Personal profile
Biography
Biography Dr. Rachel D Moloney received a B.Sc. (Hons) in Biochemistry from UCC in 2009 after which she received an M.Sc. in Neuropharmacology from National University of Ireland, Galway (NUIG). She completed her Ph.D. in the Dept. of Psychiatry and Dept. Anatomy & Neuroscience, UCC in 2014, followed by post-doctoral research at APC Microbiome Ireland. Rachel then pursued post-doctoral fellowships at the University of Oklahoma Health Sciences Center, Oklahoma City, USA and the University of Cincinnati, Ohio, USA. During this time, she was awarded a prestigious NARSAD Young Investigator Award from the Brain and Behaviour Research foundation (USA). In December 2019, Rachel took up her position as Lecturer in the School of Pharmacy and Dept. of Pharmacology & Therapeutics, University College Cork and in 2022 she progressed across the Merit bar. Research Interests Rachel’s current research is focused on understanding the role of traumatic stress on brain circuitry and its impact on empathy-related behaviours, particularly in the context of post-traumatic stress disorder (PTSD), pain, anxiety and depression. Her lab focuses on stress neurobiology across the lifespan, utilizing cutting edge tools such as chemogenetics and other viral vector strategies (TRAP) to manipulate specific brains areas and unravel neuronal circuits. In parallel with this, Rachel is interested in the role of the gut microbiome in mediating the bi-directional communication between these brain circuits and the gut, with the goal to elucidate potential pathways which may be targeted for future therapies of stress-related illnesses.
Research Interests
Dr. Moloney's current research is focused on understanding the role of traumatic stress on brain circuitry and its impact on fear and social behaviours, particularly in the context of PTSD, anxiety and depression. Her lab focuses on stress neurobiology across the lifespan, utilizing cutting edge tools such as DREADDs to manipulate neuro-circuitry and to unravel these corticolimbic circuits. Dr. Moloney is also interested in the role of the brain-gut microbiome axis in stress-related illnesses as well as the impact of stress on pain sensitivity and spinal circuitry.
Teaching Activities
PT1445 (Module coordinator) PT2448 (Module coordinator) PF2011 PF3009 PF3012 PF4014 PF4016 PF6421 PT4023 PT4024 MH4010 PT6401 (Module coordinator)
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Collaborations and top research areas from the last five years
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Behavioral assessment of neuropsychiatric outcomes in rodent stroke models
Callaghan, R. M., Yang, H., Moloney, R. D. & Waeber, C., Jul 2025, In: Journal of Cerebral Blood Flow and Metabolism. 45, 7, p. 1232-1248 17 p.Research output: Contribution to journal › Review article › peer-review
Open Access -
General Practitioners’ Views on Mental Health Following Stroke: Findings from a Cross-Sectional Study
Callaghan, R. M., Dalton, K., Foley, T., Moloney, R. D., Waeber, C. & Hartigan, I., Dec 2025, In: Age and Ageing.Research output: Contribution to journal › Meeting abstract › peer-review
Open Access -
Regulation of behavioral responses to single prolonged stress in male and female rats: Role of PACAP
Smail, M. A., Cotella, E. M., Martelle, S. E., Chambers, J. B., Parikh, R. K., Moore, C. E., Packard, B. A., Nawreen, N., Moloney, R. D. & Herman, J. P., May 2025, In: Neurobiology of Stress. 36, 100727.Research output: Contribution to journal › Article › peer-review
Open Access -
Understanding Post-Stroke Mental Health in Primary Care: A Cross-Sectional Survey of General Practitioners' Views on Depression, Anxiety, Apathy, and Fatigue
Callaghan, R., Dalton, K., Foley, T., Moloney, R., Waeber, C. & Hartigan, I., Nov 2025, In: International Journal of Stroke. 20, 3_SUPPL, 2 p.Research output: Contribution to journal › Meeting abstract › peer-review
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A novel animal model for understanding secondary traumatic stress and visceral pain in male rats
Lannon, A. S., Brocka, M., Collins, J. M., Fitzgerald, P., O'Mahony, S. M., Cryan, J. F. & Moloney, R. D., Jul 2024, In: European Journal of Neuroscience. 60, 1, p. 3544-3556 13 p.Research output: Contribution to journal › Article › peer-review
Open Access
Press/Media
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University College Cork Reports Findings in Anxiety Disorders (Social fear extinction susceptibility is associated with Microbiota-Gut-Brain axis alterations)
Shkoporov, A., Draper, L., Moloney, G., Hill, C. & Moloney, R. D.
24/06/24
1 item of Media coverage
Press/Media
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Studies in the Area of Visceral Pain Reported from University College Cork (A Novel Animal Model for Understanding Secondary Traumatic Stress and Visceral Pain In Male Rats)
Fitzgerald, P., Cryan, J. F., Moloney, R. D., O'Mahony, S. & Collins, M.
4/06/24
1 item of Media coverage
Press/Media