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Biography

Maria Sousa Gallagher is a Professor and Principal Investigator in Process & Chemical Engineering (PCE), School of Engineering & Architecture at University College Cork (UCC). With extensive experience spanning over 30 years, she serves as Academic and Principal Investigator across various institutes, focusing on food and environmental research. Prof. Sousa Gallagher’s expertise's encompass Manufacturing Competitiveness, advancing the Circular economy and Sustainable Development Goals through innovative engineering systems, integrating processing Technologies and novel materials.

Currently she is Co-Director of SUSFERM, Centre for Sustainable Fermentation and Bioprocessing Systems for Food and the Bioeconomy, and the academic vice-director for the MEngSc in Industrial Biotechnology and Biomanufacturing. She was director of the PG Diploma and Masters in Pharmaceutical and Biopharmaceutical Engineering (2016-2021), led and coordinated numerous minor research thesis, and lecturer in biopharmaceutical Engineering.

Prof. Sousa Gallagher has led and/or been involved in 30 successful competitive Research Grants, internationally, in European programmes (INTERREG-AA, ERAMIN2, FP7, CRAFT, INCO, ALFA, FAIR, AAIR), and nationally (FIRM, EI, PC, C+) and at a fundamental and applied level. Her work involved collaborative innovative projects with several international and national research groups, several international companies and the Irish industry. She was Co-PI for Pack-in-MAP® licence, and the Spin-out company with EI PC and C+ funds. She was also the coordinator and chief investigator in EU ERA‐MIN2 RecEOL, and a partner and PI, on the EU Interreg-AA SEAFOODAGE.

Research Interests

Professor Sousa-Gallagher's overarching goals have been developing sustainable engineering systems by integrating processes for the Circular economy (Biological and Technical) and building sustainable systems of tomorrow. 

Currently her research interests encompass 3 major strategic areas:

1. Manufacturing Competitiveness and Circular Economy: Quality by Design and data analyses for pharmaceutical/biopharmaceutical, food/biochemical system; Risktools and engineering aspects in food distribution, Integrative mathematical modelling of processing systems. 

2. Sustainable Environmental Technologies: Novel and efficient recycling process for composite material (tyre, printed circuit board, plastics, etc) combining pyrolysis with sink-float separation;

3. Sustainable Processing Technologies and Novel Materials : integrated processes for the circular economy; novel materials; engineering packaging design & optimisation; packaging properties needs for respiring and non-respiring products; quality and shelf-life estimation.

 

Current PhD Students

  • Professor Sousa-Gallagher is currently Academic Vice-Director for MEngSc in Industrial Biotechnology and Biomanufacturing. 
  • Director Masters and PG Diploma in Pharmaceutical & Biopharmaceutical Engineering (2016-21). Lead, coordinating Part II (Minor Research Thesis), supervised 88 industry-based MRT (60 MRT on the last 5 years).
  • Professor Sousa-Gallagher supervised to completion over 100 postgraduates students, including 15 PhDs and 101 MEngSc, and mentored 6 Post-Doctorates. Currently supervising 1 PhDs. Leading, coordinating and supervising BE Research project and ME Research Thesis in Process & Chemical Engineering (PCE). Supervised more than 100 BE Final Year Research Projects.
  • Currently supervising 1 employment-based PhD, and 3 MEngSc Research Dissertations.
  • Coordinator and Academic Mentor of Process & Chemical Engineering Industry Work Placement Programme, since 2002. Responsible for selecting and mentoring the best Process & Chemical Engineering student for the Joe Gantly Prize in Engineering. The Joe Gantly award recognises the contribution to Cork’s business community, and is awarded by Cork Chamber of Commerce to the best overall engineering student on work placement. 

 

Year

Student Name

Degree

Thesis Title

2026

Carlos Belloch Molina

PhD in Microbiology (co-supervisor)

Strategies to design bioprocesses for sustainable yeast-based production of recombinant proteins and bioproducts

2026

Cathal Gearoid Brady

ME in Process & Chemical Engineering

Optimizing Oxygen Transfer in a 15K Bioreactor: Impact of Sparger and Agitator Design on kLa and Cell Culture Performance

2026

Aoife Helen Sweetnam

ME in Process & Chemical Engineering

Evaluate the implementation of selected viral technologies for downstream process optimisation

2026

Seán Joseph Henchion

ME in Process & Chemical Engineering

Evaluate the feasibility and impacts of integrating perfusion technology into single-use bioreactors for clinical manufacturing

2026

Mark David Skuce

ME in Process & Chemical Engineering

MSD Building 8 Engineering Buffer Process Optimization Project

2026

James Wilson O’Callaghan

ME in Process & Chemical Engineering

Development of a Dashboard for Real-Time RTMS Data Visualization in Process Engineering

2025

Katie Ryan

ME in Process & Chemical Engineering

Optimising Bioprocess Performance for Higher Titre Production through Sparging and N-1 Perfusion Techniques

