Personal profile
Biography
Professor John F. Cryan is Professor & Chair at the Department of Anatomy and Neuroscience in the School of Medicine, and was appointed Vice President for Research & Innovation in March 2021. He is also a Principal Investigator in the APC Microbiome Institute. He received a B.Sc. (Hons) in Biochemistry and PhD in Pharmacology from University of Galway, Ireland and was a visiting fellow at the Dept Psychiatry, University of Melbourne, Australia, which was followed by postdoctoral fellowships at the University of Pennsylvania, Philadelphia, USA and The Scripps Research Institute, La Jolla, California. He spent four years as a Group Leader in the pharmaceutical industry at the Novartis Institute for BioMedical Research in Basel Switzerland, prior to joining UCC in 2005.
Professor Cryan's current research is focused on understanding the interaction between brain, gut and microbiome and how it applies to stress, psychiatric and immune-related disorders at key time-windows across the lifespan.
He is a Senior Editor of Neuropharmacology and of Neurobiology of Stress. He is on the editorial board of a further 15 journals. He was elected a Member of the Royal Irish Academy in 2017 and has served on UCC’s Governing Body from 2015-2021.
Research Interests
- Microbiome, brain and behaviour across the lifespan
- Neurobiology of stress-related disorders including depression, anxiety, drug addiction, cognitive dysfunction and irritable bowel syndrome (IBS)
- Immune - Brain interactions
- Behavioural Pharmacology
Current PhD Students
| Student name | Supervision period |
| Brendan Sharvin | 2021-present |
| Ramya Balasubramanian | 2021-present |
| Aimone Ferri | 2022-present |
| Naomi Gavali | 2022-present |
| Hugo Blair | 2022-present |
| Alex Cergneaux | 2022-present |
| Jennifer Moreal | 2022-present |
| Melanie Depret | 2022-present |
| Ketki Mulay | 2022-present |
| Benjamin Valderrama | 2023-Present |
| Zoe Williams | 2023-present |
| Sauranil Guha | 2024-present |
| Koushika Chandrasekaran | 2024-present |
| Sena Gucer | 2024-present |
| Parul Sharma | 2025-present |
| McKenna Williams | 2025-present |
| Jade Lawless | 2025-Present |
| Kristian West | 2025-Present |
| Nishtha Mahadev Pange | 2025-Present |
| Jessica Hincks | 2025-Present |
| Cristian Mendoza Ortiz | 2026-Present |
External positions
Treasurer & Member Executive Committee, European College of Neuropsychopharmacology
2025 → …
Chair Talent Panel, Lundbeck Foundation Initiative for Integrative Psychiatric Research
2025 → …
Hagler Fellow, Texas A&M University
Sep 2024 → …
Member Scientific Advisory Board, Central Institute for Mental Health
2024 → …
Member Scientific Advisory Board, Food Research and Innovation Centre
2024 → …
Member Scientific Advisory Board, Max Planck Institute for Psychiatry
2024 → …
Member EMBL, Heidelberg Human Ecosystems Transversal Theme Expert Panel
2023 → …
Chair Talent Panel, Lundbeck Foundation Initiative for Integrative Psychiatric Research
2021 → …
Chair Scientific Advisory Panel, Weston Foundation Canada
2020 → …
UCC Futures (primary)
- Food, Microbiome and Health
Other research affiliations
- UCC Futures - Future Ageing and Brain Science
PhD Supervision
- Available for PhD supervision
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
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SDG 4 Quality Education
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SDG 9 Industry, Innovation, and Infrastructure
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SDG 17 Partnerships for the Goals
Fingerprint
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Collaborations and top research areas from the last five years
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Psychotropic Drugs and the Microbiome
Cussotto, S., Clarke, G., Dinan, T. G. & Cryan, J. F., 2021, In: Modern Trends in Psychiatry. 32, p. 113-133 21 p.Research output: Contribution to journal › Article › peer-review
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Gut microbiota regulates stress responsivity via the circadian system
Tofani, G. S. S., Leigh, S. J., Gheorghe, C. E., Bastiaanssen, T. F. S., Wilmes, L., Sen, P., Clarke, G. & Cryan, J. F., 7 Jan 2025, In: Cell Metabolism. 37, 1, p. 138-153.e5Research output: Contribution to journal › Article › peer-review
Open Access -
Correction: Microbiota is essential for social development in the mouse
Desbonnet, L., Clarke, G., Shanahan, F., Dinan, T. G. & Cryan, J. F., 9 Feb 2026, (E-pub ahead of print) In: Molecular Psychiatry.Research output: Contribution to journal › Article › peer-review
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Corrigendum to: Maternal antibiotic administration during a critical developmental window has enduring neurobehavioural effects in offspring mice
O'Connor, R., Moloney, G. M., Füllling, C., O'Riordan, K., Fitzgerald, P., Schellekens, H., Dinan, T. G. & Cryan, J. F., 28 Mar 2026, In: Behavioural Brain Research. 502, 116041.Research output: Contribution to journal › Comment/Debate
Open Access -
Hepatic tryptophan metabolism links chronic stress to liver cancer
Clarke, G., Keane, L. & Cryan, J. F., 19 Jan 2026, In: Nature Metabolism.Research output: Contribution to journal › Article › peer-review
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Gut microbiome: A key regulator of neuroinflammation & behaviour
Cryan, J. (Invited speaker)
7 Nov 2025Activity: Talk or presentation › Invited talk
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Microbiomes and Mental Health - Connecting the Dots
Cryan, J. (Keynote speaker)
29 Sep 2025Activity: Talk or presentation › Invited talk
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Bugs, Drugs & Behaviour: Microbiome as a Key Regulator of Brain Function Across the Lifespan
Cryan, J. (Keynote speaker)
17 Sep 2025Activity: Talk or presentation › Oral presentation
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Flux: The Society for Developmental Cognitive Neuroscience
Cryan, J. (Speaker)
4 Sep 2025Activity: Talk or presentation › Invited talk
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Gut feelings – Microbiome, Brain and Behaviour Across the Lifespan
Cryan, J. (Keynote speaker)
3 Sep 2025Activity: Talk or presentation › Invited talk
Prizes
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Best Publication Biological Psychiatry (Somerfeld-Ziskind Award to first author Aurelijus Burokas)
Cryan, J. (Recipient), May 2019
Prize: Honorary award
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Press/Media
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New study reveals early healthy eating shapes lifelong brain health
Schellekens, H. & Cryan, J. F.
24/02/26 → 26/02/26
7 items of Media coverage
Press/Media
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Childhood exposure to poor food can lead to lasting changes in brain function
Schellekens, H. & Cryan, J. F.
24/02/26 → 25/02/26
2 items of Media coverage
Press/Media
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New Research Shows Early Healthy Eating Influences Brain Health Across a Lifetime
Schellekens, H. & Cryan, J. F.
24/02/26
2 items of Media coverage
Press/Media
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UT Dallas’ BrainHealth Week brings brain science to the public
20/02/26
1 item of Media coverage
Press/Media
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New research aims to transform breastfeed preparation and improve outcomes from birth
Morrissey, K., Cryan, J. F., O'Flynn, B. & Menolotto, M.
12/02/26
1 item of Media coverage
Press/Media