases in anxiety-related behaviours'. Journal of Psychopharmacology, 210 :559-568 [DOI] [Details]
(2010)'IBs: an epigenetic perspective'
Dinan, TG;Cryan, J;Shanahan, F;Keeling, PWN;Quigley, EMM (2010) 'IBs: an epigenetic perspective'. Nature reviews. Gastroenterology & hepatology, 7 :465-471 [DOI] [Details]
(2010)'The Behavioral Genetics of Serotonin: Relevance to Anxiety and Depression'
O'Leary, OF,Cryan, JF,Muller, CP,Jacobs, BL (2010) 'The Behavioral Genetics of Serotonin: Relevance to Anxiety and Depression'. Handbook Of Anxiety And Fear, 21 :749-789 [DOI] [Details]
(2010)'Riluzole Normalizes Early-Life Stress-Induced Visceral Hypersensitivity in Rats: Role of Spinal Glutamate Reuptake Mechanisms'
Gosselin, RD;O'Connor, RM;Tramullas, M;Julio-Pieper, M;Dinan, TG;Cryan, JF (2010) 'Riluzole Normalizes Early-Life Stress-Induced Visceral Hypersensitivity in Rats: Role of Spinal Glutamate Reuptake Mechanisms'. Gastroenterology, 138 :2418-2425 [DOI] [Details]
(2010)'The probiotic Bifidobacterium infantis 35624 displays visceral antinociceptive effects in the rat'
McKernan, DP;Fitzgerald, P;Dinan, TG;Cryan, JF (2010) 'The probiotic Bifidobacterium infantis 35624 displays visceral antinociceptive effects in the rat'. Neurogastroenterology and Motility, 22 [DOI] [Details]
(2009)'P.2.03 Restraint stress alters tryptophan hydroxylase 2 activity in BALB/c mice: relevance to depression'
Browne C.;Clarke G.;Dinan T.;Cryan J. (2009) 'P.2.03 Restraint stress alters tryptophan hydroxylase 2 activity in BALB/c mice: relevance to depression'. European Neuropsychopharmacology, 19 :S35-S36 [DOI] [Details]
(2008)'The rostral anterior cingulate cortex modulates the efficiency of amygdala-dependent fear learning'
Bissiere, S;Plachta, N;Hoyer, D;McAllister, KH;Olpe, HR;Grace, AA;Cryan, JF (2008) 'The rostral anterior cingulate cortex modulates the efficiency of amygdala-dependent fear learning'. Biological Psychiatry, 63 :821-831 [DOI] [Details]
(2008)'The glutamatergic system as a potential therapeutic target for the treatment of anxiety disorders'
Cryan, JF,Dev, KK,Blanchard, RJ,Blanchard, DC,Griebel, G,Nutt, D (2008) 'The glutamatergic system as a potential therapeutic target for the treatment of anxiety disorders'. Handbook Of Anxiety And Fear, 17 :269-301 [DOI] [Details]
(2008)'mGluR7 facilitates extinction of aversive memories and controls amygdala plasticity'
Fendt, M;Schmid, S;Thakker, DR;Jacobson, LH;Yamamoto, R;Mitsukawa, K;Maier, R;Natt, F;Husken, D;Kelly, PH;McAllister, KH;Hoyer, D;van der Putten, H;Cryan, JF;Flor, PJ (2008) 'mGluR7 facilitates extinction of aversive memories and controls amygdala plasticity'. Molecular Psychiatry, 13 :970-979 [DOI] [Details]
(2008)'Evaluation of the anxiolytic-like profile of the GABA(B) receptor positive modulator CGP7930 in rodents'
Jacobson, LH;Cryan, JF (2008) 'Evaluation of the anxiolytic-like profile of the GABA(B) receptor positive modulator CGP7930 in rodents'. Neuropharmacology, 54 :854-862 [DOI] [Details]
(2007)'Animal models of mood disorders: recent developments'
Cryan, JF;Slattery, DA (2007) 'Animal models of mood disorders: recent developments'. Current Opinion In Psychiatry, 20 :1-7 [Details]
(2007)'GABAB receptor-positive modulation decreases selective molecular and behavioral effects of cocaine'
Lhuillier L.;Mombereau C.;Cryan J.;Kaupmann K. (2007) 'GABAB receptor-positive modulation decreases selective molecular and behavioral effects of cocaine'. Neuropsychopharmacology, 32 (2):388-398 [DOI] [Details]
(2007)'Evaluation of reward processes in an animal model of depression'
Slattery, DA;Markou, A;Cryan, JF (2007) 'Evaluation of reward processes in an animal model of depression'. Journal of Psychopharmacology, 190 :555-568 [DOI] [Details]
(2007)'Behavioral evaluation of mice deficient in GABA(B(1)) receptor isoforms in tests of unconditioned anxiety'
Jacobson, LH;Bettler, B;Kaupmann, K;Cryan, JF (2007) 'Behavioral evaluation of mice deficient in GABA(B(1)) receptor isoforms in tests of unconditioned anxiety'. Journal of Psychopharmacology, 190 :541-553 [DOI] [Details]
(2007)'Specific roles of GABA(B(l)) receptor isoforms in cognition'
Jacobson, LH;Kelly, PH;Bettler, B;Kaupmann, K;Cryan, JF (2007) 'Specific roles of GABA(B(l)) receptor isoforms in cognition'. Behavioural Brain Research, 181 :158-162 [DOI] [Details]
(2007)'GABA(B) receptor-positive modulation-induced blockade of the rewarding properties of nicotine is associated with a reduction in nucleus accumbens Delta FosB accumulation'
Mombereau, C;Lhuillier, L;Kaupmann, K;Cryan, JF (2007) 'GABA(B) receptor-positive modulation-induced blockade of the rewarding properties of nicotine is associated with a reduction in nucleus accumbens Delta FosB accumulation'. Journal of Pharmacology and Experimental Therapeutics, 321 :172-177 [DOI] [Details]
(2007)'Amyloid precursor protein knockdown by siRNA impairs spontaneous alternation in adult mice'
Senechal, Y;Kelly, PH;Cryan, JF;Natt, F;Dev, KK (2007) 'Amyloid precursor protein knockdown by siRNA impairs spontaneous alternation in adult mice'. Journal of Neurochemistry, 102 :1928-1940 [DOI] [Details]
(2006)'The rostral anterior cingulate cortex modulates depression but not anxiety-related behaviour in the rat'
Bissiere, S;McAllister, KH;Olpe, HR;Cryan, JF (2006) 'The rostral anterior cingulate cortex modulates depression but not anxiety-related behaviour in the rat'. Behavioural Brain Research, 175 :195-199 [DOI] [Details]
(2006)'GABA(B(1)) receptor subunit isoforms exert a differential influence on baseline but not GABA(B) receptor agonist-induced changes in mice'
Jacobson, LH;Bettler, B;Kaupmann, K;Cryan, JF (2006) 'GABA(B(1)) receptor subunit isoforms exert a differential influence on baseline but not GABA(B) receptor agonist-induced changes in mice'. Journal of Pharmacology and Experimental Therapeutics, 319 :1317-1326 [DOI] [Details]
(2006)'GABA(B(1)) receptor isoforms differentially mediate the acquisition and extinction of aversive taste memories'
Jacobson, LH;Kelly, PH;Bettler, B;Kaupmann, K;Cryan, JF (2006) 'GABA(B(1)) receptor isoforms differentially mediate the acquisition and extinction of aversive taste memories'. Neuroscience, 26 :8800-8803 [DOI] [Details]
(2006)'Concomitant deficits in working memory and fear extinction are functionally dissociated from reduced anxiety in metabotropic glutamate receptor 7-deficient mice'
Callaerts-Vegh Z.;Beckers T.;Ball S.;Baeyens F.;Callaerts P.;Cryan J.;Molnar E.;D'Hooge R. (2006) 'Concomitant deficits in working memory and fear extinction are functionally dissociated from reduced anxiety in metabotropic glutamate receptor 7-deficient mice'. Neuroscience, 26 (24):6573-6582 [DOI] [Details]
(2005)'A selective metabotropic glutamate receptor 7 agonist: Activation of receptor signaling via an allosteric site modulates stress parameters in vivo'
Mitsukawa K.;Yamamoto R.;Ofner S.;Nozulak J.;Pescott O.;Lukic S.;Stoehr N.;Mombereau C.;Kuhn R.;McAllister K.;Van Der Putten H.;Cryan J.;Flor P. (2005) 'A selective metabotropic glutamate receptor 7 agonist: Activation of receptor signaling via an allosteric site modulates stress parameters in vivo'. Proceedings of The National Academy of Sciences of The United States of America, 102 (51):18712-18717 [DOI] [Details]
(2015)'Synthesis and characterization of rabies virus glycoprotein-tagged amphiphilic cyclodextrins for siRNA delivery in human glioblastoma cells: in-vitro analysis'
Gooding M*, Malhotra M*, McCarthy DJ, Godinho BMDC, Cryan JF, Darcy R, O’Driscoll CM (2015) 'Synthesis and characterization of rabies virus glycoprotein-tagged amphiphilic cyclodextrins for siRNA delivery in human glioblastoma cells: in-vitro analysis'. European Journal of Pharmaceutical Science, [Details]
(2015)'Gut Microbiota: The Conductor in the Orchestra of Immune-Neuroendocrine Communication'
Aidy SE, Dinan TG, Cryan JF (2015) 'Gut Microbiota: The Conductor in the Orchestra of Immune-Neuroendocrine Communication'. Clinical Therapeutics, [DOI] [Details]
(2015)'Down regulation of microRNA-374a in Neonatal Hypoxic Ischemic Encepahlopathy'
Looney AM, Walsh BH, Moloney G, Grenham S, Fagan A, O’Keeffe GW, Clarke G, Cryan JF, Dinan TG, Boylan GB, Murray DM. (2015) 'Down regulation of microRNA-374a in Neonatal Hypoxic Ischemic Encepahlopathy'. Journal of Paediatrics, [Details]
(2015)'Gut microbiota depletion from early adolescence in mice: Implications for brain and behaviour'
Desbonnet L, Clarke G, Traplin A, O'Sullivan O, Crispie F, Moloney RD, Cotter PD, Dinan TG, Cryan JF (2015) 'Gut microbiota depletion from early adolescence in mice: Implications for brain and behaviour'. Brain Behav Immun, [DOI] [Details]
(2015)'Early-life stress selectively affects gastrointestinal but not behavioral responses in a genetic model of brain-gut axis dysfunction'
Hyland NP, O'Mahony SM, O'Malley D, O'Mahony CM, Dinan TG, Cryan JF (2015) 'Early-life stress selectively affects gastrointestinal but not behavioral responses in a genetic model of brain-gut axis dysfunction'. Neurogastroenterol & Motility, 27 (1):105-113 [DOI] [Details]
(2015)'Ghrelin's Orexigenic Effect Is Modulated via a Serotonin 2C Receptor Interaction'
Schellekens H, De Francesco PN, Kandil D, Theeuwes WF, McCarthy T, van Oeffelen WE, Perelló M, Giblin L, Dinan TG, Cryan JF (2015) 'Ghrelin's Orexigenic Effect Is Modulated via a Serotonin 2C Receptor Interaction'. ACS chemical neuroscience, [DOI] [Details]
(2015)'Serotonin, tryptophan metabolism and the brain-gut-microbiome axis'
O'Mahony SM, Clarke G, Borre YE, Dinan TG, Cryan JF (2015) 'Serotonin, tryptophan metabolism and the brain-gut-microbiome axis'. Behavioral Brain Research, 277 :32-48 [DOI] [Details]
(2015)'Dietary trans-10, cis-12-conjugated linoleic acid alters fatty acid metabolism and microbiota composition in mice'
O'Sullivan O, Fitzgerald GF, Shanahan F, Quigley EM, Cotter PD, Cryan JF, Dinan TG, Ross RP, Stanton C, Marques TM, Wall R (2015) 'Dietary trans-10, cis-12-conjugated linoleic acid alters fatty acid metabolism and microbiota composition in mice'. The British journal of nutrition, 113 (5):728-738 [DOI] [Details]
(2015)'GABAB receptors as a therapeutic strategy in substance use disorders: focus on positive allosteric modulators'
Filip M, Frankowska M, Sadakierska-Chudy A, Suder A, Szumiec L, Mierzejewski P, Bienkowski P, Przegalinski E, Cryan JF (2015) 'GABAB receptors as a therapeutic strategy in substance use disorders: focus on positive allosteric modulators'. Neuropharmacology, 88 :36-47 [DOI] [Details]
(2015)'Bifidobacteria modulate cognitive processes in an anxious mouse strain'
Savignac HM, Tramullas M, Kiely B, Dinan TG, Cryan JF (2015) 'Bifidobacteria modulate cognitive processes in an anxious mouse strain'. Behavioral Brain Research, 287 :59-72 [DOI] [Details]
(2015)'More than a gut feeling: the microbiota regulates neurodevelopment and behavior'
Cryan JF, Dinan TG (2015) 'More than a gut feeling: the microbiota regulates neurodevelopment and behavior'. Neuropsychopharmacology, 40 (1):241-242 [DOI] [Details]
(2015)'Nanoparticles and the blood-brain barrier: advancing from in-vitro models towards therapeutic significance'
Mc Carthy DJ, Malhotra M, O'Mahony AM, Cryan JF, O'Driscoll CM (2015) 'Nanoparticles and the blood-brain barrier: advancing from in-vitro models towards therapeutic significance'. Pharmaceutical research, 32 (4):1161-1185 [DOI] [Details]
(2015)'Delivering a disease-modifying treatment for Huntington's disease'
Godinho BM, Malhotra M, O'Driscoll CM, Cryan JF (2015) 'Delivering a disease-modifying treatment for Huntington's disease'. Drug discovery today, 20 (1):50-64 [DOI] [Details]
(2015)'n-3 PUFAs have beneficial effects on anxiety and cognition in female rats: Effects of early life stress'
Pusceddu MM, Kelly P, Ariffin N, Cryan JF, Clarke G, Dinan TG (2015) 'n-3 PUFAs have beneficial effects on anxiety and cognition in female rats: Effects of early life stress'. Psychoneuroendocrinology, 58 :79-90 [DOI] [Details]
(2015)'Microbiota regulation of the Mammalian gut-brain axis'
Burokas A, Moloney RD, Dinan TG, Cryan JF (2015) 'Microbiota regulation of the Mammalian gut-brain axis'. Advances In Applied Microbiology, Vol 76, 91 :1-62 [DOI] [Details]
(2015)'Metabotropic Glutamate Receptors in Central Nervous System Diseases'
Golubeva AV, Moloney RD, O'Connor RM, Dinan TG, Cryan JF (2015) 'Metabotropic Glutamate Receptors in Central Nervous System Diseases'. Current drug targets, [Details]
(2015)'Adult Hippocampal Neurogenesis Is Regulated by the Microbiome'
Ogbonnaya ES, Clarke G, Shanahan F, Dinan TG, Cryan JF, O'Leary OF (2015) 'Adult Hippocampal Neurogenesis Is Regulated by the Microbiome'. Biological psychiatry, [DOI] [Details]
(2015)'Whey protein isolate decreases murine stomach weight and intestinal length and alters the expression of Wnt signalling-associated genes'
McAllan L, Speakman JR, Cryan JF, Nilaweera KN (2015) 'Whey protein isolate decreases murine stomach weight and intestinal length and alters the expression of Wnt signalling-associated genes'. The British journal of nutrition, :1-8 [DOI] [Details]
(2015)'Thinking small: towards microRNA-based therapeutics for anxiety disorders'
Scott KA, Hoban AE, Clarke G, Moloney GM, Dinan TG, Cryan JF (2015) 'Thinking small: towards microRNA-based therapeutics for anxiety disorders'. Expert opinion on investigational drugs, 24 (4):529-542 [DOI] [Details]
(2015)'Acute tryptophan depletion reduces kynurenine levels: implications for treatment of impaired visuospatial memory performance in irritable bowel syndrome'
Kennedy PJ, Allen AP, O'Neill A, Quigley EM, Cryan JF, Dinan TG, Clarke G (2015) 'Acute tryptophan depletion reduces kynurenine levels: implications for treatment of impaired visuospatial memory performance in irritable bowel syndrome'. Psychopharmacology, 232 (8):1357-1371 [DOI] [Details]
(2015)'Collective unconscious: How gut microbes shape human behavior'
Dinan TG, Stilling RM, Stanton C, Cryan JF (2015) 'Collective unconscious: How gut microbes shape human behavior'. Journal of Psychiatric Research, 63 :1-9 [DOI] [Details]
(2015)'Stress-induced visceral pain: toward animal models of irritable-bowel syndrome and associated comorbidities'
Moloney RD, O'Mahony SM, Dinan TG, Cryan JF (2015) 'Stress-induced visceral pain: toward animal models of irritable-bowel syndrome and associated comorbidities'. Frontiers in psychiatry, 6 [DOI] [Details]
(2015)'Synthesis and characterization of rabies virus glycoprotein-tagged amphiphilic cyclodextrins for siRNA delivery in human glioblastoma cells: in vitro analysis'
Gooding M, Malhotra M, McCarthy DJ, Godinho BM, Cryan JF, Darcy R, O'Driscoll CM (2015) 'Synthesis and characterization of rabies virus glycoprotein-tagged amphiphilic cyclodextrins for siRNA delivery in human glioblastoma cells: in vitro analysis'. European Journal of Pharmaceutical Sciences, 71 :80-92 [DOI] [Details]
(2015)'Streptozotocin-induced type-1-diabetes disease onset in Sprague-Dawley rats is associated with an altered intestinal microbiota composition and decreased diversity'
Patterson E, Marques TM, O'Sullivan O, Fitzgerald P, Fitzgerald GF, Cotter PD, Dinan TG, Cryan JF, Stanton C, Ross RP (2015) 'Streptozotocin-induced type-1-diabetes disease onset in Sprague-Dawley rats is associated with an altered intestinal microbiota composition and decreased diversity'. Microbiology, 161 (Pt 1):182-193 [DOI] [Details]
(2015)'A prospective study of C-reactive protein as a state marker in Cardiac Syndrome X'
Dollard J, Kearney P, Clarke G, Moloney G, Cryan JF, Dinan TG (2015) 'A prospective study of C-reactive protein as a state marker in Cardiac Syndrome X'. Brain Behav Immun, 43 :27-32 [DOI] [Details]
(2015)'Research Review: Birth by caesarean section and development of autism spectrum disorder and attention-deficit/hyperactivity disorder: a systematic review and meta-analysis'
Curran EA, O'Neill SM, Cryan JF, Kenny LC, Dinan TG, Khashan AS, Kearney PM (2015) 'Research Review: Birth by caesarean section and development of autism spectrum disorder and attention-deficit/hyperactivity disorder: a systematic review and meta-analysis'. Journal of child psychology and psychiatry, and allied disciplines, 56 (5):500-508 [DOI] [Details]
(2015)'Early-life stress selectively affects gastrointestinal but not behavioral responses in a genetic model of brain-gut axis dysfunction'
Hyland NP, O'Mahony SM, O'Malley D, O'Mahony CM, Dinan TG, Cryan JF (2015) 'Early-life stress selectively affects gastrointestinal but not behavioral responses in a genetic model of brain-gut axis dysfunction'. Neurogastroenterology and Motility, 27 (1):105-113 [Details]
(2014)'Nanoparticles and the blood-brain barrier: from in-vitro models to therapeutic significance'
McCarthy DJ*, Malhotra M*, O’Mahony A, Cryan JF, O’Driscoll CM. (2014) 'Nanoparticles and the blood-brain barrier: from in-vitro models to therapeutic significance'. Pharmaceutical Research, :1-25   [DOI] [Details]
(2014)'Bifidobacteria exert strain-specific effects on stress-related behavior and physiology in BALB/c mice'
Savignac HM, Kiely B, Dinan TG, Cryan JF (2014) 'Bifidobacteria exert strain-specific effects on stress-related behavior and physiology in BALB/c mice'. Neurogastroenterol & Motility, 26 (11):1615-1627 [DOI] [Details]
(2014)'Friends with social benefits: host-microbe interactions as a driver of brain evolution and development?'
Stilling RM, Bordenstein SR, Dinan TG, Cryan JF (2014) 'Friends with social benefits: host-microbe interactions as a driver of brain evolution and development?'. Frontiers in cellular and infection microbiology, 4 [DOI] [Details]
(2014)'Research Review: Birth by caesarean section and development of autism spectrum disorder and attention-deficit/hyperactivity disorder: a systematic review and meta-analysis'
Curran EA, O'Neill SM, Cryan JF, Kenny LC, Dinan TG, Khashan AS, Kearney PM. (2014) 'Research Review: Birth by caesarean section and development of autism spectrum disorder and attention-deficit/hyperactivity disorder: a systematic review and meta-analysis'. Journal of Child Psychology & Psychiatry, [Details]
(2014)'Irritable bowel syndrome: A microbiome-gut-brain axis disorder?'
Kennedy, P. J., Cryan, J. F., Dinan, T. G., Clarke, G (2014) 'Irritable bowel syndrome: A microbiome-gut-brain axis disorder?'. World Journal of Gastroenterology, :14105-14125 [DOI] [Details]
(2014)'A sustained hypothalamic-pituitary-adrenal axis response to acute psychosocial stress in irritable bowel syndrome'
Kennedy, P. J., Cryan, J. F., Quigley, E. M., Dinan, T. G., & Clarke, G (2014) 'A sustained hypothalamic-pituitary-adrenal axis response to acute psychosocial stress in irritable bowel syndrome'. Psychological medicine, 44 (14):3123-34 [DOI] [Details]
(2014)'Acute tryptophan depletion reduces kynurenine levels: implications for treatment of impaired visuospatial memory performance in irritable bowel syndrome'
Kennedy, P. J., Allen, A. P., O'Neill, A., Quigley, E. M., Cryan, J. F., Dinan, T. G. & Clarke, G. (2014) 'Acute tryptophan depletion reduces kynurenine levels: implications for treatment of impaired visuospatial memory performance in irritable bowel syndrome'. Psychopharmacology (Berl)Psychopharmacology (Berl), (Epub ahead of print]) [DOI] [Details]
(2014)'Medical student knowledge regarding radiology before and after a radiological anatomy module: implications for vertical integration and self-directed learning'
Murphy KP, Crush L, O'Malley E, Daly FE, O'Tuathaigh CM, O'Connor OJ, Cryan JF, Maher MM (2014) 'Medical student knowledge regarding radiology before and after a radiological anatomy module: implications for vertical integration and self-directed learning'. Insights into imaging, 5 (5):629-634 [DOI] [Full Text] [Details]
(2014)'Toll-like receptor 4 regulates chronic stress-induced visceral pain in mice'
Tramullas M, Finger BC, Moloney RD, Golubeva AV, Moloney G, Dinan TG, Cryan JF (2014) 'Toll-like receptor 4 regulates chronic stress-induced visceral pain in mice'. Biological psychiatry, 76 (4):340-348 [DOI] [Details]
(2014)'Priming for health: gut microbiota acquired in early life regulates physiology, brain and behaviour'
Clarke G, O'Mahony SM, Dinan TG, Cryan JF (2014) 'Priming for health: gut microbiota acquired in early life regulates physiology, brain and behaviour'. Acta paediatrica (Oslo, Norway : 1992), 103 (8):812-819 [DOI] [Details]
(2014)'Differential activation of the prefrontal cortex and amygdala following psychological stress and colorectal distension in the maternally separated rat'
Felice VD, Gibney SM, Gosselin RD, Dinan TG, O'Mahony SM, Cryan JF (2014) 'Differential activation of the prefrontal cortex and amygdala following psychological stress and colorectal distension in the maternally separated rat'. Neuroscience, 267 :252-262 [DOI] [Details]
(2014)'The microbiome: stress, health and disease'
Moloney RD, Desbonnet L, Clarke G, Dinan TG, Cryan JF (2014) 'The microbiome: stress, health and disease'. Mammalian Genome, 25 (1-2):49-74 [DOI] [Details]
(2014)'Drugs, genes and the blues: pharmacogenetics of the antidepressant response from mouse to man'
O'Leary OF, O'Brien FE, O'Connor RM, Cryan JF (2014) 'Drugs, genes and the blues: pharmacogenetics of the antidepressant response from mouse to man'. Pharmacology, biochemistry, and behavior, 123 :55-76 [DOI] [Details]
(2014)'Irritable bowel syndrome: a microbiome-gut-brain axis disorder?'
Kennedy PJ, Cryan JF, Dinan TG, Clarke G (2014) 'Irritable bowel syndrome: a microbiome-gut-brain axis disorder?'. World journal of gastroenterology : WJG, 20 (39):14105-14125 [DOI] [Details]
(2014)'GABAB(1) receptor subunit isoforms differentially regulate stress resilience'
O'Leary OF, Felice D, Galimberti S, Savignac HM, Bravo JA, Crowley T, El Yacoubi M, Vaugeois JM, Gassmann M, Bettler B, Dinan TG, Cryan JF (2014) 'GABAB(1) receptor subunit isoforms differentially regulate stress resilience'. Proceedings of The National Academy of Sciences of The United States of America, 111 (42):15232-15237 [DOI] [Details]
(2014)'Genomics of schizophrenia: time to consider the gut microbiome?'
Dinan TG, Borre YE, Cryan JF (2014) 'Genomics of schizophrenia: time to consider the gut microbiome?'. Molecular psychiatry, 19 (12):1252-1257 [DOI] [Details]
(2014)'The impact of microbiota on brain and behavior: mechanisms & therapeutic potential'
Borre YE, Moloney RD, Clarke G, Dinan TG, Cryan JF (2014) 'The impact of microbiota on brain and behavior: mechanisms & therapeutic potential'. Genomic Imprinting, 817 :373-403 [DOI] [Details]
(2014)'PEGylated cyclodextrins as novel siRNA nanosystems: correlations between polyethylene glycol length and nanoparticle stability'
Godinho BM, Ogier JR, Quinlan A, Darcy R, Griffin BT, Cryan JF, O'Driscoll CM (2014) 'PEGylated cyclodextrins as novel siRNA nanosystems: correlations between polyethylene glycol length and nanoparticle stability'. International journal of pharmaceutics, 473 (1-2):105-112 [DOI] [Details]
(2014)'Minireview: Gut microbiota: the neglected endocrine organ'
Clarke G, Stilling RM, Kennedy PJ, Stanton C, Cryan JF, Dinan TG (2014) 'Minireview: Gut microbiota: the neglected endocrine organ'. Molecular endocrinology (Baltimore, Md.), 28 (8):1221-1238 [DOI] [Details]
(2014)'The mouse cyclophosphamide model of bladder pain syndrome: tissue characterization, immune profiling, and relationship to metabotropic glutamate receptors'
Golubeva AV, Zhdanov AV, Mallel G, Dinan TG, Cryan JF (2014) 'The mouse cyclophosphamide model of bladder pain syndrome: tissue characterization, immune profiling, and relationship to metabotropic glutamate receptors'. Physiological reports, 2 (3) [DOI] [Details]
(2014)'Selective influence of host microbiota on cAMP-mediated ion transport in mouse colon'
Lomasney KW, Houston A, Shanahan F, Dinan TG, Cryan JF, Hyland NP (2014) 'Selective influence of host microbiota on cAMP-mediated ion transport in mouse colon'. Neurogastroenterol & Motility, 26 (6):887-890 [DOI] [Details]
(2014)'Biological and psychological markers of stress in humans: focus on the Trier Social Stress Test'
Allen AP, Kennedy PJ, Cryan JF, Dinan TG, Clarke G (2014) 'Biological and psychological markers of stress in humans: focus on the Trier Social Stress Test'. Neuroscience and biobehavioral reviews, 38 :94-124 [DOI] [Details]
(2014)'Differential nanotoxicological and neuroinflammatory liabilities of non-viral vectors for RNA interference in the central nervous system'
Godinho BM, McCarthy DJ, Torres-Fuentes C, Beltrán CJ, McCarthy J, Quinlan A, Ogier JR, Darcy R, O'Driscoll CM, Cryan JF (2014) 'Differential nanotoxicological and neuroinflammatory liabilities of non-viral vectors for RNA interference in the central nervous system'. Biomaterials, 35 (1):489-499 [DOI] [Details]
(2014)'Cognitive performance in irritable bowel syndrome: evidence of a stress-related impairment in visuospatial memory'
Kennedy PJ, Clarke G, O'Neill A, Groeger JA, Quigley EM, Shanahan F, Cryan JF, Dinan TG (2014) 'Cognitive performance in irritable bowel syndrome: evidence of a stress-related impairment in visuospatial memory'. Psychological medicine, 44 (7):1553-1566 [DOI] [Details]
(2014)'Microbiota and neurodevelopmental windows: implications for brain disorders'
Borre YE, O'Keeffe GW, Clarke G, Stanton C, Dinan TG, Cryan JF (2014) 'Microbiota and neurodevelopmental windows: implications for brain disorders'. Trends In Molecular Medicine, 20 (9):509-518 [DOI] [Details]
(2014)'Converging effects of a Bifidobacterium and Lactobacillus probiotic strain on mouse intestinal physiology'
