Personal profile
Biography
Eileen obtained her PhD in Nutritional Sciences from UCC under the supervision of Professor Nora O’Brien. She spent a year here as a postdoctoral scientist and in 2008, after moving to Australia, took up a post at the Centre for Drug Candidate Optimization (CDCO) based within Monash University. Here she spent several years working as a research officer with a focus on in vitro drug metabolism and on mass spectrometry (MS) based identification and structural elucidation of drug metabolites. In December 2014, she accepted a postdoctoral position with Professor Gavin Reid (Professor of Bioanalytical Chemistry) at the Bio21 Institute of Molecular Sciences & Biotechnology, University of Melbourne. Here her research was primarily focused on MS based lipid analysis (lipidomics), specifically on the development of novel MS based strategies for analysis of complex lipids and bioactive lipid mediators as well as the application of these methods toward understanding the role of lipids in the onset and progression of disease. In 2018, Eileen was awarded an APEX fellowship at APC Microbiome Ireland and thereafter a prestigious Marie Skłodowska-Curie Individual Fellowship (IF) in February 2020. She joined the School of Food and Nutritional Sciences, as lectrurer and PI in Nutrition, in November 2023.
Research Interests
Eileen’s research interests include nutritional biochemistry, bioactives (particularly bioactive lipids - dietary, mammalian, bacterial), biomarker discovery through lipidomics, metabolic pathways, food contaminants & toxicology
Research Grants
Active:
EPA Research Grant 2024: Lead PI: €639,700 on ‘DIetary exposSure and Risk to hEalth of Per- and poly-fluroAlkyl substances: an IRish perspective (DISREPAIR)’. March 2025 to February 2029.
SFI-IRC Pathways Programme Grant: 2023: Lead PI: €592,218 on ‘The role of Bacterial Lipids in the micrObe-hOst Dialogue (BLOOD)’. September 2024 to August 2028.
Finished:
H2020- Marie Skłodowska-Curie (MSCA) Individual Fellowships -2019: Lead: €196,590 on ‘The role of microbial Oxylipins in the MIcrobe-hosT dialogue (OMIT)’
H2020- MSCA-APC cofund (APEX)-2018: Lead: €190,000 on ‘Unravelling the metabolic aetiology of Inflammatory Bowel Disease (IBD) via lipidome, metabolome and microbiome multivariate analyses (IBD-ome)’
Current PhD Students
James Murphy (Lead Supervisor)
Emmet Conroy (Lead Supervisor)
Maeve Corkery (Lead Supervisor)
Leia Joanne Wilmot (Co-supervisor)
Teaching Activities
NT3002: Food Toxicology, module co-ordinator
NT4002: Advanced Nutrient Metabolism
UCC Futures (primary)
- Food, Microbiome and Health
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 2 Zero Hunger
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SDG 3 Good Health and Well-being
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SDG 4 Quality Education
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SDG 12 Responsible Consumption and Production
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SDG 15 Life on Land
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Collaborations and top research areas from the last five years
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Lipidomic Analysis Reveals Differences in Bacteroides Species Driven Largely by Plasmalogens, Glycerophosphoinositols and Certain Sphingolipids
Ryan, E., Gonzalez Pastor, B., Gethings, L. A., Clarke, D. J. & Joyce, S. A., Mar 2023, In: Metabolites. 13, 3, 18 p., 360.Research output: Contribution to journal › Article › peer-review
Open Access -
Membrane lipids from gut microbiome-associated bacteria as structural and signalling molecules
Ryan, E., Joyce, S. A. & Clarke, D. J., Mar 2023, In: Microbiology (United Kingdom). 169, 3, 13 p., 001315.Research output: Contribution to journal › Review article › peer-review
Open Access -
Metabolic, Pharmacokinetic, and Activity Profile of the Liver Stage Antimalarial (RC-12)
Dong, Y., Sonawane, Y., Maher, S. P., Zeeman, A. M., Chaumeau, V., Vantaux, A., Cooper, C. A., Chiu, F. C. K., Ryan, E., McLaren, J., Chen, G., Wittlin, S., Witkowski, B., Nosten, F., Sriraghavan, K., Kyle, D. E., Kocken, C. H. M., Charman, S. A. & Vennerstrom, J. L., 12 Apr 2022, In: ACS Omega. 7, 14, p. 12401-12411 11 p.Research output: Contribution to journal › Article › peer-review
