TY  - JOUR
  - Milner, SE,Brunton, NP,Jones, PW,O'Brien, NM,Collins, SG,Maguire, AR
  - 2011
  - January
  - Bioactivities of Glycoalkaloids and Their Aglycones from Solanum Species
  - Validated
  - ()
  - glycoalkaloids structure-activity relationship anticancer aglycones synergism COLORADO POTATO BEETLE STEROIDAL ALKALOID GLYCOSIDES PERFORMANCE LIQUID-CHROMATOGRAPHY TANDEM MASS-SPECTROMETRY BREAST-CANCER CELLS DENSITY LIPOPROTEIN UPTAKE ALPHA-TOMATINE CONTENT MAGNETIC-RESONANCE-SPECTROSCOPY LEPTINOTARSA-DECEMLINEATA SAY SOLAMARGINE INDUCES APOPTOSIS
  - 3454
  - 3484
  - Potatoes, tomatoes, and aubergines are all species of the Solanum genus and contain a vast array of secondary metabolites including calystegine alkaloids, phenolic compounds, lectins, and glycoalkaloids. Glycoalkaloids have been the subject of many literature papers, occur widely in the human diet, and are known to induce toxicity. Therefore, from a food safety perspective further information is required regarding their analysis, toxicity, and bioavailability. This is especially important in crop cultivars derived from wild species to prevent glycoalkaloid-induced toxicity. A comprehensive review of the bioactivity of glycoalkaloids and their aglycones of the Solanum species, particularly focused on comparison of their bioactivities including their anticancer, anticholesterol, antimicrobial, anti-inflammatory, antinociceptive, and antipyretic effects, toxicity, and synergism of action of the principal Solanum glycoalkaloids, correlated to differences of their individual molecular structures is presented.
  - DOI 10.1021/jf200439q
DA  - 2011/01
ER  - 

@article{V160956977,
   = {Milner,  SE and Brunton,  NP and Jones,  PW and O'Brien,  NM and Collins,  SG and Maguire,  AR },
   = {2011},
   = {January},
   = {Bioactivities of Glycoalkaloids and Their Aglycones from Solanum Species},
   = {Validated},
   = {()},
   = {glycoalkaloids structure-activity relationship anticancer aglycones synergism COLORADO POTATO BEETLE STEROIDAL ALKALOID GLYCOSIDES PERFORMANCE LIQUID-CHROMATOGRAPHY TANDEM MASS-SPECTROMETRY BREAST-CANCER CELLS DENSITY LIPOPROTEIN UPTAKE ALPHA-TOMATINE CONTENT MAGNETIC-RESONANCE-SPECTROSCOPY LEPTINOTARSA-DECEMLINEATA SAY SOLAMARGINE INDUCES APOPTOSIS},
  pages = {3454--3484},
   = {{Potatoes, tomatoes, and aubergines are all species of the Solanum genus and contain a vast array of secondary metabolites including calystegine alkaloids, phenolic compounds, lectins, and glycoalkaloids. Glycoalkaloids have been the subject of many literature papers, occur widely in the human diet, and are known to induce toxicity. Therefore, from a food safety perspective further information is required regarding their analysis, toxicity, and bioavailability. This is especially important in crop cultivars derived from wild species to prevent glycoalkaloid-induced toxicity. A comprehensive review of the bioactivity of glycoalkaloids and their aglycones of the Solanum species, particularly focused on comparison of their bioactivities including their anticancer, anticholesterol, antimicrobial, anti-inflammatory, antinociceptive, and antipyretic effects, toxicity, and synergism of action of the principal Solanum glycoalkaloids, correlated to differences of their individual molecular structures is presented.}},
   = {DOI 10.1021/jf200439q},
  source = {IRIS}
}