Lomasney KW, Cryan JF, Hyland NP (2014) 'Converging effects of a Bifidobacterium and Lactobacillus probiotic strain on mouse intestinal physiology'. American Journal of Physiology - Gastrointestinal and Liver Physiology, 307 (2):1-7 [DOI] [Details]
(2014)'Effect of acute swim stress on plasma corticosterone and brain monoamine levels in bidirectionally selected DxH recombinant inbred mouse strains differing in fear recall and extinction'
Browne CA, Hanke J, Rose C, Walsh I, Foley T, Clarke G, Schwegler H, Cryan JF, Yilmazer-Hanke D (2014) 'Effect of acute swim stress on plasma corticosterone and brain monoamine levels in bidirectionally selected DxH recombinant inbred mouse strains differing in fear recall and extinction'. Stress (Amsterdam, Netherlands), 17 (6):471-483 [DOI] [Details]
(2014)'Early-life stress induces persistent alterations in 5-HT1A receptor and serotonin transporter mRNA expression in the adult rat brain'
Bravo JA, Dinan TG, Cryan JF (2014) 'Early-life stress induces persistent alterations in 5-HT1A receptor and serotonin transporter mRNA expression in the adult rat brain'. Frontiers in molecular neuroscience, 7 [DOI] [Details]
(2014)'Immune modulation of the brain-gut-microbe axis'
El Aidy S, Dinan TG, Cryan JF (2014) 'Immune modulation of the brain-gut-microbe axis'. Frontiers In Microbiology, 5 [DOI] [Details]
(2014)'Protein quality and the protein to carbohydrate ratio within a high fat diet influences energy balance and the gut microbiota in C57BL/6J mice'
McAllan L, Skuse P, Cotter PD, O'Connor P, Cryan JF, Ross RP, Fitzgerald G, Roche HM, Nilaweera KN (2014) 'Protein quality and the protein to carbohydrate ratio within a high fat diet influences energy balance and the gut microbiota in C57BL/6J mice'. Plos One, 9 (2) [DOI] [Details]
(2014)'A review of ketamine in affective disorders: current evidence of clinical efficacy, limitations of use and pre-clinical evidence on proposed mechanisms of action'
Naughton M, Clarke G, O'Leary OF, Cryan JF, Dinan TG (2014) 'A review of ketamine in affective disorders: current evidence of clinical efficacy, limitations of use and pre-clinical evidence on proposed mechanisms of action'. Journal of affective disorders, 156 :24-35 [DOI] [Details]
(2014)'Differential visceral pain sensitivity and colonic morphology in four common laboratory rat strains'
O'Malley D, Julio-Pieper M, O'Mahony SM, Dinan TG, Cryan JF (2014) 'Differential visceral pain sensitivity and colonic morphology in four common laboratory rat strains'. Experimental physiology, 99 (2):359-367 [DOI] [Details]
(2014)'A ventral view on antidepressant action: roles for adult hippocampal neurogenesis along the dorsoventral axis'
O'Leary OF, Cryan JF (2014) 'A ventral view on antidepressant action: roles for adult hippocampal neurogenesis along the dorsoventral axis'. Trends in pharmacological sciences, 35 (12):675-687 [DOI] [Details]
(2014)'Gut microbes and the brain: paradigm shift in neuroscience'
Mayer EA, Knight R, Mazmanian SK, Cryan JF, Tillisch K (2014) 'Gut microbes and the brain: paradigm shift in neuroscience'. The Journal of neuroscience : the official journal of the Society for Neuroscience, 34 (46):15490-15496 [DOI] [Details]
(2014)'Strain differences in stress-induced changes in central CRF1 receptor expression'
O'Malley D, Julio-Piepera M, Dinan TG, Cryan JF (2014) 'Strain differences in stress-induced changes in central CRF1 receptor expression'. Neuroscience letters, 561 :192-197 [DOI] [Details]
(2014)'The P-glycoprotein inhibitor cyclosporin A differentially influences behavioural and neurochemical responses to the antidepressant escitalopram'
O'Brien FE, O'Connor RM, Clarke G, Donovan MD, Dinan TG, Griffin BT, Cryan JF (2014) 'The P-glycoprotein inhibitor cyclosporin A differentially influences behavioural and neurochemical responses to the antidepressant escitalopram'. Behavioral Brain Research, 261 :17-25 [DOI] [Details]
(2014)'Activation but not blockade of GABAB receptors during early-life alters anxiety in adulthood in BALB/c mice'
Sweeney FF, O'Leary OF, Cryan JF (2014) 'Activation but not blockade of GABAB receptors during early-life alters anxiety in adulthood in BALB/c mice'. Neuropharmacology, 81 :303-310 [DOI] [Details]
(2014)'Medical student perceptions of radiology use in anatomy teaching'
Murphy KP, Crush L, O'Malley E,Daly FE, Twomey M, O'Tuathaigh CM , Maher MM, Cryan JF, O'Connor OJ (2014) 'Medical student perceptions of radiology use in anatomy teaching'. Anatomical Sciences Education, [DOI] [Details]
(2014)'P. 1.009 A combined in vitro, in vivo and in silico approach to develop and optimise a novel antiepileptic strategy in neonatal seizures'
Donovan, M and O'Brien, FE and Boylan, GB and Griffin, BT and Cryan, JF (2014) 'P. 1.009 A combined in vitro, in vivo and in silico approach to develop and optimise a novel antiepileptic strategy in neonatal seizures'. European Neuropsychopharmacology, 24 (Supplement 1) [Details]
(2014)'Adolescent brain vulnerability and psychopathology through the generations: role of diet and dopamine'
O'Connor RM, Cryan JF (2014) 'Adolescent brain vulnerability and psychopathology through the generations: role of diet and dopamine'. Biological psychiatry, 75 (1):4-6 [DOI] [Details]
(2014)'Microbiota is essential for social development in the mouse'
Desbonnet L, Clarke G, Shanahan F, Dinan TG, Cryan JF (2014) 'Microbiota is essential for social development in the mouse'. Molecular psychiatry, 19 (2):146-148 [DOI] [Details]
(2014)'Delivering a disease-modifying treatment for Huntington’s disease'
Godinho BMDC, Malhotra M, O’Driscoll C and Cryan J. (2014) 'Delivering a disease-modifying treatment for Huntington’s disease'. Drug Discovery Today, 20 (1):50-64   [Details]
(2013)'microRNAs as novel antidepressant targets: converging effects of ketamine and electroconvulsive shock therapy in the rat hippocampus'
O'Connor RM, Grenham S, Dinan TG, Cryan JF (2013) 'microRNAs as novel antidepressant targets: converging effects of ketamine and electroconvulsive shock therapy in the rat hippocampus'. 16 (8):1885-1892 [DOI] [Details]
(2013)'Self-assembling modified ß-cyclodextrin nanoparticles as neuronal siRNA delivery vectors: focus on Huntington's disease'
Godinho BM, Ogier JR, Darcy R, O'Driscoll CM, Cryan JF (2013) 'Self-assembling modified ß-cyclodextrin nanoparticles as neuronal siRNA delivery vectors: focus on Huntington's disease'. Molecular pharmaceutics, 10 (2):640-649 [DOI] [Details]
(2013)'Impact of early-life stress, on group III mGlu receptor levels in the rat hippocampus: effects of ketamine, electroconvulsive shock therapy and fluoxetine treatment'
O' Connor RM, Pusceddu MM, Dinan TG, Cryan JF (2013) 'Impact of early-life stress, on group III mGlu receptor levels in the rat hippocampus: effects of ketamine, electroconvulsive shock therapy and fluoxetine treatment'. Neuropharmacology, 66 :236-241 [DOI] [Details]
(2013)'Adult siRNA-induced knockdown of mGlu7 receptors reduces anxiety in the mouse'
O'Connor RM, Thakker DR, Schmutz M, van der Putten H, Hoyer D, Flor PJ, Cryan JF (2013) 'Adult siRNA-induced knockdown of mGlu7 receptors reduces anxiety in the mouse'. Neuropharmacology, 72 :66-73 [DOI] [Details]
(2013)'Towards translational rodent models of depression'
O'Leary OF, Cryan JF (2013) 'Towards translational rodent models of depression'. Cell Tissue Research, 354 (1):141-153 [DOI] [Details]
(2013)'Hippocampal group III mGlu receptor mRNA levels are not altered in specific mouse models of stress, depression and antidepressant action'
O'Connor RM, Pusceddu MM, O'Leary OF, Savignac HM, Bravo JA, El Yacoubi M, Vaugeois JM, Dinan TG, Cryan JF (2013) 'Hippocampal group III mGlu receptor mRNA levels are not altered in specific mouse models of stress, depression and antidepressant action'. Pharmacology, biochemistry, and behavior, 103 (3):561-567 [DOI] [Details]
(2013)'Melancholic microbes: a link between gut microbiota and depression?'
Dinan TG, Cryan JF (2013) 'Melancholic microbes: a link between gut microbiota and depression?'. Neurogastroenterol & Motility, 25 (9):713-719 [DOI] [Details]
(2013)'Psychobiotics: a novel class of psychotropic'
Dinan TG, Stanton C, Cryan JF (2013) 'Psychobiotics: a novel class of psychotropic'. Biological psychiatry, 74 (10):720-726 [DOI] [Details]
(2013)'Lithium augmentation of the effects of desipramine in a mouse model of treatment-resistant depression: a role for hippocampal cell proliferation'
O'Leary OF, Zandy S, Dinan TG, Cryan JF (2013) 'Lithium augmentation of the effects of desipramine in a mouse model of treatment-resistant depression: a role for hippocampal cell proliferation'. Neuroscience, 228 :36-46 [DOI] [Details]
(2013)'Differential visceral nociceptive, behavioural and neurochemical responses to an immune challenge in the stress-sensitive Wistar Kyoto rat strain'
O' Mahony SM, Clarke G, McKernan DP, Bravo JA, Dinan TG, Cryan JF (2013) 'Differential visceral nociceptive, behavioural and neurochemical responses to an immune challenge in the stress-sensitive Wistar Kyoto rat strain'. Behavioral Brain Research, 253 :310-317 [DOI] [Details]
(2013)'GABAB receptor ligands do not modify conditioned fear responses in BALB/c mice'
Sweeney FF, O'Leary OF, Cryan JF (2013) 'GABAB receptor ligands do not modify conditioned fear responses in BALB/c mice'. Behavioral Brain Research, 256 :151-156 [DOI] [Details]
(2013)'In vitro investigations of the efficacy of cyclodextrin-siRNA complexes modified with lipid-PEG-Octaarginine: towards a formulation strategy for non-viral neuronal siRNA delivery'
O'Mahony AM, Desgranges S, Ogier J, Quinlan A, Devocelle M, Darcy R, Cryan JF, O'Driscoll CM (2013) 'In vitro investigations of the efficacy of cyclodextrin-siRNA complexes modified with lipid-PEG-Octaarginine: towards a formulation strategy for non-viral neuronal siRNA delivery'. Pharmaceutical research, 30 (4):1086-1098 [DOI] [Details]
(2013)'Alterations in prefrontal cortical serotonin and antidepressant-like behavior in a novel C3H/HeJxDBA/2J recombinant inbred mouse strain'
Browne CA, Clarke G, Hanke J, Dinan TG, Schwegler H, Yilmazer-Hanke DM, Cryan JF (2013) 'Alterations in prefrontal cortical serotonin and antidepressant-like behavior in a novel C3H/HeJxDBA/2J recombinant inbred mouse strain'. Behavioral Brain Research, 236 (1):283-288 [DOI] [Details]
(2013)'Crosstalk between interleukin-6 and corticotropin-releasing factor modulate submucosal plexus activity and colonic secretion'
O'Malley D, Cryan JF, Dinan TG (2013) 'Crosstalk between interleukin-6 and corticotropin-releasing factor modulate submucosal plexus activity and colonic secretion'. Brain Behav Immun, 30 :115-124 [DOI] [Details]
(2013)'The effects of mGlu7 receptor modulation in behavioural models sensitive to antidepressant action in two mouse strains'
O'Connor RM, Cryan JF (2013) 'The effects of mGlu7 receptor modulation in behavioural models sensitive to antidepressant action in two mouse strains'. Behavioural Pharmacology, 24 (2):105-113 [DOI] [Details]
(2013)'Antipsychotics and the gut microbiome: olanzapine-induced metabolic dysfunction is attenuated by antibiotic administration in the rat'
Davey KJ, Cotter PD, O'Sullivan O, Crispie F, Dinan TG, Cryan JF, O'Mahony SM (2013) 'Antipsychotics and the gut microbiome: olanzapine-induced metabolic dysfunction is attenuated by antibiotic administration in the rat'. Translational psychiatry, 3 [DOI] [Details]
(2013)'The microbiome-gut-brain axis during early life regulates the hippocampal serotonergic system in a sex-dependent manner'
Clarke G, Grenham S, Scully P, Fitzgerald P, Moloney RD, Shanahan F, Dinan TG, Cryan JF (2013) 'The microbiome-gut-brain axis during early life regulates the hippocampal serotonergic system in a sex-dependent manner'. Molecular psychiatry, 18 (6):666-673 [DOI] [Details]
(2013)'Non-viral nanosystems for gene and small interfering RNA delivery to the central nervous system: formulating the solution'
O'Mahony AM, Godinho BM, Cryan JF, O'Driscoll CM (2013) 'Non-viral nanosystems for gene and small interfering RNA delivery to the central nervous system: formulating the solution'. Journal of pharmaceutical sciences, 102 (10):3469-3484 [DOI] [Details]
(2013)'Disodium cromoglycate reverses colonic visceral hypersensitivity and influences colonic ion transport in a stress-sensitive rat strain'
Carroll SY, O'Mahony SM, Grenham S, Cryan JF, Hyland NP (2013) 'Disodium cromoglycate reverses colonic visceral hypersensitivity and influences colonic ion transport in a stress-sensitive rat strain'. Plos One, 8 (12) [DOI] [Details]
(2013)'Cationic and PEGylated Amphiphilic Cyclodextrins: Co-Formulation Opportunities for Neuronal Sirna Delivery'
O'Mahony AM, Ogier J, Darcy R, Cryan JF, O'Driscoll CM (2013) 'Cationic and PEGylated Amphiphilic Cyclodextrins: Co-Formulation Opportunities for Neuronal Sirna Delivery'. Plos One, 8 (6) [DOI] [Details]
(2013)'Unraveling the longstanding scars of early neurodevelopmental stress'
Cryan JF, Dinan TG (2013) 'Unraveling the longstanding scars of early neurodevelopmental stress'. Biological psychiatry, 74 (11):788-789 [DOI] [Details]
(2012)'Mind-altering microorganisms: the impact of the gut microbiota on brain and behaviour'
Cryan JF, Dinan TG (2012) 'Mind-altering microorganisms: the impact of the gut microbiota on brain and behaviour'. Nature Reviews Neuroscience, 13 (10):701-712 [DOI] [Details]
(2012)'A Distinct Profile of Tryptophan Metabolism along the Kynurenine Pathway Downstream of Toll-Like Receptor Activation in Irritable Bowel Syndrome'
Clarke G, McKernan DP, Gaszner G, Quigley EM, Cryan JF, Dinan TG (2012) 'A Distinct Profile of Tryptophan Metabolism along the Kynurenine Pathway Downstream of Toll-Like Receptor Activation in Irritable Bowel Syndrome'. Frontiers in pharmacology, 3 [DOI] [Details]
(2012)'Differential lipopolysaccharide-induced immune alterations in the hippocampus of two mouse strains: effects of stress'
Browne CA, O'Brien FE, Connor TJ, Dinan TG, Cryan JF (2012) 'Differential lipopolysaccharide-induced immune alterations in the hippocampus of two mouse strains: effects of stress'. Neuroscience, 225 :237-248 [DOI] [Details]
(2012)'Blockade of the GABA(B) receptor increases neurogenesis in the ventral but not dorsal adult hippocampus: relevance to antidepressant action'
Felice D, O'Leary OF, Pizzo RC, Cryan JF (2012) 'Blockade of the GABA(B) receptor increases neurogenesis in the ventral but not dorsal adult hippocampus: relevance to antidepressant action'. Neuropharmacology, 63 (8):1380-1388 [DOI] [Details]
(2012)'Click-modified cyclodextrins as nonviral vectors for neuronal siRNA delivery'
O'Mahony AM, Godinho BM, Ogier J, Devocelle M, Darcy R, Cryan JF, O'Driscoll CM (2012) 'Click-modified cyclodextrins as nonviral vectors for neuronal siRNA delivery'. ACS chemical neuroscience, 3 (10):744-752 [DOI] [Details]
(2012)'Bifidobacterium breve with a-linolenic acid and linoleic acid alters fatty acid metabolism in the maternal separation model of irritable bowel syndrome'
Barrett E, Fitzgerald P, Dinan TG, Cryan JF, Ross RP, Quigley EM, Shanahan F, Kiely B, Fitzgerald GF, O'Toole PW, Stanton C (2012) 'Bifidobacterium breve with a-linolenic acid and linoleic acid alters fatty acid metabolism in the maternal separation model of irritable bowel syndrome'. Plos One, 7 (11) [DOI] [Details]
(2012)'A click chemistry route to 2-functionalised PEGylated and cationic ß-cyclodextrins: co-formulation opportunities for siRNA delivery'
O'Mahony AM, Ogier J, Desgranges S, Cryan JF, Darcy R, O'Driscoll CM (2012) 'A click chemistry route to 2-functionalised PEGylated and cationic ß-cyclodextrins: co-formulation opportunities for siRNA delivery'. Organic & Biomolecular Chemistry, 10 (25):4954-4960 [DOI] [Details]
(2012)'Interleukin-6 modulates colonic transepithelial ion transport in the stress-sensitive wistar kyoto rat'
O'Malley D, Dinan TG, Cryan JF (2012) 'Interleukin-6 modulates colonic transepithelial ion transport in the stress-sensitive wistar kyoto rat'. Frontiers in pharmacology, 3 [DOI] [Details]
(2012)'Characterisation of cationic amphiphilic cyclodextrins for neuronal delivery of siRNA: effect of reversing primary and secondary face modifications'
O'Mahony AM, Doyle D, Darcy R, Cryan JF, O'Driscoll CM (2012) 'Characterisation of cationic amphiphilic cyclodextrins for neuronal delivery of siRNA: effect of reversing primary and secondary face modifications'. European Journal of Pharmaceutical Sciences, 47 (5):896-903 [DOI] [Details]
(2012)'Interleukin-6 modulates transepithelial ion transport in Wistar Kyoto rat distal colon'
O’Malley D, Dinan TG & Cryan JF (2012) 'Interleukin-6 modulates transepithelial ion transport in Wistar Kyoto rat distal colon'. Frontiers In Pharmacology, [Details]
(2011)'Enhanced peripheral toll-like receptor responses in psychosis: further evidence of a pro-inflammatory phenotype'
McKernan DP, Dennison U, Gaszner G, Cryan JF, Dinan TG (2011) 'Enhanced peripheral toll-like receptor responses in psychosis: further evidence of a pro-inflammatory phenotype'. Translational psychiatry, 1 [DOI] [Details]
(2012)'Characterisation of cationic amphiphilic cyclodextrins for neuronal delivery of siRNA: Effect of reversing primary and secondary face modifications'
O'Mahony AM, Doyle D, Darcy R, Cryan JF, O'Driscoll CM. (2012) 'Characterisation of cationic amphiphilic cyclodextrins for neuronal delivery of siRNA: Effect of reversing primary and secondary face modifications'. European Journal of Pharmaceutical Sciences, 47 (5):896-903 [DOI] [Full Text] [Details]
(2012)'Click-modified cyclodextrins as non-viral vectors for neuronal siRNA delivery'
O'Mahony, AM, Godinho, BMDC, Ogier, J, Devocelle, M, Darcy, R, Cryan, JF, O'Driscoll, CM (2012) 'Click-modified cyclodextrins as non-viral vectors for neuronal siRNA delivery'. ACS Chemical Neuroscience, 10 (3):744-752 [DOI] [Full Text] [Details]
(2012)'Bifidobacterium breve with alpha-Linolenic Acid and Linoleic Acid Alters Fatty Acid Metabolism in the Maternal Separation Model of Irritable Bowel Syndrome'
Barrett, E,Fitzgerald, P,Dinan, TG,Cryan, JF,Ross, RP,Quigley, EM,Shanahan, F,Kiely, B,Fitzgerald, GF,O'Toole, PW,Stanton, C (2012) 'Bifidobacterium breve with alpha-Linolenic Acid and Linoleic Acid Alters Fatty Acid Metabolism in the Maternal Separation Model of Irritable Bowel Syndrome'. Plos One, 7 [DOI] [Details]
(2012)'Blockade of the GABA(B) receptor increases neurogenesis in the ventral but not dorsal adult hippocampus: Relevance to antidepressant action'
Felice, D,O'Leary, OF,Pizzo, RC,Cryan, JF (2012) 'Blockade of the GABA(B) receptor increases neurogenesis in the ventral but not dorsal adult hippocampus: Relevance to antidepressant action'. Neuropharmacology, 63 :1380-1388 [DOI] [Details]
(2012)'Click-Modified Cyclodextrins as Nonviral Vectors for Neuronal siRNA Delivery'
O'Mahony, AM,Godinho, BMDC,Ogier, J,Devocelle, M,Darcy, R,Cryan, JF,O'Driscoll, CM (2012) 'Click-Modified Cyclodextrins as Nonviral Vectors for Neuronal siRNA Delivery'. ACS Chemical Neuroscience, 3 :744-752 [DOI] [Details]
(2012)'Genetic vs. pharmacological inactivation of COMT influences cannabinoid-induced expression of schizophrenia-related phenotypes'
O'Tuathaigh, CMP,Clarke, G,Walsh, J,Desbonnet, L,Petit, E,O'Leary, C,Tighe, O,Clarke, N,Karayiorgou, M,Gogos, JA,Dinan, TG,Cryan, JF,Waddington, JL (2012) 'Genetic vs. pharmacological inactivation of COMT influences cannabinoid-induced expression of schizophrenia-related phenotypes'. International Journal of Neuropsychopharmacology, 15 :1331-1342 [DOI] [Details]
(2012)'Schizophrenia patients with a history of childhood trauma have a pro-inflammatory phenotype'
Dennison, U,McKernan, D,Cryan, J,Dinan, T (2012) 'Schizophrenia patients with a history of childhood trauma have a pro-inflammatory phenotype'. Psychological medicine, 42 :1865-1871 [DOI] [Details]
(2013)'In vitro investigations of the efficacy of Cyclodextrin-siRNA complexes modified with Lipid-PEG-Octaarginine: Towards A Formulation Strategy for Effective Neuronal siRNA Delivery'
O'Mahony, AM., Desgranges S., Ogier JR., Quinlan A., Devocelle M., Darcy, R., Cryan, JF and O'Driscoll, CM. (2013) 'In vitro investigations of the efficacy of Cyclodextrin-siRNA complexes modified with Lipid-PEG-Octaarginine: Towards A Formulation Strategy for Effective Neuronal siRNA Delivery'. Pharmaceutical Research, 30 (4):1086-1098 [DOI] [Full Text] [Details]
(2013)'Self-assembling Modified β-Cyclodextrin Nanoparticles as Neuronal siRNA Delivery Vectors: Focus on Huntington's Disease'
Godinho BM, Ogier JR, Darcy R, O'Driscoll CM, Cryan JF. (2013) 'Self-assembling Modified β-Cyclodextrin Nanoparticles as Neuronal siRNA Delivery Vectors: Focus on Huntington's Disease'. Molecular Pharmaceutics, 10 :640-649 [DOI] [Details]
(2013)'Cyclodextrins for Non-Viral Gene and siRNA Delivery'
O'Mahony AM., O’Neill MJ., Godinho BMDC., Darcy, R., Cryan, JF and; O'Driscoll, CM. (2013) 'Cyclodextrins for Non-Viral Gene and siRNA Delivery'. Pharmaceutical Nanotechnology, 1 :6-14 [Full Text] [Details]
(2013)'Towards translational rodent models of depression'
O'Leary OF, Cryan JF (2013) 'Towards translational rodent models of depression'. Cell Tissue Research, 354 (1):141-145 [Details]
(2010)'A Gut Feeling about GABA: Focus on GABA(B) Receptors'
Hyland NP and Cryan JF (2010) 'A Gut Feeling about GABA: Focus on GABA(B) Receptors'. Frontiers In Pharmacology,   [DOI] [Details]
(2011)'Enhanced peripheral toll-like receptor responses in psychosis: further evidence of a pro-inflammatory phenotype'
McKernan, DP,Dennison, U,Gaszner, G,Cryan, JF,Dinan, TG (2011) 'Enhanced peripheral toll-like receptor responses in psychosis: further evidence of a pro-inflammatory phenotype'. Translational Psychiatry, 1 [DOI] [Details]
(2011)'BDNF expression in the hippocampus of maternally separated rats: does Bifidobacterium breve 6330 alter BDNF levels?'
O'Sullivan, E,Barrett, E,Grenham, S,Fitzgerald, P,Stanton, C,Ross, RP,Quigley, EMM,Cryan, JF,Dinan, TG (2011) 'BDNF expression in the hippocampus of maternally separated rats: does Bifidobacterium breve 6330 alter BDNF levels?'. Beneficial microbes, 2 :199-207 [DOI] [Details]
(2012)'Using the rat forced swim test to assess antidepressant-like activity in rodents'
Slattery, DA,Cryan, JF (2012) 'Using the rat forced swim test to assess antidepressant-like activity in rodents'. Nature Protocols, 7 :1009-1014 [DOI] [Details]
(2012)'Rodent models of colorectal distension'
O'Mahony SM, Tramullas M, Fitzgerald P, Cryan JF (2012) 'Rodent models of colorectal distension'. Current protocols in neuroscience / editorial board, Jacqueline N. Crawley ... [et al.], Chapter 9 [DOI] [Details]
(2012)'Chronic stress-induced alterations in mouse colonic 5-HT and defecation responses are strain dependent'
Julio-Pieper, M,O'Mahony, CM,Clarke, G,Bravo, JA,Dinan, TG,Cryan, JF (2012) 'Chronic stress-induced alterations in mouse colonic 5-HT and defecation responses are strain dependent'. Stress (Amsterdam, Netherlands), 15 :218-226 [DOI] [Details]
(2012)'Lithium-induced effects on adult hippocampal neurogenesis are topographically segregated along the dorso-ventral axis of stressed mice'
O'Leary, OF,O'Connor, RM,Cryan, JF (2012) 'Lithium-induced effects on adult hippocampal neurogenesis are topographically segregated along the dorso-ventral axis of stressed mice'. Neuropharmacology, 62 :247-255 [DOI] [Details]
(2012)'Blockade of the GABA(B) receptor increases neurogenesis in the ventral but not dorsal adult hippocampus: Relevance to antidepressant action'
Felice D, O'Leary OF, Pizzo RC, Cryan JF. (2012) 'Blockade of the GABA(B) receptor increases neurogenesis in the ventral but not dorsal adult hippocampus: Relevance to antidepressant action'. Neuropharmacology, 63 (8):1380-1388 [DOI] [Details]
(2013)'Hippocampal group III mGlu receptor mRNA levels are not altered in specific mouse models of stress, depression and antidepressant action'
O'Connor RM, Pusceddu M, O'Leary OF, Savignac HM, Bravo JF, El Yacoubi M, Vaugeois JM, Dinan TG, Cryan JF. (2013) 'Hippocampal group III mGlu receptor mRNA levels are not altered in specific mouse models of stress, depression and antidepressant action'. Pharmacology Biochemistry and Behavior, 103 (3):561-567 [DOI] [Details]
(2013)'Lithium Augmentation of the effects of Desipramine in a Mouse Model of Treatment-Resistant Depression: A Role for Hippocampal Cell Proliferation'
O'Leary OF, Zandy S, Dinan TG, Cryan JF (2013) 'Lithium Augmentation of the effects of Desipramine in a Mouse Model of Treatment-Resistant Depression: A Role for Hippocampal Cell Proliferation'. Neuroscience, 228 :36-46 [DOI] [Details]
(2013)'Alterations in prefrontal cortical serotonin and antidepressant-like behavior in a novel C3H/HeJxDBA/2J recombinant inbred mouse strain'
Browne, CA,Clarke, G,Hanke, J,Dinan, TG,Schwegler, H,Yilmazer-Hanke, DM,Cryan, JF (2013) 'Alterations in prefrontal cortical serotonin and antidepressant-like behavior in a novel C3H/HeJxDBA/2J recombinant inbred mouse strain'. Behavioural Brain Research, 236 :283-288 [DOI] [Details]
(2004)'Norepinephrine-deficient mice lack responses to antidepressant drugs, including selective serotonin reuptake inhibitors'
Cryan JF, O'Leary OF, Jin SH, Friedland JC, Ouyang M, Hirsch BR, Page ME, Dalvi A, Thomas SA, Lucki I; (2004) 'Norepinephrine-deficient mice lack responses to antidepressant drugs, including selective serotonin reuptake inhibitors'. Proceedings of The National Academy of Sciences of The United States of America, 101 (21):8186-8191 [DOI] [Details]
