TY  - JOUR
  - Buckley, CM,Madden, J,Balanda, K,Barron, S,Fahy, L,Harrington, J,Perry, IJ,Kearney, PM
  - 2013
  - October
  - Diabetic Medicine
  - Pre-diabetes in adults 45 years and over in Ireland: the Survey of Lifestyle, Attitudes and Nutrition in Ireland 2007
  - Validated
  - Altmetric: 6 ()
  - DIABETES-MELLITUS US POPULATION HIGH-RISK PREVALENCE A1C METAANALYSIS HEMOGLOBIN DIAGNOSIS PEOPLE HEALTH
  - 30
  - 1198
  - 1203
  - ObjectivesPre-diabetes is an important indicator of future diabetes burden and many countries are reporting prevalence estimates of pre-diabetes. To date in Ireland, estimates of the prevalence of pre-diabetes were unavailable. Our objectives were to estimate the prevalence of pre-diabetes in a nationally representative sample of Irish adults and to explore determinants of pre-diabetes.MethodsThe Survey of Lifestyle Attitudes and Nutrition 2007 was a cross-sectional survey on health and lifestyle in a nationally representative sample of Irish adults. Analysis was performed on a subsample of 1132 participants 45years who provided blood samples. Determination of pre-diabetes was based on American Diabetes Association HbA(1c) cut points of 39-46mmol/mol (5.7-6.4%). To explore determinants, we modelled pre-diabetes prevalence as a function of a set of health system and socio-demographic variables using logistic regression.ResultsThe overall weighted prevalence estimate of pre-diabetes in participants 45years was 19.8% (95%CI 16.4-23.9). There was no significant difference between age or gender-specific prevalence rates. Obesity was significantly associated with pre-diabetes on univariate and multivariate analysis. Population attributable fraction estimates for excess BMI, physical inactivity and poor diet as causes of pre-diabetes were 31.3% (95%CI -3.9 to 54.5), 10.0% (95%CI -2.7 to 21.3) and 6.1% (95%CI -4.9 to 15.9), respectively.ConclusionsThe high levels of pre-diabetes detected in this study are worrying. Population level interventions to address diet and lifestyle factors are needed urgently to prevent progression to diabetes in high-risk individuals.
  - 10.1111/dme.12226
DA  - 2013/10
ER  - 

@article{V243944278,
   = {Buckley,  CM and Madden,  J and Balanda,  K and Barron,  S and Fahy,  L and Harrington,  J and Perry,  IJ and Kearney,  PM },
   = {2013},
   = {October},
   = {Diabetic Medicine},
   = {Pre-diabetes in adults 45 years and over in Ireland: the Survey of Lifestyle, Attitudes and Nutrition in Ireland 2007},
   = {Validated},
   = {Altmetric: 6 ()},
   = {DIABETES-MELLITUS US POPULATION HIGH-RISK PREVALENCE A1C METAANALYSIS HEMOGLOBIN DIAGNOSIS PEOPLE HEALTH},
   = {30},
  pages = {1198--1203},
   = {{ObjectivesPre-diabetes is an important indicator of future diabetes burden and many countries are reporting prevalence estimates of pre-diabetes. To date in Ireland, estimates of the prevalence of pre-diabetes were unavailable. Our objectives were to estimate the prevalence of pre-diabetes in a nationally representative sample of Irish adults and to explore determinants of pre-diabetes.MethodsThe Survey of Lifestyle Attitudes and Nutrition 2007 was a cross-sectional survey on health and lifestyle in a nationally representative sample of Irish adults. Analysis was performed on a subsample of 1132 participants 45years who provided blood samples. Determination of pre-diabetes was based on American Diabetes Association HbA(1c) cut points of 39-46mmol/mol (5.7-6.4%). To explore determinants, we modelled pre-diabetes prevalence as a function of a set of health system and socio-demographic variables using logistic regression.ResultsThe overall weighted prevalence estimate of pre-diabetes in participants 45years was 19.8% (95%CI 16.4-23.9). There was no significant difference between age or gender-specific prevalence rates. Obesity was significantly associated with pre-diabetes on univariate and multivariate analysis. Population attributable fraction estimates for excess BMI, physical inactivity and poor diet as causes of pre-diabetes were 31.3% (95%CI -3.9 to 54.5), 10.0% (95%CI -2.7 to 21.3) and 6.1% (95%CI -4.9 to 15.9), respectively.ConclusionsThe high levels of pre-diabetes detected in this study are worrying. Population level interventions to address diet and lifestyle factors are needed urgently to prevent progression to diabetes in high-risk individuals.}},
   = {10.1111/dme.12226},
  source = {IRIS}
}