The genus Lactobacillus - a genomic basis for understanding its diversity

Typeset version

 

TY  - JOUR
  - Claesson, MJ,van Sinderen, D,O'Toole, PW
  - 2007
  - April
  - Fems Microbiology Letters
  - The genus Lactobacillus - a genomic basis for understanding its diversity
  - Validated
  - ()
  - Lactobacillus lactobacilli genomics genome sequencing phylogenetic diversity LACTIC-ACID BACTERIA ACIDOPHILUS NCFM FUNCTIONAL-ANALYSIS JOHNSONII NCC-533 FUTURE-PROSPECTS SALIVARIUS PLANTARUM SEQUENCE PROBIOTICS SAKEI
  - 269
  - 22
  - 28
  - The genus Lactobacillus is a diverse group that includes many species used in food production and preservation. Some lactobacilli are considered probiotic, conferring health benefits upon the host. The heterogeneity of this genus poses challenges and opportunities when characterizing or exploiting individual strains. To date, 10 Lactobacillus genome sequences have been published, and at least 11 more sequencing projects are ongoing. These studies will dramatically improve one's understanding of metabolic processes, bioprocessing capabilities and potential roles in health and well-being of the Lactobacilli. This review describes the current status of Lactobacillus genome sequence projects, highlights the major findings and summarizes functional genomics or comparative genomics studies. The genomic basis for the unusual diversity of this genus is discussed, and the potential for comparative genomics to rigorously extend phylogenetic analysis of the Lactobacilli is described.
  - DOI 10.1111/j.1574-6968.2006.00596.x
DA  - 2007/04
ER  - 
@article{V43336221,
   = {Claesson,  MJ and van Sinderen,  D and O'Toole,  PW },
   = {2007},
   = {April},
   = {Fems Microbiology Letters},
   = {The genus Lactobacillus - a genomic basis for understanding its diversity},
   = {Validated},
   = {()},
   = {Lactobacillus lactobacilli genomics genome sequencing phylogenetic diversity LACTIC-ACID BACTERIA ACIDOPHILUS NCFM FUNCTIONAL-ANALYSIS JOHNSONII NCC-533 FUTURE-PROSPECTS SALIVARIUS PLANTARUM SEQUENCE PROBIOTICS SAKEI},
   = {269},
  pages = {22--28},
   = {{The genus Lactobacillus is a diverse group that includes many species used in food production and preservation. Some lactobacilli are considered probiotic, conferring health benefits upon the host. The heterogeneity of this genus poses challenges and opportunities when characterizing or exploiting individual strains. To date, 10 Lactobacillus genome sequences have been published, and at least 11 more sequencing projects are ongoing. These studies will dramatically improve one's understanding of metabolic processes, bioprocessing capabilities and potential roles in health and well-being of the Lactobacilli. This review describes the current status of Lactobacillus genome sequence projects, highlights the major findings and summarizes functional genomics or comparative genomics studies. The genomic basis for the unusual diversity of this genus is discussed, and the potential for comparative genomics to rigorously extend phylogenetic analysis of the Lactobacilli is described.}},
   = {DOI 10.1111/j.1574-6968.2006.00596.x},
  source = {IRIS}
}
AUTHORSClaesson, MJ,van Sinderen, D,O'Toole, PW
YEAR2007
MONTHApril
JOURNAL_CODEFems Microbiology Letters
TITLEThe genus Lactobacillus - a genomic basis for understanding its diversity
STATUSValidated
TIMES_CITED()
SEARCH_KEYWORDLactobacillus lactobacilli genomics genome sequencing phylogenetic diversity LACTIC-ACID BACTERIA ACIDOPHILUS NCFM FUNCTIONAL-ANALYSIS JOHNSONII NCC-533 FUTURE-PROSPECTS SALIVARIUS PLANTARUM SEQUENCE PROBIOTICS SAKEI
VOLUME269
ISSUE
START_PAGE22
END_PAGE28
ABSTRACTThe genus Lactobacillus is a diverse group that includes many species used in food production and preservation. Some lactobacilli are considered probiotic, conferring health benefits upon the host. The heterogeneity of this genus poses challenges and opportunities when characterizing or exploiting individual strains. To date, 10 Lactobacillus genome sequences have been published, and at least 11 more sequencing projects are ongoing. These studies will dramatically improve one's understanding of metabolic processes, bioprocessing capabilities and potential roles in health and well-being of the Lactobacilli. This review describes the current status of Lactobacillus genome sequence projects, highlights the major findings and summarizes functional genomics or comparative genomics studies. The genomic basis for the unusual diversity of this genus is discussed, and the potential for comparative genomics to rigorously extend phylogenetic analysis of the Lactobacilli is described.
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ISBN_ISSN
EDITION
URL
DOI_LINKDOI 10.1111/j.1574-6968.2006.00596.x
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