1,3-Dipolar cycloadditions of 2-thio-3-chloroacrylamides with nitrile oxides and nitrones

Marie Kissane; Simon E. Lawrence; Anita R. Maguire

doi:10.1016/j.tet.2010.04.057

1,3-Dipolar cycloadditions of 2-thio-3-chloroacrylamides with nitrile oxides and nitrones

School of Chemistry

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Abstract

1,3-Dipolar cycloadditions of 2-thio-3-chloroacrylamides with nitrile oxides and nitrones is described. A series of novel isoxazolines are isolated from the nitrile oxide cycloadditions, whilst the isoxazolines generated from the nitrone cycloadditions undergo further ring opening to yield piperidines.

Original language	English
Pages (from-to)	4564-4572
Number of pages	9
Journal	Tetrahedron
Volume	66
Issue number	25
DOIs	https://doi.org/10.1016/j.tet.2010.04.057
Publication status	Published - 19 Jun 2010

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10.1016/j.tet.2010.04.057

https://hdl.handle.net/10468/588Licence: CC BY-NC-ND

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title = "1,3-Dipolar cycloadditions of 2-thio-3-chloroacrylamides with nitrile oxides and nitrones",

abstract = "1,3-Dipolar cycloadditions of 2-thio-3-chloroacrylamides with nitrile oxides and nitrones is described. A series of novel isoxazolines are isolated from the nitrile oxide cycloadditions, whilst the isoxazolines generated from the nitrone cycloadditions undergo further ring opening to yield piperidines.",

author = "Marie Kissane and Lawrence, \{Simon E.\} and Maguire, \{Anita R.\}",

year = "2010",

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doi = "10.1016/j.tet.2010.04.057",

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AU - Kissane, Marie

AU - Lawrence, Simon E.

AU - Maguire, Anita R.

PY - 2010/6/19

Y1 - 2010/6/19

N2 - 1,3-Dipolar cycloadditions of 2-thio-3-chloroacrylamides with nitrile oxides and nitrones is described. A series of novel isoxazolines are isolated from the nitrile oxide cycloadditions, whilst the isoxazolines generated from the nitrone cycloadditions undergo further ring opening to yield piperidines.

AB - 1,3-Dipolar cycloadditions of 2-thio-3-chloroacrylamides with nitrile oxides and nitrones is described. A series of novel isoxazolines are isolated from the nitrile oxide cycloadditions, whilst the isoxazolines generated from the nitrone cycloadditions undergo further ring opening to yield piperidines.

UR - https://www.scopus.com/pages/publications/77953119802

U2 - 10.1016/j.tet.2010.04.057

DO - 10.1016/j.tet.2010.04.057

M3 - Article

AN - SCOPUS:77953119802

SN - 0040-4020

VL - 66

SP - 4564

EP - 4572

JO - Tetrahedron

JF - Tetrahedron

IS - 25

ER -

1,3-Dipolar cycloadditions of 2-thio-3-chloroacrylamides with nitrile oxides and nitrones

Abstract

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