(2010)'A Gut Feeling about GABA: Focus on GABA(B) Receptors'
Hyland NP, Cryan JF (2010) 'A Gut Feeling about GABA: Focus on GABA(B) Receptors'. Frontiers In Pharmacology, 1 [DOI] [Details]
(2011)'Altered expression and secretion of colonic Interleukin-6 in a stress-sensitive animal model of brain-gut axis dysfunction'
O'Malley, D,Dinan, TG,Cryan, JF; (2011) 'Altered expression and secretion of colonic Interleukin-6 in a stress-sensitive animal model of brain-gut axis dysfunction'. The Journal of Immunology, 235 :48-55 [DOI] [Details]
(2012)'Lithium-induced effects on adult hippocampal neurogenesis are topographically segregated along the dorso-ventral axis of stressed mice'
O'Leary OF, O'Connor RM, Cryan JF; (2012) 'Lithium-induced effects on adult hippocampal neurogenesis are topographically segregated along the dorso-ventral axis of stressed mice'. Neuropharmacology, 62 (1):247-255 [DOI] [Details]
(2011)'Genetic vs. pharmacological inactivation of COMT influences cannabinoid-induced expression of schizophrenia-related phenotypes'
O'Tuathaigh CM, Clarke G, Walsh J, Desbonnet L, Petit E, O'Leary C, Tighe O, Clarke N, Karayiorgou M, Gogos JA, Dinan TG, Cryan JF, Waddington JL (2011) 'Genetic vs. pharmacological inactivation of COMT influences cannabinoid-induced expression of schizophrenia-related phenotypes'. International Journal of Neuropsychopharmacology, :1-12 [DOI] [Details]
(2011)'BDNF expression in the hippocampus of maternally separated rats: does Bifidobacterium breve 6330 alter BDNF levels?'
O'Sullivan E, Barrett E, Grenham S, Fitzgerald P, Stanton C, Ross RP, Quigley EM, Cryan JF, Dinan TG (2011) 'BDNF expression in the hippocampus of maternally separated rats: does Bifidobacterium breve 6330 alter BDNF levels?'. Beneficial microbes, 2 (3):199-207 [DOI] [Details]
(2011)'Do interactions between stress and immune responses lead to symptom exacerbations in irritable bowel syndrome?'
O'Malley D, Quigley EM, Dinan TG, Cryan JF (2011) 'Do interactions between stress and immune responses lead to symptom exacerbations in irritable bowel syndrome?'. Brain Behav Immun, 25 (7):1333-1341 [DOI] [Details]
(2011)'Behavioral satiety sequence in a genetic mouse model of obesity: effects of ghrelin receptor ligands'
Finger, BC,Dinan, TG,Cryan, JF; (2011) 'Behavioral satiety sequence in a genetic mouse model of obesity: effects of ghrelin receptor ligands'. Behavioural Pharmacology, 22 :624-632 [DOI] [Details]
(2011)'Ingestion of Lactobacillus strain regulates emotional behavior and central GABA receptor expression in a mouse via the vagus nerve'
Bravo, JA,Forsythe, P,Chew, MV,Escaravage, E,Savignac, HM,Dinan, TG,Bienenstock, J,Cryan, JF; (2011) 'Ingestion of Lactobacillus strain regulates emotional behavior and central GABA receptor expression in a mouse via the vagus nerve'. Proceedings of The National Academy of Science Usa, 108 :16050-16055 [DOI] [Details]
(2011)'The effects of gabapentin in two animal models of co-morbid anxiety and visceral hypersensitivity'
O'Mahony, SM,Coelho, AM,Fitzgerald, P,Lee, K,Winchester, W,Dinan, TG,Cryan, JF; (2011) 'The effects of gabapentin in two animal models of co-morbid anxiety and visceral hypersensitivity'. European Journal of Pharmacology, 667 :169-174 [DOI] [Details]
(2011)'Brain-gut-microbe communication in health and disease'
Grenham S, Clarke G, Cryan JF, Dinan TG (2011) 'Brain-gut-microbe communication in health and disease'. Frontiers in Physiology, 2 [DOI] [Details]
(2011)'Ingestion of Lactobacillus strain regulates emotional behavior and central GABA receptor expression in a mouse via the vagus nerve'
Bravo JA, Forsythe P, Chew MV, Escaravage E, Savignac HM, Dinan TG, Bienenstock J, Cryan JF (2011) 'Ingestion of Lactobacillus strain regulates emotional behavior and central GABA receptor expression in a mouse via the vagus nerve'. Proceedings of The National Academy of Sciences of The United States of America, 108 (38):16050-16055 [DOI] [Details]
(2011)'High-fat diet selectively protects against the effects of chronic social stress in the mouse'
Finger BC, Dinan TG, Cryan JF (2011) 'High-fat diet selectively protects against the effects of chronic social stress in the mouse'. Science (New York, N.Y.), 192 :351-360 [DOI] [Details]
(2011)'The age of anxiety: role of animal models of anxiolytic action in drug discovery'
Cryan JF, Sweeney FF (2011) 'The age of anxiety: role of animal models of anxiolytic action in drug discovery'. British Journal of Pharmacology, 164 (4):1129-1161 [DOI] [Details]
(2011)'Resistance to early-life stress in mice: effects of genetic background and stress duration'
Savignac HM, Dinan TG, Cryan JF (2011) 'Resistance to early-life stress in mice: effects of genetic background and stress duration'. Behavioral Neuroscience, 5 [DOI] [Details]
(2011)'Altered peripheral toll-like receptor responses in the irritable bowel syndrome'
McKernan DP, Gaszner G, Quigley EM, Cryan JF, Dinan TG (2011) 'Altered peripheral toll-like receptor responses in the irritable bowel syndrome'. Pharmacology & Therapeutics, 33 (9):1045-1052 [DOI] [Details]
(2011)'Gut Memories: Towards a Cognitive Neurobiology of Irritable Bowel Syndrome'
Kennedy, P.J., G. Clarke, G., Quigley, E.M.M., Groeger., J.A., Dinan., T.G., Cryan. J.F. ; (2011) 'Gut Memories: Towards a Cognitive Neurobiology of Irritable Bowel Syndrome'. Neuroscience and Biobehavioral Reviews, [Details]
(2011)'Altered expression and secretion of colonic interleukin-6 in a stress-sensitive animal model of brain-gut axis dysfunction'
O'Malley D, Dinan TG, Cryan JF (2011) 'Altered expression and secretion of colonic interleukin-6 in a stress-sensitive animal model of brain-gut axis dysfunction'. Journal of Neuroimmunology, 235 (1-2):48-55 [DOI] [Details]
(2011)'Chronic psychosocial stress induces visceral hyperalgesia in mice'
Tramullas M, Dinan TG, Cryan JF (2011) 'Chronic psychosocial stress induces visceral hyperalgesia in mice'. Stress (Amsterdam, Netherlands), [DOI] [Details]
(2011)'Increased sensitivity to the effects of chronic social defeat stress in an innately anxious mouse strain'
Savignac HM, Finger BC, Pizzo RC, O'Leary OF, Dinan TG, Cryan JF; (2011) 'Increased sensitivity to the effects of chronic social defeat stress in an innately anxious mouse strain'. Neuroscience, 192 :524-536 [DOI] [Details]
(2012)'Chronic stress-induced alterations in mouse colonic 5-HT and defecation responses are strain dependent'
Julio-Pieper M, O'Mahony CM, Clarke G, Bravo JA, Dinan TG, Cryan JF (2012) 'Chronic stress-induced alterations in mouse colonic 5-HT and defecation responses are strain dependent'. Stress (Amsterdam, Netherlands), [DOI] [Details]
(2012)'Gut memories: towards a cognitive neurobiology of irritable bowel syndrome'
Kennedy PJ, Clarke G, Quigley EM, Groeger JA, Dinan TG, Cryan JF (2012) 'Gut memories: towards a cognitive neurobiology of irritable bowel syndrome'. Neuroscience and Biobehavioral Reviews, 36 (1):310-340 [DOI] [Details]
(2012)'Dynamic 5-HT(2C) Receptor Editing in a Mouse Model of Obesity'
Schellekens H, Clarke G, Jeffery IB, Dinan TG, Cryan JF (2012) 'Dynamic 5-HT(2C) Receptor Editing in a Mouse Model of Obesity'. Plos One, 7 (3) [DOI] [Full Text] [Details]
(2012)'Phenotypic effects of repeated psychosocial stress during adolescence in mice mutant for the schizophrenia risk gene neuregulin-1: A putative model of gene×environment interaction'
Desbonnet L, O'Tuathaigh C, Clarke G, O'Leary C, Petit E, Clarke N, Tighe O, Lai D, Harvey R, Cryan JF, Dinan TG, Waddington JL (2012) 'Phenotypic effects of repeated psychosocial stress during adolescence in mice mutant for the schizophrenia risk gene neuregulin-1: A putative model of gene×environment interaction'. Brain Behav Immun, [Details]
(2012)'Schizophrenia patients with a history of childhood trauma have a pro-inflammatory phenotype'
Dennison U, McKernan D, Cryan J, Dinan T (2012) 'Schizophrenia patients with a history of childhood trauma have a pro-inflammatory phenotype'. Psychological medicine, :1-7 [DOI] [Details]
(2012)'Gender-dependent consequences of chronic olanzapine in the rat: effects on body weight, inflammatory, metabolic and microbiota parameters'
Davey KJ, O'Mahony SM, Schellekens H, O'Sullivan O, Bienenstock J, Cotter PD, Dinan TG, Cryan JF (2012) 'Gender-dependent consequences of chronic olanzapine in the rat: effects on body weight, inflammatory, metabolic and microbiota parameters'. Pharmacology, 221 (1):155-169 [DOI] [Details]
(2012)'Diet-induced obesity blunts the behavioural effects of ghrelin: studies in a mouse-progressive ratio task'
Finger BC, Dinan TG, Cryan JF (2012) 'Diet-induced obesity blunts the behavioural effects of ghrelin: studies in a mouse-progressive ratio task'. Pharmacology, 220 (1):173-181 [DOI] [Details]
(2012)'A Distinct Profile of Tryptophan Metabolism along the Kynurenine Pathway Downstream of Toll-Like Receptor Activation in Irritable Bowel Syndrome'
Clarke, G; McKernan, D; Gaszner, G; Quigley, E; Cryan, J; Dinan, T (2012) 'A Distinct Profile of Tryptophan Metabolism along the Kynurenine Pathway Downstream of Toll-Like Receptor Activation in Irritable Bowel Syndrome'. Frontiers In Pharmacology, 3:90 [DOI] [Details]
(2013)'The Microbiome-Gut-Brain Axis During Early-Life Regulates the Hippocampal Serotonergic System in a Sex-Dependent Manner'
Clarke, G; Grenham, S; Scully, P; Fitzgerald, P; Moloney, R; Shanahan, F; Dinan, T; Cryan, J (2013) 'The Microbiome-Gut-Brain Axis During Early-Life Regulates the Hippocampal Serotonergic System in a Sex-Dependent Manner'. Molecular Psychiatry, 18 (6):666-673 [Details]
(2012)'Phenotypic effects of repeated psychosocial stress during adolescence in mice mutant for the schizophrenia risk gene neuregulin-1: A putative model of gene x environment interaction'
Desbonnet, L,O'Tuathaigh, C,Clarke, G,O'Leary, C,Petit, E,Clarke, N,Tighe, O,Lai, D,Harvey, R,Cryan, JF,Dinan, TG,Waddington, JL (2012) 'Phenotypic effects of repeated psychosocial stress during adolescence in mice mutant for the schizophrenia risk gene neuregulin-1: A putative model of gene x environment interaction'. Brain Behav Immun, 26 :660-671 [DOI] [Details]
(2012)'Chronic psychosocial stress induces visceral hyperalgesia in mice'
Tramullas, M,Dinan, TG,Cryan, JF (2012) 'Chronic psychosocial stress induces visceral hyperalgesia in mice'. Stress (Amsterdam, Netherlands), 15 :281-292 [DOI] [Details]
(2012)'Early-life stress induces visceral hypersensitivity in mice'
Moloney, RD,O'Leary, OF,Felice, D,Bettler, B,Dinan, TG,Cryan, JF (2012) 'Early-life stress induces visceral hypersensitivity in mice'. Neuroscience Letters, 512 :99-102 [DOI] [Details]
(2012)'An effective dietary method for chronic tryptophan depletion in two mouse strains illuminates a role for 5-HT in nesting behaviour'
Browne, CA,Clarke, G,Dinan, TG,Cryan, JF (2012) 'An effective dietary method for chronic tryptophan depletion in two mouse strains illuminates a role for 5-HT in nesting behaviour'. Neuropharmacology, 62 :1903-1915 [DOI] [Details]
(2012)'Menstrual Cycle Influences Toll-Like Receptor Responses'
Dennison, U,McKernan, DP,Scully, P,Clarke, G,Cryan, J,Dinan, T (2012) 'Menstrual Cycle Influences Toll-Like Receptor Responses'. Neuroimmunomodulation, 19 :171-179 [DOI] [Details]
(2012)'The temporal impact of chronic intermittent psychosocial stress on high-fat diet-induced alterations in body weight'
Finger BC, Dinan TG, Cryan JF (2012) 'The temporal impact of chronic intermittent psychosocial stress on high-fat diet-induced alterations in body weight'. Psychoneuroendocrinology, 37 (6):729-741 [DOI] [Details]
(2012)'Little things on which happiness depends: microRNAs as novel therapeutic targets for the treatment of anxiety and depression'
O'Connor RM, Dinan TG, Cryan JF (2012) 'Little things on which happiness depends: microRNAs as novel therapeutic targets for the treatment of anxiety and depression'. Molecular Psychiatry, 17 (4):359-376 [DOI] [Details]
(2012)'Early-life stress induces visceral hypersensitivity in mice'
Moloney RD, O'Leary OF, Felice D, Bettler B, Dinan TG, Cryan JF (2012) 'Early-life stress induces visceral hypersensitivity in mice'. Neuroscience Letters, 512 (2):99-102 [DOI] [Details]
(2012)'Regulation of the stress response by the gut microbiota: Implications for psychoneuroendocrinology'
Dinan TG, Cryan JF (2012) 'Regulation of the stress response by the gut microbiota: Implications for psychoneuroendocrinology'. Psychoneuroendocrinology, [DOI] [Details]
(2012)'Early-life stress induces visceral hypersensitivity in mice'
Moloney RD, O'Leary OF, Felice D, Bettler B, Dinan TG, Cryan JF. (2012) 'Early-life stress induces visceral hypersensitivity in mice'. Neuroscience Letters, 512 (2):99-102 [Details]
(2012)'An effective dietary method for chronic tryptophan depletion in two mouse strains illuminates a role for 5-HT in nesting behaviour'
Browne CA, Clarke G, Dinan TG, Cryan JF (2012) 'An effective dietary method for chronic tryptophan depletion in two mouse strains illuminates a role for 5-HT in nesting behaviour'. Neuropharmacology, [DOI] [Details]
(2012)'Review article: probiotics for the treatment of irritable bowel syndrome - focus on lactic acid bacteria'
Clarke G, Cryan JF, Dinan TG, Quigley EM (2012) 'Review article: probiotics for the treatment of irritable bowel syndrome - focus on lactic acid bacteria'. Alimentary Pharmacology And Therapeutics, 35 (4):403-413 [DOI] [Details]
(2012)'Inhibition of P-glycoprotein Enhances Transport of the Antidepressant Imipramine across the Blood-Brain Barrier: Microdialysis Studies in the Conscious Freely Moving Rat'
O'Brien FE, Clarke G, Fitzgerald P, Dinan TG, Griffin BT, Cryan JF (2012) 'Inhibition of P-glycoprotein Enhances Transport of the Antidepressant Imipramine across the Blood-Brain Barrier: Microdialysis Studies in the Conscious Freely Moving Rat'. British Journal of Pharmacology, [DOI] [Details]
(2012)'Menstrual Cycle Influences Toll-Like Receptor Responses'
Dennison U, McKernan DP, Scully P, Clarke G, Cryan J, Dinan T (2012) 'Menstrual Cycle Influences Toll-Like Receptor Responses'. Neuroimmunomodulation, 19 (3):171-179 [DOI] [Details]
(2011)'Interactions between antidepressants and P-glycoprotein at the blood-brain barrier: Clinical significance of in vitro and in vivo findings'
O'Brien FE, Dinan TG, Griffin BT, Cryan JF; (2011) 'Interactions between antidepressants and P-glycoprotein at the blood-brain barrier: Clinical significance of in vitro and in vivo findings'. British Journal of Pharmacology, [DOI] [Details]
(2011)'Exciting Times beyond the Brain: Metabotropic Glutamate Receptors in Peripheral and Non-Neural Tissues'
Julio-Pieper M, Flor PJ, Dinan TG, Cryan JF; (2011) 'Exciting Times beyond the Brain: Metabotropic Glutamate Receptors in Peripheral and Non-Neural Tissues'. Pharmacological reviews, [DOI] [Details]
(2011)'The microbiome-gut-brain axis: from bowel to behavior'
Cryan JF, O'Mahony SM; (2011) 'The microbiome-gut-brain axis: from bowel to behavior'. Neurogastroenterology and Motility, 23 (3):187-192 [DOI] [Details]
(2011)'Differential stress-induced alterations in tryptophan hydroxylase activity and serotonin turnover in two inbred mouse strains'
Browne CA, Clarke G, Dinan TG, Cryan JF; (2011) 'Differential stress-induced alterations in tryptophan hydroxylase activity and serotonin turnover in two inbred mouse strains'. Neuropharmacology, 60 (4):683-691 [DOI] [Details]
(2011)'Alterations in the central CRF system of two different rat models of comorbid depression and functional gastrointestinal disorders'
Bravo, JA,Dinan, TG,Cryan, JF; (2011) 'Alterations in the central CRF system of two different rat models of comorbid depression and functional gastrointestinal disorders'. International Journal of Neuropsychopharmacology, 14 :666-683 [DOI] [Details]
(2011)'Is there altered sensitivity to ghrelin-receptor ligands in leptin-deficient mice?: importance of satiety state and time of day'
Finger BC, Schellekens H, Dinan TG, Cryan JF; (2011) 'Is there altered sensitivity to ghrelin-receptor ligands in leptin-deficient mice?: importance of satiety state and time of day'. Psychopharmacology, [DOI] [Details]
(2010)'Riluzole Normalizes Early-Life Stress-induced Visceral Hypersensitivity in Rats: Role of Spinal Glutamate Reuptake Mechanisms'
Gosselin, RD; O'Connor, RM; Tramullas, M; Julio-Pieper, M; Dinan, TG; Cryan, JF; (2010) 'Riluzole Normalizes Early-Life Stress-induced Visceral Hypersensitivity in Rats: Role of Spinal Glutamate Reuptake Mechanisms'. Gastroenterology, [DOI] [Details]
(2010)'Lean mean fat reducing ghrelin machine: hypothalamic ghrelin and ghrelin receptors as therapeutic targets in obesity'
Schellekens, H; Dinan, TG; Cryan, JF; (2010) 'Lean mean fat reducing ghrelin machine: hypothalamic ghrelin and ghrelin receptors as therapeutic targets in obesity'. Neuropharmacology, 58 (1):2-16 [DOI] [Details]
(2010)'Colorectal distension-induced prefrontal cortex activation in the Wistar-Kyoto rat: implications for irritable bowel syndrome'
Gibney, SM; Gosselin, RD; Dinan, TG; Cryan, JF; (2010) 'Colorectal distension-induced prefrontal cortex activation in the Wistar-Kyoto rat: implications for irritable bowel syndrome'. Neuroscience, 165 (3):675-683 [DOI] [Details]
(2010)'Metabotropic glutamate receptor 7: At the interface of cognition and emotion'
O'Connor, RM; Finger, BC; Flor, PJ; Cryan, JF; (2010) 'Metabotropic glutamate receptor 7: At the interface of cognition and emotion'. European Journal of Pharmacology, [DOI] [Details]
(2010)'Transient inactivation of the infralimbic cortex induces antidepressant-like effects in the rat'
Slattery, DA; Neumann, I; Cryan, JF; (2010) 'Transient inactivation of the infralimbic cortex induces antidepressant-like effects in the rat'. Journal of Psychopharmacology, [DOI] [Details]
(2010)'Neonatal maternal separation in the rat impacts on the stress responsivity of central corticotropin-releasing factor receptors in adulthood'
O'Malley, D; Dinan, TG; Cryan, JF; (2010) 'Neonatal maternal separation in the rat impacts on the stress responsivity of central corticotropin-releasing factor receptors in adulthood'. Psychopharmacology, [DOI] [Details]
(2010)'Restraint stress-induced brain activation patterns in two strains of mice differing in their anxiety behaviour'
O'Mahony, CM; Sweeney, FF; Daly, E; Dinan, TG; Cryan, JF; (2010) 'Restraint stress-induced brain activation patterns in two strains of mice differing in their anxiety behaviour'. Behavioural Brain Research, 213 :148-154 [DOI] [Details]
(2010)'5-HT2B receptors modulate visceral hypersensitivity in a stress-sensitive animal model of brain-gut axis dysfunction'
O'Mahony, SM; Bulmer, DC; Coelho, AM; Fitzgerald, P; Bongiovanni, C; Lee, K; Winchester, W; Dinan, TG; Cryan, JF; (2010) '5-HT2B receptors modulate visceral hypersensitivity in a stress-sensitive animal model of brain-gut axis dysfunction'. Neurogastroenterology and Motility, 22 [DOI] [Details]
(2010)'A Sensitive Period of Mice Inhibitory System to Neonatal GABA Enhancement by Vigabatrin is Brain Region Dependent'
Levav-Rabkin, T; Melamed, O; Clarke, G; Farber, M; Cryan, JF; Dinan, TG; Grossman, Y; Golan, HM; (2010) 'A Sensitive Period of Mice Inhibitory System to Neonatal GABA Enhancement by Vigabatrin is Brain Region Dependent'. Neuropsychopharmacology, 35 :1138-1154 [DOI] [Details]
(2010)'GABAB receptors and depression. Current status'
Cryan JF, Slattery DA; (2010) 'GABAB receptors and depression. Current status'. Advances In Pharmacology, 58 :427-451 [DOI] [Details]
(2010)'IBs: an epigenetic perspective'
Dinan, Timothy G; Cryan, John; Shanahan, Fergus; Keeling, PW Napoleon; Quigley, Eamonn MM; (2010) 'IBs: an epigenetic perspective'. Nature Reviews Gastroenterology & Hepatology, 7 (8):465-471 [DOI] [Details]
(2010)'Strain differences in the neurochemical response to chronic restraint stress in the rat: Relevance to depression'
O'Mahony CM, Clarke G, Gibney S, Dinan TG, Cryan JF; (2010) 'Strain differences in the neurochemical response to chronic restraint stress in the rat: Relevance to depression'. Pharmacology Biochemistry and Behavior, [DOI] [Details]
(2010)'A Gut Feeling about GABA: Focus on GABAB receptors'
Hyland, NP; Cryan, JF; (2010) 'A Gut Feeling about GABA: Focus on GABAB receptors'. Frontiers in Pharmacology,   [DOI] [Details]
(2011)'Maternal separation as a model of brain-gut axis dysfunction'
O'Mahony, SM; Hyland, NP; Dinan, TG; Cryan, JF; (2011) 'Maternal separation as a model of brain-gut axis dysfunction'. Psychopharmacology,   [DOI] [Details]
(2010)'Colonic Soluble Mediators from the Maternal Separation Model of Irritable Bowel Syndrome Activate Submucosal Neurons via an Interleukin-6-dependent Mechanism'
O'Malley D, Liston M, Hyland NP, Dinan TG, Cryan JF; (2010) 'Colonic Soluble Mediators from the Maternal Separation Model of Irritable Bowel Syndrome Activate Submucosal Neurons via an Interleukin-6-dependent Mechanism'. American Journal of Physiology - Gastrointestinal and Liver Physiology, [DOI] [Details]
(2010)'Marked elevations in pro-inflammatory polyunsaturated fatty acid metabolites in females with irritable bowel syndrome'
Clarke, G; Fitzgerald, P; Hennessy, AA; Cassidy, EM; Quigley, EMM; Ross, P; Stanton, C; Cryan, JF; Dinan, TG; (2010) 'Marked elevations in pro-inflammatory polyunsaturated fatty acid metabolites in females with irritable bowel syndrome'. Journal of Lipid Research, 51 :1186-1192 [DOI] [Details]
(2010)'Differential stress-induced alterations of colonic corticotropin-releasing factor receptors in the Wistar Kyoto rat'
O'Malley, D; Julio-Pieper, M; Gibney, SM; Gosselin, RD; Dinan, TG; Cryan, JF; (2010) 'Differential stress-induced alterations of colonic corticotropin-releasing factor receptors in the Wistar Kyoto rat'. Neurogastroenterology and Motility, 22 :301-311 [DOI] [Details]
(2010)'Neuroscience. A glutamate pathway to faster-acting antidepressants?'
Cryan JF, O'Leary OF; (2010) 'Neuroscience. A glutamate pathway to faster-acting antidepressants?'. Science, 329 (5994):913-914 [DOI] [Details]
(2010)'Progressive ratio responding in an obese mouse model: Effects of fenfluramine'
Finger BC, Dinan TG, Cryan JF; (2010) 'Progressive ratio responding in an obese mouse model: Effects of fenfluramine'. Neuropharmacology, 59 (7-8):619-626 [DOI] [Details]
(2010)'Alterations in colonic corticotropin-releasing factor receptors in the maternally separated rat model of irritable bowel syndrome: Differential effects of acute psychological and physical stressors'
O'Malley, D; Dinan, TG; Cryan, JF; (2010) 'Alterations in colonic corticotropin-releasing factor receptors in the maternally separated rat model of irritable bowel syndrome: Differential effects of acute psychological and physical stressors'. Peptides, 31 :662-670 [DOI] [Details]
(2010)'The effects of repeated social interaction stress on behavioural and physiological parameters in a stress-sensitive mouse strain'
Savignac, HM; Hyland, NP; Dinan, TG; Cryan, JF; (2010) 'The effects of repeated social interaction stress on behavioural and physiological parameters in a stress-sensitive mouse strain'. Behavioural Brain Research, [DOI] [Details]
(2010)'The probiotic Bifidobacterium infantis 35624 displays visceral antinociceptive effects in the rat'
McKernan, DP; Fitzgerald, P; Dinan, TG; Cryan, JF; (2010) 'The probiotic Bifidobacterium infantis 35624 displays visceral antinociceptive effects in the rat'. Neurogastroenterology and Motility, [DOI] [Details]
(2010)'Comparison of Hippocampal Metabotropic Glutamate Receptor 7 (mGlu(7)) mRNA Levels in Two Animal Models of Depression'
O'Mahony, CM; Bravo, J; Dinan, TG; Cryan, JF; (2010) 'Comparison of Hippocampal Metabotropic Glutamate Receptor 7 (mGlu(7)) mRNA Levels in Two Animal Models of Depression'. Neuroscience Letters, [DOI] [Details]
(2010)'Therapeutic targeting in the silent era: advances in non-viral siRNA delivery'
Guo, J; Fisher, KA; Darcy, R; Cryan, JF; O'Driscoll, C; (2010) 'Therapeutic targeting in the silent era: advances in non-viral siRNA delivery'. Molecular Biosystems, 6 (7):1143-1161 [DOI] [Full Text] [Details]
(2010)'Leptin-deficient mice retain normal appetitive spatial learning yet exhibit marked increases in anxiety-related behaviours'
Finger, BC; Dinan, TG; Cryan JF; (2010) 'Leptin-deficient mice retain normal appetitive spatial learning yet exhibit marked increases in anxiety-related behaviours'. Psychopharmacology, [DOI] [Details]
(2009)'Region specific decrease in glial fibrillary acidic protein immunoreactivity in the brain of a rat model of depression'
Gosselin RD, Gibney S, O'Malley D, Dinan TG, Cryan JF; (2009) 'Region specific decrease in glial fibrillary acidic protein immunoreactivity in the brain of a rat model of depression'. Neuroscience, 159 (2):915-925 [DOI] [Details]
(2009)'Toll-Like Receptor mRNA Expression Is Selectively Increased in the Colonic Mucosa of Two Animal Models Relevant to Irritable Bowel Syndrome'
McKernan, DP,Nolan, A,Brint, EK,O'Mahony, SM,Hyland, NP,Cryan, JF,Dinan, TG; (2009) 'Toll-Like Receptor mRNA Expression Is Selectively Increased in the Colonic Mucosa of Two Animal Models Relevant to Irritable Bowel Syndrome'. Plos One, 4 [DOI] [Details]
(2009)'Chain reactions: Early-life stress alters the metabolic profile of plasma polyunsaturated fatty acids in adulthood'
Clarke, G,O'Mahony, SM,Hennessy, AA,Ross, P,Stanton, C,Cryan, JF,Dinan, TG; (2009) 'Chain reactions: Early-life stress alters the metabolic profile of plasma polyunsaturated fatty acids in adulthood'. Behavioural Brain Research, 205 :319-321 [DOI] [Details]
