TY  - JOUR
  - Deasy, RE,O'Riordan, N,Maguire, AR
  - 2014
  - June
  - Catalysts
  - Baker's Yeast Mediated Reduction of 2-Acetyl-3-methyl Sulfolane
  - Validated
  - WOS: 4 ()
  - baker's yeast (Saccharomyces cerevisiae) biocatalysis asymmetric reduction chiral alcohol sulfolane HIV-1 PROTEASE INHIBITORS ASYMMETRIC REDUCTION STEREOCHEMICAL CONTROL CYCLIC SULFONES 3-OXO ESTERS
  - 4
  - 186
  - 195
  - The baker's yeast mediated reduction of 2-acetyl-3-methyl sulfolane 1 to provide the corresponding alcohol 2 is described. Excellent efficiency and enantioselectivity (>98% ee) has been achieved under these mild environmentally benign reaction conditions. In direct contrast, the chemical reduction of 1 proceeds with poor yield (<= 25%) and diastereocontrol.
  - 10.3390/catal4020186
DA  - 2014/06
ER  - 

@article{V271356249,
   = {Deasy,  RE and O'Riordan,  N and Maguire,  AR },
   = {2014},
   = {June},
   = {Catalysts},
   = {Baker's Yeast Mediated Reduction of 2-Acetyl-3-methyl Sulfolane},
   = {Validated},
   = {WOS: 4 ()},
   = {baker's yeast (Saccharomyces cerevisiae) biocatalysis asymmetric reduction chiral alcohol sulfolane HIV-1 PROTEASE INHIBITORS ASYMMETRIC REDUCTION STEREOCHEMICAL CONTROL CYCLIC SULFONES 3-OXO ESTERS},
   = {4},
  pages = {186--195},
   = {{The baker's yeast mediated reduction of 2-acetyl-3-methyl sulfolane 1 to provide the corresponding alcohol 2 is described. Excellent efficiency and enantioselectivity (>98% ee) has been achieved under these mild environmentally benign reaction conditions. In direct contrast, the chemical reduction of 1 proceeds with poor yield (<= 25%) and diastereocontrol.}},
   = {10.3390/catal4020186},
  source = {IRIS}
}