Personal profile
Biography
In a scientific career initiated with a B.Sc. in Biochemistry from the University of St. Andrews, Scotland and a Ph.D from the Medical Research Council, Institute of Virology, Glasgow; I ventured to Cambridge, England and back to Scotland again for post doctoral research experience in viral pathogenesis before becoming established at UCC. I now teach and examine over 500 undergraduate students every year ( in the second, third and fourth years of their degrees), with responsibility for lecture modules encompassing Virology, Epidemiology and Microbial Pathogenesis. Each year I also host undergraduate fourth year research projects in Virology and Cell Biology for the Microbiology and Biomedical Science B.Sc. degrees (4 to 5) and Postgraduate Projects for the M.Sc. in Molecular Cell Biology and Bio-innovation and M.Sc. Biomedical Science. In addition to other administrative roles, I have chaired the School of Microbiology Teaching, Learrning and Student Experience committee (TLSE) and the Teaching & Curriculum Development committee and have been an active member of the corresponding college-level committees.With research expertise in classical and molecular virology and cell culture, I established a Category II Virus Research Laboratory at UCC, and have been happy to welcome collaborators. In that environment I have trained and supervised 9 PhD and 9 M.Sc. students to graduation. With research projects directed towards dissecting the molecular interplay between viruses and their host cells. Collaboration within and beyond UCC has supported our research in the field of virus vectors for therapeutic intervention in the face of cancer, neurodegeneration and genetic disease. Innovation funding has recently supported our investigation of 3-D culture systems as a platform for virus-vector based production systems.
Research Interests
UCC Futures (primary)
- Future Pharmaceuticals
PhD Supervision
- Available for PhD supervision
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
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Collaborations and top research areas from the last five years
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Adenine base editing with engineered virus-like particles rescues the CFTR mutation G542X in patient-derived intestinal organoids
Nicosia, L., Pranke, I., Latorre, R. V., Murray, J. B., Lonetti, L., Cavusoglu-Doran, K., Dreano, E., Costello, J. P., Carroll, M., Melotti, P., Sorio, C., Sermet-Gaudelus, I., Scallan, M. F. & Harrison, P. T., 21 Mar 2025, In: iScience. 28, 3, 111979.Research output: Contribution to journal › Article › peer-review
Open Access -
Student informed development of virtual reality simulations for teaching and learning in the molecular sciences
Reen, F. J., Jump, O., McEvoy, G., McSharry, B. P., Morgan, J., Murphy, D., O’Leary, N., O’Mahony, B., Scallan, M., Walsh, C. & Supple, B., 2025, In: Journal of Biological Education. 59, 4, p. 604-620 17 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Use of adenine base editing and homology-independent targeted integration strategies to correct the cystic fibrosis causing variant, W1282X
Mention, K., Cavusoglu-Doran, K., Joynt, A. T., Santos, L., Sanz, D., Eastman, A. C., Merlo, C., Langfelder-Schwind, E., Scallan, M. F., Farinha, C. M., Cutting, G. R., Sharma, N. & Harrison, P. T., 1 Dec 2023, In: Human Molecular Genetics. 32, 23, p. 3237-3248 12 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Developing student codesigned immersive virtual reality simulations for teaching of challenging concepts in molecular and cellular biology
Jerry Reen, F., Jump, O., McEvoy, G., McSharry, B. P., Morgan, J., Murphy, D., O'Leary, N., O'Mahony, B., Scallan, M., Walsh, C. & Supple, B., 2022, In: FEMS Microbiology Letters. 369, 1, fnac051.Research output: Contribution to journal › Article › peer-review
Open Access -
Student partnered design of Immersive Virtual Reality Simulations
Reen, F. J., Jump, O., McSharry, B. P., Morgan, J., Murphy, D., O'Leary, N., O'Mahony, B., Scallan, M., McEvoy, G., Walsh, C. & Supple, B., 8 Nov 2021.Research output: Contribution to conference › Poster › peer-review