(2009)'REGION SPECIFIC DECREASE IN GLIAL FIBRILLARY ACIDIC PROTEIN IMMUNOREACTIVITY IN THE BRAIN OF A RAT MODEL OF DEPRESSION'
Gosselin, RD,Gibney, S,O'Malley, D,Dinan, TG,Cryan, JF; (2009) 'REGION SPECIFIC DECREASE IN GLIAL FIBRILLARY ACIDIC PROTEIN IMMUNOREACTIVITY IN THE BRAIN OF A RAT MODEL OF DEPRESSION'. Neuroscience, 159 :915-925 [DOI] [Details]
(2009)'Tryptophan degradation in irritable bowel syndrome: evidence of indoleamine 2,3-dioxygenase activation in a male cohort. BMC Gastroenterol'
Clarke, G.,Fitzgerald, P.,Cryan, J. F.,Cassidy, E. M.,Quigley, E. M.,Dinan, T. G.; (2009) 'Tryptophan degradation in irritable bowel syndrome: evidence of indoleamine 2,3-dioxygenase activation in a male cohort. BMC Gastroenterol'. BMC Gastroenterol, 9   [Details]
(2009)'A mouse model for visualization of GABA(B) receptors'
Casanova E, Guetg N, Vigot R, Seddik R, Julio-Pieper M, Hyland NP, Cryan JF, Gassmann M, Bettler B; (2009) 'A mouse model for visualization of GABA(B) receptors'. Genesis, 47 (9):595-602 [DOI] [Details]
(2009)'Killing the Blues: a role for cellular suicide (apoptosis) in depression and the antidepressant response?'
McKernan DP, Dinan TG, Cryan JF; (2009) 'Killing the Blues: a role for cellular suicide (apoptosis) in depression and the antidepressant response?'. Progress In Neurobiology, 88 (4):246-263 [DOI] [Details]
(2009)'Update on smoking cessation therapies'
Glynn DA, Cryan JF, Kent P, Flynn RA, Kennedy MP; (2009) 'Update on smoking cessation therapies'. Advances In Therapy, 26 (4):369-382 [DOI] [Details]
(2009)'Verapamil in treatment resistant depression: a role for the P-glycoprotein transporter?'
Clarke G, O'Mahony SM, Cryan JF, Dinan TG; (2009) 'Verapamil in treatment resistant depression: a role for the P-glycoprotein transporter?'. Human Psychopharmacology, 24 (3):217-223 [DOI] [Details]
(2009)'Irritable bowel syndrome: towards biomarker identification'
Clarke, G; Quigley, EM; Cryan, JF; Dinan, TG; (2009) 'Irritable bowel syndrome: towards biomarker identification'. Trends In Molecular Medicine, 15 (10):478-489 [DOI] [Details]
(2009)'A Distinct Subset of Submucosal Mast Cells Undergoes Hyperplasia Following Neonatal Maternal Separation: A Role In Visceral Hypersensitivity?'
Hyland, NP, Julio-Pieper, M, O'Mahony, SM, Bulmer, DC, Lee, K, Quigley, EM, Dinan, TG, Cryan, JF; (2009) 'A Distinct Subset of Submucosal Mast Cells Undergoes Hyperplasia Following Neonatal Maternal Separation: A Role In Visceral Hypersensitivity?'. Gut, (7):1029-1030 [DOI] [Details]
(2008)'The Rostral Anterior Cingulate Cortex Modulates The Efficiency of Amygdala-Dependent Fear Learning'
Bissiere, S, Plachta, N, Hoyer, D, McAllister, KH, Olpe, HR, Grace, AA, Cryan, JF; (2008) 'The Rostral Anterior Cingulate Cortex Modulates The Efficiency of Amygdala-Dependent Fear Learning'. Biological Psychiatry, 63 (9):821-831 [DOI] [Details]
(2008)'Enhanced cholinergic-mediated increase in the pro-inflammatory cytokine IL-6 in irritable bowel syndrome: role of muscarinic receptors'
Dinan TG, Clarke G, Quigley EM, Scott LV, Shanahan F, Cryan J, Cooney J, Keeling PW; (2008) 'Enhanced cholinergic-mediated increase in the pro-inflammatory cytokine IL-6 in irritable bowel syndrome: role of muscarinic receptors'. The American Journal of Gastroenterology, 103 (10):2570-2576 [DOI] [Details]
(2008)'Tryptophan catabolism in females with irritable bowel syndrome: relationship to interferon-gamma, severity of symptoms and psychiatric co-morbidity'
Fitzgerald, P,Eugene, MC,Clarke, G,Scully, P,Barry, S,Eamonn, MMQ,Shanahan, F,Cryan, J,Timothy, GD; (2008) 'Tryptophan catabolism in females with irritable bowel syndrome: relationship to interferon-gamma, severity of symptoms and psychiatric co-morbidity'. Neurogastroenterology and Motility, 20 :1291-1297 [DOI] [Details]
(2008)'Evaluation of the anxiolytic-like profile of the GABA(B) receptor positive modulator CGP7930 in rodents'
Jacobson, LH,Cryan, JF; (2008) 'Evaluation of the anxiolytic-like profile of the GABA(B) receptor positive modulator CGP7930 in rodents'. Neuropharmacology, 54 :854-862 [DOI] [Details]
(2008)'mGluR7 facilitates extinction of aversive memories and controls amygdala plasticity'
Fendt, M,Schmid, S,Thakker, DR,Jacobson, LH,Yamamoto, R,Mitsukawa, K,Maier, R,Natt, F,Husken, D,Kelly, PH,McAllister, KH,Hoyer, D,van der Putten, H,Cryan, JF,Flor, PJ; (2008) 'mGluR7 facilitates extinction of aversive memories and controls amygdala plasticity'. Molecular Psychiatry, 13 :970-979 [DOI] [Details]
(2008)'Specific roles of GABAB(1) receptor isoforms in cognition'
Jacobson LH, Kelly PH, Bettler B, Kaupmann K and Cryan JF ; (2008) 'Specific roles of GABAB(1) receptor isoforms in cognition'. Behavioural brain research, (181):158-162 [Details]
(2008)'Selective activation of metabotropic G-protein-coupled glutamate 7 receptor elicits anxiolytic-like effects in mice by modulating GABAergic neurotransmission'
Stachowicz K, Brañski P, Kłak K, van der Putten H, Cryan JF, Flor PJ, Andrzej P; (2008) 'Selective activation of metabotropic G-protein-coupled glutamate 7 receptor elicits anxiolytic-like effects in mice by modulating GABAergic neurotransmission'. Behavioural Pharmacology, [Details]
(2008)'Activation of mGluR7 alters amygdala plasticity and facilitates extinction of fear memories'
5. Fendt, M., Schmid, S., Thakker, D.R., Jacobson, L.H., Yamamota, R. Mitsukawa, K. Maier, R, McAllister, K.H., Hoyer, D. van der Putten, H. Cryan JF and Flor, P.J; (2008) 'Activation of mGluR7 alters amygdala plasticity and facilitates extinction of fear memories'. Molecular Psychiatry, [Details]
(2008)'Early life stress alters behaviour, immunity and microbiota: implications for irritable bowel syndrome and psychiatric illnesses'
2. O' Mahony SM, Marchesi J, Scully P, Codling C, Ceolho A-M, Quigley EMM, Cryan JF, and Dinan TG; (2008) 'Early life stress alters behaviour, immunity and microbiota: implications for irritable bowel syndrome and psychiatric illnesses'. Biological Psychiatry, [Details]
(2008)'Mglur7 Facilitates Extinction of Aversive Memories and Controls Amygdala Plasticity'
Fendt, M, Schmid, S, Thakker, DR, Jacobson, LH, Yamamoto, R, Mitsukawa, K, Maier, R, Natt, F, Husken, D, Kelly, PH, McAllister, KH, Hoyer, D, van der Putten, H, Cryan, JF, Flor, PJ; (2008) 'Mglur7 Facilitates Extinction of Aversive Memories and Controls Amygdala Plasticity'. Molecular Psychiatry, 13 (10):970-979 [DOI] [Details]
(2007)'Amyloid Precursor Protein Knockdown By Sirna Impairs Spontaneous Alternation In Adult Mice'
Senechal, Y, Kelly, PH, Cryan, JF, Natt, F, Dev, KK; (2007) 'Amyloid Precursor Protein Knockdown By Sirna Impairs Spontaneous Alternation In Adult Mice'. Journal of Neurochemistry, 102 (6):1928-1940 [DOI] [Details]
(2007)'Evaluation of Reward Processes In An Animal Model of Depression'
Slattery, DA, Markou, A, Cryan, JF; (2007) 'Evaluation of Reward Processes In An Animal Model of Depression'. Psychopharmacology, 190 (4):555-568 [DOI] [Details]
(2007)'GABAB Receptor positive modulation decreases selective molecular and behavioral effects of cocaine'
Lhuillier L., Mombereau C., *Cryan JF and *Kaupmann, K. ; (2007) 'GABAB Receptor positive modulation decreases selective molecular and behavioral effects of cocaine'. Neuropsychopharmacology, (32):388-398 [Details]
(2007)'Animal models of mood disorders: recent developments'
Cryan, JF,Slattery, DA; (2007) 'Animal models of mood disorders: recent developments'. Current Opinion In Psychiatry, 20 :1-7 [Details]
(2007)'Feeling strained? Influence of genetic background on depression-related behavior in mice: A review'
Jacobson LH and Cryan JF; (2007) 'Feeling strained? Influence of genetic background on depression-related behavior in mice: A review'. Behavior Genetics, (37):171-213 [Details]
(2007)'Behavioural evaluation of mice deficient in GABAB(1) receptor isoforms in tests of unconditioned anxiety'
Jacobson LH, Kaupmann, K., Bettler., Cryan JF ; (2007) 'Behavioural evaluation of mice deficient in GABAB(1) receptor isoforms in tests of unconditioned anxiety'. Psychopharmacology, (190):541-553 [Details]
(2007)'Antidepressant-like effects of the novel, slelective, 5-HT2C receptor agonist WAY-163909 in rodents'
Rosenzweig-Lipson S, Sabb A, Stack G, Mitchell PJ, Lucki I, Malberg J, Grauer S, Brennan J, Cryan JF, Dunlop J, Barrett J, Marquis KL; (2007) 'Antidepressant-like effects of the novel, slelective, 5-HT2C receptor agonist WAY-163909 in rodents'. Psychopharmacology, :159-170 [Details]
(2007)'Neurogenetics and Behaviour: From Basic Processes to Neuropsychiatric Disorders'
Cryan, JF, Driscoll, P, Waddington, JL; (2007) 'Neurogenetics and Behaviour: From Basic Processes to Neuropsychiatric Disorders'. Neuroscience & Biobehavioral Reviews, (1):1-2 [DOI] [Details]
(2007)'Concise Clinical Pharmacology'
Sahm L., and Cryan J.F.; (2007) 'Concise Clinical Pharmacology'. Irish Pharmacy Journal, [Details]
(2007)'Emerging use of non-viral RNA interference in the brain'
Cryan JF, Thakker DR, Hoyer D; (2007) 'Emerging use of non-viral RNA interference in the brain'. Biochemical Society Transactions, 35 (Pt 2):411-415 [DOI] [Details]
(2006)'The Rostral Anterior Cingulate Cortex Modulates Depression But Not Anxiety-Related Behaviour In The Rat'
Bissiere, S, McAllister, KH, Olpe, HR, Cryan, JF; (2006) 'The Rostral Anterior Cingulate Cortex Modulates Depression But Not Anxiety-Related Behaviour In The Rat'. Behavioural Brain Research, 175 (1):195-199 [DOI] [Details]
(2006)'Gaba(B(1)) Receptor Subunit Isoforms Exert A Differential Influence On Baseline But Not Gaba(B) Receptor Agonist-Induced Changes In Mice'
Jacobson, LH, Bettler, B, Kaupmann, K, Cryan, JF; (2006) 'Gaba(B(1)) Receptor Subunit Isoforms Exert A Differential Influence On Baseline But Not Gaba(B) Receptor Agonist-Induced Changes In Mice'. Journal of Pharmacology and Experimental Therapeutics, 319 (3):1317-1326 [DOI] [Details]
(2006)'The role of GABAB receptors in depression and the antidepressant response'
Slattery DA, Cryan JF; (2006) 'The role of GABAB receptors in depression and the antidepressant response'. Drug Development Research, :477-494 [Details]
(2006)'GABA(B(1)) receptor isoforms differentially mediate the acquisition and extinction of aversive taste memories'
Jacobson, LH,Kelly, PH,Bettler, B,Kaupmann, K,Cryan, JF; (2006) 'GABA(B(1)) receptor isoforms differentially mediate the acquisition and extinction of aversive taste memories'. The Journal of Neuroscience, 26 :8800-8803 [DOI] [Details]
(2006)'GABA(B(1)) receptor subunit isoforms exert a differential influence on baseline but not GABA(B) receptor agonist-induced changes in mice'
Jacobson, LH,Bettler, B,Kaupmann, K,Cryan, JF; (2006) 'GABA(B(1)) receptor subunit isoforms exert a differential influence on baseline but not GABA(B) receptor agonist-induced changes in mice'. Journal of Pharmacology and Experimental Therapeutics, 319 :1317-1326 [DOI] [Details]
(2006)'Differential compartmentalization and distinct functions of GABAB receptor variants'
Vigot R, Barbieri S, Bräuner-Osborne H, Turecek R, Shigemoto R, Zhang YP, Luján R, Jacobson LH, Biermann B, Fritschy JM, Vacher CM, Müller M, Sansig G, Guetg N, Cryan JF, Kaupmann K, Gassmann M, Oertner TG and Bettler B; (2006) 'Differential compartmentalization and distinct functions of GABAB receptor variants'. Neuron, (50):589-601 [Details]
(2006)'Interfering with the brain: The utility of siRNA to unravel the pathophysiology of psychiatric and neurological disorders'
Thakker DR, Hoyer D, Cryan JF; (2006) 'Interfering with the brain: The utility of siRNA to unravel the pathophysiology of psychiatric and neurological disorders'. Pharmacology &Amp; Therapeutics, (109):413-438 [Details]
(2006)'Global down-regulation of gene expression in the brain using RNA interference, with emphasis on monamine transporters and GPCRs: implications for target characterization in psychiatric and neurological disorders'
Hoyer D, Thakker DR, Natt F, Maier R, Huesken D, Müller M, Flor PJ, van der Putten H, Schmutz M, Bilbe, G. and Cryan JF; (2006) 'Global down-regulation of gene expression in the brain using RNA interference, with emphasis on monamine transporters and GPCRs: implications for target characterization in psychiatric and neurological disorders'. Journal of Receptors and Signal Transduction, (26):527-547 [Details]
(2006)'GABAB(1) receptor isoforms differentially mediate the acquisition and the extinction of aversive taste learning'
Jacobson LH, Kelly PH, Bettler B, Kaupmann K and Cryan JF; (2006) 'GABAB(1) receptor isoforms differentially mediate the acquisition and the extinction of aversive taste learning'. Journal of Neuroscience, (26):8800-8803 [Details]
(2006)'Metabotropic glutamate receptor subtype 7 ablation causes dysregulation of the HPA axis and increases hippocampal BDNF protein levels; implications for stress-related psychiatric disorders'
Mitsukawa K, Mombereau C, Loetscher E, Uzunov D, van der Putten H, Flor PJ, Cryan JF; (2006) 'Metabotropic glutamate receptor subtype 7 ablation causes dysregulation of the HPA axis and increases hippocampal BDNF protein levels; implications for stress-related psychiatric disorders'. Neuropsychopharmacology, :1112-1122 [Details]
(2006)'Concomitant deficits in working memory and fear extinction are functionally dissociated from reduced anxiety in mGluR7-deficient mice'
Callaerts-Vegh Z, Beckers T, Baeyens F, Callaerts PF, Cryan JF, Molnar E, D'Hooge R; (2006) 'Concomitant deficits in working memory and fear extinction are functionally dissociated from reduced anxiety in mGluR7-deficient mice'. Journal of Neuroscience, :6573-6582 [Full Text] [Details]
(2005)'The GABAB receptor positive modulator GS39783 and the GABAB receptor agonist decrease the rewarding effects of cocaine: Intracranial self-stimulation studies in the rat'
Slattery DA, Markou A. and Cryan JF; (2005) 'The GABAB receptor positive modulator GS39783 and the GABAB receptor agonist decrease the rewarding effects of cocaine: Intracranial self-stimulation studies in the rat'. Neuropsychopharmacology, 30 (11):2065-2072 [Details]
(2005)'siRNA-mediated knockdown of the serotonin transporter in the adult mouse brain. '
Thakker DR, Natt F, Husken D, van der Putten H, Maier R, Hoyer D, Cryan JF; (2005) 'siRNA-mediated knockdown of the serotonin transporter in the adult mouse brain. '. Molecular Psychiatry, 10 (8):782-789 [Details]
(2005)'Short and long-term administration of reboxetine, fluoxetine and moclobemide differentially alter behaviour in a modified rat forced swim test'
Cryan JF, Page M.E. and Lucki I.; (2005) 'Short and long-term administration of reboxetine, fluoxetine and moclobemide differentially alter behaviour in a modified rat forced swim test'. Psychopharmacology, 6 (*):1-10 [Details]
(2005)'Don't worry 'B' happy!: a role for GABA(B) receptors in anxiety and depression. '
Cryan JF, Kaupmann K. ; (2005) 'Don't worry 'B' happy!: a role for GABA(B) receptors in anxiety and depression. '. Trends In Pharmacological Sciences, 26 (1):36-43 [Details]
(2005)'Differential sensitivity to the motor and hypothermic effects of the GABA B receptor agonist baclofen in various mouse strains. '
Jacobson LH, Cryan JF; (2005) 'Differential sensitivity to the motor and hypothermic effects of the GABA B receptor agonist baclofen in various mouse strains. '. Psychopharmacology, 179 (3):688-699 [Details]
(2005)'The tail suspension test as a model for assessing antidepressant activity: review of pharmacological and genetic studies in mice. '
Cryan JF, Mombereau C, Vassout A. ; (2005) 'The tail suspension test as a model for assessing antidepressant activity: review of pharmacological and genetic studies in mice. '. Neuroscience & Biobehavioral Reviews, 29 (4-5):571-625 [Details]
(2005)'Blockade of the Group I metabotropic glutamate receptor mGluR5 decreases basal and stress induced increases in cortical norepinephrine in the rat'
Page, M.E., Szeliga, P.J., Gasparini, F. and Cryan, JF ; (2005) 'Blockade of the Group I metabotropic glutamate receptor mGluR5 decreases basal and stress induced increases in cortical norepinephrine in the rat'. Psychopharmacology, (179):240-246 [Details]
(2005)'GABAB receptor-mediated antidepressant-like effects are serotonin dependent'
Slattery, D., Desrayaud, S. and Cryan JF ; (2005) 'GABAB receptor-mediated antidepressant-like effects are serotonin dependent'. Journal of Pharmacology and Experimental Therapeutics, (312):290-296 [Details]
(2005)'The modified rat forced swim test: Assessing serotonergic influences on depression-related behavior'
Cryan JF, Valentino RJ, Lucki I; (2005) 'The modified rat forced swim test: Assessing serotonergic influences on depression-related behavior'. Neuroscience & Biobehavioral Reviews, 29 (4-5):547-569 [Details]
(2005)'Altered anxiety and depression-related behaviour in mice lacking GABAB(2) receptor subunits. '
Mombereau C, Kaupmann K, Gassmann M, Bettler B, van der Putten H, Cryan JF. ; (2005) 'Altered anxiety and depression-related behaviour in mice lacking GABAB(2) receptor subunits. '. Neuroreport, 28 (16):307-310 [Details]
(2005)'Blockade of the mGlu5 receptor decreases basal and stress-induced cortical norepinephrine in rodents. '
Page ME, Szeliga P, Gasparini F, Cryan JF; (2005) 'Blockade of the mGlu5 receptor decreases basal and stress-induced cortical norepinephrine in rodents. '. Psychopharmacology, 179 (1):240-246 [Details]
(2005)'The first selective mGluR7 agonist, AMN082 activates receptor signaling via a novel allosteric site and modulates stress parameters in vivo'
Mitsukawa K, Yamamoto R, Ofner S, Nozulak J, Pescott O, Lukic S, Stoehr N, Mombereau C, Kuhn R, McAllister KH, van der Putten H, Cryan JF, Flor PJ; (2005) 'The first selective mGluR7 agonist, AMN082 activates receptor signaling via a novel allosteric site and modulates stress parameters in vivo'. Proceedings of The National Academy of Sciences of The United States of America, :18712-18717 [Details]
(2005)'The ascent of mouse: Using mice to model human depression and anxiety'
Cryan JF, Holmes A; (2005) 'The ascent of mouse: Using mice to model human depression and anxiety'. Nature Reviews Drug Discovery, :775-790 [Details]
(2004)'Genetic and pharmacological evidence of a key role for GABAB receptors in the modulation of anxiety and antidepressant-like behaviour'
Mombereau C., Kaupmann K., Froestl, W. Sansig, G. van der Putten H. and Cryan, JF; (2004) 'Genetic and pharmacological evidence of a key role for GABAB receptors in the modulation of anxiety and antidepressant-like behaviour'. Neuropsychopharmacology, 29 (6):1050-1062 [Details]
(2004)'Redistribution of GABAB(1) protein and atypical GABAB responses in GABAB(2)-deficient mice. '
Gassmann M., Shaban H., Vigot R., Sansig G., Haller C., Barbieri S., Humeau Y., Schuler V., Muller M., Kinzel B., Klebs K., Schmutz M., Froestl W., Heid J., Kelly P.H., Gentry C., Jaton A.L., Van der Putten H., Mombereau C., Lecourtier L., Mosbacher J., Cryan JF, Fritschy J.M., Luthi A., Kaupmann K., Bettler B. ; (2004) 'Redistribution of GABAB(1) protein and atypical GABAB responses in GABAB(2)-deficient mice. '. Journal of Neuroscience, 24 (27):6086-6097 [Details]
(2004)'In search of a depressed mouse: utility of models for studying depression-related behavior in genetically modified mice'
Cryan JF, Mombereau C.; (2004) 'In search of a depressed mouse: utility of models for studying depression-related behavior in genetically modified mice'. Molecular Psychiatry, 9 (4):326-357 [Details]
(2004)'Norepinephrine-deficient mice lack responses to antidepressant drugs, including selective serotonin reuptake inhibitors'
Cryan, JF, O’Leary O., Hirsch, B.R., Jin S-H, Page M.E., Dalvi A., Thomas S.A. and Lucki I.; (2004) 'Norepinephrine-deficient mice lack responses to antidepressant drugs, including selective serotonin reuptake inhibitors'. Proceedings of The National Acadamy of Sciences, 101 (*):8186-8191 [Details]
(2004)'Altered response to benzodiazepine anxiolytics in mice lacking GABAB(1) receptors'
Mombereau C., Kaupmann K., van der Putten H., and Cryan JF; (2004) 'Altered response to benzodiazepine anxiolytics in mice lacking GABAB(1) receptors'. European Journal of Pharmacology, 497 (1):119-120 [Details]
(2004)'Behavioral characterization of the novel GABAB receptor-positive modulator GS39783 (N,N'-dicyclopentyl-2-methylsulfanyl-5-nitro-pyrimidine-4,6-diamine): anxiolytic-like activity without side effects associated with baclofen or benzodiazepines'
Cryan JF, Kelly PH, Chaperon F, Gentsch C, Froestl W, Mombereau C, Lingenhoehl K, Bettler B, Kaupmann K, Spooren WPJM; (2004) 'Behavioral characterization of the novel GABAB receptor-positive modulator GS39783 (N,N'-dicyclopentyl-2-methylsulfanyl-5-nitro-pyrimidine-4,6-diamine): anxiolytic-like activity without side effects associated with baclofen or benzodiazepines'. Journal of Pharmacology and Experimental Therapeutics, :952-963 [Details]
(2003)'The antidepressant bupropion enhances brain reward function and reverses affective and somatic aspects of nicotine withdrawal'
Cryan J.F, Bruijnzeel A.W., Skjei K.S. and Markou A.; (2003) 'The antidepressant bupropion enhances brain reward function and reverses affective and somatic aspects of nicotine withdrawal'. Psychopharmacology, 168 (*):347-358 [Details]
(2003)'Withdrawal from chronic amphetamine induces depression-like behavioural effects in rodents'
Cryan J.F., Hoyer D. and Markou A.; (2003) 'Withdrawal from chronic amphetamine induces depression-like behavioural effects in rodents'. Biological Psychiatry, 54 (*):49-58 [Details]
(2003)'Antidepressant and anxiolytic-like effects in mice lacking the group III metabotropic glutamate receptor mGluR7'
Cryan J.F., Kelly P.H., Sansig G., Flor P.J. and van Der Putten H.; (2003) 'Antidepressant and anxiolytic-like effects in mice lacking the group III metabotropic glutamate receptor mGluR7'. European Journal of Neuroscience, 17 (11):2409-2417 [Details]
(2003)'Non-nicotinic neuropharmacological strategies for Smoking Cessation'
Cryan J.F., Gasparini F., van Heeke G. and Markou A.; (2003) 'Non-nicotinic neuropharmacological strategies for Smoking Cessation'. Drug Discovery Today, 8 (22):1025-1034 [Details]
(2003)'Specific ã-Hydroxybutyrate (GHB) binding sites but loss of pharmacological effects of GHB in GABA-B(1) receptor deficient mice'
Kaupmann K., Cryan J.F., Wellendorph P., Mombereau C., Sansig G., Klebs K., Schmutz, M., Froestl, W. van der Putten, H., Mosbacher, J., Bräuner-Osborne, H., Waldmeier, P., and Bettler, B.; (2003) 'Specific ã-Hydroxybutyrate (GHB) binding sites but loss of pharmacological effects of GHB in GABA-B(1) receptor deficient mice'. European Journal of Neuroscience, 18 (10):2722-2730 [Details]
(2002)'Neurochemical and behavioral characterization of the novel 5-HT1A receptor partial agonist/serotonin reuptake inhibitor EMD 68843'
Page M.E., Cryan J.F., Sulivan A., Dalvi A. and Lucki I.; (2002) 'Neurochemical and behavioral characterization of the novel 5-HT1A receptor partial agonist/serotonin reuptake inhibitor EMD 68843'. The Journal of Pharmacology and Experimental Therapeuti, 302 (3):1220-1227 [Details]
(2002)'Noradrenergic lesions differentially alter the antidepressant-like effects of reboxetine'
Cryan, J.F. Page M.E., and Lucki. I.; (2002) 'Noradrenergic lesions differentially alter the antidepressant-like effects of reboxetine'. European Journal of Pharmacology, 436 (3):197-205 [Details]
(2002)'CREB is essential for upregulation of brain derived neurotrophic factor transcription, but not behavioral or endocrine responses to antidepressant drugs'
Conti A.C., Cryan J.F., Dalvi A., Lucki I. and Blendy J.A.; (2002) 'CREB is essential for upregulation of brain derived neurotrophic factor transcription, but not behavioral or endocrine responses to antidepressant drugs'. Journal of Neuroscience, 15 (22):3262-3268 [Details]
(2002)'Assessing antidepressant activity in rodents: recent developments and future needs. '
Cryan J.F., Markou A., Lucki I. ; (2002) 'Assessing antidepressant activity in rodents: recent developments and future needs. '. Trends In Pharmacological Sciences, 23 (5):238-245 [Details]
(2001)'Use of dopamine-beta-hydroxylase-deficient mice to determine the role of norepinephrine in the mechanism of action of antidepressant drugs. '
Cryan J.F., Dalvi A., Hirsch B.R., Jin, S-H, Lucki , I. and Thomas, S.A.; (2001) 'Use of dopamine-beta-hydroxylase-deficient mice to determine the role of norepinephrine in the mechanism of action of antidepressant drugs. '. The Journal of Pharmacology and Experimental Therapeuti, 298 (2):651-657 [Details]
(2000)'Antidepressant-like behavioral effects mediated by 5-Hydroxytryptamine(2C) receptors'
Cryan J.F. and Lucki I.; (2000) 'Antidepressant-like behavioral effects mediated by 5-Hydroxytryptamine(2C) receptors'. The Journal of Pharmacology and Experimental Therapeuti, 295 (3):1120-1126 [Details]
(2000)'Pindolol augmentation of antidepressants: a review and rationale. '
Olver J.S., Cryan J.F., Burrows G.D. and Norman T.R.; (2000) 'Pindolol augmentation of antidepressants: a review and rationale. '. Australian and New Zealand Journal of Psychiatry, 34 (1):71-79 [Details]
(2000)'5-HT1A and Beyond- The role of serotonin and its receptors in depression and the antidepressant response'
Cryan J.F. and Leonard B.E.; (2000) '5-HT1A and Beyond- The role of serotonin and its receptors in depression and the antidepressant response'. Human Psychopharmacology, 15 (2):113-135 [Details]
