Altered FXR signaling is associated with bile acid dysmetabolism in short bowel syndrome-associated liver disease.

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TY  - JOUR
  - Pereira-Fantini PM, Lapthorne S, Joyce SA, Dellios NL, Wilson G, Fouhy F, Thomas SL, Scurr M, Hill C, Gahan CG, Cotter PD, Fuller PJ, Hardikar W, Bines JE
  - 2014
  - July
  - Journal of hepatology
  - Altered FXR signaling is associated with bile acid dysmetabolism in short bowel syndrome-associated liver disease.
  - Validated
  - Altmetric: 1 ()
  - Despite the mortality associated with liver disease observed in patients with short bowel syndrome (SBS), mechanisms underlying the development of SBS-associated liver disease (SBS-ALD) are poorly understood. This study examines the impact of bacterially-mediated bile acid (BA) dysmetabolism on FXR signaling pathways and clinical outcome in a piglet model of SBS-ALD.
  - 10.1016/j.jhep.2014.06.025
DA  - 2014/07
ER  - 
@article{V268806212,
   = {Pereira-Fantini PM,  Lapthorne S and  Joyce SA,  Dellios NL and  Wilson G,  Fouhy F and  Thomas SL,  Scurr M and  Hill C,  Gahan CG and  Cotter PD,  Fuller PJ and  Hardikar W,  Bines JE },
   = {2014},
   = {July},
   = {Journal of hepatology},
   = {Altered FXR signaling is associated with bile acid dysmetabolism in short bowel syndrome-associated liver disease.},
   = {Validated},
   = {Altmetric: 1 ()},
   = {{Despite the mortality associated with liver disease observed in patients with short bowel syndrome (SBS), mechanisms underlying the development of SBS-associated liver disease (SBS-ALD) are poorly understood. This study examines the impact of bacterially-mediated bile acid (BA) dysmetabolism on FXR signaling pathways and clinical outcome in a piglet model of SBS-ALD.}},
   = {10.1016/j.jhep.2014.06.025},
  source = {IRIS}
}
AUTHORSPereira-Fantini PM, Lapthorne S, Joyce SA, Dellios NL, Wilson G, Fouhy F, Thomas SL, Scurr M, Hill C, Gahan CG, Cotter PD, Fuller PJ, Hardikar W, Bines JE
YEAR2014
MONTHJuly
JOURNAL_CODEJournal of hepatology
TITLEAltered FXR signaling is associated with bile acid dysmetabolism in short bowel syndrome-associated liver disease.
STATUSValidated
TIMES_CITEDAltmetric: 1 ()
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ABSTRACTDespite the mortality associated with liver disease observed in patients with short bowel syndrome (SBS), mechanisms underlying the development of SBS-associated liver disease (SBS-ALD) are poorly understood. This study examines the impact of bacterially-mediated bile acid (BA) dysmetabolism on FXR signaling pathways and clinical outcome in a piglet model of SBS-ALD.
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DOI_LINK10.1016/j.jhep.2014.06.025
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