The impact of iron on Listeria monocytogenes; inside and outside the host.

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TY  - JOUR
  - McLaughlin HP, Hill C, Gahan CG
  - 2011
  - November
  - Current Opinion In Biotechnology
  - The impact of iron on Listeria monocytogenes; inside and outside the host.
  - Published
  - ()
  - 22
  - 2
  - 194
  - 199
  - As iron is vital for all cells, host sequestration of iron provides a significant barrier to bacterial infection. The absolute requirement for iron has driven the evolution of refined systems by which pathogenic bacteria such as Listeria monocytogenes can competitively acquire this element during host infection. This process is coordinated, at least partly, by the Ferric Uptake Regulator (Fur). Recent studies have identified loci within the listerial Fur-regulon and have characterized specific systems involved in iron uptake from various sources. This work has greatly advanced our knowledge of the mechanisms underpinning iron homeostasis in L. monocytogenes. A greater understanding of the molecular mechanisms by which pathogenic bacteria acquire iron is significant from both a food safety and public-health perspective.
  - 10.1016/j.copbio.2010.10.005
DA  - 2011/11
ER  - 
@article{V69454826,
   = {McLaughlin HP,  Hill C and  Gahan CG },
   = {2011},
   = {November},
   = {Current Opinion In Biotechnology},
   = {The impact of iron on Listeria monocytogenes; inside and outside the host.},
   = {Published},
   = {()},
   = {22},
   = {2},
  pages = {194--199},
   = {{As iron is vital for all cells, host sequestration of iron provides a significant barrier to bacterial infection. The absolute requirement for iron has driven the evolution of refined systems by which pathogenic bacteria such as Listeria monocytogenes can competitively acquire this element during host infection. This process is coordinated, at least partly, by the Ferric Uptake Regulator (Fur). Recent studies have identified loci within the listerial Fur-regulon and have characterized specific systems involved in iron uptake from various sources. This work has greatly advanced our knowledge of the mechanisms underpinning iron homeostasis in L. monocytogenes. A greater understanding of the molecular mechanisms by which pathogenic bacteria acquire iron is significant from both a food safety and public-health perspective.}},
   = {10.1016/j.copbio.2010.10.005},
  source = {IRIS}
}
AUTHORSMcLaughlin HP, Hill C, Gahan CG
YEAR2011
MONTHNovember
JOURNAL_CODECurrent Opinion In Biotechnology
TITLEThe impact of iron on Listeria monocytogenes; inside and outside the host.
STATUSPublished
TIMES_CITED()
SEARCH_KEYWORD
VOLUME22
ISSUE2
START_PAGE194
END_PAGE199
ABSTRACTAs iron is vital for all cells, host sequestration of iron provides a significant barrier to bacterial infection. The absolute requirement for iron has driven the evolution of refined systems by which pathogenic bacteria such as Listeria monocytogenes can competitively acquire this element during host infection. This process is coordinated, at least partly, by the Ferric Uptake Regulator (Fur). Recent studies have identified loci within the listerial Fur-regulon and have characterized specific systems involved in iron uptake from various sources. This work has greatly advanced our knowledge of the mechanisms underpinning iron homeostasis in L. monocytogenes. A greater understanding of the molecular mechanisms by which pathogenic bacteria acquire iron is significant from both a food safety and public-health perspective.
PUBLISHER_LOCATION
ISBN_ISSN
EDITION
URL
DOI_LINK10.1016/j.copbio.2010.10.005
FUNDING_BODY
GRANT_DETAILS