TY  - JOUR
  - Doyle, OM, Korotchikova, I, Lightbody, G, Marnane, W, Kerins, D, Boylan, GB
  - 2009
  - August
  - Physiological Measurement
  - Heart Rate Variability During Sleep In Healthy Term Newborns In The Early Postnatal Period
  - Validated
  - ()
  - 30
  - 8
  - 847
  - 860
  - Normative time-and frequency-domain heart rate variability (HRV) measures were extracted during quiet sleep (QS) and active sleep (AS) periods in 30 healthy babies. All newborn infants studied were less than 12 h old and the sleep state was classified using multi-channel video EEG. Three bands were extracted from the heart rate (HR) spectrum: very low frequency (VLF), 0.01-0.04 Hz; low frequency (LF), 0.04-0.2 Hz, and high frequency (HF), > 0.2 Hz. All metrics were averaged across all patients and per sleep state to produce a table of normative values. A noticeable peak corresponding to activity in the RSA band was found in 80% patients during QS and 0% of patients during AS, although some broadband activity was observed. The majority of HRV metrics showed a statistically significant separation between QS and AS. It can be concluded that (i) activity in the RSA band is present during QS in the healthy newborn, in the first 12 h of life, (ii) HRV measures are affected by sleep state and (iii) the averaged HRV metrics reported here could assist the interpretation of HRV data from newborns with neonatal illnesses..
  - DOI 10.1088/0967-3334/30/8/009
DA  - 2009/08
ER  - 

@article{V720288,
   = {Doyle,  OM and  Korotchikova,  I and  Lightbody,  G and  Marnane,  W and  Kerins,  D and  Boylan,  GB },
   = {2009},
   = {August},
   = {Physiological Measurement},
   = {Heart Rate Variability During Sleep In Healthy Term Newborns In The Early Postnatal Period},
   = {Validated},
   = {()},
   = {30},
   = {8},
  pages = {847--860},
   = {{Normative time-and frequency-domain heart rate variability (HRV) measures were extracted during quiet sleep (QS) and active sleep (AS) periods in 30 healthy babies. All newborn infants studied were less than 12 h old and the sleep state was classified using multi-channel video EEG. Three bands were extracted from the heart rate (HR) spectrum: very low frequency (VLF), 0.01-0.04 Hz; low frequency (LF), 0.04-0.2 Hz, and high frequency (HF), > 0.2 Hz. All metrics were averaged across all patients and per sleep state to produce a table of normative values. A noticeable peak corresponding to activity in the RSA band was found in 80% patients during QS and 0% of patients during AS, although some broadband activity was observed. The majority of HRV metrics showed a statistically significant separation between QS and AS. It can be concluded that (i) activity in the RSA band is present during QS in the healthy newborn, in the first 12 h of life, (ii) HRV measures are affected by sleep state and (iii) the averaged HRV metrics reported here could assist the interpretation of HRV data from newborns with neonatal illnesses..}},
   = {DOI 10.1088/0967-3334/30/8/009},
  source = {IRIS}
}