Asymmetric 1,3-dipolar cycloadditions of acrylamides.

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TY  - JOUR
  - Kissane, M; Maguire, AR
  - 2010
  - February
  - Chemical Society Reviews
  - Asymmetric 1,3-dipolar cycloadditions of acrylamides.
  - Validated
  - ()
  - 39
  - 2
  - 845
  - 883
  - This critical review, which is relevant to researchers in synthetic organic chemistry, focuses on asymmetric 1,3-dipolar cycloadditions with acrylamides. The use of chiral acrylamides as dipolarophiles leads to high levels of stereocontrol, due to conformational constraint in the acrylamides. Employment of chiral tertiary acrylamides containing nitrogen heterocycles is particularly effective in controlling the stereoselectivity. Following a general overview of 1,3-dipolar cycloadditions, the main body of the review focuses on asymmetric 1,3-dipolar cycloadditions of acrylamides with nitrile oxides, nitrones, diazoalkanes and azomethine ylides, with particular emphasis on the rationale for the observed stereocontrol (215 references).
  - 10.1039/b909358n
DA  - 2010/02
ER  - 
@article{V5956736,
   = {Kissane, M and  Maguire, AR},
   = {2010},
   = {February},
   = {Chemical Society Reviews},
   = {Asymmetric 1,3-dipolar cycloadditions of acrylamides.},
   = {Validated},
   = {()},
   = {39},
   = {2},
  pages = {845--883},
   = {{This critical review, which is relevant to researchers in synthetic organic chemistry, focuses on asymmetric 1,3-dipolar cycloadditions with acrylamides. The use of chiral acrylamides as dipolarophiles leads to high levels of stereocontrol, due to conformational constraint in the acrylamides. Employment of chiral tertiary acrylamides containing nitrogen heterocycles is particularly effective in controlling the stereoselectivity. Following a general overview of 1,3-dipolar cycloadditions, the main body of the review focuses on asymmetric 1,3-dipolar cycloadditions of acrylamides with nitrile oxides, nitrones, diazoalkanes and azomethine ylides, with particular emphasis on the rationale for the observed stereocontrol (215 references).}},
   = {10.1039/b909358n},
  source = {IRIS}
}
AUTHORSKissane, M; Maguire, AR
YEAR2010
MONTHFebruary
JOURNAL_CODEChemical Society Reviews
TITLEAsymmetric 1,3-dipolar cycloadditions of acrylamides.
STATUSValidated
TIMES_CITED()
SEARCH_KEYWORD
VOLUME39
ISSUE2
START_PAGE845
END_PAGE883
ABSTRACTThis critical review, which is relevant to researchers in synthetic organic chemistry, focuses on asymmetric 1,3-dipolar cycloadditions with acrylamides. The use of chiral acrylamides as dipolarophiles leads to high levels of stereocontrol, due to conformational constraint in the acrylamides. Employment of chiral tertiary acrylamides containing nitrogen heterocycles is particularly effective in controlling the stereoselectivity. Following a general overview of 1,3-dipolar cycloadditions, the main body of the review focuses on asymmetric 1,3-dipolar cycloadditions of acrylamides with nitrile oxides, nitrones, diazoalkanes and azomethine ylides, with particular emphasis on the rationale for the observed stereocontrol (215 references).
PUBLISHER_LOCATION
ISBN_ISSN
EDITION
URL
DOI_LINK10.1039/b909358n
FUNDING_BODY
GRANT_DETAILS