2025

Leah O’Regan

ME in Process & Chemical Engineering

Optimisation of process monitoring using process analytical technologies

2025

Gemma McCarthy

ME in Process & Chemical Engineering

Investigation into Foaming Formation in Perfusion Bioreactors

2025

Emily Roche

ME in Process & Chemical Engineering

High-Titre Solutions: A Comparative Study of Centrifuge Technologies in Biopharma Production

2025

Eoghan McCarthy

ME in Process & Chemical Engineering

Investigation into Alternate Dosing Methods of Clean in Place (CIP) Skids

2025

Mark Kenny

ME in Process & Chemical Engineering

Modelling and Predicting Cellular Growth in Bioreactors: Insights and Implications

2025

Jody Sisk

MEngSc in Industrial Biotechnology and Biomanufacturing

Optimisation of a Bioprocess for Whey Permeate Valorisation using Kluyveromyces marxianus

2025

Eleni Kapeti

MEngSc in Industrial Biotechnology and Biomanufacturing

Optimization of Mycoprotein Production using Potato Processing Waste: A Circular Bioeconomy Approach

2025

Barry Ryan

MEngSc in Industrial Biotechnology and Biomanufacturing

Commissioning & Qualification of a Perfusion Bioreactor and TFF Skid System to Increase Cell Culture Capacity in a Multidrug Biotechnology Drug Substance Manufacturing Facility

2024

Ina Bremenkamp

PhD in Process & Chemical Engineering 

Sustainable Food Packaging Engineering

2024

Adam James Carroll

MEngSc in Industrial Biotechnology and Biomanufacturing

Moving Towards Optimisation and Sustainable Production of Docosahexaenoic Acid from Schizochytrium S31

2024

Brian O’Neill

ME in Process & Chemical Engineering

Bioreactors Operation: Investigation into The Commissioning and Qualification Process

2024

Sibéal McGrath

ME in Process & Chemical Engineering

Effect of the Revised EU GMP Annex 1 Guidelines on the Manufacture of Biopharmaceuticals 

2024

Cathal Bane

ME in Process & Chemical Engineering

Intermittent Failures of BIs during Gas Cycle Development complete

2023

Fiona Luttrell

ME in Process & Chemical Engineering

Single-Pass Tangential Flow Filtration (SPTFF) for the Production of High Final Concentration Biopharmaceuticals

2023

George Dwyer

ME in Process & Chemical Engineering

Buffer Production Optimisation

2023

Jill Donegan

ME in Process & Chemical Engineering

Optimising Harvest and Clarification for Biopharmaceutical Production

2023

Sean Devereaux-Heddon

ME in Process & Chemical Engineering

Feasibility study for the introduction of biopharmaceutical ‘Product A’ to a semi-automated packaging line

2023

Neil Kenny

MEngSc in Pharmaceutical & Biopharmaceutical Engineering

Custom Equipment Replacement with Minimal Downtime 

2023

Gerard John O’Connell

MEngSc in Pharmaceutical & Biopharmaceutical Engineering

Evaluation into the use of Movement Bed Biofilm Reactor for commercial wastewater treatment

2022

Julian Power

ME in Process & Chemical Engineering

Evaluation into use of multi-product Ultrafiltration/Diafiltration skid in Biopharmaceutical downstream purification

2022

Eoghan O’Leary

ME in Process & Chemical Engineering

Quality by Design within the Bioprocessing Sector

2022

Ciarr O’Connor

ME in Process & Chemical Engineering

Applications and Treatment of Biopharmaceutical Wastewater Sludge at Janssen Sciences Ireland

2022

Seán Anthony Kelly

ME in Process & Chemical Engineering

Use of Raman chemometric modelling as a process analytical technology (PAT) toll for optimising in-process monitoring

2022

Bernadette O’Mahony

MEngSc in Pharmaceutical & Biopharmaceutical    Engineering

Modularisation of Biopharmaceutical Cleanrooms in Facilities of the Future

2022

James Delaney

MEngSc in Pharmaceutical & Biopharmaceutical Engineering

Single Use Technology & Perfusion Platforms to Replace Traditional Stainless Steel Fed Batch Platforms in the Biopharmaceutical Industry

2022

Karl Preston

MEngSc in Pharmaceutical & Biopharmaceutical Engineering

Improvements across the Commissioning & Qualification of critical equipment and services in the Biopharmaceutical sector

2022

Noel P. McLaughlin

MEngSc in Pharmaceutical & Biopharmaceutical Engineering

Water Removal from Pharmaceutical Processes by Pervaporation

2021

 Bill Sheehan

ME in Process & Chemical Engineering

Media Filtration optimization in the production of Vimizim 

2021

Josephine Fennell

ME in Process & Chemical Engineering

Constrained design methodology applied to a bio-based composite film

2021

Peter A. O’Leary

MEngSc in Pharmaceutical & Biopharmaceutical Engineering

Phosphorus Reduction in Biopharmaceutical & Pharmaceutical Manufacturing

2021

Ben Harte

MEngSc in Pharmaceutical & Biopharmaceutical Engineering

Membrane WFI Generation and Utilisation of point of use coolers

2021

Caroline Barry

MEngSc in Pharmaceutical & Biopharmaceutical Engineering

An Assessment of the Current Single-Use Technology Industry Trends and Application in the PCV Project