(2000)'Characterization of d-fenfluramine-induced hypothermia- Evidence for multiple sites of action'
Cryan J.F., Harkin A., Kelly J.P. and Leonard B.E.; (2000) 'Characterization of d-fenfluramine-induced hypothermia- Evidence for multiple sites of action'. European Journal of Pharmacology, 390 (3):275-285 [Details]
(1999)'Metyrapone displays antidepressant-like properties in preclinical paradigms'
Healy D.G., Harkin A. Cryan J.F., Kelly J.P. and Leonard B.E.; (1999) 'Metyrapone displays antidepressant-like properties in preclinical paradigms'. Psychopharmacology, 145 (3):303-308 [Details]
(1999)'Onset of the effects of the 5-HT1A antagonist, WAY-100635, alone, and in combination with paroxetine, on olfactory bulbectomy and 8-OH-DPAT-induced changes in the rat. '
Cryan J.F., McGrath C., Leonard B.E. and Norman T.R.; (1999) 'Onset of the effects of the 5-HT1A antagonist, WAY-100635, alone, and in combination with paroxetine, on olfactory bulbectomy and 8-OH-DPAT-induced changes in the rat. '. Pharmacology Biochemistry and Behavior, 63 (2):333-338 [Details]
(1999)'Comparative effects of serotonergic agonists with varying efficacy at the 5-HT1A receptor on core body temperature: Modification by the selective 5-HT1A receptor antagonist WAY-100635'
Cryan J.F., Kelliher P., Kelly J.P. and Leonard B.E.; (1999) 'Comparative effects of serotonergic agonists with varying efficacy at the 5-HT1A receptor on core body temperature: Modification by the selective 5-HT1A receptor antagonist WAY-100635'. Journal of Psychopharmacology, 13 (3):278-283 [Details]
(1998)'Combining pindolol and paroxetine in an animal model of chronic antidepressant action - Can early onset of action be detected?'
Cryan J.F., McGrath C., Leonard B.E. and Norman T.R.; (1998) 'Combining pindolol and paroxetine in an animal model of chronic antidepressant action - Can early onset of action be detected?'. European Journal of Pharmacology, 352 (1):23-28 [Details]
(1997)'The effects of the 5-HT1A agonist flesinoxan, in three paradigms for assessing antidepressant potential in the rat. '
Cryan J.F., Redmond A.M., Kelly J.P. and Leonard B.E.; (1997) 'The effects of the 5-HT1A agonist flesinoxan, in three paradigms for assessing antidepressant potential in the rat. '. European Neuropsychopharmacology, 7 (2):109-114 [Details]
(2014)'Strain differences in stress-induced changes in central CRF1 receptor expression'
O’Malley D, Julio-Pieper M, Dinan TG & Cryan JF (2014) 'Strain differences in stress-induced changes in central CRF1 receptor expression'. Neuroscience Letters, 21 (561):192-197 [Details]
(1996)'Does the serenic eltoprazine have antidepressant potential? -An investigation in three rodent paradigms'
Cryan J.F., Redmond A.M., Kelly J.P. and Leonard B.E.; (1996) 'Does the serenic eltoprazine have antidepressant potential? -An investigation in three rodent paradigms'. Medical Science Research, 24 (*):719-720 [Details]
(2014)'Differential visceral pain sensitivity and colonic morphology in four common laboratory rat strains'
O’Malley D, Julio-Pieper M, O’Mahony, SM, Dinan TG & Cryan JF (2014) 'Differential visceral pain sensitivity and colonic morphology in four common laboratory rat strains'. Experimental Physiology, 99 (2):359-367 [Details]
(2013)'Milk protein hydrolysates activate 5-HT2C serotonin receptors: influence of the starting substrate and isolation of bioactive fractions'
Nongonierma, AB,Schellekens, H,Dinan, TG,Cryan, JF,FitzGerald, RJ (2013) 'Milk protein hydrolysates activate 5-HT2C serotonin receptors: influence of the starting substrate and isolation of bioactive fractions'. Food & Function, 4 :728-737 [DOI] [Details]
(2013)'Disodium Cromoglycate Reverses Colonic Visceral Hypersensitivity and Influences Colonic Ion Transport in a Stress-Sensitive Rat Strain'
Carroll, SY,O'Mahony, SM,Grenham, S,Cryan, JF,Hyland, NP (2013) 'Disodium Cromoglycate Reverses Colonic Visceral Hypersensitivity and Influences Colonic Ion Transport in a Stress-Sensitive Rat Strain'. Plos One, 8 [DOI] [Full Text] [Details]
(2013)'Effects of the Intestinal Microbiota on Behavior and Brain Biochemistry'
Barrett, E,Dinan, TG,Cryan, JF,Quigley, EMM,Shanahan, F,O'Toole, PW,Fitzgerald, GF,Stanton, C,Ross, RP,Guarino, A,Quigley, EMM,Walker, WA (2013) 'Effects of the Intestinal Microbiota on Behavior and Brain Biochemistry'. Probiotic Bacteria And Their Effect On Human Health And Well-Being, 107 :56-63 [DOI] [Details]
(2011)'Resistance to early-life stress in mice: effects of genetic background and stress duration'
Savignac, HM,Dinan, TG,Cryan, JF (2011) 'Resistance to early-life stress in mice: effects of genetic background and stress duration'. Frontiers In Behavioral Neuroscience, 5 [DOI] [Details]
(2013)'The microbiome-gut-brain axis during early life regulates the hippocampal serotonergic system in a sex-dependent manner'
Clarke, G,Grenham, S,Scully, P,Fitzgerald, P,Moloney, RD,Shanahan, F,Dinan, TG,Cryan, JF (2013) 'The microbiome-gut-brain axis during early life regulates the hippocampal serotonergic system in a sex-dependent manner'. Molecular Psychiatry, 18 :666-673 [DOI] [Details]
(2013)'GABA(B) receptor ligands do not modify conditioned fear responses in BALB/c mice'
Sweeney, FF,O'Leary, OF,Cryan, JF (2013) 'GABA(B) receptor ligands do not modify conditioned fear responses in BALB/c mice'. Behavioural Brain Research, 256 :151-156 [DOI] [Details]
(2013)'Crosstalk between interleukin-6 and corticotropin-releasing factor modulate submucosal plexus activity and colonic secretion'
O'Malley D, Cryan JF, Dinan TG (2013) 'Crosstalk between interleukin-6 and corticotropin-releasing factor modulate submucosal plexus activity and colonic secretion'. Brain Behav Immun, doi:pii: S0889-1591(13)00081-0. 10.1016/j.bbi.2013.01.078. [Epub ahead of print] [Details]
(2013)'In Vitro Investigations of the Efficacy of Cyclodextrin-siRNA Complexes Modified with Lipid-PEG-Octaarginine: Towards a Formulation Strategy for Non-viral Neuronal siRNA Delivery'
O'Mahony, AM,Desgranges, S,Ogier, J,Quinlan, A,Devocelle, M,Darcy, R,Cryan, JF,O'Driscoll, CM (2013) 'In Vitro Investigations of the Efficacy of Cyclodextrin-siRNA Complexes Modified with Lipid-PEG-Octaarginine: Towards a Formulation Strategy for Non-viral Neuronal siRNA Delivery'. Pharmaceutical Research, 30 :1086-1098 [DOI] [Details]
(2013)'Semagacestat, a gamma-secretase inhibitor, activates the growth hormone secretagogue (GHS-R1a) receptor'
Schellekens, H,McNamara, O,Dinan, TG,McCarthy, JV,McGlacken, GP,Cryan, JF (2013) 'Semagacestat, a gamma-secretase inhibitor, activates the growth hormone secretagogue (GHS-R1a) receptor'. Journal of Pharmacy and Pharmacology, 65 :528-538 [DOI] [Details]
(2013)'Impact of early-life stress, on group III mGlu receptor levels in the rat hippocampus: Effects of ketamine, electroconvulsive shock therapy and fluoxetine treatment'
O'Connor, RM,Pusceddu, MM,Dinan, TG,Cryan, JF (2013) 'Impact of early-life stress, on group III mGlu receptor levels in the rat hippocampus: Effects of ketamine, electroconvulsive shock therapy and fluoxetine treatment'. Neuropharmacology, 66 :236-241 [DOI] [Details]
(2013)'Hippocampal group III mGlu receptor mRNA levels are not altered in specific mouse models of stress, depression and antidepressant action'
O'Connor, RM,Pusceddu, MM,O'Leary, OF,Savignac, HM,Bravo, JA,El Yacoubi, M,Vaugeois, JM,Dinan, TG,Cryan, JF (2013) 'Hippocampal group III mGlu receptor mRNA levels are not altered in specific mouse models of stress, depression and antidepressant action'. Pharmacology Biochemistry and Behavior, 103 :561-567 [DOI] [Details]
(2013)'Self-assembling Modified beta-Cyclodextrin Nanoparticles as Neuronal siRNA Delivery Vectors: Focus on Huntington's Disease'
Godinho, BMDC,Ogier, JR,Darcy, R,Driscoll, CM,Cryan, JF (2013) 'Self-assembling Modified beta-Cyclodextrin Nanoparticles as Neuronal siRNA Delivery Vectors: Focus on Huntington's Disease'. Molecular Pharmaceutics, 10 :640-649 [DOI] [Details]
(2013)'Promiscuous Dimerization of the Growth Hormone Secretagogue Receptor (GHS-R1a) Attenuates Ghrelin-mediated Signaling'
Schellekens, H,van Oeffelen, WEPA,Dinan, TG,Cryan, JF (2013) 'Promiscuous Dimerization of the Growth Hormone Secretagogue Receptor (GHS-R1a) Attenuates Ghrelin-mediated Signaling'. The Journal of Biological Chemistry, 288 :181-191 [DOI] [Details]
(2012)'Characterisation of cationic amphiphilic cyclodextrins for neuronal delivery of siRNA: Effect of reversing primary and secondary face modifications'
O'Mahony, AM,Doyle, D,Darcy, R,Cryan, JF,O'Driscoll, CM (2012) 'Characterisation of cationic amphiphilic cyclodextrins for neuronal delivery of siRNA: Effect of reversing primary and secondary face modifications'. European Journal of Pharmaceutical Sciences, 47 :896-903 [DOI] [Details]
(2012)'Communication between gastrointestinal bacteria and the nervous system'
Bravo, JA,Julio-Pieper, M,Forsythe, P,Kunze, W,Dinan, TG,Bienenstock, J,Cryan, JF (2012) 'Communication between gastrointestinal bacteria and the nervous system'. Current Opinion In Pharmacology, 12 :667-672 [DOI] [Details]
(2013)'P-glycoprotein Inhibition Increases the Brain Distribution and Antidepressant-Like Activity of Escitalopram in Rodents'
O'Brien FE, O'Connor RM, Clarke G, Dinan TG, Griffin BT, Cryan JF (2013) 'P-glycoprotein Inhibition Increases the Brain Distribution and Antidepressant-Like Activity of Escitalopram in Rodents'. Neuropsychopharmacology, [DOI] [Details]
(2014)'Microbiota is essential for social development in the mouse'
Desbonnet, L; Clarke, G; Shanahan, F; Dinan, TG; Cryan, JF (2014) 'Microbiota is essential for social development in the mouse'. Molecular Psychiatry, [DOI] [Details]
(2013)'Human P-glycoprotein Differentially Affects Antidepressant Drug Transport: Relevance to Blood-Brain Barrier Permeability'
O'Brien FE; Clarke G; Dinan TG; Griffin BT; Cryan JF (2013) 'Human P-glycoprotein Differentially Affects Antidepressant Drug Transport: Relevance to Blood-Brain Barrier Permeability'. International Journal of Neurosychopharmacology, [Details]
(2013)'Alterations in prefrontal cortical serotonin and antidepressant-like behavior in a novel C3H/HeJxDBA/2J recombinant inbred mouse strain'
Browne CA; Clarke G; Hanke J; Dinan TG; Schwegler H; Yilmazer-Hanke DM; Cryan JF (2013) 'Alterations in prefrontal cortical serotonin and antidepressant-like behavior in a novel C3H/HeJxDBA/2J recombinant inbred mouse strain'. Behavioral Brain Research, [Details]
(2013)'Self-assembling Modified Beta-Cyclodextrin Nanoparticles as Neuronal siRNA Delivery Vectors: Focus on Huntington's Disease. Molecular Pharmaceutics'
Godinho BMDC, Ogier JR, Darcy R, O'Driscoll CM, Cryan JF (2013) 'Self-assembling Modified Beta-Cyclodextrin Nanoparticles as Neuronal siRNA Delivery Vectors: Focus on Huntington's Disease. Molecular Pharmaceutics'. Molecular Pharmaceutics, 10 :640-649 [DOI] [Details]
(2014)'A review of ketamine in affective disorders: Current evidence of clinical efficacy, limitations of use and pre-clinical evidence on proposed mechanisms of action'
Naughton M, Clarke G, O'Leary OF, Cryan JF, Dinan TG (2014) 'A review of ketamine in affective disorders: Current evidence of clinical efficacy, limitations of use and pre-clinical evidence on proposed mechanisms of action'. Journal of Affective Disorders, 156 :24-35 [Details]
(2013)'Effects of the Intestinal Microbiota on Behavior and Brain Biochemistry'
Barrett, E.,Dinan, T. G.,Cryan, J. F.,Quigley, E. M. M.,Shanahan, F.,O'Toole, P. W.,Fitzgerald, G. F.,Stanton, C.,Ross, R. P. (2013) 'Effects of the Intestinal Microbiota on Behavior and Brain Biochemistry'. Probiotic Bacteria and Their Effect on Human Health and Well-Being, 107 :56-6356   [Details]
(2014)'Activation but not Blockade of GABAB Receptors During Early-life Alters Anxiety in Adulthood in BALB/c mice'
Sweeney F., O'Leary O.F., Cryan J.F. (2014) 'Activation but not Blockade of GABAB Receptors During Early-life Alters Anxiety in Adulthood in BALB/c mice'. Neuropharmacology, 81 :303-310 [Details]
(2013)'GABAB receptor ligands do not modify conditioned fear responses in BALB/c mice'
Sweeney F.F., O'Leary O.F., Cryan J.F. (2013) 'GABAB receptor ligands do not modify conditioned fear responses in BALB/c mice'. Behavioural Brain Research, 256 :151-156 [DOI] [Details]
(2013)'Human P-glycoprotein differentially affects antidepressant drug transport: relevance to blood-brain barrier permeability'
O'Brien FE, Clarke G, Dinan TG, Cryan JF, Griffin BT (2013) 'Human P-glycoprotein differentially affects antidepressant drug transport: relevance to blood-brain barrier permeability'. International Journal of Neuropsychopharmacology, :1-14 [DOI] [Details]
(2013)'Cationic and PEGylated amphiphilic Cyclodextrins: Co-formulation opportunities for neuronal siRNA delivery. PLoS ONE'
O'Mahony AM, Ogier J, Darcy R, Cryan JF, O'Driscoll CM (2013) 'Cationic and PEGylated amphiphilic Cyclodextrins: Co-formulation opportunities for neuronal siRNA delivery. PLoS ONE'. Plos One, 8 (6) [DOI] [Details]
(2013)'The microbiome-gut-brain axis during early life regulates the hippocampal serotonergic system in a sex-dependent manner'
Clarke, G.,Grenham, S.,Scully, P.,Fitzgerald, P.,Moloney, R. D.,Shanahan, F.,Dinan, T. G.,Cryan, J. F. (2013) 'The microbiome-gut-brain axis during early life regulates the hippocampal serotonergic system in a sex-dependent manner'. Molecular Psychiatry, 18 (66):666-673   [Details]
(2013)'A Prospective Assessment of Cognitive Performance in Irritable Bowel Syndrome Reveals Persistent Visuospatial Memory Deficits'
Kennedy, P. J.,Clarke, G.,Allen, A. P.,O'Neill, A.,Groeger, J. A.,Quigley, E. M.,Shanahan, F.,Cryan, J. F.,Dinan, T. G. (2013) 'A Prospective Assessment of Cognitive Performance in Irritable Bowel Syndrome Reveals Persistent Visuospatial Memory Deficits'. Gastroenterology, 144 (55)   [Details]
(2013)'Differential nanotoxicological and neuroinflammatory liabilities of non-viral vectors for RNA interference in the central nervous system'
Godinho BMDC., McCarthy DJ., Torres-Fuentes C., Beltrán CJ., McCarthy J., Quinlan A., Ogier JR., Darcy R., O’Driscoll CM.., Cryan JF. (2013) 'Differential nanotoxicological and neuroinflammatory liabilities of non-viral vectors for RNA interference in the central nervous system'. Biomaterials, [Details]
(2013)'Drugs, Genes and the Blues: Pharmacogenetics of the Antidepressant Response from Mouse to Man'
O’Leary O.F., O’Brien F.E., O’Connor R.M., Cryan J.F. (2013) 'Drugs, Genes and the Blues: Pharmacogenetics of the Antidepressant Response from Mouse to Man'. Pharmacology Biochemistry and Behavior, (123):55-76 [Details]
(2013)'Differential visceral nociceptive, behavioural and neurochemical responses to an immune challenge in the stress-sensitive Wistar Kyoto rat strain'
O' Mahony SM, Clarke G, McKernan DP, Bravo JA, Dinan TG, Cryan JF. (2013) 'Differential visceral nociceptive, behavioural and neurochemical responses to an immune challenge in the stress-sensitive Wistar Kyoto rat strain'. European Journal of Pharmacology, 15 (253):310-317 [DOI] [Details]
(2012)'Bifidobacterium breve with alpha-Linolenic Acid and Linoleic Acid Alters Fatty Acid Metabolism in the Maternal Separation Model of Irritable Bowel Syndrome'
Barrett, E.,Fitzgerald, P.,Dinan, T. G.,Cryan, J. F.,Ross, R. P.,Quigley, E. M.,Shanahan, F.,Kiely, B.,Fitzgerald, G. F.,O'Toole, P. W.,Stanton, C. (2012) 'Bifidobacterium breve with alpha-Linolenic Acid and Linoleic Acid Alters Fatty Acid Metabolism in the Maternal Separation Model of Irritable Bowel Syndrome'. PLoS One, 7 (1111)   [Details]
(2012)'The microbiome-gut-brain axis as a regulator of serotonergic neurotransmission and behaviour'
Clarke, G.,Grenham, S.,Scully, P.,Fitzgerald, P.,Moloney, R.,Shanahan, F.,Dinan, T.,Cryan, J. (2012) 'The microbiome-gut-brain axis as a regulator of serotonergic neurotransmission and behaviour'. Neurogastroenterology and Motility, 24 :149-149149   [Details]
(2012)'An Assessment of Cognitive Function in Irritable Bowel Syndrome (IBS): Are Deficits in Visuo-Spatial Memory Stress-Related and Mediated by Tryptophan Metabolism Along the Kynurenine Pathway?'
Kennedy, P. J.,Clarke, G.,O'Neill, A.,Groeger, J. A.,Quigley, E. M.,Shanahan, F.,Cryan, J. F.,Dinan, T. G. (2012) 'An Assessment of Cognitive Function in Irritable Bowel Syndrome (IBS): Are Deficits in Visuo-Spatial Memory Stress-Related and Mediated by Tryptophan Metabolism Along the Kynurenine Pathway?'. Gastroenterology, 142 (55)   [Details]
(2012)'An evaluation of neuropsychological performance in Irritable Bowel Syndrome (IBS): Relationship between altered visuo-spatial memory function, salivary cortisol levels and tryptophan metabolism along the kynurenine pathway'
Kennedy, P.,Clarke, G.,O'Neill, A.,O'Mahony, C.,Groeger, J. A.,Quigley, E. M.,Shanahan, F.,Cryan, J. F.,Dinan, T. G. (2012) 'An evaluation of neuropsychological performance in Irritable Bowel Syndrome (IBS): Relationship between altered visuo-spatial memory function, salivary cortisol levels and tryptophan metabolism along the kynurenine pathway'. Neurogastroenterology and Motility, 24 :175-175175   [Details]
(2012)'Regulation of Serotonergic Neurotransmission and Behaviour by the Brain-Gut-Microbiome Axis'
Clarke, G.,Grenham, S.,Fitzgerald, P.,Moloney, R. D.,Shanahan, F.,Dinan, T. G.,Cryan, J. F. (2012) 'Regulation of Serotonergic Neurotransmission and Behaviour by the Brain-Gut-Microbiome Axis'. Gastroenterology, 142 (55)   [Details]
(2008)'Tryptophan catabolism in irritable bowel syndrome: Relationship to cytokines, severity and psychiatric co-morbidity'
Fitzgerald, P.,Clarke, G.,Scully, P.,Cryan, J. F.,Shanahan, F.,Quigley, E. M.,Cassidy, E.,Dinan, T. G. (2008) 'Tryptophan catabolism in irritable bowel syndrome: Relationship to cytokines, severity and psychiatric co-morbidity'. Gastroenterology, 134 (44)   [Details]
(2008)'Tryptophan catabolism in females with irritable bowel syndrome: relationship to interferon-gamma, severity of symptoms and psychiatric co-morbidity'
Fitzgerald, P.,Eugene, M. C.,Clarke, G.,Scully, P.,Barry, S.,Eamonn, M. M. Q.,Shanahan, F.,Cryan, J.,Timothy, G. D. (2008) 'Tryptophan catabolism in females with irritable bowel syndrome: relationship to interferon-gamma, severity of symptoms and psychiatric co-morbidity'. Neurogastroenterology and Motility, 20 (1212):1291-12971291   [Details]
(2008)'Enhanced Cholinergic-Mediated Increase in the Pro-Inflammatory Cytokine IL-6 in Irritable Bowel Syndrome: Role of Muscarinic Receptors'
Dinan, T. G.,Clarke, G.,Quigley, E. M. M.,Scott, L. V.,Shanahan, F.,Cryan, J.,Cooney, J.,Keeling, P. W. N. (2008) 'Enhanced Cholinergic-Mediated Increase in the Pro-Inflammatory Cytokine IL-6 in Irritable Bowel Syndrome: Role of Muscarinic Receptors'. 103 (1010):2570-25762570   [Details]
(2013)'Crosstalk between interleukin-6 and corticotropin-releasing factor modulate submucosal plexus activity and colonic secretion'
O'Malley, D,Cryan, JF,Dinan, TG (2013) 'Crosstalk between interleukin-6 and corticotropin-releasing factor modulate submucosal plexus activity and colonic secretion'. Brain Behav Immun, 30 :115-124 [DOI] [Details]
(2013)'Antipsychotics and the gut microbiome: olanzapine-induced metabolic dysfunction is attenuated by antibiotic administration in the rat'
Davey, KJ,Cotter, PD,O'Sullivan, O,Crispie, F,Dinan, TG,Cryan, JF,O'Mahony, SM (2013) 'Antipsychotics and the gut microbiome: olanzapine-induced metabolic dysfunction is attenuated by antibiotic administration in the rat'. Translational Psychiatry, 3 [DOI] [Details]
(2014)'Differential nanotoxicological and neuroinflammatory liabilities of non-viral vectors for RNA interference in the central nervous system'
Godinho, BMDC,McCarthy, DJ,Torres-Fuentes, C,Beltran, CJ,McCarthy, J,Quinlan, A,Ogier, JR,Darcy, R,O'Driscoll, CM,Cryan, JF (2014) 'Differential nanotoxicological and neuroinflammatory liabilities of non-viral vectors for RNA interference in the central nervous system'. Biomaterials, 35 :489-499 [DOI] [Details]
(2011)'Transient inactivation of the infralimbic cortex induces antidepressant-like effects in the rat'
Slattery, DA,Neumann, ID,Cryan, JF (2011) 'Transient inactivation of the infralimbic cortex induces antidepressant-like effects in the rat'. Journal of psychopharmacology (Oxford, England), 25 :1295-1303 [DOI] [Details]
(2013)'Adult siRNA-induced knockdown of mGlu(7) receptors reduces anxiety in the mouse'
O'Connor, RM,Thakker, DR,Schmutz, M,van der Putten, H,Hoyer, D,Flor, PJ,Cryan, JF (2013) 'Adult siRNA-induced knockdown of mGlu(7) receptors reduces anxiety in the mouse'. Neuropharmacology, 72 :66-73 [DOI] [Details]
(2013)'Human P-glycoprotein differentially affects antidepressant drug transport: relevance to blood-brain barrier permeability'
O'Brien, FE,Clarke, G,Dinan, TG,Cryan, JF,Griffin, BT (2013) 'Human P-glycoprotein differentially affects antidepressant drug transport: relevance to blood-brain barrier permeability'. International Journal of Neuropsychopharmacology, 16 :2259-2272 [DOI] [Details]
(2014)'The P-glycoprotein inhibitor cyclosporin A differentially influences behavioural and neurochemical responses to the antidepressant escitalopram'
O'Brien, F.E., O'Connor, R.M., Clarke, G., Donovan, M.D., Dinan, T.G., Griffin, B.T., Cryan, J.F. (2014) 'The P-glycoprotein inhibitor cyclosporin A differentially influences behavioural and neurochemical responses to the antidepressant escitalopram'. Behavioral Brain Research, 15 (261):17-25 [DOI] [Details]
(2015)'The effect of organic anion transporter 3 inhibitor probenecid on bumetanide levels in the brain: an integrated in vivo microdialysis study in the rat'
Donovan MD, O'Brien FE, Boylan GB, Cryan JF, Griffin BT (2015) 'The effect of organic anion transporter 3 inhibitor probenecid on bumetanide levels in the brain: an integrated in vivo microdialysis study in the rat'. The Journal of pharmacy and pharmacology, [DOI] [Details]
(2014)'Microbiota and neurodevelopmental windows: implications for brain disorders'
Borre YE, O'Keeffe GW, Clarke G, Stanton C, Dinan TG, Cryan JF. (2014) 'Microbiota and neurodevelopmental windows: implications for brain disorders'. Trends In Molecular Medicine, 20 (9):509-518 [Details]
(2015)'Delivering a Disease-Modifying Treatment for Huntington's Disease'
Godinho BMDC, Malhotra M, O’Driscoll CM, Cryan JF. (2015) 'Delivering a Disease-Modifying Treatment for Huntington's Disease'. Drug Discovery Today, 20 (1) [DOI] [Details]
(2013)'Non-Viral Nanosystems for Gene and siRNA delivery to the Central Nervous System: Formulating the Solution'
O’Mahony AM,. Godinho BMDC, Cryan JF and O’Driscoll CM. (2013) 'Non-Viral Nanosystems for Gene and siRNA delivery to the Central Nervous System: Formulating the Solution'. Journal of Pharmaceutical Sciences, 102 :4369-4384 [Details]
(2014)'Bacterial neuroactive compounds produced by psychobiotics'
Wall, R.,Cryan, J. F.,Ross, R. P.,Fitzgerald, G. F.,Dinan, T. G.,Stanton, C. (2014) 'Bacterial neuroactive compounds produced by psychobiotics'. Adv Exp Med Biol, 817 :221-39   [Details]
(2014)'Biological and psychological markers of stress in humans: Focus on the Trier Social Stress Test'
Allen, A.P., Kennedy, P.J., Cryan, J.F., Dinan, T.G. & Clarke G. (2014) 'Biological and psychological markers of stress in humans: Focus on the Trier Social Stress Test'. Neuroscience & Biobehavioral Reviews, 38 :94-124 [Details]
(2014)'Priming for health: gut microbiota acquired in early life regulates physiology, brain and behaviour'
Clarke, G.,O'Mahony, S. M.,Dinan, T. G.,Cryan, J. F. (2014) 'Priming for health: gut microbiota acquired in early life regulates physiology, brain and behaviour'. Acta Paediatracta Paediatr, 103 (88):812-9   [Details]
(2014)'Immune modulation of the brain-gut-microbe axis'
El Aidy, S.,Dinan, T. G.,Cryan, J. F. (2014) 'Immune modulation of the brain-gut-microbe axis'. Front Microbiol, 5   [Details]
(2014)'Selective influence of host microbiota on cAMP-mediated ion transport in mouse colon'
Lomasney KW, Houston A, Shanahan F, Dinan TG, Cryan JF and Hyland NP. (2014) 'Selective influence of host microbiota on cAMP-mediated ion transport in mouse colon'. Neurogastroenterol & Motility, 26 (6):887-890 [Details]
(2014)'DIFFERENTIAL ACTIVATION OF THE PREFRONTAL CORTEX AND AMYGDALA FOLLOWING PSYCHOLOGICAL STRESS AND COLORECTAL DISTENSION IN THE MATERNALLY SEPARATED RAT'
Felice, VD,Gibney, SM,Gosselin, RD,Dinan, TG,O'Mahony, SM,Cryan, JF (2014) 'DIFFERENTIAL ACTIVATION OF THE PREFRONTAL CORTEX AND AMYGDALA FOLLOWING PSYCHOLOGICAL STRESS AND COLORECTAL DISTENSION IN THE MATERNALLY SEPARATED RAT'. Neuroscience, 267 :252-262 [DOI] [Details]
(2014)'Medical Student Perceptions of Radiology use in Anatomy Teaching'
Murphy KP, Crush L, O'Malley E, Daly FE, O'Tuathaigh CMP, Maher MM, Cryan JF, O'Connor OJ (2014) 'Medical Student Perceptions of Radiology use in Anatomy Teaching'. Anatomical Sciences Education, [Details]
(2014)'A Ventral View on Antidepressant Action: Roles for Adult Hippocampal Neurogenesis along the Dorso-ventral Axis'
O'Leary OF, Cryan JF (2014) 'A Ventral View on Antidepressant Action: Roles for Adult Hippocampal Neurogenesis along the Dorso-ventral Axis'. Trends In Pharmacological Sciences, 35 :675-687 [DOI] [Details]
(2014)'A natural solution for obesity: Bioactives for the prevention and treatment of weight gain. A review'
Torres-Fuentes, C.,Schellekens, H.,Dinan, T. G.,Cryan, J. F. (2014) 'A natural solution for obesity: Bioactives for the prevention and treatment of weight gain. A review'. Nutr Neurosci,   [Details]
