Personal profile
Biography
Dr Sophie Casey received a BSc Hons degree in Neuroscience from University College Cork in 2016. Following this, she pursued a PhD in the area of paediatric neuroimmunology, during which time she examined the temporal alterations in inflammation-driven molecular markers in clinical and preclinical cases of hypoxic ischemic encephalopathy with and without inflammatory sensitisation, as well as autism spectrum disorders. She was awarded a PhD in Medicine from University College Cork in 2021.
Dr Casey's current research focuses on the investigation of novel psychedelic inspired neuroprotective therapies for diseases and disorders with an inflammatory milieu, and the specific mechanisms by which these compounds act within the nervous system.
Research Interests
My research interests lie within the area of psychedelic and psychedelic-derived compounds, particularly for the treatment of diseases and disorders with an inflammatory milieu, such as neurodegenerative diseases.
My current research focuses on the potential neuroprotective and immunomodulatory action of psychedelic ayahuasca-derived harmala alkaloids in cellular models of Parkinson's Disease.
Teaching Activities
FM1010/MH1010 Foundations of Medicine I - Introductory Human Biology
FM1040/MH1040 Foundations of Medicine IV - Gastrointestinal, Nutritional & Metabolic Biology
FM2101/MH2101 Foundations of Medicine - Neuroscience
GM2001 Fundamentals of Medicine IV
MH1050 Introduction to Translational Research
MH2020 Research Methods in Medical Sciences
PL2033 The Nervous System *Module coordinator
PL3020 Neurophysiology *Module coordinator
PL3024 Digestive Physiology *Module coordinator
I also contribute to MH3010 Structured Literature Project in Medical & Health Sciences, MH4010 Research Project in Medical & Health Sciences, PL3025 Literature Review, Experimental Design & Data Analysis, & PL4020 Research Project in Physiology as a supervisor. To date, I have supervised >15 BSc Medical & Health Science & BSc Physiology final year research projects on the topic of psychedelic-derived compounds for neuroprotection in neurodegeneration.
UCC Futures (primary)
- Future Ageing and Brain Science
Fingerprint
- 1 Similar Profiles
Research output
- 7 Article
-
Maternal Immune Activation and Interleukin 17A in the Pathogenesis of Autistic Spectrum Disorder and Why It Matters in the COVID-19 Era
Carter, M., Casey, S., O'Keeffe, G. W., Gibson, L., Gallagher, L. & Murray, D. M., 17 Feb 2022, In: Frontiers in Psychiatry. 13, 823096.Research output: Contribution to journal › Article › peer-review
Open Access -
Maternal Mid-Gestation Cytokine Dysregulation in Mothers of Children with Autism Spectrum Disorder
the SCOPE Consortium, Sep 2022, In: Journal of Autism and Developmental Disorders. 52, 9, p. 3919-3932 14 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Early-life oxytocin attenuates the social deficits induced by caesarean-section delivery in the mouse
Morais, L. H., Golubeva, A. V., Casey, S., Scott, K. A., Ramos Costa, A. P., Moloney, G. M., Dinan, T. G. & Cryan, J. F., Oct 2021, In: Neuropsychopharmacology. 46, 11, p. 1958-1968 11 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Mid-gestation cytokine profiles in mothers of children affected by autism spectrum disorder: a case–control study
Carter, M., Casey, S., O’Keeffe, G. W., Gibson, L. & Murray, D. M., Dec 2021, In: Scientific Reports. 11, 1, 22315.Research output: Contribution to journal › Article › peer-review
Open Access -
Up-Regulation of Nfat5 mRNA and Fzd4 mRNA as a Marker of Poor Outcome in Neonatal Hypoxic-Ischemic Encephalopathy
O'Sullivan, M. P., Casey, S., Finder, M., Ahearne, C., Clarke, G., Hallberg, B., Boylan, G. B. & Murray, D. M., Jan 2021, In: Journal of Pediatrics. 228, p. 74-81.e2Research output: Contribution to journal › Article › peer-review