Personal profile
Biography
Dr Kellie Dean is a Senior Lecturer and Principal Investigator in the School of Biochemistry and Cell Biology at University College Cork (UCC), Ireland. She competed a PhD in Biochemistry and Biophysics from the University of North Carolina at Chapel Hill. She was post-doctoral researcher first at the Center for Molecular Biology (ZMBH), University of Heidelberg, Germany, and later with the Howard Hughes Medical Institute at Duke University in Durham, North Carolina.
Moving to Ireland in 2005, Kellie began lecturing part-time at UCC in Medicine, Dentistry and Pharmacy programmes. In 2008, she was appointed as Training Coordinator of a Health Research Board (HRB)-funded PhD Scholars Programme in Cancer Biology. Since 2015 she has been leading a research group that is focused on understanding the roles of non-coding RNAs, RNA-binding proteins, RNA-protein complexes in cancer and other human diseases. Her other research interests include translational control, microproteins, phase separation, intrinsically disordered proteins and short linear motifs.
Internationally, Kellie is a working group co-leader in the EU COST Action TRANSLACORE (until 2026), a member of the TransCODE consortium and is a scientific advisor for the YWHAG Foundation. She is a member of the All-Ireland RNA Club, Irish and European Associations for Cancer Research, the Biochemical Society, and the RNA Society.
PhD Supervision
- Available for PhD supervision
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
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SDG 4 Quality Education
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Collaborations and top research areas from the last five years
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Condensate Formation of the Human RNA-binding Protein SMAUG1 is Controlled by its Intrinsically Disordered Regions and Interactions with 14-3-3 Proteins
Carey, O., Fehilly, J., O'Leary, E. T., O'Shea, S., Juda, K., Fitzel, R., Selvaraj, P., Burk, K., Lindsay, A. J., Young, P., Pancsa, R., Mészáros, B. & Dean, K., 1 Oct 2025, In: Journal of Molecular Biology. 437, 19, 169314.Research output: Contribution to journal › Article › peer-review
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The implication of non-AUG-initiated N-terminally extended proteoforms in cancer
Pancsa, R., Andreev, D. E. & Dean, K., 2025, In: RNA Biology. 22, 1, p. 1-18 18 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Translon: a single term for translated regions
TRANSLACORE, 1 Oct 2025, In: Nature Methods. 22, 10, p. 2002-2006 5 p.Research output: Contribution to journal › Letter › peer-review
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ClassifieR 2.0: expanding interactive gene expression-based stratification to prostate and high-grade serous ovarian cancer
McCabe, A., Quinn, G. P., Jain, S., Ó Dálaigh, M., Dean, K., Murphy, R. G. & McDade, S. S., Dec 2024, In: BMC Bioinformatics. 25, 1, 362.Research output: Contribution to journal › Article › peer-review
Open Access -
ELM-the Eukaryotic Linear Motif resource-2024 update
Kumar, M., Michael, S., Alvarado-Valverde, J., Zeke, A., Lazar, T., Glavina, J., Nagy-Kanta, E., Donagh, J. M., Kalman, Z. E., Pascarelli, S., Palopoli, N., Dobson, L., Suarez, C. F., Van Roey, K., Krystkowiak, I., Griffin, J. E., Nagpal, A., Bhardwaj, R., Diella, F. & Mészáros, B. & 5 others, , 5 Jan 2024, In: Nucleic Acids Research. 52, D1, p. D442-D455Research output: Contribution to journal › Article › peer-review
Open Access
Press/Media
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‘Science became my refuge’: From Honduras to a Nobel lab via Cork
Yensi Alejandra, F. B., Dean, K. & Tangney, M.
11/02/25
1 item of Media coverage
Press/Media
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University College Cork: Save to Favourites; Early-career researchers receive awards to address healthcare challenges
Dean, K., Cryan, J. F. & Crean, A.
4/02/25
3 items of Media coverage
Press/Media
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Early-career researchers receive awards to address healthcare challenges
Dean, K., Cryan, J. F. & Crean, A.
3/02/25
2 items of Media coverage
Press/Media
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Decoding Early Ovarian Cancer Signals: A Game-Changer in Early Detection
12/12/24
1 item of Media coverage
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Decoding early signals to catch ovarian cancer sooner; Aideen McCabe is a PhD student at University College Cork
Dean, K. & McCabe, A.
12/12/24
2 items of Media coverage
Press/Media