(2014)'Early-life stress induces persistent alterations in 5-HT1A receptor and serotonin transporter mRNA expression in the adult rat brain'
Bravo, J. A.,Dinan, T. G.,Cryan, J. F. (2014) 'Early-life stress induces persistent alterations in 5-HT1A receptor and serotonin transporter mRNA expression in the adult rat brain'. Front Mol Neurosci, 7   [Details]
(2014)'Differential activation of the prefrontal cortex and amygdala following psychological stress and colorectal distension in the maternally separated rat'
Felice, V. D.,Gibney, S. M.,Gosselin, R. D.,Dinan, T. G.,O'Mahony, S. M.,Cryan, J. F. (2014) 'Differential activation of the prefrontal cortex and amygdala following psychological stress and colorectal distension in the maternally separated rat'. Neuroscienceneuroscience, 267 :252-62   [Details]
(2014)'Differential visceral pain sensitivity and colonic morphology in four common laboratory rat strains'
O'Malley, D.,Julio-Pieper, M.,O'Mahony, S. M.,Dinan, T. G.,Cryan, J. F. (2014) 'Differential visceral pain sensitivity and colonic morphology in four common laboratory rat strains'. Exp Physiol, 99 (22):359-67   [Details]
(2014)'Disturbance of the Gut Microbiota in Early-Life Selectively Affects Visceral Pain in Adulthood without Impacting Cognitive or Anxiety-Related Behaviors in Male Rats'
O'mahony, S. M.,Felice, V. D.,Nally, K.,Savignac, H. M.,Claesson, M. J.,Scully, P.,Woznicki, J.,Hyland, N. P.,Shanahan, F.,Quigley, E. M.,Marchesi, J. R.,O'Toole, P. W.,Dinan, T. G.,Cryan, J. F. (2014) 'Disturbance of the Gut Microbiota in Early-Life Selectively Affects Visceral Pain in Adulthood without Impacting Cognitive or Anxiety-Related Behaviors in Male Rats'. Neuroscience, 277 :885-901   [Details]
(2014)'The impact of microbiota on brain and behavior: mechanisms & therapeutic potential'
Borre, Y. E.,Moloney, R. D.,Clarke, G.,Dinan, T. G.,Cryan, J. F. (2014) 'The impact of microbiota on brain and behavior: mechanisms & therapeutic potential'. Adv Exp Med Biol, 817 :373-403   [Details]
(2014)'The mouse cyclophosphamide model of bladder pain syndrome: tissue characterization, immune profiling, and relationship to metabotropic glutamate receptors'
Golubeva AV, Zhdanov AV, Mallel G, Dinan TG and Cryan JF. (2014) 'The mouse cyclophosphamide model of bladder pain syndrome: tissue characterization, immune profiling, and relationship to metabotropic glutamate receptors'. Physiol Repphysiol Rep, 2 (33)   [Details]
(2014)'Biological and psychological markers of stress in humans: focus on the Trier Social Stress Test'
Allen, A. P.,Kennedy, P. J.,Cryan, J. F.,Dinan, T. G.,Clarke, G. (2014) 'Biological and psychological markers of stress in humans: focus on the Trier Social Stress Test'. Neurosci Biobehav Rev, 38 :94-124   [Details]
(2014)'Acute tryptophan depletion reduces kynurenine levels: Implications for treatment of visuospatial memory performance in irritable bowel syndrome'
Kennedy, P.J., Allen, A.P., O’Neill, A., Quigley, E.M.M., Cryan, J.F., Dinan, T.G., Clarke G. (2014) 'Acute tryptophan depletion reduces kynurenine levels: Implications for treatment of visuospatial memory performance in irritable bowel syndrome'. Psychopharmacology, [DOI] [Details]
(2014)'Soluble mediators in plasma from irritable bowel syndrome patients excite rat submucosal neurons'
O'Malley D, Buckley MM, McKernan DP, Quigley EM, Cryan JF, Dinan TG (2014) 'Soluble mediators in plasma from irritable bowel syndrome patients excite rat submucosal neurons'. Brain Behav Immun, [DOI] [Details]
(2014)'Faster, better, stronger: Towards new antidepressant therapeutic strategies'
O'Leary OF, Dinan TG, Cryan JF (2014) 'Faster, better, stronger: Towards new antidepressant therapeutic strategies'. European journal of pharmacology, [DOI] [Details]
(2014)'Strain differences in stress-induced changes in central CRF1 receptor expression'
O'Malley, D,Julio-Pieper, M,Dinan, TG,Cryan, JF (2014) 'Strain differences in stress-induced changes in central CRF1 receptor expression'. Neuroscience letters, 561 :192-197 [DOI] [Details]
(2014)'The Ups and Downs of Modelling Mood Disorders in Rodents'
Slattery, DA,Cryan, JF (2014) 'The Ups and Downs of Modelling Mood Disorders in Rodents'. Ilar Journal, 55 :297-309 [DOI] [Details]
(2014)'Role of adult hippocampal neurogenesis in stress resilience'
Levone BR, Cryan JF, O'Leary OF (2014) 'Role of adult hippocampal neurogenesis in stress resilience'. Neurobiology of Stress, 1 :147-155 [DOI] [Details]
(2014)'Faster, better, stronger: Towards new antidepressant therapeutic strategies'
O'Leary, O. F.,Dinan, T. G.,Cryan, J. F. (2014) 'Faster, better, stronger: Towards new antidepressant therapeutic strategies'. Eur J Pharmacol,   [Details]
(2014)'Long-lasting glutamatergic modulation induced by neonatal GABA enhancement in mice'
Melamed, O.,Levav-Rabkin, T.,Zukerman, C.,Clarke, G.,Cryan, J. F.,Dinan, T. G.,Grossman, Y.,Golan, H. M. (2014) 'Long-lasting glutamatergic modulation induced by neonatal GABA enhancement in mice'. Neuropharmacology, 79 :616-25   [Details]
(2014)'Microbial genes, brain & behaviour - epigenetic regulation of the gut-brain axis'
Stilling, R. M.,Dinan, T. G.,Cryan, J. F. (2014) 'Microbial genes, brain & behaviour - epigenetic regulation of the gut-brain axis'. Genes Brain Behav, 13 (11):69-86   [Details]
(2014)'The microbiome: stress, health and disease'
Moloney, R. D.,Desbonnet, L.,Clarke, G.,Dinan, T. G.,Cryan, J. F. (2014) 'The microbiome: stress, health and disease'. Mamm Genome, 25 (1-21-2):49-74   [Details]
(2014)'Gut microbiota, the pharmabiotics they produce and host health'
Patterson, E.,Cryan, J. F.,Fitzgerald, G. F.,Ross, R. P.,Dinan, T. G.,Stanton, C. (2014) 'Gut microbiota, the pharmabiotics they produce and host health'. Proc Nutr Soc, :1-13   [Details]
(2014)'Serotonin, tryptophan metabolism and the brain-gut-microbiome axis'
O'Mahony, S. M.,Clarke, G.,Borre, Y. E.,Dinan, T. G.,Cryan, J. F. (2014) 'Serotonin, tryptophan metabolism and the brain-gut-microbiome axis'. Behav Brain Resbehav Brain Res,   [Details]
(2014)'Devil's Claw to suppress appetite--ghrelin receptor modulation potential of a Harpagophytum procumbens root extract'
Torres-Fuentes, C.,Theeuwes, W. F.,McMullen, M. K.,McMullen, A. K.,Dinan, T. G.,Cryan, J. F.,Schellekens, H. (2014) 'Devil's Claw to suppress appetite--ghrelin receptor modulation potential of a Harpagophytum procumbens root extract'. PLoS One, 9 (77)   [Details]
(2014)'Converging effects of a Bifidobacterium and Lactobacillus probiotic strain on mouse intestinal physiology'
Lomasney, KW,Cryan, JF,Hyland, NP (2014) 'Converging effects of a Bifidobacterium and Lactobacillus probiotic strain on mouse intestinal physiology'. American Journal Of Physiology-Gastrointestinal And Liver Physiology, 307 :241-247 [DOI] [Details]
(2014)'A sustained hypothalamic-pituitary-adrenal axis response to acute psychosocial stress in irritable bowel syndrome'
Kennedy, P. J.,Cryan, J. F.,Quigley, E. M.,Dinan, T. G.,Clarke, G. (2014) 'A sustained hypothalamic-pituitary-adrenal axis response to acute psychosocial stress in irritable bowel syndrome'. Psychol Med, 44 (1414):3123-34   [Details]
(2014)'Microbiota and neurodevelopmental windows: implications for brain disorders'
Borre, Y. E.,O'Keeffe, G. W.,Clarke, G.,Stanton, C.,Dinan, T. G.,Cryan, J. F. (2014) 'Microbiota and neurodevelopmental windows: implications for brain disorders'. Trends In Molecular Medicine, 20 (99):509-518   [DOI] [Details]
(2014)'Minireview: gut microbiota: the neglected endocrine organ'
Clarke, G.,Stilling, R. M.,Kennedy, P. J.,Stanton, C.,Cryan, J. F.,Dinan, T. G. (2014) 'Minireview: gut microbiota: the neglected endocrine organ'. Mol Endocrinol, 28 (88):1221-38   [Details]
(2014)'Strain differences in stress-induced changes in central CRF1 receptor expression'
O'Malley, D.,Julio-Piepera, M.,Dinan, T. G.,Cryan, J. F. (2014) 'Strain differences in stress-induced changes in central CRF1 receptor expression'. Neurosci Lett, 561 :192-7   [Details]
(2014)'Faster, Better, Stronger: Towards New Antidepressant Therapeutic Strategies'
O'leary O.F, Dinan T.G, Cryan J.F. (2014) 'Faster, Better, Stronger: Towards New Antidepressant Therapeutic Strategies'. European Journal of Pharmacology, 123 :55-76 [DOI] [Details]
(2014)'A prospective study of C-reactive protein as a state marker in Cardiac Syndrome X'
Dollard, J.,Kearney, P.,Clarke, G.,Moloney, G.,Cryan, J. F.,Dinan, T. G. (2014) 'A prospective study of C-reactive protein as a state marker in Cardiac Syndrome X'. Brain Behav Immun,   [Details]
(2014)'Toll-like receptor 4 regulates chronic stress-induced visceral pain in mice'
Tramullas, M.,Finger, B. C.,Moloney, R. D.,Golubeva, A. V.,Moloney, G.,Dinan, T. G.,Cryan, J. F. (2014) 'Toll-like receptor 4 regulates chronic stress-induced visceral pain in mice'. Biol Psychiatry, 76 (44):340-8   [Details]
(2014)'Gut microbiota, the pharmabiotics they produce and host health'
Patterson E, Cryan JF, Fitzgerald GF, Ross RP, Dinan TG, Stanton C (2014) 'Gut microbiota, the pharmabiotics they produce and host health'. The Proceedings of The Nutrition Society, :1-13 [DOI] [Details]
(2014)'Disturbance of the gut microbiota in early-life selectively affects visceral pain in adulthood without impacting cognitive or anxiety-related behaviors in male rats'
O'Mahony SM, Felice VD, Nally K, Savignac HM, Claesson MJ, Scully P, Woznicki J, Hyland NP, Shanahan F, Quigley EM, Marchesi JR, O'Toole PW, Dinan TG, Cryan JF (2014) 'Disturbance of the gut microbiota in early-life selectively affects visceral pain in adulthood without impacting cognitive or anxiety-related behaviors in male rats'. Neuroscience, 277C :885-901 [DOI] [Details]
(2014)'Gut microbiota modulation and implications for host health: Dietary strategies to influence the gut-brain axis'
Marques, TM,Cryan, JF,Shanahan, F,Fitzgerald, GF,Ross, RP,Dinan, TG,Stanton, C (2014) 'Gut microbiota modulation and implications for host health: Dietary strategies to influence the gut-brain axis'. Innovative Food Science & Emerging Technologies, 22 :239-247 [DOI] [Details]
(2014)'PEGylated cyclodextrins as Novel siRNA nanosystems: correlations between polyethylene glycol length and nanoparticle stability'
Godinho BMDC, Ogier JR, Quinlan A, Darcy R, Griffin BT, Cryan JF, O’Driscoll CM. (2014) 'PEGylated cyclodextrins as Novel siRNA nanosystems: correlations between polyethylene glycol length and nanoparticle stability'. International Journal of Pharmaceutics, 473 :105-112 [Details]
(2014)'A sustained hypothalamic-pituitary-adrenal axis response to acute psychosocial stress in irritable bowel syndrome'
Kennedy, PJ,Cryan, JF,Quigley, EMM,Dinan, TG,Clarke, G (2014) 'A sustained hypothalamic-pituitary-adrenal axis response to acute psychosocial stress in irritable bowel syndrome'. Psychological medicine, 44 :3123-3134 [DOI] [Details]
(2014)'Cognitive performance in irritable bowel syndrome: evidence of a stress-related impairment in visuospatial memory'
Kennedy, P. J.,Clarke, G.,O'Neill, A.,Groeger, J. A.,Quigley, E. M.,Shanahan, F.,Cryan, J. F.,Dinan, T. G. (2014) 'Cognitive performance in irritable bowel syndrome: evidence of a stress-related impairment in visuospatial memory'. Psychol Med, 44 (77):1553-66   [Details]
(2014)'Blocking Metabotropic Glutamate Receptor Subtype 7 ( mGlu7) via the Venus Flytrap Domain ( VFTD) Inhibits Amygdala Plasticity, Stress, and Anxiety-related Behavior'
Gee, CE,Peterlik, D,Neuhauser, C,Bouhelal, R,Kaupmann, K,Laue, G,Uschold-Schmidt, N,Feuerbach, D,Zimmermann, K,Ofner, S,Cryan, JF,van der Putten, H,Fendt, M,Vranesic, I,Glatthar, R,Flor, PJ (2014) 'Blocking Metabotropic Glutamate Receptor Subtype 7 ( mGlu7) via the Venus Flytrap Domain ( VFTD) Inhibits Amygdala Plasticity, Stress, and Anxiety-related Behavior'. The Journal of Biological Chemistry, 289 :10975-10987 [DOI] [Details]
(2014)'Effect of Acute Swim Stress on Plasma Corticosterone and Brain Monoamine Levels in Bidirectionally Selected DxH Recombinant Inbred Mouse Strains Differing in Fear Recall and Extinction'
5. Browne CA, Hanke J, Rose C, Walsh I, Foley T, Clarke G, Schwegler H, Cryan JF, Yilmazer-Hanke D. (2014) 'Effect of Acute Swim Stress on Plasma Corticosterone and Brain Monoamine Levels in Bidirectionally Selected DxH Recombinant Inbred Mouse Strains Differing in Fear Recall and Extinction'. Stress (Amsterdam, Netherlands), [Details]
(2014)'PEGylated cyclodextrins as novel siRNA nanosystems: Correlations between polyethylene glycol length and nanoparticle stability'
Godinho, BMDC,Ogier, JR,Quinlan, A,Darcy, R,Griffin, BT,Cryan, JF,Driscoll, CM (2014) 'PEGylated cyclodextrins as novel siRNA nanosystems: Correlations between polyethylene glycol length and nanoparticle stability'. International Journal of Pharmaceutics, 473 :105-112 [DOI] [Details]
(2014)'Devil's Claw to suppress appetite--ghrelin receptor modulation potential of a Harpagophytum procumbens root extract'
Torres-Fuentes C, Theeuwes WF, McMullen MK, McMullen AK, Dinan TG, Cryan JF, Schellekens H (2014) 'Devil's Claw to suppress appetite--ghrelin receptor modulation potential of a Harpagophytum procumbens root extract'. Plos One, 9 (7) [DOI] [Details]
(2014)'A review of ketamine in affective disorders: current evidence of clinical efficacy, limitations of use and pre-clinical evidence on proposed mechanisms of action'
Naughton, M.,Clarke, G.,O'Leary, O. F.,Cryan, J. F.,Dinan, T. G. (2014) 'A review of ketamine in affective disorders: current evidence of clinical efficacy, limitations of use and pre-clinical evidence on proposed mechanisms of action'. J Affect Disord, 156 :24-35   [Details]
(2014)'Soluble mediators in plasma from irritable bowel syndrome patients excite rat submucosal neurons'
O'Malley, D.,Buckley, M. M.,McKernan, D. P.,Quigley, E. M.,Cryan, J. F.,Dinan, T. G. (2014) 'Soluble mediators in plasma from irritable bowel syndrome patients excite rat submucosal neurons'. Brain Behav Immun,   [Details]
(2014)'Milk protein-derived peptides induce 5-HT2C-mediated satiety,in vivo'
Schellekens, H,Nongonierma, AB,Clarke, G,van Oeffelen, WEPA,FitzGerald, RJ,Dinan, TG,Cryan, JF (2014) 'Milk protein-derived peptides induce 5-HT2C-mediated satiety,in vivo'. International Dairy Journal, 38 :55-64 [DOI] [Details]
(2014)'Medical student knowledge regarding radiology before and after a radiological anatomy module: implications for vertical integration and self-directed learning'
Murphy KP, Crush L, O'Malley E, Daly FE, O'Tuathaigh CM, O'Connor OJ, Cryan JF, Maher MM (2014) 'Medical student knowledge regarding radiology before and after a radiological anatomy module: implications for vertical integration and self-directed learning'. Insights into Imaging, [Details]
(2014)'GABAB(1) receptor subunit isoforms differentially regulate stress resilience'
O'Leary OF, Felice D, Galimberti S, Savignac HM, Bravo JA, Crowley T, El Yacoubi M, Vaugeois JM, Gassmann M, Bettler B, Dinan TG, Cryan JF. (2014) 'GABAB(1) receptor subunit isoforms differentially regulate stress resilience'. Proceedings of The National Academy of Science Usa, 111 (42):15232-15237 [Details]
(2014)'Birth by caesarean section and development of autism spectrum disorder and attention-deficit/hyperactivity disorder: a systematic review and meta-analysis'
Curran EA, O’Neill SM, Cryan JF, Kenny LC, Dinan TG, Khashan AS, et al (2014) 'Birth by caesarean section and development of autism spectrum disorder and attention-deficit/hyperactivity disorder: a systematic review and meta-analysis'. Journal of Child Psychology & Psychiatry,   [DOI] [Details]
(2014)'Differential visceral pain sensitivity and colonic morphology in four common laboratory rat strains'
O'Malley, D,Julio-Pieper, M,O'Mahony, SM,Dinan, TG,Cryan, JF (2014) 'Differential visceral pain sensitivity and colonic morphology in four common laboratory rat strains'. Experimental physiology, 99 :359-367 [DOI] [Details]
(2014)'DISTURBANCE OF THE GUT MICROBIOTA IN EARLY-LIFE SELECTIVELY AFFECTS VISCERAL PAIN IN ADULTHOOD WITHOUT IMPACTING COGNITIVE OR ANXIETY-RELATED BEHAVIORS IN MALE RATS'
O'Mahony, SM,Felice, VD,Nally, K,Savignac, HM,Claesson, MJ,Scully, P,Woznicki, J,Hyland, NP,Shanahan, F,Quigley, EM,Marchesi, JR,O'Toole, PW,Dinan, TG,Cryan, JF (2014) 'DISTURBANCE OF THE GUT MICROBIOTA IN EARLY-LIFE SELECTIVELY AFFECTS VISCERAL PAIN IN ADULTHOOD WITHOUT IMPACTING COGNITIVE OR ANXIETY-RELATED BEHAVIORS IN MALE RATS'. Neuroscience, 277 :885-901 [DOI] [Details]
(2014)'Devil's Claw to Suppress Appetite-Ghrelin Receptor Modulation Potential of a Harpagophytum procumbens Root Extract'
Torres-Fuentes, C,Theeuwes, WF,McMullen, MK,McMullen, AK,Dinan, TG,Cryan, JF,Schellekens, H (2014) 'Devil's Claw to Suppress Appetite-Ghrelin Receptor Modulation Potential of a Harpagophytum procumbens Root Extract'. Plos One, 9 [DOI] [Details]
(2014)'A natural solution for obesity: Bioactives for the prevention and treatment of weight gain. A review'
Torres-Fuentes C, Schellekens H, Dinan TG, Cryan JF (2014) 'A natural solution for obesity: Bioactives for the prevention and treatment of weight gain. A review'. Nutritional Neuroscience, [DOI] [Details]
(2013)'Milk protein hydrolysates activate 5-HT2C serotonin receptors: influence of the starting substrate and isolation of bioactive fractions'
Nongonierma, A. B.,Schellekens, H.,Dinan, T. G.,Cryan, J. F.,Fitzgerald, R. J. (2013) 'Milk protein hydrolysates activate 5-HT2C serotonin receptors: influence of the starting substrate and isolation of bioactive fractions'. Food & Function, 4 (55):728-37728   [Details]
(2013)'Whey protein isolate counteracts the effects of a high-fat diet on energy intake and hypothalamic and adipose tissue expression of energy balance-related genes'
McAllan L, Keane D, Schellekens H, Roche HM, Korpela R, Cryan JF, Nilaweera KN (2013) 'Whey protein isolate counteracts the effects of a high-fat diet on energy intake and hypothalamic and adipose tissue expression of energy balance-related genes'. The British journal of nutrition, 110 (11):2114-2126 [DOI] [Details]
(2013)'Semagacestat, a gamma-secretase inhibitor, activates the growth hormone secretagogue (GHS-R1a) receptor'
Schellekens, H.,McNamara, O.,Dinan, T. G.,McCarthy, J. V.,McGlacken, G. P.,Cryan, J. F. (2013) 'Semagacestat, a gamma-secretase inhibitor, activates the growth hormone secretagogue (GHS-R1a) receptor'. J Pharm Pharmacol, 65 (44):528-38528   [Details]
(2013)'Promiscuous dimerization of the growth hormone secretagogue receptor (GHS-R1a) attenuates ghrelin-mediated signaling'
Schellekens, H.,van Oeffelen, W. E.,Dinan, T. G.,Cryan, J. F. (2013) 'Promiscuous dimerization of the growth hormone secretagogue receptor (GHS-R1a) attenuates ghrelin-mediated signaling'. Journal of Biological Chemistry, 288 (11):181-91181   [Details]
(2013)'Milk protein hydrolysates activate 5-HT(2C) serotonin receptors: influence of the starting substrate and isolation of bioactive fractions'
Nongonierma AB, Schellekens H, Dinan TG, Cryan JF, FitzGerald RJ (2013) 'Milk protein hydrolysates activate 5-HT(2C) serotonin receptors: influence of the starting substrate and isolation of bioactive fractions'. Food & Function, 4 (5):728-737 [DOI] [Details]
(2013)'Ghrelin at the interface of obesity and reward'
Schellekens H, Dinan TG, Cryan JF (2013) 'Ghrelin at the interface of obesity and reward'. Vitamins and hormones, 91 :285-323 [DOI] [Details]
(2013)'Promiscuous dimerization of the growth hormone secretagogue receptor (GHS-R1a) attenuates ghrelin-mediated signaling'
Schellekens H, van Oeffelen WE, Dinan TG, Cryan JF (2013) 'Promiscuous dimerization of the growth hormone secretagogue receptor (GHS-R1a) attenuates ghrelin-mediated signaling'. The Journal of Biological Chemistry, 288 (1):181-191 [DOI] [Details]
(2013)'Whey protein isolate counteracts the effects of a high-fat diet on energy intake and hypothalamic and adipose tissue expression of energy balance-related genes'
McAllan, L.,Keane, D.,Schellekens, H.,Roche, H. M.,Korpela, R.,Cryan, J. F.,Nilaweera, K. N. (2013) 'Whey protein isolate counteracts the effects of a high-fat diet on energy intake and hypothalamic and adipose tissue expression of energy balance-related genes'. Br J Nutr, 110 (1111):2114-262114   [Details]
(2013)'Taking two to tango: a role for ghrelin receptor heterodimerization in stress and reward'
Schellekens H, Dinan TG, Cryan JF (2013) 'Taking two to tango: a role for ghrelin receptor heterodimerization in stress and reward'. Frontiers in neuroscience, 7 [DOI] [Details]
(2013)'Semagacestat, a ¿-secretase inhibitor, activates the growth hormone secretagogue (GHS-R1a) receptor'
Schellekens H, McNamara O, Dinan TG, McCarthy JV, McGlacken GP, Cryan JF (2013) 'Semagacestat, a ¿-secretase inhibitor, activates the growth hormone secretagogue (GHS-R1a) receptor'. The Journal of pharmacy and pharmacology, 65 (4):528-538 [DOI] [Details]
(2012)'Ghrelin signalling and obesity: at the interface of stress, mood and food reward'
Schellekens, H.,Finger, B. C.,Dinan, T. G.,Cryan, J. F. (2012) 'Ghrelin signalling and obesity: at the interface of stress, mood and food reward'. Pharmacol Ther, 135 (33):316-26316   [Details]
(2012)'Dynamic 5-HT2C receptor editing in a mouse model of obesity'
Schellekens, H.,Clarke, G.,Jeffery, I. B.,Dinan, T. G.,Cryan, J. F. (2012) 'Dynamic 5-HT2C receptor editing in a mouse model of obesity'. PLoS One, 7 (33)   [Details]
(2012)'Ghrelin signalling and obesity: at the interface of stress, mood and food reward'
Schellekens H, Finger BC, Dinan TG, Cryan JF (2012) 'Ghrelin signalling and obesity: at the interface of stress, mood and food reward'. Pharmacology & therapeutics, 135 (3):316-326 [DOI] [Details]
(2012)'Gender-dependent consequences of chronic olanzapine in the rat: effects on body weight, inflammatory, metabolic and microbiota parameters'
Davey, K. J.,O'Mahony, S. M.,Schellekens, H.,O'Sullivan, O.,Bienenstock, J.,Cotter, P. D.,Dinan, T. G.,Cryan, J. F. (2012) 'Gender-dependent consequences of chronic olanzapine in the rat: effects on body weight, inflammatory, metabolic and microbiota parameters'. Psychopharmacology (Berl), 221 (11):155-69155   [Details]
(2012)'Bifidobacterium breve with alpha-linolenic acid and linoleic acid alters fatty acid metabolism in the maternal separation model of irritable bowel syndrome'
Barrett, E.,Fitzgerald, P.,Dinan, T. G.,Cryan, J. F.,Ross, R. P.,Quigley, E. M.,Shanahan, F.,Kiely, B.,Fitzgerald, G. F.,O'Toole, P. W.,Stanton, C. (2012) 'Bifidobacterium breve with alpha-linolenic acid and linoleic acid alters fatty acid metabolism in the maternal separation model of irritable bowel syndrome'. Plos One, 7 (11) [Details]
(2011)'Is there altered sensitivity to ghrelin-receptor ligands in leptin-deficient mice?: importance of satiety state and time of day'
Finger, B. C.,Schellekens, H.,Dinan, T. G.,Cryan, J. F. (2011) 'Is there altered sensitivity to ghrelin-receptor ligands in leptin-deficient mice?: importance of satiety state and time of day'. Psychopharmacology (Berl), 216 (33):421-9421   [Details]
(2010)'IBS: An epigenetic perspective'
Dinan, T. G.,Cryan, J.,Shanahan, F.,Keeling, P. W.,Quigley, E. M. (2010) 'IBS: An epigenetic perspective'. Nat Rev Gastroenterol Hepatol, 7 (88):465-71 [Details]
(2008)'Tryptophan catabolism in females with irritable bowel syndrome: relationship to interferon-gamma, severity of symptoms and psychiatric co-morbidity'
Fitzgerald, P.,Cassidy Eugene, M.,Clarke, G.,Scully, P.,Barry, S.,Quigley Eamonn, M. M.,Shanahan, F.,Cryan, J.,Dinan Timothy, G. (2008) 'Tryptophan catabolism in females with irritable bowel syndrome: relationship to interferon-gamma, severity of symptoms and psychiatric co-morbidity'. Neurogastroenterol & Motility, 20 (12):1291-1297 [Details]
(2008)'Enhanced cholinergic-mediated increase in the pro-inflammatory cytokine IL-6 in irritable bowel syndrome: role of muscarinic receptors'
Dinan, T. G.,Clarke, G.,Quigley, E. M.,Scott, L. V.,Shanahan, F.,Cryan, J.,Cooney, J.,Keeling, P. W. (2008) 'Enhanced cholinergic-mediated increase in the pro-inflammatory cytokine IL-6 in irritable bowel syndrome: role of muscarinic receptors'. American Journal of Gastroenterology, 103 (10):2570-2576 [Details]
(2014)'Early-life stress selectively affects gastrointestinal but not behavioral responses in a genetic model of brain-gut axis dysfunction'
Hyland NP, O'Mahony SM, O'Malley D, O'Mahony CM, Dinan TG, Cryan JF. (2014) 'Early-life stress selectively affects gastrointestinal but not behavioral responses in a genetic model of brain-gut axis dysfunction'. Neurogastroenterology and Motility, [Details]
(2014)'Nanoparticles and the Blood-Brain Barrier: Advancing from In-Vitro Models towards Therapeutic Significance'
Mc Carthy DJ, Malhotra M, O’Mahony AM, Cryan JF and O’Driscoll CM. (2014) 'Nanoparticles and the Blood-Brain Barrier: Advancing from In-Vitro Models towards Therapeutic Significance'. Pharmaceutical Research, [DOI] [Details]
(2015)'Adult hippocampal neurogenesis is regulated by the microbiome'
Ogbonnaya ES, Clarke G, Shanahan F, Dinan TG, Cryan JF, O'Leary OF (2015) 'Adult hippocampal neurogenesis is regulated by the microbiome'. Biological Psychiatry, 78 (4):e7-9 [Details]
(2014)'Early-life stress selectively affects gastrointestinal but not behavioral responses in a genetic model of brain-gut axis dysfunction'
Hyland NP, O'Mahony SM, O'Malley D, O'Mahony CM, Dinan TG, Cryan JF. (2014) 'Early-life stress selectively affects gastrointestinal but not behavioral responses in a genetic model of brain-gut axis dysfunction'. Neurogastroenterol Motilneurogastroenterol Motil, [Details]

