Personal profile
Biography
Dr. Cian McCafferty is a lecturer and principal investigator at University College Cork, working in the department of Anatomy & Neuroscience. He graduated from UCC with a B.Sc. (Hons) in Neuroscience in 2010, and from Cardiff University with a Ph.D. in experimental electrophysiology of epilepsy in 2014. For his doctoral research, Dr. McCafferty investigated the activity of thalamic neurons during absence seizures in a rat model, and the contributions of thalamic T-type calcium channels to the electrographical and behavioural components of the seizures. After a year of postdoctoral research in Cardiff University, Dr. McCafferty pursued an Epilepsy Foundation postdoctoral fellowship in Yale University. He expanded this initial fellowship into 4 years of postdoctoral research at Yale into neuronal and network mechanism of absence seizure behavioural severity, researching the hemodynamic and electrophysiological changes in the cerebral cortex associated with the behavioural severity of experimental absence seizures. Dr. McCafferty's current research at UCC focuses on the electroencephalography of epilepsy and migraine.
Research Interests
Dr. McCafferty's research interests focus on the information that is carried in electroencephalographic (EEG) signals about seizures and migraines, and how that information can be used by people with epilepsy and migraineurs. In epilepsy research, he is investigating the priorities of people with epilepsy in seizure forecasting devices and how these can be addressed using existing seizure prediction algorithms and repositories of EEG recordings. In migraine research, he investigates how physiological variables (including EEG features, cardiovascular features, and activity) change over the course of the migraine cycle and is interested in the neurophysiological mechanisms that cause migraine headaches.
Teaching Activities
Dr. McCafferty is interested in the application of backward design and active learning principles to achieve goal-oriented learning: the identification of graduate skillsets, attributes, and goals, and the construction of teaching and learning materials and methods to best bring students towards them. His teaching in the Neuroscience (CK402) and Medical and Health Sciences (CK707) programs aims to equip students to apply broad scientific principles to their lives and careers, focusing on the interpretation of scientific data in its various forms as well as the design of experiments to address outstanding scientific questions and the effective presentation of the ensuing data. Dr. McCafferty also teaches Neuroscience students in his specific areas of research interest, including epilepsy, consciousness, and awareness.
UCC Futures (primary)
- Future Ageing and Brain Science
PhD Supervision
- Available for PhD supervision
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
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Collaborations and top research areas from the last five years
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Classifying seizure generation mechanisms: A critical transitions framework
Flynn, A., McCafferty, C., Lehnertz, K., David, F., Crunelli, V., Marnane, W. P. & Wieczorek, S., 25 Nov 2025, arXiv, p. 1-42, 42 p.Research output: Working paper/Preprint › Preprint
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Immersive Virtual Reality Education for Electroencephalography Interpretation
Creed, A., Murphy, D., McCafferty, C., Chan, J., Quintana, S. G., Temko, A., Popovici, E. & Factor, A., 21 Jun 2025.Research output: Contribution to conference › Paper › peer-review
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Robust Hippocampal Synaptic Plasticity Despite Gut Microbiota Depletion in Adult Mice
Collins, M., Darch, H., Olavarría‐Ramírez, L., McCafferty, C., O'Riordan, K. & Cryan, J., Dec 2025, In: European Journal of Neuroscience.Research output: Contribution to journal › Article › peer-review
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WONOEP XVII appraisal: Targeting network excitability beyond the synapse -Neurotransmitter, ionic, and electro -diffusions
Magloire, V., de Curtis, M., Noebels, J., Huberfeld, G., Suffczynski, P., Gnatkovsky, V., Tyurikova, O., Durand, D., Henshall, D. C. & McCafferty, C., 2025, (Accepted/In press) In: Epilepsia.Research output: Contribution to journal › Review article › peer-review
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Neuronal rhythmicity and cortical arousal in a mouse model of absence epilepsy
Khan, W., Chopra, S., Zheng, X., Liu, S., Paszkowski, P., Valcarce-Aspegren, M., Sieu, L. A., Mcgill, S., Mccafferty, C. & Blumenfeld, H., Nov 2024, In: Experimental Neurology. 381, 114925.Research output: Contribution to journal › Article › peer-review
Open Access
Press/Media
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Brooke Shields had a grand mal seizure – here’s what you need to know about the condition
6/11/23
1 item of Media coverage
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Brooke Shields had a grand mal seizure – here’s what you need to know about the condition
4/11/23
1 item of Media coverage
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Study identifies neuronal basis of impaired consciousness in 'absence' epilepsy
23/03/23
1 item of Media coverage
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New UCC research into seizures could "transform" lives of people with epilepsy
13/01/23
1 item of Media coverage
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