Personal profile
Biography
EDUCATION: 1997 - Ph.D. (Biochemistry and Immunology), Moscow State University, Russia. Thesis title: "Diagnostics of C. trachomatis by PCR and evaluation of the parameters of the immune and interferon status in urogenital chlamydiosis". 1992 - M.Sc. (Biology), Moscow State University, Russia. Thesis title: "Development of the procedure of diagnostics of herpes simplex virus and chlamydiosis in clinical samples using DNA-hybridization and PCR". EMPLOYMENT: 2025-current: Senior Technical Officer, School of Pharmacy, UCC 2023-2025: Technical Officer, iEd Hub and School of Pharmacy, UCC 2022-2023: Technical Officer, School of Biochemistry and Cell Biology, UCC 2013-2022: Research Support Officer, Laboratory of Biophysical Analysis, School of Biochemistry and Cell Biology, UCC 2008–2013: Senior Postdoctoral Researcher, Laboratory of Biophysical Analysis, Biochemistry Department, UCC 2006–2008: Postdoctoral Researcher, Laboratory of Biophysical Analysis, Biochemistry Department, UCC 2004–2006: Postdoctoral Researcher, Mol. Cell. Biol. Laboratory, Biochemistry Department, University College Cork (UCC), Cork, Ireland 2003–2004: Postdoctoral Researcher, Institute of Physiology, Otto-von-Guericke University, Magdeburg, Germany 1996–2003: Postdoctoral Researcher, Research Centre for Obstetrics, Gynaecology and Perinatology, Moscow, Russia
Research Interests
- Monoclonal antibody production, purification and characterisation - Cell-based antibody potency assays - Mitochondrial function - Cell metabolism and bioenergetics in normoxia and hypoxia - Calcium signalling - Cancer cell metabolism, effects of oncometabolites of mitochondrial function and epigenetics Ischemia, - HIF signalling, HIF-independent responses to hypoxia and metabolic stress (APMK, translation remodelling) - Development of phosphorescence-based techniques for O2 imaging in cells, spheroids and living tissues - Monitoring and modelling of cell oxygenation and O2 gradients in (patho)-physiological conditions - Confocal and 2-photon fluorescent microscopy, live cell / tissue imaging
Teaching Activities
My teaching skills and interests include: - Designing, delivering and examining classes for Industrial Pharmaceutical Sciences, Operations and Management, MSc students - Designing and supervising MRes student projects in Industrial Pharmaceutics- Delivering classes and workshops for undergraduate Biochemistry students- Supervising 4th year, MSc, MRes and PhD student projects in Biochemistry, Chemistry of Pharmaceutical Compounds, Genetics and Biotechnology- Delivering training to researchers from the Schools of Pharmacy, Biochemistry & Cell Biology, and Pharmacology in tissue culture, microscopy, chromatography, electrophoresis, FACS, and other techniques- Teaching a lecture module ‘Cell and Molecular Biology’ for MSc students - Serving as an external examiner for MRes projects
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being -
SDG 4 Quality Education -
SDG 9 Industry, Innovation, and Infrastructure
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Comparative analysis of common potency assays for assessing human TNF-alpha neutralising antibodies
Pradeep, R., Zhdanov, A. & Allen, E., Feb 2026, In: Analytical Biochemistry.Research output: Contribution to journal › Article › peer-review
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Hybrid Oxygen-Sensing Bio-Scaffolds for 3D Micro-Tissue Models
Li, L., Zhdanov, A. V. & Papkovsky, D. B., 14 Feb 2026, In: Biosensors.Research output: Contribution to journal › Article › peer-review
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Common cell lysis procedures distort ribosome profiling analyses of gene expression
O’Connell, A., Fedorova, A. D., O’Connor, P. B. F., Zhdanov, A. V., Baranov, P. V., Loughran, G. & Andreev, D. E., Dec 2025, In: Genome Biology. 26, 1, 241.Research output: Contribution to journal › Article › peer-review
Open Access -
Optical sensor-based systems for the analysis of cell metabolism and bioenergetics
Li, L., Zhdanov, A. V. & Papkovsky, D. B., 15 Apr 2025, In: Sensors and Actuators B: Chemical. 429, 137303.Research output: Contribution to journal › Review article › peer-review
Open Access -
The mood stabilizers lithium and valproate disrupt hepatic and intestinal farnesoid X receptor signalling and increase bile synthesis in the rat
Cussotto, S., Golubeva, A. V., Gallardo, A. L., Bastiaanssen, T. F. S., Zhdanov, A. V., Moloney, G. M., Scaife, C., English, J. A., Joyce, S. A., Dinan, T. G. & Cryan, J. F., 1 Sep 2025, In: Experimental Physiology. 110, 9, p. 1233-1253 21 p.Research output: Contribution to journal › Article › peer-review
Open Access
Activities
- 1 Invited talk
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An imaging method to analyse o2 distribution in live neurospheres.
Dmitriev, R. I. (Speaker), Zhdanov, A. (Speaker), Nolan, Y. (Speaker) & Papkovsky, D. (Speaker)
2013Activity: Talk or presentation › Invited talk
Press/Media
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Findings from University College Cork Reveals New Findings on Biotechnology (Optical Sensor-based Systems for the Analysis of Cell Metabolism and Bioenergetics)
21/04/25
1 item of Media coverage
Press/Media