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1992 …2026

Research activity per year

Personal profile

Biography

David Clarke graduated with a B.Sc in Biotechnology from Dublin City University in 1989. From here he went to the National University of Ireland in Maynooth to undertake a PhD in Microbiology, graduating in 1993. He then traveled to France where he was awarded an International Traveling Prize Fellowship by the Wellcome Trust to undertake post-doctoral research in the laboratory of Professor Barry Holland who was based at the Institut de Genetique et Microbiologie, Universite Paris-Sud. In September 1998 David briefly returned to the Department of Biology at NUI Maynooth before joining the faculty of the Department of Biology and Biochemistry at the University of Bath, UK as a Lecturer in January 2000. He returned to Ireland in February 2007 and he is a Professor in the School of Microbiology at UCC. Prof Clarke is currently Head of the School of Microbiology, Director of the BSc Biotechnology programme and he is a Funded Investigator in APC Microbiome Ireland (http://apc.ucc.ie).

Research Interests

My research is interested in understanding the molecular biology of bacteria-host interactions i.e. symbiosis. Recent studies have shown that the complex interactions between bacteria and hosts (such as humans) are essential for the well-being of the host. However these interactions when inappropriate can also cause disease. Research in my laboratory is focused on understanding the molecular consequences associated with the change from beneficial bacteria to pathogen. To address this question we are using a number of model bacterial species including Escherichia coli and Bacteroides (important inhabitants of the human gut) and Photorhabdus (a bacterium that inhabits the gut of soil-dwelling nematodes and is a potent pathogen of insects).

Teaching Activities

Modules currently coordinating: BT1001/BT2001 "Introduction to Biotechnology"BT3001 "Literature review for BSc Biotechnology students"BT4001 "Work placement module for BSc Biotechnology students"BT4005 "Pharmaceutical and Medical Devices Microbiology"MB6009 "Introduction to Microbiology" PhD students currently supervised: Fairouz Gzara (2020-) SupervisorEvelyn Blake (2023-) Co-supervisorEmmet Conroy (2024-) Co-supervisorRoberto Faggiani (2024-) Co-supervisor

UCC Futures (primary)

  • Food, Microbiome and Health

Other research affiliations

  • FSRC - Future of Sustainable Fermentation (SUSFERM)

PhD Supervision

  • Available for PhD supervision

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