Other Journals

 YearPublication
(2014)'A sustained hypothalamic--pituitary--adrenal axis response to acute psychosocial stress in irritable bowel syndrome'
Kennedy, PJ and Cryan, JF and Quigley, EMM and Dinan, TG and Clarke, G (2014) 'A sustained hypothalamic--pituitary--adrenal axis response to acute psychosocial stress in irritable bowel syndrome' Psychological Medicine, :1-12. [Details]
(2007)'Emerging Use of Non-Viral Rna Interference In The Brain'
Cryan, JF, Thakker, DR, Hoyer, D; (2007) 'Emerging Use of Non-Viral Rna Interference In The Brain' (NA) :411-415. [Details]
(2014)'DISTURBANCE OF THE GUT MICROBIOTA IN EARLY-LIFE SELECTIVELY AFFECTS VISCERAL PAIN IN ADULTHOOD WITHOUT IMPACTING COGNITIVE OR ANXIETY-RELATED BEHAVIORS IN MALE RATS'
O'Mahony, S. M. and Felice, V. D. and Nally, K. and Savignac, H. M. and Claesson, M. J. and Scully, P. and Woznicki, J. and Hyland, N. P. and Shanahan, F. and Quigley, E. M. and Marchesi, J. R. and O'Toole, P. W. and Dinan, T. G. and Cryan, J. F. (2014) 'DISTURBANCE OF THE GUT MICROBIOTA IN EARLY-LIFE SELECTIVELY AFFECTS VISCERAL PAIN IN ADULTHOOD WITHOUT IMPACTING COGNITIVE OR ANXIETY-RELATED BEHAVIORS IN MALE RATS' Neuroscience, 277 :885-901. [DOI] [Details]
(2012)'Inhibition of P-glycoprotein enhances transport of imipramine across the blood--brain barrier: microdialysis studies in conscious freely moving rats'
O'Brien, FE and Clarke, G and Fitzgerald, P and Dinan, TG and Griffin, BT and Cryan, JF (2012) 'Inhibition of P-glycoprotein enhances transport of imipramine across the blood--brain barrier: microdialysis studies in conscious freely moving rats' British journal of pharmacology, 166 (4) :1333-1343. [Details]

