1994 …2025

Research activity per year

Personal profile

Biography

Professor Noel Caplice is Professor of Cardiovascular Sciences in the Department of Medicine and Director of the Centre for Research in Vascular Biology at University College Cork. He is also a Consultant Cardiologist at Cork University Hospital. He previously held professional positions in pharmacology and medicine at the Mayo Clinic, Rochester, Minnesota, USA, where he was an interventional cardiologist and directed the Vascular Stem Cell Laboratory. Professor Caplice Centre for Research in Vascular Biology research programme is addressing fundamental questions in vascular stem cell biology, atherosclerosis and vascular remodeling with emphasis on translation of ideas to the clinical cardiology arena in areas of novel diagnostics and therapeutics in the field of stem cells, gene delivery and tissue engineering.

Research Interests

1. Detection of human smooth muscle progenitor cells in blood and  human atherosclerotic plaque.  2.Determinatiing the cardiac repair potential of specific cytoprotective factors in models of myocardilal infarction3. Realtime tracking of stem cells in vivo and evaluation of paracrine cardiomyocyte repair effects of progenitor cells 4. Biology of vacsular progenitor cells and smooth muscle progenitor cells in animal models of atheroaclerosis, graft engineering, remodeling after stent injury and myocardial infarction

Teaching Activities

Undergraduate and graduate medical students-clinical cardiologyDoctorate and postdoctorate science graduates-vascular biology Core interests are in the areas of interventional cardiology as it relates to cardiac repair, vascular biology, vascular disease, translational medicine and novel therapeutics

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