TY  - JOUR
  - Doyle OM, Korotchikova I, Lightbody G, Marnane W, Kerins D, Boylan GB
  - 2009
  - August
  - Physiological Measurement
  - Heart rate variability during sleep in healthy term newborns in the early postnatal period.
  - Published
  - WOS: 37 ()
  - 30
  - 8
  - 847
  - 860
  - Normative time- and frequency-domain heart rate variability (HRV) measures were extracted during quiet sleep (QS) and active sleep (AS) periods in 30 healthy babies. All newborn infants studied were less than 12 h old and the sleep state was classified using multi-channel video EEG. Three bands were extracted from the heart rate (HR) spectrum: very low frequency (VLF), 0.01-0.04 Hz; low frequency (LF), 0.04-0.2 Hz, and high frequency (HF), >0.2 Hz. All metrics were averaged across all patients and per sleep state to produce a table of normative values. A noticeable peak corresponding to activity in the RSA band was found in 80% patients during QS and 0% of patients during AS, although some broadband activity was observed. The majority of HRV metrics showed a statistically significant separation between QS and AS. It can be concluded that (i) activity in the RSA band is present during QS in the healthy newborn, in the first 12 h of life, (ii) HRV measures are affected by sleep state and (iii) the averaged HRV metrics reported here could assist the interpretation of HRV data from newborns with neonatal illnesses.
  - 10.1088/0967-3334/30/8/009
DA  - 2009/08
ER  - 

@article{V58462160,
   = {Doyle OM,  Korotchikova I and  Lightbody G,  Marnane W and  Kerins D,  Boylan GB },
   = {2009},
   = {August},
   = {Physiological Measurement},
   = {Heart rate variability during sleep in healthy term newborns in the early postnatal period.},
   = {Published},
   = {WOS: 37 ()},
   = {30},
   = {8},
  pages = {847--860},
   = {{Normative time- and frequency-domain heart rate variability (HRV) measures were extracted during quiet sleep (QS) and active sleep (AS) periods in 30 healthy babies. All newborn infants studied were less than 12 h old and the sleep state was classified using multi-channel video EEG. Three bands were extracted from the heart rate (HR) spectrum: very low frequency (VLF), 0.01-0.04 Hz; low frequency (LF), 0.04-0.2 Hz, and high frequency (HF), >0.2 Hz. All metrics were averaged across all patients and per sleep state to produce a table of normative values. A noticeable peak corresponding to activity in the RSA band was found in 80% patients during QS and 0% of patients during AS, although some broadband activity was observed. The majority of HRV metrics showed a statistically significant separation between QS and AS. It can be concluded that (i) activity in the RSA band is present during QS in the healthy newborn, in the first 12 h of life, (ii) HRV measures are affected by sleep state and (iii) the averaged HRV metrics reported here could assist the interpretation of HRV data from newborns with neonatal illnesses.}},
   = {10.1088/0967-3334/30/8/009},
  source = {IRIS}
}