Other

 YearPublication
(2007)Emerging use of non-viral RNA interference in the brain.
Cryan, JF,Thakker, DR,Hoyer, D (2007) Emerging use of non-viral RNA interference in the brain. Other [Details]
(2012)Reply to McLean et al. and Burnet: The microbiome-gut-brain axis as a pathway toward next generation psychotropics.
Cryan, JF,Bravo, JA,Dinan, TG,Forsythe, P,Bienenstock, J (2012) Reply to McLean et al. and Burnet: The microbiome-gut-brain axis as a pathway toward next generation psychotropics. Other [DOI] [Details]
(1997)The effects of paroxetine and pindolol in combination, on 8-OH-DPAT-induced hypothermia in the rat.
Cryan J.F., McGrath C., Leonard B.E. and Norman T.R.; (1997) The effects of paroxetine and pindolol in combination, on 8-OH-DPAT-induced hypothermia in the rat. Other [Details]
(1998)Combining pindolol and paroxetine in an animal model of chronic antidepressant action - Can early onset of action be detected?.
Cryan J.F., McGrath C., Leonard B.E., Burrows G.D. and Norman T.R.; (1998) Combining pindolol and paroxetine in an animal model of chronic antidepressant action - Can early onset of action be detected?. Other [Details]
(1998)Does the 5-HT1A receptor agonist flesinoxan and the serenic eltoprazine have antidepressant potential? An investigation in three rodent paradigms.
Cryan J.F., Redmond A.M., Kelly J.P. and Leonard B.E.; (1998) Does the 5-HT1A receptor agonist flesinoxan and the serenic eltoprazine have antidepressant potential? An investigation in three rodent paradigms. Other [Details]
(1998)The effects of melatonin and melatonin receptor ligands in the rat forced swim test.
Cryan J.F., McGrath C., Leonard B.E., Burrows G.D. and Norman T.R.; (1998) The effects of melatonin and melatonin receptor ligands in the rat forced swim test. Other [Details]
(1999)Reboxetine, a selective norepinephrine reuptake inhibitor, alters active behaviors in a modified rat forced swim test.
Cryan J.F. and Lucki I.; (1999) Reboxetine, a selective norepinephrine reuptake inhibitor, alters active behaviors in a modified rat forced swim test. Other [Details]
(1999)Differential modification of d-fenfluramine-induced serotonergic responses by acute sertraline and fluoxetine administration to rats.
Harkin A., Naughton M., Cryan J.F., Kelly J.P., and Leonard B.E.; (1999) Differential modification of d-fenfluramine-induced serotonergic responses by acute sertraline and fluoxetine administration to rats. Other [Details]
(2000)Postsynaptic Serotonin Receptors Involved in the Antidepressant-Like effects of fluoxetine: Evidence for a Role of 5-HT2C but not 5-HT4 receptors.
Cryan J.F. and Lucki I.; (2000) Postsynaptic Serotonin Receptors Involved in the Antidepressant-Like effects of fluoxetine: Evidence for a Role of 5-HT2C but not 5-HT4 receptors. Other [Details]
(2000)Noradrenergic lesions differentially alter the antidepressant -like effects of reboxetine.
Lucki I., Page M.E. and Cryan J.F.; (2000) Noradrenergic lesions differentially alter the antidepressant -like effects of reboxetine. Other [Details]
(2000)Localization of corticotropin-releasing factor binding sites on serotonergic processes in the raphe nucleus: effects of 5,7 dihydroxytryptamine.
Kirby L.G., Cryan J.F., Bello N., Lucki I. and Valentino R.J.; (2000) Localization of corticotropin-releasing factor binding sites on serotonergic processes in the raphe nucleus: effects of 5,7 dihydroxytryptamine. Other [Details]
(2000)The impact of noradrenergic lesions on the antidepressant-like effects of reboxetine.
Cryan J.F., Page M.E and Lucki I.; (2000) The impact of noradrenergic lesions on the antidepressant-like effects of reboxetine. Other [Details]
(2000)Antidepressant-like behavioral effects mediated by the 5-HT2C receptor.
Cryan J.F. and Lucki I.; (2000) Antidepressant-like behavioral effects mediated by the 5-HT2C receptor. Other [Details]
(2001)The antidepressant bupropion increases brain reward function: reversal of reward deficits associated with nicotine withdrawal.
Cryan J.F., Skjei K.S. and Markou A.; (2001) The antidepressant bupropion increases brain reward function: reversal of reward deficits associated with nicotine withdrawal. Other [Details]
(2001)Role of serotonin in the antidepressant-like effects of SSRIs in the tail suspension test.
O'Leary O.F., Page M.E., Hirsch B.R., Cryan J.F., Thomas S.A. and Lucki I.; (2001) Role of serotonin in the antidepressant-like effects of SSRIs in the tail suspension test. Other [Details]
(2001)Substantial reduction in corticotropin-releasing factor (CRF) binding sites in the dorsal raphe nucleus (drn) of rats administered 5,7-dihydroxytryptamine (5,7-DHT).
Kirby L.G. Cryan J.F., Page M.E., Bello N.T., Kung M-P., Kung H.F., Lucki I and Valentino R.J.; (2001) Substantial reduction in corticotropin-releasing factor (CRF) binding sites in the dorsal raphe nucleus (drn) of rats administered 5,7-dihydroxytryptamine (5,7-DHT). Other [Details]
(2001)Dopamine-B-hydroxylase deficient mice as a tool to assess the role of norepinephrine in the mechanism of action of antidepressant drugs.
Cryan J.F., Dalvi A., Lucki I. and Thomas S.A.; (2001) Dopamine-B-hydroxylase deficient mice as a tool to assess the role of norepinephrine in the mechanism of action of antidepressant drugs. Other [Details]
(2001)Reduced sensitivity to the antidepressant-like effects of SSRIs in dopamine-ƒÒ-hydroxylase deficient mice.
Cryan J.F., Hirsch B.R., Jin S-H, Lucki I. and Thomas S.A.; (2001) Reduced sensitivity to the antidepressant-like effects of SSRIs in dopamine-ƒÒ-hydroxylase deficient mice. Other [Details]
(2002)The antidepressant bupropion enhances brain reward function and reverses nicotine withdrawal in the rat.
Cryan J.F, Bruijnzeel A.W, Skjei K.S and Markou A; (2002) The antidepressant bupropion enhances brain reward function and reverses nicotine withdrawal in the rat. Other [Details]
(2002)Neurochemical and behavioral assays support an anxiolytic-like profile for 2-methyl-6-(phenylethynyl)pyridine (MPEP), a metabotropic glutamate receptor 5 (mGluR5) antagonist.
Page M.E., Szeliga P.J., Gasparini F. and Cryan J.F.; (2002) Neurochemical and behavioral assays support an anxiolytic-like profile for 2-methyl-6-(phenylethynyl)pyridine (MPEP), a metabotropic glutamate receptor 5 (mGluR5) antagonist. Other [Details]
(2002)Reduced sensitivity to the behavioral and neurochemical effects of SSRIs in norepinephrine-deficient mice.
O'Leary O.L. Cryan J.F., Page M.E., Thomas S.A. and Lucki I.; (2002) Reduced sensitivity to the behavioral and neurochemical effects of SSRIs in norepinephrine-deficient mice. Other [Details]
(2003)Antidepressant and anxiolytic-like effects in mice lacking the group III metabotropic glutamate receptor mGluR7.
Cryan J.F., Kelly P.H., Sansig G., Flor P.J. and van Der Putten H.; (2003) Antidepressant and anxiolytic-like effects in mice lacking the group III metabotropic glutamate receptor mGluR7. Other [Details]
(2003)GABAB receptors play a key role in the modulation of anxiety and depression-related behaviours: Evidence from GABAB(1) receptor deficient mice.
Cryan J.F. Mombereau C., Sansig G., van der Putten H. and Kaupmann K.; (2003) GABAB receptors play a key role in the modulation of anxiety and depression-related behaviours: Evidence from GABAB(1) receptor deficient mice. Other [Details]
(2003)Potential anxiolytic-like actions of metabotropic glutamate receptor 5 (mGluR5) antagonists revealed by neurochemical and behavioral studies.
Cryan J.F., Szeliga P.J., Gasparini F., Page M.E.; (2003) Potential anxiolytic-like actions of metabotropic glutamate receptor 5 (mGluR5) antagonists revealed by neurochemical and behavioral studies. Other [Details]
(2003)mGluR5 receptor antagonists, future anxiolytics?.
Gentsch C., Cryan J.F., Gasparini F., Vassout A., Spooren W.; (2003) mGluR5 receptor antagonists, future anxiolytics?. Other [Details]
(2003)GABAB receptors play a key role in the modulation of anxiety and depression-related behaviours.
Mombereau C., Kaupmann K., Sansig G., van der Putten H. And Cryan J.F.; (2003) GABAB receptors play a key role in the modulation of anxiety and depression-related behaviours. Other [Details]
(2003)Effects of yƒ{hydroxybutyrate in GABA-B receptor deficient mice.
Kaupmann, K., Cryan, J.F., Wellendorph, P. Mombereau, C. Sansig, G. Klebs, K., Schmutz, M., Froestl, W. van der Putten, H., Mosbacher, J., Bräuner-Osborne, H., Waldmeier, P., and Bettler, B.; (2003) Effects of yƒ{hydroxybutyrate in GABA-B receptor deficient mice. Other [Details]
(2004)Chronic antidepressants and GABAB receptor ligands counteract Handling-Stress induced downregulation of 5-HT1A Receptor mRNA In the hippocampus Of Balb/C Mice.
Mombereau C., Kuntzelmann G., Loetscher E., Cryan J.F.; (2004) Chronic antidepressants and GABAB receptor ligands counteract Handling-Stress induced downregulation of 5-HT1A Receptor mRNA In the hippocampus Of Balb/C Mice. Other [Details]
(2004)Novel pharmacological agents modulating GABAB receptor function: Potential therapeutics for nicotine dependence.
Kaupmann K., Lhuillier L., Mombereau C., Slattery D.A., Dupuis D.S., and Cryan J.F.; (2004) Novel pharmacological agents modulating GABAB receptor function: Potential therapeutics for nicotine dependence. Other [Details]
(2004)GABAB Receptors Play a Key Role in the Modulation of Anxiety and Antidepressant-Related Behaviour: Genetic And Pharmacological Evidence.
Mombereau C., Kaupmann K., Froestl W., Van Der Putten H. and Cryan, J.F.; (2004) GABAB Receptors Play a Key Role in the Modulation of Anxiety and Antidepressant-Related Behaviour: Genetic And Pharmacological Evidence. Other [Details]
(2004)Genetic dissection of GABAB receptor function in mice.
Gassmann M., Vigot R., Shaban H., Barbieri S., Brauner-Osborne H., Thi A.L., Cryan J.F., Kaupmann K. and Bettler B.; (2004) Genetic dissection of GABAB receptor function in mice. Other [Details]
(2004)Mapping of the binding Site of the GABAB positive modulator GS39783 by use of interspecies Rat/Drosophila Subunit Combinations.
Dupuis D.S., Relkovic D., Cryan J.F., Kaupmann K.; (2004) Mapping of the binding Site of the GABAB positive modulator GS39783 by use of interspecies Rat/Drosophila Subunit Combinations. Other [Details]
(2004)Global Down-Regulation Of Gene Expression In The Brain Using RNA Interference: Implications For Target Characterization In Psychiatric And Neurological Disorders.
Thakker D.R., Natt F., Maier R., Muller M., Van Der Putten H., Hoyer D., Cryan, J.F.; (2004) Global Down-Regulation Of Gene Expression In The Brain Using RNA Interference: Implications For Target Characterization In Psychiatric And Neurological Disorders. Other [Details]
(2004)Early deprivation leads to reduced motivation for reward that can be restored with fluoxetine in adult wistar rats.
Russig H., Ruedi-Bettschen D., Feldon J., Wrynn A., Cryan J.F., Pryce C.R.; (2004) Early deprivation leads to reduced motivation for reward that can be restored with fluoxetine in adult wistar rats. Other [Details]
(2004)GABAB Receptor-Mediated Antidepressant-Like Behaviour Is Serotonin Dependent.
Slattery D.A., Desrayaud S., Cryan J.F.; (2004) GABAB Receptor-Mediated Antidepressant-Like Behaviour Is Serotonin Dependent. Other [Details]
(2004)Altered sensitivity to the pharmacological effects of the GABAB receptor agonist baclofen in different mouse strains.
L.H. Jacobson, Cryan, J.F.; (2004) Altered sensitivity to the pharmacological effects of the GABAB receptor agonist baclofen in different mouse strains. Other [Details]
(2004)Positive Allosteric Modulation of ƒ×-Aminobutyric AcidB Receptors.
Urwyler S., Cryan J.F., Dupuis D.S., Gjoni T., Lingenhoehl K., Mombereau C., Mosbacher J., Pozza M.F. and Kaupmann K.; (2004) Positive Allosteric Modulation of ƒ×-Aminobutyric AcidB Receptors. Other [Details]
(2005)Lentiviral vector-mediated transgene expression in vitro and in vivo neuronal models.
Pun S., Osinde M., Stoehr N., Senechal Y., Schade A., Cryan J.F., Dev K.K.; (2005) Lentiviral vector-mediated transgene expression in vitro and in vivo neuronal models. Other [Details]
(2005)Behavioural and neurochemical consequences of siRNA-induced knockdown of serotonin and dopamine transporters in the adult mouse brain: Implications for validation of novel therapeutic targets for psychiatric illnesses.
Thakker D.R., Natt F., Hüsken D., Muller M., Maier R., van der Putten H., Hoyer D., Cryan, J.F.; (2005) Behavioural and neurochemical consequences of siRNA-induced knockdown of serotonin and dopamine transporters in the adult mouse brain: Implications for validation of novel therapeutic targets for psychiatric illnesses. Other [Details]
(2005)A role for the anterior cingulate cortex in amygdala-dependent fear processes: behavioral studies in the rat.
Bissiere, S. Neijt H.C., Lecourtier L., Olpe H.R., Cryan J.F.; (2005) A role for the anterior cingulate cortex in amygdala-dependent fear processes: behavioral studies in the rat. Other [Details]
(2005)Investigation of the molecular markers underlying the anti-addictive effects of GABAB receptor agonists and positive modulators.
Lhuillier L., Mombereau C., Cryan J.F., Kaupmann K.; (2005) Investigation of the molecular markers underlying the anti-addictive effects of GABAB receptor agonists and positive modulators. Other [Details]
(2005)Behavioural and neurochemical consequences of siRNA-induced knockdown of serotonin and dopamine transporters in the adult mouse brain: Implications for validation of novel antidepressant targets.
Thakker D.R., Natt F., Hüsken D., Maier R., van der Putten H., Hoyer D., Cryan J.F.; (2005) Behavioural and neurochemical consequences of siRNA-induced knockdown of serotonin and dopamine transporters in the adult mouse brain: Implications for validation of novel antidepressant targets. Other [Details]
(2005)GABAB receptor positive modulation as a novel therapeutic approach to drug dependence: Blockade of the rewarding and psychostimulant effects of cocaine.
Slattery D.A., Mombereau C., Froestl W., Markou A., Kaupmann K. and Cryan, J.F.; (2005) GABAB receptor positive modulation as a novel therapeutic approach to drug dependence: Blockade of the rewarding and psychostimulant effects of cocaine. Other [Details]
(2006)Evaluation of Reward Processes In An Animal Model of Depression.
Slattery, DA, Markou, A, Cryan, JF; (2006) Evaluation of Reward Processes In An Animal Model of Depression. Other [Details]
(2006)Evaluation of Reward Processes In An Animal Model of Depression.
Slattery, DA, Cryan, JF, Markou, A; (2006) Evaluation of Reward Processes In An Animal Model of Depression. Other [Details]
(2006)Emerging Use of Rna Interference to Understand The Role of Genes In Anxiety.
Cryan, JF, Thakker, DR, van der Putten, H, Flor, PJ, Hoyer, D; (2006) Emerging Use of Rna Interference to Understand The Role of Genes In Anxiety. Other [Details]
(2006)Molecular Dissection of The Role of Gaba1 Receptor Isoforms 1a and 1b In Anxiety-Related Behaviour.
Jacobson, LH, Neijt, HC, Bettler, B, Kaupmann, K, Cryan, JF; (2006) Molecular Dissection of The Role of Gaba1 Receptor Isoforms 1a and 1b In Anxiety-Related Behaviour. Other [Details]
(2006)The Infralimbic Cortex Modulates Stress-Induced Coping Behaviour - Implications For Depression.
Slattery, DA, Cryan, JF; (2006) The Infralimbic Cortex Modulates Stress-Induced Coping Behaviour - Implications For Depression. Other [Details]
(2006)Global Down-Regulation of Gene Expression In The Brain Using Rna Interference, With Emphasis On Monoamine Transporters and Gpcrs: Implications For Target Characterization In Psychiatric and Neurological Disorders.
Hoyer, D, Thakker, DR, Natt, F, Maier, R, Huesken, D, Muller, M, Flor, P, van der Putten, H, Schmutz, M, Bilbe, G, Cryan, JF; (2006) Global Down-Regulation of Gene Expression In The Brain Using Rna Interference, With Emphasis On Monoamine Transporters and Gpcrs: Implications For Target Characterization In Psychiatric and Neurological Disorders. Other [DOI] [Details]
(2007)Assessing The Genetic Influence On Anxiety Behaviour and Stress-Induced Brain Activation In The Mouse.
Mahony, CMO, Sweeney, F, Daly, E, Dinan, TG, Cryan, JF; (2007) Assessing The Genetic Influence On Anxiety Behaviour and Stress-Induced Brain Activation In The Mouse. Other [Details]
(2007)Depressive Behaviours and Alterations In The Immune and Stress Response Systems Following Neonatal Maternal Separation.
Mahony, SO, Clarke, G, Mahony, LO, Quigley, E, Cryan, J, Dinan, T; (2007) Depressive Behaviours and Alterations In The Immune and Stress Response Systems Following Neonatal Maternal Separation. Other [Details]
(2008)Differential Expression of Mglur7 In Two Animal Models of Depression.
O'Mahony, CM, Bravo, J, Dinan, TG, Cryan, JF; (2008) Differential Expression of Mglur7 In Two Animal Models of Depression. Other [Details]
(2008)Aberrant Lps-Induced Cytokine Responses In Mice Following Stress: Relevance to Major Depression.
Browne, CA, O'Brien, F, Connor, TJ, Dinan, TG, Cryan, JF; (2008) Aberrant Lps-Induced Cytokine Responses In Mice Following Stress: Relevance to Major Depression. Other [Details]
(2008)Genetic Influences On Hippocampal Susceptibility to Cell Death Following Immune Activation.
O'Connor, RM, McKernan, DR, Browne, C, Dinan, TG, Cryan, JF; (2008) Genetic Influences On Hippocampal Susceptibility to Cell Death Following Immune Activation. Other [Details]
(2008)The Effects of Acetylcholinesterase Inhibitor Pyridostigmine On Inflammatory Responses In An Animal Model of Irritable Bowel Syndrome.
Bravo, JA, Dinan, TG, Cryan, JF; (2008) The Effects of Acetylcholinesterase Inhibitor Pyridostigmine On Inflammatory Responses In An Animal Model of Irritable Bowel Syndrome. Other [Details]
(2008)Gobal Down-Regulation of Gene Expression In The Brain Using Rna Interference, With Emphasis On Neuropeptides, Gpcrs and Monoamine Transporters.
Hoyer, D, Thakker, DR, Natt, F, Maier, R, Huesken, D, Mueller, M, Flor, PJ, van der Putten, H, Schmutz, M, Cryan, JF; (2008) Gobal Down-Regulation of Gene Expression In The Brain Using Rna Interference, With Emphasis On Neuropeptides, Gpcrs and Monoamine Transporters. Other [Details]
(2008)Aberrant Cytokine Response to Stress In Balb/C Mice After Lipopolysaccharide (Lps) Challenge: Relevance of Tryptophan Hydroxylase 2.
Browne, CA, O'Brien, F, Connor, TJ, Cryan, JF; (2008) Aberrant Cytokine Response to Stress In Balb/C Mice After Lipopolysaccharide (Lps) Challenge: Relevance of Tryptophan Hydroxylase 2. Other [Details]
(2008)The Effects of Acute and Chronic Stress On Mglur7 and Bdnf Gene Expression In Two Inbred Strains of Mice Which Differ In Emotionality.
O'Mahony, CM, Dinan, TG, Cryan, JF; (2008) The Effects of Acute and Chronic Stress On Mglur7 and Bdnf Gene Expression In Two Inbred Strains of Mice Which Differ In Emotionality. Other [Details]
(2008)Altered Stress-Related Gene Expression In The Hippocampus of A Gentetic Model of Anxiety & Depression.
Bravo, JA, Dinan, TG, Cryan, JF; (2008) Altered Stress-Related Gene Expression In The Hippocampus of A Gentetic Model of Anxiety & Depression. Other [Details]
(2008)Balb/C Mice As A Model of Aberrant Stress-Induced Cytokine Expression: Relevence to Major Depression.
Browne, CA, O'Brien, F, Connor, TJ, Dinan, TG, Cryan, JF; (2008) Balb/C Mice As A Model of Aberrant Stress-Induced Cytokine Expression: Relevence to Major Depression. Other [Details]
(2008)Differential Activation of The Prefrontal Cortex In Response to Stress and Colonic Rectal Distension In A Genetically Susceptible Model of Depression & Irritable Bowel Syndrome (Ibs).
Gibney, SM, Gosselin, RD, Dinan, TG, Cryan, JF; (2008) Differential Activation of The Prefrontal Cortex In Response to Stress and Colonic Rectal Distension In A Genetically Susceptible Model of Depression & Irritable Bowel Syndrome (Ibs). Other [Details]
(2008)Region Specific Decrease In Glial Fibrillary Acidic Protein (Gfap) Immunoreactivity In The Brain of A Genetic Rat Model of Depression.
Gosselin, RD, Gibney, S, O'Malley, D, Dinan, TG, Cryan, JF; (2008) Region Specific Decrease In Glial Fibrillary Acidic Protein (Gfap) Immunoreactivity In The Brain of A Genetic Rat Model of Depression. Other [Details]
(2008)Tryptophan Degradation and Irritable Bowel Syndrome (Ibs) - Evidence of An Immune Mediated Indoleamine-2,3-Dioxygenase (Ido) Activation In A Male Cohort.
Clarkc, G, Fitzgerald, P, Cryan, JF, Dinan, TG; (2008) Tryptophan Degradation and Irritable Bowel Syndrome (Ibs) - Evidence of An Immune Mediated Indoleamine-2,3-Dioxygenase (Ido) Activation In A Male Cohort. Other [Details]
(2009)A distinct subset of submucosal mast cells undergoes hyperplasia following neonatal maternal separation: a role in visceral hypersensitivity?.
Hyland, NP,Julio-Pieper, M,O'Mahony, SM,Bulmer, DC,Lee, K,Quigley, EM,Dinan, TG,Cryan, JF (2009) A distinct subset of submucosal mast cells undergoes hyperplasia following neonatal maternal separation: a role in visceral hypersensitivity?. Other [DOI] [Details]
(2009)Altered Expression of Hippocampal Mglur7 Mrna In A Model of Depression.
O'Mahony, C, Dinan, TG, Cryan, JF; (2009) Altered Expression of Hippocampal Mglur7 Mrna In A Model of Depression. Other [Details]
(2009)Mice Are Resistant to Early-Life Stress-Induced Alterations In Adult Behaviour.
Savignac, HM, Dinan, TG, Cryan, JF; (2009) Mice Are Resistant to Early-Life Stress-Induced Alterations In Adult Behaviour. Other [Details]

Newspaper Articles

 YearPublication
(2016)A trigger for neurodegeneration?.
Stilling, RM,Cryan, JF (2016) A trigger for neurodegeneration?. Newspaper Articles [DOI] [Details]
(2010)Banning mephedrone won't stop next wave.
Keating J.J., Cryan J.F.; (2010) Banning mephedrone won't stop next wave. Irish Examiner: Newspaper Articles [Details]

Review Articles

 YearPublication
(2014)Biological and psychological markers of stress in humans: Focus on the Trier Social Stress Test.
Allen, A.P., Kennedy, P.J., Cryan, J.F., Dinan, T.G., Clarke, G (2014) Biological and psychological markers of stress in humans: Focus on the Trier Social Stress Test. Review Articles [DOI] [Details]
(2009)Irritable bowel syndrome: towards biomarker identification.
Clarke G, Quigley EMM, Cryan JF, Dinan TG (2009) Irritable bowel syndrome: towards biomarker identification. Review Articles [Details]
(2011)Brain-Gut-Microbe communication in health and disease.
Grenham S, Clarke G, Cryan JF, Dinan TG (2011) Brain-Gut-Microbe communication in health and disease. Review Articles [Details]
(2012)Gut Memories: Towards a Cognitive Neurobiology of Irritable Bowel Syndrome.
Kennedy P, Clarke G, Groeger J, Quigley EMM, Cryan J, Dinan T (2012) Gut Memories: Towards a Cognitive Neurobiology of Irritable Bowel Syndrome. Review Articles [Details]
(2012)Probiotics for the Treatment of Irritable Bowel Syndrome: Focus on Lactic Acid Bacteria.
Clarke G, Cryan JF, Dinan TG, Quigley EM (2012) Probiotics for the Treatment of Irritable Bowel Syndrome: Focus on Lactic Acid Bacteria. Review Articles [Details]
(2005)New medications for smoking cessation: beyond NRT and bupropion.
Cryan J.F.; (2005) New medications for smoking cessation: beyond NRT and bupropion. Review Articles [Details]
(2005)mGluR7 Plays a Key Role in the Modulation of Anxiety Behavior: Evidence from mGluR7 Knockout Mice and siRNA-induced Knockdown in the Adult Mouse Brain.
Cryan J.F.; (2005) mGluR7 Plays a Key Role in the Modulation of Anxiety Behavior: Evidence from mGluR7 Knockout Mice and siRNA-induced Knockdown in the Adult Mouse Brain. Review Articles [Details]
(2005)Use of RNAi in Target Validation for Neuropsychiatric Disorders.
Cryan J.F.; (2005) Use of RNAi in Target Validation for Neuropsychiatric Disorders. Review Articles [Details]
(2005)The use of genetically modified mice to understand the role of metabotropic glutamate 7 Receptors in Anxiety.
Cryan J.F.; (2005) The use of genetically modified mice to understand the role of metabotropic glutamate 7 Receptors in Anxiety. Review Articles [Details]
(2004)The Modified Rat Forced Swim Test:A tool to assess the role of monoamines in antidepressant action.
Cryan J.F.; (2004) The Modified Rat Forced Swim Test:A tool to assess the role of monoamines in antidepressant action. Review Articles [Details]
(2004)Targeting the GABAB receptor for the development of anxiolytic and antidepressants: Recent advances with novel pharmacological and genetic tools.
Cryan J.F.; (2004) Targeting the GABAB receptor for the development of anxiolytic and antidepressants: Recent advances with novel pharmacological and genetic tools. Review Articles [Details]
(2004)In search of a depressed mouse: models for studying depression-related behaviour in genetically modified mice.
Cryan J.F.; (2004) In search of a depressed mouse: models for studying depression-related behaviour in genetically modified mice. Review Articles [Details]
(2003)Murine models of depression: Utility for knockout and transgenic behavioral studies.
Cryan, J.F.; (2003) Murine models of depression: Utility for knockout and transgenic behavioral studies. Review Articles [Details]
(2000)Antidepressants associated with norepinephrine and serotonin pathways elicit distinct behaviors in a modified forced swim test.
Cryan, J.F., Page, M.E. and Lucki, I.; (2000) Antidepressants associated with norepinephrine and serotonin pathways elicit distinct behaviors in a modified forced swim test. Review Articles [Details]
(1997)Combining pindolol and paroxetine in an animal model of chronic antidepressant action - Can early onset of action be detected?.
Cryan J.F., McGrath, C., Leonard B.E. and Norman T.R; (1997) Combining pindolol and paroxetine in an animal model of chronic antidepressant action - Can early onset of action be detected?. Review Articles [Details]
(1996)The effects of the 5-HT1A agonist flesinoxan, in three paradigms for assessing antidepressant potential in the rat.
Cryan J.F., Redmond A.M., Kelly J.P. and Leonard B.E.; (1996) The effects of the 5-HT1A agonist flesinoxan, in three paradigms for assessing antidepressant potential in the rat. Review Articles [Details]

Professional Activities

Honours and Awards

 YearTitleAwarding Body
2007National Institutes for Mental Health, NIH, USA. Distinguished Lecturer National Institutes for Mental Health, NIH, USA.
2013University of Utrecht Award for Excellence in Pharmaceutical Research University of Utrecht
2012University College Cork Researcher of the Year University College Cork
2013Conway Review Lecture Royal Academy of Medicine in Ireland
2013De Pazzi Lecture University College Cork
2006European College of Neuropsychopharmacology Fellowship Award European College of Neuropsychopharmacology
2006Wyeth Psychopharmacology Award of British Association of Psychopharmacology British Association of Psychopharmacology
2005Keynote speaker at New York Academy of the Sciences New York Academy of the Sciences
2005Young Scientist Award from Foundation of the European Behavioural Pharmacology Society Foundation of the European Behavioural Pharmacology Society
2005Novartis Neuroscience Recognition Award Novartis Pharma AG

Patents

 Patent NumberTitleGranted
WO/2011/058535Probiotic bifidobacterium strain 19-MAY-11
WO 2004/071152Use of S-10 hydroxy-10, 11-dihydro-carbamazepine for the treatment of anxiety and bipolar disorders 01-JAN-04

Committees

 CommitteeFunctionFrom / To
External Examiner: University Birmingham, BMed Sci Degree 2008 /
External Examiner: Galway-Mayo Institute of Technology, Bachelor of Science (Honours) in Applied Biology and Biopharmaceutical Science 2008 / 2008
PhD Examiner Mr. Lucas Lecourtier, University of Bordeaux /
PhD Examiner Mr Danny Allen, Genetics Dept., Trinity College Dublin /
PhD Examiner Mr. Lawrence Tam, Genetics Dept., Trinity College Dublin /
Quality Review: NUI Galway, BSc Biotechnology Programme /

Employment

 EmployerPositionFrom / To
School of Pharmacy, University College Cork Senior Lecturer/Principal Investigator01-JUL-06 /
University College Cork Lecturer01-JAN-05 / 31-DEC-06
Novartis Institutes for BioMedical Research LabHead Behavioural Pharmacology01-JAN-02 / 31-DEC-05
The Scripps Research Institute Senior Postdoctoral Fellow01-JAN-01 / 31-DEC-01

Education

 YearInstitutionQualificationSubject
1995NUI Galway BSc Hons, (NUI,Galway)Biochemistry
1998NUI Galway PHDPharmacology

Consultancy

 ClientDescription
National Institutes for Drug Abuse (NIDA): Review and Evaluation of NIDA Targets for Potential NIH Roadmap Library Screening

Journal Activities

 JournalRoleTo / From
Proceedings Of The National Academy Of Science Usa Referee-
Science Referee-
Frontiers In Pharmacology Editor-
Science Referee-
Plos Biology Referee-
Neuropharmacology Editor-
Psychopharmacology Editor-
Brain Research Member of Editorial Board-
Behavioural Pharmacology Member of Editorial Board-
Neuroscience And Biobehavioral Reviews Member of Editorial Board-
Behavioural Brain Research Referee-
Behavior Genetics Referee-
Behavioural Pharmacology Referee-
Brain Research Referee-
British Journal Of Pharmacology Editor-
European Journal Of Pharmacology Referee-
Experimental Brain Research Referee-
Genome Research Referee-
Human Psychopharmacology Referee-
Human Molecular Genetics Referee-
Neuropsychopharmacology Referee-
Journal Of Neural Transmission Referee-
Journal Of Neurochemistry Referee-
Journal Of Neuroscience Referee-
Journal Of Pharmacology And Experimental Therapeutics Referee-
Journal Of Psychopharmacology Referee-
Neuropharmacology Referee-
Neuropsychopharmacology Referee-
Neuroscience Referee-
Neuroscience And Biobehavioral Reviews Referee-
Pharmacogenomics Referee-
Pharmacology Biochemistry And Behavior Referee-
Proceedings Of The National Academy Of Sciences Of The United States Of America Referee-
Psychiatry Research Referee-
Psychopharmacology Referee-
Psychoneuroendocrinology Referee-
Stress And Health Referee-
Synapse (New York, N.Y.) Referee-
Trends In Pharmacological Sciences Referee-

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Research and Innovation

Taighde agus Nuálaíocht

Office of Vice President for Research & Innovation 4th Floor Block E, Food Science Building UCC

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