Non-Linkage of a T-Cell Receptor-Gamma Chain Microsatellite (D7s485) to Rheumatoid-Arthritis, in Multiplex Families

Typeset version

 

TY  - JOUR
  - Mcdermott, M.,Hsu, C.,Molloy, M. G.,Mulcahy, B.,Phelan, M.,Shanahan, F.,Ogara, F.,Adams, C.,Rubin, L. A.,Clegg, D. O.,Husebye, D.,Amos, C. I.,Ward, R. H.,Kastner, D. L.
  - 1995
  - February
  - Non-Linkage of a T-Cell Receptor-Gamma Chain Microsatellite (D7s485) to Rheumatoid-Arthritis, in Multiplex Families
  - Validated
  - ()
  - 8
  - 11
  - 131
  - 138131
  - A highly informative microsatellite marker, D7S485, from the T-cell receptor gamma (TCRG) locus, has been used to study segregation of TCRG genes in 26 multiplex rheumatoid arthritis (RA) families. We used the sib-pair method to assess excess identity-by-descent sharing among affected members in these families and the LINKAGE package of programs was used to calculate two-point lod scores far the D7S485 marker. There was no evidence for segregation of TCRG genes with RA in affected siblings and significantly negative lad scores were obtained from Linkage analyses using bath autosomal dominant and recessive models of inheritance.A highly informative microsatellite marker, D7S485, from the T-cell receptor gamma (TCRG) locus, has been used to study segregation of TCRG genes in 26 multiplex rheumatoid arthritis (RA) families. We used the sib-pair method to assess excess identity-by-descent sharing among affected members in these families and the LINKAGE package of programs was used to calculate two-point lod scores far the D7S485 marker. There was no evidence for segregation of TCRG genes with RA in affected siblings and significantly negative lad scores were obtained from Linkage analyses using bath autosomal dominant and recessive models of inheritance.
  - 0896-84110896-8411
  - ://WOS:A1995QF80900010://WOS:A1995QF80900010
DA  - 1995/02
ER  - 
@article{V235379998,
   = {Mcdermott,  M. and Hsu,  C. and Molloy,  M. G. and Mulcahy,  B. and Phelan,  M. and Shanahan,  F. and Ogara,  F. and Adams,  C. and Rubin,  L. A. and Clegg,  D. O. and Husebye,  D. and Amos,  C. I. and Ward,  R. H. and Kastner,  D. L. },
   = {1995},
   = {February},
   = {Non-Linkage of a T-Cell Receptor-Gamma Chain Microsatellite (D7s485) to Rheumatoid-Arthritis, in Multiplex Families},
   = {Validated},
   = {()},
   = {8},
   = {11},
  pages = {131--138131},
   = {{A highly informative microsatellite marker, D7S485, from the T-cell receptor gamma (TCRG) locus, has been used to study segregation of TCRG genes in 26 multiplex rheumatoid arthritis (RA) families. We used the sib-pair method to assess excess identity-by-descent sharing among affected members in these families and the LINKAGE package of programs was used to calculate two-point lod scores far the D7S485 marker. There was no evidence for segregation of TCRG genes with RA in affected siblings and significantly negative lad scores were obtained from Linkage analyses using bath autosomal dominant and recessive models of inheritance.A highly informative microsatellite marker, D7S485, from the T-cell receptor gamma (TCRG) locus, has been used to study segregation of TCRG genes in 26 multiplex rheumatoid arthritis (RA) families. We used the sib-pair method to assess excess identity-by-descent sharing among affected members in these families and the LINKAGE package of programs was used to calculate two-point lod scores far the D7S485 marker. There was no evidence for segregation of TCRG genes with RA in affected siblings and significantly negative lad scores were obtained from Linkage analyses using bath autosomal dominant and recessive models of inheritance.}},
  issn = {0896-84110896-8411},
   = {://WOS:A1995QF80900010://WOS:A1995QF80900010},
  source = {IRIS}
}
AUTHORSMcdermott, M.,Hsu, C.,Molloy, M. G.,Mulcahy, B.,Phelan, M.,Shanahan, F.,Ogara, F.,Adams, C.,Rubin, L. A.,Clegg, D. O.,Husebye, D.,Amos, C. I.,Ward, R. H.,Kastner, D. L.
YEAR1995
MONTHFebruary
JOURNAL_CODE
TITLENon-Linkage of a T-Cell Receptor-Gamma Chain Microsatellite (D7s485) to Rheumatoid-Arthritis, in Multiplex Families
STATUSValidated
TIMES_CITED()
SEARCH_KEYWORD
VOLUME8
ISSUE11
START_PAGE131
END_PAGE138131
ABSTRACTA highly informative microsatellite marker, D7S485, from the T-cell receptor gamma (TCRG) locus, has been used to study segregation of TCRG genes in 26 multiplex rheumatoid arthritis (RA) families. We used the sib-pair method to assess excess identity-by-descent sharing among affected members in these families and the LINKAGE package of programs was used to calculate two-point lod scores far the D7S485 marker. There was no evidence for segregation of TCRG genes with RA in affected siblings and significantly negative lad scores were obtained from Linkage analyses using bath autosomal dominant and recessive models of inheritance.A highly informative microsatellite marker, D7S485, from the T-cell receptor gamma (TCRG) locus, has been used to study segregation of TCRG genes in 26 multiplex rheumatoid arthritis (RA) families. We used the sib-pair method to assess excess identity-by-descent sharing among affected members in these families and the LINKAGE package of programs was used to calculate two-point lod scores far the D7S485 marker. There was no evidence for segregation of TCRG genes with RA in affected siblings and significantly negative lad scores were obtained from Linkage analyses using bath autosomal dominant and recessive models of inheritance.
PUBLISHER_LOCATION
ISBN_ISSN0896-84110896-8411
EDITION
URL://WOS:A1995QF80900010://WOS:A1995QF80900010
DOI_LINK
FUNDING_BODY
GRANT_DETAILS