Research output per year
Research output per year
Personal profile
Biography
Gerard Clarke is Professor of Neurobehavioural Science in the Department of Psychiatry and Neurobehavioural Science and a Principal Investigator in APC Microbiome Ireland at University College Cork. His research interests include the impact of the gut microbiome on brain and behaviour across the life span, microbial regulation of tryptophan metabolism and translational biomarkers of stress-related neuropsychiatric disorders. Gerard holds a BSc (Hons) degree in Chemistry, an MSc degree in Neuropharmacology (1999 and 2001; Both from NUI, Galway) and a PhD degree (2009) in Neurogastroenterology (Department of Psychiatry, UCC). He was included in Clarivate Analytics Web of Science Group Highly Cited Researchers list for 6 consecutive years from 2019-2024. He has recently co-authored a book titled Microbiota Brain Axis: A Neuroscience Primer which provides a framework for understanding microbial regulation of brain function and behaviour.
UCC Futures (primary)
- Food, Microbiome and Health
PhD Supervision
- Available for PhD supervision
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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A manifesto for universal healthcare: reconstituting primary care through digital innovation, microbial technologies and empowered citizenship
Timmis, K., Clarke, G., Colom, M. F., Karahan, Z. C. & Armstrong, R., 20 Apr 2026, In: Microb. Biotechnol.. 19, 4, 28 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
Bifidobacterium longum and prebiotic interventions restore early-life high-fat/high-sugar diet-induced alterations in feeding behavior in adult mice
Cuesta-Marti, C., Ponce-España, E., Uhlig, F., Stoltenborg, I., Wasiewska, L. A., Kareem, L., Hedayatpour, D., Olavarría-Ramírez, L., Rosell-Cardona, C., Bastiaanssen, T. F. S., Tofani, G. S. S., Valderrama, B., Vlckova, K., Dickson, S. L., Lavelle, A., Stanton, C., Ross, R. P., Cryan, J. F., Dinan, T. G. & Clarke, G. & 2 others, , 24 Feb 2026, In: Nature Communications.Research output: Contribution to journal › Article › peer-review
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Correction: Microbiota is essential for social development in the mouse
Desbonnet, L., Clarke, G., Shanahan, F., Dinan, T. G. & Cryan, J. F., 9 Feb 2026, (E-pub ahead of print) In: Molecular Psychiatry.Research output: Contribution to journal › Article › peer-review
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Development and Validation of a Food Frequency Questionnaire to Assess Fermented Food Consumption in Adults
Ferri, A., Schneider, E., Lucey, A., Hennessy, Á., Cotter, P. D., Balasubramanian, R., Clarke, G. & Cryan, J. F., Feb 2026, In: Journal of Human Nutrition and Dietetics.Research output: Contribution to journal › Article › peer-review
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Early-life microbiota disruption-induced deficits in the social brain are sensitive to diet
Ratsika, A., Bergmann, C. A., Valderrama, B., Bastiaanssen, T. F. S., Sharvin, B. L., Renes, I. B., Knol, J., Gunnigle, E., Clarke, G. & Cryan, J. F., 20 Mar 2026, In: iScience. 29, 3, 114968.Research output: Contribution to journal › Article › peer-review
Open Access
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Sex-specific effects of stress during puberty on antidepressant-like behaviour and monoamine neurotransmitters in adolescence and adulthood.
Harris, E. P. (Speaker), Manriques Villalobos, F. (Speaker), Clarke, G. (Speaker) & O'Leary, O. (Speaker)
6 Nov 2020Activity: Talk or presentation › Oral presentation
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Acute tryptophan depletion modulates kynurenine production: Implications for treatment of cognitive impairment in brain-gut axis disorders.
Kennedy, P. J. (Speaker), Allen, A. P. (Speaker), O'Neill, A. (Speaker), Quigley, E. M. M. (Speaker), Cryan, J. F. (Speaker), Dinan, T. (Speaker) & Clarke, G. (Speaker)
15 Nov 2014 → 19 Nov 2014Activity: Talk or presentation › Invited talk
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Whole blood microRNAs as biomarkers of treatment-resistant depression? Effects of ketamine and electroconvulsive therapy
Scott, K. A. (Speaker), Moloney, G. (Speaker), Naughton, M. (Speaker), O'Connor, R. M. (Speaker), McLoughlin, D. M. (Speaker), Dowling, J. (Speaker), Shorten, G. (Speaker), Walsh, A. (Speaker), Scott, L. (Speaker), Ismail, F. (Speaker), Clarke, G. (Speaker), Dinan, T. (Speaker) & Cryan, J. F. (Speaker)
15 Nov 2014 → 19 Nov 2014Activity: Talk or presentation › Invited talk
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Rapid antidepressant response to ketamine in treatment-resistant depression is not dependent on normalising kynurenine pathway metabolism
Clarke, G. (Speaker), Naughton, M. (Speaker), O'Shea, R. (Speaker), Dowling, J. (Speaker), Walsh, A. (Speaker), Ismail, F. (Speaker), Shorten, G. (Speaker), Scott, L. (Speaker), Cryan, J. F. (Speaker) & Dinan, T. (Speaker)
15 Nov 2014 → 19 Nov 2014Activity: Talk or presentation › Invited talk
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A delayed brain-derived neurotrophic factor response to ketamine infusion: Implications for rapid symptom improvements in treatment-resistant depression
Allen, A. P. (Speaker), Naughton, M. (Speaker), Clarke, G. (Speaker), O'Shea, R. (Speaker), Dowling, J. (Speaker), Walsh, A. (Speaker), Ismail, F. (Speaker), Shorten, G. (Speaker), Scott, L. (Speaker), Cryan, J. F. (Speaker) & Dinan, T. (Speaker)
15 Nov 2014 → 19 Nov 2014Activity: Talk or presentation › Invited talk
Press/Media
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Scientists discover how coffee interacts with the gut microbiome to affect the human brain
Clarke, G., Cryan, J. F., O'Riordan, K. J., Schneider, E. & Moloney, G.
2/06/26
1 item of Media coverage
Press/Media
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Feeling foggy and tired? Your gut health may be affecting your brain
11/05/26 → 19/05/26
6 items of Media coverage
Press/Media
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Scientists Tracked What Happens To The Gut After Quitting Coffee For Two Weeks
Clarke, G., Cryan, J. F. & Moloney, G.
22/04/26
1 item of Media coverage
Press/Media
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Two UCC scientists join prestigious academy of world-leading microbiologists
Ross, R. P., Clarke, G. & Cryan, J. F.
23/03/26
1 item of Media coverage
Press/Media
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Probiotics and prebiotics restore appetite control in mice raised on unhealthy diets
Ross, R. P., Schellekens, H., Clarke, G., Cryan, J. F., O'Mahony, S., Rosell Cardona, C., Lavelle, A., Uhlig, F., Wasiewska, L. & Dinan, T.
26/02/26
1 item of Media coverage
Press/Media