IRIS publication 122827888
Crohn's disease
RIS format for Endnote and similar
TY - JOUR - Shanahan, F. - 2002 - Lancet - Crohn's disease - Validated - () - 359 - 9300 - 62 - 69 - Crohn's disease is a disorder mediated by T lymphocytes which arises In genetically susceptible Individuals as a result of a breakdown in the regulatory constraints on mucosal immune responses to enteric bacteria, Regulation of Immune reactivity to enteric antigens has improved understanding of the pathophysiological mechanisms of Crohn's disease, and has expanded therapeutic options for patients with this disorder. Disease heterogeneity Is probable, with various underlying defects associated with a similar pathophysiological outcome. Although most conventional drug treatments are directed at modification of host response, therapeutic manipulation of the enteric flora Is becoming a realistic option. DA - 2002/NaN ER -
BIBTeX format for JabRef and similar
@article{V122827888, = {Shanahan, F. }, = {2002}, = {Lancet}, = {Crohn's disease}, = {Validated}, = {()}, = {359}, = {9300}, pages = {62--69}, = {{Crohn's disease is a disorder mediated by T lymphocytes which arises In genetically susceptible Individuals as a result of a breakdown in the regulatory constraints on mucosal immune responses to enteric bacteria, Regulation of Immune reactivity to enteric antigens has improved understanding of the pathophysiological mechanisms of Crohn's disease, and has expanded therapeutic options for patients with this disorder. Disease heterogeneity Is probable, with various underlying defects associated with a similar pathophysiological outcome. Although most conventional drug treatments are directed at modification of host response, therapeutic manipulation of the enteric flora Is becoming a realistic option.}}, source = {IRIS} }
Data as stored in IRIS
AUTHORS | Shanahan, F. | ||
YEAR | 2002 | ||
MONTH | |||
JOURNAL_CODE | Lancet | ||
TITLE | Crohn's disease | ||
STATUS | Validated | ||
TIMES_CITED | () | ||
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VOLUME | 359 | ||
ISSUE | 9300 | ||
START_PAGE | 62 | ||
END_PAGE | 69 | ||
ABSTRACT | Crohn's disease is a disorder mediated by T lymphocytes which arises In genetically susceptible Individuals as a result of a breakdown in the regulatory constraints on mucosal immune responses to enteric bacteria, Regulation of Immune reactivity to enteric antigens has improved understanding of the pathophysiological mechanisms of Crohn's disease, and has expanded therapeutic options for patients with this disorder. Disease heterogeneity Is probable, with various underlying defects associated with a similar pathophysiological outcome. Although most conventional drug treatments are directed at modification of host response, therapeutic manipulation of the enteric flora Is becoming a realistic option. | ||
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