2021

Teresa Gaire

MEngSc in Pharmaceutical & Biopharmaceutical Engineering

WFI Capacity Expansion

2021

Michael Bruton

MEngSc in Pharmaceutical & Biopharmaceutical Engineering

 Study of WFI Generation Methods and Alternative Technologies

2021

Michael Egan

MEngSc in Pharmaceutical & Biopharmaceutical Engineering

Application of Extended Reality in Life Sciences

2021

Kevin Hayes

MEngSc in Pharmaceutical & Biopharmaceutical Engineering

The Application of Side Discharge Valves in Multipurpose Pharmaceutical Operations

2021

Alan Hayes

MEngSc in Pharmaceutical & Biopharmaceutical Engineering

Cleaning Validation of Blender / Packer

2021

David Linnane

MEngSc in Pharmaceutical & Biopharmaceutical Engineering

 Quality by design and PAT as an alternative approach to Quality by testing in Biopharmaceutical Cell Culture

2021

Grace Ellen Kevany 

MEngSc in Pharmaceutical & Biopharmaceutical Engineering

Clean Steam Generation: An Investigation into the Commissioning and Qualification Process

2021

Khadija Mu’azzam

MEngSc in Pharmaceutical & Biopharmaceutical Engineering

Process Simulators towards virtual Digital Twins in the Biopharmaceutical Industry

2021

Steven O’Reilly

MEngSc in Pharmaceutical & Biopharmaceutical Engineering

Technical Transfer of a New Product and Performance Qualification

2021

Jessica Barrett

MEngSc in Pharmaceutical & Biopharmaceutical Engineering

Bioreactor Design and Scale Up Considerations for High-Titre Monoclonal Antibodies

2021

Owen Fetherstonhaugh

MEngSc in Pharmaceutical & Biopharmaceutical Engineering

Optimisation of a Flue Gas Treatment System in the Waste to Energy Industry

2021

Jason Homan

MEngSc in Pharmaceutical & Biopharmaceutical Engineering

A Sustainability Study of Waste Methanol from an Active Pharmaceutical Ingredient Plant

2020

Johnathan Walsh

MEngSc in Pharmaceutical & Biopharmaceutical Engineering

A study into the benefits of an asset centric approach in the construction stage of the project life cycle

2020

Louise Moran

MEngSc in Pharmaceutical & Biopharmaceutical Engineering

Reformulation of Denture Cleansing Tablets to Improve Tabletting Robustness

2020

Eoin O’Sullivan

MEngSc in Pharmaceutical & Biopharmaceutical Engineering

Examining the Implementation of Commercial Scale Single Use Bioreactors for Bioprocessing Applications: A Comparative Analysis

2020

Chris O’Donnell

MEngSc in Pharmaceutical & Biopharmaceutical Engineering

Design of a Pharmaceutical Water Generation, Storage and Distribution System for a Biopharmaceutical Bulk Drug Substance Production Facility

2019

Raghu V. G. Peddapatla

PHD in Pharmacy

A Study of Magnesium Sterate Behaviour in Pharmaceutical Blends and Tablets

 

Research Grants

Title of ProjectAwarding BodyAmount AwardedGrant Period
Smart and eco-innovative SEAFOOD processes and products for healthy AGEing (SEAFOOD-AGE) EU-INTERREG Atlantic Area  (WP leader, and UCC PI)€2,926,187.90, UCC: €280,649May 2019- Oct 2022
Recycling of End-of-Life Products (PCB, ASR, LCD) (RecEOL)   EU-ERAMIN2/GSI/EPA (IRE) (Coordinator, and UCC PI)€1,299.163, UCC: €192,401.00June 2018- Oct 2021

UCC Futures (primary)

  • Future of Sustainable Fermentation (SUSFERM)

Other research affiliations

  • UCC Futures - Sustainability Institute

PhD Supervision

  • Available for PhD supervision

Expertise related to UN Sustainable Development Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):

  1. SDG 4 - Quality Education
    SDG 4 Quality Education
  2. SDG 8 - Decent Work and Economic Growth
    SDG 8 Decent Work and Economic Growth
  3. SDG 9 - Industry, Innovation, and Infrastructure
    SDG 9 Industry, Innovation, and Infrastructure
  4. SDG 12 - Responsible Consumption and Production
    SDG 12 Responsible Consumption and Production
  5. SDG 17 - Partnerships for the Goals
    SDG 17 Partnerships for the Goals

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