Open Access -
An in vitro toolbox to accelerate anti-malarial drug discovery and development
Charman, S. A., Andreu, A., Barker, H., Blundell, S., Campbell, A., Campbell, M., Chen, G., Chiu, F. C. K., Crighton, E., Katneni, K., Morizzi, J., Patil, R., Pham, T., Ryan, E., Saunders, J., Shackleford, D. M., White, K. L., Almond, L., Dickins, M. & Smith, D. A. & 3 others, , 2 Jan 2020, In: Malaria Journal. 19, 1, 1.Research output: Contribution to journal › Article › peer-review
Open Access -
Cytokine and lipid metabolome effects of low-dose acetylsalicylic acid in critically ill patients with systemic inflammation: a pilot, feasibility, multicentre, randomised, placebo-controlled trial
Cioccari, L., Luethi, N., Duong, T., Ryan, E., Cutuli, S. L., Lloyd-Donald, P., Eastwood, G. M., Peck, L., Young, H., Vaara, S. T., French, C. J., Orford, N., Dwivedi, J., Lankadeva, Y. R., Bailey, M., Reid, G. E. & Bellomo, R., Sep 2020, In: Critical Care and Resuscitation. 22, 3, p. 227-236 10 p.Research output: Contribution to journal › Article › peer-review
Activities
- 12 Oral presentation
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The effect of lutein, sesamol, ellagic acid and olive leaf extract on colour and lipid stability in model porcine muscle systems
Hayes, J. (Speaker), Allen, P. (Speaker), Stepanyan, V. (Speaker), Ryan, E. (Speaker), O'Grady, M. N. (Speaker), Kerry, J. (Speaker) & O'Brien, N. (Speaker)
2008Activity: Talk or presentation › Oral presentation
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Colour and lipid oxidation in raw and cooked beef patties containing added plant extracts and stored in modified atmosphere packs
McGovern, L. (Speaker), O'Grady, M. N. (Speaker), Ryan, E. (Speaker), O'Brien, N. (Speaker) & Kerry, J. (Speaker)
4 Sep 2007Activity: Talk or presentation › Oral presentation
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The effect of plant extracts on lipid oxidation and oxymyoglobin oxidation in beef muscle model systems
McGovern, L. (Speaker), O'Grady, M. N. (Speaker), Aherne-Bruce, S. A. (Speaker), Ryan, E. (Speaker), O'Brien, N. (Speaker) & Kerry, J. (Speaker)
1 Sep 2007Activity: Talk or presentation › Oral presentation
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Phytosterol, tocopherol and squalene content of selected nuts, seeds, legumes and grains
Ryan, E. (Speaker), Galvin, K. (Speaker), O’Connor, T. P. (Speaker) & O'Brien, N. (Speaker)
1 Aug 2007Activity: Talk or presentation › Oral presentation
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The effect of b-sitosterol on caco-2 cellular uptake of various carotenoids and fatty acids
Ryan, E. (Speaker) & O'Brien, N. (Speaker)
2006Activity: Talk or presentation › Oral presentation
Press/Media
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-University College Cork: UCC researchers awarded EUR2.3m for new research to address climate and environmental challenges
Ryan, E., Cryan, J. F., Boylan, G., Hennessy, A., Bose, A., Kiely, M., Dunphy, N. & Vahid, A.
21/02/25
2 items of Media coverage
Press/Media
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EPA announces funding of €14.5m for new research to address climate and environmental challenges
Ryan, E., Bose, A. & Dunphy, N.
20/02/25
1 item of Media coverage
Press/Media
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20 Feb 2025 UCC researchers awarded €2.3m for new research to address climate and environmental challenges
Ryan, E., Cryan, J. F., Boylan, G., Hennessy, A., Bose, A., Kiely, M., Dunphy, N. & Vahid, A.
20/02/25
1 item of Media coverage
Press/Media
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-University College Cork : EUR2.9m funding awarded to UCC early career researchers in SFI-IRC Pathway Programme awards
Ryan, E., Cryan, J. F., Nagpal, J., Imbrogno, A., Kundu, C. & Jones, D.
12/07/24
2 items of Media coverage
Press/Media
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€2.9m funding awarded to UCC early career researchers in SFI-IRC Pathway Programme awards
Ryan, E., Cryan, J. F., Nagpal, J., Imbrogno, A., Kundu, C. & Jones, D.
11/07/24
1 item of Media coverage
Press/Media