Personal profile
Biography
Sean Mathieson has been working at the INFANT Centre, UCC, Cork as a Neurophysiologist since 2017.
After completing a BSc in Biology in Bath and an MSc in Neuroscience at UCL, Sean trained and worked as a Clinical Physiologist at Great Ormond Street hospital from 2001-2009 in the EEG department performing EEG (brainwave) recordings and other neurophysiological tests on children with epilepsy. He worked in the Neonatal Brain Research Group from 2009 – 2016, working at UCLH in London to recruit and record EEG on neonates at risk of seizures for the ANSeR study to test an automated seizure detection algorithm for neonatal EEG. During this time he studied for a PhD which involved analysis of various aspects of the performance of the ANSeR algorithm.
Research Interests
Sean Mathieson specialises in the area of neonatal neurophysiology. He has previously worked on the ANSeR project to devise and test an automated algorithm to detect neonatal seizures, the Delphi project to test an automated algorithm for grading of the background EEG, and the BabySMART project investigating the effect of parent-led massage on the EEG of term born healthy infants.
Sean is currently involved in several EEG projects, including; development of an AI-based newborn brain screener (Wave); the AIM HIGH project to investigate early EEG biomarkers of cerebral Palsy; and the ACUMEN study to investigate Melatonin as a neuroprotectant for neonatal hypoxic Ischaemic Encephalopathy.
Recent PhD Students
Dr Mary Anne Ryan. 'Sleep and developmental outcome of the moderate to late preterm infant' 2023.
Dr Soraia Ventura. 'Electroencephalographic Study of Sleep Architecture in Infants at Four Months' 2024.
Current PhD Students
Sonia M Lenehan 'Investigating the effect of breastfeeding, massage, and moderate-to-late preterm birth on the developing brain.'
UCC Futures (primary)
- Future of Health
Other research affiliations
- UCC Futures - Artificial Intelligence and Data Analytics
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Collaborations and top research areas from the last five years
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Classification of Hypoxic Ischemic Encephalopathy (HIE) in neonates using ECG and a transformer-based model
Rezaei, K., Mathieson, S. R., Lightbody, G., Boylan, G. B. & Marnane, W. P., 9 Feb 2026, In: IEEE Access. 14, p. 24298-24311 14 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
Background EEG grading for the assessment of neonatal encephalopathy in full term neonates
Fanning, A., Pegorer, E., Pavel, A. M., Mathieson, S. R., Walsh, B. H. & Boylan, G. B., Dec 2025, In: Seminars in Perinatology. 49, 8, p. 152163Research output: Contribution to journal › Review article › peer-review
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Epilepsy following neonatal encephalopathy—Future directions
Stephens, C. M., Proietti, J., Mathieson, S. R., Livingstone, V., McNamara, B., McSweeney, N., O'Mahony, O., Walsh, B. H., Murray, D. M. & Boylan, G. B., Apr 2025, In: Epilepsia Open. 10, 2, p. 656-657 2 p.Research output: Contribution to journal › Letter › peer-review
Open Access -
Incidence and Predictors of Later Epilepsy in Neonates with Encephalopathy: The Impact of Electrographic Seizures
Stephens, C. M., Proietti, J., Mathieson, S. R., Livingstone, V., McNamara, B., McSweeney, N., O'Mahony, O., Walsh, B. H., Murray, D. M. & Boylan, G. B., Feb 2025, In: Epilepsia Open. 10, 1, p. 155-167 13 p.Research output: Contribution to journal › Article › peer-review
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Infant sleep EEG features at 4 months as biomarkers of neurodevelopment at 18 months
Ventura, S., Mathieson, S. R., O’Toole, J. M., Livingstone, V., Murray, D. M. & Boylan, G. B., 2025, (Accepted/In press) In: Pediatric Research. 107415.Research output: Contribution to journal › Article › peer-review
Open Access
Press/Media
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University College Cork Reports Findings in Seizures (Incidence and Predictors of Later Epilepsy in Neonates with Encephalopathy: The Impact of Electrographic Seizures)
Boylan, G., Murray, D., Mathieson, S., Livingstone, V. & Walsh, B.
1/01/25
1 item of Media coverage
Press/Media
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New Pediatrics Study Results from University College Cork Described (Neurodevelopmental outcome of low-risk moderate to late preterm infants at 18 months)
Boylan, G., Murray, D., Mathieson, S., Livingstone, V., Dempsey, E. & Ryan, M.
18/12/23
1 item of Media coverage
Press/Media